TreeWAS – Variant ID: rs2523627

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
E10.3 With ophthalmic complications	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E10-E14 Diabetes mellitus	0.000	0.000	1.000
E14 Unspecified diabetes mellitus	0.000	0.000	1.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.000	1.000
K51 Ulcerative colitis	1.000	0.000	0.000
E14.9 Without complications	0.000	0.000	1.000
E10.1 With ketoacidosis	0.000	0.001	0.999
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.002	0.998
K51.9 Ulcerative colitis, unspecified	0.997	0.003	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.004	0.996
E20-E35 Disorders of other endocrine glands	0.000	0.004	0.996
E11.3 With ophthalmic complications	0.000	0.005	0.995
M45 Ankylosing spondylitis	0.000	0.005	0.995
E16 Other disorders of pancreatic internal secretion	0.000	0.005	0.995
K50 Crohn's disease [regional enteritis]	0.993	0.007	0.000
K50-K52 Noninfective enteritis and colitis	0.993	0.007	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.007	0.993
K51.3 Ulcerative (chronic) rectosigmoiditis	0.993	0.007	0.000
M06 Other rheumatoid arthritis	0.000	0.008	0.992
E27 Other disorders of adrenal gland	0.000	0.008	0.992
G35 Multiple sclerosis	0.991	0.009	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.012	0.988
K50.9 Crohn's disease, unspecified	0.985	0.015	0.000
E10.4 With neurological complications	0.000	0.019	0.981
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.023	0.977
K50.0 Crohn's disease of small intestine	0.975	0.025	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.028	0.972
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.029	0.971
K51.4 Pseudopolyposis of colon	0.969	0.031	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.033	0.967
M06.3 Rheumatoid nodule	0.000	0.035	0.965
K51.2 Ulcerative (chronic) proctitis	0.965	0.035	0.000
J45.9 Asthma, unspecified	0.000	0.038	0.962
E11.1 With ketoacidosis	0.000	0.040	0.960
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.044	0.956
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.051	0.949
M05-M14 Inflammatory polyarthropathies	0.000	0.065	0.935
E11.5 With peripheral circulatory complications	0.000	0.073	0.927
M05 Seropositive rheumatoid arthritis	0.000	0.074	0.926
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.078	0.922
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.083	0.917
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.097	0.903
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.105	0.895
K51.8 Other ulcerative colitis	0.892	0.108	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.113	0.887
E10.8 With unspecified complications	0.000	0.115	0.885
E10.2 With renal complications	0.000	0.116	0.884
E10.0 With coma	0.000	0.118	0.882
E11.9 Without complications	0.000	0.119	0.881
E14.3 With ophthalmic complications	0.000	0.120	0.880
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.123	0.877
M07 Psoriatic and enteropathic arthropathies	0.000	0.125	0.875
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.125	0.875
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.126	0.874
E10.5 With peripheral circulatory complications	0.000	0.127	0.873
E11.2 With renal complications	0.000	0.132	0.868
E23 Hypofunction and other disorders of pituitary gland	0.000	0.142	0.858
M06.34 Rheumatoid nodule (Hand)	0.000	0.143	0.857
K50.1 Crohn's disease of large intestine	0.846	0.154	0.000
E22 Hyperfunction of pituitary gland	0.000	0.160	0.840
M07.3 Other psoriatic arthropathies	0.000	0.161	0.839
E28 Ovarian dysfunction	0.000	0.165	0.835
E14.1 With ketoacidosis	0.000	0.170	0.830
E14.8 With unspecified complications	0.000	0.177	0.823
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.182	0.818
H36.0 Diabetic retinopathy	0.000	0.185	0.815
E10.6 With other specified complications	0.000	0.186	0.814
G35-G37 Demyelinating diseases of the central nervous system	0.805	0.195	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.201	0.799
I10 Essential (primary) hypertension	0.000	0.209	0.791
K51.5 Mucosal proctocolitis	0.783	0.217	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.224	0.776
E14.6 With other specified complications	0.000	0.229	0.771
G37 Other demyelinating diseases of central nervous system	0.765	0.235	0.000
E11.0 With coma	0.000	0.238	0.762
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.239	0.761
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.245	0.755
E27.9 Disorder of adrenal gland, unspecified	0.000	0.247	0.753
E25 Adrenogenital disorders	0.000	0.247	0.752
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.250	0.749
E23.7 Disorder of pituitary gland, unspecified	0.000	0.252	0.748
M06.4 Inflammatory polyarthropathy	0.000	0.256	0.744
E16.1 Other hypoglycaemia	0.000	0.259	0.741
E24 Cushing's syndrome	0.000	0.263	0.737
G37.9 Demyelinating disease of central nervous system, unspecified	0.731	0.269	0.000
E11.4 With neurological complications	0.000	0.273	0.727
E23.2 Diabetes insipidus	0.000	0.276	0.724
E00-E07 Disorders of thyroid gland	0.000	0.279	0.721
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.280	0.720
E28.2 Polycystic ovarian syndrome	0.000	0.281	0.719
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.282	0.718
E14.5 With peripheral circulatory complications	0.000	0.282	0.718
E10.7 With multiple complications	0.000	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
E14.7 With multiple complications	0.000	0.283	0.717
E14.0 With coma	0.000	0.283	0.717
E11.7 With multiple complications	0.000	0.283	0.717
E26 Hyperaldosteronism	0.000	0.283	0.716
E15 Nondiabetic hypoglycaemic coma	0.000	0.286	0.714
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.286	0.714
E32 Diseases of thymus	0.000	0.286	0.714
E31 Polyglandular dysfunction	0.000	0.286	0.714
E30 Disorders of puberty, not elsewhere classified	0.000	0.286	0.714
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.286	0.713
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.286	0.713
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.286	0.713
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.286	0.713
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.286	0.713
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.286	0.713
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.287	0.713
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.287	0.713
E16.4 Abnormal secretion of gastrin	0.000	0.287	0.713
E16.3 Increased secretion of glucagon	0.000	0.287	0.713
M06.8 Other specified rheumatoid arthritis	0.000	0.287	0.713
M06.2 Rheumatoid bursitis	0.000	0.288	0.711
M06.1 Adult-onset Still's disease	0.000	0.288	0.711
E27.5 Adrenomedullary hyperfunction	0.000	0.289	0.711
E27.0 Other adrenocortical overactivity	0.000	0.289	0.711
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.289	0.711
E14.4 With neurological complications	0.000	0.290	0.710
M05.8 Other seropositive rheumatoid arthritis	0.000	0.295	0.705
E20 Hypoparathyroidism	0.000	0.296	0.704
E29 Testicular dysfunction	0.000	0.307	0.693
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.308	0.692
M06.38 Rheumatoid nodule (Other)	0.000	0.308	0.692
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.308	0.692
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.308	0.692
M06.33 Rheumatoid nodule (Forearm)	0.000	0.308	0.692
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.308	0.692
E05.9 Thyrotoxicosis, unspecified	0.000	0.309	0.691
M12 Other specific arthropathies	0.000	0.315	0.685
E13 Other specified diabetes mellitus	0.000	0.316	0.684
E14.2 Withrenal complications	0.000	0.320	0.680
E22.0 Acromegaly and pituitary gigantism	0.000	0.320	0.680
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.322	0.678
M06.0 Seronegative rheumatoid arthritis	0.000	0.327	0.673
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.329	0.671
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.330	0.670
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.333	0.667
E23.6 Other disorders of pituitary gland	0.000	0.333	0.667
K51.1 Ulcerative (chronic) ileocolitis	0.666	0.334	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.336	0.664
M05.1 Rheumatoid lung disease	0.000	0.336	0.664
M05.0 Felty's syndrome	0.000	0.336	0.664
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.339	0.661
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.339	0.661
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.339	0.661
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.339	0.661
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.339	0.661
M08 Juvenile arthritis	0.000	0.340	0.660
E11.8 With unspecified complications	0.000	0.341	0.659
I10-I15 Hypertensive diseases	0.000	0.349	0.651
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.351	0.648
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.362	0.638
M14 Arthropathies in other diseases classified elsewhere	0.000	0.363	0.637
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.365	0.634
M07.5 Arthropathy in ulcerative colitis	0.000	0.372	0.628
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.372	0.628
M07.2 Psoriatic spondylitis	0.000	0.372	0.628
M07.1 Arthritis mutilans	0.000	0.372	0.628
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.372	0.628
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.378	0.622
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.384	0.615
E23.1 Drug-induced hypopituitarism	0.000	0.384	0.615
E22.1 Hyperprolactinaemia	0.000	0.387	0.613
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.610	0.390	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.390	0.610
E40-E46 Malnutrition	0.000	0.396	0.604
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.397	0.603
E22.8 Other hyperfunction of pituitary gland	0.000	0.397	0.603
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.399	0.601
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.399	0.601
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.399	0.601
I12 Hypertensive renal disease	0.000	0.400	0.600
E28.3 Primary ovarian failure	0.000	0.401	0.599
E28.9 Ovarian dysfunction, unspecified	0.000	0.402	0.598
E28.8 Other ovarian dysfunction	0.000	0.402	0.598
E28.1 Androgen excess	0.000	0.402	0.598
E28.0 Oestrogen excess	0.000	0.402	0.598
E11.6 With other specified complications	0.000	0.405	0.595
G36 Other acute disseminated demyelination	0.591	0.409	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.410	0.590
E27.2 Addisonian crisis	0.000	0.411	0.589
I15 Secondary hypertension	0.000	0.414	0.586
M07.6 Other enteropathic arthropathies	0.000	0.415	0.585
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.422	0.578
E27.8 Other specified disorders of adrenal gland	0.000	0.424	0.576
E34 Other endocrine disorders	0.000	0.425	0.575
K50.8 Other Crohn's disease	0.568	0.432	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.436	0.564
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.440	0.560
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.444	0.556
E24.0 Pituitary-dependent Cushing's disease	0.000	0.445	0.555
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.445	0.554
I15.9 Seconday hypertension, unspecified	0.000	0.446	0.554
K51.0 Ulcerative (chronic) enterocolitis	0.552	0.448	0.000
G37.5 Concentric sclerosis [Balo]	0.549	0.451	0.000
G37.4 Subacute necrotising myelitis	0.549	0.451	0.000
G37.2 Central pontine myelinolysis	0.549	0.451	0.000
G37.1 Central demyelination of corpus callosum	0.549	0.451	0.000
G37.0 Diffuse sclerosis	0.549	0.451	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.453	0.547
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.453	0.547
E26.9 Hyperaldosteronism, unspecified	0.000	0.453	0.547
E25.9 Adrenogenital disorder, unspecified	0.000	0.460	0.540
E25.8 Other adrenogenital disorders	0.000	0.460	0.540
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.466	0.534
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.466	0.534
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.466	0.534
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.466	0.534
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.466	0.534
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.466	0.534
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.466	0.534
E24.8 Other Cushing's syndrome	0.000	0.471	0.529
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.471	0.529
E24.3 Ectopic ACTH syndrome	0.000	0.471	0.529
E24.1 Nelson's syndrome	0.000	0.471	0.529
M05.2 Rheumatoid vasculitis	0.000	0.471	0.528
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.474	0.525
E29.1 Testicular hypofunction	0.000	0.483	0.517
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.483	0.517
E00 Congenital iodine-deficiency syndrome	0.000	0.483	0.517
E12.9 Without complications	0.000	0.486	0.514
E12.8 With unspecified complications	0.000	0.486	0.514
E12.7 With multiple complications	0.000	0.486	0.514
E12.6 With other specified complications	0.000	0.486	0.514
E12.5 With peripheral circulatory complications	0.000	0.486	0.514
E12.4 With neurological complications	0.000	0.486	0.514
E12.3 With ophthalmic complications	0.000	0.486	0.514
E12.2 With renal complications	0.000	0.486	0.514
E12.1 With ketoacidosis	0.000	0.486	0.514
E12.0 With coma	0.000	0.486	0.514
E26.8 Other hyperaldosteronism	0.000	0.486	0.514
E26.1 Secondary hyperaldosteronism	0.000	0.486	0.514
G37.8 Other specified demyelinating diseases of central nervous system	0.513	0.487	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.488	0.512
E30.9 Disorder of puberty, unspecified	0.000	0.488	0.512
E30.8 Other disorders of puberty	0.000	0.488	0.512
E30.1 Precocious puberty	0.000	0.488	0.512
E30.0 Delayed puberty	0.000	0.488	0.512
E31.9 Polyglandular dysfunction, unspecified	0.000	0.488	0.512
E31.8 Other polyglandular dysfunction	0.000	0.488	0.512
E31.1 Polyglandular hyperfunction	0.000	0.488	0.512
E31.0 Autoimmune polyglandular failure	0.000	0.488	0.512
E32.9 Disease of thymus, unspecified	0.000	0.488	0.512
E32.8 Other diseases of thymus	0.000	0.488	0.512
E32.1 Abscess of thymus	0.000	0.488	0.512
E32.0 Persistent hyperplasia of thymus	0.000	0.488	0.512
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.488	0.512
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.488	0.512
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.488	0.512
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.488	0.511
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.489	0.511
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.489	0.511
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.489	0.511
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.489	0.511
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.489	0.511
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.489	0.511
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.489	0.511
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.489	0.511
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.489	0.511
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.490	0.510
M06.18 Adult-onset Still's disease (Other)	0.000	0.490	0.510
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.490	0.510
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.490	0.510
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.490	0.510
M06.14 Adult-onset Still's disease (Hand)	0.000	0.490	0.510
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.490	0.510
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.490	0.510
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.490	0.510
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.490	0.510
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.490	0.510
M06.28 Rheumatoid bursitis (Other)	0.000	0.490	0.510
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.490	0.510
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.490	0.510
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.490	0.510
M06.24 Rheumatoid bursitis (Hand)	0.000	0.490	0.510
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.490	0.510
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.490	0.510
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.490	0.510
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.490	0.510
E07 Other disorders of thyroid	0.000	0.490	0.510
E05.5 Thyroid crisis or storm	0.000	0.490	0.509
E05.4 Thyrotoxicosis factitia	0.000	0.490	0.509
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.490	0.509
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.490	0.509
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.494	0.506
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.494	0.506
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.494	0.506
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.494	0.506
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.494	0.506
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.494	0.506
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.494	0.506
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.494	0.506
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.494	0.506
E20.8 Other hypoparathyroidism	0.000	0.495	0.505
E20.1 Pseudohypoparathyroidism	0.000	0.495	0.505
E20.0 Idiopathic hypoparathyroidism	0.000	0.495	0.505
M12.2 Villonodular synovitis (pigmented)	0.000	0.499	0.501
E29.8 Other testicular dysfunction	0.000	0.503	0.497
E29.0 Testicular hyperfunction	0.000	0.503	0.497
M12.3 Palindromic rheumatism	0.000	0.503	0.496
E20.9 Hypoparathyroidism, unspecified	0.000	0.505	0.495
E65-E68 Obesity and other hyperalimentation	0.000	0.508	0.492
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.508	0.491
M12.5 Traumatic arthropathy	0.000	0.508	0.491
M12.4 Intermittent hydrarthrosis	0.000	0.508	0.491
M12.1 Kaschin-Beck disease	0.000	0.508	0.491
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.508	0.491
E13.8 With unspecified complications	0.000	0.509	0.491
E13.7 With multiple complications	0.000	0.509	0.491
E13.6 With other specified complications	0.000	0.509	0.491
E13.5 With peripheral circulatory complications	0.000	0.509	0.491
E13.4 With neurological complications	0.000	0.509	0.491
E13.2 With renal complications	0.000	0.509	0.491
E13.1 With ketoacidosis	0.000	0.509	0.491
E13.0 With coma	0.000	0.509	0.491
E13.9 Without complications	0.000	0.515	0.484
M11 Other crystal arthropathies	0.000	0.517	0.483
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.517	0.482
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.517	0.482
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.517	0.482
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.517	0.482
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.517	0.482
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.000	0.519	0.481
M09.2 Juvenile arthritis in ulcerative colitis	0.000	0.519	0.481
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.000	0.519	0.481
M09.0 Juvenile arthritis in psoriasis	0.000	0.519	0.481
E26.0 Primary hyperaldosteronism	0.000	0.523	0.477
M05.09 Felty's syndrome (Site unspecified)	0.000	0.524	0.476
M05.08 Felty's syndrome (Other)	0.000	0.524	0.476
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.524	0.476
M05.06 Felty's syndrome (Lower leg)	0.000	0.524	0.476
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.524	0.476
M05.04 Felty's syndrome (Hand)	0.000	0.524	0.476
M05.03 Felty's syndrome (Forearm)	0.000	0.524	0.476
M05.02 Felty's syndrome (Upper arm)	0.000	0.524	0.476
M05.01 Felty's syndrome (Shoulder region)	0.000	0.524	0.476
M05.00 Felty's syndrome (Multiple sites)	0.000	0.524	0.476
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.524	0.476
M05.18 Rheumatoid lung disease (Other)	0.000	0.524	0.476
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.524	0.476
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.524	0.476
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.524	0.476
M05.14 Rheumatoid lung disease (Hand)	0.000	0.524	0.476
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.524	0.476
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.524	0.476
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.524	0.476
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.524	0.476
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.524	0.476
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.524	0.476
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.524	0.476
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.524	0.476
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.524	0.476
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.524	0.476
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.524	0.476
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.524	0.476
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.524	0.476
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.524	0.476
M10 Gout	0.000	0.526	0.473
M08.9 Juvenile arthritis, unspecified	0.000	0.527	0.473
M08.8 Other juvenile arthritis	0.000	0.527	0.473
M08.4 Pauciarticular juvenile arthritis	0.000	0.527	0.473
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.527	0.473
M08.2 Juvenile arthritis with systemic onset	0.000	0.527	0.473
M08.1 Juvenile ankylosing spondylitis	0.000	0.527	0.473
E13.3 With ophthalmic complications	0.000	0.535	0.465
M08.0 Juvenile rheumatoid arthritis	0.000	0.537	0.463
I11 Hypertensive heart disease	0.000	0.539	0.461
M14.8 Arthropathies in other specified diseases classified elsewhere	0.000	0.543	0.457
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.000	0.543	0.457
M14.4 Arthropathy in amyloidosis	0.000	0.543	0.457
M14.3 Lipoid dermatoarthritis	0.000	0.543	0.457
M14.1 Crystal arthropathy in other metabolic disorders	0.000	0.543	0.457
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.000	0.543	0.457
M14.2 Diabetic arthropathy	0.000	0.547	0.453
E29.9 Testicular dysfunction, unspecified	0.000	0.550	0.450
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.000	0.550	0.450
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.000	0.550	0.450
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.000	0.550	0.450
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.000	0.550	0.450
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.000	0.550	0.450
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.000	0.550	0.450
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.000	0.550	0.450
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.000	0.550	0.450
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.000	0.550	0.450
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.000	0.550	0.450
M07.19 Arthritis mutilans (Site unspecified)	0.000	0.550	0.450
M07.18 Arthritis mutilans (Other)	0.000	0.550	0.450
M07.17 Arthritis mutilans (Ankle and foot)	0.000	0.550	0.450
M07.16 Arthritis mutilans (Lower leg)	0.000	0.550	0.450
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.000	0.550	0.450
M07.14 Arthritis mutilans (Hand)	0.000	0.550	0.450
M07.13 Arthritis mutilans (Forearm)	0.000	0.550	0.450
M07.12 Arthritis mutilans (Upper arm)	0.000	0.550	0.450
M07.11 Arthritis mutilans (Shoulder region)	0.000	0.550	0.450
M07.10 Arthritis mutilans (Multiple sites)	0.000	0.550	0.450
M07.29 Psoriatic spondylitis (Site unspecified)	0.000	0.550	0.450
M07.28 Psoriatic spondylitis (Other)	0.000	0.550	0.450
M07.27 Psoriatic spondylitis (Ankle and foot)	0.000	0.550	0.450
M07.26 Psoriatic spondylitis (Lower leg)	0.000	0.550	0.450
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.000	0.550	0.450
M07.24 Psoriatic spondylitis (Hand)	0.000	0.550	0.450
M07.23 Psoriatic spondylitis (Forearm)	0.000	0.550	0.450
M07.22 Psoriatic spondylitis (Upper arm)	0.000	0.550	0.450
M07.21 Psoriatic spondylitis (Shoulder region)	0.000	0.550	0.450
M07.20 Psoriatic spondylitis (Multiple sites)	0.000	0.550	0.450
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.000	0.550	0.450
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.000	0.550	0.450
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.000	0.550	0.450
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.000	0.550	0.450
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.000	0.550	0.450
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.000	0.550	0.450
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.000	0.550	0.450
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.000	0.550	0.450
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.000	0.550	0.450
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.000	0.550	0.450
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.000	0.550	0.450
M07.58 Arthropathy in ulcerative colitis (Other)	0.000	0.550	0.450
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.000	0.550	0.450
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.000	0.550	0.450
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.000	0.550	0.450
M07.54 Arthropathy in ulcerative colitis (Hand)	0.000	0.550	0.450
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.000	0.550	0.450
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.000	0.550	0.450
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.000	0.550	0.450
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.000	0.550	0.450
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.551	0.449
G36.0 Neuromyelitis optica [Devic]	0.437	0.563	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.564	0.436
E07.8 Other specified disorders of thyroid	0.000	0.564	0.436
H36 Retinal disorders in diseases classified elsewhere	0.000	0.564	0.436
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.567	0.433
E45 Retarded development following protein-energy malnutrition	0.000	0.567	0.433
E43 Unspecified severe protein-energy malnutrition	0.000	0.567	0.433
E42 Marasmic kwashiorkor	0.000	0.567	0.433
E41 Nutritional marasmus	0.000	0.567	0.433
E40 Kwashiorkor	0.000	0.567	0.433
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.569	0.430
E05.8 Other thyrotoxicosis	0.000	0.572	0.427
M14.6 Neuropathic arthropathy	0.000	0.573	0.427
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.573	0.426
I15.0 Renovascular hypertension	0.000	0.576	0.424
G36.9 Acute disseminated demyelination, unspecified	0.424	0.576	0.000
G36.8 Other specified acute disseminated demyelination	0.424	0.576	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.424	0.576	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.577	0.423
I15.2 Hypertension secondary to endocrine disorders	0.000	0.580	0.420
M07.68 Other enteropathic arthropathies (Other)	0.000	0.580	0.419
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.000	0.580	0.419
M07.66 Other enteropathic arthropathies (Lower leg)	0.000	0.580	0.419
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.000	0.580	0.419
M07.64 Other enteropathic arthropathies (Hand)	0.000	0.580	0.419
M07.63 Other enteropathic arthropathies (Forearm)	0.000	0.580	0.419
M07.62 Other enteropathic arthropathies (Upper arm)	0.000	0.580	0.419
M07.61 Other enteropathic arthropathies (Shoulder region)	0.000	0.580	0.419
M07.60 Other enteropathic arthropathies (Multiple sites)	0.000	0.580	0.419
E34.5 Androgen resistance syndrome	0.000	0.588	0.412
E34.4 Constitutional tall stature	0.000	0.588	0.412
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.588	0.412
E34.1 Other hypersecretion of intestinal hormones	0.000	0.588	0.412
E06 Thyroiditis	0.000	0.589	0.411
E34.9 Endocrine disorder, unspecified	0.000	0.600	0.400
E50-E64 Other nutritional deficiencies	0.000	0.602	0.398
M13 Other arthritis	0.000	0.603	0.397
E34.8 Other specified endocrine disorders	0.000	0.607	0.393
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.608	0.391
M12.39 Palindromic rheumatism (Site unspecified)	0.000	0.610	0.390
I15.1 Hypertension secondary to other renal disorders	0.000	0.611	0.389
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.616	0.384
I15.8 Other secondary hypertension	0.000	0.618	0.382
M05.28 Rheumatoid vasculitis (Other)	0.000	0.621	0.379
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.621	0.379
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.621	0.379
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.621	0.379
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.621	0.379
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.621	0.379
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.621	0.379
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.621	0.379
M12.24 Villonodular synovitis (pigmented) (Hand)	0.000	0.622	0.378
K90 Intestinal malabsorption	0.000	0.622	0.378
M07.69 Other enteropathic arthropathies (Site unspecified)	0.000	0.623	0.376
E34.0 Carcinoid syndrome	0.000	0.624	0.376
I13 Hypertensive heart and renal disease	0.000	0.624	0.375
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.629	0.370
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.629	0.370
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.629	0.370
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.629	0.370
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.629	0.370
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.629	0.370
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.629	0.370
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.629	0.370

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations