TreeWAS – Variant ID: rs2523632

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	1.000
E03 Other hypothyroidism	0.000	1.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	1.000
# Top node	0.001	0.999
L40-L45 Papulosquamous disorders	0.003	0.997
L40 Psoriasis	0.003	0.997
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.005	0.995
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.005	0.995
E65-E68 Obesity and other hyperalimentation	0.008	0.992
L57 Skin changes due to chronic exposure to nonionising radiation	0.009	0.991
L40.5 Arthropathic psoriasis	0.012	0.988
M06.9 Rheumatoid arthritis, unspecified	0.012	0.988
L40.9 Psoriasis, unspecified	0.013	0.987
E66 Obesity	0.014	0.986
M06 Other rheumatoid arthritis	0.015	0.985
M05-M14 Inflammatory polyarthropathies	0.016	0.984
E66.8 Other obesity	0.016	0.984
D50-D53 Nutritional anaemias	0.017	0.983
L57.0 Actinic keratosis	0.017	0.983
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.019	0.981
D50 Iron deficiency anaemia	0.021	0.979
Chapter I Certain infectious and parasitic diseases	0.022	0.978
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.022	0.978
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.024	0.976
D50.9 Iron deficiency anaemia, unspecified	0.025	0.975
L00-L08 Infections of the skin and subcutaneous tissue	0.027	0.973
B35-B49 Mycoses	0.029	0.971
B37 Candidiasis	0.031	0.969
B37.8 Candidiasis of other sites	0.034	0.966
L02 Cutaneous abscess, furuncle and carbuncle	0.041	0.959
Chapter VIII Diseases of the ear and mastoid process	0.042	0.958
E70-E90 Metabolic disorders	0.043	0.957
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.049	0.951
H65-H75 Diseases of middle ear and mastoid	0.072	0.928
B25-B34 Other viral diseases	0.074	0.926
B37.0 Candidal stomatitis	0.083	0.917
H72 Perforation of tympanic membrane	0.087	0.913
L20-L30 Dermatitis and eczema	0.088	0.912
E06 Thyroiditis	0.092	0.908
H72.9 Perforation of tympanic membrane, unspecified	0.096	0.904
M07 Psoriatic and enteropathic arthropathies	0.099	0.901
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.101	0.899
M45-M49 Spondylopathies	0.101	0.899
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.112	0.888
M45 Ankylosing spondylitis	0.113	0.887
E10-E14 Diabetes mellitus	0.117	0.883
B34 Viral infection of unspecified site	0.117	0.883
Chapter V Mental and behavioural disorders	0.121	0.879
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.121	0.879
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.125	0.875
M45.X9 Ankylosing spondylitis (Site unspecified)	0.128	0.872
E05 Thyrotoxicosis [hyperthyroidism]	0.135	0.865
E10 Insulin-dependent diabetes mellitus	0.146	0.854
M05 Seropositive rheumatoid arthritis	0.152	0.848
H65 Nonsuppurative otitis media	0.157	0.843
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.158	0.842
M07.3 Other psoriatic arthropathies	0.159	0.841
H80-H83 Diseases of inner ear	0.160	0.840
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.161	0.839
B34.9 Viral infection, unspecified	0.164	0.836
E87 Other disorders of fluid, electrolyte and acid-base balance	0.166	0.834
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.168	0.832
E06.3 Autoimmune thyroiditis	0.169	0.831
D80-D89 Certain disorders involving the immune mechanism	0.169	0.831
E89.0 Postprocedural hypothyroidism	0.175	0.825
L29 Pruritus	0.178	0.822
M35 Other systemic involvement of connective tissue	0.184	0.816
L08 Other local infections of skin and subcutaneous tissue	0.186	0.814
M35.3 Polymyalgia rheumatica	0.186	0.814
M20-M25 Other joint disorders	0.186	0.814
B20-B24 Human immunodeficiency virus [HIV] disease	0.187	0.813
D68 Other coagulation defects	0.187	0.813
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.189	0.811
M95.0 Acquired deformity of nose	0.190	0.810
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.193	0.807
E20-E35 Disorders of other endocrine glands	0.201	0.799
E86 Volume depletion	0.210	0.790
M06.0 Seronegative rheumatoid arthritis	0.211	0.789
B35 Dermatophytosis	0.211	0.789
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.212	0.788
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.213	0.786
L29.0 Pruritus ani	0.220	0.780
E05.0 Thyrotoxicosis with diffuse goitre	0.228	0.772
B99-B99 Other infectious diseases	0.228	0.772
E87.1 Hypo-osmolality and hyponatraemia	0.230	0.770
D86 Sarcoidosis	0.234	0.766
E27 Other disorders of adrenal gland	0.235	0.765
M07.30 Other psoriatic arthropathies (Multiple sites)	0.236	0.764
A50-A64 Infections with a predominantly sexual mode of transmission	0.239	0.761
D55-D59 Haemolytic anaemias	0.240	0.760
H72.0 Central perforation of tympanic membrane	0.244	0.756
E73 Lactose intolerance	0.245	0.755
E10.9 Without complications	0.246	0.754
M05.9 Seropositive rheumatoid arthritis, unspecified	0.249	0.751
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.249	0.751
E10.3 With ophthalmic complications	0.250	0.750
H80 Otosclerosis	0.253	0.747
E66.0 Obesity due to excess calories	0.253	0.747
M00-M03 Infectious arthropathies	0.254	0.746
E88 Other metabolic disorders	0.255	0.745
L56 Other acute skin changes due to ultraviolet radiation	0.257	0.743
E27.1 Primary adrenocortical insufficiency	0.261	0.739
H65.9 Nonsuppurative otitis media, unspecified	0.262	0.738
F40-F48 Neurotic, stress-related and somatoform disorders	0.267	0.733
Chapter XXII Codes for special purposes	0.268	0.732
B34.8 Other viral infections of unspecified site	0.270	0.729
L30 Other dermatitis	0.274	0.726
F00-F09 Organic, including symptomatic, mental disorders	0.275	0.725
L05 Pilonidal cyst	0.278	0.722
F30-F39 Mood [affective] disorders	0.278	0.722
E87.2 Acidosis	0.279	0.721
E65 Localised adiposity	0.280	0.720
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.280	0.720
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.283	0.717
E03.5 Myxoedema coma	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.283	0.717
Chapter XVI Certain conditions originating in the perinatal period	0.283	0.716
M35.0 Sicca syndrome [Sjogren]	0.283	0.716
L44 Other papulosquamous disorders	0.285	0.715
L41 Parapsoriasis	0.285	0.715
L45 Papulosquamous disorders in diseases classified elsewhere	0.285	0.715
L40.8 Other psoriasis	0.285	0.715
L40.4 Guttate psoriasis	0.285	0.715
L40.3 Pustulosis palmaris et plantaris	0.285	0.715
L40.2 Acrodermatitis continua	0.285	0.715
L40.1 Generalised pustular psoriasis	0.285	0.715
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.287	0.713
L58 Radiodermatitis	0.287	0.713
L55 Sunburn	0.287	0.713
E67 Other hyperalimentation	0.289	0.711
E68 Sequelae of hyperalimentation	0.289	0.711
E80 Disorders of porphyrin and bilirubin metabolism	0.289	0.711
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.290	0.710
L57.5 Actinic granuloma	0.290	0.710
L57.3 Poikiloderma of Civatte	0.290	0.710
L57.2 Cutis rhomboidalis nuchae	0.290	0.710
L57.1 Actinic reticuloid	0.290	0.710
M07.39 Other psoriatic arthropathies (Site unspecified)	0.290	0.710
M06.98 Rheumatoid arthritis, unspecified (Other)	0.292	0.708
E66.1 Drug-induced obesity	0.293	0.707
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.293	0.707
M14 Arthropathies in other diseases classified elsewhere	0.293	0.707
M06.8 Other specified rheumatoid arthritis	0.294	0.706
M06.2 Rheumatoid bursitis	0.294	0.706
M06.1 Adult-onset Still's disease	0.294	0.706
L27 Dermatitis due to substances taken internally	0.294	0.706
M12 Other specific arthropathies	0.294	0.705
M09 Juvenile arthritis in diseases classified elsewhere	0.294	0.705
M08 Juvenile arthritis	0.294	0.705
E10.1 With ketoacidosis	0.295	0.705
D68.5 Primary Thrombophilia	0.295	0.705
F80-F89 Disorders of psychological development	0.296	0.704
D50.1 Sideropenic dysphagia	0.298	0.702
E50-E64 Other nutritional deficiencies	0.298	0.702
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.299	0.701
A75-A79 Rickettsioses	0.299	0.701
A70-A74 Other diseases caused by chlamydiae	0.299	0.701
A65-A69 Other spirochaetal diseases	0.299	0.701
A20-A28 Certain zoonotic bacterial diseases	0.299	0.701
D86.9 Sarcoidosis, unspecified	0.300	0.700
B25 Cytomegaloviral disease	0.301	0.699
L04 Acute lymphadenitis	0.302	0.698
L01 Impetigo	0.302	0.698
L00 Staphylococcal scalded skin syndrome	0.302	0.698
H73 Other disorders of tympanic membrane	0.303	0.697
M34 Systemic sclerosis	0.303	0.697
B48 Other mycoses, not elsewhere classified	0.304	0.696
B47 Mycetoma	0.304	0.696
B46 Zygomycosis	0.304	0.696
B45 Cryptococcosis	0.304	0.696
B43 Chromomycosis and phaeomycotic abscess	0.304	0.696
B42 Sporotrichosis	0.304	0.696
B41 Paracoccidioidomycosis	0.304	0.696
B40 Blastomycosis	0.304	0.696
B39 Histoplasmosis	0.304	0.696
B38 Coccidioidomycosis	0.304	0.696
B36 Other superficial mycoses	0.304	0.696
E74 Other disorders of carbohydrate metabolism	0.305	0.695
B24 Unspecified human immunodeficiency virus [HIV] disease	0.305	0.695
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.305	0.695
B37.7 Candidal septicaemia	0.305	0.695
B37.6 Candidal endocarditis	0.305	0.695
B37.5 Candidal meningitis	0.305	0.695
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.306	0.694
E03.8 Other specified hypothyroidism	0.311	0.689
E06.9 Thyroiditis, unspecified	0.312	0.688
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.312	0.688
E84 Cystic fibrosis	0.314	0.686
E79 Disorders of purine and pyrimidine metabolism	0.314	0.686
E77 Disorders of glycoprotein metabolism	0.314	0.686
E76 Disorders of glycosaminoglycan metabolism	0.314	0.686
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.314	0.686
E72 Other disorders of amino-acid metabolism	0.314	0.686
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.314	0.686
E70 Disorders of aromatic amino-acid metabolism	0.314	0.686
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.314	0.686
D68.9 Coagulation defect, unspecified	0.315	0.685
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.316	0.684
F60-F69 Disorders of adult personality and behaviour	0.317	0.683
A15-A19 Tuberculosis	0.317	0.683
E14 Unspecified diabetes mellitus	0.318	0.682
L57.4 Cutis laxa senilis	0.319	0.681
H80.9 Otosclerosis, unspecified	0.319	0.681
L10-L14 Bullous disorders	0.323	0.677
M46 Other inflammatory spondylopathies	0.323	0.676
H83 Other diseases of inner ear	0.325	0.675
H60-H62 Diseases of external ear	0.327	0.673
B50-B64 Protozoal diseases	0.327	0.673
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.331	0.669
E40-E46 Malnutrition	0.332	0.668
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.332	0.668
M35.7 Hypermobility syndrome	0.332	0.668
D60-D64 Aplastic and other anaemias	0.333	0.667
E10.2 With renal complications	0.334	0.666
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.335	0.665
H68 Eustachian salpingitis and obstruction	0.335	0.665
H67 Otitis media in diseases classified elsewhere	0.335	0.665
B33 Other viral diseases, not elsewhere classified	0.336	0.664
B30 Viral conjunctivitis	0.336	0.664
B27 Infectious mononucleosis	0.336	0.664
B26 Mumps	0.336	0.664
H70 Mastoiditis and related conditions	0.337	0.663
E10.5 With peripheral circulatory complications	0.337	0.663
H65.2 Chronic serous otitis media	0.338	0.662
L28 Lichen simplex chronicus and prurigo	0.338	0.662
B37.1 Pulmonary candidiasis	0.339	0.661
F31 Bipolar affective disorder	0.339	0.661
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.339	0.661
M11 Other crystal arthropathies	0.340	0.660
B15-B19 Viral hepatitis	0.340	0.660
H72.1 Attic perforation of tympanic membrane	0.345	0.655
E66.2 Extreme obesity with alveolar hypoventilation	0.346	0.654
L24 Irritant contact dermatitis	0.346	0.654
L21 Seborrhoeic dermatitis	0.346	0.654
L26 Exfoliative dermatitis	0.346	0.654
L22 Diaper [napkin] dermatitis	0.346	0.654
D86.0 Sarcoidosis of lung	0.347	0.653
H65.4 Other chronic nonsuppurative otitis media	0.348	0.652
B37.9 Candidiasis, unspecified	0.349	0.651
E06.5 Other chronic thyroiditis	0.349	0.651
E06.4 Drug-induced thyroiditis	0.349	0.651
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.349	0.651
E06.1 Subacute thyroiditis	0.349	0.651
E06.0 Acute thyroiditis	0.349	0.651
F42 Obsessive-compulsive disorder	0.349	0.651
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.350	0.649
B35.1 Tinea unguium	0.351	0.649
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.351	0.649
M07.6 Other enteropathic arthropathies	0.354	0.646
M07.5 Arthropathy in ulcerative colitis	0.354	0.646
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.354	0.646
M07.2 Psoriatic spondylitis	0.354	0.646
M07.1 Arthritis mutilans	0.354	0.646
M07.0 Distal interphalangeal psoriatic arthropathy	0.354	0.646
D52 Folate deficiency anaemia	0.354	0.646
M06.4 Inflammatory polyarthropathy	0.354	0.646
L20 Atopic dermatitis	0.354	0.646
B90-B94 Sequelae of infectious and parasitic diseases	0.354	0.645
E05.9 Thyrotoxicosis, unspecified	0.356	0.644
B37.4 Candidiasis of other urogenital sites	0.358	0.642
E10.4 With neurological complications	0.359	0.641
E85 Amyloidosis	0.361	0.639
D66 Hereditary factor VIII deficiency	0.362	0.638
B65-B83 Helminthiases	0.363	0.637
D51 Vitamin B12 deficiency anaemia	0.363	0.637
D67 Hereditary factor IX deficiency	0.363	0.637
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.363	0.637
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.364	0.636
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.364	0.636
M45.X6 Ankylosing spondylitis (Lumbar region)	0.364	0.636
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.364	0.636
M45.X4 Ankylosing spondylitis (Thoracic region)	0.364	0.636
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.364	0.636
M45.X2 Ankylosing spondylitis (Cervical region)	0.364	0.636
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.364	0.636
L25 Unspecified contact dermatitis	0.364	0.635
B85-B89 Pediculosis, acariasis and other infestations	0.365	0.635
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.365	0.635
E12 Malnutrition-related diabetes mellitus	0.367	0.633
E22 Hyperfunction of pituitary gland	0.367	0.633
B34.3 Parvovirus infection, unspecified	0.367	0.633
B34.2 Coronavirus infection, unspecified	0.367	0.633
B34.1 Enterovirus infection, unspecified	0.367	0.633
B34.0 Adenovirus infection, unspecified	0.367	0.633
M06.3 Rheumatoid nodule	0.367	0.633
E87.7 Fluid overload	0.369	0.631
D69 Purpura and other haemorrhagic conditions	0.369	0.631
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.370	0.630
M99 Biomechanical lesions, not elsewhere classified	0.370	0.630
B37.2 Candidiasis of skin and nail	0.371	0.628
D50.8 Other iron deficiency anaemias	0.372	0.628
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.373	0.627
E89.8 Other postprocedural endocrine and metabolic disorders	0.373	0.627
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.373	0.627
E89.5 Postprocedural testicular hypofunction	0.373	0.627
E89.4 Postprocedural ovarian failure	0.373	0.627
E89.1 Postprocedural hypoinsulinaemia	0.373	0.627
E07 Other disorders of thyroid	0.373	0.627
M49 Spondylopathies in diseases classified elsewhere	0.373	0.626
F43 Reaction to severe stress, and adjustment disorders	0.375	0.625
M91-M94 Chondropathies	0.375	0.625
B99 Other and unspecified infectious diseases	0.376	0.624
D68.0 Von Willebrand's disease	0.377	0.623
M60-M63 Disorders of muscles	0.377	0.623
E05.5 Thyroid crisis or storm	0.380	0.620
E05.4 Thyrotoxicosis factitia	0.380	0.620
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.380	0.620
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.380	0.620
D70-D77 Other diseases of blood and blood-forming organs	0.380	0.620
D59 Acquired haemolytic anaemia	0.381	0.618
L23 Allergic contact dermatitis	0.381	0.618
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.382	0.618
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.383	0.617
L05.0 Pilonidal cyst with abscess	0.383	0.617
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.383	0.617
E89.3 Postprocedural hypopituitarism	0.384	0.615
H65.3 Chronic mucoid otitis media	0.386	0.614
E10.0 With coma	0.387	0.613
E10.7 With multiple complications	0.388	0.612
B34.4 Papovirus infection, unspecified	0.388	0.612
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.388	0.612
F70-F79 Mental retardation	0.389	0.611
E73.9 Lactose intolerance, unspecified	0.390	0.610
M05.8 Other seropositive rheumatoid arthritis	0.392	0.608
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.392	0.608
M05.2 Rheumatoid vasculitis	0.392	0.608
M05.1 Rheumatoid lung disease	0.392	0.608
M05.0 Felty's syndrome	0.392	0.608
L29.8 Other pruritus	0.395	0.605
H65.1 Other acute nonsuppurative otitis media	0.396	0.604
H65.0 Acute serous otitis media	0.396	0.604
L29.9 Pruritus, unspecified	0.397	0.603
M07.38 Other psoriatic arthropathies (Other)	0.397	0.603
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.397	0.603
M07.36 Other psoriatic arthropathies (Lower leg)	0.397	0.603
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.397	0.603
M07.34 Other psoriatic arthropathies (Hand)	0.397	0.603
M07.33 Other psoriatic arthropathies (Forearm)	0.397	0.603
M07.32 Other psoriatic arthropathies (Upper arm)	0.397	0.603
M07.31 Other psoriatic arthropathies (Shoulder region)	0.397	0.603
H82 Vertiginous syndromes in diseases classified elsewhere	0.398	0.602
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.399	0.601
M95.8 Other specified acquired deformities of musculoskeletal system	0.399	0.601
M95.5 Acquired deformity of pelvis	0.399	0.601
M95.4 Acquired deformity of chest and rib	0.399	0.601
M95.3 Acquired deformity of neck	0.399	0.601
M95.2 Other acquired deformity of head	0.399	0.601
M95.1 Cauliflower ear	0.399	0.601
E27.4 Other and unspecified adrenocortical insufficiency	0.400	0.600
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.400	0.600
E87.4 Mixed disorder of acid-base balance	0.402	0.598
F81 Specific developmental disorders of scholastic skills	0.402	0.598
D53 Other nutritional anaemias	0.403	0.596
H69 Other disorders of Eustachian tube	0.403	0.596
D84 Other immunodeficiencies	0.404	0.596
D83 Common variable immunodeficiency	0.404	0.596
D82 Immunodeficiency associated with other major defects	0.404	0.596
D81 Combined immunodeficiencies	0.404	0.596
E89.2 Postprocedural hypoparathyroidism	0.405	0.595
L08.8 Other specified local infections of skin and subcutaneous tissue	0.405	0.595
R21 Rash and other nonspecific skin eruption	0.405	0.595
D68.2 Hereditary deficiency of other clotting factors	0.406	0.594
L30.8 Other specified dermatitis	0.406	0.593
F42.9 Obsessive-compulsive disorder, unspecified	0.408	0.592
F40 Phobic anxiety disorders	0.409	0.591
M30 Polyarteritis nodosa and related conditions	0.409	0.591
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.410	0.590
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.410	0.590
M34.9 Systemic sclerosis, unspecified	0.410	0.590
L42 Pityriasis rosea	0.411	0.589
L29.3 Anogenital pruritus, unspecified	0.411	0.589
L29.1 Pruritus scroti	0.411	0.589
E14.9 Without complications	0.411	0.589
M35.9 Systemic involvement of connective tissue, unspecified	0.415	0.585
M35.8 Other specified systemic involvement of connective tissue	0.415	0.585
M35.6 Relapsing panniculitis [Weber-Christian]	0.415	0.585
M35.5 Multifocal fibrosclerosis	0.415	0.585
M35.4 Diffuse (eosinophilic) fasciitis	0.415	0.585
M35.2 Behcet's disease	0.415	0.585
M35.1 Other overlap syndromes	0.415	0.585
F05 Delirium, not induced by alcohol and other psychoactive substances	0.415	0.585
L08.1 Erythrasma	0.416	0.584
L08.0 Pyoderma	0.416	0.584
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.416	0.584
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.417	0.583
M32 Systemic lupus erythematosus	0.417	0.583
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions	0.417	0.583
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases	0.417	0.583
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms	0.417	0.583
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases	0.417	0.583
M22 Disorders of patella	0.417	0.583
D68.4 Acquired coagulation factor deficiency	0.417	0.583
D68.1 Hereditary factor XI deficiency	0.417	0.583
B35.3 Tinea pedis	0.420	0.580
M46.9 Inflammatory spondylopathy, unspecified	0.420	0.580
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.420	0.580
D64 Other anaemias	0.423	0.577
M00 Pyogenic arthritis	0.423	0.577
E83 Disorders of mineral metabolism	0.425	0.575
L27.0 Generalised skin eruption due to drugs and medicaments	0.425	0.575
E10.8 With unspecified complications	0.426	0.574
E35 Disorders of endocrine glands in diseases classified elsewhere	0.427	0.573
E32 Diseases of thymus	0.427	0.573
E31 Polyglandular dysfunction	0.427	0.573
E30 Disorders of puberty, not elsewhere classified	0.427	0.573
E25 Adrenogenital disorders	0.427	0.573
E20 Hypoparathyroidism	0.427	0.573
F99-F99 Unspecified mental disorder	0.428	0.571
F20 Schizophrenia	0.429	0.571
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.429	0.571
F30 Manic episode	0.429	0.571
H72.2 Other marginal perforations of tympanic membrane	0.431	0.569
L40.0 Psoriasis vulgaris	0.431	0.569
B37.3 Candidiasis of vulva and vagina	0.432	0.567
R26 Abnormalities of gait and mobility	0.433	0.567
M06.08 Seronegative rheumatoid arthritis (Other)	0.434	0.566
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.434	0.566
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.434	0.566
M06.04 Seronegative rheumatoid arthritis (Hand)	0.434	0.566
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.434	0.566
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.434	0.566
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.434	0.566
L43 Lichen planus	0.434	0.566
B35.9 Dermatophytosis, unspecified	0.434	0.566
B35.8 Other dermatophytoses	0.434	0.566
B35.6 Tinea cruris	0.434	0.566
B35.5 Tinea imbricata	0.434	0.566
B35.4 Tinea corporis	0.434	0.566
B35.2 Tinea manuum	0.434	0.566
B35.0 Tinea barbae and tinea capitis	0.434	0.566
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.437	0.563
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.441	0.559
H72.8 Other perforations of tympanic membrane	0.441	0.558
M10 Gout	0.442	0.558
A80-A89 Viral infections of the central nervous system	0.443	0.557
H83.0 Labyrinthitis	0.443	0.557
F22 Persistent delusional disorders	0.444	0.556
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.446	0.554
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.446	0.554
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.446	0.554
E26 Hyperaldosteronism	0.447	0.553
B95-B98 Bacterial, viral and other infectious agents	0.447	0.553
D68.6 Other Thrombophilia	0.450	0.550
B49 Unspecified mycosis	0.450	0.550
E10.6 With other specified complications	0.450	0.550
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.450	0.550
D86.3 Sarcoidosis of skin	0.450	0.549
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.450	0.549
D86.1 Sarcoidosis of lymph nodes	0.450	0.549
R26.8 Other and unspecified abnormalities of gait and mobility	0.451	0.549
E27.5 Adrenomedullary hyperfunction	0.452	0.548
E27.3 Drug-induced adrenocortical insufficiency	0.452	0.548
E27.2 Addisonian crisis	0.452	0.548
E27.0 Other adrenocortical overactivity	0.452	0.548
F60 Specific personality disorders	0.452	0.548
F00 Dementia in Alzheimer's disease	0.453	0.547
A59 Trichomoniasis	0.454	0.545
A56 Other sexually transmitted chlamydial diseases	0.454	0.545
A54 Gonococcal infection	0.454	0.545
A53 Other and unspecified syphilis	0.454	0.545
A52 Late syphilis	0.454	0.545
A51 Early syphilis	0.454	0.545
A50 Congenital syphilis	0.454	0.545
A64 Unspecified sexually transmitted disease	0.454	0.545
A58 Granuloma inguinale	0.454	0.545
A57 Chancroid	0.454	0.545
A55 Chlamydial lymphogranuloma (venereum)	0.454	0.545
D57 Sickle-cell disorders	0.455	0.545
D56 Thalassaemia	0.455	0.545
D55 Anaemia due to enzyme disorders	0.455	0.545
F25 Schizoaffective disorders	0.455	0.545
M13 Other arthritis	0.455	0.545
M34.1 CR(E)ST syndrome	0.456	0.544
R47-R49 Symptoms and signs involving speech and voice	0.457	0.543
M33 Dermatopolymyositis	0.457	0.543
Chapter IX Diseases of the circulatory system	0.458	0.542
E73.8 Other lactose intolerance	0.459	0.541
E73.1 Secondary lactase deficiency	0.459	0.541
E73.0 Congenital lactase deficiency	0.459	0.541
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.459	0.541
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.461	0.539
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.461	0.539
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.461	0.539
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.461	0.539
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.461	0.539
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.461	0.539
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.461	0.539
E87.5 Hyperkalaemia	0.463	0.537
B25.9 Cytomegaloviral disease, unspecified	0.463	0.537
E87.3 Alkalosis	0.464	0.536
L50-L54 Urticaria and erythema	0.464	0.536
H80.8 Other otosclerosis	0.464	0.536
H80.2 Cochlear otosclerosis	0.464	0.536

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations