TreeWAS – Variant ID: rs2523639

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	0.000	1.000
# Top node	0.000	0.001	0.999
L40-L45 Papulosquamous disorders	0.000	0.003	0.997
L40 Psoriasis	0.000	0.004	0.996
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.004	0.996
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.000	0.006	0.994
M06.9 Rheumatoid arthritis, unspecified	0.000	0.009	0.991
E65-E68 Obesity and other hyperalimentation	0.000	0.009	0.991
L57 Skin changes due to chronic exposure to nonionising radiation	0.000	0.011	0.989
M06 Other rheumatoid arthritis	0.000	0.012	0.988
L40.5 Arthropathic psoriasis	0.000	0.013	0.987
M05-M14 Inflammatory polyarthropathies	0.000	0.013	0.987
D50-D53 Nutritional anaemias	0.000	0.014	0.986
L40.9 Psoriasis, unspecified	0.000	0.014	0.986
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.000	0.016	0.984
E66 Obesity	0.000	0.016	0.984
D50 Iron deficiency anaemia	0.000	0.017	0.983
E66.8 Other obesity	0.000	0.018	0.982
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.019	0.981
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.020	0.980
L57.0 Actinic keratosis	0.000	0.020	0.980
D50.9 Iron deficiency anaemia, unspecified	0.000	0.020	0.980
Chapter I Certain infectious and parasitic diseases	0.000	0.032	0.968
L00-L08 Infections of the skin and subcutaneous tissue	0.000	0.034	0.966
B35-B49 Mycoses	0.000	0.042	0.958
Chapter VIII Diseases of the ear and mastoid process	0.000	0.044	0.956
B37 Candidiasis	0.000	0.045	0.955
B37.8 Candidiasis of other sites	0.000	0.049	0.951
E70-E90 Metabolic disorders	0.000	0.051	0.949
L02 Cutaneous abscess, furuncle and carbuncle	0.000	0.051	0.949
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.061	0.939
H65-H75 Diseases of middle ear and mastoid	0.000	0.076	0.924
B25-B34 Other viral diseases	0.000	0.079	0.921
L20-L30 Dermatitis and eczema	0.000	0.091	0.909
H72 Perforation of tympanic membrane	0.000	0.091	0.909
E06 Thyroiditis	0.000	0.094	0.906
M07 Psoriatic and enteropathic arthropathies	0.000	0.096	0.904
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.098	0.902
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.101	0.899
M45-M49 Spondylopathies	0.000	0.103	0.897
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.000	0.103	0.897
B37.0 Candidal stomatitis	0.000	0.106	0.894
E10-E14 Diabetes mellitus	0.000	0.108	0.892
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.000	0.109	0.891
M45 Ankylosing spondylitis	0.000	0.115	0.885
B34 Viral infection of unspecified site	0.000	0.117	0.883
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.131	0.869
E10 Insulin-dependent diabetes mellitus	0.000	0.131	0.869
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.136	0.864
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.139	0.861
M05 Seropositive rheumatoid arthritis	0.000	0.149	0.851
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.000	0.150	0.850
M07.3 Other psoriatic arthropathies	0.000	0.156	0.844
B34.9 Viral infection, unspecified	0.000	0.158	0.842
H80-H83 Diseases of inner ear	0.000	0.159	0.841
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.160	0.840
Chapter V Mental and behavioural disorders	0.000	0.160	0.840
H65 Nonsuppurative otitis media	0.000	0.164	0.836
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.167	0.833
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.167	0.833
E06.3 Autoimmune thyroiditis	0.000	0.172	0.828
D80-D89 Certain disorders involving the immune mechanism	0.000	0.172	0.828
D68 Other coagulation defects	0.000	0.177	0.823
M95.0 Acquired deformity of nose	0.000	0.179	0.821
M35 Other systemic involvement of connective tissue	0.000	0.186	0.814
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.187	0.813
M35.3 Polymyalgia rheumatica	0.000	0.188	0.812
L29 Pruritus	0.000	0.189	0.811
M20-M25 Other joint disorders	0.000	0.189	0.811
E89.0 Postprocedural hypothyroidism	0.000	0.192	0.808
L08 Other local infections of skin and subcutaneous tissue	0.000	0.193	0.807
B20-B24 Human immunodeficiency virus [HIV] disease	0.000	0.196	0.804
E86 Volume depletion	0.000	0.201	0.799
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.205	0.795
E10.9 Without complications	0.000	0.207	0.793
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.208	0.792
M06.0 Seronegative rheumatoid arthritis	0.000	0.210	0.790
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.211	0.789
E20-E35 Disorders of other endocrine glands	0.000	0.217	0.783
B35 Dermatophytosis	0.000	0.223	0.777
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.230	0.769
L29.0 Pruritus ani	0.000	0.231	0.769
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.234	0.766
B99-B99 Other infectious diseases	0.000	0.237	0.763
D86 Sarcoidosis	0.000	0.238	0.762
E10.3 With ophthalmic complications	0.000	0.240	0.760
D55-D59 Haemolytic anaemias	0.000	0.240	0.760
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.247	0.753
H72.0 Central perforation of tympanic membrane	0.000	0.249	0.751
M00-M03 Infectious arthropathies	0.000	0.251	0.749
E66.0 Obesity due to excess calories	0.000	0.251	0.749
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.252	0.748
E27 Other disorders of adrenal gland	0.000	0.252	0.748
H80 Otosclerosis	0.000	0.253	0.747
E73 Lactose intolerance	0.000	0.255	0.745
A50-A64 Infections with a predominantly sexual mode of transmission	0.000	0.257	0.743
L56 Other acute skin changes due to ultraviolet radiation	0.000	0.258	0.742
E88 Other metabolic disorders	0.000	0.263	0.737
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.269	0.731
B34.8 Other viral infections of unspecified site	0.000	0.271	0.729
Chapter XXII Codes for special purposes	0.000	0.274	0.726
E27.1 Primary adrenocortical insufficiency	0.000	0.277	0.723
L27 Dermatitis due to substances taken internally	0.000	0.277	0.723
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.279	0.721
L30 Other dermatitis	0.000	0.281	0.719
E65 Localised adiposity	0.000	0.281	0.718
L05 Pilonidal cyst	0.000	0.282	0.718
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
Chapter XVI Certain conditions originating in the perinatal period	0.000	0.284	0.716
E10.1 With ketoacidosis	0.000	0.284	0.716
L44 Other papulosquamous disorders	0.000	0.285	0.715
L41 Parapsoriasis	0.000	0.285	0.715
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.285	0.715
L40.8 Other psoriasis	0.000	0.285	0.714
L40.4 Guttate psoriasis	0.000	0.285	0.714
L40.3 Pustulosis palmaris et plantaris	0.000	0.285	0.714
L40.2 Acrodermatitis continua	0.000	0.285	0.714
L40.1 Generalised pustular psoriasis	0.000	0.285	0.714
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.287	0.713
D68.5 Primary Thrombophilia	0.000	0.287	0.713
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.000	0.287	0.712
L58 Radiodermatitis	0.000	0.287	0.712
L55 Sunburn	0.000	0.287	0.712
M35.0 Sicca syndrome [Sjogren]	0.000	0.288	0.712
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.290	0.710
E67 Other hyperalimentation	0.000	0.290	0.710
E68 Sequelae of hyperalimentation	0.000	0.290	0.710
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.000	0.290	0.710
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.000	0.291	0.709
L57.5 Actinic granuloma	0.000	0.291	0.709
L57.3 Poikiloderma of Civatte	0.000	0.291	0.709
L57.2 Cutis rhomboidalis nuchae	0.000	0.291	0.709
L57.1 Actinic reticuloid	0.000	0.291	0.709
M06.8 Other specified rheumatoid arthritis	0.000	0.291	0.708
M06.2 Rheumatoid bursitis	0.000	0.291	0.708
M06.1 Adult-onset Still's disease	0.000	0.291	0.708
M14 Arthropathies in other diseases classified elsewhere	0.000	0.292	0.708
M12 Other specific arthropathies	0.000	0.292	0.707
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.292	0.707
M08 Juvenile arthritis	0.000	0.292	0.707
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.294	0.705
E66.1 Drug-induced obesity	0.000	0.295	0.705
D50.1 Sideropenic dysphagia	0.000	0.295	0.705
D86.9 Sarcoidosis, unspecified	0.000	0.304	0.696
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.305	0.695
B25 Cytomegaloviral disease	0.000	0.305	0.695
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.000	0.306	0.694
A75-A79 Rickettsioses	0.000	0.306	0.694
A70-A74 Other diseases caused by chlamydiae	0.000	0.306	0.694
A65-A69 Other spirochaetal diseases	0.000	0.306	0.694
A20-A28 Certain zoonotic bacterial diseases	0.000	0.306	0.694
L04 Acute lymphadenitis	0.000	0.307	0.693
L01 Impetigo	0.000	0.307	0.693
L00 Staphylococcal scalded skin syndrome	0.000	0.307	0.693
E50-E64 Other nutritional deficiencies	0.000	0.308	0.692
H73 Other disorders of tympanic membrane	0.000	0.308	0.692
M34 Systemic sclerosis	0.000	0.308	0.692
D68.9 Coagulation defect, unspecified	0.000	0.308	0.692
E74 Other disorders of carbohydrate metabolism	0.000	0.311	0.689
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.000	0.312	0.688
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.313	0.687
B24 Unspecified human immunodeficiency virus [HIV] disease	0.000	0.313	0.687
B48 Other mycoses, not elsewhere classified	0.000	0.313	0.687
B47 Mycetoma	0.000	0.313	0.687
B46 Zygomycosis	0.000	0.313	0.687
B45 Cryptococcosis	0.000	0.313	0.687
B43 Chromomycosis and phaeomycotic abscess	0.000	0.313	0.687
B42 Sporotrichosis	0.000	0.313	0.687
B41 Paracoccidioidomycosis	0.000	0.313	0.687
B40 Blastomycosis	0.000	0.313	0.687
B39 Histoplasmosis	0.000	0.313	0.687
B38 Coccidioidomycosis	0.000	0.313	0.687
B36 Other superficial mycoses	0.000	0.313	0.687
B37.7 Candidal septicaemia	0.000	0.315	0.684
B37.6 Candidal endocarditis	0.000	0.315	0.684
B37.5 Candidal meningitis	0.000	0.315	0.684
H83 Other diseases of inner ear	0.000	0.316	0.684
D69 Purpura and other haemorrhagic conditions	0.000	0.317	0.683
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.317	0.682
E06.9 Thyroiditis, unspecified	0.000	0.318	0.682
F40-F48 Neurotic, stress-related and somatoform disorders	0.000	0.319	0.681
E84 Cystic fibrosis	0.000	0.320	0.680
E79 Disorders of purine and pyrimidine metabolism	0.000	0.320	0.680
E77 Disorders of glycoprotein metabolism	0.000	0.320	0.680
E76 Disorders of glycosaminoglycan metabolism	0.000	0.320	0.680
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.320	0.680
E72 Other disorders of amino-acid metabolism	0.000	0.320	0.680
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.320	0.680
E70 Disorders of aromatic amino-acid metabolism	0.000	0.320	0.680
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.320	0.680
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.000	0.320	0.680
L57.4 Cutis laxa senilis	0.000	0.320	0.680
H80.9 Otosclerosis, unspecified	0.000	0.320	0.680
L10-L14 Bullous disorders	0.000	0.323	0.677
E10.2 With renal complications	0.000	0.323	0.677
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.324	0.676
A15-A19 Tuberculosis	0.000	0.324	0.675
E10.5 With peripheral circulatory complications	0.000	0.326	0.674
F30-F39 Mood [affective] disorders	0.000	0.327	0.673
E87.2 Acidosis	0.000	0.329	0.671
H60-H62 Diseases of external ear	0.000	0.329	0.671
F80-F89 Disorders of psychological development	0.000	0.329	0.671
M46 Other inflammatory spondylopathies	0.000	0.332	0.668
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.332	0.668
D60-D64 Aplastic and other anaemias	0.000	0.332	0.668
E40-E46 Malnutrition	0.000	0.333	0.667
E14 Unspecified diabetes mellitus	0.000	0.334	0.666
M35.7 Hypermobility syndrome	0.000	0.334	0.666
B50-B64 Protozoal diseases	0.000	0.335	0.665
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.337	0.662
H68 Eustachian salpingitis and obstruction	0.000	0.337	0.662
H67 Otitis media in diseases classified elsewhere	0.000	0.337	0.662
M11 Other crystal arthropathies	0.000	0.339	0.661
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.339	0.661
B33 Other viral diseases, not elsewhere classified	0.000	0.339	0.660
B30 Viral conjunctivitis	0.000	0.339	0.660
B27 Infectious mononucleosis	0.000	0.339	0.660
B26 Mumps	0.000	0.339	0.660
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.000	0.340	0.660
H70 Mastoiditis and related conditions	0.000	0.340	0.660
L28 Lichen simplex chronicus and prurigo	0.000	0.341	0.659
E03.8 Other specified hypothyroidism	0.000	0.342	0.658
H65.2 Chronic serous otitis media	0.000	0.343	0.656
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.344	0.656
F60-F69 Disorders of adult personality and behaviour	0.000	0.344	0.656
L24 Irritant contact dermatitis	0.000	0.348	0.652
L21 Seborrhoeic dermatitis	0.000	0.348	0.652
L26 Exfoliative dermatitis	0.000	0.348	0.652
L22 Diaper [napkin] dermatitis	0.000	0.348	0.652
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.348	0.652
H72.1 Attic perforation of tympanic membrane	0.000	0.349	0.651
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.349	0.651
B15-B19 Viral hepatitis	0.000	0.349	0.651
E10.4 With neurological complications	0.000	0.349	0.651
E06.5 Other chronic thyroiditis	0.000	0.351	0.649
E06.4 Drug-induced thyroiditis	0.000	0.351	0.649
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.351	0.649
E06.1 Subacute thyroiditis	0.000	0.351	0.649
E06.0 Acute thyroiditis	0.000	0.351	0.649
M07.6 Other enteropathic arthropathies	0.000	0.352	0.648
M07.5 Arthropathy in ulcerative colitis	0.000	0.352	0.648
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.352	0.648
M07.2 Psoriatic spondylitis	0.000	0.352	0.648
M07.1 Arthritis mutilans	0.000	0.352	0.648
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.352	0.648
M06.4 Inflammatory polyarthropathy	0.000	0.353	0.647
D66 Hereditary factor VIII deficiency	0.000	0.353	0.647
E05.9 Thyrotoxicosis, unspecified	0.000	0.353	0.647
D52 Folate deficiency anaemia	0.000	0.353	0.647
D67 Hereditary factor IX deficiency	0.000	0.353	0.646
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.353	0.646
H65.4 Other chronic nonsuppurative otitis media	0.000	0.354	0.646
D86.0 Sarcoidosis of lung	0.000	0.354	0.646
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.356	0.644
L20 Atopic dermatitis	0.000	0.356	0.644
E12 Malnutrition-related diabetes mellitus	0.000	0.361	0.639
M99 Biomechanical lesions, not elsewhere classified	0.000	0.361	0.639
B37.9 Candidiasis, unspecified	0.000	0.361	0.639
B35.1 Tinea unguium	0.000	0.361	0.639
B90-B94 Sequelae of infectious and parasitic diseases	0.000	0.362	0.638
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.363	0.636
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.365	0.635
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.365	0.635
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.365	0.635
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.365	0.635
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.365	0.635
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.365	0.635
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.365	0.635
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.365	0.635
M06.3 Rheumatoid nodule	0.000	0.366	0.634
L25 Unspecified contact dermatitis	0.000	0.366	0.634
B34.3 Parvovirus infection, unspecified	0.000	0.367	0.633
B34.2 Coronavirus infection, unspecified	0.000	0.367	0.633
B34.1 Enterovirus infection, unspecified	0.000	0.367	0.633
B34.0 Adenovirus infection, unspecified	0.000	0.367	0.633
E85 Amyloidosis	0.000	0.367	0.632
D51 Vitamin B12 deficiency anaemia	0.000	0.368	0.632
M60-M63 Disorders of muscles	0.000	0.369	0.630
B65-B83 Helminthiases	0.000	0.370	0.630
D68.0 Von Willebrand's disease	0.000	0.370	0.630
B85-B89 Pediculosis, acariasis and other infestations	0.000	0.372	0.628
B37.4 Candidiasis of other urogenital sites	0.000	0.373	0.627
M49 Spondylopathies in diseases classified elsewhere	0.000	0.373	0.627
B37.1 Pulmonary candidiasis	0.000	0.373	0.627
M91-M94 Chondropathies	0.000	0.375	0.625
B37.2 Candidiasis of skin and nail	0.000	0.376	0.624
E10.7 With multiple complications	0.000	0.377	0.623
E10.0 With coma	0.000	0.377	0.623
E07 Other disorders of thyroid	0.000	0.377	0.622
E05.5 Thyroid crisis or storm	0.000	0.381	0.619
E05.4 Thyrotoxicosis factitia	0.000	0.381	0.619
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.381	0.619
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.381	0.619
E22 Hyperfunction of pituitary gland	0.000	0.382	0.618
D59 Acquired haemolytic anaemia	0.000	0.382	0.618
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.382	0.617
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.382	0.617
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.382	0.617
E89.5 Postprocedural testicular hypofunction	0.000	0.382	0.617
E89.4 Postprocedural ovarian failure	0.000	0.382	0.617
E89.1 Postprocedural hypoinsulinaemia	0.000	0.382	0.617
L23 Allergic contact dermatitis	0.000	0.383	0.617
B99 Other and unspecified infectious diseases	0.000	0.384	0.616
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.385	0.615
L05.0 Pilonidal cyst with abscess	0.000	0.385	0.615
B34.4 Papovirus infection, unspecified	0.000	0.388	0.612
M05.8 Other seropositive rheumatoid arthritis	0.000	0.390	0.610
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.390	0.610
M05.2 Rheumatoid vasculitis	0.000	0.390	0.610
M05.1 Rheumatoid lung disease	0.000	0.390	0.610
M05.0 Felty's syndrome	0.000	0.390	0.610
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.000	0.390	0.609
M95.8 Other specified acquired deformities of musculoskeletal system	0.000	0.390	0.609
M95.5 Acquired deformity of pelvis	0.000	0.390	0.609
M95.4 Acquired deformity of chest and rib	0.000	0.390	0.609
M95.3 Acquired deformity of neck	0.000	0.390	0.609
M95.2 Other acquired deformity of head	0.000	0.390	0.609
M95.1 Cauliflower ear	0.000	0.390	0.609
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.391	0.609
F31 Bipolar affective disorder	0.000	0.391	0.609
E89.3 Postprocedural hypopituitarism	0.000	0.395	0.605
M07.38 Other psoriatic arthropathies (Other)	0.000	0.395	0.605
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.395	0.605
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.395	0.605
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.395	0.605
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.395	0.605
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.395	0.605
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.395	0.605
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.395	0.605
F42 Obsessive-compulsive disorder	0.000	0.395	0.605
H65.3 Chronic mucoid otitis media	0.000	0.396	0.604
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.396	0.604
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.397	0.603
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.000	0.398	0.602
D50.8 Other iron deficiency anaemias	0.000	0.398	0.602
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.398	0.601
H65.1 Other acute nonsuppurative otitis media	0.000	0.400	0.599
H65.0 Acute serous otitis media	0.000	0.400	0.599
D68.2 Hereditary deficiency of other clotting factors	0.000	0.400	0.599
E73.9 Lactose intolerance, unspecified	0.000	0.401	0.598
E87.7 Fluid overload	0.000	0.401	0.599
D53 Other nutritional anaemias	0.000	0.402	0.598
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.406	0.594
L29.9 Pruritus, unspecified	0.000	0.406	0.594
D84 Other immunodeficiencies	0.000	0.407	0.593
D83 Common variable immunodeficiency	0.000	0.407	0.593
D82 Immunodeficiency associated with other major defects	0.000	0.407	0.593
D81 Combined immunodeficiencies	0.000	0.407	0.593
H69 Other disorders of Eustachian tube	0.000	0.407	0.593
D68.4 Acquired coagulation factor deficiency	0.000	0.410	0.590
D68.1 Hereditary factor XI deficiency	0.000	0.410	0.590
L42 Pityriasis rosea	0.000	0.411	0.588
M30 Polyarteritis nodosa and related conditions	0.000	0.412	0.588
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.412	0.588
L30.8 Other specified dermatitis	0.000	0.412	0.588
D64 Other anaemias	0.000	0.413	0.587
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.414	0.586
E89.2 Postprocedural hypoparathyroidism	0.000	0.415	0.585
M34.9 Systemic sclerosis, unspecified	0.000	0.415	0.585
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.416	0.584
M35.8 Other specified systemic involvement of connective tissue	0.000	0.416	0.584
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.416	0.584
M35.5 Multifocal fibrosclerosis	0.000	0.416	0.584
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.416	0.584
M35.2 Behcet's disease	0.000	0.416	0.584
M35.1 Other overlap syndromes	0.000	0.416	0.584
F70-F79 Mental retardation	0.000	0.416	0.583
E10.8 With unspecified complications	0.000	0.417	0.583
L29.8 Other pruritus	0.000	0.418	0.582
L29.3 Anogenital pruritus, unspecified	0.000	0.418	0.582
L29.1 Pruritus scroti	0.000	0.418	0.582
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.000	0.418	0.582
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.419	0.581
M32 Systemic lupus erythematosus	0.000	0.419	0.581
M00 Pyogenic arthritis	0.000	0.419	0.581
L08.1 Erythrasma	0.000	0.421	0.579
L08.0 Pyoderma	0.000	0.421	0.579
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.000	0.423	0.576
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions	0.000	0.423	0.576
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases	0.000	0.423	0.576
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms	0.000	0.423	0.576
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases	0.000	0.423	0.576
M22 Disorders of patella	0.000	0.426	0.574
H83.0 Labyrinthitis	0.000	0.428	0.572
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.428	0.572
E83 Disorders of mineral metabolism	0.000	0.429	0.571
F43 Reaction to severe stress, and adjustment disorders	0.000	0.430	0.570
E87.4 Mixed disorder of acid-base balance	0.000	0.430	0.570
B35.3 Tinea pedis	0.000	0.430	0.570
F81 Specific developmental disorders of scholastic skills	0.000	0.431	0.569
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.431	0.569
L40.0 Psoriasis vulgaris	0.000	0.433	0.567
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.433	0.567
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.433	0.567
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.433	0.567
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.433	0.567
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.433	0.567
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.433	0.567
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.433	0.567
H72.2 Other marginal perforations of tympanic membrane	0.000	0.434	0.565
R21 Rash and other nonspecific skin eruption	0.000	0.436	0.564
L43 Lichen planus	0.000	0.436	0.564
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.437	0.563
E14.9 Without complications	0.000	0.437	0.563
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.000	0.438	0.562
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.439	0.561
E32 Diseases of thymus	0.000	0.439	0.561
E31 Polyglandular dysfunction	0.000	0.439	0.561
E30 Disorders of puberty, not elsewhere classified	0.000	0.439	0.561
E25 Adrenogenital disorders	0.000	0.439	0.561
E20 Hypoparathyroidism	0.000	0.439	0.561
E10.6 With other specified complications	0.000	0.441	0.559
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.000	0.441	0.559
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.442	0.558
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.442	0.558
D69.5 Secondary thrombocytopenia	0.000	0.443	0.557
B37.3 Candidiasis of vulva and vagina	0.000	0.443	0.557
B35.9 Dermatophytosis, unspecified	0.000	0.443	0.557
B35.8 Other dermatophytoses	0.000	0.443	0.557
B35.6 Tinea cruris	0.000	0.443	0.557
B35.5 Tinea imbricata	0.000	0.443	0.557
B35.4 Tinea corporis	0.000	0.443	0.557
B35.2 Tinea manuum	0.000	0.443	0.557
B35.0 Tinea barbae and tinea capitis	0.000	0.443	0.557
D68.6 Other Thrombophilia	0.000	0.444	0.556
Chapter IX Diseases of the circulatory system	0.000	0.444	0.556
L50-L54 Urticaria and erythema	0.000	0.445	0.555
H72.8 Other perforations of tympanic membrane	0.000	0.445	0.554
M10 Gout	0.000	0.446	0.554
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.447	0.553
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.450	0.550
A80-A89 Viral infections of the central nervous system	0.000	0.450	0.550
F20 Schizophrenia	0.000	0.450	0.550
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.450	0.550
H66 Suppurative and unspecified otitis media	0.000	0.451	0.549
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.452	0.548
D86.3 Sarcoidosis of skin	0.000	0.454	0.546
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.454	0.546
D86.1 Sarcoidosis of lymph nodes	0.000	0.454	0.546
D57 Sickle-cell disorders	0.000	0.455	0.545
D56 Thalassaemia	0.000	0.455	0.545
D55 Anaemia due to enzyme disorders	0.000	0.455	0.545
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.455	0.545
F99-F99 Unspecified mental disorder	0.000	0.455	0.545
M13 Other arthritis	0.000	0.455	0.545
B95-B98 Bacterial, viral and other infectious agents	0.000	0.457	0.543
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.457	0.543
B49 Unspecified mycosis	0.000	0.458	0.541
M80-M85 Disorders of bone density and structure	0.001	0.458	0.540
E26 Hyperaldosteronism	0.000	0.459	0.541
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.459	0.541
M33 Dermatopolymyositis	0.000	0.459	0.541
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.460	0.540
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.460	0.540
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.460	0.540
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.460	0.540
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.460	0.540
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.460	0.540
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.460	0.540
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.000	0.463	0.537
M02 Reactive arthropathies	0.000	0.463	0.537
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.000	0.463	0.537
M34.1 CR(E)ST syndrome	0.000	0.464	0.536
E27.5 Adrenomedullary hyperfunction	0.000	0.464	0.536
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.464	0.536
E27.2 Addisonian crisis	0.000	0.464	0.536
E27.0 Other adrenocortical overactivity	0.000	0.464	0.536
H80.8 Other otosclerosis	0.000	0.464	0.536
H80.2 Cochlear otosclerosis	0.000	0.464	0.536
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.464	0.536
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.464	0.536
F40 Phobic anxiety disorders	0.000	0.464	0.536
E13 Other specified diabetes mellitus	0.000	0.466	0.534
E73.8 Other lactose intolerance	0.000	0.466	0.534
E73.1 Secondary lactase deficiency	0.000	0.466	0.534
E73.0 Congenital lactase deficiency	0.000	0.466	0.534
R26 Abnormalities of gait and mobility	0.000	0.466	0.534
F30 Manic episode	0.000	0.466	0.534
B25.9 Cytomegaloviral disease, unspecified	0.000	0.467	0.533
A59 Trichomoniasis	0.000	0.467	0.532
A56 Other sexually transmitted chlamydial diseases	0.000	0.467	0.532
A54 Gonococcal infection	0.000	0.467	0.532
A53 Other and unspecified syphilis	0.000	0.467	0.532
A52 Late syphilis	0.000	0.467	0.532
A51 Early syphilis	0.000	0.467	0.532
A50 Congenital syphilis	0.000	0.467	0.532
A64 Unspecified sexually transmitted disease	0.000	0.467	0.532
A58 Granuloma inguinale	0.000	0.467	0.532
A57 Chancroid	0.000	0.467	0.532

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations