TreeWAS – Variant ID: rs2523898

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
L40 Psoriasis	0.000	0.000	1.000
E10.3 With ophthalmic complications	0.000	0.001	0.999
L40.5 Arthropathic psoriasis	0.000	0.002	0.998
K51.9 Ulcerative colitis, unspecified	0.998	0.002	0.000
K51 Ulcerative colitis	0.997	0.003	0.000
E10-E14 Diabetes mellitus	0.000	0.012	0.988
K51.4 Pseudopolyposis of colon	0.987	0.013	0.000
E10.1 With ketoacidosis	0.000	0.024	0.976
L40.0 Psoriasis vulgaris	0.000	0.039	0.961
E11 Non-insulin-dependent diabetes mellitus	0.000	0.060	0.940
K51.8 Other ulcerative colitis	0.932	0.068	0.000
E14 Unspecified diabetes mellitus	0.000	0.073	0.927
K51.3 Ulcerative (chronic) rectosigmoiditis	0.922	0.078	0.000
K51.5 Mucosal proctocolitis	0.916	0.084	0.000
E14.3 With ophthalmic complications	0.000	0.122	0.878
L40.1 Generalised pustular psoriasis	0.000	0.140	0.860
E11.1 With ketoacidosis	0.000	0.151	0.849
E10.4 With neurological complications	0.000	0.155	0.845
E13 Other specified diabetes mellitus	0.000	0.157	0.843
J45.9 Asthma, unspecified	0.000	0.178	0.822
E10.2 With renal complications	0.000	0.179	0.821
L40.4 Guttate psoriasis	0.000	0.189	0.811
E10.0 With coma	0.000	0.191	0.809
E10.8 With unspecified complications	0.000	0.194	0.806
E11.9 Without complications	0.000	0.206	0.794
K51.1 Ulcerative (chronic) ileocolitis	0.790	0.210	0.000
E14.2 Withrenal complications	0.000	0.214	0.786
E11.6 With other specified complications	0.000	0.217	0.783
K90 Intestinal malabsorption	0.000	0.219	0.781
E14.1 With ketoacidosis	0.000	0.227	0.773
E10.6 With other specified complications	0.000	0.229	0.770
E13.9 Without complications	0.000	0.241	0.759
E11.4 With neurological complications	0.000	0.244	0.756
K51.2 Ulcerative (chronic) proctitis	0.722	0.278	0.000
E10.7 With multiple complications	0.000	0.283	0.717
L40.2 Acrodermatitis continua	0.000	0.283	0.717
E11.2 With renal complications	0.000	0.290	0.710
E12 Malnutrition-related diabetes mellitus	0.000	0.291	0.709
E11.3 With ophthalmic complications	0.000	0.292	0.708
L40.3 Pustulosis palmaris et plantaris	0.000	0.303	0.697
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.308	0.692
E14.8 With unspecified complications	0.000	0.323	0.677
L40.8 Other psoriasis	0.000	0.323	0.677
E11.7 With multiple complications	0.000	0.326	0.674
E14.7 With multiple complications	0.000	0.335	0.665
E14.0 With coma	0.000	0.335	0.665
E11.8 With unspecified complications	0.000	0.338	0.662
E14.4 With neurological complications	0.000	0.339	0.661
E14.6 With other specified complications	0.000	0.341	0.659
K90.8 Other intestinal malabsorption	0.000	0.381	0.619
E10.5 With peripheral circulatory complications	0.000	0.383	0.617
E11.0 With coma	0.000	0.383	0.617
K90.9 Intestinal malabsorption, unspecified	0.000	0.385	0.615
E13.8 With unspecified complications	0.000	0.396	0.604
E13.7 With multiple complications	0.000	0.396	0.604
E13.6 With other specified complications	0.000	0.396	0.604
E13.5 With peripheral circulatory complications	0.000	0.396	0.604
E13.4 With neurological complications	0.000	0.396	0.604
E13.2 With renal complications	0.000	0.396	0.604
E13.1 With ketoacidosis	0.000	0.396	0.604
E13.0 With coma	0.000	0.396	0.604
E16.2 Hypoglycaemia, unspecified	0.000	0.407	0.593
E16 Other disorders of pancreatic internal secretion	0.000	0.414	0.586
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.428	0.572
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.437	0.563
K90.3 Pancreatic steatorrhoea	0.000	0.440	0.560
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.440	0.560
K90.1 Tropical sprue	0.000	0.440	0.560
E14.5 With peripheral circulatory complications	0.000	0.448	0.552
K51.0 Ulcerative (chronic) enterocolitis	0.548	0.451	0.000
E13.3 With ophthalmic complications	0.000	0.453	0.547
E12.9 Without complications	0.000	0.492	0.508
E12.8 With unspecified complications	0.000	0.492	0.508
E12.7 With multiple complications	0.000	0.492	0.508
E12.6 With other specified complications	0.000	0.492	0.508
E12.5 With peripheral circulatory complications	0.000	0.492	0.508
E12.4 With neurological complications	0.000	0.492	0.508
E12.3 With ophthalmic complications	0.000	0.492	0.508
E12.2 With renal complications	0.000	0.492	0.508
E12.1 With ketoacidosis	0.000	0.492	0.508
E12.0 With coma	0.000	0.492	0.508
E16.1 Other hypoglycaemia	0.000	0.506	0.494
E11.5 With peripheral circulatory complications	0.000	0.536	0.464
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.542	0.458
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.580	0.420
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.580	0.420
E16.4 Abnormal secretion of gastrin	0.000	0.580	0.420
E16.3 Increased secretion of glucagon	0.000	0.580	0.420
E14.9 Without complications	0.000	0.584	0.416
E40-E46 Malnutrition	0.000	0.587	0.413
E15 Nondiabetic hypoglycaemic coma	0.000	0.589	0.410
E46 Unspecified protein-energy malnutrition	0.000	0.695	0.305
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.704	0.296
E45 Retarded development following protein-energy malnutrition	0.000	0.704	0.296
E43 Unspecified severe protein-energy malnutrition	0.000	0.704	0.296
E42 Marasmic kwashiorkor	0.000	0.704	0.296
E41 Nutritional marasmus	0.000	0.704	0.296
E40 Kwashiorkor	0.000	0.704	0.296
J45 Asthma	0.000	0.706	0.294
L40-L45 Papulosquamous disorders	0.000	0.723	0.277
E50-E64 Other nutritional deficiencies	0.000	0.732	0.268
E00-E07 Disorders of thyroid gland	0.000	0.757	0.243
J45.1 Nonallergic asthma	0.000	0.763	0.237
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.774	0.226
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.781	0.219
E44.1 Mild protein-energy malnutrition	0.000	0.788	0.212
E44.0 Moderate protein-energy malnutrition	0.000	0.788	0.212
J45.8 Mixed asthma	0.000	0.793	0.207
L42 Pityriasis rosea	0.000	0.795	0.205
E65-E68 Obesity and other hyperalimentation	0.000	0.797	0.203
L44 Other papulosquamous disorders	0.000	0.801	0.199
L41 Parapsoriasis	0.000	0.801	0.199
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.801	0.199
E51 Thiamine deficiency	0.000	0.802	0.198
E56 Other vitamin deficiencies	0.000	0.805	0.195
E58 Dietary calcium deficiency	0.000	0.806	0.194
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.808	0.192
E63 Other nutritional deficiencies	0.000	0.808	0.192
E50 Vitamin A deficiency	0.000	0.808	0.192
E60 Dietary zinc deficiency	0.000	0.808	0.192
E59 Dietary selenium deficiency	0.000	0.808	0.192
E52 Niacin deficiency [pellagra]	0.000	0.808	0.192
K50-K52 Noninfective enteritis and colitis	0.192	0.808	0.001
E55 Vitamin D deficiency	0.000	0.812	0.188
E05.9 Thyrotoxicosis, unspecified	0.000	0.813	0.187
E54 Ascorbic acid deficiency	0.000	0.824	0.176
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.825	0.175
E00 Congenital iodine-deficiency syndrome	0.000	0.825	0.175
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.835	0.165
E05.5 Thyroid crisis or storm	0.000	0.838	0.162
E05.4 Thyrotoxicosis factitia	0.000	0.838	0.162
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.838	0.162
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.838	0.162
E20-E35 Disorders of other endocrine glands	0.000	0.847	0.153
E53 Deficiency of other B group vitamins	0.000	0.848	0.152
E07 Other disorders of thyroid	0.000	0.849	0.151
E03 Other hypothyroidism	0.000	0.850	0.150
E51.2 Wernicke's encephalopathy	0.000	0.852	0.148
E67 Other hyperalimentation	0.000	0.854	0.145
E68 Sequelae of hyperalimentation	0.000	0.854	0.145
E56.1 Deficiency of vitamin K	0.000	0.857	0.143
L41.9 Parapsoriasis, unspecified	0.000	0.857	0.143
L41.8 Other parapsoriasis	0.000	0.857	0.143
L41.5 Retiform parapsoriasis	0.000	0.857	0.143
L41.4 Large plaque parapsoriasis	0.000	0.857	0.143
L41.3 Small plaque parapsoriasis	0.000	0.857	0.143
L41.2 Lymphomatoid papulosis	0.000	0.857	0.143
L41.1 Pityriasis lichenoides chronica	0.000	0.857	0.143
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.857	0.143
L44.9 Papulosquamous disorder, unspecified	0.000	0.857	0.143
L44.8 Other specified papulosquamous disorders	0.000	0.857	0.143
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.857	0.143
L44.3 Lichen ruber moniliformis	0.000	0.857	0.143
L44.2 Lichen striatus	0.000	0.857	0.143
L44.1 Lichen nitidus	0.000	0.857	0.143
L44.0 Pityriasis rubra pilaris	0.000	0.857	0.143
E51.9 Thiamine deficiency, unspecified	0.000	0.858	0.142
E51.8 Other manifestations of thiamine deficiency	0.000	0.858	0.142
E51.1 Beriberi	0.000	0.858	0.142
E61 Deficiency of other nutrient elements	0.000	0.858	0.142
E56.9 Vitamin deficiency, unspecified	0.000	0.860	0.140
E56.8 Deficiency of other vitamins	0.000	0.860	0.140
E56.0 Deficiency of vitamin E	0.000	0.860	0.140
E05.8 Other thyrotoxicosis	0.000	0.860	0.140
E50.9 Vitamin A deficiency, unspecified	0.000	0.862	0.138
E50.8 Other manifestations of vitamin A deficiency	0.000	0.862	0.138
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.862	0.138
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.862	0.138
E50.5 Vitamin A deficiency with night blindness	0.000	0.862	0.138
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.862	0.138
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.862	0.138
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.862	0.138
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.862	0.138
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.862	0.138
E63.9 Nutritional deficiency, unspecified	0.000	0.862	0.138
E63.8 Other specified nutritional deficiencies	0.000	0.862	0.138
E63.1 Imbalance of constituents of food intake	0.000	0.862	0.138
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.862	0.138
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.862	0.138
E64.8 Sequelae of other nutritional deficiencies	0.000	0.862	0.138
E64.3 Sequelae of rickets	0.000	0.862	0.138
E64.2 Sequelae of vitamin C deficiency	0.000	0.862	0.138
E64.1 Sequelae of vitamin A deficiency	0.000	0.862	0.138
E64.0 Sequelae of protein-energy malnutrition	0.000	0.862	0.138
E24 Cushing's syndrome	0.000	0.864	0.136
E55.0 Rickets, active	0.000	0.865	0.135
E55.9 Vitamin D deficiency, unspecified	0.000	0.869	0.131
E03.8 Other specified hypothyroidism	0.000	0.869	0.131
E24.0 Pituitary-dependent Cushing's disease	0.000	0.873	0.127
E07.8 Other specified disorders of thyroid	0.000	0.874	0.126
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.874	0.125
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.874	0.125
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.874	0.125
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.874	0.125
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.874	0.125
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.874	0.125
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.874	0.125
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.874	0.125
E27 Other disorders of adrenal gland	0.000	0.879	0.121
J45.0 Predominantly allergic asthma	0.000	0.882	0.118
E06 Thyroiditis	0.000	0.882	0.118
L43 Lichen planus	0.000	0.883	0.117
E25 Adrenogenital disorders	0.000	0.886	0.114
E53.9 Vitamin B deficiency, unspecified	0.000	0.888	0.111
E27.1 Primary adrenocortical insufficiency	0.000	0.889	0.111
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.890	0.110
E32 Diseases of thymus	0.000	0.890	0.110
E30 Disorders of puberty, not elsewhere classified	0.000	0.890	0.110
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.891	0.109
E53.1 Pyridoxine deficiency	0.000	0.891	0.109
E53.0 Riboflavin deficiency	0.000	0.891	0.109
K72 Hepatic failure, not elsewhere classified	0.000	0.891	0.109
E07.1 Dyshormogenetic goitre	0.000	0.892	0.108
E07.0 Hypersecretion of calcitonin	0.000	0.892	0.108
E65 Localised adiposity	0.000	0.892	0.108
E03.5 Myxoedema coma	0.000	0.892	0.107
E03.4 Atrophy of thyroid (acquired)	0.000	0.892	0.107
E03.3 Postinfectious hypothyroidism	0.000	0.892	0.107
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.892	0.107
E31 Polyglandular dysfunction	0.000	0.893	0.106
E03.1 Congenital hypothyroidism without goitre	0.000	0.894	0.106
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.894	0.106
K72.0 Acute and subacute hepatic failure	0.000	0.894	0.106
K72.9 Hepatic failure, unspecified	0.000	0.895	0.105
E67.8 Other specified hyperalimentation	0.000	0.895	0.104
E67.3 Hypervitaminosis D	0.000	0.895	0.104
E67.2 Megavitamin-B6 syndrome	0.000	0.895	0.104
E67.1 Hypercarotenaemia	0.000	0.895	0.104
E67.0 Hypervitaminosis A	0.000	0.895	0.104
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.897	0.103
E61.9 Deficiency of nutrient element, unspecified	0.000	0.898	0.102
E61.8 Deficiency of other specified nutrient elements	0.000	0.898	0.102
E61.7 Deficiency of multiple nutrient elements	0.000	0.898	0.102
E61.6 Vanadium deficiency	0.000	0.898	0.102
E61.5 Molybdenum deficiency	0.000	0.898	0.102
E61.4 Chromium deficiency	0.000	0.898	0.102
E61.3 Manganese deficiency	0.000	0.898	0.102
E61.0 Copper deficiency	0.000	0.898	0.102
K70-K77 Diseases of liver	0.000	0.899	0.101
K50 Crohn's disease [regional enteritis]	0.101	0.899	0.000
E34 Other endocrine disorders	0.000	0.899	0.100
E20 Hypoparathyroidism	0.000	0.900	0.100
K73 Chronic hepatitis, not elsewhere classified	0.000	0.901	0.099
E24.2 Drug-induced Cushing's syndrome	0.000	0.901	0.099
K73.9 Chronic hepatitis, unspecified	0.000	0.901	0.099
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.902	0.097
E24.3 Ectopic ACTH syndrome	0.000	0.902	0.097
E24.1 Nelson's syndrome	0.000	0.902	0.097
E29 Testicular dysfunction	0.000	0.903	0.097
E23 Hypofunction and other disorders of pituitary gland	0.000	0.904	0.096
K75.4 Autoimmune hepatitis	0.000	0.905	0.095
K52 Other non-infective gastro-enteritis and colitis	0.094	0.906	0.000
K75 Other inflammatory liver diseases	0.000	0.906	0.094
E61.2 Magnesium deficiency	0.000	0.909	0.090
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.910	0.090
E24.9 Cushing's syndrome, unspecified	0.000	0.910	0.090
E24.8 Other Cushing's syndrome	0.000	0.910	0.089
E22 Hyperfunction of pituitary gland	0.000	0.913	0.087
E27.5 Adrenomedullary hyperfunction	0.000	0.913	0.087
E27.0 Other adrenocortical overactivity	0.000	0.913	0.087
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.914	0.086
K52.1 Toxic gastro-enteritis and colitis	0.086	0.914	0.000
E06.9 Thyroiditis, unspecified	0.000	0.915	0.085
K72.1 Chronic hepatic failure	0.000	0.915	0.085
K50.8 Other Crohn's disease	0.085	0.915	0.000
E06.4 Drug-induced thyroiditis	0.000	0.915	0.084
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.915	0.084
E06.0 Acute thyroiditis	0.000	0.915	0.084
L43.3 Subacute (active) lichen planus	0.000	0.916	0.084
L43.2 Lichenoid drug reaction	0.000	0.916	0.084
L43.1 Bullous lichen planus	0.000	0.916	0.084
L43.0 Hypertrophic lichen planus	0.000	0.916	0.084
E23.7 Disorder of pituitary gland, unspecified	0.000	0.916	0.084
E34.9 Endocrine disorder, unspecified	0.000	0.917	0.083
E25.9 Adrenogenital disorder, unspecified	0.000	0.918	0.082
E25.8 Other adrenogenital disorders	0.000	0.918	0.082
K74 Fibrosis and cirrhosis of liver	0.000	0.918	0.082
E27.9 Disorder of adrenal gland, unspecified	0.000	0.919	0.081
E30.9 Disorder of puberty, unspecified	0.000	0.921	0.079
E30.8 Other disorders of puberty	0.000	0.921	0.079
E30.1 Precocious puberty	0.000	0.921	0.079
E30.0 Delayed puberty	0.000	0.921	0.079
E32.9 Disease of thymus, unspecified	0.000	0.921	0.079
E32.8 Other diseases of thymus	0.000	0.921	0.079
E32.1 Abscess of thymus	0.000	0.921	0.079
E32.0 Persistent hyperplasia of thymus	0.000	0.921	0.079
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.921	0.079
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.921	0.079
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.921	0.079
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.079	0.921	0.000
K50.9 Crohn's disease, unspecified	0.079	0.921	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.923	0.077
K76 Other diseases of liver	0.000	0.923	0.077
E31.9 Polyglandular dysfunction, unspecified	0.000	0.923	0.076
E31.8 Other polyglandular dysfunction	0.000	0.923	0.076
E31.1 Polyglandular hyperfunction	0.000	0.923	0.076
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.924	0.076
E06.5 Other chronic thyroiditis	0.000	0.924	0.076
E26 Hyperaldosteronism	0.000	0.924	0.076
K75.8 Other specified inflammatory liver diseases	0.000	0.926	0.074
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.926	0.073
E06.1 Subacute thyroiditis	0.000	0.927	0.073
E23.6 Other disorders of pituitary gland	0.000	0.927	0.073
E31.0 Autoimmune polyglandular failure	0.000	0.927	0.073
K71 Toxic liver disease	0.000	0.927	0.073
K77 Liver disorders in diseases classified elsewhere	0.000	0.927	0.073
E34.5 Androgen resistance syndrome	0.000	0.928	0.072
E34.4 Constitutional tall stature	0.000	0.928	0.072
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.928	0.072
E34.1 Other hypersecretion of intestinal hormones	0.000	0.928	0.072
E61.1 Iron deficiency	0.000	0.928	0.072
E34.3 Short stature, not elsewhere classified	0.000	0.928	0.072
E20.8 Other hypoparathyroidism	0.000	0.928	0.072
E20.1 Pseudohypoparathyroidism	0.000	0.928	0.072
E20.0 Idiopathic hypoparathyroidism	0.000	0.928	0.072
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.929	0.071
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.929	0.071
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.929	0.071
E29.9 Testicular dysfunction, unspecified	0.000	0.930	0.070
E29.8 Other testicular dysfunction	0.000	0.930	0.070
E29.0 Testicular hyperfunction	0.000	0.930	0.070
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.931	0.069
E23.1 Drug-induced hypopituitarism	0.000	0.931	0.069
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.931	0.069
K75.2 Nonspecific reactive hepatitis	0.000	0.933	0.067
K75.1 Phlebitis of portal vein	0.000	0.933	0.067
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.933	0.067
L43.8 Other lichen planus	0.000	0.933	0.067
E21.2 Other hyperparathyroidism	0.000	0.934	0.066
E22.1 Hyperprolactinaemia	0.000	0.934	0.066
E21.4 Other specified disorders of parathyroid gland	0.000	0.935	0.064
E53.8 Deficiency of other specified B group vitamins	0.000	0.935	0.065
E27.2 Addisonian crisis	0.000	0.936	0.064
E21.0 Primary hyperparathyroidism	0.000	0.936	0.064
K52.3 Indeterminate colitis	0.064	0.936	0.000
E34.8 Other specified endocrine disorders	0.000	0.936	0.064
K52.0 Gastro-enteritis and colitis due to radiation	0.063	0.936	0.000
K76.6 Portal hypertension	0.000	0.937	0.063
K76.9 Liver disease, unspecified	0.000	0.937	0.063
E06.3 Autoimmune thyroiditis	0.000	0.937	0.063
K90-K93 Other diseases of the digestive system	0.000	0.937	0.063
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.937	0.062
E22.8 Other hyperfunction of pituitary gland	0.000	0.937	0.062
K76.8 Other specified diseases of liver	0.000	0.938	0.062
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.938	0.061
E20.9 Hypoparathyroidism, unspecified	0.000	0.939	0.061
K76.7 Hepatorenal syndrome	0.000	0.941	0.059
K74.4 Secondary biliary cirrhosis	0.000	0.941	0.059
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.941	0.059
E28 Ovarian dysfunction	0.000	0.942	0.058
E23.2 Diabetes insipidus	0.000	0.942	0.057
E29.1 Testicular hypofunction	0.000	0.943	0.057
E27.8 Other specified disorders of adrenal gland	0.000	0.944	0.056
K74.1 Hepatic sclerosis	0.000	0.944	0.056
E22.0 Acromegaly and pituitary gigantism	0.000	0.944	0.056
K76.3 Infarction of liver	0.000	0.944	0.056
K76.5 Hepatic veno-occlusive disease	0.000	0.945	0.055
K76.4 Peliosis hepatis	0.000	0.945	0.055
K76.2 Central haemorrhagic necrosis of liver	0.000	0.945	0.055
E34.0 Carcinoid syndrome	0.000	0.945	0.055
E26.8 Other hyperaldosteronism	0.000	0.945	0.054
E26.1 Secondary hyperaldosteronism	0.000	0.945	0.054
K74.5 Biliary cirrhosis, unspecified	0.000	0.946	0.054
K71.0 Toxic liver disease with cholestasis	0.000	0.947	0.053
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.947	0.053
K74.0 Hepatic fibrosis	0.000	0.948	0.052
K71.8 Toxic liver disease with other disorders of liver	0.000	0.948	0.052
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.948	0.052
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.948	0.052
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.948	0.052
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.948	0.052
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.948	0.052
K71.2 Toxic liver disease with acute hepatitis	0.000	0.948	0.052
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.948	0.052
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.948	0.052
J46 Status asthmaticus	0.000	0.948	0.052
K50.1 Crohn's disease of large intestine	0.052	0.948	0.000
K76.1 Chronic passive congestion of liver	0.000	0.949	0.051
K71.9 Toxic liver disease, unspecified	0.000	0.949	0.050
K75.9 Inflammatory liver disease, unspecified	0.000	0.950	0.050
K31.8 Other specified diseases of stomach and duodenum	0.000	0.950	0.050
E70-E90 Metabolic disorders	0.000	0.952	0.048
E78.2 Mixed hyperlipidaemia	0.000	0.953	0.047
E66 Obesity	0.000	0.953	0.047
J40-J47 Chronic lower respiratory diseases	0.000	0.954	0.046
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.954	0.046
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.954	0.045
E26.9 Hyperaldosteronism, unspecified	0.000	0.955	0.044
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.956	0.044
K74.3 Primary biliary cirrhosis	0.000	0.957	0.043
E78.8 Other disorders of lipoprotein metabolism	0.000	0.957	0.043
E28.9 Ovarian dysfunction, unspecified	0.000	0.958	0.042
E28.8 Other ovarian dysfunction	0.000	0.958	0.042
E28.1 Androgen excess	0.000	0.958	0.042
E28.0 Oestrogen excess	0.000	0.958	0.042
L43.9 Lichen planus, unspecified	0.000	0.958	0.042
E88 Other metabolic disorders	0.000	0.960	0.040
E78.1 Pure hyperglyceridaemia	0.000	0.962	0.038
E26.0 Primary hyperaldosteronism	0.000	0.962	0.038
E74 Other disorders of carbohydrate metabolism	0.000	0.962	0.038
E79 Disorders of purine and pyrimidine metabolism	0.000	0.962	0.037
E07.9 Disorder of thyroid, unspecified	0.000	0.964	0.036
E72 Other disorders of amino-acid metabolism	0.000	0.964	0.036
E66.0 Obesity due to excess calories	0.000	0.965	0.035
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.965	0.035
E77 Disorders of glycoprotein metabolism	0.000	0.965	0.035
E76 Disorders of glycosaminoglycan metabolism	0.000	0.965	0.035
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.965	0.035
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.965	0.035
E78.4 Other hyperlipidaemia	0.000	0.966	0.034
E85 Amyloidosis	0.000	0.966	0.034
E66.1 Drug-induced obesity	0.000	0.966	0.033
E70 Disorders of aromatic amino-acid metabolism	0.000	0.967	0.033
E88.8 Other specified metabolic disorders	0.000	0.967	0.033
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.967	0.033
K93.1 Megacolon in Chagas' disease	0.000	0.967	0.033
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.967	0.033
E88.9 Metabolic disorder, unspecified	0.000	0.967	0.033
J41 Simple and mucopurulent chronic bronchitis	0.000	0.967	0.032
K75.0 Abscess of liver	0.000	0.968	0.032
E88.2 Lipomatosis, not elsewhere classified	0.000	0.968	0.032
E78.6 Lipoprotein deficiency	0.000	0.968	0.032
E84 Cystic fibrosis	0.000	0.968	0.032
E78.3 Hyperchylomicronaemia	0.000	0.969	0.030
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.970	0.030
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.970	0.030
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.970	0.030
E88.3 Tumour lysis syndrome	0.000	0.972	0.028
E28.3 Primary ovarian failure	0.000	0.972	0.028
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.973	0.027
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.973	0.027
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.973	0.027
E74.2 Disorders of galactose metabolism	0.000	0.973	0.027
E74.1 Disorders of fructose metabolism	0.000	0.973	0.027
E74.0 Glycogen storage disease	0.000	0.973	0.027
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.973	0.027
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.973	0.027
E79.1 Lesch-Nyhan syndrome	0.000	0.973	0.027
E85.4 Organ-limited amyloidosis	0.000	0.973	0.027
E72.0 Disorders of amino-acid transport	0.000	0.973	0.027
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.973	0.027
E78.5 Hyperlipidaemia, unspecified	0.000	0.973	0.027
J00 Acute nasopharyngitis [common cold]	0.026	0.974	0.000
E73 Lactose intolerance	0.000	0.974	0.026
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.974	0.026
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.974	0.026
E72.5 Disorders of glycine metabolism	0.000	0.974	0.026
E72.4 Disorders of ornithine metabolism	0.000	0.974	0.026
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.974	0.026
E72.2 Disorders of urea cycle metabolism	0.000	0.974	0.026
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.974	0.026
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.975	0.025
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.975	0.025
E71.3 Disorders of fatty-acid metabolism	0.000	0.975	0.025
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.975	0.025
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.975	0.025
E71.0 Maple-syrup-urine disease	0.000	0.975	0.025
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.975	0.025
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.975	0.025
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.975	0.025
E76.2 Other mucopolysaccharidoses	0.000	0.975	0.025
E76.1 Mucopolysaccharidosis, type II	0.000	0.975	0.025
E76.0 Mucopolysaccharidosis, type I	0.000	0.975	0.025
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.975	0.025
E77.8 Other disorders of glycoprotein metabolism	0.000	0.975	0.025
E77.1 Defects in glycoprotein degradation	0.000	0.975	0.025
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.975	0.025
E85.8 Other amyloidosis	0.000	0.975	0.025
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.976	0.024
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.976	0.024
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.976	0.024
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.976	0.024
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.976	0.024
E70.2 Disorders of tyrosine metabolism	0.000	0.976	0.024
E70.1 Other hyperphenylalaninaemias	0.000	0.976	0.024
E70.0 Classical phenylketonuria	0.000	0.976	0.024
E23.0 Hypopituitarism	0.000	0.976	0.024
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.976	0.023
J41.1 Mucopurulent chronic bronchitis	0.000	0.976	0.023
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.977	0.023
E84.8 Cystic fibrosis with other manifestations	0.000	0.977	0.023
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.977	0.023
N84.1 Polyp of cervix uteri	0.023	0.977	0.000
E70.3 Albinism	0.000	0.977	0.023
J43 Emphysema	0.000	0.977	0.023
E85.3 Secondary systemic amyloidosis	0.000	0.977	0.023
J41.0 Simple chronic bronchitis	0.000	0.977	0.022
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.978	0.022
E75.6 Lipid storage disorder, unspecified	0.000	0.978	0.022
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.978	0.022
E75.3 Sphingolipidosis, unspecified	0.000	0.978	0.022
E75.2 Other sphingolipidosis	0.000	0.978	0.022
E75.1 Other gangliosidosis	0.000	0.978	0.022
E75.0 GM2 gangliosidosis	0.000	0.978	0.022
E21.3 Hyperparathyroidism, unspecified	0.000	0.978	0.021
E28.2 Polycystic ovarian syndrome	0.000	0.979	0.021

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations