TreeWAS – Variant ID: rs2524276

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	1.000
L40 Psoriasis	0.000	1.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	1.000
# Top node	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	1.000
L40-L45 Papulosquamous disorders	0.000	1.000
E03 Other hypothyroidism	0.000	1.000
C44 Other malignant neoplasms of skin	0.000	1.000
E10-E14 Diabetes mellitus	0.001	0.999
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.001	0.999
E10 Insulin-dependent diabetes mellitus	0.001	0.999
C44.3 Skin of other and unspecified parts of face	0.001	0.999
M06.9 Rheumatoid arthritis, unspecified	0.003	0.997
C43-C44 Melanoma and other malignant neoplasms of skin	0.003	0.997
Chapter II Neoplasms	0.004	0.996
L40.5 Arthropathic psoriasis	0.005	0.995
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.005	0.995
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.006	0.994
D50-D53 Nutritional anaemias	0.009	0.991
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.010	0.990
L57 Skin changes due to chronic exposure to nonionising radiation	0.011	0.989
Chapter I Certain infectious and parasitic diseases	0.011	0.989
M06 Other rheumatoid arthritis	0.012	0.988
D50 Iron deficiency anaemia	0.012	0.988
L00-L08 Infections of the skin and subcutaneous tissue	0.013	0.987
D50.9 Iron deficiency anaemia, unspecified	0.015	0.985
L57.0 Actinic keratosis	0.020	0.980
M05-M14 Inflammatory polyarthropathies	0.020	0.980
C44.4 Skin of scalp and neck	0.023	0.977
E10.9 Without complications	0.025	0.975
E65-E68 Obesity and other hyperalimentation	0.029	0.971
Chapter IX Diseases of the circulatory system	0.031	0.969
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.031	0.969
E10.3 With ophthalmic complications	0.033	0.967
L02 Cutaneous abscess, furuncle and carbuncle	0.033	0.967
C44.1 Skin of eyelid, including canthus	0.037	0.963
B25-B34 Other viral diseases	0.038	0.962
D60-D64 Aplastic and other anaemias	0.041	0.959
E70-E90 Metabolic disorders	0.047	0.953
B35-B49 Mycoses	0.048	0.952
E66 Obesity	0.048	0.952
I60-I69 Cerebrovascular diseases	0.048	0.952
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.051	0.949
E66.8 Other obesity	0.051	0.949
D64 Other anaemias	0.055	0.945
I20-I25 Ischaemic heart diseases	0.062	0.938
B34 Viral infection of unspecified site	0.062	0.938
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.063	0.937
B37 Candidiasis	0.065	0.935
D64.9 Anaemia, unspecified	0.065	0.935
I21 Acute myocardial infarction	0.066	0.934
L08 Other local infections of skin and subcutaneous tissue	0.067	0.933
C34 Malignant neoplasm of bronchus and lung	0.069	0.931
B37.8 Candidiasis of other sites	0.075	0.925
B34.9 Viral infection, unspecified	0.080	0.920
E87 Other disorders of fluid, electrolyte and acid-base balance	0.080	0.920
M07 Psoriatic and enteropathic arthropathies	0.083	0.917
C44.7 Skin of lower limb, including hip	0.085	0.915
I21.9 Acute myocardial infarction, unspecified	0.085	0.915
I60 Subarachnoid haemorrhage	0.094	0.906
C64-C68 Malignant neoplasms of urinary tract	0.094	0.906
Chapter VIII Diseases of the ear and mastoid process	0.094	0.906
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.094	0.906
D80-D89 Certain disorders involving the immune mechanism	0.096	0.904
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.097	0.903
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.100	0.900
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.101	0.899
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.108	0.892
C34.9 Bronchus or lung, unspecified	0.108	0.892
E06 Thyroiditis	0.109	0.891
E05 Thyrotoxicosis [hyperthyroidism]	0.110	0.890
E10.1 With ketoacidosis	0.113	0.887
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.119	0.881
I21.2 Acute transmural myocardial infarction of other sites	0.122	0.878
I21.1 Acute transmural myocardial infarction of inferior wall	0.123	0.877
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.124	0.876
E87.1 Hypo-osmolality and hyponatraemia	0.125	0.875
E50-E64 Other nutritional deficiencies	0.126	0.874
M07.3 Other psoriatic arthropathies	0.129	0.871
M06.0 Seronegative rheumatoid arthritis	0.139	0.861
R47-R49 Symptoms and signs involving speech and voice	0.139	0.861
D86 Sarcoidosis	0.140	0.860
I69 Sequelae of cerebrovascular disease	0.142	0.858
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.143	0.857
I70-I79 Diseases of arteries, arterioles and capillaries	0.145	0.855
I63 Cerebral infarction	0.147	0.853
E10.4 With neurological complications	0.147	0.853
R41 Other symptoms and signs involving cognitive functions and awareness	0.148	0.852
I67 Other cerebrovascular diseases	0.149	0.851
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.153	0.847
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.157	0.843
E89.0 Postprocedural hypothyroidism	0.163	0.837
E14 Unspecified diabetes mellitus	0.164	0.836
H65-H75 Diseases of middle ear and mastoid	0.164	0.836
C44.2 Skin of ear and external auricular canal	0.165	0.835
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.167	0.833
R41.0 Disorientation, unspecified	0.167	0.833
R47 Speech disturbances, not elsewhere classified	0.175	0.825
M45-M49 Spondylopathies	0.175	0.825
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.177	0.823
E87.2 Acidosis	0.181	0.819
M05 Seropositive rheumatoid arthritis	0.182	0.818
H72 Perforation of tympanic membrane	0.183	0.817
L20-L30 Dermatitis and eczema	0.186	0.814
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.188	0.812
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.193	0.807
E06.3 Autoimmune thyroiditis	0.194	0.806
C79 Secondary malignant neoplasm of other sites	0.194	0.806
E10.5 With peripheral circulatory complications	0.196	0.804
R41.3 Other amnesia	0.196	0.804
H72.9 Perforation of tympanic membrane, unspecified	0.197	0.803
B35 Dermatophytosis	0.198	0.802
I67.8 Other specified cerebrovascular diseases	0.198	0.802
R26 Abnormalities of gait and mobility	0.199	0.801
I73 Other peripheral vascular diseases	0.200	0.800
R47.0 Dysphasia and aphasia	0.200	0.800
E05.0 Thyrotoxicosis with diffuse goitre	0.202	0.798
M45 Ankylosing spondylitis	0.202	0.798
M07.39 Other psoriatic arthropathies (Site unspecified)	0.202	0.798
E53 Deficiency of other B group vitamins	0.202	0.797
I63.9 Cerebral infarction, unspecified	0.206	0.794
B99-B99 Other infectious diseases	0.207	0.793
D86.9 Sarcoidosis, unspecified	0.208	0.792
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.210	0.790
B37.0 Candidal stomatitis	0.210	0.790
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.210	0.790
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.210	0.790
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.215	0.785
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.218	0.782
E87.6 Hypokalaemia	0.218	0.782
I05-I09 Chronic rheumatic heart diseases	0.220	0.780
M45.X9 Ankylosing spondylitis (Site unspecified)	0.221	0.779
C67 Malignant neoplasm of bladder	0.222	0.778
L40.0 Psoriasis vulgaris	0.224	0.776
C34.1 Upper lobe, bronchus or lung	0.224	0.776
C34.3 Lower lobe, bronchus or lung	0.227	0.773
I73.0 Raynaud's syndrome	0.229	0.771
B20-B24 Human immunodeficiency virus [HIV] disease	0.229	0.771
D86.0 Sarcoidosis of lung	0.229	0.771
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.229	0.771
D55-D59 Haemolytic anaemias	0.230	0.770
H80-H83 Diseases of inner ear	0.230	0.770
R93 Abnormal findings on diagnostic imaging of other body structures	0.231	0.769
L05 Pilonidal cyst	0.232	0.768
I77 Other disorders of arteries and arterioles	0.234	0.766
M07.30 Other psoriatic arthropathies (Multiple sites)	0.239	0.761
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.242	0.758
R91 Abnormal findings on diagnostic imaging of lung	0.245	0.755
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.245	0.755
R26.8 Other and unspecified abnormalities of gait and mobility	0.246	0.754
I69.3 Sequelae of cerebral infarction	0.247	0.753
E86 Volume depletion	0.251	0.749
M95.0 Acquired deformity of nose	0.251	0.749
E10.2 With renal complications	0.252	0.748
B25 Cytomegaloviral disease	0.253	0.747
C66 Malignant neoplasm of ureter	0.253	0.747
C44.0 Skin of lip	0.253	0.747
C34.2 Middle lobe, bronchus or lung	0.254	0.746
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.254	0.746
E05.9 Thyrotoxicosis, unspecified	0.256	0.744
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.256	0.744
E53.8 Deficiency of other specified B group vitamins	0.257	0.743
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.257	0.743
E40-E46 Malnutrition	0.258	0.742
H65 Nonsuppurative otitis media	0.260	0.740
I60.9 Subarachnoid haemorrhage, unspecified	0.262	0.738
Chapter XXII Codes for special purposes	0.266	0.734
C79.8 Secondary malignant neoplasm of other specified sites	0.267	0.733
A50-A64 Infections with a predominantly sexual mode of transmission	0.268	0.732
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.270	0.730
A00-A09 Intestinal infectious diseases	0.273	0.727
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.274	0.726
E73 Lactose intolerance	0.274	0.726
I60.8 Other subarachnoid haemorrhage	0.275	0.725
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.278	0.722
M00-M03 Infectious arthropathies	0.279	0.721
R47.1 Dysarthria and anarthria	0.280	0.720
E14.9 Without complications	0.282	0.718
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.282	0.718
L40.8 Other psoriasis	0.283	0.717
L40.4 Guttate psoriasis	0.283	0.717
L40.3 Pustulosis palmaris et plantaris	0.283	0.717
L40.2 Acrodermatitis continua	0.283	0.717
L40.1 Generalised pustular psoriasis	0.283	0.717
Chapter XVI Certain conditions originating in the perinatal period	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.283	0.717
E03.5 Myxoedema coma	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.283	0.717
L44 Other papulosquamous disorders	0.283	0.717
L41 Parapsoriasis	0.283	0.717
L45 Papulosquamous disorders in diseases classified elsewhere	0.283	0.717
C65 Malignant neoplasm of renal pelvis	0.283	0.717
C44.8 Overlapping lesion of skin	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.283	0.717
Chapter V Mental and behavioural disorders	0.283	0.717
E10.8 With unspecified complications	0.284	0.716
E10.7 With multiple complications	0.284	0.716
E10.0 With coma	0.284	0.716
L56 Other acute skin changes due to ultraviolet radiation	0.285	0.715
M06.98 Rheumatoid arthritis, unspecified (Other)	0.285	0.715
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.287	0.712
L58 Radiodermatitis	0.287	0.712
L55 Sunburn	0.287	0.712
D50.8 Other iron deficiency anaemias	0.288	0.712
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.291	0.709
A30-A49 Other bacterial diseases	0.291	0.709
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.291	0.709
L57.5 Actinic granuloma	0.291	0.709
L57.3 Poikiloderma of Civatte	0.291	0.709
L57.2 Cutis rhomboidalis nuchae	0.291	0.709
L57.1 Actinic reticuloid	0.291	0.709
I77.1 Stricture of artery	0.291	0.709
B85-B89 Pediculosis, acariasis and other infestations	0.291	0.709
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.291	0.709
A75-A79 Rickettsioses	0.291	0.709
A70-A74 Other diseases caused by chlamydiae	0.291	0.709
A65-A69 Other spirochaetal diseases	0.291	0.709
A20-A28 Certain zoonotic bacterial diseases	0.291	0.709
A15-A19 Tuberculosis	0.291	0.709
M06.8 Other specified rheumatoid arthritis	0.291	0.708
M06.2 Rheumatoid bursitis	0.291	0.708
M06.1 Adult-onset Still's disease	0.291	0.708
D50.1 Sideropenic dysphagia	0.291	0.708
L04 Acute lymphadenitis	0.292	0.708
L01 Impetigo	0.292	0.708
L00 Staphylococcal scalded skin syndrome	0.292	0.708
L29 Pruritus	0.294	0.706
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.294	0.706
H72.0 Central perforation of tympanic membrane	0.296	0.704
M12 Other specific arthropathies	0.297	0.703
M09 Juvenile arthritis in diseases classified elsewhere	0.297	0.703
M08 Juvenile arthritis	0.297	0.703
D61 Other aplastic anaemias	0.297	0.703
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.298	0.702
I67.2 Cerebral atherosclerosis	0.298	0.702
E11 Non-insulin-dependent diabetes mellitus	0.299	0.701
H60-H62 Diseases of external ear	0.299	0.701
M05.9 Seropositive rheumatoid arthritis, unspecified	0.299	0.701
E80 Disorders of porphyrin and bilirubin metabolism	0.300	0.700
B50-B64 Protozoal diseases	0.302	0.697
L10-L14 Bullous disorders	0.303	0.697
E67 Other hyperalimentation	0.304	0.696
E68 Sequelae of hyperalimentation	0.304	0.696
C67.2 Lateral wall of bladder	0.305	0.695
I00-I02 Acute rheumatic fever	0.305	0.694
B65-B83 Helminthiases	0.306	0.694
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.307	0.693
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.309	0.690
B33 Other viral diseases, not elsewhere classified	0.310	0.690
B30 Viral conjunctivitis	0.310	0.690
B27 Infectious mononucleosis	0.310	0.690
B26 Mumps	0.310	0.690
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.312	0.688
R90 Abnormal findings on diagnostic imaging of central nervous system	0.314	0.686
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.314	0.686
E03.8 Other specified hypothyroidism	0.315	0.685
M14 Arthropathies in other diseases classified elsewhere	0.315	0.685
M46 Other inflammatory spondylopathies	0.316	0.684
E84 Cystic fibrosis	0.316	0.684
E79 Disorders of purine and pyrimidine metabolism	0.316	0.684
E77 Disorders of glycoprotein metabolism	0.316	0.684
E76 Disorders of glycosaminoglycan metabolism	0.316	0.684
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.316	0.684
E72 Other disorders of amino-acid metabolism	0.316	0.684
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.316	0.684
E70 Disorders of aromatic amino-acid metabolism	0.316	0.684
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.316	0.684
B90-B94 Sequelae of infectious and parasitic diseases	0.317	0.683
E74 Other disorders of carbohydrate metabolism	0.317	0.683
B48 Other mycoses, not elsewhere classified	0.317	0.683
B47 Mycetoma	0.317	0.683
B46 Zygomycosis	0.317	0.683
B45 Cryptococcosis	0.317	0.683
B43 Chromomycosis and phaeomycotic abscess	0.317	0.683
B42 Sporotrichosis	0.317	0.683
B41 Paracoccidioidomycosis	0.317	0.683
B40 Blastomycosis	0.317	0.683
B39 Histoplasmosis	0.317	0.683
B38 Coccidioidomycosis	0.317	0.683
B36 Other superficial mycoses	0.317	0.683
E66.1 Drug-induced obesity	0.317	0.682
E66.0 Obesity due to excess calories	0.317	0.682
I68 Cerebrovascular disorders in diseases classified elsewhere	0.318	0.682
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.318	0.682
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.319	0.681
C78.0 Secondary malignant neoplasm of lung	0.319	0.681
D70-D77 Other diseases of blood and blood-forming organs	0.319	0.681
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.320	0.680
C31 Malignant neoplasm of accessory sinuses	0.320	0.680
C30 Malignant neoplasm of nasal cavity and middle ear	0.320	0.680
C37 Malignant neoplasm of thymus	0.320	0.680
C33 Malignant neoplasm of trachea	0.320	0.680
Chapter VI Diseases of the nervous system	0.320	0.680
E13 Other specified diabetes mellitus	0.320	0.679
I22 Subsequent myocardial infarction	0.321	0.679
I70 Atherosclerosis	0.321	0.679
I05 Rheumatic mitral valve diseases	0.321	0.679
I62 Other nontraumatic intracranial haemorrhage	0.322	0.678
D64.4 Congenital dyserythropoietic anaemia	0.323	0.677
D64.3 Other sideroblastic anaemias	0.323	0.677
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.323	0.677
D64.1 Secondary sideroblastic anaemia due to disease	0.323	0.677
D64.0 Hereditary sideroblastic anaemia	0.323	0.677
L08.8 Other specified local infections of skin and subcutaneous tissue	0.323	0.677
R41.2 Retrograde amnesia	0.324	0.676
E10.6 With other specified complications	0.325	0.674
D64.8 Other specified anaemias	0.326	0.674
R49 Voice disturbances	0.326	0.674
C40-C41 Malignant neoplasms of bone and articular cartilage	0.327	0.673
B15-B19 Viral hepatitis	0.327	0.673
B34.8 Other viral infections of unspecified site	0.328	0.672
B34.4 Papovirus infection, unspecified	0.328	0.672
B34.3 Parvovirus infection, unspecified	0.328	0.672
B34.2 Coronavirus infection, unspecified	0.328	0.672
B34.1 Enterovirus infection, unspecified	0.328	0.672
B34.0 Adenovirus infection, unspecified	0.328	0.672
B37.7 Candidal septicaemia	0.329	0.671
B37.6 Candidal endocarditis	0.329	0.671
B37.5 Candidal meningitis	0.329	0.671
B37.2 Candidiasis of skin and nail	0.329	0.671
G35-G37 Demyelinating diseases of the central nervous system	0.330	0.670
E88 Other metabolic disorders	0.330	0.669
I21.X Presumed acute myicardial infaction (unconfirmed)	0.331	0.669
I21.3 Acute transmural myocardial infarction of unspecified site	0.331	0.669
L08.1 Erythrasma	0.331	0.669
L08.0 Pyoderma	0.331	0.669
E65 Localised adiposity	0.332	0.668
R26.2 Difficulty in walking, not elsewhere classified	0.332	0.668
C34.8 Overlapping lesion of bronchus and lung	0.332	0.668
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.333	0.666
G35 Multiple sclerosis	0.334	0.666
M60-M63 Disorders of muscles	0.334	0.666
L29.0 Pruritus ani	0.335	0.665
D52 Folate deficiency anaemia	0.336	0.664
B37.1 Pulmonary candidiasis	0.336	0.664
M11 Other crystal arthropathies	0.339	0.661
E87.4 Mixed disorder of acid-base balance	0.340	0.660
E06.9 Thyroiditis, unspecified	0.341	0.659
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.341	0.659
B35.1 Tinea unguium	0.342	0.658
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.342	0.658
I95-I99 Other and unspecified disorders of the circulatory system	0.342	0.658
R27 Other lack of coordination	0.343	0.657
M07.6 Other enteropathic arthropathies	0.343	0.657
M07.5 Arthropathy in ulcerative colitis	0.343	0.657
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.343	0.657
M07.2 Psoriatic spondylitis	0.343	0.657
M07.1 Arthritis mutilans	0.343	0.657
M07.0 Distal interphalangeal psoriatic arthropathy	0.343	0.657
H80 Otosclerosis	0.344	0.656
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.344	0.656
B99 Other and unspecified infectious diseases	0.347	0.653
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.350	0.650
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.350	0.650
I60.5 Subarachnoid haemorrhage from vertebral artery	0.350	0.650
I60.4 Subarachnoid haemorrhage from basilar artery	0.350	0.650
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.350	0.650
C68 Malignant neoplasm of other and unspecified urinary organs	0.350	0.650
L57.4 Cutis laxa senilis	0.351	0.649
D84 Other immunodeficiencies	0.351	0.648
D83 Common variable immunodeficiency	0.351	0.648
D82 Immunodeficiency associated with other major defects	0.351	0.648
D81 Combined immunodeficiencies	0.351	0.648
E55 Vitamin D deficiency	0.352	0.648
E20-E35 Disorders of other endocrine glands	0.354	0.646
C44.6 Skin of upper limb, including shoulder	0.354	0.646
R95-R99 Ill-defined and unknown causes of mortality	0.354	0.646
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.355	0.645
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.355	0.644
C76 Malignant neoplasm of other and ill-defined sites	0.356	0.644
R26.3 Immobility	0.356	0.644
H65.9 Nonsuppurative otitis media, unspecified	0.357	0.643
C38 Malignant neoplasm of heart, mediastinum and pleura	0.357	0.643
R21 Rash and other nonspecific skin eruption	0.357	0.643
C79.6 Secondary malignant neoplasm of ovary	0.360	0.640
I24 Other acute ischaemic heart diseases	0.360	0.640
E06.5 Other chronic thyroiditis	0.361	0.639
E06.4 Drug-induced thyroiditis	0.361	0.639
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.361	0.639
E06.1 Subacute thyroiditis	0.361	0.639
E06.0 Acute thyroiditis	0.361	0.639
A80-A89 Viral infections of the central nervous system	0.361	0.639
E05.5 Thyroid crisis or storm	0.362	0.638
E05.4 Thyrotoxicosis factitia	0.362	0.638
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.362	0.638
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.362	0.638
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.363	0.637
M06.3 Rheumatoid nodule	0.365	0.635
L50-L54 Urticaria and erythema	0.365	0.635
I23 Certain current complications following acute myocardial infarction	0.365	0.634
L05.0 Pilonidal cyst with abscess	0.366	0.634
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.366	0.634
I61 Intracerebral haemorrhage	0.366	0.634
B35.3 Tinea pedis	0.367	0.633
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.368	0.631
E89.8 Other postprocedural endocrine and metabolic disorders	0.368	0.631
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.368	0.631
E89.5 Postprocedural testicular hypofunction	0.368	0.631
E89.4 Postprocedural ovarian failure	0.368	0.631
E89.1 Postprocedural hypoinsulinaemia	0.368	0.631
C51-C58 Malignant neoplasms of female genital organs	0.369	0.631
E11.3 With ophthalmic complications	0.370	0.630
D53 Other nutritional anaemias	0.370	0.630
C64 Malignant neoplasm of kidney, except renal pelvis	0.373	0.627
I77.6 Arteritis, unspecified	0.373	0.627
E64 Sequelae of malnutrition and other nutritional deficiencies	0.373	0.626
E63 Other nutritional deficiencies	0.373	0.626
E56 Other vitamin deficiencies	0.373	0.626
E51 Thiamine deficiency	0.373	0.626
E50 Vitamin A deficiency	0.373	0.626
E60 Dietary zinc deficiency	0.373	0.626
E59 Dietary selenium deficiency	0.373	0.626
E58 Dietary calcium deficiency	0.373	0.626
E54 Ascorbic acid deficiency	0.373	0.626
E52 Niacin deficiency [pellagra]	0.373	0.626
M07.38 Other psoriatic arthropathies (Other)	0.375	0.624
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.375	0.624
M07.36 Other psoriatic arthropathies (Lower leg)	0.375	0.624
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.375	0.624
M07.34 Other psoriatic arthropathies (Hand)	0.375	0.624
M07.33 Other psoriatic arthropathies (Forearm)	0.375	0.624
M07.32 Other psoriatic arthropathies (Upper arm)	0.375	0.624
M07.31 Other psoriatic arthropathies (Shoulder region)	0.375	0.624
E66.2 Extreme obesity with alveolar hypoventilation	0.376	0.623
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.380	0.619
H70 Mastoiditis and related conditions	0.380	0.619
I67.0 Dissection of cerebral arteries, nonruptured	0.381	0.618
D80 Immunodeficiency with predominantly antibody defects	0.382	0.618
M06.08 Seronegative rheumatoid arthritis (Other)	0.382	0.618
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.382	0.618
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.382	0.618
M06.04 Seronegative rheumatoid arthritis (Hand)	0.382	0.618
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.382	0.618
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.382	0.618
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.382	0.618
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.382	0.617
L30 Other dermatitis	0.383	0.617
D86.3 Sarcoidosis of skin	0.384	0.616
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.384	0.616
D86.1 Sarcoidosis of lymph nodes	0.384	0.616
E87.3 Alkalosis	0.384	0.616
M46.9 Inflammatory spondylopathy, unspecified	0.384	0.615
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.385	0.615
D59 Acquired haemolytic anaemia	0.385	0.615
B24 Unspecified human immunodeficiency virus [HIV] disease	0.385	0.615
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.387	0.613
M06.4 Inflammatory polyarthropathy	0.387	0.613
B37.4 Candidiasis of other urogenital sites	0.388	0.612
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.388	0.611
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.388	0.611
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.388	0.611
R41.1 Anterograde amnesia	0.389	0.611
E89.3 Postprocedural hypopituitarism	0.389	0.610
I67.7 Cerebral arteritis, not elsewhere classified	0.390	0.610
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.390	0.610
I67.5 Moyamoya disease	0.390	0.610
I67.4 Hypertensive encephalopathy	0.390	0.610
I67.3 Progressive vascular leukoencephalopathy	0.390	0.610
C79.9 Secondary malignant neoplasm, unspecified site	0.390	0.610
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.390	0.610
E89.2 Postprocedural hypoparathyroidism	0.392	0.608
D51 Vitamin B12 deficiency anaemia	0.392	0.608
M99 Biomechanical lesions, not elsewhere classified	0.392	0.608
E27 Other disorders of adrenal gland	0.393	0.607
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.394	0.606
B37.3 Candidiasis of vulva and vagina	0.396	0.604
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.397	0.603
C44.9 Malignant neoplasm of skin, unspecified	0.397	0.602
R46 Symptoms and signs involving appearance and behaviour	0.398	0.602
E14.3 With ophthalmic complications	0.398	0.601
I71 Aortic aneurysm and dissection	0.399	0.601
A08 Viral and other specified intestinal infections	0.399	0.601
E14.8 With unspecified complications	0.400	0.600
E14.7 With multiple complications	0.400	0.600
E14.6 With other specified complications	0.400	0.600
E14.5 With peripheral circulatory complications	0.400	0.600
E14.4 With neurological complications	0.400	0.600
E14.2 Withrenal complications	0.400	0.600
E14.1 With ketoacidosis	0.400	0.600
E14.0 With coma	0.400	0.600
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.401	0.599
H68 Eustachian salpingitis and obstruction	0.401	0.599
H67 Otitis media in diseases classified elsewhere	0.401	0.599
L43 Lichen planus	0.401	0.599
C67.1 Dome of bladder	0.401	0.599
L28 Lichen simplex chronicus and prurigo	0.402	0.598
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.402	0.598
A02 Other Salmonella infections	0.402	0.598
H83 Other diseases of inner ear	0.403	0.597
E87.7 Fluid overload	0.404	0.596
B25.9 Cytomegaloviral disease, unspecified	0.406	0.594
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.406	0.594
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.406	0.593

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations