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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2524277
log Bayes Factor = 19.2656
Chromosome 6   position 31,407,579  (GRCh37) Explore rs2524277 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.002 0.998
E10-E14 Diabetes mellitus
0.000 0.003 0.997
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.005 0.995
E10 Insulin-dependent diabetes mellitus
0.000 0.006 0.994
M06 Other rheumatoid arthritis
0.000 0.006 0.994
# Top node
0.000 0.008 0.992
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.009 0.991
M05-M14 Inflammatory polyarthropathies
0.000 0.015 0.985
D50-D53 Nutritional anaemias
0.000 0.020 0.980
D60-D64 Aplastic and other anaemias
0.000 0.022 0.978
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.024 0.976
D50 Iron deficiency anaemia
0.000 0.025 0.975
E10.9 Without complications
0.000 0.026 0.974
D50.9 Iron deficiency anaemia, unspecified
0.000 0.034 0.966
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.039 0.961
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.043 0.957
D64 Other anaemias
0.000 0.046 0.954
M07 Psoriatic and enteropathic arthropathies
0.000 0.050 0.950
E10.3 With ophthalmic complications
0.000 0.051 0.949
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.053 0.947
D64.9 Anaemia, unspecified
0.000 0.061 0.939
L57.0 Actinic keratosis
0.000 0.062 0.938
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.071 0.929
M07.3 Other psoriatic arthropathies
0.000 0.076 0.924
C44.3 Skin of other and unspecified parts of face
0.000 0.090 0.910
C44 Other malignant neoplasms of skin
0.000 0.091 0.909
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.097 0.903
M06.0 Seronegative rheumatoid arthritis
0.000 0.101 0.899
D61 Other aplastic anaemias
0.000 0.103 0.897
E65-E68 Obesity and other hyperalimentation
0.000 0.109 0.891
E06 Thyroiditis
0.000 0.111 0.889
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.127 0.873
L08 Other local infections of skin and subcutaneous tissue
0.000 0.129 0.871
C44.1 Skin of eyelid, including canthus
0.000 0.130 0.870
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.131 0.869
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.132 0.868
M05 Seropositive rheumatoid arthritis
0.000 0.135 0.865
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.141 0.859
E50-E64 Other nutritional deficiencies
0.000 0.144 0.856
C44.4 Skin of scalp and neck
0.000 0.146 0.854
Chapter I Certain infectious and parasitic diseases
0.000 0.150 0.850
Chapter VIII Diseases of the ear and mastoid process
0.000 0.154 0.846
D61.9 Aplastic anaemia, unspecified
0.000 0.161 0.839
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.161 0.839
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.164 0.836
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.168 0.832
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.171 0.829
C44.7 Skin of lower limb, including hip
0.000 0.172 0.828
E14 Unspecified diabetes mellitus
0.000 0.173 0.826
L40.0 Psoriasis vulgaris
0.000 0.180 0.820
E66 Obesity
0.000 0.180 0.820
C44.2 Skin of ear and external auricular canal
0.000 0.187 0.813
E40-E46 Malnutrition
0.000 0.190 0.810
E06.3 Autoimmune thyroiditis
0.000 0.193 0.807
E66.8 Other obesity
0.000 0.195 0.805
B35-B49 Mycoses
0.000 0.200 0.800
H65-H75 Diseases of middle ear and mastoid
0.000 0.206 0.794
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.207 0.793
E10.1 With ketoacidosis
0.000 0.207 0.793
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.214 0.786
C44.6 Skin of upper limb, including shoulder
0.000 0.214 0.786
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.216 0.784
D80-D89 Certain disorders involving the immune mechanism
0.000 0.219 0.781
E70-E90 Metabolic disorders
0.000 0.219 0.781
B37 Candidiasis
0.000 0.219 0.781
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.220 0.780
B25-B34 Other viral diseases
0.000 0.223 0.777
H72 Perforation of tympanic membrane
0.000 0.226 0.774
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.227 0.772
B37.8 Candidiasis of other sites
0.000 0.231 0.769
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.232 0.768
E53 Deficiency of other B group vitamins
0.000 0.235 0.765
E10.4 With neurological complications
0.000 0.238 0.762
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.238 0.762
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.241 0.759
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.243 0.757
L20-L30 Dermatitis and eczema
0.000 0.246 0.754
M95.0 Acquired deformity of nose
0.000 0.249 0.751
E03.8 Other specified hypothyroidism
0.000 0.250 0.750
E10.5 With peripheral circulatory complications
0.000 0.259 0.741
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.267 0.733
Chapter VII Diseases of the eye and adnexa
0.000 0.272 0.728
E14.9 Without complications
0.000 0.273 0.727
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.276 0.724
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.277 0.723
M14 Arthropathies in other diseases classified elsewhere
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
D55-D59 Haemolytic anaemias
0.000 0.286 0.713
E10.8 With unspecified complications
0.000 0.287 0.713
E10.7 With multiple complications
0.000 0.287 0.713
E10.6 With other specified complications
0.000 0.287 0.713
E10.2 With renal complications
0.000 0.287 0.713
E10.0 With coma
0.000 0.287 0.713
M06.8 Other specified rheumatoid arthritis
0.000 0.287 0.713
M06.2 Rheumatoid bursitis
0.000 0.287 0.713
M06.1 Adult-onset Still's disease
0.000 0.287 0.713
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.288 0.712
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.289 0.711
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.290 0.710
B34 Viral infection of unspecified site
0.000 0.292 0.708
M12 Other specific arthropathies
0.000 0.294 0.706
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.294 0.706
M08 Juvenile arthritis
0.000 0.294 0.706
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.296 0.704
H65 Nonsuppurative otitis media
0.000 0.296 0.704
D53 Other nutritional anaemias
0.000 0.297 0.703
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.299 0.701
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.299 0.701
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.300 0.700
L58 Radiodermatitis
0.000 0.300 0.700
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.300 0.700
L55 Sunburn
0.000 0.300 0.700
E53.8 Deficiency of other specified B group vitamins
0.000 0.300 0.700
D50.1 Sideropenic dysphagia
0.000 0.301 0.699
L05 Pilonidal cyst
0.000 0.302 0.698
M00-M03 Infectious arthropathies
0.000 0.303 0.697
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.303 0.697
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.306 0.694
E89.0 Postprocedural hypothyroidism
0.000 0.306 0.694
Chapter XXII Codes for special purposes
0.000 0.308 0.691
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.311 0.689
L57.5 Actinic granuloma
0.000 0.311 0.689
L57.4 Cutis laxa senilis
0.000 0.311 0.689
L57.3 Poikiloderma of Civatte
0.000 0.311 0.689
L57.2 Cutis rhomboidalis nuchae
0.000 0.311 0.689
L57.1 Actinic reticuloid
0.000 0.311 0.689
L04 Acute lymphadenitis
0.000 0.314 0.686
L01 Impetigo
0.000 0.314 0.686
L00 Staphylococcal scalded skin syndrome
0.000 0.314 0.686
H02 Other disorders of eyelid
0.000 0.315 0.685
L10-L14 Bullous disorders
0.000 0.315 0.685
D64.4 Congenital dyserythropoietic anaemia
0.000 0.316 0.684
D64.3 Other sideroblastic anaemias
0.000 0.316 0.684
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.316 0.684
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.316 0.684
D64.0 Hereditary sideroblastic anaemia
0.000 0.316 0.684
E20-E35 Disorders of other endocrine glands
0.000 0.319 0.681
M07.6 Other enteropathic arthropathies
0.000 0.319 0.681
M07.5 Arthropathy in ulcerative colitis
0.000 0.319 0.681
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.319 0.681
M07.2 Psoriatic spondylitis
0.000 0.319 0.681
M07.1 Arthritis mutilans
0.000 0.319 0.681
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.319 0.681
C44.0 Skin of lip
0.000 0.320 0.680
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.321 0.679
D51 Vitamin B12 deficiency anaemia
0.000 0.323 0.677
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.324 0.676
E11 Non-insulin-dependent diabetes mellitus
0.000 0.325 0.675
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.326 0.674
E46 Unspecified protein-energy malnutrition
0.000 0.326 0.674
D86 Sarcoidosis
0.000 0.329 0.671
M11 Other crystal arthropathies
0.000 0.330 0.670
H02.0 Entropion and trichiasis of eyelid
0.000 0.334 0.666
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.335 0.665
M06.3 Rheumatoid nodule
0.000 0.336 0.664
M07.38 Other psoriatic arthropathies (Other)
0.000 0.337 0.663
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.337 0.663
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.337 0.663
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.337 0.663
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.337 0.663
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.337 0.663
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.337 0.663
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.337 0.663
E05.9 Thyrotoxicosis, unspecified
0.000 0.339 0.661
H02.1 Ectropion of eyelid
0.000 0.340 0.660
B34.9 Viral infection, unspecified
0.000 0.341 0.659
M06.4 Inflammatory polyarthropathy
0.000 0.341 0.658
D50.8 Other iron deficiency anaemias
0.000 0.348 0.652
C44.8 Overlapping lesion of skin
0.000 0.348 0.652
D64.8 Other specified anaemias
0.000 0.348 0.651
D52 Folate deficiency anaemia
0.000 0.349 0.650
E27 Other disorders of adrenal gland
0.000 0.349 0.650
E06.9 Thyroiditis, unspecified
0.000 0.352 0.648
B99-B99 Other infectious diseases
0.000 0.352 0.648
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.352 0.647
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.353 0.647
H72.0 Central perforation of tympanic membrane
0.000 0.354 0.646
L29 Pruritus
0.000 0.354 0.646
M60-M63 Disorders of muscles
0.000 0.354 0.646
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.355 0.644
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.355 0.644
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.355 0.644
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.355 0.644
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.355 0.644
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.355 0.644
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.355 0.644
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.355 0.644
B37.0 Candidal stomatitis
0.000 0.356 0.644
D61.8 Other specified aplastic anaemias
0.000 0.357 0.643
D61.3 Idiopathic aplastic anaemia
0.000 0.357 0.643
D61.2 Aplastic anaemia due to other external agents
0.000 0.357 0.643
D61.1 Drug-induced aplastic anaemia
0.000 0.357 0.643
D61.0 Constitutional aplastic anaemia
0.000 0.357 0.643
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.361 0.639
E67 Other hyperalimentation
0.000 0.361 0.639
E68 Sequelae of hyperalimentation
0.000 0.361 0.639
E06.5 Other chronic thyroiditis
0.000 0.362 0.638
E06.4 Drug-induced thyroiditis
0.000 0.362 0.638
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.362 0.638
E06.1 Subacute thyroiditis
0.000 0.362 0.638
E06.0 Acute thyroiditis
0.000 0.362 0.638
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.363 0.637
M80-M85 Disorders of bone density and structure
0.002 0.363 0.635
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.363 0.636
E13 Other specified diabetes mellitus
0.000 0.368 0.632
H60-H62 Diseases of external ear
0.000 0.369 0.631
E86 Volume depletion
0.000 0.375 0.625
L08.1 Erythrasma
0.000 0.376 0.624
L08.0 Pyoderma
0.000 0.376 0.624
H65.9 Nonsuppurative otitis media, unspecified
0.000 0.376 0.624
E05.5 Thyroid crisis or storm
0.000 0.377 0.623
E05.4 Thyrotoxicosis factitia
0.000 0.377 0.623
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.377 0.623
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.377 0.623
M91-M94 Chondropathies
0.000 0.378 0.622
M05.8 Other seropositive rheumatoid arthritis
0.000 0.379 0.620
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.379 0.620
M05.2 Rheumatoid vasculitis
0.000 0.379 0.620
M05.1 Rheumatoid lung disease
0.000 0.379 0.620
M05.0 Felty's syndrome
0.000 0.379 0.620
E65 Localised adiposity
0.000 0.385 0.615
M45-M49 Spondylopathies
0.000 0.385 0.615
B35 Dermatophytosis
0.000 0.386 0.614
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.386 0.614
E63 Other nutritional deficiencies
0.000 0.386 0.614
E56 Other vitamin deficiencies
0.000 0.386 0.614
E51 Thiamine deficiency
0.000 0.386 0.614
E50 Vitamin A deficiency
0.000 0.386 0.614
E60 Dietary zinc deficiency
0.000 0.386 0.614
E59 Dietary selenium deficiency
0.000 0.386 0.614
E58 Dietary calcium deficiency
0.000 0.386 0.614
E54 Ascorbic acid deficiency
0.000 0.386 0.614
E52 Niacin deficiency [pellagra]
0.000 0.386 0.614
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.387 0.613
E73 Lactose intolerance
0.000 0.388 0.612
B25 Cytomegaloviral disease
0.000 0.389 0.611
L43 Lichen planus
0.000 0.390 0.609
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.391 0.609
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.391 0.609
A75-A79 Rickettsioses
0.000 0.391 0.609
A70-A74 Other diseases caused by chlamydiae
0.000 0.391 0.609
A65-A69 Other spirochaetal diseases
0.000 0.391 0.609
A20-A28 Certain zoonotic bacterial diseases
0.000 0.391 0.609
A15-A19 Tuberculosis
0.000 0.391 0.609
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.391 0.609
E55 Vitamin D deficiency
0.000 0.396 0.604
H53-H54 Visual disturbances and blindness
0.000 0.397 0.603
E11.3 With ophthalmic complications
0.000 0.398 0.602
M80 Osteoporosis with pathological fracture
0.001 0.400 0.600
M99 Biomechanical lesions, not elsewhere classified
0.000 0.400 0.600
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.400 0.599
E27.1 Primary adrenocortical insufficiency
0.000 0.402 0.598
B65-B83 Helminthiases
0.000 0.403 0.597
L42 Pityriasis rosea
0.000 0.406 0.594
E14.8 With unspecified complications
0.000 0.407 0.593
E14.7 With multiple complications
0.000 0.407 0.593
E14.6 With other specified complications
0.000 0.407 0.593
E14.5 With peripheral circulatory complications
0.000 0.407 0.593
E14.4 With neurological complications
0.000 0.407 0.593
E14.2 Withrenal complications
0.000 0.407 0.593
E14.1 With ketoacidosis
0.000 0.407 0.593
E14.0 With coma
0.000 0.407 0.593
L29.0 Pruritus ani
0.000 0.408 0.592
A80-A89 Viral infections of the central nervous system
0.000 0.408 0.592
H30-H36 Disorders of choroid and retina
0.000 0.409 0.591
E61 Deficiency of other nutrient elements
0.000 0.409 0.591
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.410 0.590
B50-B64 Protozoal diseases
0.000 0.411 0.589
E66.1 Drug-induced obesity
0.000 0.412 0.588
E66.0 Obesity due to excess calories
0.000 0.412 0.588
Chapter II Neoplasms
0.000 0.413 0.587
D86.0 Sarcoidosis of lung
0.000 0.416 0.584
E07 Other disorders of thyroid
0.000 0.416 0.584
L05.0 Pilonidal cyst with abscess
0.000 0.416 0.584
H73 Other disorders of tympanic membrane
0.000 0.416 0.584
H40-H42 Glaucoma
0.000 0.416 0.584
E80.4 Gilbert's syndrome
0.000 0.418 0.582
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.419 0.581
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.419 0.581
E45 Retarded development following protein-energy malnutrition
0.000 0.419 0.581
E43 Unspecified severe protein-energy malnutrition
0.000 0.419 0.581
E42 Marasmic kwashiorkor
0.000 0.419 0.581
E41 Nutritional marasmus
0.000 0.419 0.581
E40 Kwashiorkor
0.000 0.419 0.581
B15-B19 Viral hepatitis
0.000 0.420 0.580
L28 Lichen simplex chronicus and prurigo
0.000 0.424 0.576
H80-H83 Diseases of inner ear
0.000 0.424 0.576
L50-L54 Urticaria and erythema
0.000 0.425 0.575
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.426 0.574
B48 Other mycoses, not elsewhere classified
0.000 0.426 0.574
B47 Mycetoma
0.000 0.426 0.574
B46 Zygomycosis
0.000 0.426 0.574
B45 Cryptococcosis
0.000 0.426 0.574
B43 Chromomycosis and phaeomycotic abscess
0.000 0.426 0.574
B42 Sporotrichosis
0.000 0.426 0.574
B41 Paracoccidioidomycosis
0.000 0.426 0.574
B40 Blastomycosis
0.000 0.426 0.574
B39 Histoplasmosis
0.000 0.426 0.574
B38 Coccidioidomycosis
0.000 0.426 0.574
B36 Other superficial mycoses
0.000 0.426 0.574
M45 Ankylosing spondylitis
0.000 0.427 0.573
H36 Retinal disorders in diseases classified elsewhere
0.000 0.430 0.570
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.431 0.569
H68 Eustachian salpingitis and obstruction
0.000 0.431 0.569
H67 Otitis media in diseases classified elsewhere
0.000 0.431 0.569
B37.3 Candidiasis of vulva and vagina
0.000 0.431 0.569
D80 Immunodeficiency with predominantly antibody defects
0.000 0.433 0.567
H70 Mastoiditis and related conditions
0.000 0.435 0.565
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.000 0.436 0.564
M95.8 Other specified acquired deformities of musculoskeletal system
0.000 0.436 0.564
M95.5 Acquired deformity of pelvis
0.000 0.436 0.564
M95.4 Acquired deformity of chest and rib
0.000 0.436 0.564
M95.3 Acquired deformity of neck
0.000 0.436 0.564
M95.2 Other acquired deformity of head
0.000 0.436 0.564
M95.1 Cauliflower ear
0.000 0.436 0.564
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.439 0.561
H65.4 Other chronic nonsuppurative otitis media
0.000 0.440 0.560
D84 Other immunodeficiencies
0.000 0.440 0.560
D83 Common variable immunodeficiency
0.000 0.440 0.560
D82 Immunodeficiency associated with other major defects
0.000 0.440 0.560
D81 Combined immunodeficiencies
0.000 0.440 0.560
E84 Cystic fibrosis
0.000 0.440 0.560
E79 Disorders of purine and pyrimidine metabolism
0.000 0.440 0.560
E77 Disorders of glycoprotein metabolism
0.000 0.440 0.560
E76 Disorders of glycosaminoglycan metabolism
0.000 0.440 0.560
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.440 0.560
E72 Other disorders of amino-acid metabolism
0.000 0.440 0.560
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.440 0.560
E70 Disorders of aromatic amino-acid metabolism
0.000 0.440 0.560
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.440 0.560
B37.7 Candidal septicaemia
0.000 0.440 0.560
B37.6 Candidal endocarditis
0.000 0.440 0.560
B37.5 Candidal meningitis
0.000 0.440 0.560
B37.2 Candidiasis of skin and nail
0.000 0.440 0.560
B37.1 Pulmonary candidiasis
0.000 0.440 0.560
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.441 0.559
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.441 0.559
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.441 0.559
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.441 0.559
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.441 0.559
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.441 0.559
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.441 0.559
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.441 0.559
D62 Acute posthaemorrhagic anaemia
0.000 0.441 0.559
H02.6 Xanthelasma of eyelid
0.000 0.442 0.558
Chapter VI Diseases of the nervous system
0.000 0.442 0.558
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.443 0.557
B24 Unspecified human immunodeficiency virus [HIV] disease
0.000 0.443 0.557
B33 Other viral diseases, not elsewhere classified
0.000 0.443 0.557
B30 Viral conjunctivitis
0.000 0.443 0.557
B27 Infectious mononucleosis
0.000 0.443 0.557
B26 Mumps
0.000 0.443 0.557
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.444 0.555
H36.0 Diabetic retinopathy
0.000 0.445 0.555
H72.1 Attic perforation of tympanic membrane
0.000 0.445 0.555
M10 Gout
0.000 0.446 0.554
D86.9 Sarcoidosis, unspecified
0.000 0.448 0.552
E53.9 Vitamin B deficiency, unspecified
0.000 0.451 0.548
E53.1 Pyridoxine deficiency
0.000 0.451 0.548
E53.0 Riboflavin deficiency
0.000 0.451 0.548
H05 Disorders of orbit
0.000 0.451 0.549
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.456 0.544
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.457 0.543
L25 Unspecified contact dermatitis
0.000 0.459 0.541
L24 Irritant contact dermatitis
0.000 0.459 0.541
L23 Allergic contact dermatitis
0.000 0.459 0.541
L21 Seborrhoeic dermatitis
0.000 0.459 0.541
L26 Exfoliative dermatitis
0.000 0.459 0.541
L22 Diaper [napkin] dermatitis
0.000 0.459 0.541
E74 Other disorders of carbohydrate metabolism
0.000 0.460 0.540
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.460 0.540
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.460 0.540
E14.3 With ophthalmic complications
0.000 0.461 0.539
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.462 0.537
H02.5 Other disorders affecting eyelid function
0.000 0.463 0.537
D59 Acquired haemolytic anaemia
0.000 0.464 0.536
H65.2 Chronic serous otitis media
0.000 0.466 0.534
B37.4 Candidiasis of other urogenital sites
0.000 0.466 0.534
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.468 0.532
G35 Multiple sclerosis
0.000 0.470 0.530
Chapter IX Diseases of the circulatory system
0.000 0.474 0.526
M14.6 Neuropathic arthropathy
0.000 0.475 0.525
H53 Visual disturbances
0.000 0.476 0.524
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.476 0.524
H69 Other disorders of Eustachian tube
0.000 0.477 0.523
L20 Atopic dermatitis
0.000 0.477 0.523
B49 Unspecified mycosis
0.000 0.477 0.522
E11.2 With renal complications
0.000 0.479 0.521
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.480 0.519
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.480 0.519
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.480 0.519
E89.5 Postprocedural testicular hypofunction
0.000 0.480 0.519
E89.4 Postprocedural ovarian failure
0.000 0.480 0.519
E89.1 Postprocedural hypoinsulinaemia
0.000 0.480 0.519
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.481 0.518
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.481 0.518
M00 Pyogenic arthritis
0.000 0.482 0.518
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.486 0.514
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.486 0.514
M14.4 Arthropathy in amyloidosis
0.000 0.486 0.514
M14.3 Lipoid dermatoarthritis
0.000 0.486 0.514
M14.2 Diabetic arthropathy
0.000 0.486 0.514
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.486 0.514
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
H72.8 Other perforations of tympanic membrane
0.000 0.487 0.513
L41.9 Parapsoriasis, unspecified
0.000 0.487 0.513
L41.8 Other parapsoriasis
0.000 0.487 0.513
L41.5 Retiform parapsoriasis
0.000 0.487 0.513
L41.4 Large plaque parapsoriasis
0.000 0.487 0.513
L41.3 Small plaque parapsoriasis
0.000 0.487 0.513
L41.2 Lymphomatoid papulosis
0.000 0.487 0.513
L41.1 Pityriasis lichenoides chronica
0.000 0.487 0.513
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.487 0.513
L44.9 Papulosquamous disorder, unspecified
0.000 0.487 0.513
L44.8 Other specified papulosquamous disorders
0.000 0.487 0.513
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.487 0.513
L44.3 Lichen ruber moniliformis
0.000 0.487 0.513
L44.2 Lichen striatus
0.000 0.487 0.513
L44.1 Lichen nitidus
0.000 0.487 0.513
L44.0 Pityriasis rubra pilaris
0.000 0.487 0.513
E87.2 Acidosis
0.000 0.487 0.513
E12.9 Without complications
0.000 0.487 0.512
E12.8 With unspecified complications
0.000 0.487 0.512
E12.7 With multiple complications
0.000 0.487 0.512
E12.6 With other specified complications
0.000 0.487 0.512
E12.5 With peripheral circulatory complications
0.000 0.487 0.512
E12.4 With neurological complications
0.000 0.487 0.512
E12.3 With ophthalmic complications
0.000 0.487 0.512
E12.2 With renal complications
0.000 0.487 0.512
E12.1 With ketoacidosis
0.000 0.487 0.512
E12.0 With coma
0.000 0.487 0.512
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.488 0.512
D57 Sickle-cell disorders
0.000 0.488 0.512
D56 Thalassaemia
0.000 0.488 0.512
D55 Anaemia due to enzyme disorders
0.000 0.488 0.512
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.489 0.511
M06.18 Adult-onset Still's disease (Other)
0.000 0.489 0.511
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.489 0.511
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.489 0.511
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.489 0.511
M06.14 Adult-onset Still's disease (Hand)
0.000 0.489 0.511
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.489 0.511
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.489 0.511
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.489 0.511
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.489 0.511
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.489 0.511
M06.28 Rheumatoid bursitis (Other)
0.000 0.489 0.511
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.489 0.511
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.489 0.511
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.489 0.511
M06.24 Rheumatoid bursitis (Hand)
0.000 0.489 0.511
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.489 0.511
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.489 0.511
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.489 0.511
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.489 0.511
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.489 0.511
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.489 0.511
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.489 0.511
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.489 0.511
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.489 0.511
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.489 0.511
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.489 0.511
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.489 0.511
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.489 0.511
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.489 0.511

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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