TreeWAS – Variant ID: rs2570467

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E21.3 Hyperparathyroidism, unspecified	0.203	0.797	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.084	0.916	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.074	0.926	0.000
E21.4 Other specified disorders of parathyroid gland	0.066	0.934	0.000
E21.2 Other hyperparathyroidism	0.062	0.937	0.000
G47.3 Sleep apnoea	0.046	0.954	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.045	0.955	0.000
E21.0 Primary hyperparathyroidism	0.034	0.966	0.000
G47 Sleep disorders	0.019	0.981	0.000
G47.4 Narcolepsy and cataplexy	0.016	0.984	0.000
G47.2 Disorders of the sleep-wake schedule	0.015	0.985	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.987	0.013
G47.1 Disorders of excessive somnolence [hypersomnias]	0.013	0.987	0.000
K50.1 Crohn's disease of large intestine	0.000	0.987	0.013
G47.9 Sleep disorder, unspecified	0.013	0.987	0.000
E20-E35 Disorders of other endocrine glands	0.013	0.987	0.000
G47.8 Other sleep disorders	0.012	0.988	0.000
E29 Testicular dysfunction	0.012	0.988	0.000
E32 Diseases of thymus	0.011	0.989	0.000
E29.1 Testicular hypofunction	0.011	0.989	0.000
D86.0 Sarcoidosis of lung	0.000	0.989	0.011
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.011	0.989	0.000
E23 Hypofunction and other disorders of pituitary gland	0.010	0.990	0.000
E31 Polyglandular dysfunction	0.010	0.990	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.990	0.010
E28 Ovarian dysfunction	0.010	0.990	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.009	0.991	0.000
E30 Disorders of puberty, not elsewhere classified	0.009	0.991	0.000
E23.2 Diabetes insipidus	0.009	0.991	0.000
E32.9 Disease of thymus, unspecified	0.009	0.991	0.000
E24 Cushing's syndrome	0.009	0.991	0.000
E32.8 Other diseases of thymus	0.009	0.991	0.000
E25 Adrenogenital disorders	0.009	0.991	0.000
E31.0 Autoimmune polyglandular failure	0.009	0.991	0.000
E29.9 Testicular dysfunction, unspecified	0.008	0.991	0.000
E29.8 Other testicular dysfunction	0.008	0.991	0.000
E29.0 Testicular hyperfunction	0.008	0.991	0.000
E28.3 Primary ovarian failure	0.009	0.991	0.000
R56.8 Other and unspecified convulsions	0.000	0.992	0.008
M88.9 Paget's disease of bone, unspecified	0.000	0.992	0.008
E32.1 Abscess of thymus	0.008	0.992	0.000
E32.0 Persistent hyperplasia of thymus	0.008	0.992	0.000
E23.6 Other disorders of pituitary gland	0.008	0.992	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.008	0.992	0.000
E23.1 Drug-induced hypopituitarism	0.008	0.992	0.000
E31.9 Polyglandular dysfunction, unspecified	0.008	0.992	0.000
E31.8 Other polyglandular dysfunction	0.008	0.992	0.000
E31.1 Polyglandular hyperfunction	0.008	0.992	0.000
E20 Hypoparathyroidism	0.007	0.992	0.000
E23.0 Hypopituitarism	0.008	0.992	0.000
E26 Hyperaldosteronism	0.007	0.992	0.000
I72.3 Aneurysm of iliac artery	0.008	0.992	0.000
E34 Other endocrine disorders	0.007	0.992	0.000
E28.9 Ovarian dysfunction, unspecified	0.007	0.993	0.000
E28.8 Other ovarian dysfunction	0.007	0.993	0.000
E28.1 Androgen excess	0.007	0.993	0.000
E28.0 Oestrogen excess	0.007	0.993	0.000
E24.8 Other Cushing's syndrome	0.007	0.993	0.000
E23.7 Disorder of pituitary gland, unspecified	0.007	0.993	0.000
E30.9 Disorder of puberty, unspecified	0.007	0.993	0.000
E30.8 Other disorders of puberty	0.007	0.993	0.000
E30.1 Precocious puberty	0.007	0.993	0.000
E30.0 Delayed puberty	0.007	0.993	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.007	0.993	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.007	0.993	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.007	0.993	0.000
D86 Sarcoidosis	0.000	0.993	0.007
E24.9 Cushing's syndrome, unspecified	0.007	0.993	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.007	0.993	0.000
E24.3 Ectopic ACTH syndrome	0.007	0.993	0.000
E24.1 Nelson's syndrome	0.007	0.993	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.993	0.007
E24.2 Drug-induced Cushing's syndrome	0.006	0.993	0.000
E28.2 Polycystic ovarian syndrome	0.007	0.993	0.000
E25.9 Adrenogenital disorder, unspecified	0.006	0.993	0.000
E25.8 Other adrenogenital disorders	0.006	0.993	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.000	0.994	0.006
M88.98 Paget's disease of bone, unspecified (Other)	0.000	0.994	0.006
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.000	0.994	0.006
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.000	0.994	0.006
M88.94 Paget's disease of bone, unspecified (Hand)	0.000	0.994	0.006
M88.93 Paget's disease of bone, unspecified (Forearm)	0.000	0.994	0.006
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.000	0.994	0.006
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.000	0.994	0.006
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.994	0.006
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.994	0.006
E24.0 Pituitary-dependent Cushing's disease	0.006	0.994	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.006	0.994	0.000
E34.3 Short stature, not elsewhere classified	0.006	0.994	0.000
E20.8 Other hypoparathyroidism	0.006	0.994	0.000
E20.1 Pseudohypoparathyroidism	0.006	0.994	0.000
E20.0 Idiopathic hypoparathyroidism	0.006	0.994	0.000
M35.3 Polymyalgia rheumatica	0.000	0.994	0.006
I72.9 Aneurysm of unspecified site	0.006	0.994	0.000
E34.9 Endocrine disorder, unspecified	0.006	0.994	0.000
E26.9 Hyperaldosteronism, unspecified	0.005	0.994	0.000
E26.8 Other hyperaldosteronism	0.005	0.994	0.000
E26.1 Secondary hyperaldosteronism	0.005	0.994	0.000
E34.5 Androgen resistance syndrome	0.005	0.994	0.000
E34.4 Constitutional tall stature	0.005	0.994	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.005	0.994	0.000
E34.1 Other hypersecretion of intestinal hormones	0.005	0.994	0.000
I72 Other aneurysm	0.006	0.994	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.994	0.006
S22.0 Fracture of thoracic vertebra	0.000	0.995	0.005
M35 Other systemic involvement of connective tissue	0.000	0.995	0.005
I72.2 Aneurysm of renal artery	0.005	0.995	0.000
E34.8 Other specified endocrine disorders	0.005	0.995	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.995	0.005
M35.7 Hypermobility syndrome	0.000	0.995	0.005
M35.1 Other overlap syndromes	0.000	0.995	0.005
D86.3 Sarcoidosis of skin	0.000	0.995	0.004
I72.0 Aneurysm of carotid artery	0.005	0.995	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.996	0.004
K50 Crohn's disease [regional enteritis]	0.000	0.996	0.004
I72.6 Aneurysm and dissection of vertebral artery	0.004	0.996	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.004	0.996	0.000
K50.0 Crohn's disease of small intestine	0.000	0.996	0.004
M35.2 Behcet's disease	0.000	0.996	0.004
I72.1 Aneurysm of artery of upper extremity	0.004	0.996	0.000
A63.0 Anogenital (venereal) warts	0.000	0.996	0.004
S22.01 Fracture of thoracic vertebra (open)	0.000	0.996	0.004
M88 Paget's disease of bone [osteitis deformans]	0.000	0.996	0.004
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.996	0.004
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.996	0.004
M35.5 Multifocal fibrosclerosis	0.000	0.996	0.004
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.996	0.004
E34.0 Carcinoid syndrome	0.004	0.996	0.000
E20.9 Hypoparathyroidism, unspecified	0.004	0.996	0.000
I72.4 Aneurysm of artery of lower extremity	0.004	0.996	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.000	0.996	0.004
M35.8 Other specified systemic involvement of connective tissue	0.000	0.996	0.004
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.000	0.996	0.004
E26.0 Primary hyperaldosteronism	0.003	0.996	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.996	0.004
B00.1 Herpesviral vesicular dermatitis	0.000	0.996	0.004
Q21.1 Atrial septal defect	0.000	0.996	0.004
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.000	0.996	0.004
E22 Hyperfunction of pituitary gland	0.003	0.997	0.001
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.997	0.003
I72.8 Aneurysm of other specified arteries	0.003	0.997	0.000
H53.9 Visual disturbance, unspecified	0.000	0.997	0.003
M88.8 Paget's disease of other bones	0.000	0.997	0.003
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.997	0.003
R56 Convulsions, not elsewhere classified	0.000	0.997	0.003
R63.1 Polydipsia	0.003	0.997	0.000
M88.0 Paget's disease of skull	0.000	0.997	0.003
K56.6 Other and unspecified intestinal obstruction	0.000	0.997	0.003
B00 Herpesviral [herpes simplex] infections	0.000	0.997	0.003
B00.4 Herpesviral encephalitis	0.000	0.997	0.003
B00.5 Herpesviral ocular disease	0.000	0.997	0.003
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.997	0.003
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.003	0.997	0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.000	0.997	0.003
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.997	0.001
E22.8 Other hyperfunction of pituitary gland	0.002	0.997	0.001
G96.0 Cerebrospinal fluid leak	0.000	0.997	0.003
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.997	0.003
M88.89 Paget's disease of other bones (Site unspecified)	0.000	0.997	0.002
M88.88 Paget's disease of other bones (Other)	0.000	0.997	0.002
M88.87 Paget's disease of other bones (Ankle and foot)	0.000	0.997	0.002
M88.86 Paget's disease of other bones (Lower leg)	0.000	0.997	0.002
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.000	0.997	0.002
M88.84 Paget's disease of other bones (Hand)	0.000	0.997	0.002
M88.83 Paget's disease of other bones (Forearm)	0.000	0.997	0.002
M88.82 Paget's disease of other bones (Upper arm)	0.000	0.997	0.002
M88.81 Paget's disease of other bones (Shoulder region)	0.000	0.997	0.002
M88.80 Paget's disease of other bones (Multiple sites)	0.000	0.997	0.002
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.997	0.003
K50.9 Crohn's disease, unspecified	0.000	0.997	0.003
D80-D89 Certain disorders involving the immune mechanism	0.000	0.997	0.003
M88.09 Paget's disease of skull-Site unspec	0.000	0.998	0.002
M88.08 Paget's disease of skull-Other	0.000	0.998	0.002
M88.07 Paget's disease of skull-Ankle/Foot	0.000	0.998	0.002
M88.06 Paget's disease of skull-Lower Leg	0.000	0.998	0.002
M88.05 Paget's disease of skull-Pelvic/Thigh	0.000	0.998	0.002
M88.04 Paget's disease of skull-Hand	0.000	0.998	0.002
M88.03 Paget's disease of skull-Forearm	0.000	0.998	0.002
M88.02 Paget's disease of skull-Upper arm	0.000	0.998	0.002
M88.01 Paget's disease of skull-Shldr region	0.000	0.998	0.002
M41.86 Other forms of scoliosis (Lumbar region)	0.002	0.998	0.000
R25.2 Cramp and spasm	0.000	0.998	0.002
B00.8 Other forms of herpesviral infection	0.000	0.998	0.002
B00.7 Disseminated herpesviral disease	0.000	0.998	0.002
B00.0 Eczema herpeticum	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.000	0.998	0.002
R56.0 Febrile convulsions	0.000	0.998	0.002
B00.3 Herpesviral meningitis	0.000	0.998	0.002
D69.6 Thrombocytopenia, unspecified	0.002	0.998	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.998	0.002
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
I49.8 Other specified cardiac arrhythmias	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.000	0.998	0.002
B35.1 Tinea unguium	0.002	0.998	0.000
E27 Other disorders of adrenal gland	0.002	0.998	0.000
M88.00 Paget's disease of skull-Mult sites	0.000	0.998	0.002
B00.9 Herpesviral infection, unspecified	0.000	0.998	0.002
K29.1 Other acute gastritis	0.000	0.998	0.002
H20.9 Iridocyclitis, unspecified	0.000	0.998	0.002
N30.9 Cystitis, unspecified	0.000	0.998	0.002
K35.2 Acute appendicitis with generalized peritonitis	0.002	0.998	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.998	0.002
D81 Combined immunodeficiencies	0.000	0.998	0.002
M86.9 Osteomyelitis, unspecified	0.000	0.998	0.002
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.998	0.002
K35.1 Acute appendicitis with peritoneal abscess	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.998	0.002
D03.4 Melanoma in situ of scalp and neck	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.001	0.998	0.001
E22.0 Acromegaly and pituitary gigantism	0.001	0.998	0.001
K35.9 Acute appendicitis, unspecified	0.002	0.998	0.000
M87.2 Osteonecrosis due to previous trauma	0.002	0.998	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.998	0.002
S81.8 Open wound of other parts of lower leg	0.000	0.998	0.002
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.998	0.002
D83 Common variable immunodeficiency	0.000	0.998	0.002
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
H26.4 After-cataract	0.002	0.998	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.998	0.002
M41.8 Other forms of scoliosis	0.002	0.998	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.002	0.998	0.000
M60.05 Infective myositis (Pelvic region and thigh)	0.002	0.998	0.000
D84 Other immunodeficiencies	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.000	0.998	0.002
D81.8 Other combined immunodeficiencies	0.000	0.998	0.002
D81.7 Major histocompatibility complex class II deficiency	0.000	0.998	0.002
D81.6 Major histocompatibility complex class I deficiency	0.000	0.998	0.002
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.998	0.002
D81.4 Nezelof's syndrome	0.000	0.998	0.002
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.998	0.002
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.998	0.002
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.998	0.002
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.998	0.002
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.998	0.002
K50.8 Other Crohn's disease	0.000	0.998	0.002
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.998	0.002
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.998	0.002
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.998	0.002
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.998	0.002
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.998	0.002
H53.2 Diplopia	0.000	0.998	0.002
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.998	0.002
D10.1 Tongue	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.998	0.002
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.998	0.002
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.998	0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.998	0.002
D82.2 Immunodeficiency with short-limbed stature	0.000	0.998	0.002
D82.0 Wiskott-Aldrich syndrome	0.000	0.998	0.002
E27.3 Drug-induced adrenocortical insufficiency	0.001	0.998	0.000
K35 Acute appendicitis	0.002	0.998	0.000
D82.1 Di George's syndrome	0.000	0.998	0.002
M87 Osteonecrosis	0.001	0.998	0.001
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
E66.9 Obesity, unspecified	0.002	0.998	0.000
S22.2 Fracture of sternum	0.000	0.998	0.002
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.001	0.998	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.001	0.998	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.001	0.998	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.001	0.998	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.001	0.998	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.001	0.998	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.001	0.998	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.002
M86 Osteomyelitis	0.000	0.998	0.002
D84.1 Defects in the complement system	0.000	0.998	0.001
R43.8 Other and unspecified disturbances of smell and taste	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.000	0.998	0.001
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.998	0.001
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.998	0.001
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.998	0.001
M54.96 Dorsalgia, unspecified (Lumbar region)	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.998	0.002
H18.4 Corneal degeneration	0.002	0.998	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.002	0.998	0.000
A63.8 Other specified predominantly sexually transmitted diseases	0.000	0.998	0.001
M87.9 Osteonecrosis, unspecified	0.001	0.998	0.000
S22.9 Fracture of bony thorax, part unspecified	0.000	0.998	0.001
S22.8 Fracture of other parts of bony thorax	0.000	0.998	0.001
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
H53 Visual disturbances	0.000	0.998	0.002
M86-M90 Other osteopathies	0.000	0.998	0.002
M41.89 Other forms of scoliosis (Site unspecified)	0.001	0.998	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.001	0.998	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.001	0.998	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.001	0.998	0.000
S22.20 Fracture of sternum (closed)	0.000	0.998	0.002
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.998	0.002
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.001	0.998	0.000
E27.2 Addisonian crisis	0.001	0.998	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.001	0.998	0.001
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.001	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.998	0.001
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.998	0.001
H11.0 Pterygium	0.000	0.998	0.002
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
R74.8 Abnormal levels of other serum enzymes	0.000	0.998	0.002
Z03.9 Observation for suspected disease or condition, unspecified	0.000	0.998	0.002
T23.2 Burn of second degree of wrist and hand	0.001	0.998	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.998	0.001
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.998	0.001
M87.3 Other secondary osteonecrosis	0.001	0.998	0.001
M87.1 Osteonecrosis due to drugs	0.001	0.998	0.001
M87.0 Idiopathic aseptic necrosis of bone	0.001	0.998	0.001
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
M60.08 Infective myositis (Other)	0.001	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.998	0.001
S22.21 Fracture of sternum (open)	0.000	0.998	0.001
H53.4 Visual field defects	0.000	0.998	0.002
M87.8 Other osteonecrosis	0.001	0.998	0.000
R46.2 Strange and inexplicable behaviour	0.000	0.998	0.001
M48.00 Spinal stenosis (Multiple sites in spine)	0.001	0.998	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.998	0.001
B18.2 Chronic viral hepatitis C	0.000	0.998	0.001
M86.5 Other chronic haematogenous osteomyelitis	0.000	0.998	0.001
M86.4 Chronic osteomyelitis with draining sinus	0.000	0.998	0.001
M86.3 Chronic multifocal osteomyelitis	0.000	0.998	0.001
M86.2 Subacute osteomyelitis	0.000	0.998	0.001
M86.0 Acute haematogenous osteomyelitis	0.000	0.998	0.001
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.001
M87.96 Osteonecrosis, unspecified (Lower leg)	0.001	0.999	0.000
O03.4 Incomplete, without complication	0.001	0.999	0.000
S22.4 Multiple fractures of ribs	0.000	0.999	0.001
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.999	0.001
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.999	0.001
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.999	0.001
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.999	0.001
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.999	0.001
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.001	0.999	0.000
D07.5 Prostate	0.000	0.999	0.001
M65.14 Other infective (teno)synovitis (Hand)	0.001	0.999	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.001	0.999	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.001	0.999	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.001	0.999	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.001	0.999	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.001	0.999	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.001	0.999	0.000
H53.6 Night blindness	0.000	0.999	0.001
H53.5 Colour vision deficiencies	0.000	0.999	0.001
K35.3 Acute appendicitis with localized peritonitis	0.001	0.999	0.000
M60.0 Infective myositis	0.001	0.999	0.000
S22.5 Flail chest	0.000	0.999	0.001
W18.5 Trade and service area	0.000	0.999	0.001
W84.9 Unspecified place	0.001	0.999	0.000
B18 Chronic viral hepatitis	0.000	0.999	0.001
D83.9 Common variable immunodeficiency, unspecified	0.000	0.999	0.001
M86.8 Other osteomyelitis	0.000	0.999	0.001
T23.0 Burn of unspecified degree of wrist and hand	0.001	0.999	0.000
M90 Osteopathies in diseases classified elsewhere	0.000	0.999	0.001
D84.8 Other specified immunodeficiencies	0.000	0.999	0.001
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.001	0.999	0.000
M86.1 Other acute osteomyelitis	0.000	0.999	0.001
G31.8 Other specified degenerative diseases of nervous system	0.001	0.999	0.000
J38.3 Other diseases of vocal cords	0.001	0.999	0.000
S01.3 Open wound of ear	0.001	0.999	0.000
S51.0 Open wound of elbow	0.001	0.999	0.000
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.001	0.999	0.001
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.001	0.999	0.001
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.001	0.999	0.001
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.001	0.999	0.001
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.001	0.999	0.001
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.001	0.999	0.001
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.001	0.999	0.001
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.001	0.999	0.001
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.001	0.999	0.001
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.001	0.999	0.001
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.001	0.999	0.001
M87.18 Osteonecrosis due to drugs (Other)	0.001	0.999	0.001
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.001	0.999	0.001
M87.16 Osteonecrosis due to drugs (Lower leg)	0.001	0.999	0.001
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.001	0.999	0.001
M87.14 Osteonecrosis due to drugs (Hand)	0.001	0.999	0.001
M87.13 Osteonecrosis due to drugs (Forearm)	0.001	0.999	0.001
M87.12 Osteonecrosis due to drugs (Upper arm)	0.001	0.999	0.001
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.001	0.999	0.001
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.001	0.999	0.001
M87.39 Other secondary osteonecrosis (Site unspecified)	0.001	0.999	0.001
M87.38 Other secondary osteonecrosis (Other)	0.001	0.999	0.001
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.001	0.999	0.001
M87.36 Other secondary osteonecrosis (Lower leg)	0.001	0.999	0.001
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.001	0.999	0.001
M87.34 Other secondary osteonecrosis (Hand)	0.001	0.999	0.001
M87.33 Other secondary osteonecrosis (Forearm)	0.001	0.999	0.001
M87.32 Other secondary osteonecrosis (Upper arm)	0.001	0.999	0.001
M87.31 Other secondary osteonecrosis (Shoulder region)	0.001	0.999	0.001
M87.30 Other secondary osteonecrosis (Multiple sites)	0.001	0.999	0.001
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.001	0.999	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.001	0.999	0.000
M87.88 Other osteonecrosis (Other)	0.001	0.999	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.001	0.999	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.001	0.999	0.000
M87.84 Other osteonecrosis (Hand)	0.001	0.999	0.000
M87.83 Other osteonecrosis (Forearm)	0.001	0.999	0.000
M87.82 Other osteonecrosis (Upper arm)	0.001	0.999	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.001	0.999	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.001	0.999	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.999	0.001
D80 Immunodeficiency with predominantly antibody defects	0.000	0.999	0.001
M86.09 Acute haematogenous osteomyelitis (Site unspecified)	0.000	0.999	0.001
M86.08 Acute haematogenous osteomyelitis (Other)	0.000	0.999	0.001
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)	0.000	0.999	0.001
M86.06 Acute haematogenous osteomyelitis (Lower leg)	0.000	0.999	0.001
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)	0.000	0.999	0.001
M86.04 Acute haematogenous osteomyelitis (Hand)	0.000	0.999	0.001
M86.03 Acute haematogenous osteomyelitis (Forearm)	0.000	0.999	0.001
M86.02 Acute haematogenous osteomyelitis (Upper arm)	0.000	0.999	0.001
M86.01 Acute haematogenous osteomyelitis (Shoulder region)	0.000	0.999	0.001
M86.00 Acute haematogenous osteomyelitis (Multiple sites)	0.000	0.999	0.001
M86.29 Subacute osteomyelitis (Site unspecified)	0.000	0.999	0.001
M86.28 Subacute osteomyelitis (Other)	0.000	0.999	0.001
M86.27 Subacute osteomyelitis (Ankle and foot)	0.000	0.999	0.001
M86.26 Subacute osteomyelitis (Lower leg)	0.000	0.999	0.001
M86.25 Subacute osteomyelitis (Pelvic region and thigh)	0.000	0.999	0.001
M86.24 Subacute osteomyelitis (Hand)	0.000	0.999	0.001
M86.23 Subacute osteomyelitis (Forearm)	0.000	0.999	0.001
M86.22 Subacute osteomyelitis (Upper arm)	0.000	0.999	0.001
M86.21 Subacute osteomyelitis (Shoulder region)	0.000	0.999	0.001
M86.20 Subacute osteomyelitis (Multiple sites)	0.000	0.999	0.001
M86.39 Chronic multifocal osteomyelitis (Site unspecified)	0.000	0.999	0.001
M86.38 Chronic multifocal osteomyelitis (Other)	0.000	0.999	0.001
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)	0.000	0.999	0.001
M86.36 Chronic multifocal osteomyelitis (Lower leg)	0.000	0.999	0.001
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)	0.000	0.999	0.001
M86.34 Chronic multifocal osteomyelitis (Hand)	0.000	0.999	0.001
M86.33 Chronic multifocal osteomyelitis (Forearm)	0.000	0.999	0.001
M86.32 Chronic multifocal osteomyelitis (Upper arm)	0.000	0.999	0.001
M86.31 Chronic multifocal osteomyelitis (Shoulder region)	0.000	0.999	0.001
M86.30 Chronic multifocal osteomyelitis (Multiple sites)	0.000	0.999	0.001
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)	0.000	0.999	0.001
M86.48 Chronic osteomyelitis with draining sinus (Other)	0.000	0.999	0.001
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.000	0.999	0.001
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)	0.000	0.999	0.001
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)	0.000	0.999	0.001
M86.44 Chronic osteomyelitis with draining sinus (Hand)	0.000	0.999	0.001
M86.43 Chronic osteomyelitis with draining sinus (Forearm)	0.000	0.999	0.001
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)	0.000	0.999	0.001
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)	0.000	0.999	0.001
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)	0.000	0.999	0.001
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)	0.000	0.999	0.001
M86.58 Other chronic haematogenous osteomyelitis (Other)	0.000	0.999	0.001
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)	0.000	0.999	0.001
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)	0.000	0.999	0.001
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)	0.000	0.999	0.001
M86.54 Other chronic haematogenous osteomyelitis (Hand)	0.000	0.999	0.001
M86.53 Other chronic haematogenous osteomyelitis (Forearm)	0.000	0.999	0.001
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)	0.000	0.999	0.001
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)	0.000	0.999	0.001
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)	0.000	0.999	0.001
M87.86 Other osteonecrosis (Lower leg)	0.001	0.999	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.999	0.001
G04.1 Tropical spastic paraplegia	0.000	0.999	0.001
G04.0 Acute disseminated encephalitis	0.000	0.999	0.001
G58.8 Other specified mononeuropathies	0.000	0.999	0.001
L03.3 Cellulitis of trunk	0.001	0.999	0.000
M86.6 Other chronic osteomyelitis	0.000	0.999	0.001
S22.1 Multiple fractures of thoracic spine	0.000	0.999	0.001
M86.87 Other osteomyelitis (Ankle and foot)	0.000	0.999	0.001
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.001	0.999	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.999	0.001
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.999	0.001
G03.9 Meningitis, unspecified	0.000	0.999	0.001
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
R25.1 Tremor, unspecified	0.000	0.999	0.001
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.000	0.999	0.001
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.999	0.001
B18.8 Other chronic viral hepatitis	0.000	0.999	0.001
B18.0 Chronic viral hepatitis B with delta-agent	0.000	0.999	0.001
E27.4 Other and unspecified adrenocortical insufficiency	0.001	0.999	0.000
H53.3 Other disorders of binocular vision	0.000	0.999	0.001
K56.1 Intussusception	0.000	0.999	0.001
N87.9 Dysplasia of cervix uteri, unspecified	0.001	0.999	0.000
Q89.2 Congenital malformations of other endocrine glands	0.000	0.999	0.001
W15.8 Other specified place	0.001	0.999	0.000
M89 Other disorders of bone	0.000	0.999	0.001
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.001	0.999	0.000
M60.09 Infective myositis (Site unspecified)	0.001	0.999	0.000
M60.07 Infective myositis (Ankle and foot)	0.001	0.999	0.000
M60.06 Infective myositis (Lower leg)	0.001	0.999	0.000
M60.04 Infective myositis (Hand)	0.001	0.999	0.000
M60.03 Infective myositis (Forearm)	0.001	0.999	0.000
M60.02 Infective myositis (Upper arm)	0.001	0.999	0.000
M60.01 Infective myositis (Shoulder region)	0.001	0.999	0.000
M60.00 Infective myositis (Multiple sites)	0.001	0.999	0.000
M86.89 Other osteomyelitis (Site unspecified)	0.000	0.999	0.001
M86.88 Other osteomyelitis (Other)	0.000	0.999	0.001
M86.84 Other osteomyelitis (Hand)	0.000	0.999	0.001
M86.83 Other osteomyelitis (Forearm)	0.000	0.999	0.001
M86.82 Other osteomyelitis (Upper arm)	0.000	0.999	0.001
M86.81 Other osteomyelitis (Shoulder region)	0.000	0.999	0.001
M86.80 Other osteomyelitis (Multiple sites)	0.000	0.999	0.001
S22.51 Flail chest (open)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations