TreeWAS – Variant ID: rs2577720

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.467	0.533	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.332	0.668	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.286	0.714	0.000
T39.0 Salicylates	0.245	0.755	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.244	0.756	0.000
T39.4 Antirheumatics, not elsewhere classified	0.238	0.762	0.000
T39.2 Pyrazolone derivatives	0.238	0.762	0.000
T39.1 4-Aminophenol derivatives	0.233	0.767	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.121	0.879	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.118	0.882	0.000
T40.2 Other opioids	0.116	0.884	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.116	0.884	0.000
T43.2 Other and unspecified antidepressants	0.111	0.889	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.099	0.901	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.099	0.901	0.000
T40.6 Other and unspecified narcotics	0.094	0.906	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.092	0.907	0.000
R10.1 Pain localised to upper abdomen	0.000	0.910	0.090
T36 Poisoning by systemic antibiotics	0.090	0.910	0.000
T40.3 Methadone	0.089	0.911	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.088	0.912	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.087	0.913	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.084	0.915	0.000
T40.8 Lysergide [LSD]	0.084	0.915	0.000
T40.7 Cannabis (derivatives)	0.084	0.915	0.000
T40.0 Opium	0.084	0.915	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.083	0.917	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.083	0.917	0.000
T40.1 Heroin	0.082	0.918	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.081	0.918	0.000
T43.9 Psychotropic drug, unspecified	0.081	0.919	0.000
T43.6 Psychostimulants with abuse potential	0.081	0.919	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.079	0.920	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.078	0.922	0.000
T40.5 Cocaine	0.077	0.923	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.075	0.925	0.000
T40.4 Other synthetic narcotics	0.074	0.926	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.072	0.928	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.072	0.928	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.069	0.931	0.000
T36.8 Other systemic antibiotics	0.068	0.932	0.000
T36.3 Macrolides	0.067	0.933	0.000
T49.9 Topical agent, unspecified	0.066	0.933	0.000
T49.8 Other topical agents	0.066	0.933	0.000
T49.7 Dental drugs, topically applied	0.066	0.933	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.066	0.933	0.000
T49.5 Ophthalmological drugs and preparations	0.066	0.933	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.066	0.933	0.000
T49.3 Emollients, demulcents and protectants	0.066	0.933	0.000
T49.2 Local astringents and local detergents	0.066	0.933	0.000
T49.1 Antipruritics	0.066	0.933	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.066	0.934	0.000
T48.5 Anti-common-cold drugs	0.066	0.934	0.000
T36.0 Penicillins	0.065	0.935	0.000
T36.9 Systemic antibiotic, unspecified	0.064	0.935	0.000
T36.7 Antifungal antibiotics, systemically used	0.064	0.935	0.000
T36.6 Rifamycins	0.064	0.935	0.000
T36.5 Aminoglycosides	0.064	0.935	0.000
T36.2 Chloramphenicol group	0.064	0.935	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.064	0.935	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.064	0.936	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.063	0.937	0.000
T37.5 Antiviral drugs	0.063	0.937	0.000
T37.4 Anthelminthics	0.063	0.937	0.000
T37.3 Other antiprotozoal drugs	0.063	0.937	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.063	0.937	0.000
T37.1 Antimycobacterial drugs	0.063	0.937	0.000
T37.0 Sulphonamides	0.063	0.937	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.063	0.937	0.000
T41.5 Therapeutic gases	0.062	0.937	0.000
T41.4 Anaesthetic, unspecified	0.062	0.937	0.000
T41.3 Local anaesthetics	0.062	0.937	0.000
T41.2 Other and unspecified general anaesthetics	0.062	0.937	0.000
T41.1 Intravenous anaesthetics	0.062	0.937	0.000
T41.0 Inhaled anaesthetics	0.062	0.937	0.000
T47.2 Stimulant laxatives	0.061	0.939	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.060	0.939	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.060	0.940	0.000
T36.4 Tetracyclines	0.060	0.940	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.060	0.940	0.000
T46.7 Peripheral vasodilators	0.060	0.940	0.000
K83.8 Other specified diseases of biliary tract	0.000	0.941	0.059
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.059	0.941	0.000
T48.4 Expectorants	0.059	0.941	0.000
T48.3 Antitussives	0.059	0.941	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.059	0.941	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.059	0.941	0.000
T48.0 Oxytocic drugs	0.059	0.941	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.058	0.941	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.058	0.942	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.057	0.942	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.057	0.942	0.000
T47.4 Other laxatives	0.056	0.944	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.056	0.944	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.056	0.944	0.000
T47.7 Emetics	0.056	0.944	0.000
T47.5 Digestants	0.056	0.944	0.000
T47.3 Saline and osmotic laxatives	0.056	0.944	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.055	0.944	0.000
T47.6 Antidiarrhoeal drugs	0.054	0.945	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.053	0.947	0.000
T50.7 Analeptics and opioid receptor antagonists	0.052	0.948	0.000
T50.5 Appetite depressants	0.052	0.948	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.052	0.948	0.000
T50.1 Loop [high-ceiling] diuretics	0.052	0.948	0.000
T50.0 Mineralocorticoids and their antagonists	0.052	0.948	0.000
T50.8 Diagnostic agents	0.051	0.949	0.000
T50.4 Drugs affecting uric acid metabolism	0.051	0.949	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.049	0.950	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.047	0.953	0.000
T47.0 Histamine H(2)-receptor antagonists	0.047	0.953	0.000
T38.9 Other and unspecified hormone antagonists	0.043	0.957	0.000
T38.7 Androgens and anabolic congeners	0.043	0.957	0.000
T38.5 Other oestrogens and progestogens	0.043	0.957	0.000
T38.4 Oral contraceptives	0.043	0.957	0.000
T38.2 Antithyroid drugs	0.043	0.957	0.000
T38.0 Glucocorticoids and synthetic analogues	0.043	0.957	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.041	0.958	0.001
T48.6 Antiasthmatics, not elsewhere classified	0.041	0.959	0.001
T46.1 Calcium-channel blockers	0.040	0.960	0.000
T38.1 Thyroid hormones and substitutes	0.038	0.962	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.038	0.962	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.034	0.966	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.029	0.970	0.001
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.029	0.970	0.001
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.029	0.970	0.001
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.029	0.970	0.001
T44.1 Other parasympathomimetics [cholinergics]	0.029	0.970	0.001
T44.0 Anticholinesterase agents	0.029	0.970	0.001
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.028	0.970	0.001
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.028	0.971	0.001
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.028	0.972	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.027	0.972	0.001
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.026	0.973	0.001
K37 Unspecified appendicitis	0.000	0.974	0.026
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.026	0.974	0.000
T45.4 Iron and its compounds	0.023	0.977	0.001
C34.3 Lower lobe, bronchus or lung	0.022	0.978	0.000
K35-K38 Diseases of appendix	0.000	0.978	0.022
T45.9 Primarily systemic and haematological agent, unspecified	0.021	0.979	0.001
T45.8 Other primarily systemic and haematological agents	0.021	0.979	0.001
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.021	0.979	0.001
T45.6 Fibrinolysis-affecting drugs	0.021	0.979	0.001
T45.3 Enzymes, not elsewhere classified	0.021	0.979	0.001
K35 Acute appendicitis	0.000	0.979	0.021
T42.3 Barbiturates	0.021	0.979	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.020	0.980	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.020	0.980	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.981	0.019
K35.9 Acute appendicitis, unspecified	0.000	0.981	0.019
H66.3 Other chronic suppurative otitis media	0.000	0.981	0.019
T42.5 Mixed antiepileptics, not elsewhere classified	0.019	0.981	0.000
T42.2 Succinimides and oxazolidinediones	0.019	0.981	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.017	0.982	0.001
K38 Other diseases of appendix	0.000	0.983	0.017
T45.2 Vitamins, not elsewhere classified	0.016	0.983	0.001
K35.3 Acute appendicitis with localized peritonitis	0.000	0.983	0.017
K35.8 Acute appendicitis, other and unspecified	0.000	0.983	0.017
K36 Other appendicitis	0.000	0.984	0.016
T42.0 Hydantoin derivatives	0.015	0.985	0.000
K38.1 Appendicular concretions	0.000	0.985	0.015
K35.2 Acute appendicitis with generalized peritonitis	0.000	0.986	0.014
T45.5 Anticoagulants	0.013	0.986	0.001
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.987	0.013
K38.2 Diverticulum of appendix	0.000	0.987	0.013
T42.1 Iminostilbenes	0.012	0.987	0.000
K38.3 Fistula of appendix	0.000	0.987	0.013
K38.9 Disease of appendix, unspecified	0.000	0.987	0.013
K85.9 Acute pancreatitis, unspecified	0.000	0.987	0.013
H66 Suppurative and unspecified otitis media	0.000	0.988	0.012
K38.8 Other specified diseases of appendix	0.000	0.988	0.012
H60.9 Otitis externa, unspecified	0.000	0.989	0.011
K38.0 Hyperplasia of appendix	0.000	0.989	0.011
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.989	0.011
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.989	0.011
H60 Otitis externa	0.000	0.989	0.011
T45.0 Antiallergic and antiemetic drugs	0.008	0.990	0.001
H66.0 Acute suppurative otitis media	0.000	0.990	0.010
C34 Malignant neoplasm of bronchus and lung	0.010	0.990	0.000
H60.4 Cholesteatoma of external ear	0.000	0.990	0.010
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.008	0.990	0.002
H60.3 Other infective otitis externa	0.000	0.991	0.009
H66.4 Suppurative otitis media, unspecified	0.000	0.991	0.009
C34.1 Upper lobe, bronchus or lung	0.009	0.991	0.000
H60.0 Abscess of external ear	0.000	0.992	0.008
H61.8 Other specified disorders of external ear	0.000	0.992	0.008
K83 Other diseases of biliary tract	0.000	0.992	0.008
H60.2 Malignant otitis externa	0.000	0.992	0.008
H60-H62 Diseases of external ear	0.000	0.992	0.008
K85 Acute pancreatitis	0.000	0.992	0.008
C34.2 Middle lobe, bronchus or lung	0.007	0.992	0.000
H60.5 Acute otitis externa, non-infective	0.000	0.993	0.007
C34.9 Bronchus or lung, unspecified	0.007	0.993	0.000
K83.3 Fistula of bile duct	0.000	0.993	0.007
H60.1 Cellulitis of external ear	0.000	0.993	0.007
K83.5 Biliary cyst	0.000	0.993	0.007
H61 Other disorders of external ear	0.000	0.993	0.007
K85.8 Other acute pancreatitis	0.000	0.993	0.007
A63.0 Anogenital (venereal) warts	0.000	0.993	0.007
C34.8 Overlapping lesion of bronchus and lung	0.007	0.993	0.000
H69.8 Other specified disorders of Eustachian tube	0.000	0.993	0.007
H69 Other disorders of Eustachian tube	0.000	0.994	0.006
T42.4 Benzodiazepines	0.006	0.994	0.000
H60.8 Other otitis externa	0.000	0.994	0.006
K85.3 Drug-induced acute pancreatitis	0.000	0.994	0.006
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.994	0.006
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.994	0.006
H61.9 Disorder of external ear, unspecified	0.000	0.994	0.006
H65-H75 Diseases of middle ear and mastoid	0.000	0.994	0.006
K83.4 Spasm of sphincter of Oddi	0.000	0.994	0.006
S91.3 Open wound of other parts of foot	0.006	0.994	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.994	0.006
K83.2 Perforation of bile duct	0.000	0.994	0.005
D34 Benign neoplasm of thyroid gland	0.000	0.995	0.005
H54.7 Unspecified visual loss	0.000	0.995	0.005
K85.1 Biliary acute pancreatitis	0.000	0.995	0.005
H10.9 Conjunctivitis, unspecified	0.000	0.995	0.005
K85.2 Alcohol-induced acute pancreatitis	0.000	0.995	0.005
K85.0 Idiopathic acute pancreatitis	0.000	0.995	0.005
H61.2 Impacted cerumen	0.000	0.995	0.005
H71 Cholesteatoma of middle ear	0.000	0.995	0.005
C45.0 Mesothelioma of pleura	0.005	0.995	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.005	0.995	0.000
H69.0 Patulous Eustachian tube	0.000	0.995	0.005
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.995	0.005
S79.9 Unspecified injury of hip and thigh	0.000	0.995	0.005
H61.3 Acquired stenosis of external ear canal	0.000	0.995	0.005
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.995	0.004
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.995	0.004
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.995	0.004
H62.2 Otitis externa in mycoses	0.000	0.995	0.004
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.995	0.004
H68 Eustachian salpingitis and obstruction	0.000	0.995	0.004
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.004	0.995	0.000
S91 Open wound of ankle and foot	0.004	0.995	0.000
K86.8 Other specified diseases of pancreas	0.000	0.996	0.004
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.996	0.004
H67 Otitis media in diseases classified elsewhere	0.000	0.996	0.004
K83.0 Cholangitis	0.000	0.996	0.004
K83.9 Disease of biliary tract, unspecified	0.000	0.996	0.004
S96 Injury of muscle and tendon at ankle and foot level	0.004	0.996	0.000
C45.7 Mesothelioma of other sites	0.004	0.996	0.000
C45 Mesothelioma	0.004	0.996	0.000
D48.1 Connective and other soft tissue	0.000	0.996	0.004
Chapter VIII Diseases of the ear and mastoid process	0.000	0.996	0.004
S96.8 Injury of other muscles and tendons at ankle and foot level	0.004	0.996	0.000
H61.1 Non-infective disorders of pinna	0.000	0.996	0.004
C45.9 Mesothelioma, unspecified	0.004	0.996	0.000
L29.2 Pruritus vulvae	0.000	0.996	0.004
D48.5 Skin	0.000	0.996	0.004
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.996	0.004
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.004	0.996	0.000
S91.2 Open wound of toe(s) with damage to nail	0.004	0.996	0.000
H68.1 Obstruction of Eustachian tube	0.000	0.996	0.004
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.000	0.996	0.004
C34.0 Main bronchus	0.003	0.996	0.000
H68.0 Eustachian salpingitis	0.000	0.996	0.003
K09.0 Developmental odontogenic cysts	0.004	0.996	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.996	0.003
S90-S99 Injuries to the ankle and foot	0.004	0.996	0.000
S91.7 Multiple open wounds of ankle and foot	0.003	0.996	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.997	0.003
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.997	0.003
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.997	0.003
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.997	0.003
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.003	0.997	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.003	0.997	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.003	0.997	0.000
T79.6 Traumatic ischaemia of muscle	0.003	0.997	0.000
F99 Mental disorder, not otherwise specified	0.000	0.997	0.003
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.997	0.003
H10 Conjunctivitis	0.000	0.997	0.003
H72 Perforation of tympanic membrane	0.000	0.997	0.003
S91.1 Open wound of toe(s) without damage to nail	0.003	0.997	0.000
C45.2 Mesothelioma of pericardium	0.003	0.997	0.000
C45.1 Mesothelioma of peritoneum	0.003	0.997	0.000
G47.9 Sleep disorder, unspecified	0.003	0.997	0.000
H73 Other disorders of tympanic membrane	0.000	0.997	0.003
H72.0 Central perforation of tympanic membrane	0.000	0.997	0.003
S91.0 Open wound of ankle	0.003	0.997	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.997	0.003
S97 Crushing injury of ankle and foot	0.003	0.997	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.000	0.997	0.003
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.997	0.003
H70 Mastoiditis and related conditions	0.000	0.997	0.003
B00.4 Herpesviral encephalitis	0.000	0.997	0.003
H10.4 Chronic conjunctivitis	0.000	0.997	0.003
H66.9 Otitis media, unspecified	0.000	0.997	0.003
K86 Other diseases of pancreas	0.000	0.997	0.003
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.003	0.997	0.000
S82.20 Fracture of shaft of tibia (closed)	0.003	0.997	0.000
H18.8 Other specified disorders of cornea	0.000	0.997	0.003
H74 Other disorders of middle ear and mastoid	0.000	0.997	0.003
S90.8 Other superficial injuries of ankle and foot	0.003	0.997	0.000
H72.1 Attic perforation of tympanic membrane	0.000	0.997	0.003
B00.9 Herpesviral infection, unspecified	0.000	0.997	0.003
D48.0 Bone and articular cartilage	0.000	0.997	0.003
S97.8 Crushing injury of other parts of ankle and foot	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.003	0.997	0.000
S90 Superficial injury of ankle and foot	0.003	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.003	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.003	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.003	0.997	0.000
H74.4 Polyp of middle ear	0.000	0.997	0.003
C38.4 Pleura	0.003	0.997	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.003	0.997	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.997	0.003
A63.8 Other specified predominantly sexually transmitted diseases	0.000	0.997	0.003
H10.8 Other conjunctivitis	0.000	0.997	0.003
H10.5 Blepharoconjunctivitis	0.000	0.997	0.003
H10.3 Acute conjunctivitis, unspecified	0.000	0.997	0.003
H10.2 Other acute conjunctivitis	0.000	0.997	0.003
H10.1 Acute atopic conjunctivitis	0.000	0.997	0.003
H10.0 Mucopurulent conjunctivitis	0.000	0.997	0.003
H72.2 Other marginal perforations of tympanic membrane	0.000	0.997	0.003
C33 Malignant neoplasm of trachea	0.003	0.997	0.000
K86.2 Cyst of pancreas	0.000	0.997	0.003
W29.9 Unspecified place	0.003	0.997	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.997	0.003
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.000	0.997	0.003
S99.8 Other specified injuries of ankle and foot	0.003	0.997	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.997	0.002
D48.3 Retroperitoneum	0.000	0.997	0.002
F34.1 Dysthymia	0.000	0.997	0.003
S97.1 Crushing injury of toe(s)	0.002	0.997	0.000
C31 Malignant neoplasm of accessory sinuses	0.002	0.997	0.000
S97.0 Crushing injury of ankle	0.002	0.997	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.002	0.998	0.000
B00 Herpesviral [herpes simplex] infections	0.000	0.998	0.002
S52.60 Fracture of lower end of both ulna and radius (closed)	0.002	0.998	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.998	0.002
H70.2 Petrositis	0.000	0.998	0.002
H70.0 Acute mastoiditis	0.000	0.998	0.002
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
H11.0 Pterygium	0.000	0.998	0.002
E07.9 Disorder of thyroid, unspecified	0.002	0.998	0.000
H73.1 Chronic myringitis	0.000	0.998	0.002
H73.0 Acute myringitis	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.002	0.998	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.002	0.998	0.000
D48.4 Peritoneum	0.000	0.998	0.002
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.000	0.998	0.002
Z31.2 In vitro fertilisation	0.002	0.998	0.000
N99.1 Postprocedural urethral stricture	0.000	0.998	0.002
S90.0 Contusion of ankle	0.002	0.998	0.000
H70.9 Mastoiditis, unspecified	0.000	0.998	0.002
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.998	0.000
S98.1 Traumatic amputation of one toe	0.002	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.998	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.002	0.998	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.998	0.002
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.998	0.002
T79 Certain early complications of trauma, not elsewhere classified	0.002	0.998	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.002	0.998	0.000
C38.2 Posterior mediastinum	0.002	0.998	0.000
C38.1 Anterior mediastinum	0.002	0.998	0.000
C38.0 Heart	0.002	0.998	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.998	0.002
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.998	0.002
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.998	0.002
S02.20 Fracture of nasal bones (closed)	0.002	0.998	0.000
C31.0 Maxillary sinus	0.002	0.998	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.998	0.002
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.002
N05.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
O80.9 Single spontaneous delivery, unspecified	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.998	0.002
K51.9 Ulcerative colitis, unspecified	0.000	0.998	0.002
N05.9 Unspecified	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
B00.1 Herpesviral vesicular dermatitis	0.000	0.998	0.002
C37 Malignant neoplasm of thymus	0.002	0.998	0.000
S79 Other and unspecified injuries of hip and thigh	0.000	0.998	0.002
H70.8 Other mastoiditis and related conditions	0.001	0.998	0.002
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.998	0.002
C30 Malignant neoplasm of nasal cavity and middle ear	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.998	0.002
C31.9 Accessory sinus, unspecified	0.002	0.998	0.000
C31.8 Overlapping lesion of accessory sinuses	0.002	0.998	0.000
C31.3 Sphenoidal sinus	0.002	0.998	0.000
C31.2 Frontal sinus	0.002	0.998	0.000
C31.1 Ethmoidal sinus	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
D48.6 Breast	0.000	0.998	0.002
N05 Unspecified nephritic syndrome	0.002	0.998	0.000
B00.7 Disseminated herpesviral disease	0.000	0.998	0.002
B00.3 Herpesviral meningitis	0.000	0.998	0.002
B00.0 Eczema herpeticum	0.000	0.998	0.002
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
T79.4 Traumatic shock	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
C39.9 Ill-defined sites within the respiratory system	0.002	0.998	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.002	0.998	0.000
C39.0 Upper respiratory tract, part unspecified	0.002	0.998	0.000
H70.1 Chronic mastoiditis	0.001	0.998	0.001
C38.3 Mediastinum, part unspecified	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.998	0.002
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
A87.9 Viral meningitis, unspecified	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
L81.9 Disorder of pigmentation, unspecified	0.000	0.998	0.002
G44.0 Cluster headache syndrome	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.998	0.002
Z31 Procreative management	0.002	0.998	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.998	0.002
H65.2 Chronic serous otitis media	0.000	0.998	0.002
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.002	0.998	0.000
T79.9 Unspecified early complication of trauma	0.002	0.998	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.002	0.998	0.000
T79.1 Fat embolism (traumatic)	0.002	0.998	0.000
T79.0 Air embolism (traumatic)	0.002	0.998	0.000
X62.9 Unspecified place	0.002	0.998	0.000
D48.7 Other specified sites	0.000	0.998	0.002
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.998	0.002
X63.0 Home	0.000	0.998	0.002
I81 Portal vein thrombosis	0.000	0.998	0.002
H74.1 Adhesive middle ear disease	0.000	0.998	0.002
I46.0 Cardiac arrest with successful resuscitation	0.000	0.998	0.002
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.000	0.998	0.002
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.000	0.998	0.002
C30.1 Middle ear	0.002	0.998	0.000
S79.7 Multiple injuries of hip and thigh	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.002	0.998	0.000
B00.5 Herpesviral ocular disease	0.000	0.998	0.002
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
T79.7 Traumatic subcutaneous emphysema	0.002	0.998	0.000
S62.61 Fracture of other finger (open)	0.002	0.998	0.000
B00.8 Other forms of herpesviral infection	0.000	0.998	0.002
H54.5 Low vision, one eye	0.000	0.998	0.002
H74.0 Tympanosclerosis	0.000	0.998	0.002
H54 Blindness and low vision	0.000	0.998	0.002
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.998	0.002
N05.6 Dense deposit disease	0.002	0.998	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N05.0 Minor glomerular abnormality	0.002	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
T79.5 Traumatic anuria	0.002	0.998	0.000
Z31.8 Other procreative management	0.002	0.998	0.000
H65 Nonsuppurative otitis media	0.000	0.998	0.002
S93.40 Sprain of unspecified ligament of ankle	0.001	0.998	0.000
C92.1 Chronic myeloid leukaemia	0.000	0.998	0.002
Z31.3 Other assisted fertilisation methods	0.002	0.998	0.000
Z48.9 Surgical follow-up care, unspecified	0.002	0.998	0.000
H61.0 Perichondritis of external ear	0.000	0.998	0.002
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.002	0.998	0.000
S79.8 Other specified injuries of hip and thigh	0.000	0.998	0.002
Z90.2 Acquired absence of lung [part of]	0.002	0.998	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.002	0.998	0.000
N05.8 Other	0.002	0.998	0.000
Z31.6 General counselling and advice on procreation	0.002	0.998	0.000
Z31.5 Genetic counselling	0.002	0.998	0.000
Z31.1 Artifical insemination	0.002	0.998	0.000
N02.9 Unspecified	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.001	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.998	0.000
N05.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.001	0.998	0.000
D68.9 Coagulation defect, unspecified	0.000	0.998	0.002
H54.6 Unqualified visual loss, one eye	0.000	0.998	0.001
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T25.2 Burn of second degree of ankle and foot	0.000	0.998	0.001
Z31.4 Procreative investigation and testing	0.002	0.998	0.000
R17 Unspecified jaundice	0.000	0.998	0.002
H54.3 Unqualified visual loss, both eyes	0.000	0.998	0.001
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.001
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations