TreeWAS – Variant ID: rs2581794

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M10.99 Gout, unspecified (Site unspecified)	0.214	0.786	0.000
M10.9 Gout, unspecified	0.205	0.795	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.186	0.814	0.000
M10.90 Gout, unspecified (Multiple sites)	0.183	0.817	0.000
C18 Malignant neoplasm of colon	0.000	0.826	0.174
C15-C26 Malignant neoplasms of digestive organs	0.000	0.827	0.173
M10.96 Gout, unspecified (Lower leg)	0.172	0.828	0.000
C18.2 Ascending colon	0.000	0.830	0.170
M10.93 Gout, unspecified (Forearm)	0.167	0.833	0.000
C20 Malignant neoplasm of rectum	0.000	0.835	0.165
C25 Malignant neoplasm of pancreas	0.000	0.836	0.164
C18.4 Transverse colon	0.000	0.842	0.158
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.844	0.156
M10.98 Gout, unspecified (Other)	0.147	0.853	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.147	0.853	0.000
M10.91 Gout, unspecified (Shoulder region)	0.147	0.853	0.000
C25.0 Head of pancreas	0.000	0.854	0.146
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.854	0.146
C25.9 Pancreas, unspecified	0.000	0.854	0.146
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.855	0.145
C18.0 Caecum	0.000	0.855	0.145
M10.94 Gout, unspecified (Hand)	0.142	0.858	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.858	0.142
C18.1 Appendix	0.000	0.858	0.141
C23 Malignant neoplasm of gallbladder	0.000	0.864	0.136
C22.1 Intrahepatic bile duct carcinoma	0.000	0.865	0.135
C18.9 Colon, unspecified	0.000	0.866	0.134
C25.3 Pancreatic duct	0.000	0.866	0.134
C18.6 Descending colon	0.000	0.871	0.129
C18.8 Overlapping lesion of colon	0.000	0.872	0.128
M10.92 Gout, unspecified (Upper arm)	0.125	0.874	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.879	0.121
C25.8 Overlapping lesion of pancreas	0.000	0.879	0.121
C25.7 Other parts of pancreas	0.000	0.879	0.121
C15.4 Middle third of oesophagus	0.000	0.879	0.121
C24.9 Biliary tract, unspecified	0.000	0.882	0.118
C18.5 Splenic flexure	0.000	0.882	0.118
C18.7 Sigmoid colon	0.000	0.885	0.115
M10 Gout	0.113	0.885	0.002
C24.0 Extrahepatic bile duct	0.000	0.886	0.114
C25.4 Endocrine pancreas	0.000	0.887	0.113
C15.3 Upper third of oesophagus	0.000	0.889	0.111
C25.1 Body of pancreas	0.000	0.890	0.110
C24.1 Ampulla of Vater	0.000	0.894	0.106
C22.7 Other specified carcinomas of liver	0.000	0.895	0.105
C22.4 Other sarcomas of liver	0.000	0.895	0.105
C22.3 Angiosarcoma of liver	0.000	0.895	0.105
C22.2 Hepatoblastoma	0.000	0.895	0.105
C24.8 Overlapping lesion of biliary tract	0.000	0.896	0.104
C25.2 Tail of pancreas	0.000	0.897	0.103
C22.9 Liver, unspecified	0.000	0.897	0.103
C15.9 Oesophagus, unspecified	0.000	0.898	0.102
C15.8 Overlapping lesion of oesophagus	0.000	0.898	0.102
C15.2 Abdominal part of oesophagus	0.000	0.898	0.102
C15.1 Thoracic part of oesophagus	0.000	0.898	0.102
C16 Malignant neoplasm of stomach	0.000	0.901	0.099
C26.0 Intestinal tract, part unspecified	0.000	0.904	0.096
C15.5 Lower third of oesophagus	0.000	0.904	0.096
M10.0 Idiopathic gout	0.092	0.907	0.001
C15.0 Cervical part of oesophagus	0.000	0.908	0.092
C21 Malignant neoplasm of anus and anal canal	0.000	0.910	0.089
C26.8 Overlapping lesion of digestive system	0.000	0.913	0.087
C26.1 Spleen	0.000	0.913	0.087
C22.0 Liver cell carcinoma	0.000	0.917	0.083
M10.3 Gout due to impairment of renal function	0.081	0.917	0.002
M10.4 Other secondary gout	0.081	0.917	0.002
M10.2 Drug-induced gout	0.081	0.917	0.002
M10.1 Lead-induced gout	0.081	0.917	0.002
C16.6 Greater curvature of stomach, unspecified	0.000	0.919	0.081
C16.1 Fundus of stomach	0.000	0.922	0.078
C16.0 Cardia	0.000	0.924	0.076
M10.09 Idiopathic gout (Site unspecified)	0.074	0.925	0.001
C16.2 Body of stomach	0.000	0.928	0.072
C16.5 Lesser curvature of stomach, unspecified	0.000	0.928	0.071
M10.00 Idiopathic gout (Multiple sites)	0.070	0.929	0.001
C26.9 Ill-defined sites within the digestive system	0.000	0.930	0.070
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.930	0.070
M10.07 Idiopathic gout (Ankle and foot)	0.067	0.932	0.001
I84.6 Residual haemorrhoidal skin tags	0.068	0.932	0.000
M10.04 Idiopathic gout (Hand)	0.067	0.932	0.001
C16.3 Pyloric antrum	0.000	0.932	0.068
C18.3 Hepatic flexure	0.000	0.933	0.067
M10.08 Idiopathic gout (Other)	0.066	0.933	0.001
M10.06 Idiopathic gout (Lower leg)	0.066	0.933	0.001
M10.05 Idiopathic gout (Pelvic region and thigh)	0.066	0.933	0.001
M10.03 Idiopathic gout (Forearm)	0.066	0.933	0.001
M10.02 Idiopathic gout (Upper arm)	0.066	0.933	0.001
M10.01 Idiopathic gout (Shoulder region)	0.066	0.933	0.001
C16.4 Pylorus	0.000	0.934	0.065
C21.2 Cloacogenic zone	0.000	0.935	0.064
C16.8 Overlapping lesion of stomach	0.000	0.939	0.061
M10.39 Gout due to impairment of renal function (Site unspecified)	0.058	0.940	0.001
M10.38 Gout due to impairment of renal function (Other)	0.058	0.940	0.001
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.058	0.940	0.001
M10.36 Gout due to impairment of renal function (Lower leg)	0.058	0.940	0.001
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.058	0.940	0.001
M10.34 Gout due to impairment of renal function (Hand)	0.058	0.940	0.001
M10.33 Gout due to impairment of renal function (Forearm)	0.058	0.940	0.001
M10.32 Gout due to impairment of renal function (Upper arm)	0.058	0.940	0.001
M10.31 Gout due to impairment of renal function (Shoulder region)	0.058	0.940	0.001
M10.30 Gout due to impairment of renal function (Multiple sites)	0.058	0.940	0.001
M10.19 Lead-induced gout (Site unspecified)	0.058	0.940	0.001
M10.18 Lead-induced gout (Other)	0.058	0.940	0.001
M10.17 Lead-induced gout (Ankle and foot)	0.058	0.940	0.001
M10.16 Lead-induced gout (Lower leg)	0.058	0.940	0.001
M10.15 Lead-induced gout (Pelvic region and thigh)	0.058	0.940	0.001
M10.14 Lead-induced gout (Hand)	0.058	0.940	0.001
M10.13 Lead-induced gout (Forearm)	0.058	0.940	0.001
M10.12 Lead-induced gout (Upper arm)	0.058	0.940	0.001
M10.11 Lead-induced gout (Shoulder region)	0.058	0.940	0.001
M10.10 Lead-induced gout (Multiple sites)	0.058	0.940	0.001
M10.29 Drug-induced gout (Site unspecified)	0.058	0.940	0.001
M10.28 Drug-induced gout (Other)	0.058	0.940	0.001
M10.27 Drug-induced gout (Ankle and foot)	0.058	0.940	0.001
M10.26 Drug-induced gout (Lower leg)	0.058	0.940	0.001
M10.25 Drug-induced gout (Pelvic region and thigh)	0.058	0.940	0.001
M10.24 Drug-induced gout (Hand)	0.058	0.940	0.001
M10.23 Drug-induced gout (Forearm)	0.058	0.940	0.001
M10.22 Drug-induced gout (Upper arm)	0.058	0.940	0.001
M10.21 Drug-induced gout (Shoulder region)	0.058	0.940	0.001
M10.20 Drug-induced gout (Multiple sites)	0.058	0.940	0.001
M10.49 Other secondary gout (Site unspecified)	0.058	0.940	0.001
M10.48 Other secondary gout (Other)	0.058	0.940	0.001
M10.47 Other secondary gout (Ankle and foot)	0.058	0.940	0.001
M10.46 Other secondary gout (Lower leg)	0.058	0.940	0.001
M10.45 Other secondary gout (Pelvic region and thigh)	0.058	0.940	0.001
M10.44 Other secondary gout (Hand)	0.058	0.940	0.001
M10.43 Other secondary gout (Forearm)	0.058	0.940	0.001
M10.42 Other secondary gout (Upper arm)	0.058	0.940	0.001
M10.41 Other secondary gout (Shoulder region)	0.058	0.940	0.001
M10.40 Other secondary gout (Multiple sites)	0.058	0.940	0.001
C21.0 Anus, unspecified	0.000	0.950	0.050
C17 Malignant neoplasm of small intestine	0.001	0.959	0.040
C21.1 Anal canal	0.000	0.959	0.040
Z45.0 Adjustment and management of cardiac pacemaker	0.037	0.963	0.000
I84 Haemorrhoids	0.036	0.964	0.000
I84.4 External haemorrhoids with other complications	0.035	0.965	0.000
I84.5 External haemorrhoids without complication	0.035	0.965	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.968	0.032
I84.9 Unspecified haemorrhoids without complication	0.031	0.969	0.000
C17.8 Overlapping lesion of small intestine	0.001	0.970	0.029
C17.3 Meckel's diverticulum	0.001	0.970	0.029
C16.9 Stomach, unspecified	0.000	0.970	0.029
C17.2 Ileum	0.001	0.974	0.026
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.974	0.026
C17.1 Jejunum	0.001	0.977	0.021
Q28 Other congenital malformations of circulatory system	0.022	0.978	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.021	0.979	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.021	0.979	0.000
Q27 Other congenital malformations of peripheral vascular system	0.021	0.979	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.021	0.979	0.000
C17.0 Duodenum	0.001	0.979	0.020
I84.1 Internal haemorrhoids with other complications	0.021	0.979	0.000
Q51.3 Bicornate uterus	0.021	0.979	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.979	0.021
Q51 Congenital malformations of uterus and cervix	0.020	0.980	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.980	0.020
I84.3 External thrombosed haemorrhoids	0.019	0.980	0.000
I84.0 Internal thrombosed haemorrhoids	0.019	0.981	0.000
Q27.3 Peripheral arteriovenous malformation	0.019	0.981	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.019	0.981	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.019	0.981	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.981	0.019
Q50-Q56 Congenital malformations of genital organs	0.019	0.981	0.000
Q25 Congenital malformations of great arteries	0.018	0.982	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.982	0.018
Q28.3 Other malformations of cerebral vessels	0.018	0.982	0.000
M05-M14 Inflammatory polyarthropathies	0.010	0.983	0.008
Q27.8 Other specified congenital malformations of peripheral vascular system	0.017	0.983	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.017	0.983	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.017	0.983	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.983	0.017
Q28.0 Arteriovenous malformation of precerebral vessels	0.016	0.984	0.000
M05 Seropositive rheumatoid arthritis	0.004	0.984	0.012
C17.9 Small intestine, unspecified	0.001	0.984	0.015
Q24 Other congenital malformations of heart	0.016	0.984	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.016	0.984	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.984	0.016
Q28.9 Congenital malformation of circulatory system, unspecified	0.016	0.984	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.016	0.984	0.000
Q28.1 Other malformations of precerebral vessels	0.016	0.984	0.000
Z45.8 Adjustment and management of other implanted devices	0.016	0.984	0.000
I84.2 Internal haemorrhoids without complication	0.016	0.984	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.984	0.015
Q25.1 Coarctation of aorta	0.015	0.984	0.000
Q43 Other congenital malformations of intestine	0.015	0.984	0.000
Q26 Congenital malformations of great veins	0.015	0.985	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.015	0.985	0.000
Q27.4 Congenital phlebectasia	0.015	0.985	0.000
Q27.2 Other congenital malformations of renal artery	0.015	0.985	0.000
Q27.1 Congenital renal artery stenosis	0.015	0.985	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.015	0.985	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.985	0.015
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.015	0.985	0.000
Q51.4 Unicornate uterus	0.015	0.985	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.015	0.985	0.000
M06 Other rheumatoid arthritis	0.004	0.985	0.011
Q39 Congenital malformations of oesophagus	0.015	0.985	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.985	0.015
Q25.0 Patent ductus arteriosus	0.015	0.985	0.000
Q53 Undescended testicle	0.015	0.985	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.015	0.985	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.015	0.985	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.015	0.985	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.015	0.985	0.000
Q51.6 Embryonic cyst of cervix	0.015	0.985	0.000
Q51.5 Agenesis and aplasia of cervix	0.015	0.985	0.000
Q51.0 Agenesis and aplasia of uterus	0.015	0.985	0.000
Q35-Q37 Cleft lip and cleft palate	0.014	0.986	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.986	0.014
J92.9 Pleural plaque without asbestos	0.014	0.986	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.986	0.014
Q51.2 Other doubling of uterus	0.014	0.986	0.000
Q55 Other congenital malformations of male genital organs	0.014	0.986	0.000
Q52 Other congenital malformations of female genitalia	0.014	0.986	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.014	0.986	0.000
Q39.6 Diverticulum of oesophagus	0.014	0.986	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.014	0.986	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.986	0.013
Z45 Adjustment and management of implanted device	0.014	0.986	0.000
Q80-Q89 Other congenital malformations	0.014	0.986	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.986	0.013
Q25.9 Congenital malformation of great arteries, unspecified	0.013	0.986	0.000
Q25.8 Other congenital malformations of great arteries	0.013	0.986	0.000
Q25.6 Stenosis of pulmonary artery	0.013	0.986	0.000
Q25.5 Atresia of pulmonary artery	0.013	0.986	0.000
Q25.2 Atresia of aorta	0.013	0.986	0.000
Q40 Other congenital malformations of upper alimentary tract	0.013	0.987	0.000
Q60-Q64 Congenital malformations of the urinary system	0.013	0.987	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.987	0.013
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.987	0.013
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.987	0.013
Q43.3 Congenital malformations of intestinal fixation	0.013	0.987	0.000
Q43.0 Meckel's diverticulum	0.013	0.987	0.000
Q00-Q07 Congenital malformations of the nervous system	0.013	0.987	0.000
Q45 Other congenital malformations of digestive system	0.013	0.987	0.000
Q12 Congenital lens malformations	0.013	0.987	0.000
Q24.0 Dextrocardia	0.013	0.987	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.987	0.012
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.987	0.013
Q25.3 Stenosis of aorta	0.013	0.987	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.007	0.987	0.006
Q24.9 Congenital malformation of the heart, unspecified	0.013	0.987	0.000
M14 Arthropathies in other diseases classified elsewhere	0.009	0.987	0.004
M08 Juvenile arthritis	0.007	0.987	0.006
Q43.1 Hirschsprung's disease	0.013	0.987	0.000
M12 Other specific arthropathies	0.008	0.987	0.005
Q42 Congenital absence, atresia and stenosis of large intestine	0.012	0.987	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.012	0.987	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.987	0.012
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.012	0.988	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.988	0.012
Q53.2 Undescended testicle, bilateral	0.012	0.988	0.000
M05.8 Other seropositive rheumatoid arthritis	0.003	0.988	0.010
Q24.5 Malformation of coronary vessels	0.012	0.988	0.000
Q24.6 Congenital heart block	0.012	0.988	0.000
Q25.4 Other congenital malformations of aorta	0.012	0.988	0.000
Q89 Other congenital malformations, not elsewhere classified	0.012	0.988	0.000
Q22.5 Ebstein's anomaly	0.012	0.988	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.003	0.988	0.009
M05.1 Rheumatoid lung disease	0.003	0.988	0.009
M05.0 Felty's syndrome	0.003	0.988	0.009
Q24.4 Congenital subaortic stenosis	0.012	0.988	0.000
Q24.3 Pulmonary infundibular stenosis	0.012	0.988	0.000
Q24.2 Cor triatriatum	0.012	0.988	0.000
Q24.1 Levocardia	0.012	0.988	0.000
Q12.0 Congenital cataract	0.012	0.988	0.000
O63.1 Prolonged second stage (of labour)	0.000	0.988	0.012
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.988	0.012
M11 Other crystal arthropathies	0.005	0.988	0.007
Q15 Other congenital malformations of eye	0.011	0.988	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.011	0.988	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.011	0.988	0.000
Q22.6 Hypoplastic right heart syndrome	0.011	0.988	0.000
Q22.4 Congenital tricuspid stenosis	0.011	0.988	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.011	0.988	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.011	0.988	0.000
Q22.1 Congenital pulmonary valve stenosis	0.011	0.988	0.000
Q22.0 Pulmonary valve atresia	0.011	0.988	0.000
Q54 Hypospadias	0.012	0.988	0.000
Q61 Cystic kidney disease	0.012	0.988	0.000
M06.3 Rheumatoid nodule	0.002	0.988	0.009
M05.2 Rheumatoid vasculitis	0.003	0.989	0.009
M06.4 Inflammatory polyarthropathy	0.002	0.989	0.009
Q43.7 Persistent cloaca	0.011	0.989	0.000
Q43.6 Congenital fistula of rectum and anus	0.011	0.989	0.000
Q43.5 Ectopic anus	0.011	0.989	0.000
Q43.4 Duplication of intestine	0.011	0.989	0.000
Q43.2 Other congenital functional disorders of colon	0.011	0.989	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.011	0.989	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.011	0.989	0.000
Q20.6 Isomerism of atrial appendages	0.011	0.989	0.000
Q20.5 Discordant atrioventricular connexion	0.011	0.989	0.000
Q20.4 Double inlet ventricle	0.011	0.989	0.000
Q20.3 Discordant ventriculoarterial connexion	0.011	0.989	0.000
Q20.2 Double outlet left ventricle	0.011	0.989	0.000
Q20.1 Double outlet right ventricle	0.011	0.989	0.000
Q20.0 Common arterial trunk	0.011	0.989	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.011	0.989	0.000
Q26.8 Other congenital malformations of great veins	0.011	0.989	0.000
Q26.6 Portal vein-hepatic artery fistula	0.011	0.989	0.000
Q26.5 Anomalous portal venous connexion	0.011	0.989	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.011	0.989	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.011	0.989	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.011	0.989	0.000
Q26.1 Persistent left superior vena cava	0.011	0.989	0.000
Q26.0 Congenital stenosis of vena cava	0.011	0.989	0.000
Q43.8 Other specified congenital malformations of intestine	0.011	0.989	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.011	0.989	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.011	0.989	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.011	0.989	0.000
Q61.2 Polycystic kidney, adult type	0.011	0.989	0.000
M06.2 Rheumatoid bursitis	0.003	0.989	0.008
Q39.9 Congenital malformation of oesophagus, unspecified	0.011	0.989	0.000
Q39.8 Other congenital malformations of oesophagus	0.011	0.989	0.000
Q39.5 Congenital dilatation of oesophagus	0.011	0.989	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.011	0.989	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.011	0.989	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.011	0.989	0.000
Q39.0 Atresia of oesophagus without fistula	0.011	0.989	0.000
Q37 Cleft palate with cleft lip	0.011	0.989	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.011	0.989	0.000
Q39.4 Oesophageal web	0.011	0.989	0.000
Q35 Cleft palate	0.011	0.989	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.011	0.989	0.000
Q96 Turner's syndrome	0.011	0.989	0.000
Q53.9 Undescended testicle, unspecified	0.011	0.989	0.000
Q53.0 Ectopic testis	0.011	0.989	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.011	0.989	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.011	0.989	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.011	0.989	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.011	0.989	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.011	0.989	0.000
Q52.5 Fusion of labia	0.011	0.989	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.011	0.989	0.000
Q14 Congenital malformations of posterior segment of eye	0.011	0.989	0.000
Q13 Congenital malformations of anterior segment of eye	0.011	0.989	0.000
M06.8 Other specified rheumatoid arthritis	0.003	0.989	0.008
Q82 Other congenital malformations of skin	0.011	0.989	0.000
O63.0 Prolonged first stage (of labour)	0.000	0.989	0.011
Q55.6 Other congenital malformations of penis	0.011	0.989	0.000
Q89.2 Congenital malformations of other endocrine glands	0.011	0.989	0.000
Q36 Cleft lip	0.010	0.989	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.989	0.011
Q98.4 Klinefelter's syndrome, unspecified	0.010	0.989	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.010	0.989	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.010	0.989	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.010	0.990	0.000
Q53.1 Undescended testicle, unilateral	0.010	0.990	0.000
M06.1 Adult-onset Still's disease	0.003	0.990	0.007
Q07 Other congenital malformations of nervous system	0.010	0.990	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.990	0.010
Q55.9 Congenital malformation of male genital organ, unspecified	0.010	0.990	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.010	0.990	0.000
Q55.5 Congenital absence and aplasia of penis	0.010	0.990	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.010	0.990	0.000
Q55.3 Atresia of vas deferens	0.010	0.990	0.000
Q55.1 Hypoplasia of testis and scrotum	0.010	0.990	0.000
Q55.0 Absence and aplasia of testis	0.010	0.990	0.000
Q45.8 Other specified congenital malformations of digestive system	0.010	0.990	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.010	0.990	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.010	0.990	0.000
Q52.7 Other congenital malformations of vulva	0.010	0.990	0.000
Q52.6 Congenital malformation of clitoris	0.010	0.990	0.000
Q52.4 Other congenital malformations of vagina	0.010	0.990	0.000
Q52.3 Imperforate hymen	0.010	0.990	0.000
Q52.2 Congenital rectovaginal fistula	0.010	0.990	0.000
Q52.0 Congenital absence of vagina	0.010	0.990	0.000
Q34 Other congenital malformations of respiratory system	0.010	0.990	0.000
Q33 Congenital malformations of lung	0.010	0.990	0.000
Q32 Congenital malformations of trachea and bronchus	0.010	0.990	0.000
Q31 Congenital malformations of larynx	0.010	0.990	0.000
Q30 Congenital malformations of nose	0.010	0.990	0.000
Q56.4 Indeterminate sex, unspecified	0.010	0.990	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.010	0.990	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.010	0.990	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.010	0.990	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.010	0.990	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.010	0.990	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.010	0.990	0.000
Q84 Other congenital malformations of integument	0.010	0.990	0.000
Q81 Epidermolysis bullosa	0.010	0.990	0.000
Q80 Congenital ichthyosis	0.010	0.990	0.000
M14.6 Neuropathic arthropathy	0.009	0.990	0.001
Q90 Down's syndrome	0.010	0.990	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.010	0.990	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.010	0.990	0.000
Q40.1 Congenital hiatus hernia	0.010	0.990	0.000
Q23 Congenital malformations of aortic and mitral valves	0.010	0.990	0.000
M12.3 Palindromic rheumatism	0.007	0.990	0.002
Q06 Other congenital malformations of spinal cord	0.010	0.990	0.000
Q03 Congenital hydrocephalus	0.010	0.990	0.000
Q01 Encephalocele	0.010	0.990	0.000
Q00 Anencephaly and similar malformations	0.010	0.990	0.000
Q02 Microcephaly	0.010	0.990	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.010	0.990	0.000
M06.34 Rheumatoid nodule (Hand)	0.001	0.990	0.009
Q45.9 Congenital malformation of digestive system, unspecified	0.009	0.990	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.009	0.990	0.000
Q45.2 Congenital pancreatic cyst	0.009	0.990	0.000
Q45.1 Annular pancreas	0.009	0.990	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.009	0.990	0.000
Q82.5 Congenital nonneoplastic naevus	0.010	0.990	0.000
M14.2 Diabetic arthropathy	0.007	0.990	0.002
M07 Psoriatic and enteropathic arthropathies	0.005	0.990	0.004
Q12.9 Congenital lens malformation, unspecified	0.009	0.990	0.000
Q12.8 Other congenital lens malformations	0.009	0.990	0.000
Q12.4 Spherophakia	0.009	0.990	0.000
Q12.3 Congenital aphakia	0.009	0.990	0.000
Q12.2 Coloboma of lens	0.009	0.990	0.000
Q12.1 Congenital displaced lens	0.009	0.990	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.009	0.990	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.009	0.990	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.005	0.991	0.004
M09.2 Juvenile arthritis in ulcerative colitis	0.005	0.991	0.004
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.005	0.991	0.004
M09.0 Juvenile arthritis in psoriasis	0.005	0.991	0.004
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.001	0.991	0.008
M08.9 Juvenile arthritis, unspecified	0.005	0.991	0.004
M08.8 Other juvenile arthritis	0.005	0.991	0.004
M08.4 Pauciarticular juvenile arthritis	0.005	0.991	0.004
M08.3 Juvenile polyarthritis (seronegative)	0.005	0.991	0.004
M08.2 Juvenile arthritis with systemic onset	0.005	0.991	0.004
M08.1 Juvenile ankylosing spondylitis	0.005	0.991	0.004
M14.8 Arthropathies in other specified diseases classified elsewhere	0.007	0.991	0.003
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.007	0.991	0.003
M14.4 Arthropathy in amyloidosis	0.007	0.991	0.003
M14.3 Lipoid dermatoarthritis	0.007	0.991	0.003
M14.1 Crystal arthropathy in other metabolic disorders	0.007	0.991	0.003
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.007	0.991	0.003
Q15.0 Congenital glaucoma	0.009	0.991	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.002	0.991	0.008
M12.8 Other specific arthropathies, not elsewhere classified	0.006	0.991	0.003
M12.4 Intermittent hydrarthrosis	0.006	0.991	0.003
M12.1 Kaschin-Beck disease	0.006	0.991	0.003
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.006	0.991	0.003
Q52.1 Doubling of vagina	0.009	0.991	0.000
Q17 Other congenital malformations of ear	0.009	0.991	0.000
M08.0 Juvenile rheumatoid arthritis	0.005	0.991	0.004
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.009	0.991	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.009	0.991	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.009	0.991	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.009	0.991	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.009	0.991	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.009	0.991	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.009	0.991	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.009	0.991	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.009	0.991	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.009	0.991	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.009	0.991	0.000
Q61.9 Cystic kidney disease, unspecified	0.009	0.991	0.000
Q89.3 Situs inversus	0.009	0.991	0.000
Q04 Other congenital malformations of brain	0.009	0.991	0.000
Q64 Other congenital malformations of urinary system	0.009	0.991	0.000
Q85 Phakomatoses, not elsewhere classified	0.009	0.991	0.000
M12.5 Traumatic arthropathy	0.006	0.991	0.003
Q61.4 Renal dysplasia	0.009	0.991	0.000
I08 Multiple valve diseases	0.000	0.991	0.009
M12.2 Villonodular synovitis (pigmented)	0.006	0.991	0.003
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.009	0.991	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.009	0.991	0.000
Q98.7 Male with sex chromosome mosaicism	0.009	0.991	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.009	0.991	0.000
Q98.5 Karyotype 47,XYY	0.009	0.991	0.000
Q98.3 Other male with 46,XX karyotype	0.009	0.991	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.009	0.991	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.009	0.991	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.009	0.991	0.000
Q40.2 Other specified congenital malformations of stomach	0.009	0.991	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.009	0.991	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.002	0.991	0.007
M05.88 Other seropositive rheumatoid arthritis (Other)	0.002	0.991	0.007
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.002	0.991	0.007
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.002	0.991	0.007
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.002	0.991	0.007
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.002	0.991	0.007
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.002	0.991	0.007
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.002	0.991	0.007
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.002	0.991	0.007
Q61.5 Medullary cystic kidney	0.009	0.991	0.000
Q82.2 Mastocytosis	0.009	0.991	0.000
Q89.9 Congenital malformation, unspecified	0.009	0.991	0.000
Q89.8 Other specified congenital malformations	0.009	0.991	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.009	0.991	0.000
Q89.4 Conjoined twins	0.009	0.991	0.000
Q89.1 Congenital malformations of adrenal gland	0.009	0.991	0.000
Q89.0 Congenital malformations of spleen	0.009	0.991	0.000
Q05 Spina bifida	0.009	0.991	0.000
Q18 Other congenital malformations of face and neck	0.009	0.991	0.000
O63 Long labour	0.000	0.991	0.009
Q11.1 Other anophthalmos	0.009	0.991	0.000
M05.09 Felty's syndrome (Site unspecified)	0.002	0.991	0.007
M05.08 Felty's syndrome (Other)	0.002	0.991	0.007
M05.07 Felty's syndrome (Ankle and foot)	0.002	0.991	0.007
M05.06 Felty's syndrome (Lower leg)	0.002	0.991	0.007
M05.05 Felty's syndrome (Pelvic region and thigh)	0.002	0.991	0.007
M05.04 Felty's syndrome (Hand)	0.002	0.991	0.007
M05.03 Felty's syndrome (Forearm)	0.002	0.991	0.007
M05.02 Felty's syndrome (Upper arm)	0.002	0.991	0.007
M05.01 Felty's syndrome (Shoulder region)	0.002	0.991	0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations