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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2596480
log Bayes Factor = 21.5933
Chromosome 6   position 31,425,985  (GRCh37) Explore rs2596480 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.001 0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.003 0.997
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.005 0.995
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.010 0.990
E10.9 Without complications
0.000 0.011 0.989
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.015 0.985
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.017 0.983
Chapter I Certain infectious and parasitic diseases
0.000 0.018 0.982
M07 Psoriatic and enteropathic arthropathies
0.000 0.024 0.976
E10.3 With ophthalmic complications
0.000 0.029 0.971
L57.0 Actinic keratosis
0.000 0.030 0.970
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.031 0.969
D50-D53 Nutritional anaemias
0.000 0.034 0.966
M07.3 Other psoriatic arthropathies
0.000 0.041 0.959
D50 Iron deficiency anaemia
0.000 0.043 0.957
D50.9 Iron deficiency anaemia, unspecified
0.000 0.048 0.952
B25-B34 Other viral diseases
0.000 0.048 0.952
B35-B49 Mycoses
0.000 0.052 0.948
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.055 0.945
D60-D64 Aplastic and other anaemias
0.000 0.059 0.941
L20-L30 Dermatitis and eczema
0.000 0.063 0.937
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.064 0.936
B37 Candidiasis
0.000 0.071 0.929
M35 Other systemic involvement of connective tissue
0.000 0.072 0.928
M20-M25 Other joint disorders
0.000 0.072 0.928
M35.3 Polymyalgia rheumatica
0.000 0.075 0.925
E50-E64 Other nutritional deficiencies
0.000 0.078 0.922
B37.8 Candidiasis of other sites
0.000 0.078 0.922
B34 Viral infection of unspecified site
0.000 0.079 0.921
D80-D89 Certain disorders involving the immune mechanism
0.000 0.080 0.920
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.082 0.918
L08 Other local infections of skin and subcutaneous tissue
0.000 0.084 0.916
D64 Other anaemias
0.000 0.086 0.914
E10.1 With ketoacidosis
0.000 0.086 0.914
M06.0 Seronegative rheumatoid arthritis
0.000 0.087 0.913
E06 Thyroiditis
0.000 0.091 0.909
C44 Other malignant neoplasms of skin
0.000 0.101 0.899
B34.9 Viral infection, unspecified
0.000 0.102 0.898
C44.3 Skin of other and unspecified parts of face
0.000 0.103 0.897
D64.9 Anaemia, unspecified
0.000 0.105 0.895
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.106 0.894
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.107 0.893
C44.4 Skin of scalp and neck
0.000 0.109 0.891
Chapter VIII Diseases of the ear and mastoid process
0.000 0.113 0.887
E65-E68 Obesity and other hyperalimentation
0.000 0.121 0.879
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.121 0.879
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.121 0.879
D86 Sarcoidosis
0.000 0.126 0.874
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.129 0.871
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.130 0.870
M45-M49 Spondylopathies
0.000 0.135 0.865
Chapter II Neoplasms
0.000 0.140 0.860
M05 Seropositive rheumatoid arthritis
0.000 0.140 0.860
L29 Pruritus
0.000 0.142 0.858
E53 Deficiency of other B group vitamins
0.000 0.148 0.852
E10.4 With neurological complications
0.000 0.149 0.851
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.154 0.846
M45 Ankylosing spondylitis
0.000 0.159 0.841
E06.3 Autoimmune thyroiditis
0.000 0.160 0.840
L30 Other dermatitis
0.000 0.173 0.827
B99-B99 Other infectious diseases
0.000 0.176 0.824
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.177 0.823
D86.9 Sarcoidosis, unspecified
0.000 0.177 0.823
M35.0 Sicca syndrome [Sjogren]
0.000 0.178 0.822
B35 Dermatophytosis
0.000 0.178 0.822
L29.0 Pruritus ani
0.000 0.180 0.819
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.182 0.818
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.182 0.818
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.000 0.183 0.817
L40.0 Psoriasis vulgaris
0.000 0.186 0.814
M95.0 Acquired deformity of nose
0.000 0.187 0.813
C44.1 Skin of eyelid, including canthus
0.000 0.189 0.811
E14 Unspecified diabetes mellitus
0.000 0.190 0.810
H65-H75 Diseases of middle ear and mastoid
0.000 0.191 0.809
E66 Obesity
0.000 0.192 0.808
E53.8 Deficiency of other specified B group vitamins
0.000 0.197 0.803
R47-R49 Symptoms and signs involving speech and voice
0.000 0.204 0.796
E66.8 Other obesity
0.000 0.206 0.794
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.206 0.794
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.210 0.790
H72 Perforation of tympanic membrane
0.000 0.211 0.789
E10.5 With peripheral circulatory complications
0.000 0.215 0.785
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.217 0.783
C64-C68 Malignant neoplasms of urinary tract
0.000 0.221 0.779
E10.2 With renal complications
0.000 0.227 0.773
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.229 0.771
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.000 0.231 0.769
R41 Other symptoms and signs involving cognitive functions and awareness
0.000 0.233 0.767
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.233 0.766
B25 Cytomegaloviral disease
0.000 0.236 0.764
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.000 0.236 0.764
R47 Speech disturbances, not elsewhere classified
0.000 0.237 0.763
M34 Systemic sclerosis
0.000 0.239 0.761
M00-M03 Infectious arthropathies
0.000 0.240 0.760
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.240 0.760
M35.7 Hypermobility syndrome
0.000 0.242 0.758
M22 Disorders of patella
0.000 0.243 0.757
M60-M63 Disorders of muscles
0.000 0.244 0.756
C44.7 Skin of lower limb, including hip
0.000 0.247 0.753
B37.0 Candidal stomatitis
0.000 0.249 0.751
R41.0 Disorientation, unspecified
0.000 0.250 0.750
E55 Vitamin D deficiency
0.000 0.252 0.748
Chapter IX Diseases of the circulatory system
0.000 0.258 0.742
D86.0 Sarcoidosis of lung
0.000 0.258 0.742
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.258 0.742
L30.8 Other specified dermatitis
0.000 0.259 0.741
I60-I69 Cerebrovascular diseases
0.000 0.264 0.736
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.264 0.736
D55-D59 Haemolytic anaemias
0.000 0.266 0.734
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.266 0.734
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.269 0.731
R47.0 Dysphasia and aphasia
0.000 0.270 0.730
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.272 0.728
R41.3 Other amnesia
0.000 0.272 0.728
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.272 0.728
H80-H83 Diseases of inner ear
0.000 0.278 0.722
C44.2 Skin of ear and external auricular canal
0.000 0.281 0.719
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M12 Other specific arthropathies
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
M46 Other inflammatory spondylopathies
0.000 0.284 0.715
B99 Other and unspecified infectious diseases
0.000 0.290 0.710
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.290 0.710
L58 Radiodermatitis
0.000 0.290 0.710
L55 Sunburn
0.000 0.290 0.710
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.294 0.706
L04 Acute lymphadenitis
0.000 0.294 0.706
L01 Impetigo
0.000 0.294 0.706
L00 Staphylococcal scalded skin syndrome
0.000 0.294 0.706
R91 Abnormal findings on diagnostic imaging of lung
0.000 0.295 0.705
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.295 0.705
L57.5 Actinic granuloma
0.000 0.295 0.705
L57.3 Poikiloderma of Civatte
0.000 0.295 0.705
L57.2 Cutis rhomboidalis nuchae
0.000 0.295 0.705
L57.1 Actinic reticuloid
0.000 0.295 0.705
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.296 0.704
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.296 0.704
A75-A79 Rickettsioses
0.000 0.296 0.704
A70-A74 Other diseases caused by chlamydiae
0.000 0.296 0.704
A65-A69 Other spirochaetal diseases
0.000 0.296 0.704
A20-A28 Certain zoonotic bacterial diseases
0.000 0.296 0.704
A15-A19 Tuberculosis
0.000 0.296 0.704
R26 Abnormalities of gait and mobility
0.000 0.297 0.703
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.297 0.702
I60 Subarachnoid haemorrhage
0.000 0.298 0.702
M11 Other crystal arthropathies
0.000 0.298 0.702
M07.6 Other enteropathic arthropathies
0.000 0.300 0.700
M07.5 Arthropathy in ulcerative colitis
0.000 0.300 0.700
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.300 0.700
M07.2 Psoriatic spondylitis
0.000 0.300 0.700
M07.1 Arthritis mutilans
0.000 0.300 0.700
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.300 0.700
L27 Dermatitis due to substances taken internally
0.000 0.300 0.700
B50-B64 Protozoal diseases
0.000 0.301 0.699
Chapter V Mental and behavioural disorders
0.000 0.301 0.699
H72.0 Central perforation of tympanic membrane
0.000 0.302 0.698
R49 Voice disturbances
0.000 0.303 0.697
E40-E46 Malnutrition
0.000 0.303 0.696
E13 Other specified diabetes mellitus
0.000 0.304 0.696
M14 Arthropathies in other diseases classified elsewhere
0.000 0.305 0.695
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.305 0.694
L05 Pilonidal cyst
0.000 0.307 0.693
C67 Malignant neoplasm of bladder
0.000 0.309 0.691
B35.1 Tinea unguium
0.000 0.309 0.691
L10-L14 Bullous disorders
0.000 0.311 0.689
M07.38 Other psoriatic arthropathies (Other)
0.000 0.312 0.687
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.312 0.687
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.312 0.687
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.312 0.687
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.312 0.687
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.312 0.687
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.312 0.687
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.312 0.687
Chapter XXII Codes for special purposes
0.000 0.314 0.686
D50.1 Sideropenic dysphagia
0.000 0.314 0.686
R47.1 Dysarthria and anarthria
0.000 0.315 0.685
E03.8 Other specified hypothyroidism
0.000 0.317 0.683
B33 Other viral diseases, not elsewhere classified
0.000 0.318 0.682
B30 Viral conjunctivitis
0.000 0.318 0.682
B27 Infectious mononucleosis
0.000 0.318 0.682
B26 Mumps
0.000 0.318 0.682
D61 Other aplastic anaemias
0.000 0.320 0.680
B48 Other mycoses, not elsewhere classified
0.000 0.320 0.679
B47 Mycetoma
0.000 0.320 0.679
B46 Zygomycosis
0.000 0.320 0.679
B45 Cryptococcosis
0.000 0.320 0.679
B43 Chromomycosis and phaeomycotic abscess
0.000 0.320 0.679
B42 Sporotrichosis
0.000 0.320 0.679
B41 Paracoccidioidomycosis
0.000 0.320 0.679
B40 Blastomycosis
0.000 0.320 0.679
B39 Histoplasmosis
0.000 0.320 0.679
B38 Coccidioidomycosis
0.000 0.320 0.679
B36 Other superficial mycoses
0.000 0.320 0.679
A30-A49 Other bacterial diseases
0.000 0.322 0.677
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.323 0.677
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.323 0.677
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.326 0.674
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.326 0.674
L24 Irritant contact dermatitis
0.000 0.328 0.672
L21 Seborrhoeic dermatitis
0.000 0.328 0.672
L26 Exfoliative dermatitis
0.000 0.328 0.672
L22 Diaper [napkin] dermatitis
0.000 0.328 0.672
I63 Cerebral infarction
0.000 0.328 0.672
C34 Malignant neoplasm of bronchus and lung
0.000 0.329 0.671
B65-B83 Helminthiases
0.000 0.331 0.669
E14.9 Without complications
0.000 0.332 0.668
R93 Abnormal findings on diagnostic imaging of other body structures
0.000 0.332 0.668
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.332 0.667
A00-A09 Intestinal infectious diseases
0.000 0.333 0.667
B37.7 Candidal septicaemia
0.000 0.334 0.666
B37.6 Candidal endocarditis
0.000 0.334 0.666
B37.5 Candidal meningitis
0.000 0.334 0.666
B37.2 Candidiasis of skin and nail
0.000 0.334 0.666
D64.8 Other specified anaemias
0.000 0.334 0.666
I67 Other cerebrovascular diseases
0.000 0.334 0.666
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.334 0.666
M35.8 Other specified systemic involvement of connective tissue
0.000 0.334 0.666
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.334 0.666
M35.5 Multifocal fibrosclerosis
0.000 0.334 0.666
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.334 0.666
M35.2 Behcet's disease
0.000 0.334 0.666
M35.1 Other overlap syndromes
0.000 0.334 0.666
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.335 0.665
M32 Systemic lupus erythematosus
0.000 0.335 0.665
E06.9 Thyroiditis, unspecified
0.000 0.336 0.664
I69 Sequelae of cerebrovascular disease
0.000 0.336 0.664
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.338 0.662
B35.3 Tinea pedis
0.000 0.339 0.661
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.339 0.661
E63 Other nutritional deficiencies
0.000 0.339 0.661
E56 Other vitamin deficiencies
0.000 0.339 0.661
E51 Thiamine deficiency
0.000 0.339 0.661
E50 Vitamin A deficiency
0.000 0.339 0.661
E60 Dietary zinc deficiency
0.000 0.339 0.661
E59 Dietary selenium deficiency
0.000 0.339 0.661
E58 Dietary calcium deficiency
0.000 0.339 0.661
E54 Ascorbic acid deficiency
0.000 0.339 0.661
E52 Niacin deficiency [pellagra]
0.000 0.339 0.661
B34.8 Other viral infections of unspecified site
0.000 0.340 0.660
B34.4 Papovirus infection, unspecified
0.000 0.340 0.660
B34.3 Parvovirus infection, unspecified
0.000 0.340 0.660
B34.2 Coronavirus infection, unspecified
0.000 0.340 0.660
B34.1 Enterovirus infection, unspecified
0.000 0.340 0.660
B34.0 Adenovirus infection, unspecified
0.000 0.340 0.660
D84 Other immunodeficiencies
0.000 0.340 0.660
D83 Common variable immunodeficiency
0.000 0.340 0.660
D82 Immunodeficiency associated with other major defects
0.000 0.340 0.660
D81 Combined immunodeficiencies
0.000 0.340 0.660
A80-A89 Viral infections of the central nervous system
0.000 0.341 0.659
M06.3 Rheumatoid nodule
0.000 0.342 0.658
M30 Polyarteritis nodosa and related conditions
0.000 0.342 0.658
R26.8 Other and unspecified abnormalities of gait and mobility
0.000 0.343 0.657
H60-H62 Diseases of external ear
0.000 0.343 0.657
E10.6 With other specified complications
0.000 0.343 0.657
L08.1 Erythrasma
0.000 0.343 0.657
L08.0 Pyoderma
0.000 0.343 0.657
D64.4 Congenital dyserythropoietic anaemia
0.000 0.344 0.655
D64.3 Other sideroblastic anaemias
0.000 0.344 0.655
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.344 0.655
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.344 0.655
D64.0 Hereditary sideroblastic anaemia
0.000 0.344 0.655
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.345 0.655
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.345 0.655
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.345 0.655
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.345 0.655
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.345 0.655
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.345 0.655
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.345 0.655
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.000 0.347 0.653
L28 Lichen simplex chronicus and prurigo
0.000 0.348 0.652
E06.5 Other chronic thyroiditis
0.000 0.348 0.651
E06.4 Drug-induced thyroiditis
0.000 0.348 0.651
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.348 0.651
E06.1 Subacute thyroiditis
0.000 0.348 0.651
E06.0 Acute thyroiditis
0.000 0.348 0.651
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.351 0.648
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.352 0.648
L20 Atopic dermatitis
0.000 0.353 0.647
B37.1 Pulmonary candidiasis
0.000 0.353 0.647
M31 Other necrotising vasculopathies
0.000 0.353 0.647
D80 Immunodeficiency with predominantly antibody defects
0.000 0.354 0.646
L29.9 Pruritus, unspecified
0.000 0.355 0.645
C44.8 Overlapping lesion of skin
0.000 0.355 0.645
E20-E35 Disorders of other endocrine glands
0.000 0.356 0.644
L25 Unspecified contact dermatitis
0.000 0.356 0.644
M34.9 Systemic sclerosis, unspecified
0.000 0.358 0.642
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.359 0.641
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.359 0.641
M99 Biomechanical lesions, not elsewhere classified
0.000 0.359 0.640
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.360 0.640
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.362 0.638
I67.8 Other specified cerebrovascular diseases
0.000 0.367 0.633
M06.4 Inflammatory polyarthropathy
0.000 0.368 0.632
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.368 0.631
I05-I09 Chronic rheumatic heart diseases
0.000 0.369 0.631
E67 Other hyperalimentation
0.000 0.369 0.630
E68 Sequelae of hyperalimentation
0.000 0.369 0.630
R41.2 Retrograde amnesia
0.000 0.370 0.630
B25.9 Cytomegaloviral disease, unspecified
0.000 0.371 0.629
H65 Nonsuppurative otitis media
0.000 0.372 0.628
L23 Allergic contact dermatitis
0.000 0.372 0.628
L57.4 Cutis laxa senilis
0.000 0.372 0.628
C34.9 Bronchus or lung, unspecified
0.000 0.372 0.628
D86.3 Sarcoidosis of skin
0.000 0.373 0.627
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.373 0.627
D86.1 Sarcoidosis of lymph nodes
0.000 0.373 0.627
H73 Other disorders of tympanic membrane
0.000 0.376 0.624
M22.8 Other disorders of patella
0.000 0.377 0.623
E55.9 Vitamin D deficiency, unspecified
0.000 0.377 0.623
D53 Other nutritional anaemias
0.000 0.377 0.623
B15-B19 Viral hepatitis
0.000 0.379 0.621
E70-E90 Metabolic disorders
0.000 0.379 0.621
I63.9 Cerebral infarction, unspecified
0.000 0.379 0.621
M05.8 Other seropositive rheumatoid arthritis
0.000 0.383 0.616
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.383 0.616
M05.2 Rheumatoid vasculitis
0.000 0.383 0.616
M05.1 Rheumatoid lung disease
0.000 0.383 0.616
M05.0 Felty's syndrome
0.000 0.383 0.616
H80 Otosclerosis
0.000 0.384 0.616
M33 Dermatopolymyositis
0.000 0.384 0.616
D52 Folate deficiency anaemia
0.000 0.384 0.616
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.384 0.616
L29.8 Other pruritus
0.000 0.385 0.615
L29.3 Anogenital pruritus, unspecified
0.000 0.385 0.615
L29.1 Pruritus scroti
0.000 0.385 0.615
B24 Unspecified human immunodeficiency virus [HIV] disease
0.000 0.388 0.612
I62 Other nontraumatic intracranial haemorrhage
0.000 0.388 0.612
E53.9 Vitamin B deficiency, unspecified
0.000 0.389 0.611
E53.1 Pyridoxine deficiency
0.000 0.389 0.611
E53.0 Riboflavin deficiency
0.000 0.389 0.611
L30.9 Dermatitis, unspecified
0.000 0.390 0.610
R90 Abnormal findings on diagnostic imaging of central nervous system
0.000 0.390 0.610
E61 Deficiency of other nutrient elements
0.000 0.392 0.608
M49 Spondylopathies in diseases classified elsewhere
0.000 0.392 0.608
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.392 0.608
C66 Malignant neoplasm of ureter
0.000 0.392 0.607
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.000 0.393 0.607
M95.8 Other specified acquired deformities of musculoskeletal system
0.000 0.393 0.607
M95.5 Acquired deformity of pelvis
0.000 0.393 0.607
M95.4 Acquired deformity of chest and rib
0.000 0.393 0.607
M95.3 Acquired deformity of neck
0.000 0.393 0.607
M95.2 Other acquired deformity of head
0.000 0.393 0.607
M95.1 Cauliflower ear
0.000 0.393 0.607
E27 Other disorders of adrenal gland
0.000 0.395 0.605
M91-M94 Chondropathies
0.000 0.396 0.604
L42 Pityriasis rosea
0.000 0.397 0.603
M62 Other disorders of muscle
0.000 0.397 0.603
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.397 0.603
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.397 0.603
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.397 0.603
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.397 0.603
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.397 0.603
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.397 0.603
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.397 0.603
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.397 0.603
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.397 0.603
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.000 0.399 0.601
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.000 0.399 0.601
C67.2 Lateral wall of bladder
0.000 0.399 0.601
E05.9 Thyrotoxicosis, unspecified
0.000 0.400 0.600
R49.0 Dysphonia
0.000 0.400 0.600
E66.0 Obesity due to excess calories
0.000 0.402 0.598
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.404 0.596
C73 Malignant neoplasm of thyroid gland
0.000 0.404 0.596
H70 Mastoiditis and related conditions
0.000 0.405 0.595
I69.3 Sequelae of cerebral infarction
0.000 0.405 0.595
B37.4 Candidiasis of other urogenital sites
0.000 0.406 0.594
M22.3 Other derangements of patella
0.000 0.406 0.593
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.407 0.593
L30.5 Pityriasis alba
0.000 0.407 0.593
L30.4 Erythema intertrigo
0.000 0.407 0.593
L30.3 Infective dermatitis
0.000 0.407 0.593
L30.2 Cutaneous autosensitisation
0.000 0.407 0.593
L30.1 Dyshidrosis [pompholyx]
0.000 0.407 0.593
L30.0 Nummular dermatitis
0.000 0.407 0.593
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.408 0.592
C65 Malignant neoplasm of renal pelvis
0.000 0.409 0.591
B35.9 Dermatophytosis, unspecified
0.000 0.411 0.589
B35.8 Other dermatophytoses
0.000 0.411 0.589
B35.6 Tinea cruris
0.000 0.411 0.589
B35.5 Tinea imbricata
0.000 0.411 0.589
B35.4 Tinea corporis
0.000 0.411 0.589
B35.2 Tinea manuum
0.000 0.411 0.589
B35.0 Tinea barbae and tinea capitis
0.000 0.411 0.589
M00 Pyogenic arthritis
0.000 0.411 0.589
B37.3 Candidiasis of vulva and vagina
0.000 0.411 0.589
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.411 0.588
E14.3 With ophthalmic complications
0.000 0.412 0.588
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.000 0.413 0.587
D62 Acute posthaemorrhagic anaemia
0.000 0.413 0.587
B37.9 Candidiasis, unspecified
0.000 0.413 0.586
R95-R99 Ill-defined and unknown causes of mortality
0.000 0.414 0.586
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.415 0.585
L50-L54 Urticaria and erythema
0.000 0.415 0.584
R26.2 Difficulty in walking, not elsewhere classified
0.000 0.416 0.584
M80-M85 Disorders of bone density and structure
0.001 0.417 0.582
E14.8 With unspecified complications
0.000 0.419 0.580
E14.7 With multiple complications
0.000 0.419 0.580
E14.6 With other specified complications
0.000 0.419 0.580
E14.5 With peripheral circulatory complications
0.000 0.419 0.580
E14.4 With neurological complications
0.000 0.419 0.580
E14.2 Withrenal complications
0.000 0.419 0.580
E14.1 With ketoacidosis
0.000 0.419 0.580
E14.0 With coma
0.000 0.419 0.580
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.420 0.580
H68 Eustachian salpingitis and obstruction
0.000 0.420 0.580
H67 Otitis media in diseases classified elsewhere
0.000 0.420 0.580
E66.1 Drug-induced obesity
0.000 0.421 0.579
E65 Localised adiposity
0.000 0.421 0.579
I60.8 Other subarachnoid haemorrhage
0.000 0.425 0.575
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.425 0.575
E11 Non-insulin-dependent diabetes mellitus
0.000 0.425 0.575
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.427 0.573
D86.8 Sarcoidosis of other and combined sites
0.000 0.427 0.573
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.427 0.573
R26.3 Immobility
0.000 0.427 0.573
D59 Acquired haemolytic anaemia
0.000 0.427 0.573
H83 Other diseases of inner ear
0.000 0.427 0.573
L43 Lichen planus
0.000 0.427 0.573
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.429 0.571
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.000 0.429 0.571
D51 Vitamin B12 deficiency anaemia
0.000 0.430 0.570
E05.5 Thyroid crisis or storm
0.000 0.431 0.569
E05.4 Thyrotoxicosis factitia
0.000 0.431 0.569
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.431 0.569
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.431 0.569
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.433 0.567
H72.1 Attic perforation of tympanic membrane
0.000 0.434 0.566
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.435 0.565
E07 Other disorders of thyroid
0.000 0.437 0.562
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.438 0.562
M22.2 Patellofemoral disorders
0.000 0.439 0.561
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.439 0.561
A02 Other Salmonella infections
0.000 0.439 0.561
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.440 0.560
C51-C58 Malignant neoplasms of female genital organs
0.000 0.440 0.560
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.441 0.559
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.442 0.558
C44.6 Skin of upper limb, including shoulder
0.000 0.442 0.558
I05 Rheumatic mitral valve diseases
0.000 0.443 0.557
A08 Viral and other specified intestinal infections
0.000 0.443 0.557
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.443 0.557
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.000 0.443 0.557
D50.8 Other iron deficiency anaemias
0.000 0.443 0.557
C64 Malignant neoplasm of kidney, except renal pelvis
0.000 0.444 0.556
R49.8 Other and unspecified voice disturbances
0.000 0.446 0.553
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.000 0.449 0.551
M10 Gout
0.000 0.449 0.551
D10-D36 Benign neoplasms
0.000 0.449 0.551
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.450 0.550
R41.1 Anterograde amnesia
0.000 0.450 0.550
A41 Other septicaemia
0.000 0.450 0.550
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions
0.000 0.450 0.550
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases
0.000 0.450 0.550
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms
0.000 0.450 0.550
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
0.000 0.450 0.550
E27.1 Primary adrenocortical insufficiency
0.000 0.450 0.550
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.452 0.548
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.452 0.548

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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