TreeWAS – Variant ID: rs2596502

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.001	0.999
L40 Psoriasis	0.872	0.128	0.000
L40.8 Other psoriasis	0.757	0.243	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.244	0.756
L40.0 Psoriasis vulgaris	0.729	0.271	0.000
L40.1 Generalised pustular psoriasis	0.726	0.274	0.000
I10 Essential (primary) hypertension	0.680	0.320	0.000
L40.5 Arthropathic psoriasis	0.677	0.323	0.000
L40.4 Guttate psoriasis	0.625	0.375	0.000
L40.2 Acrodermatitis continua	0.625	0.375	0.000
E03 Other hypothyroidism	0.000	0.378	0.622
L40.3 Pustulosis palmaris et plantaris	0.600	0.400	0.000
E00-E07 Disorders of thyroid gland	0.000	0.444	0.555
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.450	0.550
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.470	0.530
E05.9 Thyrotoxicosis, unspecified	0.000	0.484	0.516
M35 Other systemic involvement of connective tissue	0.000	0.525	0.475
T36-T50 Poisoning by drugs, medicaments and biological substances	0.467	0.533	0.000
E03.5 Myxoedema coma	0.000	0.554	0.446
E03.4 Atrophy of thyroid (acquired)	0.000	0.554	0.446
E03.3 Postinfectious hypothyroidism	0.000	0.554	0.446
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.444	0.556	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.443	0.557	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.442	0.558	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.442	0.558	0.000
T39.1 4-Aminophenol derivatives	0.431	0.569	0.000
E07 Other disorders of thyroid	0.000	0.575	0.425
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.585	0.415
T40.2 Other opioids	0.413	0.587	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.413	0.587	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.412	0.588	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.405	0.595	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.405	0.595	0.000
E03.1 Congenital hypothyroidism without goitre	0.000	0.600	0.400
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.602	0.398
E00 Congenital iodine-deficiency syndrome	0.000	0.602	0.398
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.604	0.395
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.395	0.605	0.000
E05.5 Thyroid crisis or storm	0.000	0.606	0.394
E05.4 Thyrotoxicosis factitia	0.000	0.606	0.394
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.606	0.394
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.606	0.394
M35.7 Hypermobility syndrome	0.000	0.606	0.394
M35.3 Polymyalgia rheumatica	0.000	0.609	0.391
E05.8 Other thyrotoxicosis	0.000	0.611	0.389
T42.4 Benzodiazepines	0.386	0.614	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.381	0.619	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.381	0.619	0.000
E03.8 Other specified hypothyroidism	0.000	0.625	0.374
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.627	0.373
E07.8 Other specified disorders of thyroid	0.000	0.630	0.370
T40.6 Other and unspecified narcotics	0.367	0.633	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.361	0.639	0.000
T50.8 Diagnostic agents	0.360	0.640	0.000
T46.1 Calcium-channel blockers	0.353	0.647	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.350	0.650	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.349	0.651	0.000
M35.8 Other specified systemic involvement of connective tissue	0.000	0.652	0.348
T40.1 Heroin	0.344	0.655	0.000
E06 Thyroiditis	0.000	0.657	0.343
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.341	0.659	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.659	0.341
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.659	0.341
M35.5 Multifocal fibrosclerosis	0.000	0.659	0.341
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.659	0.341
M35.1 Other overlap syndromes	0.000	0.660	0.340
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.339	0.661	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.338	0.662	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.335	0.665	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.335	0.665	0.000
T40.5 Cocaine	0.333	0.667	0.000
T36 Poisoning by systemic antibiotics	0.330	0.670	0.000
T39.0 Salicylates	0.324	0.676	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.319	0.681	0.000
T39.4 Antirheumatics, not elsewhere classified	0.319	0.681	0.000
T39.2 Pyrazolone derivatives	0.319	0.681	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.317	0.682	0.000
T40.8 Lysergide [LSD]	0.317	0.682	0.000
T40.7 Cannabis (derivatives)	0.317	0.682	0.000
T40.3 Methadone	0.317	0.682	0.000
T40.0 Opium	0.317	0.682	0.000
T50.7 Analeptics and opioid receptor antagonists	0.317	0.683	0.000
T50.5 Appetite depressants	0.317	0.683	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.317	0.683	0.000
T50.1 Loop [high-ceiling] diuretics	0.317	0.683	0.000
T50.0 Mineralocorticoids and their antagonists	0.317	0.683	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.317	0.683	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.317	0.683	0.000
T46.7 Peripheral vasodilators	0.317	0.683	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.317	0.683	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.317	0.683	0.000
M35.2 Behcet's disease	0.000	0.683	0.317
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.317	0.683	0.000
T50.4 Drugs affecting uric acid metabolism	0.314	0.686	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.001	0.688	0.311
T46.3 Coronary vasodilators, not elsewhere classified	0.305	0.694	0.000
E07.1 Dyshormogenetic goitre	0.000	0.695	0.305
E07.0 Hypersecretion of calcitonin	0.000	0.695	0.305
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.304	0.695	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.295	0.705	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.294	0.706	0.000
T45.0 Antiallergic and antiemetic drugs	0.292	0.708	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.291	0.709	0.000
T42.3 Barbiturates	0.291	0.709	0.000
T42.2 Succinimides and oxazolidinediones	0.291	0.709	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.288	0.711	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.288	0.712	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.714	0.286
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.714	0.286
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.714	0.286
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.714	0.286
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.714	0.286
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.714	0.286
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.714	0.286
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.714	0.286
T38.9 Other and unspecified hormone antagonists	0.283	0.717	0.000
T38.7 Androgens and anabolic congeners	0.283	0.717	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.283	0.717	0.000
T38.5 Other oestrogens and progestogens	0.283	0.717	0.000
T38.4 Oral contraceptives	0.283	0.717	0.000
T38.2 Antithyroid drugs	0.283	0.717	0.000
T38.0 Glucocorticoids and synthetic analogues	0.283	0.717	0.000
T38.1 Thyroid hormones and substitutes	0.281	0.719	0.000
T42.1 Iminostilbenes	0.280	0.720	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.273	0.727	0.000
T48.5 Anti-common-cold drugs	0.273	0.727	0.000
T48.4 Expectorants	0.273	0.727	0.000
T48.3 Antitussives	0.273	0.727	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.273	0.727	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.273	0.727	0.000
T48.0 Oxytocic drugs	0.273	0.727	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.273	0.727	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.273	0.727	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.273	0.727	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.273	0.727	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.273	0.727	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.273	0.727	0.000
T44.0 Anticholinesterase agents	0.273	0.727	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.265	0.735	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.264	0.736	0.000
T42.0 Hydantoin derivatives	0.262	0.738	0.000
T40.4 Other synthetic narcotics	0.261	0.739	0.000
E04 Other non-toxic goitre	0.000	0.739	0.261
T45.5 Anticoagulants	0.255	0.745	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.251	0.749	0.000
T45.8 Other primarily systemic and haematological agents	0.251	0.749	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.251	0.749	0.000
T45.6 Fibrinolysis-affecting drugs	0.251	0.749	0.000
T45.4 Iron and its compounds	0.251	0.749	0.000
T45.3 Enzymes, not elsewhere classified	0.251	0.749	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.250	0.750	0.000
T37.5 Antiviral drugs	0.250	0.750	0.000
T37.4 Anthelminthics	0.250	0.750	0.000
T37.3 Other antiprotozoal drugs	0.250	0.750	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.250	0.750	0.000
T37.1 Antimycobacterial drugs	0.250	0.750	0.000
T37.0 Sulphonamides	0.250	0.750	0.000
E06.5 Other chronic thyroiditis	0.000	0.750	0.250
T36.4 Tetracyclines	0.248	0.751	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.248	0.752	0.000
E06.4 Drug-induced thyroiditis	0.000	0.754	0.246
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.754	0.246
E06.0 Acute thyroiditis	0.000	0.754	0.246
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.755	0.244
E06.1 Subacute thyroiditis	0.000	0.757	0.243
T41.5 Therapeutic gases	0.240	0.759	0.000
T41.4 Anaesthetic, unspecified	0.240	0.759	0.000
T41.3 Local anaesthetics	0.240	0.759	0.000
T41.2 Other and unspecified general anaesthetics	0.240	0.759	0.000
T41.1 Intravenous anaesthetics	0.240	0.759	0.000
T41.0 Inhaled anaesthetics	0.240	0.759	0.000
T49.9 Topical agent, unspecified	0.240	0.759	0.000
T49.8 Other topical agents	0.240	0.759	0.000
T49.7 Dental drugs, topically applied	0.240	0.759	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.240	0.759	0.000
T49.5 Ophthalmological drugs and preparations	0.240	0.759	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.240	0.759	0.000
T49.3 Emollients, demulcents and protectants	0.240	0.759	0.000
T49.2 Local astringents and local detergents	0.240	0.759	0.000
T49.1 Antipruritics	0.240	0.759	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.240	0.759	0.000
T36.9 Systemic antibiotic, unspecified	0.237	0.763	0.000
T36.8 Other systemic antibiotics	0.237	0.763	0.000
T36.7 Antifungal antibiotics, systemically used	0.237	0.763	0.000
T36.6 Rifamycins	0.237	0.763	0.000
T36.5 Aminoglycosides	0.237	0.763	0.000
T36.3 Macrolides	0.237	0.763	0.000
T36.2 Chloramphenicol group	0.237	0.763	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.237	0.763	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.232	0.767	0.000
S06 Intracranial injury	0.226	0.774	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.224	0.776	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.777	0.223
S06.8 Other intracranial injuries	0.223	0.777	0.000
L40-L45 Papulosquamous disorders	0.222	0.777	0.000
E06.3 Autoimmune thyroiditis	0.000	0.778	0.222
S06.80 Other intracranial injuries (without open intracranial wound)	0.221	0.779	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.781	0.219
E06.9 Thyroiditis, unspecified	0.000	0.781	0.218
T36.0 Penicillins	0.217	0.782	0.000
S00-S09 Injuries to the head	0.217	0.783	0.000
T47.0 Histamine H(2)-receptor antagonists	0.216	0.783	0.000
S02 Fracture of skull and facial bones	0.215	0.785	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.212	0.788	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.212	0.788	0.000
T47.7 Emetics	0.212	0.788	0.000
T47.6 Antidiarrhoeal drugs	0.212	0.788	0.000
T47.5 Digestants	0.212	0.788	0.000
T47.4 Other laxatives	0.212	0.788	0.000
T47.3 Saline and osmotic laxatives	0.212	0.788	0.000
T47.2 Stimulant laxatives	0.212	0.788	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.210	0.790	0.000
S02.4 Fracture of malar and maxillary bones	0.210	0.790	0.000
S06.2 Diffuse brain injury	0.209	0.791	0.000
T45.2 Vitamins, not elsewhere classified	0.208	0.792	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.207	0.793	0.000
S70-S79 Injuries to the hip and thigh	0.203	0.797	0.000
S02.0 Fracture of vault of skull	0.201	0.799	0.000
S06.5 Traumatic subdural haemorrhage	0.201	0.799	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.196	0.804	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.194	0.806	0.000
S02.00 Fracture of vault of skull (closed)	0.192	0.808	0.000
S70 Superficial injury of hip and thigh	0.191	0.809	0.000
K90 Intestinal malabsorption	0.001	0.810	0.189
S90-S99 Injuries to the ankle and foot	0.189	0.810	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.187	0.812	0.001
E04.8 Other specified non-toxic goitre	0.000	0.813	0.187
T43.6 Psychostimulants with abuse potential	0.186	0.814	0.000
S79 Other and unspecified injuries of hip and thigh	0.185	0.815	0.000
L41 Parapsoriasis	0.185	0.815	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.182	0.818	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.820	0.180
T43.3 Phenothiazine antipsychotics and neuroleptics	0.178	0.822	0.000
S02.1 Fracture of base of skull	0.178	0.822	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.175	0.825	0.000
S92 Fracture of foot, except ankle	0.175	0.825	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.173	0.827	0.000
S06.1 Traumatic cerebral oedema	0.172	0.828	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.170	0.830	0.000
S50-S59 Injuries to the elbow and forearm	0.169	0.831	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.168	0.832	0.000
S99 Other and unspecified injuries of ankle and foot	0.168	0.832	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.167	0.832	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.166	0.834	0.000
S79.9 Unspecified injury of hip and thigh	0.165	0.835	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.165	0.835	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.164	0.836	0.000
S06.3 Focal brain injury	0.164	0.836	0.000
L44 Other papulosquamous disorders	0.164	0.836	0.000
S92.5 Fracture of other toe	0.164	0.836	0.000
S70.0 Contusion of hip	0.163	0.837	0.000
T66-T78 Other and unspecified effects of external causes	0.163	0.837	0.000
S06.7 Intracranial injury with prolonged coma	0.162	0.837	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.162	0.838	0.000
S06.9 Intracranial injury, unspecified	0.162	0.838	0.000
T43.9 Psychotropic drug, unspecified	0.160	0.839	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.160	0.839	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.160	0.840	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.160	0.840	0.000
S08 Traumatic amputation of part of head	0.159	0.840	0.000
L41.1 Pityriasis lichenoides chronica	0.158	0.841	0.000
S06.0 Concussion	0.158	0.842	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.158	0.842	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.158	0.842	0.000
S02.7 Multiple fractures involving skull and facial bones	0.158	0.842	0.000
S10-S19 Injuries to the neck	0.158	0.842	0.000
S99.9 Unspecified injury of ankle and foot	0.157	0.843	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.156	0.844	0.000
S07 Crushing injury of head	0.155	0.844	0.000
S04 Injury of cranial nerves	0.155	0.844	0.000
S09 Other and unspecified injuries of head	0.155	0.845	0.000
K90.8 Other intestinal malabsorption	0.001	0.846	0.153
S79.8 Other specified injuries of hip and thigh	0.153	0.847	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.153	0.847	0.000
T11 Other injuries of upper limb, level unspecified	0.153	0.847	0.000
S06.4 Epidural haemorrhage	0.151	0.849	0.000
T33-T35 Frostbite	0.151	0.849	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.151	0.849	0.000
T31 Burns classified according to extent of body surface involved	0.150	0.849	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.150	0.850	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.150	0.850	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.150	0.850	0.000
K50 Crohn's disease [regional enteritis]	0.150	0.850	0.000
S51 Open wound of forearm	0.150	0.850	0.000
K50.0 Crohn's disease of small intestine	0.149	0.851	0.000
S97 Crushing injury of ankle and foot	0.149	0.851	0.000
S92.1 Fracture of talus	0.148	0.852	0.000
S92.50 Fracture of other toe (closed)	0.148	0.852	0.000
S02.5 Fracture of tooth	0.148	0.852	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.147	0.853	0.000
K50.8 Other Crohn's disease	0.147	0.853	0.000
S78 Traumatic amputation of hip and thigh	0.146	0.854	0.000
S77 Crushing injury of hip and thigh	0.146	0.854	0.000
S75 Injury of blood vessels at hip and thigh level	0.146	0.854	0.000
S74 Injury of nerves at hip and thigh level	0.146	0.854	0.000
S02.01 Fracture of vault of skull (open)	0.144	0.855	0.000
S02.10 Fracture of base of skull (closed)	0.144	0.856	0.000
K50.9 Crohn's disease, unspecified	0.144	0.856	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.144	0.856	0.000
S73.0 Dislocation of hip	0.144	0.856	0.000
S02.8 Fractures of other skull and facial bones	0.143	0.857	0.000
S50 Superficial injury of forearm	0.143	0.857	0.000
S70.1 Contusion of thigh	0.141	0.859	0.000
S92.2 Fracture of other tarsal bone(s)	0.140	0.859	0.000
S09.8 Other specified injuries of head	0.140	0.860	0.000
S92.51 Fracture of other toe (open)	0.139	0.861	0.000
S02.3 Fracture of orbital floor	0.139	0.861	0.000
S02.11 Fracture of base of skull (open)	0.139	0.861	0.000
S32 Fracture of lumbar spine and pelvis	0.138	0.862	0.000
T31.0 Burns involving less than 10% of body surface	0.137	0.863	0.000
T11.0 Superficial injury of upper limb, level unspecified	0.137	0.863	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.137	0.863	0.000
K90.3 Pancreatic steatorrhoea	0.001	0.864	0.136
K90.2 Blind loop syndrome, not elsewhere classified	0.001	0.864	0.136
K90.1 Tropical sprue	0.001	0.864	0.136
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.136	0.864	0.000
S98 Traumatic amputation of ankle and foot	0.136	0.864	0.000
S95 Injury of blood vessels at ankle and foot level	0.136	0.864	0.000
S94 Injury of nerves at ankle and foot level	0.136	0.864	0.000
S90 Superficial injury of ankle and foot	0.136	0.864	0.000
T00-T07 Injuries involving multiple body regions	0.134	0.865	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.134	0.866	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.134	0.866	0.000
T43.2 Other and unspecified antidepressants	0.133	0.867	0.000
S79.7 Multiple injuries of hip and thigh	0.133	0.867	0.000
L41.9 Parapsoriasis, unspecified	0.133	0.867	0.000
L41.8 Other parapsoriasis	0.133	0.867	0.000
L41.5 Retiform parapsoriasis	0.133	0.867	0.000
L41.4 Large plaque parapsoriasis	0.133	0.867	0.000
L41.3 Small plaque parapsoriasis	0.133	0.867	0.000
L41.2 Lymphomatoid papulosis	0.133	0.867	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.133	0.867	0.000
T66 Unspecified effects of radiation	0.133	0.867	0.000
S32.0 Fracture of lumbar vertebra	0.132	0.868	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.132	0.868	0.000
S92.3 Fracture of metatarsal bone	0.132	0.868	0.000
S55 Injury of blood vessels at forearm level	0.131	0.869	0.000
S51.7 Multiple open wounds of forearm	0.130	0.870	0.000
S36 Injury of intra-abdominal organs	0.130	0.870	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.130	0.870	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.130	0.870	0.000
S92.10 Fracture of talus (closed)	0.129	0.871	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.871	0.129
S10 Superficial injury of neck	0.129	0.871	0.000
S51.8 Open wound of other parts of forearm	0.129	0.871	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.129	0.871	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.128	0.871	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.128	0.871	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.128	0.872	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.128	0.872	0.000
S19 Other and unspecified injuries of neck	0.127	0.873	0.000
T32 Corrosions classified according to extent of body surface involved	0.126	0.874	0.000
T30 Burn and corrosion, body region unspecified	0.126	0.874	0.000
T29 Burns and corrosions of multiple body regions	0.126	0.874	0.000
S50.9 Superficial injury of forearm, unspecified	0.126	0.874	0.000
T70 Effects of air pressure and water pressure	0.126	0.874	0.000
S92.9 Fracture of foot, unspecified	0.126	0.874	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.126	0.874	0.000
L42 Pityriasis rosea	0.125	0.875	0.000
T78 Adverse effects, not elsewhere classified	0.125	0.875	0.000
T09 Other injuries of spine and trunk, level unspecified	0.125	0.875	0.000
S71 Open wound of hip and thigh	0.124	0.876	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.124	0.876	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.124	0.876	0.000
T12 Fracture of lower limb, level unspecified	0.124	0.876	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.124	0.876	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.124	0.876	0.000
T10 Fracture of upper limb, level unspecified	0.124	0.876	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.124	0.876	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.124	0.876	0.000
T08 Fracture of spine, level unspecified	0.124	0.876	0.000
S92.7 Multiple fractures of foot	0.123	0.876	0.000
T71 Asphyxiation	0.123	0.877	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.123	0.877	0.000
I10-I15 Hypertensive diseases	0.123	0.877	0.000
S37 Injury of urinary and pelvic organs	0.123	0.877	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.123	0.877	0.000
T13 Other injuries of lower limb, level unspecified	0.123	0.877	0.000
S03.2 Dislocation of tooth	0.122	0.878	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.122	0.878	0.000
L44.0 Pityriasis rubra pilaris	0.122	0.878	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.121	0.878	0.000
S02.2 Fracture of nasal bones	0.121	0.879	0.000
S58 Traumatic amputation of forearm	0.121	0.879	0.000
S57 Crushing injury of forearm	0.121	0.879	0.000
S99.7 Multiple injuries of ankle and foot	0.121	0.879	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.121	0.879	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.121	0.879	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.119	0.881	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.119	0.881	0.000
K50.1 Crohn's disease of large intestine	0.119	0.881	0.000
S08.1 Traumatic amputation of ear	0.118	0.881	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.118	0.882	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.118	0.882	0.000
L44.9 Papulosquamous disorder, unspecified	0.117	0.882	0.000
L44.8 Other specified papulosquamous disorders	0.117	0.882	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.117	0.882	0.000
L44.3 Lichen ruber moniliformis	0.117	0.882	0.000
L44.2 Lichen striatus	0.117	0.882	0.000
L44.1 Lichen nitidus	0.117	0.882	0.000
S59 Other and unspecified injuries of forearm	0.118	0.882	0.000
S11 Open wound of neck	0.118	0.882	0.000
S03.1 Dislocation of septal cartilage of nose	0.117	0.882	0.000
S73.1 Sprain and strain of hip	0.117	0.883	0.000
T74 Maltreatment syndromes	0.117	0.883	0.000
T73 Effects of other deprivation	0.117	0.883	0.000
T69 Other effects of reduced temperature	0.117	0.883	0.000
T67 Effects of heat and light	0.117	0.883	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.117	0.883	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.117	0.883	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.117	0.883	0.000
S70.8 Other superficial injuries of hip and thigh	0.117	0.883	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.116	0.883	0.000
S03.4 Sprain and strain of jaw	0.116	0.883	0.000
S03.3 Dislocation of other and unspecified parts of head	0.116	0.883	0.000
S03.0 Dislocation of jaw	0.116	0.883	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.116	0.884	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.116	0.884	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.115	0.885	0.000
S02.6 Fracture of mandible	0.115	0.885	0.000
S08.9 Traumatic amputation of unspecified part of head	0.114	0.885	0.000
S08.8 Traumatic amputation of other parts of head	0.114	0.885	0.000
S08.0 Avulsion of scalp	0.114	0.885	0.000
S09.2 Traumatic rupture of ear drum	0.114	0.886	0.000
S06.01 Concussion (with open intracranial wound)	0.114	0.886	0.000
S56 Injury of muscle and tendon at forearm level	0.114	0.886	0.000
S50.1 Contusion of other and unspecified parts of forearm	0.114	0.886	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.113	0.887	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.113	0.887	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.113	0.887	0.000
S51.0 Open wound of elbow	0.113	0.887	0.000
S17 Crushing injury of neck	0.113	0.887	0.000
S15 Injury of blood vessels at neck level	0.113	0.887	0.000
S18 Traumatic amputation at neck level	0.113	0.887	0.000
S16 Injury of muscle and tendon at neck level	0.113	0.887	0.000
T11.1 Open wound of upper limb, level unspecified	0.113	0.887	0.000
S34.1 Other injury of lumbar spinal cord	0.113	0.887	0.000
S32.5 Fracture of pubis	0.112	0.888	0.000
T14 Injury of unspecified body region	0.112	0.888	0.000
S04.9 Injury of unspecified cranial nerve	0.112	0.888	0.000
S04.8 Injury of other cranial nerves	0.112	0.888	0.000
S04.7 Injury of accessory nerve	0.112	0.888	0.000
S04.6 Injury of acoustic nerve	0.112	0.888	0.000
S04.5 Injury of facial nerve	0.112	0.888	0.000
S04.4 Injury of abducent nerve	0.112	0.888	0.000
S04.3 Injury of trigeminal nerve	0.112	0.888	0.000
S04.2 Injury of trochlear nerve	0.112	0.888	0.000
S04.1 Injury of oculomotor nerve	0.112	0.888	0.000
S04.0 Injury of optic nerve and pathways	0.112	0.888	0.000
S07.9 Crushing injury of head, part unspecified	0.112	0.888	0.000
S07.8 Crushing injury of other parts of head	0.112	0.888	0.000
S07.1 Crushing injury of skull	0.112	0.888	0.000
S07.0 Crushing injury of face	0.112	0.888	0.000
T75 Effects of other external causes	0.112	0.888	0.000
S10.9 Superficial injury of neck, part unspecified	0.111	0.889	0.000
S09.7 Multiple injuries of head	0.111	0.889	0.000
S09.1 Injury of muscle and tendon of head	0.111	0.889	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.111	0.889	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.111	0.889	0.000
T78.4 Allergy, unspecified	0.110	0.890	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.110	0.890	0.000
S76.1 Injury of quadriceps muscle and tendon	0.110	0.890	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.110	0.890	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.110	0.890	0.000
S76.0 Injury of muscle and tendon of hip	0.110	0.890	0.000
S90.8 Other superficial injuries of ankle and foot	0.110	0.890	0.000
T11.9 Unspecified injury of upper limb, level unspecified	0.110	0.890	0.000
T11.8 Other specified injuries of upper limb, level unspecified	0.110	0.890	0.000
T11.6 Traumatic amputation of upper limb, level unspecified	0.110	0.890	0.000
T11.5 Injury of unspecified muscle and tendon of upper limb, level unspecified	0.110	0.890	0.000
T11.4 Injury of unspecified blood vessel of upper limb, level unspecified	0.110	0.890	0.000
T11.3 Injury of unspecified nerve of upper limb, level unspecified	0.110	0.890	0.000
T11.2 Dislocation, strain and sprain of unspecified joint and ligament of upper limb, level unspecified	0.110	0.890	0.000
S06.00 Concussion (without open intracranial wound)	0.110	0.890	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.108	0.891	0.000
T28 Burn and corrosion of other internal organs	0.108	0.892	0.000
T27 Burn and corrosion of respiratory tract	0.108	0.892	0.000
T26 Burn and corrosion confined to eye and adnexa	0.108	0.892	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.108	0.892	0.000
T34 Frostbite with tissue necrosis	0.108	0.892	0.000
T33 Superficial frostbite	0.108	0.892	0.000
S50.8 Other superficial injuries of forearm	0.108	0.892	0.000
T31.9 Burns involving 90% or more of body surface	0.108	0.892	0.000
T31.8 Burns involving 80-89% of body surface	0.108	0.892	0.000
T31.7 Burns involving 70-79% of body surface	0.108	0.892	0.000
T31.6 Burns involving 60-69% of body surface	0.108	0.892	0.000
T31.5 Burns involving 50-59% of body surface	0.108	0.892	0.000
T31.4 Burns involving 40-49% of body surface	0.108	0.892	0.000
T31.3 Burns involving 30-39% of body surface	0.108	0.892	0.000
T31.2 Burns involving 20-29% of body surface	0.108	0.892	0.000
S54 Injury of nerves at forearm level	0.108	0.892	0.000
S97.1 Crushing injury of toe(s)	0.107	0.893	0.000
S97.0 Crushing injury of ankle	0.107	0.893	0.000
S99.8 Other specified injuries of ankle and foot	0.107	0.893	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.107	0.893	0.000
S92.11 Fracture of talus (open)	0.106	0.893	0.000
S02.51 Fracture of tooth (open)	0.106	0.894	0.000
S19.8 Other specified injuries of neck	0.105	0.895	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations