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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2596565
log Bayes Factor = 363.148
Chromosome 6   position 31,353,329  (GRCh37) Explore rs2596565 on Ensembl!
Variant rs2596565 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
J45 Asthma
1.000 0.000 0.000
K75 Other inflammatory liver diseases
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E27.1 Primary adrenocortical insufficiency
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
D69 Purpura and other haemorrhagic conditions
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
D80-D89 Certain disorders involving the immune mechanism
1.000 0.000 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
1.000 0.000 0.000
E27 Other disorders of adrenal gland
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
K75.4 Autoimmune hepatitis
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
B35-B49 Mycoses
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
I73 Other peripheral vascular diseases
0.999 0.001 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.999 0.001 0.000
E14.3 With ophthalmic complications
0.999 0.001 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.999 0.001 0.000
B37 Candidiasis
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
N00-N08 Glomerular diseases
0.999 0.001 0.000
D69.6 Thrombocytopenia, unspecified
0.999 0.001 0.000
J33 Nasal polyp
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
D50-D53 Nutritional anaemias
0.999 0.001 0.000
J33.0 Polyp of nasal cavity
0.998 0.002 0.000
D86 Sarcoidosis
0.998 0.002 0.000
C83.3 Large cell (diffuse)
0.998 0.002 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.998 0.002 0.000
E89.0 Postprocedural hypothyroidism
0.998 0.002 0.000
R30-R39 Symptoms and signs involving the urinary system
0.000 0.002 0.998
J44 Other chronic obstructive pulmonary disease
0.997 0.003 0.000
C85.1 B-cell lymphoma, unspecified
0.997 0.003 0.000
J33.9 Nasal polyp, unspecified
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.997 0.003 0.000
D50 Iron deficiency anaemia
0.996 0.004 0.000
D86.9 Sarcoidosis, unspecified
0.995 0.005 0.000
M06 Other rheumatoid arthritis
0.995 0.005 0.000
M06.9 Rheumatoid arthritis, unspecified
0.994 0.006 0.000
N17-N19 Renal failure
0.994 0.006 0.000
E11.3 With ophthalmic complications
0.994 0.006 0.000
I73.0 Raynaud's syndrome
0.994 0.006 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.994 0.006 0.000
B37.9 Candidiasis, unspecified
0.994 0.006 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.993 0.007 0.000
R30 Pain associated with micturition
0.000 0.007 0.993
E10.2 With renal complications
0.993 0.007 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.993 0.007 0.000
N04 Nephrotic syndrome
0.993 0.007 0.000
K50-K52 Noninfective enteritis and colitis
0.980 0.007 0.012
M20.1 Hallux valgus (acquired)
0.000 0.007 0.993
D50.9 Iron deficiency anaemia, unspecified
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
I60-I69 Cerebrovascular diseases
0.992 0.008 0.000
R30.0 Dysuria
0.000 0.009 0.991
I74 Arterial embolism and thrombosis
0.991 0.009 0.000
N18 Chronic renal failure
0.991 0.009 0.000
J30-J39 Other diseases of upper respiratory tract
0.990 0.010 0.000
I63 Cerebral infarction
0.990 0.010 0.000
I77 Other disorders of arteries and arterioles
0.990 0.010 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.989 0.011 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.989 0.011 0.000
E50-E64 Other nutritional deficiencies
0.988 0.012 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.988 0.012 0.000
D61 Other aplastic anaemias
0.988 0.012 0.000
K52 Other non-infective gastro-enteritis and colitis
0.981 0.013 0.006
A30-A49 Other bacterial diseases
0.987 0.013 0.000
I73.9 Peripheral vascular disease, unspecified
0.985 0.015 0.000
D70 Agranulocytosis
0.984 0.016 0.000
K73 Chronic hepatitis, not elsewhere classified
0.984 0.016 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.984 0.016 0.000
N04.9 Unspecified
0.984 0.016 0.000
M20 Acquired deformities of fingers and toes
0.000 0.016 0.983
L97 Ulcer of lower limb, not elsewhere classified
0.983 0.017 0.000
E14.9 Without complications
0.983 0.017 0.000
M15-M19 Arthrosis
0.983 0.017 0.000
W00-W19 Falls
0.981 0.019 0.000
W19 Unspecified fall
0.981 0.019 0.000
A41 Other septicaemia
0.980 0.020 0.000
G56 Mononeuropathies of upper limb
0.980 0.020 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.021 0.979
L50-L54 Urticaria and erythema
0.979 0.021 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.979 0.021 0.000
G56.0 Carpal tunnel syndrome
0.978 0.022 0.000
K90.9 Intestinal malabsorption, unspecified
0.978 0.022 0.000
R63.4 Abnormal weight loss
0.977 0.023 0.000
A41.9 Septicaemia, unspecified
0.976 0.024 0.000
M34 Systemic sclerosis
0.976 0.024 0.000
I77.1 Stricture of artery
0.976 0.024 0.000
M35.3 Polymyalgia rheumatica
0.975 0.025 0.000
D61.9 Aplastic anaemia, unspecified
0.975 0.025 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.975 0.025 0.000
C91 Lymphoid leukaemia
0.975 0.025 0.000
W19.9 Unspecified place
0.975 0.025 0.000
E10.4 With neurological complications
0.974 0.026 0.000
N40 Hyperplasia of prostate
0.000 0.030 0.970
N05 Unspecified nephritic syndrome
0.969 0.031 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.968 0.032 0.000
Chapter II Neoplasms
0.967 0.033 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.966 0.034 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.964 0.036 0.000
R35 Polyuria
0.000 0.038 0.962
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.961 0.039 0.000
M18 Arthrosis of first carpometacarpal joint
0.961 0.039 0.000
L10-L14 Bullous disorders
0.960 0.040 0.000
E06 Thyroiditis
0.959 0.041 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.959 0.041 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.958 0.042 0.000
R39 Other symptoms and signs involving the urinary system
0.000 0.043 0.957
M24 Other specific joint derangements
0.955 0.045 0.000
G51 Facial nerve disorders
0.955 0.045 0.000
C81 Hodgkin's disease
0.953 0.047 0.000
H06.2 Dysthyroid exophthalmos
0.952 0.048 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.952 0.048 0.000
K72 Hepatic failure, not elsewhere classified
0.952 0.048 0.000
J46 Status asthmaticus
0.951 0.049 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.000 0.049 0.951
B37.0 Candidal stomatitis
0.950 0.050 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.950 0.050 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.949 0.051 0.000
B37.8 Candidiasis of other sites
0.948 0.052 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.946 0.054 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.945 0.055 0.000
N18.9 Chronic renal failure, unspecified
0.943 0.057 0.000
E53 Deficiency of other B group vitamins
0.942 0.058 0.000
M17 Gonarthrosis [arthrosis of knee]
0.942 0.058 0.000
E11.9 Without complications
0.939 0.061 0.000
M60-M63 Disorders of muscles
0.939 0.061 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.938 0.062 0.000
C91.1 Chronic lymphocytic leukaemia
0.937 0.063 0.000
J84 Other interstitial pulmonary diseases
0.936 0.064 0.000
L94 Other localised connective tissue disorders
0.936 0.064 0.000
E11.1 With ketoacidosis
0.935 0.065 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.935 0.065 0.000
K75.8 Other specified inflammatory liver diseases
0.934 0.066 0.000
C15-C26 Malignant neoplasms of digestive organs
0.934 0.066 0.000
A63.0 Anogenital (venereal) warts
0.932 0.068 0.000
L13 Other bullous disorders
0.932 0.068 0.000
M21 Other acquired deformities of limbs
0.931 0.069 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.931 0.069 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.927 0.073 0.000
D80 Immunodeficiency with predominantly antibody defects
0.926 0.074 0.000
M17.1 Other primary gonarthrosis
0.925 0.075 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.925 0.075 0.000
E06.3 Autoimmune thyroiditis
0.925 0.075 0.000
L52 Erythema nodosum
0.924 0.076 0.000
N18.3 Chronic kidney disease, stage 3
0.924 0.076 0.000
H34 Retinal vascular occlusions
0.924 0.076 0.000
E55 Vitamin D deficiency
0.924 0.076 0.000
I77.6 Arteritis, unspecified
0.923 0.077 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.922 0.078 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.919 0.081 0.000
N05.2 Diffuse membranous glomerulonephritis
0.918 0.082 0.000
M86-M90 Other osteopathies
0.917 0.083 0.000
G30-G32 Other degenerative diseases of the nervous system
0.915 0.085 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.914 0.086 0.000
N18.0 End-stage renal disease
0.914 0.086 0.000
H05 Disorders of orbit
0.913 0.086 0.000
E11.5 With peripheral circulatory complications
0.913 0.087 0.000
I63.8 Other cerebral infarction
0.912 0.088 0.000
M32 Systemic lupus erythematosus
0.912 0.088 0.000
L13.0 Dermatitis herpetiformis
0.911 0.089 0.000
C16 Malignant neoplasm of stomach
0.908 0.092 0.000
B44 Aspergillosis
0.904 0.096 0.000
E53.8 Deficiency of other specified B group vitamins
0.904 0.096 0.000
G51.9 Disorder of facial nerve, unspecified
0.903 0.097 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.903 0.097 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.902 0.097 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.902 0.098 0.000
L20-L30 Dermatitis and eczema
0.896 0.104 0.000
N10-N16 Renal tubulo-interstitial diseases
0.895 0.105 0.000
E83.1 Disorders of iron metabolism
0.000 0.106 0.894
K73.9 Chronic hepatitis, unspecified
0.894 0.106 0.000
D69.4 Other primary thrombocytopenia
0.894 0.106 0.000
H25-H28 Disorders of lens
0.892 0.108 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.891 0.109 0.000
C83.0 Small cell (diffuse)
0.890 0.110 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.890 0.110 0.000
B25-B34 Other viral diseases
0.888 0.112 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.887 0.113 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.886 0.114 0.000
K74 Fibrosis and cirrhosis of liver
0.885 0.115 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.883 0.117 0.000
D55-D59 Haemolytic anaemias
0.883 0.117 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.881 0.119 0.000
M15 Polyarthrosis
0.880 0.120 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.880 0.120 0.000
M10 Gout
0.879 0.121 0.000
D50.8 Other iron deficiency anaemias
0.878 0.122 0.000
E55.9 Vitamin D deficiency, unspecified
0.878 0.122 0.000
H30 Chorioretinal inflammation
0.878 0.122 0.000
M86 Osteomyelitis
0.873 0.127 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.873 0.127 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.873 0.127 0.000
L92.0 Granuloma annulare
0.872 0.128 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.871 0.129 0.000
H43-H45 Disorders of vitreous body and globe
0.871 0.129 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.869 0.131 0.000
E24 Cushing's syndrome
0.869 0.131 0.000
H04 Disorders of lachrymal system
0.869 0.131 0.000
D51 Vitamin B12 deficiency anaemia
0.865 0.135 0.000
Y42.7 Androgens and anabolic congeners
0.864 0.136 0.000
G51.0 Bell's palsy
0.863 0.137 0.000
K72.0 Acute and subacute hepatic failure
0.863 0.137 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.137 0.863
M35.7 Hypermobility syndrome
0.863 0.137 0.000
D69.2 Other nonthrombocytopenic purpura
0.863 0.137 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.860 0.140 0.000
M62 Other disorders of muscle
0.859 0.141 0.000
C88 Malignant immunoproliferative diseases
0.859 0.141 0.000
H34.8 Other retinal vascular occlusions
0.858 0.142 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.857 0.143 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.857 0.143 0.000
C16.9 Stomach, unspecified
0.854 0.146 0.000
V40-V49 Car occupant injured in transport accident
0.853 0.147 0.000
W19.2 School, other institution and public administrative area
0.852 0.148 0.000
E10.8 With unspecified complications
0.850 0.150 0.000
I74.8 Embolism and thrombosis of other arteries
0.850 0.150 0.000
M34.1 CR(E)ST syndrome
0.849 0.151 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.849 0.151 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.849 0.151 0.000
L50 Urticaria
0.848 0.152 0.000
C81.1 Nodular sclerosis
0.848 0.152 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.848 0.152 0.000
N11 Chronic tubulo-interstitial nephritis
0.848 0.152 0.000
B15-B19 Viral hepatitis
0.848 0.152 0.000
M21.0 Valgus deformity, not elsewhere classified
0.848 0.152 0.000
M34.9 Systemic sclerosis, unspecified
0.848 0.152 0.000
E14.8 With unspecified complications
0.847 0.153 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.847 0.153 0.000
D86.0 Sarcoidosis of lung
0.847 0.153 0.000
K72.9 Hepatic failure, unspecified
0.846 0.154 0.000
C81.9 Hodgkin's disease, unspecified
0.846 0.154 0.000
C04 Malignant neoplasm of floor of mouth
0.846 0.154 0.000
B25 Cytomegaloviral disease
0.845 0.155 0.000
W19.3 Sports and athletics area
0.844 0.156 0.000
E14.2 Withrenal complications
0.843 0.157 0.000
Y52 Agents primarily affecting the cardiovascular system
0.842 0.158 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.841 0.159 0.000
H26 Other cataract
0.841 0.159 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.841 0.159 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.841 0.159 0.000
N17 Acute renal failure
0.840 0.160 0.000
V20-V29 Motorcycle rider injured in transport accident
0.840 0.160 0.000
N25-N29 Other disorders of kidney and ureter
0.839 0.161 0.000
E10.5 With peripheral circulatory complications
0.835 0.165 0.000
H05.2 Exophthalmic conditions
0.835 0.165 0.000
J33.8 Other polyp of sinus
0.834 0.166 0.000
M34.8 Other forms of systemic sclerosis
0.833 0.167 0.000
K74.6 Other and unspecified cirrhosis of liver
0.833 0.167 0.000
B02 Zoster [herpes zoster]
0.832 0.168 0.000
H04.1 Other disorders of lachrymal gland
0.832 0.168 0.000
L53 Other erythematous conditions
0.832 0.168 0.000
E10.7 With multiple complications
0.831 0.169 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.830 0.170 0.000
E14.1 With ketoacidosis
0.830 0.170 0.000
J37 Chronic laryngitis and laryngotracheitis
0.829 0.171 0.000
D69.5 Secondary thrombocytopenia
0.828 0.172 0.000
M21.8 Other specified acquired deformities of limbs
0.828 0.172 0.000
E03.8 Other specified hypothyroidism
0.828 0.172 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.828 0.172 0.000
L28 Lichen simplex chronicus and prurigo
0.827 0.173 0.000
C92 Myeloid leukaemia
0.826 0.174 0.000
Chapter VIII Diseases of the ear and mastoid process
0.826 0.174 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.826 0.174 0.000
E10.0 With coma
0.825 0.175 0.000
M34.0 Progressive systemic sclerosis
0.824 0.175 0.000
C84.5 Other and unspecified T-cell lymphomas
0.823 0.177 0.000
D50.1 Sideropenic dysphagia
0.822 0.178 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.821 0.179 0.000
H26.9 Cataract, unspecified
0.821 0.179 0.000
I62 Other nontraumatic intracranial haemorrhage
0.821 0.179 0.000
E78.2 Mixed hyperlipidaemia
0.820 0.180 0.000
E88 Other metabolic disorders
0.820 0.180 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.819 0.181 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.818 0.182 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.818 0.182 0.000
C20 Malignant neoplasm of rectum
0.814 0.186 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.814 0.186 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.814 0.186 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.813 0.187 0.000
D69.9 Haemorrhagic condition, unspecified
0.813 0.187 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.813 0.187 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.812 0.188 0.000
M24.1 Other articular cartilage disorders
0.812 0.188 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.812 0.188 0.000
L93 Lupus erythematosus
0.812 0.188 0.000
N13 Obstructive and reflux uropathy
0.811 0.189 0.000
G35 Multiple sclerosis
0.810 0.190 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.809 0.191 0.000
D86.3 Sarcoidosis of skin
0.808 0.192 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.808 0.192 0.000
I71 Aortic aneurysm and dissection
0.807 0.193 0.000
C83.7 Burkitt's tumour
0.806 0.194 0.000
G31.8 Other specified degenerative diseases of nervous system
0.804 0.196 0.000
B25.9 Cytomegaloviral disease, unspecified
0.803 0.197 0.000
N04.2 Diffuse membranous glomerulonephritis
0.802 0.198 0.000
M20.3 Other deformity of hallux (acquired)
0.000 0.200 0.800
D80.1 Nonfamilial hypogammaglobulinaemia
0.799 0.201 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.799 0.201 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.799 0.201 0.000
H43 Disorders of vitreous body
0.799 0.201 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.799 0.201 0.000
D83 Common variable immunodeficiency
0.799 0.201 0.000
M62.8 Other specified disorders of muscle
0.798 0.202 0.000
N18.4 Chronic kidney disease, stage 4
0.797 0.203 0.000
E31 Polyglandular dysfunction
0.797 0.203 0.000
B00 Herpesviral [herpes simplex] infections
0.797 0.203 0.000
E14.6 With other specified complications
0.796 0.204 0.000
M24.5 Contracture of joint
0.796 0.204 0.000
L94.0 Localised scleroderma [morphea]
0.796 0.204 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.795 0.205 0.000
V01-V09 Pedestrian injured in transport accident
0.795 0.205 0.000
M24.2 Disorder of ligament
0.795 0.205 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.794 0.206 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.794 0.206 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.793 0.207 0.000
M60 Myositis
0.792 0.208 0.000
D61.1 Drug-induced aplastic anaemia
0.792 0.208 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.792 0.208 0.000
D53 Other nutritional anaemias
0.792 0.208 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.791 0.209 0.000
H30.9 Chorioretinal inflammation, unspecified
0.790 0.210 0.000
E07 Other disorders of thyroid
0.790 0.210 0.000
E51 Thiamine deficiency
0.790 0.210 0.000
C91.9 Lymphoid leukaemia, unspecified
0.789 0.211 0.000
Y42.2 Antithyroid drugs
0.787 0.212 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.787 0.213 0.000
H00.1 Chalazion
0.000 0.213 0.786
D59 Acquired haemolytic anaemia
0.786 0.214 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.784 0.215 0.000
B44.9 Aspergillosis, unspecified
0.784 0.216 0.000
B37.7 Candidal septicaemia
0.784 0.216 0.000
G70-G73 Diseases of myoneural junction and muscle
0.784 0.216 0.000
M31 Other necrotising vasculopathies
0.784 0.216 0.000
N05.1 Focal and segmental glomerular lesions
0.783 0.217 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.783 0.217 0.000
G52 Disorders of other cranial nerves
0.782 0.218 0.000
M86.9 Osteomyelitis, unspecified
0.782 0.218 0.000
E10.6 With other specified complications
0.780 0.220 0.000
M33 Dermatopolymyositis
0.779 0.221 0.000
W19.1 Residential institution
0.779 0.221 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.778 0.222 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.778 0.222 0.000
H43.1 Vitreous haemorrhage
0.776 0.224 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.776 0.224 0.000
C07 Malignant neoplasm of parotid gland
0.776 0.224 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.775 0.225 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.775 0.225 0.000
I10-I15 Hypertensive diseases
0.775 0.225 0.000
N18.8 Other chronic renal failure
0.775 0.225 0.000
M06.4 Inflammatory polyarthropathy
0.774 0.226 0.000
N04.1 Focal and segmental glomerular lesions
0.774 0.226 0.000
L94.2 Calcinosis cutis
0.773 0.227 0.000
C83.1 Small cleaved cell (diffuse)
0.772 0.228 0.000
K76 Other diseases of liver
0.772 0.228 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.772 0.228 0.000
X10-X19 Contact with heat and hot substances
0.772 0.228 0.000
H60-H62 Diseases of external ear
0.771 0.229 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.771 0.229 0.000
N18.1 Chronic kidney disease, stage 1
0.771 0.229 0.000
W19.6 Industrial and construction area
0.770 0.230 0.000
A48 Other bacterial diseases, not elsewhere classified
0.770 0.230 0.000
M89 Other disorders of bone
0.769 0.231 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.769 0.231 0.000
L94.9 Localised connective tissue disorder, unspecified
0.768 0.232 0.000
G62 Other polyneuropathies
0.767 0.233 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.236 0.764
C84.8 Cutaneous T-cell lymphoma, unspecified
0.764 0.236 0.000
E78.4 Other hyperlipidaemia
0.764 0.236 0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.763 0.237 0.000
D86.1 Sarcoidosis of lymph nodes
0.763 0.237 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.763 0.237 0.000
M10.9 Gout, unspecified
0.762 0.238 0.000
W05 Fall involving wheelchair
0.761 0.238 0.000
K90.8 Other intestinal malabsorption
0.761 0.239 0.000
I27 Other pulmonary heart diseases
0.761 0.239 0.000
G50 Disorders of trigeminal nerve
0.760 0.240 0.000
C25 Malignant neoplasm of pancreas
0.760 0.240 0.000
J90-J94 Other diseases of pleura
0.760 0.240 0.000
E74 Other disorders of carbohydrate metabolism
0.760 0.240 0.000
W20-W49 Exposure to inanimate mechanical forces
0.760 0.240 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.759 0.241 0.000
E11.8 With unspecified complications
0.759 0.241 0.000
I60 Subarachnoid haemorrhage
0.759 0.241 0.000
B44.1 Other pulmonary aspergillosis
0.759 0.241 0.000
E14.5 With peripheral circulatory complications
0.758 0.242 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.757 0.242 0.000
G62.9 Polyneuropathy, unspecified
0.758 0.242 0.000
L28.0 Lichen simplex chronicus
0.755 0.245 0.000
C10 Malignant neoplasm of oropharynx
0.754 0.246 0.000
E11.6 With other specified complications
0.753 0.247 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.753 0.247 0.000
E78.5 Hyperlipidaemia, unspecified
0.753 0.247 0.000
B36 Other superficial mycoses
0.752 0.247 0.000
E73 Lactose intolerance
0.752 0.248 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.752 0.248 0.000
M35.1 Other overlap syndromes
0.752 0.248 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.752 0.248 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.751 0.249 0.000
J95-J99 Other diseases of the respiratory system
0.751 0.249 0.000
W13 Fall from, out of or through building or structure
0.750 0.250 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.750 0.250 0.000
E78.8 Other disorders of lipoprotein metabolism
0.749 0.251 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.749 0.251 0.000
J41 Simple and mucopurulent chronic bronchitis
0.749 0.251 0.000
C91.0 Acute lymphoblastic leukaemia
0.748 0.252 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.747 0.253 0.000
E24.2 Drug-induced Cushing's syndrome
0.747 0.253 0.000
D84 Other immunodeficiencies
0.747 0.253 0.000
L80 Vitiligo
0.747 0.253 0.000
E22 Hyperfunction of pituitary gland
0.747 0.253 0.000
L83 Acanthosis nigricans
0.747 0.253 0.000
H34.2 Other retinal artery occlusions
0.746 0.254 0.000
K75.9 Inflammatory liver disease, unspecified
0.745 0.255 0.000
C16.8 Overlapping lesion of stomach
0.745 0.255 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.745 0.255 0.000
W50-W64 Exposure to animate mechanical forces
0.745 0.255 0.000
D64.8 Other specified anaemias
0.744 0.256 0.000
I63.9 Cerebral infarction, unspecified
0.744 0.256 0.000
C84.0 Mycosis fungoides
0.744 0.256 0.000
G56.1 Other lesions of median nerve
0.744 0.256 0.000
V90-V94 Water transport accidents
0.744 0.256 0.000
N05.9 Unspecified
0.744 0.256 0.000
B02.9 Zoster without complication
0.743 0.257 0.000
A40 Streptococcal septicaemia
0.743 0.257 0.000
C23 Malignant neoplasm of gallbladder
0.743 0.257 0.000
E78.6 Lipoprotein deficiency
0.743 0.257 0.000
M12 Other specific arthropathies
0.743 0.257 0.000
H27 Other disorders of lens
0.742 0.258 0.000
E20 Hypoparathyroidism
0.742 0.258 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.741 0.259 0.000
M17.0 Primary gonarthrosis, bilateral
0.741 0.259 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.741 0.259 0.000
M24.6 Ankylosis of joint
0.741 0.259 0.000
W14 Fall from tree
0.741 0.259 0.000
J45.0 Predominantly allergic asthma
0.740 0.260 0.000
B37.2 Candidiasis of skin and nail
0.740 0.260 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.739 0.261 0.000
L94.8 Other specified localised connective tissue disorders
0.739 0.261 0.000
M07 Psoriatic and enteropathic arthropathies
0.739 0.261 0.000
L50.1 Idiopathic urticaria
0.739 0.261 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.737 0.262 0.000
C02.9 Tongue, unspecified
0.737 0.263 0.000
I77.2 Rupture of artery
0.736 0.263 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.736 0.264 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.736 0.264 0.000
D62 Acute posthaemorrhagic anaemia
0.735 0.265 0.000
C04.0 Anterior floor of mouth
0.734 0.266 0.000
B01 Varicella [chickenpox]
0.734 0.266 0.000
C91.4 Hairy-cell leukaemia
0.733 0.267 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.733 0.267 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.732 0.268 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.732 0.268 0.000
D68 Other coagulation defects
0.731 0.269 0.000
E06.9 Thyroiditis, unspecified
0.730 0.270 0.000
C16.3 Pyloric antrum
0.729 0.271 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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