TreeWAS – Variant ID: rs2596574

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	1.000
E03 Other hypothyroidism	0.000	1.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	1.000
# Top node	0.001	0.999
L40-L45 Papulosquamous disorders	0.003	0.997
L40 Psoriasis	0.003	0.997
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.005	0.995
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.006	0.994
M06.9 Rheumatoid arthritis, unspecified	0.008	0.992
E65-E68 Obesity and other hyperalimentation	0.008	0.992
M06 Other rheumatoid arthritis	0.010	0.990
L57 Skin changes due to chronic exposure to nonionising radiation	0.010	0.990
M05-M14 Inflammatory polyarthropathies	0.011	0.989
L40.5 Arthropathic psoriasis	0.013	0.987
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.013	0.987
E66 Obesity	0.014	0.986
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.014	0.986
L40.9 Psoriasis, unspecified	0.015	0.985
E66.8 Other obesity	0.015	0.985
D50-D53 Nutritional anaemias	0.016	0.984
L57.0 Actinic keratosis	0.018	0.982
D50 Iron deficiency anaemia	0.019	0.981
Chapter I Certain infectious and parasitic diseases	0.021	0.979
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.021	0.979
D50.9 Iron deficiency anaemia, unspecified	0.023	0.977
L00-L08 Infections of the skin and subcutaneous tissue	0.025	0.975
E70-E90 Metabolic disorders	0.027	0.973
B35-B49 Mycoses	0.028	0.972
B37 Candidiasis	0.030	0.970
B37.8 Candidiasis of other sites	0.032	0.968
L02 Cutaneous abscess, furuncle and carbuncle	0.040	0.960
Chapter VIII Diseases of the ear and mastoid process	0.043	0.957
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.050	0.950
B25-B34 Other viral diseases	0.068	0.932
H65-H75 Diseases of middle ear and mastoid	0.071	0.929
L20-L30 Dermatitis and eczema	0.075	0.924
H72 Perforation of tympanic membrane	0.085	0.915
B37.0 Candidal stomatitis	0.090	0.910
E06 Thyroiditis	0.092	0.908
H72.9 Perforation of tympanic membrane, unspecified	0.094	0.906
M07 Psoriatic and enteropathic arthropathies	0.094	0.906
M45-M49 Spondylopathies	0.099	0.901
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.101	0.899
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.103	0.897
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.107	0.893
B34 Viral infection of unspecified site	0.108	0.892
M45 Ankylosing spondylitis	0.111	0.889
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.111	0.889
E10-E14 Diabetes mellitus	0.115	0.885
M45.X9 Ankylosing spondylitis (Site unspecified)	0.126	0.874
E87 Other disorders of fluid, electrolyte and acid-base balance	0.128	0.872
E05 Thyrotoxicosis [hyperthyroidism]	0.142	0.858
Chapter V Mental and behavioural disorders	0.142	0.858
E10 Insulin-dependent diabetes mellitus	0.146	0.854
M05 Seropositive rheumatoid arthritis	0.149	0.851
E89.0 Postprocedural hypothyroidism	0.150	0.850
B34.9 Viral infection, unspecified	0.151	0.849
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.152	0.848
M07.3 Other psoriatic arthropathies	0.154	0.846
H65 Nonsuppurative otitis media	0.155	0.845
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.156	0.844
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.164	0.836
E86 Volume depletion	0.166	0.834
L29 Pruritus	0.166	0.834
L08 Other local infections of skin and subcutaneous tissue	0.167	0.833
E06.3 Autoimmune thyroiditis	0.168	0.832
H80-H83 Diseases of inner ear	0.170	0.830
D80-D89 Certain disorders involving the immune mechanism	0.171	0.829
D68 Other coagulation defects	0.178	0.822
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.178	0.822
M35 Other systemic involvement of connective tissue	0.180	0.820
M95.0 Acquired deformity of nose	0.180	0.820
M35.3 Polymyalgia rheumatica	0.182	0.818
M20-M25 Other joint disorders	0.182	0.818
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.185	0.815
B20-B24 Human immunodeficiency virus [HIV] disease	0.185	0.814
M06.0 Seronegative rheumatoid arthritis	0.189	0.811
E20-E35 Disorders of other endocrine glands	0.194	0.806
E87.1 Hypo-osmolality and hyponatraemia	0.194	0.806
L29.0 Pruritus ani	0.209	0.791
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.210	0.790
B35 Dermatophytosis	0.210	0.790
B99-B99 Other infectious diseases	0.227	0.773
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.228	0.772
E27 Other disorders of adrenal gland	0.229	0.771
M07.30 Other psoriatic arthropathies (Multiple sites)	0.232	0.768
E87.2 Acidosis	0.233	0.767
E05.0 Thyrotoxicosis with diffuse goitre	0.235	0.765
E73 Lactose intolerance	0.236	0.764
D86 Sarcoidosis	0.237	0.763
D55-D59 Haemolytic anaemias	0.239	0.761
H72.0 Central perforation of tympanic membrane	0.242	0.758
E88 Other metabolic disorders	0.242	0.758
A50-A64 Infections with a predominantly sexual mode of transmission	0.247	0.753
M05.9 Seropositive rheumatoid arthritis, unspecified	0.247	0.752
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.248	0.752
M00-M03 Infectious arthropathies	0.248	0.752
E66.0 Obesity due to excess calories	0.248	0.752
L30 Other dermatitis	0.252	0.748
E10.3 With ophthalmic complications	0.252	0.748
E27.1 Primary adrenocortical insufficiency	0.254	0.746
L56 Other acute skin changes due to ultraviolet radiation	0.257	0.743
E10.9 Without complications	0.259	0.741
H65.9 Nonsuppurative otitis media, unspecified	0.259	0.741
B34.8 Other viral infections of unspecified site	0.263	0.737
H80 Otosclerosis	0.264	0.736
L27 Dermatitis due to substances taken internally	0.265	0.735
M14 Arthropathies in other diseases classified elsewhere	0.269	0.731
Chapter XXII Codes for special purposes	0.270	0.730
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.273	0.727
L05 Pilonidal cyst	0.274	0.726
E80 Disorders of porphyrin and bilirubin metabolism	0.277	0.723
E65 Localised adiposity	0.280	0.720
M35.0 Sicca syndrome [Sjogren]	0.280	0.720
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.280	0.720
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.283	0.717
E03.5 Myxoedema coma	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.283	0.717
Chapter XVI Certain conditions originating in the perinatal period	0.283	0.717
L44 Other papulosquamous disorders	0.285	0.715
L41 Parapsoriasis	0.285	0.715
L45 Papulosquamous disorders in diseases classified elsewhere	0.285	0.715
M07.39 Other psoriatic arthropathies (Site unspecified)	0.285	0.715
L40.8 Other psoriasis	0.285	0.714
L40.4 Guttate psoriasis	0.285	0.714
L40.3 Pustulosis palmaris et plantaris	0.285	0.714
L40.2 Acrodermatitis continua	0.285	0.714
L40.1 Generalised pustular psoriasis	0.285	0.714
D68.5 Primary Thrombophilia	0.287	0.713
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.287	0.713
L58 Radiodermatitis	0.287	0.713
L55 Sunburn	0.287	0.713
M06.98 Rheumatoid arthritis, unspecified (Other)	0.289	0.711
E67 Other hyperalimentation	0.289	0.711
E68 Sequelae of hyperalimentation	0.289	0.711
F00-F09 Organic, including symptomatic, mental disorders	0.289	0.711
M06.8 Other specified rheumatoid arthritis	0.290	0.710
M06.2 Rheumatoid bursitis	0.290	0.710
M06.1 Adult-onset Still's disease	0.290	0.710
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.290	0.710
L57.5 Actinic granuloma	0.290	0.710
L57.3 Poikiloderma of Civatte	0.290	0.710
L57.2 Cutis rhomboidalis nuchae	0.290	0.710
L57.1 Actinic reticuloid	0.290	0.710
M12 Other specific arthropathies	0.291	0.709
M09 Juvenile arthritis in diseases classified elsewhere	0.291	0.709
M08 Juvenile arthritis	0.291	0.709
E66.1 Drug-induced obesity	0.293	0.707
E74 Other disorders of carbohydrate metabolism	0.293	0.707
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.296	0.704
B25 Cytomegaloviral disease	0.296	0.704
D50.1 Sideropenic dysphagia	0.297	0.703
E10.1 With ketoacidosis	0.297	0.703
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.298	0.702
A75-A79 Rickettsioses	0.298	0.702
A70-A74 Other diseases caused by chlamydiae	0.298	0.702
A65-A69 Other spirochaetal diseases	0.298	0.702
A20-A28 Certain zoonotic bacterial diseases	0.298	0.702
M34 Systemic sclerosis	0.299	0.701
E50-E64 Other nutritional deficiencies	0.299	0.700
L04 Acute lymphadenitis	0.301	0.699
L01 Impetigo	0.301	0.699
L00 Staphylococcal scalded skin syndrome	0.301	0.699
H73 Other disorders of tympanic membrane	0.302	0.698
E84 Cystic fibrosis	0.302	0.698
E79 Disorders of purine and pyrimidine metabolism	0.302	0.698
E77 Disorders of glycoprotein metabolism	0.302	0.698
E76 Disorders of glycosaminoglycan metabolism	0.302	0.698
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.302	0.698
E72 Other disorders of amino-acid metabolism	0.302	0.698
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.302	0.698
E70 Disorders of aromatic amino-acid metabolism	0.302	0.698
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.302	0.698
B48 Other mycoses, not elsewhere classified	0.303	0.697
B47 Mycetoma	0.303	0.697
B46 Zygomycosis	0.303	0.697
B45 Cryptococcosis	0.303	0.697
B43 Chromomycosis and phaeomycotic abscess	0.303	0.697
B42 Sporotrichosis	0.303	0.697
B41 Paracoccidioidomycosis	0.303	0.697
B40 Blastomycosis	0.303	0.697
B39 Histoplasmosis	0.303	0.697
B38 Coccidioidomycosis	0.303	0.697
B36 Other superficial mycoses	0.303	0.697
B24 Unspecified human immunodeficiency virus [HIV] disease	0.304	0.696
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.304	0.696
B37.7 Candidal septicaemia	0.304	0.695
B37.6 Candidal endocarditis	0.304	0.695
B37.5 Candidal meningitis	0.304	0.695
D86.9 Sarcoidosis, unspecified	0.305	0.695
F30-F39 Mood [affective] disorders	0.305	0.695
D68.9 Coagulation defect, unspecified	0.307	0.693
F40-F48 Neurotic, stress-related and somatoform disorders	0.310	0.690
E06.9 Thyroiditis, unspecified	0.312	0.688
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.312	0.688
F80-F89 Disorders of psychological development	0.313	0.687
A15-A19 Tuberculosis	0.316	0.684
L57.4 Cutis laxa senilis	0.319	0.681
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.321	0.679
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.321	0.679
E14 Unspecified diabetes mellitus	0.322	0.678
L10-L14 Bullous disorders	0.322	0.677
H60-H62 Diseases of external ear	0.324	0.676
M46 Other inflammatory spondylopathies	0.325	0.674
B50-B64 Protozoal diseases	0.326	0.674
L28 Lichen simplex chronicus and prurigo	0.328	0.671
M35.7 Hypermobility syndrome	0.329	0.671
F60-F69 Disorders of adult personality and behaviour	0.329	0.671
H80.9 Otosclerosis, unspecified	0.330	0.670
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.331	0.669
E40-E46 Malnutrition	0.331	0.668
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.332	0.668
B33 Other viral diseases, not elsewhere classified	0.332	0.668
B30 Viral conjunctivitis	0.332	0.668
B27 Infectious mononucleosis	0.332	0.668
B26 Mumps	0.332	0.668
H83 Other diseases of inner ear	0.333	0.667
E10.2 With renal complications	0.334	0.666
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.334	0.666
H68 Eustachian salpingitis and obstruction	0.334	0.666
H67 Otitis media in diseases classified elsewhere	0.334	0.666
H65.2 Chronic serous otitis media	0.336	0.664
H70 Mastoiditis and related conditions	0.336	0.664
M11 Other crystal arthropathies	0.336	0.664
E10.5 With peripheral circulatory complications	0.336	0.664
E10.4 With neurological complications	0.336	0.663
L24 Irritant contact dermatitis	0.337	0.663
L21 Seborrhoeic dermatitis	0.337	0.663
L26 Exfoliative dermatitis	0.337	0.663
L22 Diaper [napkin] dermatitis	0.337	0.663
B15-B19 Viral hepatitis	0.339	0.661
E03.8 Other specified hypothyroidism	0.341	0.659
E87.7 Fluid overload	0.343	0.657
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.344	0.656
H72.1 Attic perforation of tympanic membrane	0.344	0.656
L20 Atopic dermatitis	0.345	0.655
E66.2 Extreme obesity with alveolar hypoventilation	0.346	0.654
H65.4 Other chronic nonsuppurative otitis media	0.346	0.654
D60-D64 Aplastic and other anaemias	0.347	0.653
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.347	0.653
B37.9 Candidiasis, unspecified	0.348	0.652
E06.5 Other chronic thyroiditis	0.349	0.651
E06.4 Drug-induced thyroiditis	0.349	0.651
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.349	0.651
E06.1 Subacute thyroiditis	0.349	0.651
E06.0 Acute thyroiditis	0.349	0.651
D86.0 Sarcoidosis of lung	0.349	0.651
B35.1 Tinea unguium	0.350	0.650
E85 Amyloidosis	0.350	0.650
M07.6 Other enteropathic arthropathies	0.350	0.649
M07.5 Arthropathy in ulcerative colitis	0.350	0.649
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.350	0.649
M07.2 Psoriatic spondylitis	0.350	0.649
M07.1 Arthritis mutilans	0.350	0.649
M07.0 Distal interphalangeal psoriatic arthropathy	0.350	0.649
M06.4 Inflammatory polyarthropathy	0.351	0.649
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.351	0.649
D52 Folate deficiency anaemia	0.353	0.647
B90-B94 Sequelae of infectious and parasitic diseases	0.353	0.646
L25 Unspecified contact dermatitis	0.356	0.644
D68.0 Von Willebrand's disease	0.356	0.644
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.357	0.643
E89.8 Other postprocedural endocrine and metabolic disorders	0.357	0.643
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.357	0.643
E89.5 Postprocedural testicular hypofunction	0.357	0.643
E89.4 Postprocedural ovarian failure	0.357	0.643
E89.1 Postprocedural hypoinsulinaemia	0.357	0.643
B37.4 Candidiasis of other urogenital sites	0.357	0.643
D66 Hereditary factor VIII deficiency	0.358	0.641
M91-M94 Chondropathies	0.359	0.641
D67 Hereditary factor IX deficiency	0.360	0.640
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.360	0.640
B34.3 Parvovirus infection, unspecified	0.360	0.639
B34.2 Coronavirus infection, unspecified	0.360	0.639
B34.1 Enterovirus infection, unspecified	0.360	0.639
B34.0 Adenovirus infection, unspecified	0.360	0.639
E22 Hyperfunction of pituitary gland	0.361	0.639
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.362	0.638
D51 Vitamin B12 deficiency anaemia	0.362	0.638
B65-B83 Helminthiases	0.362	0.638
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.362	0.638
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.362	0.638
M45.X6 Ankylosing spondylitis (Lumbar region)	0.362	0.638
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.362	0.638
M45.X4 Ankylosing spondylitis (Thoracic region)	0.362	0.638
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.362	0.638
M45.X2 Ankylosing spondylitis (Cervical region)	0.362	0.638
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.362	0.638
M99 Biomechanical lesions, not elsewhere classified	0.363	0.637
B37.1 Pulmonary candidiasis	0.363	0.637
M06.3 Rheumatoid nodule	0.364	0.636
B85-B89 Pediculosis, acariasis and other infestations	0.364	0.636
E12 Malnutrition-related diabetes mellitus	0.366	0.634
B37.2 Candidiasis of skin and nail	0.366	0.634
F31 Bipolar affective disorder	0.368	0.632
D69 Purpura and other haemorrhagic conditions	0.368	0.632
E89.3 Postprocedural hypopituitarism	0.369	0.631
E05.9 Thyrotoxicosis, unspecified	0.369	0.631
M49 Spondylopathies in diseases classified elsewhere	0.370	0.630
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.372	0.628
D50.8 Other iron deficiency anaemias	0.373	0.627
L23 Allergic contact dermatitis	0.373	0.627
E07 Other disorders of thyroid	0.373	0.627
M60-M63 Disorders of muscles	0.374	0.626
E87.4 Mixed disorder of acid-base balance	0.375	0.625
B99 Other and unspecified infectious diseases	0.375	0.625
L05.0 Pilonidal cyst with abscess	0.377	0.623
H65.3 Chronic mucoid otitis media	0.380	0.620
D70-D77 Other diseases of blood and blood-forming organs	0.381	0.619
D59 Acquired haemolytic anaemia	0.381	0.619
B34.4 Papovirus infection, unspecified	0.382	0.618
E05.5 Thyroid crisis or storm	0.384	0.615
E05.4 Thyrotoxicosis factitia	0.384	0.615
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.384	0.615
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.384	0.615
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.385	0.615
E73.9 Lactose intolerance, unspecified	0.385	0.614
L29.8 Other pruritus	0.386	0.614
L27.0 Generalised skin eruption due to drugs and medicaments	0.387	0.613
E10.0 With coma	0.387	0.613
E10.7 With multiple complications	0.387	0.612
L29.9 Pruritus, unspecified	0.388	0.612
L30.8 Other specified dermatitis	0.388	0.612
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.389	0.611
F42 Obsessive-compulsive disorder	0.389	0.610
M05.8 Other seropositive rheumatoid arthritis	0.390	0.610
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.390	0.610
M05.2 Rheumatoid vasculitis	0.390	0.610
M05.1 Rheumatoid lung disease	0.390	0.610
M05.0 Felty's syndrome	0.390	0.610
E89.2 Postprocedural hypoparathyroidism	0.390	0.610
L08.8 Other specified local infections of skin and subcutaneous tissue	0.391	0.609
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.392	0.608
M95.8 Other specified acquired deformities of musculoskeletal system	0.392	0.608
M95.5 Acquired deformity of pelvis	0.392	0.608
M95.4 Acquired deformity of chest and rib	0.392	0.608
M95.3 Acquired deformity of neck	0.392	0.608
M95.2 Other acquired deformity of head	0.392	0.608
M95.1 Cauliflower ear	0.392	0.608
M07.38 Other psoriatic arthropathies (Other)	0.393	0.607
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.393	0.607
M07.36 Other psoriatic arthropathies (Lower leg)	0.393	0.607
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.393	0.607
M07.34 Other psoriatic arthropathies (Hand)	0.393	0.607
M07.33 Other psoriatic arthropathies (Forearm)	0.393	0.607
M07.32 Other psoriatic arthropathies (Upper arm)	0.393	0.607
M07.31 Other psoriatic arthropathies (Shoulder region)	0.393	0.607
H65.1 Other acute nonsuppurative otitis media	0.394	0.606
H65.0 Acute serous otitis media	0.394	0.606
E27.4 Other and unspecified adrenocortical insufficiency	0.394	0.606
Chapter IX Diseases of the circulatory system	0.395	0.605
D68.2 Hereditary deficiency of other clotting factors	0.399	0.601
L29.3 Anogenital pruritus, unspecified	0.402	0.598
L29.1 Pruritus scroti	0.402	0.598
L08.1 Erythrasma	0.402	0.597
L08.0 Pyoderma	0.402	0.597
H69 Other disorders of Eustachian tube	0.403	0.597
D53 Other nutritional anaemias	0.403	0.597
F70-F79 Mental retardation	0.404	0.596
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.404	0.596
H82 Vertiginous syndromes in diseases classified elsewhere	0.405	0.595
D84 Other immunodeficiencies	0.406	0.594
D83 Common variable immunodeficiency	0.406	0.594
D82 Immunodeficiency associated with other major defects	0.406	0.594
D81 Combined immunodeficiencies	0.406	0.594
M30 Polyarteritis nodosa and related conditions	0.406	0.594
M34.9 Systemic sclerosis, unspecified	0.407	0.593
D68.4 Acquired coagulation factor deficiency	0.410	0.590
D68.1 Hereditary factor XI deficiency	0.410	0.590
L42 Pityriasis rosea	0.411	0.589
M35.9 Systemic involvement of connective tissue, unspecified	0.412	0.588
M35.8 Other specified systemic involvement of connective tissue	0.412	0.588
M35.6 Relapsing panniculitis [Weber-Christian]	0.412	0.588
M35.5 Multifocal fibrosclerosis	0.412	0.588
M35.4 Diffuse (eosinophilic) fasciitis	0.412	0.588
M35.2 Behcet's disease	0.412	0.588
M35.1 Other overlap syndromes	0.412	0.588
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.414	0.586
M32 Systemic lupus erythematosus	0.414	0.586
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions	0.416	0.584
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases	0.416	0.584
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms	0.416	0.584
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases	0.416	0.584
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.416	0.584
M22 Disorders of patella	0.416	0.584
M00 Pyogenic arthritis	0.416	0.584
F81 Specific developmental disorders of scholastic skills	0.417	0.583
H72.8 Other perforations of tympanic membrane	0.417	0.583
E14.9 Without complications	0.417	0.583
M06.08 Seronegative rheumatoid arthritis (Other)	0.418	0.581
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.418	0.581
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.418	0.581
M06.04 Seronegative rheumatoid arthritis (Hand)	0.418	0.581
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.418	0.581
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.418	0.581
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.418	0.581
B35.3 Tinea pedis	0.419	0.581
E87.5 Hyperkalaemia	0.420	0.580
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.421	0.579
E35 Disorders of endocrine glands in diseases classified elsewhere	0.422	0.578
E32 Diseases of thymus	0.422	0.578
E31 Polyglandular dysfunction	0.422	0.578
E30 Disorders of puberty, not elsewhere classified	0.422	0.578
E25 Adrenogenital disorders	0.422	0.578
E20 Hypoparathyroidism	0.422	0.578
E83 Disorders of mineral metabolism	0.422	0.578
F43 Reaction to severe stress, and adjustment disorders	0.422	0.578
M46.9 Inflammatory spondylopathy, unspecified	0.423	0.577
F05 Delirium, not induced by alcohol and other psychoactive substances	0.425	0.575
E10.8 With unspecified complications	0.426	0.574
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.426	0.574
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.427	0.573
E26 Hyperaldosteronism	0.429	0.571
H72.2 Other marginal perforations of tympanic membrane	0.430	0.570
F20 Schizophrenia	0.431	0.569
L40.0 Psoriasis vulgaris	0.431	0.569
B37.3 Candidiasis of vulva and vagina	0.431	0.568
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.431	0.568
D64 Other anaemias	0.433	0.566
B35.9 Dermatophytosis, unspecified	0.434	0.566
B35.8 Other dermatophytoses	0.434	0.566
B35.6 Tinea cruris	0.434	0.566
B35.5 Tinea imbricata	0.434	0.566
B35.4 Tinea corporis	0.434	0.566
B35.2 Tinea manuum	0.434	0.566
B35.0 Tinea barbae and tinea capitis	0.434	0.566
E87.3 Alkalosis	0.435	0.564
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.437	0.563
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.437	0.562
L43 Lichen planus	0.438	0.562
M10 Gout	0.439	0.561
A30-A49 Other bacterial diseases	0.441	0.559
A80-A89 Viral infections of the central nervous system	0.442	0.558
F99-F99 Unspecified mental disorder	0.442	0.558
I60-I69 Cerebrovascular diseases	0.443	0.557
F42.9 Obsessive-compulsive disorder, unspecified	0.446	0.554
E27.5 Adrenomedullary hyperfunction	0.447	0.553
E27.3 Drug-induced adrenocortical insufficiency	0.447	0.553
E27.2 Addisonian crisis	0.447	0.553
E27.0 Other adrenocortical overactivity	0.447	0.553
E87.0 Hyperosmolality and hypernatraemia	0.447	0.553
D68.6 Other Thrombophilia	0.447	0.552
L30.9 Dermatitis, unspecified	0.448	0.552
F30 Manic episode	0.448	0.552
I70-I79 Diseases of arteries, arterioles and capillaries	0.449	0.551
H83.0 Labyrinthitis	0.449	0.551
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.449	0.551
E10.6 With other specified complications	0.450	0.550
E73.8 Other lactose intolerance	0.452	0.548
E73.1 Secondary lactase deficiency	0.452	0.548
E73.0 Congenital lactase deficiency	0.452	0.548
M13 Other arthritis	0.452	0.548
F22 Persistent delusional disorders	0.452	0.548
D86.3 Sarcoidosis of skin	0.453	0.547
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.453	0.547
D86.1 Sarcoidosis of lymph nodes	0.453	0.547
E87.6 Hypokalaemia	0.453	0.547
M34.1 CR(E)ST syndrome	0.453	0.547
M14.6 Neuropathic arthropathy	0.454	0.546
M33 Dermatopolymyositis	0.454	0.545
D57 Sickle-cell disorders	0.454	0.545
D56 Thalassaemia	0.454	0.545
D55 Anaemia due to enzyme disorders	0.454	0.545
B95-B98 Bacterial, viral and other infectious agents	0.455	0.545
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.456	0.544
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.456	0.544
E80.4 Gilbert's syndrome	0.456	0.544
E88.9 Metabolic disorder, unspecified	0.457	0.543
E88.8 Other specified metabolic disorders	0.457	0.543
E88.3 Tumour lysis syndrome	0.457	0.543
E88.1 Lipodystrophy, not elsewhere classified	0.457	0.543
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.457	0.543
F60 Specific personality disorders	0.458	0.542
F40 Phobic anxiety disorders	0.458	0.542
B49 Unspecified mycosis	0.459	0.541
B25.9 Cytomegaloviral disease, unspecified	0.460	0.540
A59 Trichomoniasis	0.460	0.540
A56 Other sexually transmitted chlamydial diseases	0.460	0.540
A54 Gonococcal infection	0.460	0.540
A53 Other and unspecified syphilis	0.460	0.540
A52 Late syphilis	0.460	0.540
A51 Early syphilis	0.460	0.540
A50 Congenital syphilis	0.460	0.540
A64 Unspecified sexually transmitted disease	0.460	0.540
A58 Granuloma inguinale	0.460	0.540
A57 Chancroid	0.460	0.540
A55 Chlamydial lymphogranuloma (venereum)	0.460	0.540
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.460	0.539
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.460	0.539
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.460	0.539
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.460	0.539
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.460	0.539
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.460	0.539

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations