TreeWAS – Variant ID: rs2619566

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.695	0.305
I08 Multiple valve diseases	0.000	0.714	0.286
I08.8 Other multiple valve diseases	0.000	0.727	0.273
I08.0 Disorders of both mitral and aortic valves	0.000	0.727	0.273
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.782	0.218
I08.9 Multiple valve disease, unspecified	0.000	0.799	0.201
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.893	0.107
I05-I09 Chronic rheumatic heart diseases	0.000	0.950	0.050
M35.3 Polymyalgia rheumatica	0.000	0.965	0.035
I07 Rheumatic tricuspid valve diseases	0.000	0.965	0.034
I09 Other rheumatic heart diseases	0.000	0.966	0.034
I06 Rheumatic aortic valve diseases	0.000	0.966	0.033
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.971	0.029
I06.1 Rheumatic aortic insufficiency	0.000	0.974	0.025
I07.9 Tricuspid valve disease, unspecified	0.000	0.975	0.025
I07.8 Other tricuspid valve diseases	0.000	0.975	0.025
I07.2 Tricuspid stenosis with insufficiency	0.000	0.975	0.025
I07.0 Tricuspid stenosis	0.000	0.975	0.025
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.975	0.024
I09.8 Other specified rheumatic heart diseases	0.000	0.976	0.024
I09.2 Chronic rheumatic pericarditis	0.000	0.976	0.024
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.976	0.024
I09.0 Rheumatic myocarditis	0.000	0.976	0.024
I06.8 Other rheumatic aortic valve diseases	0.000	0.976	0.024
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.976	0.024
I07.1 Tricuspid insufficiency	0.000	0.977	0.023
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.977	0.023
M22.2 Patellofemoral disorders	0.000	0.978	0.022
M23 Internal derangement of knee	0.000	0.978	0.022
M35 Other systemic involvement of connective tissue	0.000	0.978	0.022
I09.9 Rheumatic heart disease, unspecified	0.000	0.978	0.021
I06.0 Rheumatic aortic stenosis	0.000	0.978	0.021
M23.6 Other spontaneous disruption of ligament(s) of knee	0.000	0.979	0.021
M20-M25 Other joint disorders	0.000	0.979	0.021
I05 Rheumatic mitral valve diseases	0.000	0.979	0.020
M22 Disorders of patella	0.000	0.980	0.020
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.980	0.020
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.981	0.019
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.981	0.019
M23.8 Other internal derangements of knee	0.000	0.982	0.018
M23.5 Chronic instability of knee	0.000	0.982	0.018
M23.9 Internal derangement of knee, unspecified	0.000	0.982	0.017
M25 Other joint disorders, not elsewhere classified	0.000	0.983	0.017
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.983	0.017
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.983	0.017
M25.9 Joint disorder, unspecified	0.000	0.983	0.017
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.983	0.017
M21 Other acquired deformities of limbs	0.000	0.983	0.017
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.983	0.017
M35.8 Other specified systemic involvement of connective tissue	0.000	0.984	0.016
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.984	0.016
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.984	0.016
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.984	0.016
M35.5 Multifocal fibrosclerosis	0.000	0.984	0.016
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.984	0.016
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.984	0.016
M35.2 Behcet's disease	0.000	0.984	0.015
I05.8 Other mitral valve diseases	0.000	0.984	0.015
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.985	0.015
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.985	0.015
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.985	0.015
M32 Systemic lupus erythematosus	0.000	0.985	0.015
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.985	0.015
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.985	0.015
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.000	0.985	0.015
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.000	0.985	0.015
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.000	0.985	0.015
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.985	0.015
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.985	0.015
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.985	0.015
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.000	0.985	0.015
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.985	0.015
M23.0 Cystic meniscus	0.000	0.985	0.015
M30 Polyarteritis nodosa and related conditions	0.000	0.985	0.015
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.985	0.015
M23.4 Loose body in knee	0.000	0.985	0.015
M23.1 Discoid meniscus (congenital)	0.000	0.985	0.015
I05.2 Mitral stenosis with insufficiency	0.000	0.985	0.014
M22.9 Disorder of patella, unspecified	0.000	0.985	0.015
M21.0 Valgus deformity, not elsewhere classified	0.000	0.985	0.015
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.985	0.015
M22.1 Recurrent subluxation of patella	0.000	0.985	0.014
M22.4 Chondromalacia patellae	0.000	0.985	0.015
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.985	0.014
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.986	0.014
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.986	0.014
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.986	0.014
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.986	0.014
I05.1 Rheumatic mitral insufficiency	0.000	0.986	0.014
M35.1 Other overlap syndromes	0.000	0.986	0.014
M22.3 Other derangements of patella	0.000	0.986	0.014
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.986	0.014
M34 Systemic sclerosis	0.000	0.986	0.014
M25.0 Haemarthrosis	0.000	0.986	0.014
M22.0 Recurrent dislocation of patella	0.000	0.986	0.014
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.986	0.014
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.986	0.014
M21.2 Flexion deformity	0.000	0.986	0.014
M25.3 Other instability of joint	0.000	0.986	0.014
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.986	0.014
M25.94 Joint disorder, unspecified (Hand)	0.000	0.986	0.014
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.986	0.014
M21.7 Unequal limb length (acquired)	0.000	0.987	0.013
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.987	0.013
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.987	0.013
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.987	0.013
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.987	0.013
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.987	0.013
M33 Dermatopolymyositis	0.000	0.987	0.013
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.987	0.013
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.987	0.013
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.987	0.013
M35.7 Hypermobility syndrome	0.000	0.987	0.013
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.987	0.013
M25.4 Effusion of joint	0.000	0.987	0.013
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.987	0.013
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.987	0.013
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.000	0.987	0.013
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.000	0.987	0.013
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.000	0.987	0.013
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.987	0.013
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.987	0.013
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.000	0.987	0.013
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.987	0.013
M21.4 Flat foot [pes planus] (acquired)	0.000	0.987	0.013
M25.2 Flail joint	0.000	0.987	0.013
M25.1 Fistula of joint	0.000	0.987	0.013
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.987	0.012
M21.26 Flexion deformity (Lower leg)	0.000	0.987	0.012
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.988	0.012
M21.8 Other specified acquired deformities of limbs	0.000	0.988	0.012
M25.98 Joint disorder, unspecified (Other)	0.000	0.988	0.012
M23.41 Loose body in knee-Ant lig/hrn men	0.000	0.988	0.012
M25.77 Osteophyte (Ankle and foot)	0.000	0.988	0.012
M21.9 Acquired deformity of limb, unspecified	0.000	0.988	0.012
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.988	0.012
M20 Acquired deformities of fingers and toes	0.000	0.988	0.012
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.000	0.988	0.012
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.988	0.012
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.988	0.012
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.988	0.012
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.988	0.012
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.988	0.012
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.000	0.988	0.012
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.988	0.011
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.988	0.012
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.988	0.011
M25.06 Haemarthrosis (Lower leg)	0.000	0.988	0.011
M21.6 Other acquired deformities of ankle and foot	0.000	0.988	0.011
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.988	0.011
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.988	0.011
M25.7 Osteophyte	0.000	0.988	0.011
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.000	0.989	0.011
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.989	0.011
M25.34 Other instability of joint (Hand)	0.000	0.989	0.011
M34.0 Progressive systemic sclerosis	0.000	0.989	0.011
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.989	0.011
M21.3 Wrist or foot drop (acquired)	0.000	0.989	0.011
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.989	0.011
M30.0 Polyarteritis nodosa	0.000	0.989	0.011
M23.07 Cystic meniscus-Capsular lig	0.000	0.989	0.011
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.000	0.989	0.011
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.989	0.011
M23.00 Cystic meniscus (Multiple sites)	0.000	0.989	0.011
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.989	0.011
M30.2 Juvenile polyarteritis	0.000	0.989	0.011
M23.47 Loose body in knee-Capsular lig	0.000	0.989	0.011
M23.45 Loose body in knee-Pst hrn lat men	0.000	0.989	0.011
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.000	0.989	0.011
M23.17 Discoid meniscus (congenital)-Capsular lig	0.000	0.989	0.011
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.000	0.989	0.011
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.989	0.011
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.989	0.011
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.989	0.011
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.989	0.011
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.000	0.989	0.011
M23.49 Loose body in knee-Unspec lig/men	0.000	0.989	0.011
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.989	0.011
M23.44 Loose body in knee-Lat lig/ant men	0.000	0.989	0.011
M25.47 Effusion of joint (Ankle and foot)	0.000	0.989	0.011
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.989	0.011
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.989	0.011
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.989	0.011
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.989	0.011
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.989	0.011
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.989	0.011
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.989	0.011
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.989	0.011
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.989	0.011
M23.46 Loose body in knee-O/unsp lat men	0.000	0.989	0.011
M23.42 Loose body in knee-Pst lig/hrn men	0.000	0.989	0.011
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.989	0.011
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.989	0.011
M25.33 Other instability of joint (Forearm)	0.000	0.989	0.011
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.989	0.010
M24 Other specific joint derangements	0.000	0.989	0.011
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.989	0.010
M36.3 Arthropathy in other blood disorders	0.000	0.989	0.010
M36.2 Haemophilic arthropathy	0.000	0.989	0.010
M36.1 Arthropathy in neoplastic disease	0.000	0.989	0.010
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.989	0.010
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.989	0.010
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.989	0.011
M25.40 Effusion of joint (Multiple sites)	0.000	0.989	0.010
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.989	0.010
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.989	0.010
M25.36 Other instability of joint (Lower leg)	0.000	0.989	0.010
M34.8 Other forms of systemic sclerosis	0.000	0.989	0.010
M32.8 Other forms of systemic lupus erythematosus	0.000	0.990	0.010
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.990	0.010
M25.8 Other specified joint disorders	0.000	0.990	0.010
I05.9 Mitral valve disease, unspecified	0.001	0.990	0.010
M25.09 Haemarthrosis (Site unspecified)	0.000	0.990	0.010
M25.08 Haemarthrosis (Other)	0.000	0.990	0.010
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.990	0.010
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.990	0.010
M25.04 Haemarthrosis (Hand)	0.000	0.990	0.010
M25.03 Haemarthrosis (Forearm)	0.000	0.990	0.010
M25.02 Haemarthrosis (Upper arm)	0.000	0.990	0.010
M25.01 Haemarthrosis (Shoulder region)	0.000	0.990	0.010
M25.00 Haemarthrosis (Multiple sites)	0.000	0.990	0.010
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.990	0.010
M21.24 Flexion deformity (Hand)	0.000	0.990	0.010
M21.23 Flexion deformity (Forearm)	0.000	0.990	0.010
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.990	0.010
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.990	0.010
M21.29 Flexion deformity (Site unspecified)	0.000	0.990	0.010
M21.28 Flexion deformity (Other)	0.000	0.990	0.010
M21.21 Flexion deformity (Shoulder region)	0.000	0.990	0.010
M25.39 Other instability of joint (Site unspecified)	0.000	0.990	0.010
M25.38 Other instability of joint (Other)	0.000	0.990	0.010
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.990	0.010
M25.32 Other instability of joint (Upper arm)	0.000	0.990	0.010
M25.30 Other instability of joint (Multiple sites)	0.000	0.990	0.010
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.990	0.010
M25.31 Other instability of joint (Shoulder region)	0.000	0.990	0.010
M20.3 Other deformity of hallux (acquired)	0.000	0.990	0.010
M21.20 Flexion deformity (Multiple sites)	0.000	0.990	0.010
M25.43 Effusion of joint (Forearm)	0.000	0.990	0.010
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.990	0.010
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.990	0.010
M25.41 Effusion of joint (Shoulder region)	0.000	0.990	0.010
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.990	0.010
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.990	0.010
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.990	0.010
M21.78 Unequal limb length (acquired)-Other	0.000	0.990	0.010
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.990	0.010
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.990	0.010
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.990	0.010
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.990	0.010
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.990	0.010
M23.40 Loose body in knee-Mult sites	0.000	0.990	0.010
M33.0 Juvenile dermatomyositis	0.000	0.990	0.009
M23.43 Loose body in knee-Med lig/oth men	0.000	0.990	0.009
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.990	0.010
M20.5 Other deformities of toe(s) (acquired)	0.000	0.990	0.010
M35.0 Sicca syndrome [Sjogren]	0.000	0.990	0.009
M25.49 Effusion of joint (Site unspecified)	0.000	0.990	0.009
M25.48 Effusion of joint (Other)	0.000	0.990	0.009
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.000	0.990	0.009
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.991	0.009
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.991	0.009
M25.19 Fistula of joint (Site unspecified)	0.000	0.991	0.009
M25.18 Fistula of joint (Other)	0.000	0.991	0.009
M25.17 Fistula of joint (Ankle and foot)	0.000	0.991	0.009
M25.16 Fistula of joint (Lower leg)	0.000	0.991	0.009
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.991	0.009
M25.14 Fistula of joint (Hand)	0.000	0.991	0.009
M25.13 Fistula of joint (Forearm)	0.000	0.991	0.009
M25.12 Fistula of joint (Upper arm)	0.000	0.991	0.009
M25.11 Fistula of joint (Shoulder region)	0.000	0.991	0.009
M25.10 Fistula of joint (Multiple sites)	0.000	0.991	0.009
M25.29 Flail joint (Site unspecified)	0.000	0.991	0.009
M25.28 Flail joint (Other)	0.000	0.991	0.009
M25.27 Flail joint (Ankle and foot)	0.000	0.991	0.009
M25.26 Flail joint (Lower leg)	0.000	0.991	0.009
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.991	0.009
M25.24 Flail joint (Hand)	0.000	0.991	0.009
M25.23 Flail joint (Forearm)	0.000	0.991	0.009
M25.22 Flail joint (Upper arm)	0.000	0.991	0.009
M25.21 Flail joint (Shoulder region)	0.000	0.991	0.009
M25.20 Flail joint (Multiple sites)	0.000	0.991	0.009
M21.27 Flexion deformity (Ankle and foot)	0.000	0.991	0.009
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.991	0.009
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.991	0.009
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.991	0.009
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.991	0.009
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.991	0.009
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.991	0.009
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.991	0.009
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.991	0.009
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.991	0.009
M21.22 Flexion deformity (Upper arm)	0.000	0.991	0.009
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.991	0.009
M25.44 Effusion of joint (Hand)	0.000	0.991	0.009
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.991	0.009
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.991	0.009
M33.1 Other dermatomyositis	0.000	0.991	0.009
M24.6 Ankylosis of joint	0.000	0.991	0.009
M33.9 Dermatopolymyositis, unspecified	0.000	0.991	0.009
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.991	0.009
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.991	0.009
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.991	0.009
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.991	0.009
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.991	0.009
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.991	0.009
M25.79 Osteophyte (Site unspecified)	0.000	0.991	0.009
I05.0 Mitral stenosis	0.001	0.991	0.008
M33.2 Polymyositis	0.000	0.991	0.009
M31 Other necrotising vasculopathies	0.000	0.991	0.009
M34.1 CR(E)ST syndrome	0.000	0.991	0.009
M20.4 Other hammer toe(s) (acquired)	0.000	0.991	0.009
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.991	0.009
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.991	0.009
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.991	0.009
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.991	0.009
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.991	0.009
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.991	0.009
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.991	0.009
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.991	0.009
M34.9 Systemic sclerosis, unspecified	0.000	0.991	0.009
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.991	0.008
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.991	0.008
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.991	0.008
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.991	0.008
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.991	0.008
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.991	0.008
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.991	0.008
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.991	0.008
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.991	0.008
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.991	0.008
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.991	0.008
M25.84 Other specified joint disorders (Hand)	0.000	0.991	0.008
M24.5 Contracture of joint	0.000	0.991	0.008
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.991	0.008
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.991	0.008
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.991	0.008
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.991	0.008
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.991	0.008
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.991	0.008
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.991	0.008
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.991	0.008
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.991	0.008
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.991	0.008
M25.70 Osteophyte (Multiple sites)	0.000	0.991	0.008
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.992	0.008
M25.37 Other instability of joint (Ankle and foot)	0.000	0.992	0.008
M25.72 Osteophyte (Upper arm)	0.000	0.992	0.008
M25.88 Other specified joint disorders (Other)	0.000	0.992	0.008
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.992	0.008
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.992	0.008
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.000	0.992	0.008
M24.1 Other articular cartilage disorders	0.000	0.992	0.008
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.992	0.008
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.992	0.008
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.992	0.008
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.992	0.008
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.992	0.008
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.992	0.008
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.992	0.008
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.992	0.008
M25.73 Osteophyte (Forearm)	0.000	0.992	0.008
M23.3 Other meniscus derangements	0.000	0.992	0.008
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.992	0.008
M25.42 Effusion of joint (Upper arm)	0.000	0.992	0.008
M25.76 Osteophyte (Lower leg)	0.000	0.992	0.008
M20.0 Deformity of finger(s)	0.000	0.992	0.008
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.992	0.008
M24.66 Ankylosis of joint (Lower leg)	0.000	0.992	0.008
M25.82 Other specified joint disorders (Upper arm)	0.000	0.992	0.008
M25.74 Osteophyte (Hand)	0.000	0.992	0.008
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.992	0.008
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.992	0.008
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.992	0.008
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.992	0.008
M24.7 Protrusio acetabuli	0.000	0.992	0.008
M24.2 Disorder of ligament	0.000	0.992	0.008
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.992	0.008
M24.9 Joint derangement, unspecified	0.000	0.992	0.007
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.992	0.007
M24.67 Ankylosis of joint (Ankle and foot)	0.000	0.992	0.007
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.008	0.992	0.000
K04.8 Radicular cyst	0.000	0.993	0.007
M25.86 Other specified joint disorders (Lower leg)	0.000	0.993	0.007
M21.1 Varus deformity, not elsewhere classified	0.000	0.993	0.007
M31.3 Wegener's granulomatosis	0.000	0.993	0.007
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.993	0.007
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.993	0.007
M24.52 Contracture of joint (Upper arm)	0.000	0.993	0.007
M24.0 Loose body in joint	0.000	0.993	0.007
M22.8 Other disorders of patella	0.001	0.993	0.006
Q61.3 Polycystic kidney, unspecified	0.007	0.993	0.000
M25.78 Osteophyte (Other)	0.000	0.993	0.007
M24.64 Ankylosis of joint (Hand)	0.000	0.993	0.007
M31.8 Other specified necrotising vasculopathies	0.000	0.993	0.007
M31.7 Microscopic polyangiitis	0.000	0.993	0.007
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.993	0.007
M24.69 Ankylosis of joint (Site unspecified)	0.000	0.993	0.007
M24.68 Ankylosis of joint (Other)	0.000	0.993	0.007
M24.63 Ankylosis of joint (Forearm)	0.000	0.993	0.007
M24.62 Ankylosis of joint (Upper arm)	0.000	0.993	0.007
M24.61 Ankylosis of joint (Shoulder region)	0.000	0.993	0.007
M24.60 Ankylosis of joint (Multiple sites)	0.000	0.993	0.007
M31.1 Thrombotic microangiopathy	0.000	0.993	0.007
M24.51 Contracture of joint (Shoulder region)	0.000	0.993	0.007
M31.2 Lethal midline granuloma	0.000	0.993	0.007
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.007	0.993	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.993	0.007
M31.9 Necrotising vasculopathy, unspecified	0.000	0.993	0.006
M24.56 Contracture of joint (Lower leg)	0.000	0.993	0.007
M25.83 Other specified joint disorders (Forearm)	0.000	0.993	0.006
Q61 Cystic kidney disease	0.007	0.993	0.000
M24.57 Contracture of joint (Ankle and foot)	0.000	0.993	0.006
M31.0 Hypersensitivity angiitis	0.000	0.993	0.006
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.993	0.007
Q61.0 Congenital single renal cyst	0.006	0.994	0.000
M24.23 Disorder of ligament (Forearm)	0.000	0.994	0.006
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.994	0.006
M24.59 Contracture of joint (Site unspecified)	0.000	0.994	0.006
M24.58 Contracture of joint (Other)	0.000	0.994	0.006
M24.53 Contracture of joint (Forearm)	0.000	0.994	0.006
M24.50 Contracture of joint (Multiple sites)	0.000	0.994	0.006
M24.14 Other articular cartilage disorders (Hand)	0.000	0.994	0.006
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.000	0.994	0.006
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.994	0.006
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.994	0.006
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.994	0.006
M24.18 Other articular cartilage disorders (Other)	0.000	0.994	0.006
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.994	0.006
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.994	0.006
M24.24 Disorder of ligament (Hand)	0.000	0.994	0.006
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.000	0.994	0.006
M23.37 Other meniscus derangements-Capsular lig	0.000	0.994	0.006
K04.7 Periapical abscess without sinus	0.000	0.994	0.006
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.994	0.006
M24.54 Contracture of joint (Hand)	0.000	0.994	0.006
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.000	0.994	0.006
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.000	0.994	0.006
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.000	0.994	0.006
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.994	0.006
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.000	0.994	0.006
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.000	0.994	0.006
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.000	0.994	0.006
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.000	0.994	0.006
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.000	0.994	0.006
K04 Diseases of pulp and periapical tissues	0.000	0.994	0.006
K86.2 Cyst of pancreas	0.000	0.994	0.006
M24.55 Contracture of joint (Pelvic region and thigh)	0.000	0.994	0.006
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.994	0.006
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.994	0.006
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.994	0.006
N80.0 Endometriosis of uterus	0.006	0.994	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.000	0.994	0.006
M24.91 Joint derangement, unspecified (Shoulder region)	0.000	0.994	0.006
M24.28 Disorder of ligament (Other)	0.000	0.994	0.006
M24.79 Protrusio acetabuli-Site unspec	0.000	0.994	0.006
M24.78 Protrusio acetabuli-Other	0.000	0.994	0.006
M24.77 Protrusio acetabuli-Ankle/foot	0.000	0.994	0.006
M24.76 Protrusio acetabuli-Lower leg	0.000	0.994	0.006
M24.74 Protrusio acetabuli-Hand	0.000	0.994	0.006
M24.73 Protrusio acetabuli-Forearm	0.000	0.994	0.006
M24.72 Protrusio acetabuli-Upper arm	0.000	0.994	0.006
M24.71 Protrusio acetabuli-Shldr region	0.000	0.994	0.006
M24.70 Protrusio acetabuli-Mult sites	0.000	0.994	0.006
M24.29 Disorder of ligament (Site unspecified)	0.000	0.994	0.006
M24.22 Disorder of ligament (Upper arm)	0.000	0.994	0.006
M24.20 Disorder of ligament (Multiple sites)	0.000	0.994	0.006
M24.99 Joint derangement, unspecified (Site unspecified)	0.000	0.994	0.005
M24.98 Joint derangement, unspecified (Other)	0.000	0.994	0.005
M24.97 Joint derangement, unspecified (Ankle and foot)	0.000	0.994	0.005
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.000	0.994	0.005
M24.93 Joint derangement, unspecified (Forearm)	0.000	0.994	0.005
M24.92 Joint derangement, unspecified (Upper arm)	0.000	0.994	0.005
M24.90 Joint derangement, unspecified (Multiple sites)	0.000	0.994	0.005
C34.3 Lower lobe, bronchus or lung	0.006	0.994	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.006	0.994	0.000
C82.0 Small cleaved cell, follicular	0.006	0.994	0.000
M24.03 Loose body in joint (Forearm)	0.000	0.994	0.005
C82.1 Mixed small cleaved and large cell, follicular	0.006	0.994	0.000
M24.26 Disorder of ligament (Lower leg)	0.000	0.994	0.005
M24.75 Protrusio acetabuli-Pelvic/thigh	0.000	0.994	0.005
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.994	0.005
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.994	0.005
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.994	0.005
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.994	0.005
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.994	0.005
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.994	0.005
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.994	0.005
M24.96 Joint derangement, unspecified (Lower leg)	0.000	0.994	0.005
C34 Malignant neoplasm of bronchus and lung	0.006	0.994	0.000
M24.04 Loose body in joint (Hand)	0.000	0.994	0.005
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.995	0.005
M24.21 Disorder of ligament (Shoulder region)	0.000	0.995	0.005
M24.25 Disorder of ligament (Pelvic region and thigh)	0.000	0.995	0.005
M24.94 Joint derangement, unspecified (Hand)	0.000	0.995	0.005
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.995	0.005
Q61.2 Polycystic kidney, adult type	0.005	0.995	0.000
C34.0 Main bronchus	0.005	0.995	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.005	0.995	0.000
K04.6 Periapical abscess with sinus	0.000	0.995	0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations