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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2621331
log Bayes Factor = 36.0046
Chromosome 6   position 32,780,470  (GRCh37) Explore rs2621331 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
C44.7 Skin of lower limb, including hip
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E20-E35 Disorders of other endocrine glands
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
G35 Multiple sclerosis
0.999 0.001 0.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
C44.6 Skin of upper limb, including shoulder
0.000 0.001 0.999
C44.3 Skin of other and unspecified parts of face
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.003 0.997
E05.9 Thyrotoxicosis, unspecified
0.000 0.005 0.995
E27 Other disorders of adrenal gland
0.000 0.009 0.991
E10.9 Without complications
0.000 0.015 0.985
E23 Hypofunction and other disorders of pituitary gland
0.000 0.017 0.983
E27.1 Primary adrenocortical insufficiency
0.000 0.026 0.974
E83.1 Disorders of iron metabolism
0.968 0.032 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.960 0.040 0.000
L57.0 Actinic keratosis
0.000 0.042 0.958
G37 Other demyelinating diseases of central nervous system
0.948 0.052 0.000
E10.2 With renal complications
0.000 0.057 0.943
C44.4 Skin of scalp and neck
0.000 0.063 0.937
C44.2 Skin of ear and external auricular canal
0.000 0.065 0.935
E10.1 With ketoacidosis
0.000 0.065 0.935
E23.7 Disorder of pituitary gland, unspecified
0.000 0.071 0.929
E24 Cushing's syndrome
0.000 0.075 0.925
E23.6 Other disorders of pituitary gland
0.000 0.075 0.925
G37.9 Demyelinating disease of central nervous system, unspecified
0.924 0.076 0.000
E10.5 With peripheral circulatory complications
0.000 0.087 0.913
E11 Non-insulin-dependent diabetes mellitus
0.000 0.101 0.899
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.109 0.891
E11.3 With ophthalmic complications
0.000 0.120 0.880
M07.3 Other psoriatic arthropathies
0.000 0.122 0.878
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.124 0.876
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.128 0.872
G37.8 Other specified demyelinating diseases of central nervous system
0.872 0.128 0.000
E06 Thyroiditis
0.000 0.149 0.851
L40.0 Psoriasis vulgaris
0.000 0.151 0.849
L40-L45 Papulosquamous disorders
0.000 0.152 0.848
C44.0 Skin of lip
0.000 0.153 0.847
L40.1 Generalised pustular psoriasis
0.000 0.158 0.842
E10.4 With neurological complications
0.000 0.164 0.836
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.172 0.828
L40.3 Pustulosis palmaris et plantaris
0.000 0.185 0.815
E10.0 With coma
0.000 0.193 0.807
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.193 0.807
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.197 0.803
E11.2 With renal complications
0.000 0.200 0.800
E28 Ovarian dysfunction
0.000 0.204 0.796
E29 Testicular dysfunction
0.000 0.210 0.790
L40.4 Guttate psoriasis
0.000 0.219 0.781
E24.0 Pituitary-dependent Cushing's disease
0.000 0.222 0.778
G36 Other acute disseminated demyelination
0.775 0.225 0.000
E06.3 Autoimmune thyroiditis
0.000 0.228 0.772
E24.2 Drug-induced Cushing's syndrome
0.000 0.228 0.772
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.230 0.770
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.236 0.764
E26 Hyperaldosteronism
0.000 0.243 0.757
E24.9 Cushing's syndrome, unspecified
0.000 0.249 0.751
L43 Lichen planus
0.000 0.259 0.741
E13 Other specified diabetes mellitus
0.000 0.259 0.741
E23.0 Hypopituitarism
0.000 0.260 0.739
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.274 0.726
E10.7 With multiple complications
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.717
E32 Diseases of thymus
0.000 0.283 0.717
E31 Polyglandular dysfunction
0.000 0.283 0.717
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E11.0 With coma
0.000 0.285 0.715
E27.5 Adrenomedullary hyperfunction
0.000 0.289 0.711
E27.0 Other adrenocortical overactivity
0.000 0.289 0.711
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.292 0.708
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.295 0.705
E23.1 Drug-induced hypopituitarism
0.000 0.295 0.705
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.295 0.705
E27.2 Addisonian crisis
0.000 0.299 0.701
E05.8 Other thyrotoxicosis
0.000 0.312 0.688
E10.6 With other specified complications
0.000 0.313 0.686
E24.8 Other Cushing's syndrome
0.000 0.318 0.682
E25 Adrenogenital disorders
0.000 0.319 0.681
G37.5 Concentric sclerosis [Balo]
0.680 0.320 0.000
G37.4 Subacute necrotising myelitis
0.680 0.320 0.000
G37.2 Central pontine myelinolysis
0.680 0.320 0.000
G37.1 Central demyelination of corpus callosum
0.680 0.320 0.000
G37.0 Diffuse sclerosis
0.680 0.320 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.329 0.671
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.337 0.663
E24.3 Ectopic ACTH syndrome
0.000 0.337 0.663
E24.1 Nelson's syndrome
0.000 0.337 0.663
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.339 0.661
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.343 0.657
L43.9 Lichen planus, unspecified
0.000 0.348 0.652
E04 Other non-toxic goitre
0.000 0.349 0.651
E23.2 Diabetes insipidus
0.000 0.351 0.648
E06.9 Thyroiditis, unspecified
0.000 0.352 0.648
E11.7 With multiple complications
0.000 0.356 0.644
G36.0 Neuromyelitis optica [Devic]
0.642 0.358 0.000
E29.1 Testicular hypofunction
0.000 0.360 0.640
E11.6 With other specified complications
0.000 0.363 0.637
E11.8 With unspecified complications
0.000 0.364 0.636
E65-E68 Obesity and other hyperalimentation
0.000 0.365 0.635
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.369 0.631
M07.38 Other psoriatic arthropathies (Other)
0.000 0.370 0.630
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.370 0.630
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.370 0.630
E28.2 Polycystic ovarian syndrome
0.000 0.373 0.627
E27.9 Disorder of adrenal gland, unspecified
0.000 0.385 0.615
E40-E46 Malnutrition
0.000 0.387 0.613
E06.4 Drug-induced thyroiditis
0.000 0.390 0.610
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.390 0.610
E06.0 Acute thyroiditis
0.000 0.390 0.610
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.610 0.390 0.000
E06.5 Other chronic thyroiditis
0.000 0.391 0.609
L44 Other papulosquamous disorders
0.000 0.392 0.608
L41 Parapsoriasis
0.000 0.392 0.608
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.392 0.608
E20 Hypoparathyroidism
0.000 0.396 0.604
E28.3 Primary ovarian failure
0.000 0.400 0.600
E16 Other disorders of pancreatic internal secretion
0.000 0.406 0.594
E10.8 With unspecified complications
0.000 0.410 0.590
E11.5 With peripheral circulatory complications
0.000 0.410 0.590
E04.0 Non-toxic diffuse goitre
0.000 0.410 0.590
E26.0 Primary hyperaldosteronism
0.000 0.417 0.583
E34 Other endocrine disorders
0.000 0.425 0.575
E28.9 Ovarian dysfunction, unspecified
0.000 0.429 0.570
E28.8 Other ovarian dysfunction
0.000 0.429 0.570
E28.1 Androgen excess
0.000 0.429 0.570
E28.0 Oestrogen excess
0.000 0.429 0.570
E29.9 Testicular dysfunction, unspecified
0.000 0.434 0.566
E29.8 Other testicular dysfunction
0.000 0.434 0.566
E29.0 Testicular hyperfunction
0.000 0.434 0.566
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.438 0.562
L43.8 Other lichen planus
0.000 0.441 0.559
G36.9 Acute disseminated demyelination, unspecified
0.556 0.444 0.000
G36.8 Other specified acute disseminated demyelination
0.556 0.444 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.556 0.444 0.000
E13.3 With ophthalmic complications
0.000 0.448 0.552
L57.5 Actinic granuloma
0.000 0.448 0.552
L57.3 Poikiloderma of Civatte
0.000 0.448 0.552
L57.2 Cutis rhomboidalis nuchae
0.000 0.448 0.552
L57.1 Actinic reticuloid
0.000 0.448 0.552
E15 Nondiabetic hypoglycaemic coma
0.000 0.452 0.547
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.453 0.547
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.455 0.545
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.456 0.544
E26.9 Hyperaldosteronism, unspecified
0.000 0.457 0.543
E26.8 Other hyperaldosteronism
0.000 0.457 0.543
E26.1 Secondary hyperaldosteronism
0.000 0.457 0.543
L42 Pityriasis rosea
0.000 0.458 0.541
E21.3 Hyperparathyroidism, unspecified
0.000 0.459 0.541
E22 Hyperfunction of pituitary gland
0.000 0.460 0.540
E65 Localised adiposity
0.000 0.463 0.537
E13.9 Without complications
0.000 0.466 0.534
L43.3 Subacute (active) lichen planus
0.000 0.469 0.531
L43.2 Lichenoid drug reaction
0.000 0.469 0.531
L43.1 Bullous lichen planus
0.000 0.469 0.531
L43.0 Hypertrophic lichen planus
0.000 0.469 0.531
E13.8 With unspecified complications
0.000 0.469 0.531
E13.7 With multiple complications
0.000 0.469 0.531
E13.6 With other specified complications
0.000 0.469 0.531
E13.5 With peripheral circulatory complications
0.000 0.469 0.531
E13.4 With neurological complications
0.000 0.469 0.531
E13.2 With renal complications
0.000 0.469 0.531
E13.1 With ketoacidosis
0.000 0.469 0.531
E13.0 With coma
0.000 0.469 0.531
L40.8 Other psoriasis
0.000 0.473 0.527
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.514
E30.8 Other disorders of puberty
0.000 0.486 0.514
E30.1 Precocious puberty
0.000 0.486 0.514
E30.0 Delayed puberty
0.000 0.486 0.514
E31.9 Polyglandular dysfunction, unspecified
0.000 0.486 0.514
E31.8 Other polyglandular dysfunction
0.000 0.486 0.514
E31.1 Polyglandular hyperfunction
0.000 0.486 0.514
E31.0 Autoimmune polyglandular failure
0.000 0.486 0.514
E32.9 Disease of thymus, unspecified
0.000 0.486 0.514
E32.8 Other diseases of thymus
0.000 0.486 0.514
E32.1 Abscess of thymus
0.000 0.486 0.514
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.514
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.514
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.514
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E21.4 Other specified disorders of parathyroid gland
0.000 0.493 0.507
L55 Sunburn
0.000 0.495 0.505
E70-E90 Metabolic disorders
0.000 0.502 0.498
E04.2 Non-toxic multinodular goitre
0.000 0.502 0.498
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.502 0.498
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.503 0.496
E21.2 Other hyperparathyroidism
0.000 0.509 0.490
E25.9 Adrenogenital disorder, unspecified
0.000 0.511 0.488
E25.8 Other adrenogenital disorders
0.000 0.511 0.488
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.519 0.481
E07 Other disorders of thyroid
0.000 0.521 0.479
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.525 0.475
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.526 0.474
E06.1 Subacute thyroiditis
0.000 0.528 0.472
L10-L14 Bullous disorders
0.000 0.533 0.467
E04.8 Other specified non-toxic goitre
0.000 0.533 0.467
L58 Radiodermatitis
0.000 0.533 0.467
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.535 0.465
E78.2 Mixed hyperlipidaemia
0.000 0.538 0.462
E34.8 Other specified endocrine disorders
0.000 0.544 0.456
E67 Other hyperalimentation
0.000 0.544 0.456
E68 Sequelae of hyperalimentation
0.000 0.544 0.456
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.545 0.455
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.547 0.453
E16.2 Hypoglycaemia, unspecified
0.000 0.548 0.452
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.552 0.448
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.560 0.439
E45 Retarded development following protein-energy malnutrition
0.000 0.560 0.439
E43 Unspecified severe protein-energy malnutrition
0.000 0.560 0.439
E42 Marasmic kwashiorkor
0.000 0.560 0.439
E41 Nutritional marasmus
0.000 0.560 0.439
E40 Kwashiorkor
0.000 0.560 0.439
L41.9 Parapsoriasis, unspecified
0.000 0.564 0.436
L41.8 Other parapsoriasis
0.000 0.564 0.436
L41.5 Retiform parapsoriasis
0.000 0.564 0.436
L41.4 Large plaque parapsoriasis
0.000 0.564 0.436
L41.3 Small plaque parapsoriasis
0.000 0.564 0.436
L41.2 Lymphomatoid papulosis
0.000 0.564 0.436
L41.1 Pityriasis lichenoides chronica
0.000 0.564 0.436
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.564 0.436
L44.9 Papulosquamous disorder, unspecified
0.000 0.564 0.436
L44.8 Other specified papulosquamous disorders
0.000 0.564 0.436
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.564 0.436
L44.3 Lichen ruber moniliformis
0.000 0.564 0.436
L44.2 Lichen striatus
0.000 0.564 0.436
L44.1 Lichen nitidus
0.000 0.564 0.436
L44.0 Pityriasis rubra pilaris
0.000 0.564 0.436
E21.0 Primary hyperparathyroidism
0.000 0.565 0.435
E11.1 With ketoacidosis
0.000 0.566 0.434
E20.1 Pseudohypoparathyroidism
0.000 0.567 0.433
E20.0 Idiopathic hypoparathyroidism
0.000 0.567 0.433
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.570 0.430
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.574 0.426
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.574 0.426
E16.4 Abnormal secretion of gastrin
0.000 0.574 0.426
E16.3 Increased secretion of glucagon
0.000 0.574 0.426
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.574 0.426
L57.4 Cutis laxa senilis
0.000 0.577 0.422
E78.5 Hyperlipidaemia, unspecified
0.000 0.579 0.421
E78.6 Lipoprotein deficiency
0.000 0.580 0.420
E88 Other metabolic disorders
0.000 0.582 0.418
E34.5 Androgen resistance syndrome
0.000 0.587 0.412
E34.4 Constitutional tall stature
0.000 0.587 0.412
E34.3 Short stature, not elsewhere classified
0.000 0.587 0.412
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.587 0.412
E34.1 Other hypersecretion of intestinal hormones
0.000 0.587 0.412
E16.1 Other hypoglycaemia
0.000 0.593 0.407
E89.0 Postprocedural hypothyroidism
0.000 0.593 0.407
C44.9 Malignant neoplasm of skin, unspecified
0.001 0.602 0.398
E20.9 Hypoparathyroidism, unspecified
0.000 0.604 0.396
E22.1 Hyperprolactinaemia
0.000 0.606 0.394
L56.3 Solar urticaria
0.000 0.607 0.393
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.607 0.393
L56.1 Drug photoallergic response
0.000 0.607 0.393
L56.0 Drug phototoxic response
0.000 0.607 0.393
E78.1 Pure hyperglyceridaemia
0.000 0.608 0.392
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.612 0.387
E22.8 Other hyperfunction of pituitary gland
0.000 0.612 0.387
E11.4 With neurological complications
0.000 0.623 0.377
E79 Disorders of purine and pyrimidine metabolism
0.000 0.628 0.372
E20.8 Other hypoparathyroidism
0.000 0.629 0.371
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.631 0.369
L55.9 Sunburn, unspecified
0.000 0.637 0.362
L55.8 Other sunburn
0.000 0.637 0.362
L55.2 Sunburn of third degree
0.000 0.637 0.362
L55.1 Sunburn of second degree
0.000 0.637 0.362
L55.0 Sunburn of first degree
0.000 0.637 0.362
J45.9 Asthma, unspecified
0.362 0.638 0.000
E84 Cystic fibrosis
0.000 0.640 0.360
L56.4 Polymorphous light eruption
0.000 0.641 0.359
E04.9 Non-toxic goitre, unspecified
0.000 0.641 0.359
E77 Disorders of glycoprotein metabolism
0.000 0.643 0.357
E76 Disorders of glycosaminoglycan metabolism
0.000 0.643 0.357
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.643 0.357
E70 Disorders of aromatic amino-acid metabolism
0.000 0.643 0.357
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.643 0.357
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.644 0.356
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.644 0.356
L12 Pemphigoid
0.000 0.645 0.355
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.645 0.355
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.648 0.352
E88.3 Tumour lysis syndrome
0.000 0.649 0.351
E89.3 Postprocedural hypopituitarism
0.000 0.650 0.350
C44.5 Skin of trunk
0.000 0.650 0.350
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.651 0.349
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.653 0.347
E07.1 Dyshormogenetic goitre
0.000 0.656 0.344
E07.0 Hypersecretion of calcitonin
0.000 0.656 0.344
L11 Other acantholytic disorders
0.000 0.658 0.342
M07 Psoriatic and enteropathic arthropathies
0.000 0.663 0.337
E46 Unspecified protein-energy malnutrition
0.000 0.664 0.335
L10 Pemphigus
0.000 0.665 0.335
L14 Bullous disorders in diseases classified elsewhere
0.000 0.665 0.335
L58.1 Chronic radiodermatitis
0.000 0.665 0.335
L58.0 Acute radiodermatitis
0.000 0.665 0.335
C43 Malignant melanoma of skin
0.000 0.666 0.334
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.670 0.330
E07.8 Other specified disorders of thyroid
0.000 0.670 0.330
E78.4 Other hyperlipidaemia
0.000 0.670 0.330
E88.8 Other specified metabolic disorders
0.000 0.671 0.329
E34.0 Carcinoid syndrome
0.000 0.671 0.329
E88.2 Lipomatosis, not elsewhere classified
0.000 0.672 0.328
E67.8 Other specified hyperalimentation
0.000 0.673 0.327
E67.3 Hypervitaminosis D
0.000 0.673 0.327
E67.2 Megavitamin-B6 syndrome
0.000 0.673 0.327
E67.1 Hypercarotenaemia
0.000 0.673 0.327
E67.0 Hypervitaminosis A
0.000 0.673 0.327
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.675 0.325
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.678 0.322
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.679 0.321
E89.5 Postprocedural testicular hypofunction
0.000 0.679 0.321
E78.8 Other disorders of lipoprotein metabolism
0.000 0.682 0.318
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.685 0.315
E44.1 Mild protein-energy malnutrition
0.000 0.685 0.315
E44.0 Moderate protein-energy malnutrition
0.000 0.685 0.315
J45 Asthma
0.315 0.685 0.000
E89.4 Postprocedural ovarian failure
0.000 0.685 0.315
E78.3 Hyperchylomicronaemia
0.000 0.689 0.311
J45.0 Predominantly allergic asthma
0.304 0.696 0.000
E72 Other disorders of amino-acid metabolism
0.000 0.698 0.302
L60-L75 Disorders of skin appendages
0.000 0.699 0.301
E34.9 Endocrine disorder, unspecified
0.000 0.699 0.300
L13 Other bullous disorders
0.000 0.701 0.298
E74 Other disorders of carbohydrate metabolism
0.000 0.702 0.297
L58.9 Radiodermatitis, unspecified
0.000 0.704 0.296
E88.9 Metabolic disorder, unspecified
0.000 0.705 0.294
E50-E64 Other nutritional deficiencies
0.000 0.708 0.292
E89.1 Postprocedural hypoinsulinaemia
0.000 0.710 0.290
E73 Lactose intolerance
0.000 0.714 0.286
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.718 0.282
E80.4 Gilbert's syndrome
0.000 0.719 0.280
L12.9 Pemphigoid, unspecified
0.000 0.725 0.275
E83 Disorders of mineral metabolism
0.076 0.726 0.198
E89.2 Postprocedural hypoparathyroidism
0.000 0.727 0.272
E80.6 Other disorders of bilirubin metabolism
0.000 0.729 0.271
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.733 0.267
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.733 0.267
E79.1 Lesch-Nyhan syndrome
0.000 0.733 0.267
E03 Other hypothyroidism
0.000 0.733 0.266
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.734 0.266
E85 Amyloidosis
0.000 0.735 0.265
L50-L54 Urticaria and erythema
0.000 0.735 0.265
E84.9 Cystic fibrosis, unspecified
0.000 0.739 0.261
L12.1 Cicatricial pemphigoid
0.000 0.740 0.260
L71 Rosacea
0.000 0.740 0.260
E84.8 Cystic fibrosis with other manifestations
0.000 0.742 0.258
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.742 0.258
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.742 0.258
E22.0 Acromegaly and pituitary gigantism
0.000 0.743 0.257
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.744 0.256
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.744 0.256
E70.3 Albinism
0.000 0.744 0.256
E70.2 Disorders of tyrosine metabolism
0.000 0.744 0.256
E70.1 Other hyperphenylalaninaemias
0.000 0.744 0.256
E70.0 Classical phenylketonuria
0.000 0.744 0.256
E71.3 Disorders of fatty-acid metabolism
0.000 0.744 0.256
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.744 0.256
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.744 0.256
E71.0 Maple-syrup-urine disease
0.000 0.744 0.256
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.744 0.256
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.744 0.256
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.744 0.256
E76.2 Other mucopolysaccharidoses
0.000 0.744 0.256
E76.1 Mucopolysaccharidosis, type II
0.000 0.744 0.256
E76.0 Mucopolysaccharidosis, type I
0.000 0.744 0.256
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.744 0.256
E77.8 Other disorders of glycoprotein metabolism
0.000 0.744 0.256
E77.1 Defects in glycoprotein degradation
0.000 0.744 0.256
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.744 0.256
L12.8 Other pemphigoid
0.000 0.745 0.255
L12.3 Acquired epidermolysis bullosa
0.000 0.745 0.255
L12.2 Chronic bullous disease of childhood
0.000 0.745 0.255
L11.0 Acquired keratosis follicularis
0.000 0.746 0.254
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.747 0.253
E80.5 Crigler-Najjar syndrome
0.000 0.747 0.253
E80.3 Defects of catalase and peroxydase
0.000 0.747 0.253
E80.0 Hereditary erythropoietic porphyria
0.000 0.747 0.253
E75.6 Lipid storage disorder, unspecified
0.000 0.750 0.250
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.750 0.250
E75.3 Sphingolipidosis, unspecified
0.000 0.750 0.250
E75.1 Other gangliosidosis
0.000 0.750 0.250
E75.0 GM2 gangliosidosis
0.000 0.750 0.250
L12.0 Bullous pemphigoid
0.000 0.751 0.249
E75.2 Other sphingolipidosis
0.000 0.752 0.247
L11.9 Acantholytic disorder, unspecified
0.000 0.755 0.245
L11.8 Other specified acantholytic disorders
0.000 0.755 0.245
E75.5 Other lipid storage disorders
0.000 0.756 0.244
L11.1 Transient acantholytic dermatosis [Grover]
0.000 0.758 0.242
M07.5 Arthropathy in ulcerative colitis
0.000 0.758 0.242
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.758 0.242
M07.2 Psoriatic spondylitis
0.000 0.758 0.242
M07.1 Arthritis mutilans
0.000 0.758 0.242
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.758 0.242
L10.9 Pemphigus, unspecified
0.000 0.759 0.240
L10.8 Other pemphigus
0.000 0.759 0.240
L10.5 Drug-induced pemphigus
0.000 0.759 0.240
L10.4 Pemphigus erythematosus
0.000 0.759 0.240
L10.3 Brazilian pemphigus [fogo selvagem]
0.000 0.759 0.240
L10.2 Pemphigus foliaceus
0.000 0.759 0.240
L10.1 Pemphigus vegetans
0.000 0.759 0.240
L10.0 Pemphigus vulgaris
0.000 0.759 0.240
C43.9 Malignant melanoma of skin, unspecified
0.000 0.759 0.240
C43.8 Overlapping malignant melanoma of skin
0.000 0.761 0.239
C43.0 Malignant melanoma of lip
0.000 0.761 0.239
J45.8 Mixed asthma
0.238 0.762 0.000
L68 Hypertrichosis
0.000 0.763 0.237
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.766 0.234
J45.1 Nonallergic asthma
0.231 0.769 0.000
E80.1 Porphyria cutanea tarda
0.000 0.769 0.231
E51 Thiamine deficiency
0.000 0.770 0.229
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.773 0.226
L71.9 Rosacea, unspecified
0.000 0.774 0.226
M07.6 Other enteropathic arthropathies
0.000 0.774 0.226
L51 Erythema multiforme
0.000 0.776 0.224
L63 Alopecia areata
0.000 0.778 0.222
C43.4 Malignant melanoma of scalp and neck
0.000 0.778 0.222
L60 Nail disorders
0.000 0.781 0.219
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.783 0.217
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.783 0.217
E72.5 Disorders of glycine metabolism
0.000 0.783 0.217
E72.4 Disorders of ornithine metabolism
0.000 0.783 0.217
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.783 0.217
E72.2 Disorders of urea cycle metabolism
0.000 0.783 0.217
E14 Unspecified diabetes mellitus
0.000 0.784 0.216
L75 Apocrine sweat disorders
0.000 0.784 0.216
L74 Eccrine sweat disorders
0.000 0.784 0.216
L67 Hair colour and hair shaft abnormalities
0.000 0.784 0.216
L64 Androgenic alopecia
0.000 0.784 0.216
L62 Nail disorders in diseases classified elsewhere
0.000 0.784 0.216
E56 Other vitamin deficiencies
0.000 0.785 0.215
E72.0 Disorders of amino-acid transport
0.000 0.785 0.215
L13.9 Bullous disorder, unspecified
0.000 0.786 0.214
L13.8 Other specified bullous disorders
0.000 0.786 0.214
L13.1 Subcorneal pustular dermatitis
0.000 0.786 0.214
E74.0 Glycogen storage disease
0.000 0.786 0.213
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.786 0.213
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.786 0.213
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.786 0.213
E74.2 Disorders of galactose metabolism
0.000 0.786 0.213
E74.1 Disorders of fructose metabolism
0.000 0.786 0.213
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.790 0.209
E50 Vitamin A deficiency
0.000 0.790 0.209
E60 Dietary zinc deficiency
0.000 0.790 0.209
E59 Dietary selenium deficiency
0.000 0.790 0.209
E52 Niacin deficiency [pellagra]
0.000 0.790 0.209
E80.2 Other porphyria
0.000 0.792 0.208
L60.9 Nail disorder, unspecified
0.000 0.792 0.208
E73.8 Other lactose intolerance
0.000 0.795 0.205
E73.1 Secondary lactase deficiency
0.000 0.795 0.205
E73.0 Congenital lactase deficiency
0.000 0.795 0.205
L70 Acne
0.000 0.795 0.205
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.798 0.202
E63 Other nutritional deficiencies
0.000 0.799 0.200
E83.9 Disorder of mineral metabolism, unspecified
0.055 0.803 0.142
E83.8 Other disorders of mineral metabolism
0.055 0.803 0.142
E83.2 Disorders of zinc metabolism
0.055 0.803 0.142
E83.0 Disorders of copper metabolism
0.055 0.803 0.142
L65 Other nonscarring hair loss
0.000 0.804 0.196
L71.1 Rhinophyma
0.000 0.806 0.194
E85.4 Organ-limited amyloidosis
0.000 0.809 0.191
E03.5 Myxoedema coma
0.000 0.809 0.191
E03.4 Atrophy of thyroid (acquired)
0.000 0.809 0.191
E03.3 Postinfectious hypothyroidism
0.000 0.809 0.191
L68.0 Hirsutism
0.000 0.809 0.191
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.810 0.190
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.810 0.190

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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