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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2621332
log Bayes Factor = 29.6702
Chromosome 6   position 32,780,317  (GRCh37) Explore rs2621332 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
E20-E35 Disorders of other endocrine glands
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
C44.6 Skin of upper limb, including shoulder
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
C44.3 Skin of other and unspecified parts of face
0.000 0.002 0.998
L40.9 Psoriasis, unspecified
0.000 0.003 0.997
E05.9 Thyrotoxicosis, unspecified
0.000 0.006 0.994
E23 Hypofunction and other disorders of pituitary gland
0.000 0.013 0.987
L57.0 Actinic keratosis
0.000 0.020 0.980
C44.4 Skin of scalp and neck
0.000 0.023 0.977
E27 Other disorders of adrenal gland
0.000 0.026 0.974
G35-G37 Demyelinating diseases of the central nervous system
0.965 0.035 0.000
G37 Other demyelinating diseases of central nervous system
0.953 0.047 0.000
C44.2 Skin of ear and external auricular canal
0.000 0.054 0.946
E23.7 Disorder of pituitary gland, unspecified
0.000 0.059 0.941
G37.9 Demyelinating disease of central nervous system, unspecified
0.931 0.069 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.069 0.931
E23.6 Other disorders of pituitary gland
0.000 0.073 0.927
E10.9 Without complications
0.000 0.075 0.925
E10.2 With renal complications
0.000 0.081 0.919
E10.5 With peripheral circulatory complications
0.000 0.088 0.912
E10.1 With ketoacidosis
0.000 0.099 0.901
E24 Cushing's syndrome
0.000 0.106 0.894
J45.9 Asthma, unspecified
0.892 0.108 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.874 0.126 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.152 0.848
L40-L45 Papulosquamous disorders
0.000 0.153 0.847
E28 Ovarian dysfunction
0.000 0.153 0.847
E11 Non-insulin-dependent diabetes mellitus
0.000 0.157 0.843
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.169 0.831
L40.1 Generalised pustular psoriasis
0.000 0.171 0.829
L40.3 Pustulosis palmaris et plantaris
0.000 0.171 0.829
E11.3 With ophthalmic complications
0.000 0.179 0.821
J45 Asthma
0.805 0.195 0.000
C44.0 Skin of lip
0.000 0.197 0.803
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.200 0.800
M07.3 Other psoriatic arthropathies
0.000 0.204 0.796
E13 Other specified diabetes mellitus
0.000 0.206 0.794
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.207 0.793
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.207 0.793
E23.0 Hypopituitarism
0.000 0.207 0.793
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.211 0.789
G36 Other acute disseminated demyelination
0.787 0.213 0.000
J45.0 Predominantly allergic asthma
0.782 0.218 0.000
E10.0 With coma
0.000 0.219 0.781
E10.4 With neurological complications
0.000 0.220 0.780
L40.4 Guttate psoriasis
0.000 0.229 0.770
E83.1 Disorders of iron metabolism
0.767 0.233 0.000
E06 Thyroiditis
0.000 0.236 0.764
E29 Testicular dysfunction
0.000 0.245 0.755
L40.0 Psoriasis vulgaris
0.000 0.250 0.750
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.258 0.742
E24.0 Pituitary-dependent Cushing's disease
0.000 0.260 0.740
E26 Hyperaldosteronism
0.000 0.261 0.739
L43 Lichen planus
0.000 0.261 0.739
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.264 0.736
E24.2 Drug-induced Cushing's syndrome
0.000 0.267 0.733
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.268 0.732
E28.2 Polycystic ovarian syndrome
0.000 0.276 0.724
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.279 0.721
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.716
E32 Diseases of thymus
0.000 0.283 0.716
E31 Polyglandular dysfunction
0.000 0.283 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E11.2 With renal complications
0.000 0.286 0.714
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.292 0.708
E23.1 Drug-induced hypopituitarism
0.000 0.292 0.708
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.297 0.703
E65-E68 Obesity and other hyperalimentation
0.000 0.298 0.702
E24.9 Cushing's syndrome, unspecified
0.000 0.299 0.701
E27.5 Adrenomedullary hyperfunction
0.000 0.302 0.698
E27.0 Other adrenocortical overactivity
0.000 0.302 0.698
E27.9 Disorder of adrenal gland, unspecified
0.000 0.309 0.691
G37.5 Concentric sclerosis [Balo]
0.683 0.317 0.000
G37.4 Subacute necrotising myelitis
0.683 0.317 0.000
G37.2 Central pontine myelinolysis
0.683 0.317 0.000
G37.1 Central demyelination of corpus callosum
0.683 0.317 0.000
G37.0 Diffuse sclerosis
0.683 0.317 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.324 0.676
E25 Adrenogenital disorders
0.000 0.327 0.673
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.327 0.673
E11.0 With coma
0.000 0.330 0.670
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.334 0.666
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.335 0.665
E05.8 Other thyrotoxicosis
0.000 0.337 0.663
E27.8 Other specified disorders of adrenal gland
0.000 0.339 0.661
E06.3 Autoimmune thyroiditis
0.000 0.339 0.661
G36.0 Neuromyelitis optica [Devic]
0.659 0.341 0.000
E34 Other endocrine disorders
0.000 0.341 0.659
E10.6 With other specified complications
0.000 0.342 0.658
E40-E46 Malnutrition
0.000 0.349 0.651
E24.8 Other Cushing's syndrome
0.000 0.359 0.641
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.359 0.641
E24.3 Ectopic ACTH syndrome
0.000 0.359 0.641
E24.1 Nelson's syndrome
0.000 0.359 0.641
L43.9 Lichen planus, unspecified
0.000 0.359 0.641
E23.2 Diabetes insipidus
0.000 0.364 0.636
E13.9 Without complications
0.000 0.365 0.635
E28.3 Primary ovarian failure
0.000 0.367 0.633
E65 Localised adiposity
0.000 0.381 0.619
E27.2 Addisonian crisis
0.000 0.385 0.615
J45.8 Mixed asthma
0.615 0.385 0.000
L44 Other papulosquamous disorders
0.000 0.393 0.607
L41 Parapsoriasis
0.000 0.393 0.607
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.393 0.607
E28.9 Ovarian dysfunction, unspecified
0.000 0.393 0.607
E28.8 Other ovarian dysfunction
0.000 0.393 0.607
E28.1 Androgen excess
0.000 0.393 0.607
E28.0 Oestrogen excess
0.000 0.393 0.607
E11.7 With multiple complications
0.000 0.396 0.604
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.396 0.604
J45.1 Nonallergic asthma
0.600 0.400 0.000
E70-E90 Metabolic disorders
0.000 0.402 0.598
L57.5 Actinic granuloma
0.000 0.404 0.596
L57.3 Poikiloderma of Civatte
0.000 0.404 0.596
L57.2 Cutis rhomboidalis nuchae
0.000 0.404 0.596
L57.1 Actinic reticuloid
0.000 0.404 0.596
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.595 0.405 0.000
E20 Hypoparathyroidism
0.000 0.409 0.591
E11.8 With unspecified complications
0.000 0.411 0.589
E11.6 With other specified complications
0.000 0.415 0.585
E10.8 With unspecified complications
0.000 0.415 0.584
E13.3 With ophthalmic complications
0.000 0.416 0.584
E29.1 Testicular hypofunction
0.000 0.420 0.580
L43.8 Other lichen planus
0.000 0.427 0.573
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.429 0.571
M07.38 Other psoriatic arthropathies (Other)
0.000 0.429 0.571
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.429 0.571
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.429 0.571
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.429 0.571
E13.8 With unspecified complications
0.000 0.431 0.569
E13.7 With multiple complications
0.000 0.431 0.569
E13.6 With other specified complications
0.000 0.431 0.569
E13.5 With peripheral circulatory complications
0.000 0.431 0.569
E13.4 With neurological complications
0.000 0.431 0.569
E13.2 With renal complications
0.000 0.431 0.569
E13.1 With ketoacidosis
0.000 0.431 0.569
E13.0 With coma
0.000 0.431 0.569
E21.4 Other specified disorders of parathyroid gland
0.000 0.431 0.568
E21.2 Other hyperparathyroidism
0.000 0.435 0.565
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.435 0.565
G36.9 Acute disseminated demyelination, unspecified
0.564 0.436 0.000
G36.8 Other specified acute disseminated demyelination
0.564 0.436 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.564 0.436 0.000
E06.5 Other chronic thyroiditis
0.000 0.439 0.561
E16 Other disorders of pancreatic internal secretion
0.000 0.443 0.557
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.446 0.554
E26.0 Primary hyperaldosteronism
0.000 0.447 0.553
E22 Hyperfunction of pituitary gland
0.000 0.448 0.552
E04 Other non-toxic goitre
0.000 0.449 0.551
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.451 0.549
E06.4 Drug-induced thyroiditis
0.000 0.452 0.548
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.452 0.548
E06.0 Acute thyroiditis
0.000 0.452 0.548
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.453 0.547
E29.9 Testicular dysfunction, unspecified
0.000 0.459 0.541
E29.8 Other testicular dysfunction
0.000 0.459 0.541
E29.0 Testicular hyperfunction
0.000 0.459 0.541
E34.8 Other specified endocrine disorders
0.000 0.461 0.539
E89.0 Postprocedural hypothyroidism
0.000 0.464 0.536
E15 Nondiabetic hypoglycaemic coma
0.000 0.468 0.532
E06.9 Thyroiditis, unspecified
0.000 0.469 0.531
E26.9 Hyperaldosteronism, unspecified
0.000 0.470 0.530
E26.8 Other hyperaldosteronism
0.000 0.470 0.530
E26.1 Secondary hyperaldosteronism
0.000 0.470 0.530
L43.3 Subacute (active) lichen planus
0.000 0.470 0.529
L43.2 Lichenoid drug reaction
0.000 0.470 0.529
L43.1 Bullous lichen planus
0.000 0.470 0.529
L43.0 Hypertrophic lichen planus
0.000 0.470 0.529
E78.2 Mixed hyperlipidaemia
0.000 0.470 0.530
L55 Sunburn
0.000 0.472 0.528
L40.8 Other psoriasis
0.000 0.476 0.523
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.477 0.523
L42 Pityriasis rosea
0.000 0.485 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E78.5 Hyperlipidaemia, unspecified
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.514
E30.8 Other disorders of puberty
0.000 0.486 0.514
E30.1 Precocious puberty
0.000 0.486 0.514
E30.0 Delayed puberty
0.000 0.486 0.514
E31.9 Polyglandular dysfunction, unspecified
0.000 0.486 0.514
E31.8 Other polyglandular dysfunction
0.000 0.486 0.514
E31.1 Polyglandular hyperfunction
0.000 0.486 0.514
E31.0 Autoimmune polyglandular failure
0.000 0.486 0.514
E32.9 Disease of thymus, unspecified
0.000 0.486 0.514
E32.8 Other diseases of thymus
0.000 0.486 0.514
E32.1 Abscess of thymus
0.000 0.486 0.514
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.514
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.514
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.514
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E11.5 With peripheral circulatory complications
0.000 0.493 0.507
E67 Other hyperalimentation
0.000 0.497 0.503
E68 Sequelae of hyperalimentation
0.000 0.497 0.503
E78.6 Lipoprotein deficiency
0.000 0.498 0.502
E88 Other metabolic disorders
0.000 0.500 0.500
E04.0 Non-toxic diffuse goitre
0.000 0.506 0.494
E21.0 Primary hyperparathyroidism
0.000 0.510 0.490
L58 Radiodermatitis
0.000 0.516 0.484
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.516 0.484
E25.9 Adrenogenital disorder, unspecified
0.000 0.517 0.483
E25.8 Other adrenogenital disorders
0.000 0.517 0.483
E34.5 Androgen resistance syndrome
0.000 0.528 0.472
E34.4 Constitutional tall stature
0.000 0.528 0.472
E34.3 Short stature, not elsewhere classified
0.000 0.528 0.472
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.528 0.472
E34.1 Other hypersecretion of intestinal hormones
0.000 0.528 0.472
E78.1 Pure hyperglyceridaemia
0.000 0.531 0.469
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.533 0.467
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.533 0.467
E45 Retarded development following protein-energy malnutrition
0.000 0.533 0.467
E43 Unspecified severe protein-energy malnutrition
0.000 0.533 0.467
E42 Marasmic kwashiorkor
0.000 0.533 0.467
E41 Nutritional marasmus
0.000 0.533 0.467
E40 Kwashiorkor
0.000 0.533 0.467
L10-L14 Bullous disorders
0.000 0.533 0.466
E79 Disorders of purine and pyrimidine metabolism
0.000 0.535 0.465
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.544 0.456
E11.1 With ketoacidosis
0.000 0.546 0.454
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.560 0.440
E84 Cystic fibrosis
0.000 0.562 0.438
E89.3 Postprocedural hypopituitarism
0.000 0.563 0.436
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.564 0.436
L41.9 Parapsoriasis, unspecified
0.000 0.564 0.435
L41.8 Other parapsoriasis
0.000 0.564 0.435
L41.5 Retiform parapsoriasis
0.000 0.564 0.435
L41.4 Large plaque parapsoriasis
0.000 0.564 0.435
L41.3 Small plaque parapsoriasis
0.000 0.564 0.435
L41.2 Lymphomatoid papulosis
0.000 0.564 0.435
L41.1 Pityriasis lichenoides chronica
0.000 0.564 0.435
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.564 0.435
L44.9 Papulosquamous disorder, unspecified
0.000 0.564 0.435
L44.8 Other specified papulosquamous disorders
0.000 0.564 0.435
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.564 0.435
L44.3 Lichen ruber moniliformis
0.000 0.564 0.435
L44.2 Lichen striatus
0.000 0.564 0.435
L44.1 Lichen nitidus
0.000 0.564 0.435
L44.0 Pityriasis rubra pilaris
0.000 0.564 0.435
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.566 0.434
E07 Other disorders of thyroid
0.000 0.567 0.433
L57.4 Cutis laxa senilis
0.000 0.570 0.430
E77 Disorders of glycoprotein metabolism
0.000 0.571 0.429
E76 Disorders of glycosaminoglycan metabolism
0.000 0.571 0.429
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.571 0.429
E70 Disorders of aromatic amino-acid metabolism
0.000 0.571 0.429
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.571 0.429
E20.1 Pseudohypoparathyroidism
0.000 0.576 0.423
E20.0 Idiopathic hypoparathyroidism
0.000 0.576 0.423
E34.9 Endocrine disorder, unspecified
0.000 0.576 0.423
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.579 0.421
E06.1 Subacute thyroiditis
0.000 0.583 0.417
E88.3 Tumour lysis syndrome
0.000 0.584 0.416
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.584 0.415
E88.8 Other specified metabolic disorders
0.000 0.589 0.411
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.590 0.410
C44.9 Malignant neoplasm of skin, unspecified
0.001 0.593 0.406
E89.4 Postprocedural ovarian failure
0.000 0.595 0.405
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.595 0.405
E89.5 Postprocedural testicular hypofunction
0.000 0.595 0.405
E16.2 Hypoglycaemia, unspecified
0.000 0.597 0.403
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.597 0.402
E46 Unspecified protein-energy malnutrition
0.000 0.599 0.401
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.601 0.399
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.601 0.399
E16.4 Abnormal secretion of gastrin
0.000 0.601 0.399
E16.3 Increased secretion of glucagon
0.000 0.601 0.399
L56.3 Solar urticaria
0.000 0.603 0.397
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.603 0.397
L56.1 Drug photoallergic response
0.000 0.603 0.397
L56.0 Drug phototoxic response
0.000 0.603 0.397
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.604 0.396
E22.8 Other hyperfunction of pituitary gland
0.000 0.604 0.396
E04.8 Other specified non-toxic goitre
0.000 0.605 0.395
E22.1 Hyperprolactinaemia
0.000 0.607 0.393
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.608 0.392
E16.1 Other hypoglycaemia
0.000 0.618 0.382
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.618 0.382
E88.2 Lipomatosis, not elsewhere classified
0.000 0.619 0.381
E20.9 Hypoparathyroidism, unspecified
0.000 0.621 0.379
L55.9 Sunburn, unspecified
0.000 0.621 0.378
L55.8 Other sunburn
0.000 0.621 0.378
L55.2 Sunburn of third degree
0.000 0.621 0.378
L55.1 Sunburn of second degree
0.000 0.621 0.378
L55.0 Sunburn of first degree
0.000 0.621 0.378
E89.1 Postprocedural hypoinsulinaemia
0.000 0.622 0.378
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.625 0.375
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.625 0.375
E78.4 Other hyperlipidaemia
0.000 0.626 0.373
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.629 0.371
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.629 0.371
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.630 0.369
E89.2 Postprocedural hypoparathyroidism
0.000 0.632 0.368
E72 Other disorders of amino-acid metabolism
0.000 0.633 0.367
E04.2 Non-toxic multinodular goitre
0.000 0.634 0.366
E78.3 Hyperchylomicronaemia
0.000 0.635 0.365
E67.8 Other specified hyperalimentation
0.000 0.639 0.361
E67.3 Hypervitaminosis D
0.000 0.639 0.361
E67.2 Megavitamin-B6 syndrome
0.000 0.639 0.361
E67.1 Hypercarotenaemia
0.000 0.639 0.361
E67.0 Hypervitaminosis A
0.000 0.639 0.361
E20.8 Other hypoparathyroidism
0.000 0.640 0.359
L56.4 Polymorphous light eruption
0.000 0.641 0.359
E34.0 Carcinoid syndrome
0.000 0.642 0.358
E74 Other disorders of carbohydrate metabolism
0.000 0.642 0.358
E73 Lactose intolerance
0.000 0.642 0.357
L12 Pemphigoid
0.000 0.652 0.348
L58.1 Chronic radiodermatitis
0.000 0.653 0.347
L58.0 Acute radiodermatitis
0.000 0.653 0.347
E88.9 Metabolic disorder, unspecified
0.000 0.653 0.346
E78.8 Other disorders of lipoprotein metabolism
0.000 0.656 0.344
E80.4 Gilbert's syndrome
0.000 0.661 0.339
E85 Amyloidosis
0.000 0.663 0.336
E44.1 Mild protein-energy malnutrition
0.000 0.665 0.335
E44.0 Moderate protein-energy malnutrition
0.000 0.665 0.335
L10 Pemphigus
0.000 0.665 0.334
L14 Bullous disorders in diseases classified elsewhere
0.000 0.665 0.334
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.667 0.333
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.667 0.333
E79.1 Lesch-Nyhan syndrome
0.000 0.667 0.333
E50-E64 Other nutritional deficiencies
0.000 0.669 0.331
L11 Other acantholytic disorders
0.000 0.669 0.331
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.670 0.330
E84.9 Cystic fibrosis, unspecified
0.000 0.676 0.324
E11.4 With neurological complications
0.000 0.682 0.318
E80.6 Other disorders of bilirubin metabolism
0.000 0.684 0.316
E04.9 Non-toxic goitre, unspecified
0.000 0.684 0.316
E84.8 Cystic fibrosis with other manifestations
0.000 0.685 0.314
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.685 0.314
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.685 0.314
E07.1 Dyshormogenetic goitre
0.000 0.689 0.311
E07.0 Hypersecretion of calcitonin
0.000 0.689 0.311
E11.9 Without complications
0.000 0.689 0.311
C44.5 Skin of trunk
0.000 0.690 0.310
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.692 0.307
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.692 0.307
E70.3 Albinism
0.000 0.692 0.307
E70.2 Disorders of tyrosine metabolism
0.000 0.692 0.307
E70.1 Other hyperphenylalaninaemias
0.000 0.692 0.307
E70.0 Classical phenylketonuria
0.000 0.692 0.307
E71.3 Disorders of fatty-acid metabolism
0.000 0.692 0.307
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.692 0.307
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.692 0.307
E71.0 Maple-syrup-urine disease
0.000 0.692 0.307
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.692 0.307
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.692 0.307
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.692 0.307
E76.2 Other mucopolysaccharidoses
0.000 0.692 0.307
E76.1 Mucopolysaccharidosis, type II
0.000 0.692 0.307
E76.0 Mucopolysaccharidosis, type I
0.000 0.692 0.307
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.692 0.307
E77.8 Other disorders of glycoprotein metabolism
0.000 0.692 0.307
E77.1 Defects in glycoprotein degradation
0.000 0.692 0.307
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.692 0.307
L13 Other bullous disorders
0.000 0.693 0.307
L58.9 Radiodermatitis, unspecified
0.000 0.696 0.303
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.698 0.302
E80.5 Crigler-Najjar syndrome
0.000 0.698 0.302
E80.3 Defects of catalase and peroxydase
0.000 0.698 0.302
E80.0 Hereditary erythropoietic porphyria
0.000 0.698 0.302
M07 Psoriatic and enteropathic arthropathies
0.000 0.698 0.302
L60-L75 Disorders of skin appendages
0.000 0.699 0.301
E75.6 Lipid storage disorder, unspecified
0.000 0.706 0.294
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.706 0.294
E75.3 Sphingolipidosis, unspecified
0.000 0.706 0.294
E75.1 Other gangliosidosis
0.000 0.706 0.294
E75.0 GM2 gangliosidosis
0.000 0.706 0.294
E75.2 Other sphingolipidosis
0.000 0.712 0.288
E80.1 Porphyria cutanea tarda
0.000 0.717 0.283
E03 Other hypothyroidism
0.000 0.717 0.283
E75.5 Other lipid storage disorders
0.000 0.718 0.282
E22.0 Acromegaly and pituitary gigantism
0.000 0.720 0.280
E07.8 Other specified disorders of thyroid
0.000 0.721 0.279
L12.9 Pemphigoid, unspecified
0.000 0.734 0.266
E51 Thiamine deficiency
0.000 0.736 0.264
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.737 0.263
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.737 0.263
E72.5 Disorders of glycine metabolism
0.000 0.737 0.263
E72.4 Disorders of ornithine metabolism
0.000 0.737 0.263
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.737 0.263
E72.2 Disorders of urea cycle metabolism
0.000 0.737 0.263
L71 Rosacea
0.000 0.738 0.262
E72.0 Disorders of amino-acid transport
0.000 0.741 0.258
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.743 0.257
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.743 0.257
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.743 0.257
E74.2 Disorders of galactose metabolism
0.000 0.743 0.257
E74.1 Disorders of fructose metabolism
0.000 0.743 0.257
E73.8 Other lactose intolerance
0.000 0.743 0.256
E73.1 Secondary lactase deficiency
0.000 0.743 0.256
E73.0 Congenital lactase deficiency
0.000 0.743 0.256
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.744 0.256
E74.0 Glycogen storage disease
0.000 0.746 0.254
L12.8 Other pemphigoid
0.000 0.750 0.249
L12.3 Acquired epidermolysis bullosa
0.000 0.750 0.249
L12.2 Chronic bullous disease of childhood
0.000 0.750 0.249
E78.0 Pure hypercholesterolaemia
0.000 0.751 0.249
E56 Other vitamin deficiencies
0.000 0.751 0.249
L12.1 Cicatricial pemphigoid
0.000 0.751 0.249
E85.4 Organ-limited amyloidosis
0.000 0.751 0.248
L12.0 Bullous pemphigoid
0.000 0.753 0.247
E83 Disorders of mineral metabolism
0.077 0.757 0.167
E80.2 Other porphyria
0.000 0.758 0.242
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.758 0.241
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.758 0.241
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.758 0.241
L10.9 Pemphigus, unspecified
0.000 0.760 0.240
L10.8 Other pemphigus
0.000 0.760 0.240
L10.5 Drug-induced pemphigus
0.000 0.760 0.240
L10.4 Pemphigus erythematosus
0.000 0.760 0.240
L10.3 Brazilian pemphigus [fogo selvagem]
0.000 0.760 0.240
L10.2 Pemphigus foliaceus
0.000 0.760 0.240
L10.1 Pemphigus vegetans
0.000 0.760 0.240
L10.0 Pemphigus vulgaris
0.000 0.760 0.240
L68 Hypertrichosis
0.000 0.760 0.240
L11.0 Acquired keratosis follicularis
0.000 0.761 0.239
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.762 0.238
E50 Vitamin A deficiency
0.000 0.762 0.238
E60 Dietary zinc deficiency
0.000 0.762 0.238
E59 Dietary selenium deficiency
0.000 0.762 0.238
E52 Niacin deficiency [pellagra]
0.000 0.762 0.238
L11.9 Acantholytic disorder, unspecified
0.000 0.763 0.237
L11.8 Other specified acantholytic disorders
0.000 0.763 0.237
E85.9 Amyloidosis, unspecified
0.000 0.765 0.235
L11.1 Transient acantholytic dermatosis [Grover]
0.000 0.768 0.232
L50-L54 Urticaria and erythema
0.000 0.769 0.231
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.771 0.229
L71.9 Rosacea, unspecified
0.000 0.772 0.228
E63 Other nutritional deficiencies
0.000 0.774 0.226
E55 Vitamin D deficiency
0.000 0.778 0.222
L13.9 Bullous disorder, unspecified
0.000 0.780 0.220
L13.8 Other specified bullous disorders
0.000 0.780 0.220
L13.1 Subcorneal pustular dermatitis
0.000 0.780 0.220
L63 Alopecia areata
0.000 0.780 0.220
M07.5 Arthropathy in ulcerative colitis
0.000 0.783 0.216
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.783 0.216
M07.2 Psoriatic spondylitis
0.000 0.783 0.216
M07.1 Arthritis mutilans
0.000 0.783 0.216
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.783 0.216
L60 Nail disorders
0.000 0.784 0.216
L75 Apocrine sweat disorders
0.000 0.784 0.216
L74 Eccrine sweat disorders
0.000 0.784 0.216
L67 Hair colour and hair shaft abnormalities
0.000 0.784 0.216
L64 Androgenic alopecia
0.000 0.784 0.216
L62 Nail disorders in diseases classified elsewhere
0.000 0.784 0.216
E51.2 Wernicke's encephalopathy
0.000 0.784 0.216
E54 Ascorbic acid deficiency
0.000 0.786 0.214
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.791 0.208
E58 Dietary calcium deficiency
0.000 0.792 0.208
E85.8 Other amyloidosis
0.000 0.795 0.205
L60.9 Nail disorder, unspecified
0.000 0.796 0.204
E03.5 Myxoedema coma
0.000 0.797 0.203
E03.4 Atrophy of thyroid (acquired)
0.000 0.797 0.203
E03.3 Postinfectious hypothyroidism
0.000 0.797 0.203
M07.6 Other enteropathic arthropathies
0.000 0.799 0.200
L70 Acne
0.000 0.800 0.200
E85.3 Secondary systemic amyloidosis
0.000 0.801 0.199
L71.1 Rhinophyma
0.000 0.801 0.199
E03.1 Congenital hypothyroidism without goitre
0.000 0.802 0.198
L68.0 Hirsutism
0.000 0.804 0.196
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.804 0.196
E03.8 Other specified hypothyroidism
0.000 0.808 0.192
L13.0 Dermatitis herpetiformis
0.000 0.808 0.192

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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