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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2647015
log Bayes Factor = 51.8138
Chromosome 6   position 32,664,093  (GRCh37) Explore rs2647015 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.001 0.999
E03.9 Hypothyroidism, unspecified
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
M20-M25 Other joint disorders
0.000 0.001 0.999
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.002 0.998
M05 Seropositive rheumatoid arthritis
0.000 0.004 0.996
H04 Disorders of lachrymal system
0.000 0.005 0.995
E10.1 With ketoacidosis
0.000 0.005 0.995
Chapter X Diseases of the respiratory system
0.000 0.005 0.995
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.007 0.993
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.009 0.991
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.009 0.991
H02 Other disorders of eyelid
0.000 0.009 0.991
J20-J22 Other acute lower respiratory infections
0.000 0.011 0.989
L20-L30 Dermatitis and eczema
0.000 0.013 0.987
J22 Unspecified acute lower respiratory infection
0.000 0.016 0.984
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.017 0.983
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.018 0.982
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.019 0.981
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.021 0.979
N48 Other disorders of penis
0.979 0.021 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.023 0.977
N48.6 Balanitis xerotica obliterans
0.975 0.025 0.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.025 0.975
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.029 0.971
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.035 0.965
H02.1 Ectropion of eyelid
0.000 0.037 0.963
N40-N51 Diseases of male genital organs
0.963 0.037 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.959 0.041 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.041 0.959
H02.0 Entropion and trichiasis of eyelid
0.000 0.043 0.957
E27 Other disorders of adrenal gland
0.000 0.053 0.947
J80 Adult respiratory distress syndrome
0.000 0.055 0.945
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.062 0.938
D50-D53 Nutritional anaemias
0.000 0.065 0.935
L30 Other dermatitis
0.000 0.066 0.934
E27.1 Primary adrenocortical insufficiency
0.000 0.068 0.932
L98.8 Other specified disorders of skin and subcutaneous tissue
0.000 0.070 0.930
N48.8 Other specified disorders of penis
0.925 0.075 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.075 0.925
Chapter V Mental and behavioural disorders
0.000 0.080 0.920
D68 Other coagulation defects
0.000 0.081 0.919
E10.5 With peripheral circulatory complications
0.000 0.084 0.916
M34 Systemic sclerosis
0.000 0.086 0.914
J95-J99 Other diseases of the respiratory system
0.000 0.088 0.912
E06 Thyroiditis
0.000 0.096 0.904
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.096 0.904
N48.0 Leukoplakia of penis
0.902 0.098 0.000
N45 Orchitis and epididymitis
0.901 0.099 0.000
L81 Other disorders of pigmentation
0.000 0.100 0.900
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.101 0.899
M06.0 Seronegative rheumatoid arthritis
0.000 0.101 0.899
F30-F39 Mood [affective] disorders
0.000 0.101 0.899
E10.4 With neurological complications
0.000 0.102 0.898
J00-J06 Acute upper respiratory infections
0.000 0.102 0.898
Chapter I Certain infectious and parasitic diseases
0.000 0.105 0.895
L30.9 Dermatitis, unspecified
0.000 0.108 0.892
H05 Disorders of orbit
0.000 0.111 0.889
H04.2 Epiphora
0.000 0.118 0.882
J84 Other interstitial pulmonary diseases
0.000 0.118 0.882
L98.4 Chronic ulcer of skin, not elsewhere classified
0.000 0.119 0.881
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.123 0.877
L98.0 Pyogenic granuloma
0.000 0.124 0.876
D50 Iron deficiency anaemia
0.000 0.125 0.875
E10.2 With renal complications
0.000 0.125 0.875
L27 Dermatitis due to substances taken internally
0.000 0.126 0.874
E70-E90 Metabolic disorders
0.000 0.129 0.871
L29 Pruritus
0.000 0.129 0.871
H53-H54 Visual disturbances and blindness
0.000 0.130 0.870
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.131 0.869
J00 Acute nasopharyngitis [common cold]
0.000 0.131 0.869
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.132 0.868
B35-B49 Mycoses
0.000 0.134 0.866
B37 Candidiasis
0.000 0.138 0.862
E28 Ovarian dysfunction
0.000 0.140 0.860
F31 Bipolar affective disorder
0.000 0.140 0.860
M31 Other necrotising vasculopathies
0.000 0.140 0.860
N48.9 Disorder of penis, unspecified
0.860 0.140 0.000
L81.4 Other melanin hyperpigmentation
0.000 0.141 0.859
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.859 0.141 0.000
B37.8 Candidiasis of other sites
0.000 0.142 0.858
M60-M63 Disorders of muscles
0.000 0.142 0.858
E11 Non-insulin-dependent diabetes mellitus
0.000 0.149 0.851
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.152 0.848
E11.3 With ophthalmic complications
0.000 0.160 0.840
M06.3 Rheumatoid nodule
0.000 0.161 0.839
D68.5 Primary Thrombophilia
0.000 0.161 0.839
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.165 0.835
E06.3 Autoimmune thyroiditis
0.000 0.166 0.834
M34.9 Systemic sclerosis, unspecified
0.000 0.171 0.829
N48.4 Impotence of organic origin
0.828 0.172 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.172 0.828
H55-H59 Other disorders of eye and adnexa
0.000 0.175 0.825
L83 Acanthosis nigricans
0.000 0.176 0.824
D50.8 Other iron deficiency anaemias
0.000 0.178 0.822
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.178 0.822
H04.8 Other disorders of lachrymal system
0.000 0.178 0.822
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.180 0.820
H53 Visual disturbances
0.000 0.182 0.818
F32 Depressive episode
0.000 0.182 0.818
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.185 0.815
M35.1 Other overlap syndromes
0.000 0.185 0.815
L94 Other localised connective tissue disorders
0.000 0.188 0.812
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.188 0.812
D52 Folate deficiency anaemia
0.000 0.191 0.809
J98 Other respiratory disorders
0.000 0.194 0.806
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.195 0.805
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.199 0.801
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.201 0.799
E27.8 Other specified disorders of adrenal gland
0.000 0.206 0.794
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.206 0.794
L29.0 Pruritus ani
0.000 0.206 0.794
B37.0 Candidal stomatitis
0.000 0.208 0.792
D68.9 Coagulation defect, unspecified
0.000 0.208 0.792
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.209 0.791
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.210 0.790
L93 Lupus erythematosus
0.000 0.210 0.790
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.788 0.212 0.000
D60-D64 Aplastic and other anaemias
0.000 0.212 0.788
N48.5 Ulcer of penis
0.784 0.216 0.000
J81 Pulmonary oedema
0.000 0.218 0.782
H53.9 Visual disturbance, unspecified
0.000 0.220 0.780
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.223 0.777
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.224 0.776
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.225 0.775
F32.2 Severe depressive episode without psychotic symptoms
0.000 0.226 0.774
L85 Other epidermal thickening
0.000 0.226 0.773
N44 Torsion of testis
0.773 0.227 0.000
J20 Acute bronchitis
0.000 0.227 0.773
H02.6 Xanthelasma of eyelid
0.000 0.228 0.772
D68.0 Von Willebrand's disease
0.000 0.228 0.772
M31.3 Wegener's granulomatosis
0.000 0.230 0.770
L08 Other local infections of skin and subcutaneous tissue
0.000 0.230 0.770
N41 Inflammatory diseases of prostate
0.769 0.231 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.231 0.768
F20 Schizophrenia
0.000 0.232 0.768
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.234 0.766
L80 Vitiligo
0.000 0.234 0.766
A63.0 Anogenital (venereal) warts
0.000 0.235 0.765
M62 Other disorders of muscle
0.000 0.235 0.764
F32.1 Moderate depressive episode
0.000 0.236 0.764
M32 Systemic lupus erythematosus
0.000 0.237 0.763
H04.4 Chronic inflammation of lachrymal passages
0.000 0.239 0.761
L30.8 Other specified dermatitis
0.000 0.241 0.759
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.242 0.758
E28.2 Polycystic ovarian syndrome
0.000 0.242 0.758
H05.2 Exophthalmic conditions
0.000 0.243 0.757
D61 Other aplastic anaemias
0.000 0.247 0.753
D68.8 Other specified coagulation defects
0.000 0.247 0.753
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.247 0.753
L57.0 Actinic keratosis
0.000 0.249 0.751
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.252 0.748
L20 Atopic dermatitis
0.000 0.253 0.747
E10.6 With other specified complications
0.000 0.254 0.746
H05.0 Acute inflammation of orbit
0.000 0.255 0.745
H02.9 Disorder of eyelid, unspecified
0.000 0.257 0.743
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.257 0.743
B07 Viral warts
0.000 0.257 0.743
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.260 0.740
E50-E64 Other nutritional deficiencies
0.000 0.262 0.738
E89.0 Postprocedural hypothyroidism
0.000 0.264 0.736
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.265 0.735
M35.7 Hypermobility syndrome
0.000 0.266 0.734
E29 Testicular dysfunction
0.000 0.270 0.730
E07 Other disorders of thyroid
0.000 0.270 0.730
D61.9 Aplastic anaemia, unspecified
0.000 0.271 0.729
M34.1 CR(E)ST syndrome
0.000 0.271 0.728
H02.4 Ptosis of eyelid
0.000 0.272 0.728
E04 Other non-toxic goitre
0.000 0.274 0.726
M06.34 Rheumatoid nodule (Hand)
0.000 0.276 0.724
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.276 0.724
H04.9 Disorder of lachrymal system, unspecified
0.000 0.276 0.724
E27.9 Disorder of adrenal gland, unspecified
0.000 0.276 0.724
F22 Persistent delusional disorders
0.000 0.277 0.723
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.278 0.722
F31.9 Bipolar affective disorder, unspecified
0.000 0.278 0.722
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.279 0.721
D52.9 Folate deficiency anaemia, unspecified
0.000 0.281 0.719
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.281 0.719
J98.4 Other disorders of lung
0.000 0.282 0.718
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M12 Other specific arthropathies
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.8 Other specified systemic involvement of connective tissue
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
M35.2 Behcet's disease
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.716
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H30 Chorioretinal inflammation
0.000 0.284 0.716
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.284 0.716
H01 Other inflammation of eyelid
0.000 0.284 0.716
E05.8 Other thyrotoxicosis
0.000 0.285 0.715
H55 Nystagmus and other irregular eye movements
0.000 0.285 0.715
D68.6 Other Thrombophilia
0.000 0.286 0.714
M05.8 Other seropositive rheumatoid arthritis
0.000 0.286 0.714
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.286 0.714
M05.2 Rheumatoid vasculitis
0.000 0.286 0.714
M05.1 Rheumatoid lung disease
0.000 0.286 0.714
M05.0 Felty's syndrome
0.000 0.286 0.714
H04.6 Other changes in lachrymal passages
0.000 0.286 0.714
H04.0 Dacryoadenitis
0.000 0.286 0.714
M62.8 Other specified disorders of muscle
0.000 0.288 0.712
H53.0 Amblyopia ex anopsia
0.000 0.288 0.712
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.288 0.712
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.288 0.712
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.288 0.712
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.288 0.712
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.288 0.712
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.288 0.712
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.288 0.712
M21 Other acquired deformities of limbs
0.000 0.289 0.710
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.290 0.710
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.290 0.710
M07 Psoriatic and enteropathic arthropathies
0.000 0.290 0.710
E87.7 Fluid overload
0.000 0.291 0.709
L25 Unspecified contact dermatitis
0.000 0.292 0.708
L24 Irritant contact dermatitis
0.000 0.292 0.708
L21 Seborrhoeic dermatitis
0.000 0.292 0.708
L26 Exfoliative dermatitis
0.000 0.292 0.708
L22 Diaper [napkin] dermatitis
0.000 0.292 0.708
E11.1 With ketoacidosis
0.000 0.293 0.707
L05 Pilonidal cyst
0.000 0.293 0.707
L28 Lichen simplex chronicus and prurigo
0.000 0.293 0.707
F30 Manic episode
0.000 0.294 0.706
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.000 0.295 0.705
H06.2 Dysthyroid exophthalmos
0.000 0.295 0.705
E88 Other metabolic disorders
0.000 0.296 0.704
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.298 0.702
L87 Transepidermal elimination disorders
0.000 0.298 0.702
L88 Pyoderma gangrenosum
0.000 0.298 0.702
L86 Keratoderma in diseases classified elsewhere
0.000 0.298 0.702
N48.3 Priapism
0.702 0.298 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.299 0.701
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.302 0.698
N48.1 Balanoposthitis
0.698 0.302 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.000 0.303 0.697
L98.7 Excessive and redundant skin and subcutaneous tissue
0.000 0.304 0.696
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.000 0.304 0.696
L98.5 Mucinosis of skin
0.000 0.304 0.696
L98.3 Eosinophilic cellulitis [Wells]
0.000 0.304 0.696
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.000 0.304 0.696
L98.1 Factitial dermatitis
0.000 0.304 0.696
J95.0 Tracheostomy malfunction
0.000 0.304 0.696
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.305 0.695
E27.2 Addisonian crisis
0.000 0.306 0.694
E16 Other disorders of pancreatic internal secretion
0.000 0.306 0.694
J21 Acute bronchiolitis
0.000 0.306 0.694
F34 Persistent mood [affective] disorders
0.000 0.306 0.694
E28.3 Primary ovarian failure
0.000 0.307 0.693
F23 Acute and transient psychotic disorders
0.000 0.309 0.691
L23 Allergic contact dermatitis
0.000 0.309 0.690
N51 Disorders of male genital organs in diseases classified elsewhere
0.690 0.310 0.000
H02.2 Lagophthalmos
0.000 0.310 0.690
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.312 0.688
E32 Diseases of thymus
0.000 0.312 0.688
E31 Polyglandular dysfunction
0.000 0.312 0.688
E30 Disorders of puberty, not elsewhere classified
0.000 0.312 0.688
E20 Hypoparathyroidism
0.000 0.312 0.688
J01 Acute sinusitis
0.000 0.317 0.683
D69 Purpura and other haemorrhagic conditions
0.000 0.317 0.683
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.317 0.683
N46 Male infertility
0.682 0.317 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.318 0.682
F80-F89 Disorders of psychological development
0.000 0.319 0.681
M06.4 Inflammatory polyarthropathy
0.000 0.321 0.679
E27.5 Adrenomedullary hyperfunction
0.000 0.321 0.679
E27.0 Other adrenocortical overactivity
0.000 0.321 0.679
J04 Acute laryngitis and tracheitis
0.000 0.322 0.678
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.322 0.678
J98.9 Respiratory disorder, unspecified
0.000 0.323 0.677
F39 Unspecified mood [affective] disorder
0.000 0.323 0.677
D51 Vitamin B12 deficiency anaemia
0.000 0.324 0.676
G35 Multiple sclerosis
0.000 0.324 0.676
E86 Volume depletion
0.000 0.326 0.674
E73 Lactose intolerance
0.000 0.326 0.674
D67 Hereditary factor IX deficiency
0.000 0.327 0.673
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.327 0.673
L30.5 Pityriasis alba
0.000 0.330 0.669
L30.4 Erythema intertrigo
0.000 0.330 0.669
L30.2 Cutaneous autosensitisation
0.000 0.330 0.669
L30.1 Dyshidrosis [pompholyx]
0.000 0.330 0.669
L30.0 Nummular dermatitis
0.000 0.330 0.669
F20.0 Paranoid schizophrenia
0.000 0.332 0.668
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.334 0.666
M21.0 Valgus deformity, not elsewhere classified
0.000 0.336 0.664
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.337 0.663
L58 Radiodermatitis
0.000 0.337 0.663
L55 Sunburn
0.000 0.337 0.663
N49.2 Inflammatory disorders of scrotum
0.663 0.337 0.000
E03.8 Other specified hypothyroidism
0.000 0.338 0.662
E14 Unspecified diabetes mellitus
0.000 0.339 0.661
H57 Other disorders of eye and adnexa
0.000 0.339 0.661
E26 Hyperaldosteronism
0.000 0.340 0.660
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.340 0.660
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.341 0.659
D68.4 Acquired coagulation factor deficiency
0.000 0.341 0.659
D68.1 Hereditary factor XI deficiency
0.000 0.341 0.659
D68.2 Hereditary deficiency of other clotting factors
0.000 0.342 0.657
F29 Unspecified nonorganic psychosis
0.000 0.343 0.657
J84.8 Other specified interstitial pulmonary diseases
0.000 0.343 0.657
M00-M03 Infectious arthropathies
0.000 0.343 0.656
H16 Keratitis
0.000 0.344 0.656
B37.9 Candidiasis, unspecified
0.000 0.345 0.655
M34.8 Other forms of systemic sclerosis
0.000 0.345 0.655
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.345 0.655
M34.0 Progressive systemic sclerosis
0.000 0.345 0.655
L93.0 Discoid lupus erythematosus
0.000 0.346 0.654
J96 Respiratory failure, not elsewhere classified
0.000 0.346 0.654
M65-M68 Disorders of synovium and tendon
0.000 0.346 0.654
N41.0 Acute prostatitis
0.652 0.348 0.000
H02.5 Other disorders affecting eyelid function
0.000 0.349 0.651
E06.9 Thyroiditis, unspecified
0.000 0.349 0.651
B25-B34 Other viral diseases
0.000 0.350 0.650
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.351 0.649
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.351 0.649
D53 Other nutritional anaemias
0.000 0.351 0.649
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.351 0.649
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.351 0.648
L29.9 Pruritus, unspecified
0.000 0.352 0.648
E06.5 Other chronic thyroiditis
0.000 0.352 0.648
E06.4 Drug-induced thyroiditis
0.000 0.352 0.648
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.352 0.648
E06.1 Subacute thyroiditis
0.000 0.352 0.648
E06.0 Acute thyroiditis
0.000 0.352 0.648
L01 Impetigo
0.000 0.352 0.648
L00 Staphylococcal scalded skin syndrome
0.000 0.352 0.648
L94.0 Localised scleroderma [morphea]
0.000 0.352 0.647
M30 Polyarteritis nodosa and related conditions
0.000 0.353 0.647
F70-F79 Mental retardation
0.000 0.353 0.646
M62.80 Other specified disorders of muscle (Multiple sites)
0.000 0.354 0.646
L94.2 Calcinosis cutis
0.000 0.355 0.645
L81.7 Pigmented purpuric dermatosis
0.000 0.355 0.645
L81.6 Other disorders of diminished melanin formation
0.000 0.355 0.645
L81.5 Leukoderma, not elsewhere classified
0.000 0.355 0.645
L81.3 Cafe au lait spots
0.000 0.355 0.645
L81.2 Freckles
0.000 0.355 0.645
L81.1 Chloasma
0.000 0.355 0.645
L81.0 Postinflammatory hyperpigmentation
0.000 0.355 0.645
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.355 0.645
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.355 0.645
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.355 0.645
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.355 0.645
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.355 0.645
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.355 0.645
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.355 0.645
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.355 0.645
J95.8 Other postprocedural respiratory disorders
0.000 0.356 0.644
F38 Other mood [affective] disorders
0.000 0.356 0.644
E16.2 Hypoglycaemia, unspecified
0.000 0.356 0.644
M11 Other crystal arthropathies
0.000 0.356 0.644
N50 Other disorders of male genital organs
0.642 0.357 0.000
M22 Disorders of patella
0.000 0.358 0.642
N48.2 Other inflammatory disorders of penis
0.642 0.358 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.358 0.642
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.358 0.642
A75-A79 Rickettsioses
0.000 0.358 0.642
A70-A74 Other diseases caused by chlamydiae
0.000 0.358 0.642
A20-A28 Certain zoonotic bacterial diseases
0.000 0.358 0.642
H53.2 Diplopia
0.000 0.360 0.640
M14 Arthropathies in other diseases classified elsewhere
0.000 0.360 0.640
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.361 0.639
L81.8 Other specified disorders of pigmentation
0.000 0.362 0.638
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.637 0.362 0.000
H05.9 Disorder of orbit, unspecified
0.000 0.363 0.637
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.000 0.363 0.637
H05.4 Enophthalmos
0.000 0.363 0.637
H05.3 Deformity of orbit
0.000 0.363 0.637
H05.1 Chronic inflammatory disorders of orbit
0.000 0.363 0.637
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.363 0.637
C44 Other malignant neoplasms of skin
0.000 0.363 0.637
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.364 0.636
L84 Corns and callosities
0.000 0.365 0.635
E23 Hypofunction and other disorders of pituitary gland
0.000 0.366 0.634
J02 Acute pharyngitis
0.000 0.366 0.634
J20.9 Acute bronchitis, unspecified
0.000 0.367 0.633
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.000 0.367 0.633
Chapter VI Diseases of the nervous system
0.000 0.367 0.633
J84.0 Alveolar and parietoalveolar conditions
0.000 0.367 0.632
E11.2 With renal complications
0.000 0.369 0.631
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.371 0.629
L57.5 Actinic granuloma
0.000 0.371 0.629
L57.3 Poikiloderma of Civatte
0.000 0.371 0.629
L57.2 Cutis rhomboidalis nuchae
0.000 0.371 0.629
L57.1 Actinic reticuloid
0.000 0.371 0.629
B50-B64 Protozoal diseases
0.000 0.372 0.628
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.372 0.628
D50.1 Sideropenic dysphagia
0.000 0.372 0.628
L10-L14 Bullous disorders
0.000 0.373 0.627
C44.7 Skin of lower limb, including hip
0.000 0.373 0.627
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.373 0.626
L27.8 Dermatitis due to other substances taken internally
0.000 0.373 0.626
L27.2 Dermatitis due to ingested food
0.000 0.373 0.626
F25 Schizoaffective disorders
0.000 0.374 0.626
C44.3 Skin of other and unspecified parts of face
0.000 0.375 0.625
E84 Cystic fibrosis
0.000 0.375 0.625
E79 Disorders of purine and pyrimidine metabolism
0.000 0.375 0.625
E77 Disorders of glycoprotein metabolism
0.000 0.375 0.625
E76 Disorders of glycosaminoglycan metabolism
0.000 0.375 0.625
E72 Other disorders of amino-acid metabolism
0.000 0.375 0.625
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.375 0.625
E70 Disorders of aromatic amino-acid metabolism
0.000 0.375 0.625
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.375 0.625
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.375 0.625
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.375 0.624
H05.8 Other disorders of orbit
0.000 0.376 0.624
L29.3 Anogenital pruritus, unspecified
0.000 0.376 0.624
L29.1 Pruritus scroti
0.000 0.376 0.624
F28 Other nonorganic psychotic disorders
0.000 0.377 0.623
F24 Induced delusional disorder
0.000 0.377 0.623
F21 Schizotypal disorder
0.000 0.377 0.623
L85.8 Other specified epidermal thickening
0.000 0.377 0.623
L57.4 Cutis laxa senilis
0.000 0.379 0.621
B48 Other mycoses, not elsewhere classified
0.000 0.379 0.621
B47 Mycetoma
0.000 0.379 0.621
B46 Zygomycosis
0.000 0.379 0.621
B45 Cryptococcosis
0.000 0.379 0.621
B43 Chromomycosis and phaeomycotic abscess
0.000 0.379 0.621
B42 Sporotrichosis
0.000 0.379 0.621
B41 Paracoccidioidomycosis
0.000 0.379 0.621
B40 Blastomycosis
0.000 0.379 0.621
B39 Histoplasmosis
0.000 0.379 0.621
B38 Coccidioidomycosis
0.000 0.379 0.621
F22.0 Delusional disorder
0.000 0.381 0.619
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.000 0.381 0.619
M86-M90 Other osteopathies
0.000 0.381 0.619
B37.7 Candidal septicaemia
0.000 0.382 0.618
B37.6 Candidal endocarditis
0.000 0.382 0.618
B37.5 Candidal meningitis
0.000 0.382 0.618
B37.1 Pulmonary candidiasis
0.000 0.382 0.618
E28.9 Ovarian dysfunction, unspecified
0.000 0.383 0.617
E28.8 Other ovarian dysfunction
0.000 0.383 0.617
E28.1 Androgen excess
0.000 0.383 0.617
E28.0 Oestrogen excess
0.000 0.383 0.617
F31.8 Other bipolar affective disorders
0.000 0.383 0.617
F31.7 Bipolar affective disorder, currently in remission
0.000 0.383 0.617
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.000 0.383 0.617
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.000 0.383 0.617
M31.9 Necrotising vasculopathy, unspecified
0.000 0.383 0.617
M31.8 Other specified necrotising vasculopathies
0.000 0.383 0.617
M31.7 Microscopic polyangiitis
0.000 0.383 0.617
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.383 0.617
M31.2 Lethal midline granuloma
0.000 0.383 0.617
M31.1 Thrombotic microangiopathy
0.000 0.383 0.617
M31.0 Hypersensitivity angiitis
0.000 0.383 0.617
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.383 0.616
M63 Disorders of muscle in diseases classified elsewhere
0.000 0.385 0.615
M61 Calcification and ossification of muscle
0.000 0.385 0.615
E04.0 Non-toxic diffuse goitre
0.000 0.386 0.614
E65-E68 Obesity and other hyperalimentation
0.000 0.386 0.614
B65-B83 Helminthiases
0.000 0.387 0.613
L29.8 Other pruritus
0.000 0.388 0.612
F20.9 Schizophrenia, unspecified
0.000 0.389 0.611
E11.7 With multiple complications
0.000 0.390 0.610
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.390 0.610
D62 Acute posthaemorrhagic anaemia
0.000 0.391 0.609

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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