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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2647087
log Bayes Factor = 113.528
Chromosome 6   position 32,681,049  (GRCh37) Explore rs2647087 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
J47 Bronchiectasis
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.998 0.002 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.002 0.998
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.003 0.997
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.003 0.997
M05-M14 Inflammatory polyarthropathies
0.000 0.004 0.996
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.004 0.996
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.007 0.993
K90.0 Coeliac disease
0.000 0.007 0.993
J20-J22 Other acute lower respiratory infections
0.000 0.016 0.984
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.017 0.983
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.019 0.981
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.020 0.980
E10.5 With peripheral circulatory complications
0.000 0.023 0.977
E05.9 Thyrotoxicosis, unspecified
0.000 0.024 0.976
E10.2 With renal complications
0.000 0.026 0.974
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.027 0.973
J22 Unspecified acute lower respiratory infection
0.000 0.029 0.971
L40.0 Psoriasis vulgaris
0.967 0.033 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.041 0.959
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.041 0.959
E14 Unspecified diabetes mellitus
0.000 0.045 0.955
E16 Other disorders of pancreatic internal secretion
0.000 0.046 0.954
M06.3 Rheumatoid nodule
0.000 0.051 0.949
J81 Pulmonary oedema
0.000 0.052 0.948
J80 Adult respiratory distress syndrome
0.000 0.052 0.948
M06.0 Seronegative rheumatoid arthritis
0.000 0.055 0.945
E16.2 Hypoglycaemia, unspecified
0.000 0.058 0.942
J84 Other interstitial pulmonary diseases
0.000 0.063 0.937
E14.3 With ophthalmic complications
0.000 0.067 0.933
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.075 0.925
M35.1 Other overlap syndromes
0.000 0.079 0.921
E06 Thyroiditis
0.000 0.081 0.919
M06.34 Rheumatoid nodule (Hand)
0.000 0.091 0.909
E04 Other non-toxic goitre
0.000 0.093 0.907
E10.0 With coma
0.000 0.137 0.863
L40.4 Guttate psoriasis
0.860 0.140 0.000
E10.8 With unspecified complications
0.000 0.149 0.851
E06.3 Autoimmune thyroiditis
0.000 0.150 0.850
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.150 0.850
E50-E64 Other nutritional deficiencies
0.000 0.151 0.849
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.156 0.844
J95-J99 Other diseases of the respiratory system
0.000 0.167 0.833
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.171 0.829
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.175 0.825
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.177 0.823
E04.0 Non-toxic diffuse goitre
0.000 0.184 0.816
L40.1 Generalised pustular psoriasis
0.813 0.187 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.189 0.811
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.191 0.809
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.203 0.797
L40.8 Other psoriasis
0.790 0.210 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.213 0.787
M35.2 Behcet's disease
0.000 0.215 0.785
J21 Acute bronchiolitis
0.000 0.222 0.778
J42 Unspecified chronic bronchitis
0.000 0.223 0.777
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.224 0.776
J46 Status asthmaticus
0.000 0.225 0.775
M06.4 Inflammatory polyarthropathy
0.000 0.227 0.773
E07 Other disorders of thyroid
0.000 0.229 0.771
L40.3 Pustulosis palmaris et plantaris
0.765 0.235 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.236 0.764
E10.6 With other specified complications
0.000 0.237 0.763
J84.8 Other specified interstitial pulmonary diseases
0.000 0.249 0.751
E20-E35 Disorders of other endocrine glands
0.000 0.253 0.747
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.253 0.747
J41 Simple and mucopurulent chronic bronchitis
0.000 0.255 0.745
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.264 0.736
E04.9 Non-toxic goitre, unspecified
0.000 0.273 0.727
E05.8 Other thyrotoxicosis
0.000 0.273 0.727
M35.8 Other specified systemic involvement of connective tissue
0.000 0.275 0.725
J00-J06 Acute upper respiratory infections
0.000 0.276 0.724
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.276 0.724
M12 Other specific arthropathies
0.000 0.276 0.724
E61 Deficiency of other nutrient elements
0.000 0.277 0.723
E27 Other disorders of adrenal gland
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.283 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
M05.8 Other seropositive rheumatoid arthritis
0.000 0.285 0.715
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.285 0.715
M05.2 Rheumatoid vasculitis
0.000 0.285 0.715
M05.1 Rheumatoid lung disease
0.000 0.285 0.715
M05.0 Felty's syndrome
0.000 0.285 0.715
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.286 0.714
M08 Juvenile arthritis
0.000 0.286 0.714
E55 Vitamin D deficiency
0.000 0.291 0.709
E27.1 Primary adrenocortical insufficiency
0.000 0.294 0.706
E14.1 With ketoacidosis
0.000 0.298 0.702
E06.9 Thyroiditis, unspecified
0.000 0.299 0.701
E15 Nondiabetic hypoglycaemic coma
0.000 0.303 0.697
E14.5 With peripheral circulatory complications
0.000 0.306 0.694
J20 Acute bronchitis
0.000 0.312 0.688
E14.7 With multiple complications
0.000 0.315 0.685
E14.6 With other specified complications
0.000 0.315 0.685
E14.0 With coma
0.000 0.315 0.685
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.316 0.684
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.316 0.684
E16.4 Abnormal secretion of gastrin
0.000 0.316 0.684
E16.3 Increased secretion of glucagon
0.000 0.316 0.684
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.319 0.680
M06.38 Rheumatoid nodule (Other)
0.000 0.319 0.680
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.319 0.680
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.319 0.680
M06.33 Rheumatoid nodule (Forearm)
0.000 0.319 0.680
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.319 0.680
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.319 0.680
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.320 0.680
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.321 0.679
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.322 0.678
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.322 0.678
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.322 0.678
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.322 0.678
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.322 0.678
J33 Nasal polyp
0.000 0.328 0.672
J84.0 Alveolar and parietoalveolar conditions
0.000 0.328 0.672
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.332 0.668
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.334 0.666
J30-J39 Other diseases of upper respiratory tract
0.000 0.334 0.666
E14.8 With unspecified complications
0.000 0.336 0.664
E14.2 Withrenal complications
0.000 0.336 0.664
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.341 0.659
E06.5 Other chronic thyroiditis
0.000 0.341 0.659
E06.4 Drug-induced thyroiditis
0.000 0.341 0.659
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.341 0.659
E06.1 Subacute thyroiditis
0.000 0.341 0.659
E06.0 Acute thyroiditis
0.000 0.341 0.659
J33.9 Nasal polyp, unspecified
0.000 0.348 0.652
E04.8 Other specified non-toxic goitre
0.000 0.350 0.650
E40-E46 Malnutrition
0.000 0.357 0.643
H36 Retinal disorders in diseases classified elsewhere
0.000 0.360 0.640
E14.4 With neurological complications
0.000 0.362 0.638
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.362 0.638
J33.0 Polyp of nasal cavity
0.000 0.367 0.633
M35.7 Hypermobility syndrome
0.000 0.368 0.632
E14.9 Without complications
0.000 0.369 0.631
J21.9 Acute bronchiolitis, unspecified
0.000 0.370 0.630
M14 Arthropathies in other diseases classified elsewhere
0.000 0.370 0.630
E27.8 Other specified disorders of adrenal gland
0.000 0.373 0.627
J33.8 Other polyp of sinus
0.000 0.380 0.620
E28 Ovarian dysfunction
0.000 0.381 0.619
E07.8 Other specified disorders of thyroid
0.000 0.385 0.615
J00 Acute nasopharyngitis [common cold]
0.000 0.385 0.615
J99.0 Rheumatoid lung disease
0.000 0.388 0.612
M10 Gout
0.000 0.388 0.612
E55.9 Vitamin D deficiency, unspecified
0.000 0.391 0.609
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.391 0.609
E63 Other nutritional deficiencies
0.000 0.391 0.609
E51 Thiamine deficiency
0.000 0.391 0.609
E50 Vitamin A deficiency
0.000 0.391 0.609
E60 Dietary zinc deficiency
0.000 0.391 0.609
E59 Dietary selenium deficiency
0.000 0.391 0.609
E54 Ascorbic acid deficiency
0.000 0.391 0.609
E52 Niacin deficiency [pellagra]
0.000 0.391 0.609
J98 Other respiratory disorders
0.000 0.398 0.602
E53 Deficiency of other B group vitamins
0.000 0.400 0.600
J96 Respiratory failure, not elsewhere classified
0.000 0.402 0.597
E61.1 Iron deficiency
0.000 0.403 0.597
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.406 0.593
E56 Other vitamin deficiencies
0.000 0.409 0.591
J60-J70 Lung diseases due to external agents
0.000 0.416 0.584
E29 Testicular dysfunction
0.000 0.421 0.579
E61.2 Magnesium deficiency
0.000 0.423 0.577
J43 Emphysema
0.000 0.424 0.575
J01 Acute sinusitis
0.000 0.426 0.574
N48 Other disorders of penis
0.572 0.428 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.433 0.567
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.435 0.565
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.438 0.562
J41.0 Simple chronic bronchitis
0.000 0.438 0.562
J98.9 Respiratory disorder, unspecified
0.000 0.438 0.562
E26 Hyperaldosteronism
0.000 0.438 0.561
N48.1 Balanoposthitis
0.560 0.440 0.000
N48.8 Other specified disorders of penis
0.559 0.441 0.000
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.442 0.558
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.442 0.558
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.442 0.558
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.446 0.554
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.446 0.554
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.446 0.554
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.446 0.554
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.446 0.554
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.446 0.554
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.446 0.554
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.446 0.554
M12.3 Palindromic rheumatism
0.000 0.446 0.554
E07.1 Dyshormogenetic goitre
0.000 0.447 0.552
E07.0 Hypersecretion of calcitonin
0.000 0.447 0.552
M11 Other crystal arthropathies
0.000 0.455 0.544
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.457 0.543
J09-J18 Influenza and pneumonia
0.000 0.457 0.543
E34 Other endocrine disorders
0.000 0.457 0.543
E07.9 Disorder of thyroid, unspecified
0.000 0.459 0.541
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.460 0.540
J40 Bronchitis, not specified as acute or chronic
0.000 0.461 0.539
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.464 0.536
E32 Diseases of thymus
0.000 0.464 0.536
E31 Polyglandular dysfunction
0.000 0.464 0.536
E30 Disorders of puberty, not elsewhere classified
0.000 0.464 0.536
N48.6 Balanitis xerotica obliterans
0.536 0.464 0.000
M20-M25 Other joint disorders
0.000 0.464 0.536
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.466 0.534
J41.1 Mucopurulent chronic bronchitis
0.000 0.466 0.534
E58 Dietary calcium deficiency
0.000 0.469 0.531
E16.1 Other hypoglycaemia
0.000 0.470 0.530
M34 Systemic sclerosis
0.000 0.471 0.529
J32 Chronic sinusitis
0.000 0.476 0.524
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.481 0.519
M12.5 Traumatic arthropathy
0.000 0.481 0.519
M12.4 Intermittent hydrarthrosis
0.000 0.481 0.519
M12.1 Kaschin-Beck disease
0.000 0.481 0.519
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.481 0.519
E61.9 Deficiency of nutrient element, unspecified
0.000 0.482 0.518
E61.8 Deficiency of other specified nutrient elements
0.000 0.482 0.518
E61.7 Deficiency of multiple nutrient elements
0.000 0.482 0.518
E61.6 Vanadium deficiency
0.000 0.482 0.518
E61.5 Molybdenum deficiency
0.000 0.482 0.518
E61.4 Chromium deficiency
0.000 0.482 0.518
E61.3 Manganese deficiency
0.000 0.482 0.518
E61.0 Copper deficiency
0.000 0.482 0.518
E28.2 Polycystic ovarian syndrome
0.000 0.482 0.518
E11 Non-insulin-dependent diabetes mellitus
0.000 0.483 0.517
J04 Acute laryngitis and tracheitis
0.000 0.484 0.516
E27.5 Adrenomedullary hyperfunction
0.000 0.485 0.515
E27.0 Other adrenocortical overactivity
0.000 0.485 0.515
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.486 0.514
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.486 0.514
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.486 0.514
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.486 0.514
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.486 0.514
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.486 0.514
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.486 0.514
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.486 0.514
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.486 0.514
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M05.09 Felty's syndrome (Site unspecified)
0.000 0.487 0.513
M05.08 Felty's syndrome (Other)
0.000 0.487 0.513
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.487 0.513
M05.06 Felty's syndrome (Lower leg)
0.000 0.487 0.513
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.487 0.513
M05.04 Felty's syndrome (Hand)
0.000 0.487 0.513
M05.03 Felty's syndrome (Forearm)
0.000 0.487 0.513
M05.02 Felty's syndrome (Upper arm)
0.000 0.487 0.513
M05.01 Felty's syndrome (Shoulder region)
0.000 0.487 0.513
M05.00 Felty's syndrome (Multiple sites)
0.000 0.487 0.513
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.487 0.513
M05.18 Rheumatoid lung disease (Other)
0.000 0.487 0.513
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.487 0.513
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.487 0.513
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.487 0.513
M05.14 Rheumatoid lung disease (Hand)
0.000 0.487 0.513
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.487 0.513
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.487 0.513
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.487 0.513
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.487 0.513
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.487 0.513
M05.28 Rheumatoid vasculitis (Other)
0.000 0.487 0.513
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.487 0.513
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.487 0.513
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.487 0.513
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.487 0.513
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.487 0.513
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.487 0.513
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.487 0.513
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.487 0.513
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.487 0.513
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.487 0.513
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.487 0.513
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.487 0.513
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.487 0.513
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.487 0.513
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.487 0.513
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.487 0.513
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.487 0.513
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.487 0.513
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.487 0.513
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.487 0.513
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.487 0.513
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.487 0.513
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.487 0.513
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.487 0.513
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.487 0.513
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.487 0.513
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.487 0.513
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.487 0.513
M08.9 Juvenile arthritis, unspecified
0.000 0.488 0.512
M08.8 Other juvenile arthritis
0.000 0.488 0.512
M08.4 Pauciarticular juvenile arthritis
0.000 0.488 0.512
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.488 0.512
M08.2 Juvenile arthritis with systemic onset
0.000 0.488 0.512
M08.1 Juvenile ankylosing spondylitis
0.000 0.488 0.512
M08.0 Juvenile rheumatoid arthritis
0.000 0.488 0.512
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.488 0.512
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.488 0.512
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.488 0.512
M09.0 Juvenile arthritis in psoriasis
0.000 0.488 0.512
M10.0 Idiopathic gout
0.000 0.489 0.511
E55.0 Rickets, active
0.000 0.491 0.508
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.492 0.508
J20.9 Acute bronchitis, unspecified
0.000 0.493 0.507
M34.9 Systemic sclerosis, unspecified
0.000 0.496 0.504
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.499 0.500
J10 Influenza due to identified influenza virus
0.000 0.500 0.500
J98.4 Other disorders of lung
0.000 0.500 0.500
J33.1 Polypoid sinus degeneration
0.000 0.500 0.500
E20 Hypoparathyroidism
0.000 0.502 0.497
J98.1 Pulmonary collapse
0.000 0.503 0.497
E11.3 With ophthalmic complications
0.000 0.503 0.497
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.504 0.496
N48.0 Leukoplakia of penis
0.494 0.506 0.000
J20.7 Acute bronchitis due to echovirus
0.000 0.506 0.493
J20.6 Acute bronchitis due to rhinovirus
0.000 0.506 0.493
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.506 0.493
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.506 0.493
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.506 0.493
J20.2 Acute bronchitis due to streptococcus
0.000 0.506 0.493
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.506 0.493
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.506 0.493
M12.2 Villonodular synovitis (pigmented)
0.000 0.511 0.489
J32.9 Chronic sinusitis, unspecified
0.000 0.513 0.487
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.517 0.483
N48.2 Other inflammatory disorders of penis
0.478 0.522 0.000
J37 Chronic laryngitis and laryngotracheitis
0.000 0.528 0.472
N48.9 Disorder of penis, unspecified
0.471 0.529 0.000
L40-L45 Papulosquamous disorders
0.438 0.529 0.033
J64 Unspecified pneumoconiosis
0.000 0.531 0.469
N48.4 Impotence of organic origin
0.468 0.532 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.532 0.468
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.539 0.461
E45 Retarded development following protein-energy malnutrition
0.000 0.539 0.461
E43 Unspecified severe protein-energy malnutrition
0.000 0.539 0.461
E42 Marasmic kwashiorkor
0.000 0.539 0.461
E41 Nutritional marasmus
0.000 0.539 0.461
E40 Kwashiorkor
0.000 0.539 0.461
J20.8 Acute bronchitis due to other specified organisms
0.000 0.539 0.461
E13 Other specified diabetes mellitus
0.001 0.540 0.460
M34.8 Other forms of systemic sclerosis
0.000 0.540 0.460
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.541 0.459
M34.1 CR(E)ST syndrome
0.000 0.541 0.459
E28.3 Primary ovarian failure
0.000 0.542 0.458
E29.1 Testicular hypofunction
0.000 0.542 0.458
J01.9 Acute sinusitis, unspecified
0.000 0.544 0.456
J43.2 Centrilobular emphysema
0.000 0.545 0.455
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.548 0.451
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.548 0.451
M14.4 Arthropathy in amyloidosis
0.000 0.548 0.451
M14.3 Lipoid dermatoarthritis
0.000 0.548 0.451
M14.2 Diabetic arthropathy
0.000 0.548 0.451
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.548 0.451
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.548 0.451
E23.2 Diabetes insipidus
0.000 0.548 0.452
N48.5 Ulcer of penis
0.452 0.548 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.550 0.450
M07 Psoriatic and enteropathic arthropathies
0.007 0.552 0.442
E22 Hyperfunction of pituitary gland
0.000 0.553 0.447
J06.9 Acute upper respiratory infection, unspecified
0.000 0.554 0.446
E28.9 Ovarian dysfunction, unspecified
0.000 0.556 0.444
E28.8 Other ovarian dysfunction
0.000 0.556 0.444
E28.1 Androgen excess
0.000 0.556 0.444
E28.0 Oestrogen excess
0.000 0.556 0.444
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.558 0.442
J02 Acute pharyngitis
0.000 0.559 0.441
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.561 0.439
M10.4 Other secondary gout
0.000 0.561 0.439
M10.3 Gout due to impairment of renal function
0.000 0.561 0.439
M10.2 Drug-induced gout
0.000 0.561 0.439
M10.1 Lead-induced gout
0.000 0.561 0.439
E50.9 Vitamin A deficiency, unspecified
0.000 0.563 0.436
E50.8 Other manifestations of vitamin A deficiency
0.000 0.563 0.436
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.563 0.436
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.563 0.436
E50.5 Vitamin A deficiency with night blindness
0.000 0.563 0.436
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.563 0.436
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.563 0.436
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.563 0.436
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.563 0.436
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.563 0.436
E51.9 Thiamine deficiency, unspecified
0.000 0.563 0.436
E51.8 Other manifestations of thiamine deficiency
0.000 0.563 0.436
E51.2 Wernicke's encephalopathy
0.000 0.563 0.436
E51.1 Beriberi
0.000 0.563 0.436
E63.9 Nutritional deficiency, unspecified
0.000 0.563 0.436
E63.8 Other specified nutritional deficiencies
0.000 0.563 0.436
E63.1 Imbalance of constituents of food intake
0.000 0.563 0.436
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.563 0.436
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.563 0.436
E64.8 Sequelae of other nutritional deficiencies
0.000 0.563 0.436
E64.3 Sequelae of rickets
0.000 0.563 0.436
E64.2 Sequelae of vitamin C deficiency
0.000 0.563 0.436
E64.1 Sequelae of vitamin A deficiency
0.000 0.563 0.436
E64.0 Sequelae of protein-energy malnutrition
0.000 0.563 0.436
G37 Other demyelinating diseases of central nervous system
0.000 0.564 0.436
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.564 0.436
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.567 0.432
M13 Other arthritis
0.000 0.568 0.432
J98.3 Compensatory emphysema
0.000 0.568 0.432
E25 Adrenogenital disorders
0.000 0.568 0.431
E11.1 With ketoacidosis
0.000 0.568 0.432
E53.1 Pyridoxine deficiency
0.000 0.570 0.430
E53.0 Riboflavin deficiency
0.000 0.570 0.430
J96.9 Respiratory failure, unspecified
0.000 0.571 0.428
J96.1 Chronic respiratory failure
0.000 0.571 0.428
J96.0 Acute respiratory failure
0.000 0.571 0.428
E26.0 Primary hyperaldosteronism
0.000 0.572 0.428
J01.0 Acute maxillary sinusitis
0.000 0.573 0.427
# Top node
0.000 0.574 0.426
G36 Other acute disseminated demyelination
0.000 0.574 0.426
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.575 0.425
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.576 0.424
M20 Acquired deformities of fingers and toes
0.000 0.576 0.424
E56.9 Vitamin deficiency, unspecified
0.000 0.576 0.424
E56.8 Deficiency of other vitamins
0.000 0.576 0.424
E56.0 Deficiency of vitamin E
0.000 0.576 0.424
E34.0 Carcinoid syndrome
0.000 0.576 0.423
J11 Influenza, virus not identified
0.000 0.580 0.420

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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