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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2647089
log Bayes Factor = 113.847
Chromosome 6   position 32,681,568  (GRCh37) Explore rs2647089 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
J47 Bronchiectasis
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.998 0.002 0.000
E10.4 With neurological complications
0.000 0.002 0.998
M05 Seropositive rheumatoid arthritis
0.000 0.002 0.998
Chapter X Diseases of the respiratory system
0.000 0.002 0.998
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.003 0.997
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.004 0.996
M05-M14 Inflammatory polyarthropathies
0.000 0.004 0.996
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.004 0.996
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.005 0.995
K90.0 Coeliac disease
0.000 0.007 0.993
J20-J22 Other acute lower respiratory infections
0.000 0.015 0.985
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.019 0.981
E10.5 With peripheral circulatory complications
0.000 0.022 0.978
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.023 0.977
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.024 0.976
E05.9 Thyrotoxicosis, unspecified
0.000 0.026 0.974
E10.2 With renal complications
0.000 0.026 0.974
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.026 0.974
J22 Unspecified acute lower respiratory infection
0.000 0.028 0.972
L40.0 Psoriasis vulgaris
0.969 0.031 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.040 0.960
E16 Other disorders of pancreatic internal secretion
0.000 0.044 0.956
E14 Unspecified diabetes mellitus
0.000 0.044 0.956
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.046 0.954
M06.3 Rheumatoid nodule
0.000 0.050 0.950
M06.0 Seronegative rheumatoid arthritis
0.000 0.052 0.948
J81 Pulmonary oedema
0.000 0.053 0.947
E16.2 Hypoglycaemia, unspecified
0.000 0.055 0.945
J80 Adult respiratory distress syndrome
0.000 0.056 0.944
J84 Other interstitial pulmonary diseases
0.000 0.065 0.935
E14.3 With ophthalmic complications
0.000 0.065 0.935
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.075 0.925
M35.1 Other overlap syndromes
0.000 0.078 0.922
E06 Thyroiditis
0.000 0.078 0.922
E04 Other non-toxic goitre
0.000 0.083 0.917
M06.34 Rheumatoid nodule (Hand)
0.000 0.090 0.910
E10.0 With coma
0.000 0.136 0.864
L40.4 Guttate psoriasis
0.860 0.140 0.000
E06.3 Autoimmune thyroiditis
0.000 0.145 0.855
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.146 0.854
E10.8 With unspecified complications
0.000 0.149 0.851
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.155 0.845
E50-E64 Other nutritional deficiencies
0.000 0.158 0.842
J95-J99 Other diseases of the respiratory system
0.000 0.165 0.834
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.166 0.833
E04.0 Non-toxic diffuse goitre
0.000 0.173 0.827
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.174 0.826
M35.2 Behcet's disease
0.000 0.177 0.823
L40.1 Generalised pustular psoriasis
0.813 0.187 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.188 0.812
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.189 0.811
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.191 0.809
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.196 0.804
E04.2 Non-toxic multinodular goitre
0.000 0.196 0.804
L40.8 Other psoriasis
0.790 0.210 0.000
J42 Unspecified chronic bronchitis
0.000 0.218 0.782
J46 Status asthmaticus
0.000 0.219 0.780
J21 Acute bronchiolitis
0.000 0.221 0.779
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.223 0.777
E07 Other disorders of thyroid
0.000 0.223 0.776
M06.4 Inflammatory polyarthropathy
0.000 0.225 0.775
L40.3 Pustulosis palmaris et plantaris
0.764 0.236 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.236 0.764
E10.6 With other specified complications
0.000 0.236 0.764
J84.8 Other specified interstitial pulmonary diseases
0.000 0.250 0.750
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.250 0.750
J41 Simple and mucopurulent chronic bronchitis
0.000 0.255 0.745
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.261 0.739
E04.9 Non-toxic goitre, unspecified
0.000 0.262 0.738
E05.8 Other thyrotoxicosis
0.000 0.272 0.728
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.274 0.726
M12 Other specific arthropathies
0.000 0.275 0.725
E20-E35 Disorders of other endocrine glands
0.000 0.277 0.723
E61 Deficiency of other nutrient elements
0.000 0.280 0.720
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
M05.8 Other seropositive rheumatoid arthritis
0.000 0.285 0.715
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.285 0.715
M05.2 Rheumatoid vasculitis
0.000 0.285 0.715
M05.1 Rheumatoid lung disease
0.000 0.285 0.715
M05.0 Felty's syndrome
0.000 0.285 0.715
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.286 0.714
M08 Juvenile arthritis
0.000 0.286 0.714
J20 Acute bronchitis
0.000 0.288 0.712
E06.9 Thyroiditis, unspecified
0.000 0.296 0.704
E14.1 With ketoacidosis
0.000 0.297 0.703
E15 Nondiabetic hypoglycaemic coma
0.000 0.302 0.698
M35.8 Other specified systemic involvement of connective tissue
0.000 0.304 0.696
E27 Other disorders of adrenal gland
0.000 0.304 0.696
E14.5 With peripheral circulatory complications
0.000 0.305 0.694
E55 Vitamin D deficiency
0.000 0.312 0.688
J00-J06 Acute upper respiratory infections
0.000 0.314 0.686
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.315 0.685
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.315 0.685
E16.4 Abnormal secretion of gastrin
0.000 0.315 0.685
E16.3 Increased secretion of glucagon
0.000 0.315 0.685
E14.7 With multiple complications
0.000 0.315 0.685
E14.6 With other specified complications
0.000 0.315 0.685
E14.0 With coma
0.000 0.315 0.685
E27.1 Primary adrenocortical insufficiency
0.000 0.316 0.684
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.318 0.682
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.319 0.681
M06.38 Rheumatoid nodule (Other)
0.000 0.319 0.681
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.319 0.681
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.319 0.681
M06.33 Rheumatoid nodule (Forearm)
0.000 0.319 0.681
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.319 0.681
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.319 0.681
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.320 0.680
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.320 0.679
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.320 0.679
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.320 0.679
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.320 0.679
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.320 0.679
J84.0 Alveolar and parietoalveolar conditions
0.000 0.329 0.670
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.330 0.669
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.333 0.667
E14.8 With unspecified complications
0.000 0.335 0.665
E14.2 Withrenal complications
0.000 0.335 0.665
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.338 0.662
E06.5 Other chronic thyroiditis
0.000 0.339 0.661
E06.4 Drug-induced thyroiditis
0.000 0.339 0.661
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.339 0.661
E06.1 Subacute thyroiditis
0.000 0.339 0.661
E06.0 Acute thyroiditis
0.000 0.339 0.661
J33 Nasal polyp
0.000 0.341 0.659
E04.8 Other specified non-toxic goitre
0.000 0.342 0.658
J30-J39 Other diseases of upper respiratory tract
0.000 0.346 0.654
J33.9 Nasal polyp, unspecified
0.000 0.354 0.646
E40-E46 Malnutrition
0.000 0.354 0.645
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.360 0.640
E14.4 With neurological complications
0.000 0.361 0.639
M35.7 Hypermobility syndrome
0.000 0.366 0.634
J21.9 Acute bronchiolitis, unspecified
0.000 0.368 0.632
M14 Arthropathies in other diseases classified elsewhere
0.000 0.368 0.632
E07.8 Other specified disorders of thyroid
0.000 0.379 0.621
E14.9 Without complications
0.000 0.381 0.619
J98 Other respiratory disorders
0.000 0.382 0.618
J99.0 Rheumatoid lung disease
0.000 0.385 0.615
H36 Retinal disorders in diseases classified elsewhere
0.000 0.388 0.612
M10 Gout
0.000 0.391 0.609
N48 Other disorders of penis
0.609 0.391 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.392 0.608
J33.0 Polyp of nasal cavity
0.000 0.395 0.605
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.396 0.604
E63 Other nutritional deficiencies
0.000 0.396 0.604
E51 Thiamine deficiency
0.000 0.396 0.604
E50 Vitamin A deficiency
0.000 0.396 0.604
E60 Dietary zinc deficiency
0.000 0.396 0.604
E59 Dietary selenium deficiency
0.000 0.396 0.604
E54 Ascorbic acid deficiency
0.000 0.396 0.604
E52 Niacin deficiency [pellagra]
0.000 0.396 0.604
E53 Deficiency of other B group vitamins
0.000 0.397 0.603
J96 Respiratory failure, not elsewhere classified
0.000 0.402 0.598
J33.8 Other polyp of sinus
0.000 0.402 0.598
E28 Ovarian dysfunction
0.000 0.403 0.597
E61.1 Iron deficiency
0.000 0.403 0.597
N48.1 Balanoposthitis
0.597 0.403 0.000
N48.8 Other specified disorders of penis
0.591 0.409 0.000
E56 Other vitamin deficiencies
0.000 0.414 0.586
J60-J70 Lung diseases due to external agents
0.000 0.420 0.580
E55.9 Vitamin D deficiency, unspecified
0.000 0.422 0.578
J98.9 Respiratory disorder, unspecified
0.000 0.423 0.577
N48.6 Balanitis xerotica obliterans
0.576 0.424 0.000
E61.2 Magnesium deficiency
0.000 0.425 0.575
J00 Acute nasopharyngitis [common cold]
0.000 0.425 0.575
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.429 0.571
J43 Emphysema
0.000 0.430 0.570
J41.0 Simple chronic bronchitis
0.000 0.437 0.563
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.441 0.559
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.441 0.559
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.441 0.559
E07.1 Dyshormogenetic goitre
0.000 0.443 0.557
E07.0 Hypersecretion of calcitonin
0.000 0.443 0.557
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.444 0.555
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.444 0.555
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.444 0.555
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.444 0.555
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.444 0.555
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.444 0.555
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.444 0.555
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.444 0.555
E29 Testicular dysfunction
0.000 0.445 0.555
M12.3 Palindromic rheumatism
0.000 0.445 0.555
E07.9 Disorder of thyroid, unspecified
0.000 0.449 0.551
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.453 0.547
M11 Other crystal arthropathies
0.000 0.454 0.545
E26 Hyperaldosteronism
0.000 0.456 0.544
J40 Bronchitis, not specified as acute or chronic
0.000 0.458 0.542
E23 Hypofunction and other disorders of pituitary gland
0.000 0.462 0.538
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.465 0.534
J41.1 Mucopurulent chronic bronchitis
0.000 0.465 0.534
E16.1 Other hypoglycaemia
0.000 0.467 0.532
J01 Acute sinusitis
0.000 0.467 0.533
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.469 0.531
N48.0 Leukoplakia of penis
0.530 0.470 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.471 0.529
E58 Dietary calcium deficiency
0.000 0.473 0.527
E34 Other endocrine disorders
0.000 0.479 0.521
J98.1 Pulmonary collapse
0.000 0.480 0.520
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.480 0.520
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.480 0.520
M12.5 Traumatic arthropathy
0.000 0.480 0.520
M12.4 Intermittent hydrarthrosis
0.000 0.480 0.520
M12.1 Kaschin-Beck disease
0.000 0.480 0.520
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.480 0.520
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.481 0.518
E32 Diseases of thymus
0.000 0.481 0.518
E31 Polyglandular dysfunction
0.000 0.481 0.518
E30 Disorders of puberty, not elsewhere classified
0.000 0.481 0.518
J20.9 Acute bronchitis, unspecified
0.000 0.483 0.517
E61.9 Deficiency of nutrient element, unspecified
0.000 0.484 0.516
E61.8 Deficiency of other specified nutrient elements
0.000 0.484 0.516
E61.7 Deficiency of multiple nutrient elements
0.000 0.484 0.516
E61.6 Vanadium deficiency
0.000 0.484 0.516
E61.5 Molybdenum deficiency
0.000 0.484 0.516
E61.4 Chromium deficiency
0.000 0.484 0.516
E61.3 Manganese deficiency
0.000 0.484 0.516
E61.0 Copper deficiency
0.000 0.484 0.516
N48.2 Other inflammatory disorders of penis
0.515 0.485 0.000
J98.4 Other disorders of lung
0.000 0.485 0.515
J09-J18 Influenza and pneumonia
0.000 0.486 0.514
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.486 0.514
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.486 0.514
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.486 0.514
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.486 0.514
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.486 0.514
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.486 0.514
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.486 0.514
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.486 0.514
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.486 0.514
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M05.09 Felty's syndrome (Site unspecified)
0.000 0.487 0.513
M05.08 Felty's syndrome (Other)
0.000 0.487 0.513
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.487 0.513
M05.06 Felty's syndrome (Lower leg)
0.000 0.487 0.513
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.487 0.513
M05.04 Felty's syndrome (Hand)
0.000 0.487 0.513
M05.03 Felty's syndrome (Forearm)
0.000 0.487 0.513
M05.02 Felty's syndrome (Upper arm)
0.000 0.487 0.513
M05.01 Felty's syndrome (Shoulder region)
0.000 0.487 0.513
M05.00 Felty's syndrome (Multiple sites)
0.000 0.487 0.513
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.487 0.513
M05.18 Rheumatoid lung disease (Other)
0.000 0.487 0.513
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.487 0.513
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.487 0.513
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.487 0.513
M05.14 Rheumatoid lung disease (Hand)
0.000 0.487 0.513
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.487 0.513
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.487 0.513
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.487 0.513
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.487 0.513
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.487 0.513
M05.28 Rheumatoid vasculitis (Other)
0.000 0.487 0.513
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.487 0.513
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.487 0.513
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.487 0.513
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.487 0.513
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.487 0.513
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.487 0.513
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.487 0.513
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.487 0.513
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.487 0.513
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.487 0.513
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.487 0.513
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.487 0.513
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.487 0.513
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.487 0.513
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.487 0.513
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.487 0.513
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.487 0.513
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.487 0.513
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.487 0.513
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.487 0.513
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.487 0.513
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.487 0.513
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.487 0.513
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.487 0.513
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.487 0.513
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.487 0.513
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.487 0.513
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.487 0.513
E11 Non-insulin-dependent diabetes mellitus
0.000 0.487 0.513
M08.9 Juvenile arthritis, unspecified
0.000 0.488 0.512
M08.8 Other juvenile arthritis
0.000 0.488 0.512
M08.4 Pauciarticular juvenile arthritis
0.000 0.488 0.512
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.488 0.512
M08.2 Juvenile arthritis with systemic onset
0.000 0.488 0.512
M08.1 Juvenile ankylosing spondylitis
0.000 0.488 0.512
M08.0 Juvenile rheumatoid arthritis
0.000 0.488 0.512
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.488 0.512
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.488 0.512
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.488 0.512
M09.0 Juvenile arthritis in psoriasis
0.000 0.488 0.512
M20-M25 Other joint disorders
0.000 0.488 0.512
J32 Chronic sinusitis
0.000 0.489 0.511
J20.7 Acute bronchitis due to echovirus
0.000 0.489 0.510
J20.6 Acute bronchitis due to rhinovirus
0.000 0.489 0.510
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.489 0.510
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.489 0.510
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.489 0.510
J20.2 Acute bronchitis due to streptococcus
0.000 0.489 0.510
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.489 0.510
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.489 0.510
M10.0 Idiopathic gout
0.000 0.490 0.510
J20.8 Acute bronchitis due to other specified organisms
0.000 0.491 0.509
N48.4 Impotence of organic origin
0.507 0.493 0.000
M34 Systemic sclerosis
0.000 0.494 0.506
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.497 0.503
E28.2 Polycystic ovarian syndrome
0.000 0.497 0.503
N48.9 Disorder of penis, unspecified
0.501 0.499 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.501 0.499
E27.0 Other adrenocortical overactivity
0.000 0.501 0.499
E11.3 With ophthalmic complications
0.000 0.506 0.494
E55.0 Rickets, active
0.000 0.506 0.493
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.507 0.493
J04 Acute laryngitis and tracheitis
0.000 0.509 0.491
J33.1 Polypoid sinus degeneration
0.000 0.510 0.490
M12.2 Villonodular synovitis (pigmented)
0.000 0.510 0.489
M34.9 Systemic sclerosis, unspecified
0.000 0.518 0.482
E20 Hypoparathyroidism
0.000 0.518 0.482
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.518 0.482
N48.5 Ulcer of penis
0.480 0.520 0.000
J10 Influenza due to identified influenza virus
0.000 0.525 0.474
J32.9 Chronic sinusitis, unspecified
0.000 0.529 0.471
E53.9 Vitamin B deficiency, unspecified
0.000 0.530 0.470
J64 Unspecified pneumoconiosis
0.000 0.534 0.466
J37 Chronic laryngitis and laryngotracheitis
0.000 0.535 0.465
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.537 0.463
E45 Retarded development following protein-energy malnutrition
0.000 0.537 0.463
E43 Unspecified severe protein-energy malnutrition
0.000 0.537 0.463
E42 Marasmic kwashiorkor
0.000 0.537 0.463
E41 Nutritional marasmus
0.000 0.537 0.463
E40 Kwashiorkor
0.000 0.537 0.463
L40-L45 Papulosquamous disorders
0.436 0.538 0.025
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.542 0.458
E13 Other specified diabetes mellitus
0.001 0.544 0.455
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.547 0.453
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.547 0.453
M14.4 Arthropathy in amyloidosis
0.000 0.547 0.453
M14.3 Lipoid dermatoarthritis
0.000 0.547 0.453
M14.2 Diabetic arthropathy
0.000 0.547 0.453
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.547 0.453
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.547 0.453
J43.2 Centrilobular emphysema
0.000 0.549 0.451
M07 Psoriatic and enteropathic arthropathies
0.007 0.551 0.442
E65-E68 Obesity and other hyperalimentation
0.000 0.556 0.444
J98.3 Compensatory emphysema
0.000 0.557 0.443
M34.8 Other forms of systemic sclerosis
0.000 0.560 0.440
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.561 0.439
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.562 0.438
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.562 0.438
M10.4 Other secondary gout
0.000 0.563 0.437
M10.3 Gout due to impairment of renal function
0.000 0.563 0.437
M10.2 Drug-induced gout
0.000 0.563 0.437
M10.1 Lead-induced gout
0.000 0.563 0.437
E28.3 Primary ovarian failure
0.000 0.565 0.435
E29.1 Testicular hypofunction
0.000 0.565 0.435
M34.1 CR(E)ST syndrome
0.000 0.565 0.435
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.567 0.433
E50.9 Vitamin A deficiency, unspecified
0.000 0.567 0.433
E50.8 Other manifestations of vitamin A deficiency
0.000 0.567 0.433
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.567 0.433
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.567 0.433
E50.5 Vitamin A deficiency with night blindness
0.000 0.567 0.433
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.567 0.433
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.567 0.433
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.567 0.433
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.567 0.433
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.567 0.433
E51.9 Thiamine deficiency, unspecified
0.000 0.567 0.433
E51.8 Other manifestations of thiamine deficiency
0.000 0.567 0.433
E51.2 Wernicke's encephalopathy
0.000 0.567 0.433
E51.1 Beriberi
0.000 0.567 0.433
E63.9 Nutritional deficiency, unspecified
0.000 0.567 0.433
E63.8 Other specified nutritional deficiencies
0.000 0.567 0.433
E63.1 Imbalance of constituents of food intake
0.000 0.567 0.433
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.567 0.433
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.567 0.433
E64.8 Sequelae of other nutritional deficiencies
0.000 0.567 0.433
E64.3 Sequelae of rickets
0.000 0.567 0.433
E64.2 Sequelae of vitamin C deficiency
0.000 0.567 0.433
E64.1 Sequelae of vitamin A deficiency
0.000 0.567 0.433
E64.0 Sequelae of protein-energy malnutrition
0.000 0.567 0.433
E53.1 Pyridoxine deficiency
0.000 0.568 0.432
E53.0 Riboflavin deficiency
0.000 0.568 0.432
E11.1 With ketoacidosis
0.000 0.570 0.430
J96.9 Respiratory failure, unspecified
0.000 0.571 0.429
J96.1 Chronic respiratory failure
0.000 0.571 0.429
J96.0 Acute respiratory failure
0.000 0.571 0.429
E28.9 Ovarian dysfunction, unspecified
0.000 0.572 0.428
E28.8 Other ovarian dysfunction
0.000 0.572 0.428
E28.1 Androgen excess
0.000 0.572 0.428
E28.0 Oestrogen excess
0.000 0.572 0.428
E22 Hyperfunction of pituitary gland
0.000 0.572 0.428
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.576 0.424
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.576 0.424
G37 Other demyelinating diseases of central nervous system
0.000 0.577 0.423
M13 Other arthritis
0.000 0.579 0.421
E56.9 Vitamin deficiency, unspecified
0.000 0.579 0.420
E56.8 Deficiency of other vitamins
0.000 0.579 0.420
E56.0 Deficiency of vitamin E
0.000 0.579 0.420
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.580 0.420
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.580 0.420
J06.9 Acute upper respiratory infection, unspecified
0.000 0.580 0.420
E25 Adrenogenital disorders
0.000 0.582 0.417
N48.3 Priapism
0.418 0.582 0.000
E23.2 Diabetes insipidus
0.000 0.583 0.417
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.584 0.416
J66 Airway disease due to specific organic dust
0.000 0.584 0.416
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.584 0.416
J62 Pneumoconiosis due to dust containing silica
0.000 0.584 0.416
J65 Pneumoconiosis associated with tuberculosis
0.000 0.584 0.416
E26.0 Primary hyperaldosteronism
0.000 0.584 0.416
J01.9 Acute sinusitis, unspecified
0.000 0.589 0.411

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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