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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs268786
log Bayes Factor = 2.87359
Chromosome 1   position 237,355,985  (GRCh37) Explore rs268786 on Ensembl!
Variant rs268786 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.990 0.010 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.987 0.013 0.000
Chapter IX Diseases of the circulatory system
0.978 0.022 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.946 0.054 0.000
I30-I52 Other forms of heart disease
0.936 0.064 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.924 0.076 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.918 0.082 0.000
M15-M19 Arthrosis
0.917 0.083 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.913 0.087 0.000
Chapter XX External causes of morbidity and mortality
0.910 0.090 0.000
Chapter XIV Diseases of the genitourinary system
0.903 0.097 0.000
M50-M54 Other dorsopathies
0.898 0.102 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.888 0.112 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.885 0.115 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.880 0.120 0.000
I26 Pulmonary embolism
0.862 0.138 0.000
Z51 Other medical care
0.855 0.145 0.000
Chapter XI Diseases of the digestive system
0.851 0.149 0.000
Z45 Adjustment and management of implanted device
0.849 0.151 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.846 0.154 0.000
Z30 Contraceptive management
0.846 0.154 0.000
Chapter X Diseases of the respiratory system
0.842 0.158 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.836 0.164 0.000
M54 Dorsalgia
0.834 0.166 0.000
I50 Heart failure
0.826 0.174 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.825 0.175 0.000
I35 Nonrheumatic aortic valve disorders
0.825 0.175 0.000
M45-M49 Spondylopathies
0.823 0.177 0.000
M86-M90 Other osteopathies
0.820 0.180 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.819 0.181 0.000
M20-M25 Other joint disorders
0.813 0.187 0.000
Z30.2 Sterilisation
0.812 0.188 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.812 0.188 0.000
Chapter I Certain infectious and parasitic diseases
0.799 0.201 0.000
S60-S69 Injuries to the wrist and hand
0.799 0.201 0.000
Z42 Follow-up care involving plastic surgery
0.797 0.203 0.000
M19 Other arthrosis
0.795 0.205 0.000
M05-M14 Inflammatory polyarthropathies
0.792 0.208 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.780 0.220 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.778 0.222 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.776 0.224 0.000
I42 Cardiomyopathy
0.768 0.232 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.765 0.235 0.000
E00-E07 Disorders of thyroid gland
0.765 0.235 0.000
N95 Menopausal and other perimenopausal disorders
0.765 0.235 0.000
N80 Endometriosis
0.764 0.236 0.000
Z45.2 Adjustment and management of vascular access device
0.761 0.239 0.000
M16 Coxarthrosis [arthrosis of hip]
0.760 0.240 0.000
Chapter XXII Codes for special purposes
0.757 0.243 0.000
S80-S89 Injuries to the knee and lower leg
0.756 0.244 0.000
I05-I09 Chronic rheumatic heart diseases
0.755 0.245 0.000
J20-J22 Other acute lower respiratory infections
0.753 0.247 0.000
Z51.1 Chemotherapy session for neoplasm
0.753 0.247 0.000
N17-N19 Renal failure
0.752 0.248 0.000
M17 Gonarthrosis [arthrosis of knee]
0.750 0.250 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.750 0.250 0.000
I77 Other disorders of arteries and arterioles
0.746 0.254 0.000
M65-M68 Disorders of synovium and tendon
0.746 0.254 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.742 0.258 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.740 0.260 0.000
Z50 Care involving use of rehabilitation procedures
0.738 0.262 0.000
W20-W49 Exposure to inanimate mechanical forces
0.736 0.264 0.000
B95-B98 Bacterial, viral and other infectious agents
0.735 0.265 0.000
I10-I15 Hypertensive diseases
0.735 0.265 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.733 0.267 0.000
E20-E35 Disorders of other endocrine glands
0.732 0.268 0.000
I51 Complications and ill-defined descriptions of heart disease
0.731 0.269 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.731 0.269 0.000
I31 Other diseases of pericardium
0.730 0.270 0.000
Z33 Pregnant state, incidental
0.729 0.271 0.000
I50.1 Left ventricular failure
0.729 0.271 0.000
N00-N08 Glomerular diseases
0.726 0.274 0.000
Z36 Antenatal screening
0.725 0.275 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.725 0.275 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.725 0.275 0.000
M00-M03 Infectious arthropathies
0.724 0.275 0.000
M54.5 Low back pain
0.724 0.276 0.000
K70-K77 Diseases of liver
0.720 0.280 0.000
S20-S29 Injuries to the thorax
0.720 0.280 0.000
N87 Dysplasia of cervix uteri
0.720 0.280 0.000
Z49 Care involving dialysis
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T81 Complications of procedures, not elsewhere classified
0.714 0.286 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.712 0.288 0.000
M91-M94 Chondropathies
0.711 0.289 0.000
M25 Other joint disorders, not elsewhere classified
0.711 0.289 0.000
N25-N29 Other disorders of kidney and ureter
0.711 0.289 0.000
S50-S59 Injuries to the elbow and forearm
0.710 0.290 0.000
W00-W19 Falls
0.709 0.291 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.708 0.292 0.000
M60-M63 Disorders of muscles
0.707 0.293 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.705 0.295 0.000
I45 Other conduction disorders
0.704 0.296 0.000
I33 Acute and subacute endocarditis
0.704 0.296 0.000
N10-N16 Renal tubulo-interstitial diseases
0.704 0.296 0.000
I00-I02 Acute rheumatic fever
0.703 0.296 0.000
M47 Spondylosis
0.702 0.298 0.000
E65-E68 Obesity and other hyperalimentation
0.702 0.298 0.000
Z88.6 Personal history of allergy to analgesic agent
0.702 0.298 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.700 0.300 0.000
J95-J99 Other diseases of the respiratory system
0.700 0.300 0.000
K21 Gastro-oesophageal reflux disease
0.699 0.301 0.000
K29 Gastritis and duodenitis
0.699 0.301 0.000
M54.2 Cervicalgia
0.698 0.302 0.000
I35.0 Aortic (valve) stenosis
0.698 0.302 0.000
I73 Other peripheral vascular diseases
0.695 0.305 0.000
M19.9 Arthrosis, unspecified
0.694 0.306 0.000
Z39 Postpartum care and examination
0.693 0.307 0.000
S90-S99 Injuries to the ankle and foot
0.691 0.308 0.000
Z31 Procreative management
0.691 0.309 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.690 0.310 0.000
S61 Open wound of wrist and hand
0.689 0.311 0.000
I34 Nonrheumatic mitral valve disorders
0.689 0.311 0.000
M23 Internal derangement of knee
0.688 0.312 0.000
I36 Nonrheumatic tricuspid valve disorders
0.686 0.314 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.685 0.315 0.000
N99-N99 Other disorders of the genitourinary system
0.685 0.315 0.000
Z41 Procedures for purposes other than remedying health state
0.684 0.315 0.000
I37 Pulmonary valve disorders
0.684 0.316 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.684 0.316 0.000
X60-X84 Intentional self-harm
0.684 0.316 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.684 0.316 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.683 0.317 0.000
I71 Aortic aneurysm and dissection
0.683 0.317 0.000
J22 Unspecified acute lower respiratory infection
0.682 0.318 0.000
I30 Acute pericarditis
0.682 0.318 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.682 0.318 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.681 0.319 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.681 0.319 0.000
Z35 Supervision of high-risk pregnancy
0.680 0.320 0.000
T00-T07 Injuries involving multiple body regions
0.679 0.321 0.000
Z45.8 Adjustment and management of other implanted devices
0.679 0.321 0.000
N95.0 Postmenopausal bleeding
0.678 0.322 0.000
M16.1 Other primary coxarthrosis
0.678 0.322 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.678 0.322 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.677 0.323 0.000
Q80-Q89 Other congenital malformations
0.677 0.323 0.000
M18 Arthrosis of first carpometacarpal joint
0.676 0.323 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.676 0.323 0.000
Z32 Pregnancy examination and test
0.676 0.324 0.000
I74 Arterial embolism and thrombosis
0.676 0.324 0.000
Z44 Fitting and adjustment of external prosthetic device
0.676 0.324 0.000
I40 Acute myocarditis
0.676 0.324 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.675 0.325 0.000
R07 Pain in throat and chest
0.675 0.325 0.000
M50 Cervical disk disorders
0.675 0.325 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.674 0.326 0.000
Y00-Y09 Assault
0.674 0.326 0.000
X50-X57 Overexertion, travel and privation
0.672 0.328 0.000
I52 Other heart disorders in diseases classified elsewhere
0.671 0.329 0.000
I48 Atrial fibrillation and flutter
0.671 0.329 0.000
I41 Myocarditis in diseases classified elsewhere
0.671 0.329 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.671 0.329 0.000
I32 Pericarditis in diseases classified elsewhere
0.671 0.329 0.000
I27 Other pulmonary heart diseases
0.671 0.329 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.671 0.329 0.000
Z52 Donors of organs and tissues
0.671 0.329 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.669 0.331 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.669 0.331 0.000
Z47 Other orthopaedic follow-up care
0.668 0.332 0.000
Z38 Liveborn infants according to place of birth
0.667 0.333 0.000
E50-E64 Other nutritional deficiencies
0.667 0.333 0.000
M80-M85 Disorders of bone density and structure
0.665 0.335 0.000
W75-W84 Other accidental threats to breathing
0.664 0.336 0.000
Z54 Convalescence
0.664 0.336 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.663 0.337 0.000
Z72 Problems related to lifestyle
0.663 0.337 0.000
Q50-Q56 Congenital malformations of genital organs
0.663 0.337 0.000
I28 Other diseases of pulmonary vessels
0.661 0.339 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.661 0.339 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.660 0.340 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.659 0.341 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.659 0.341 0.000
X00-X09 Exposure to smoke, fire and flames
0.659 0.341 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.659 0.341 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.659 0.341 0.000
S10-S19 Injuries to the neck
0.659 0.341 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.658 0.341 0.000
T33-T35 Frostbite
0.658 0.342 0.000
V90-V94 Water transport accidents
0.658 0.342 0.000
V98-V99 Other and unspecified transport accidents
0.658 0.342 0.000
R11 Nausea and vomiting
0.657 0.343 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.657 0.343 0.000
W50-W64 Exposure to animate mechanical forces
0.657 0.343 0.000
V95-V97 Air and space transport accidents
0.657 0.343 0.000
V70-V79 Bus occupant injured in transport accident
0.657 0.343 0.000
M24 Other specific joint derangements
0.657 0.343 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.656 0.344 0.000
Z43 Attention to artificial openings
0.656 0.344 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.656 0.344 0.000
D60-D64 Aplastic and other anaemias
0.656 0.344 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.655 0.344 0.000
X30-X39 Exposure to forces of nature
0.655 0.344 0.000
V10-V19 Pedal cyclist injured in transport accident
0.655 0.344 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.655 0.345 0.000
V01-V09 Pedestrian injured in transport accident
0.654 0.345 0.000
K13 Other diseases of lip and oral mucosa
0.654 0.346 0.000
Z13 Special screening examination for other diseases and disorders
0.653 0.347 0.000
X20-X29 Contact with venomous animals and plants
0.653 0.347 0.000
Z51.2 Other chemotherapy
0.653 0.347 0.000
Y35-Y36 Legal intervention and operations of war
0.653 0.347 0.000
X85-X99 Assault
0.653 0.347 0.000
W65-W74 Accidental drowning and submersion
0.653 0.347 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.653 0.347 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.652 0.348 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.651 0.349 0.000
Q60-Q64 Congenital malformations of the urinary system
0.651 0.349 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.651 0.349 0.000
I72 Other aneurysm
0.650 0.349 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.650 0.350 0.000
J90-J94 Other diseases of pleura
0.650 0.350 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.650 0.350 0.000
V40-V49 Car occupant injured in transport accident
0.650 0.350 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.649 0.351 0.000
E70-E90 Metabolic disorders
0.648 0.352 0.000
M06 Other rheumatoid arthritis
0.648 0.352 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.648 0.352 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.648 0.352 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.647 0.352 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.647 0.353 0.000
E03 Other hypothyroidism
0.646 0.354 0.000
Y10-Y34 Event of undetermined intent
0.645 0.355 0.000
M54.9 Dorsalgia, unspecified
0.645 0.355 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.644 0.356 0.000
Z45.1 Adjustment and management of infusion pump
0.644 0.356 0.000
K12 Stomatitis and related lesions
0.643 0.357 0.000
I70 Atherosclerosis
0.642 0.358 0.000
M53 Other dorsopathies, not elsewhere classified
0.642 0.358 0.000
T79-T79 Certain early complications of trauma
0.641 0.359 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.641 0.359 0.000
Z51.3 Blood transfusion without reported diagnosis
0.640 0.360 0.000
Z51.8 Other specified medical care
0.640 0.360 0.000
X10-X19 Contact with heat and hot substances
0.640 0.360 0.000
I38 Endocarditis, valve unspecified
0.640 0.360 0.000
N93 Other abnormal uterine and vaginal bleeding
0.639 0.361 0.000
K29.7 Gastritis, unspecified
0.638 0.362 0.000
V80-V89 Other land transport accidents
0.638 0.362 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.638 0.362 0.000
I49 Other cardiac arrhythmias
0.638 0.362 0.000
E40-E46 Malnutrition
0.637 0.362 0.000
M89 Other disorders of bone
0.637 0.362 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.634 0.366 0.000
M13 Other arthritis
0.634 0.366 0.000
Q35-Q37 Cleft lip and cleft palate
0.633 0.367 0.000
Z51.5 Palliative care
0.633 0.367 0.000
Q00-Q07 Congenital malformations of the nervous system
0.632 0.368 0.000
M17.1 Other primary gonarthrosis
0.631 0.369 0.000
Z40 Prophylactic surgery
0.630 0.369 0.000
N84 Polyp of female genital tract
0.630 0.369 0.000
M40-M43 Deforming dorsopathies
0.630 0.370 0.000
M45 Ankylosing spondylitis
0.629 0.370 0.000
I50.0 Congestive heart failure
0.629 0.371 0.000
Z34 Supervision of normal pregnancy
0.629 0.371 0.000
K76 Other diseases of liver
0.628 0.372 0.000
M86 Osteomyelitis
0.628 0.372 0.000
N18 Chronic renal failure
0.628 0.372 0.000
M54.3 Sciatica
0.626 0.374 0.000
Chapter VI Diseases of the nervous system
0.625 0.374 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.625 0.375 0.000
N82 Fistulae involving female genital tract
0.625 0.375 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.625 0.375 0.000
D80-D89 Certain disorders involving the immune mechanism
0.624 0.376 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.623 0.377 0.000
M15 Polyarthrosis
0.622 0.377 0.000
N80.9 Endometriosis, unspecified
0.622 0.378 0.000
N80.0 Endometriosis of uterus
0.621 0.379 0.000
M31 Other necrotising vasculopathies
0.621 0.379 0.000
T66-T78 Other and unspecified effects of external causes
0.620 0.379 0.000
V20-V29 Motorcycle rider injured in transport accident
0.619 0.381 0.000
Z51.6 Desensitisation to allergens
0.619 0.381 0.000
N95.2 Postmenopausal atrophic vaginitis
0.619 0.381 0.000
S82 Fracture of lower leg, including ankle
0.618 0.382 0.000
N80.1 Endometriosis of ovary
0.618 0.382 0.000
I35.9 Aortic valve disorder, unspecified
0.617 0.383 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.616 0.383 0.000
I78 Diseases of capillaries
0.616 0.384 0.000
M87 Osteonecrosis
0.615 0.384 0.000
B35-B49 Mycoses
0.615 0.385 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.615 0.385 0.000
Z45.3 Adjustment and management of implanted hearing device
0.614 0.386 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.614 0.386 0.000
I35.1 Aortic (valve) insufficiency
0.614 0.386 0.000
I35.8 Other aortic valve disorders
0.612 0.388 0.000
E04 Other non-toxic goitre
0.612 0.388 0.000
I46 Cardiac arrest
0.611 0.389 0.000
R87 Abnormal findings in specimens from female genital organs
0.611 0.389 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.611 0.389 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.611 0.389 0.000
S68 Traumatic amputation of wrist and hand
0.610 0.389 0.000
J98 Other respiratory disorders
0.610 0.390 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.610 0.390 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.610 0.390 0.000
M54.8 Other dorsalgia
0.609 0.391 0.000
M51 Other intervertebral disk disorders
0.609 0.391 0.000
Z30.9 Contraceptive management, unspecified
0.609 0.391 0.000
T86 Failure and rejection of transplanted organs and tissues
0.609 0.391 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.609 0.391 0.000
S62 Fracture at wrist and hand level
0.609 0.391 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.608 0.392 0.000
Z30.4 Surveillance of contraceptive drugs
0.608 0.392 0.000
S64 Injury of nerves at wrist and hand level
0.608 0.392 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.608 0.392 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.605 0.395 0.000
J09-J18 Influenza and pneumonia
0.605 0.395 0.000
N96 Habitual aborter
0.604 0.396 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.604 0.396 0.000
N98 Complications associated with artificial fertilisation
0.604 0.396 0.000
K26 Duodenal ulcer
0.603 0.397 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.603 0.397 0.000
S70-S79 Injuries to the hip and thigh
0.601 0.399 0.000
M90 Osteopathies in diseases classified elsewhere
0.600 0.400 0.000
I50.9 Heart failure, unspecified
0.600 0.400 0.000
M54.56 Low back pain (Lumbar region)
0.599 0.401 0.000
M54.6 Pain in thoracic spine
0.599 0.401 0.000
I77.1 Stricture of artery
0.598 0.402 0.000
S69 Other and unspecified injuries of wrist and hand
0.598 0.402 0.000
Z72.0 Tobacco use
0.598 0.402 0.000
M54.0 Panniculitis affecting regions of neck and back
0.598 0.402 0.000
M88 Paget's disease of bone [osteitis deformans]
0.597 0.403 0.000
K22 Other diseases of oesophagus
0.597 0.403 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.597 0.403 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.597 0.403 0.000
N60-N64 Disorders of breast
0.597 0.403 0.000
N91 Absent, scanty and rare menstruation
0.596 0.404 0.000
M47.8 Other spondylosis
0.596 0.404 0.000
M34 Systemic sclerosis
0.595 0.404 0.000
R14 Flatulence and related conditions
0.594 0.406 0.000
J00-J06 Acute upper respiratory infections
0.593 0.407 0.000
Z30.0 General counselling and advice on contraception
0.592 0.407 0.000
M54.4 Lumbago with sciatica
0.592 0.408 0.000
I44 Atrioventricular and left bundle-branch block
0.592 0.408 0.000
R07.2 Precordial pain
0.591 0.408 0.000
Z30.8 Other contraceptive management
0.591 0.409 0.000
M54.22 Cervicalgia (Cervical region)
0.590 0.410 0.000
T87 Complications peculiar to reattachment and amputation
0.589 0.410 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.589 0.411 0.000
I42.0 Dilated cardiomyopathy
0.589 0.411 0.000
D68 Other coagulation defects
0.589 0.411 0.000
R00 Abnormalities of heart beat
0.588 0.411 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.588 0.412 0.000
K04 Diseases of pulp and periapical tissues
0.588 0.412 0.000
M19.0 Primary arthrosis of other joints
0.588 0.412 0.000
M19.1 Posttraumatic arthrosis of other joints
0.588 0.412 0.000
N87.0 Mild cervical dysplasia
0.587 0.413 0.000
K08 Other disorders of teeth and supporting structures
0.587 0.413 0.000
R07.4 Chest pain, unspecified
0.587 0.413 0.000
R12 Heartburn
0.587 0.413 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.586 0.414 0.000
Z89 Acquired absence of limb
0.586 0.414 0.000
Z88.2 Personal history of allergy to sulphonamides
0.586 0.414 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.585 0.415 0.000
B65-B83 Helminthiases
0.585 0.415 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.585 0.415 0.000
R04 Haemorrhage from respiratory passages
0.585 0.415 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.585 0.415 0.000
A80-A89 Viral infections of the central nervous system
0.585 0.415 0.000
I73.9 Peripheral vascular disease, unspecified
0.584 0.416 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.584 0.416 0.000
M25.7 Osteophyte
0.584 0.416 0.000
A15-A19 Tuberculosis
0.584 0.416 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.584 0.416 0.000
M54.1 Radiculopathy
0.583 0.417 0.000
K07 Dentofacial anomalies [including malocclusion]
0.583 0.417 0.000
Z51.0 Radiotherapy session
0.583 0.417 0.000
Z76 Persons encountering health services in other circumstances
0.583 0.417 0.000
M17.0 Primary gonarthrosis, bilateral
0.582 0.418 0.000
M54.57 Low back pain (Lumbosacral region)
0.582 0.418 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.582 0.418 0.000
S40-S49 Injuries to the shoulder and upper arm
0.581 0.419 0.000
Z51.9 Medical care, unspecified
0.581 0.419 0.000
I08 Multiple valve diseases
0.580 0.420 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.580 0.420 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.580 0.420 0.000
Z95.1 Presence of aortocoronary bypass graft
0.580 0.420 0.000
M46 Other inflammatory spondylopathies
0.579 0.420 0.000
Z12 Special screening examination for neoplasms
0.578 0.421 0.000
Z30.3 Menstrual extraction
0.578 0.422 0.000
M48 Other spondylopathies
0.578 0.422 0.000
J60-J70 Lung diseases due to external agents
0.578 0.422 0.000
M33 Dermatopolymyositis
0.577 0.423 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.577 0.423 0.000
B15-B19 Viral hepatitis
0.577 0.423 0.000
S61.0 Open wound of finger(s) without damage to nail
0.577 0.423 0.000
K14 Diseases of tongue
0.576 0.424 0.000
I42.2 Other hypertrophic cardiomyopathy
0.576 0.424 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.576 0.424 0.000
Z53.8 Procedure not carried out for other reasons
0.576 0.424 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.575 0.424 0.000
K01 Embedded and impacted teeth
0.575 0.424 0.000
O80-O84 Delivery
0.575 0.424 0.000
K09 Cysts of oral region, not elsewhere classified
0.575 0.424 0.000
M12 Other specific arthropathies
0.575 0.425 0.000
M19.8 Other specified arthrosis
0.575 0.425 0.000
A20-A28 Certain zoonotic bacterial diseases
0.575 0.425 0.000
Z50.1 Other physical therapy
0.574 0.426 0.000
M49 Spondylopathies in diseases classified elsewhere
0.574 0.426 0.000
I10 Essential (primary) hypertension
0.574 0.426 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.573 0.427 0.000
A75-A79 Rickettsioses
0.573 0.427 0.000
A70-A74 Other diseases caused by chlamydiae
0.573 0.427 0.000
M32 Systemic lupus erythematosus
0.573 0.427 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.571 0.428 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.572 0.428 0.000
I47 Paroxysmal tachycardia
0.571 0.429 0.000
N97 Female infertility
0.571 0.429 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.571 0.429 0.000
N80.2 Endometriosis of Fallopian tube
0.571 0.429 0.000
M08 Juvenile arthritis
0.570 0.429 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.571 0.429 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.570 0.429 0.000
N80.8 Other endometriosis
0.570 0.430 0.000
I77.6 Arteritis, unspecified
0.570 0.430 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.570 0.430 0.000
K27 Peptic ulcer, site unspecified
0.569 0.431 0.000
E03.9 Hypothyroidism, unspecified
0.569 0.431 0.000
S80 Superficial injury of lower leg
0.569 0.431 0.000
E27 Other disorders of adrenal gland
0.568 0.432 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.568 0.432 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.567 0.433 0.000
M16.7 Other secondary coxarthrosis
0.567 0.433 0.000
A65-A69 Other spirochaetal diseases
0.567 0.433 0.000
B99-B99 Other infectious diseases
0.566 0.433 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.566 0.433 0.000
I05 Rheumatic mitral valve diseases
0.566 0.434 0.000
K20 Oesophagitis
0.566 0.434 0.000
I42.8 Other cardiomyopathies
0.564 0.436 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.564 0.436 0.000
N17 Acute renal failure
0.564 0.436 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.564 0.436 0.000
M21 Other acquired deformities of limbs
0.563 0.436 0.000
M16.3 Other dysplastic coxarthrosis
0.563 0.437 0.000
M67 Other disorders of synovium and tendon
0.563 0.437 0.000
M14 Arthropathies in other diseases classified elsewhere
0.563 0.437 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.563 0.437 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.562 0.437 0.000
Y86 Sequelae of other accidents
0.562 0.437 0.000
S67 Crushing injury of wrist and hand
0.562 0.438 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.562 0.438 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.562 0.438 0.000
M19.2 Other secondary arthrosis
0.562 0.438 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.562 0.438 0.000
Z94 Transplanted organ and tissue status
0.561 0.439 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.561 0.439 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.561 0.439 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.561 0.439 0.000
I51.9 Heart disease, unspecified
0.561 0.439 0.000
M11 Other crystal arthropathies
0.560 0.439 0.000
Z37 Outcome of delivery
0.560 0.439 0.000
I42.6 Alcoholic cardiomyopathy
0.560 0.440 0.000
M30 Polyarteritis nodosa and related conditions
0.560 0.440 0.000
D55-D59 Haemolytic anaemias
0.560 0.440 0.000
E66 Obesity
0.560 0.440 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.559 0.440 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.559 0.441 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.559 0.441 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.559 0.441 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.559 0.441 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.559 0.441 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.558 0.442 0.000
K11 Diseases of salivary glands
0.558 0.442 0.000
I42.9 Cardiomyopathy, unspecified
0.558 0.442 0.000
S27 Injury of other and unspecified intrathoracic organs
0.558 0.442 0.000
Z74 Problems related to care-provider dependency
0.557 0.443 0.000
K35-K38 Diseases of appendix
0.557 0.443 0.000
W25 Contact with sharp glass
0.557 0.443 0.000
I31.3 Pericardial effusion (noninflammatory)
0.557 0.443 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.557 0.443 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.557 0.443 0.000
N80.5 Endometriosis of intestine
0.557 0.443 0.000
J20 Acute bronchitis
0.556 0.444 0.000
M17.3 Other posttraumatic gonarthrosis
0.556 0.444 0.000
Z50.0 Cardiac rehabilitation
0.556 0.444 0.000
S65 Injury of blood vessels at wrist and hand level
0.556 0.444 0.000
M07 Psoriatic and enteropathic arthropathies
0.556 0.444 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.555 0.444 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.555 0.445 0.000
K50-K52 Noninfective enteritis and colitis
0.554 0.446 0.000
M16.5 Other posttraumatic coxarthrosis
0.554 0.446 0.000
K29.8 Duodenitis
0.554 0.446 0.000
L50-L54 Urticaria and erythema
0.554 0.446 0.000
S89 Other and unspecified injuries of lower leg
0.553 0.446 0.000
Z96 Presence of other functional implants
0.554 0.446 0.000
A30-A49 Other bacterial diseases
0.553 0.447 0.000
N95.1 Menopausal and female climacteric states
0.553 0.447 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.553 0.447 0.000
B25-B34 Other viral diseases
0.552 0.448 0.000
I42.4 Endocardial fibroelastosis
0.552 0.448 0.000
I42.5 Other restrictive cardiomyopathy
0.552 0.448 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.552 0.448 0.000
K25 Gastric ulcer
0.551 0.449 0.000
I77.8 Other specified disorders of arteries and arterioles
0.551 0.449 0.000
K74 Fibrosis and cirrhosis of liver
0.551 0.449 0.000
N87.1 Moderate cervical dysplasia
0.551 0.449 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.551 0.449 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.551 0.449 0.000
M06.9 Rheumatoid arthritis, unspecified
0.550 0.450 0.000
R87.6 Abnormal cytological findings
0.550 0.450 0.000
M22 Disorders of patella
0.550 0.450 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.550 0.450 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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