TreeWAS – Variant ID: rs2728124

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C90.0 Multiple myeloma	0.098	0.902	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.076	0.924	0.000
C90.2 Plasmacytoma, extramedullary	0.070	0.930	0.000
C90.1 Plasma cell leukaemia	0.063	0.937	0.000
O32.1 Maternal care for breech presentation	0.054	0.946	0.000
C90.3 Solitary plasmacytoma	0.049	0.951	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.045	0.955	0.000
O32.4 Maternal care for high head at term	0.039	0.961	0.000
O32.8 Maternal care for other malpresentation of foetus	0.039	0.961	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.037	0.963	0.000
O32.0 Maternal care for unstable lie	0.034	0.966	0.000
O32.6 Maternal care for compound presentation	0.034	0.966	0.000
O32.2 Maternal care for transverse and oblique lie	0.032	0.968	0.000
K56.2 Volvulus	0.032	0.968	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.031	0.969	0.000
O32.3 Maternal care for face, brow and chin presentation	0.027	0.973	0.000
I07.1 Tricuspid insufficiency	0.013	0.987	0.000
Z03.3 Observation for suspected nervous system disorder	0.012	0.988	0.000
I05.9 Mitral valve disease, unspecified	0.011	0.989	0.000
I05 Rheumatic mitral valve diseases	0.011	0.989	0.000
I07 Rheumatic tricuspid valve diseases	0.011	0.989	0.000
I05.2 Mitral stenosis with insufficiency	0.010	0.990	0.000
I05.1 Rheumatic mitral insufficiency	0.009	0.990	0.000
I05-I09 Chronic rheumatic heart diseases	0.009	0.991	0.000
I05.0 Mitral stenosis	0.008	0.992	0.000
I05.8 Other mitral valve diseases	0.008	0.992	0.000
I07.9 Tricuspid valve disease, unspecified	0.008	0.992	0.000
I07.8 Other tricuspid valve diseases	0.008	0.992	0.000
I07.2 Tricuspid stenosis with insufficiency	0.008	0.992	0.000
I07.0 Tricuspid stenosis	0.008	0.992	0.000
D68.8 Other specified coagulation defects	0.007	0.993	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.007	0.993	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.007	0.993	0.000
I09 Other rheumatic heart diseases	0.007	0.993	0.000
I61 Intracerebral haemorrhage	0.007	0.993	0.000
C83.0 Small cell (diffuse)	0.007	0.993	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.007	0.993	0.000
O70.2 Third degree perineal laceration during delivery	0.007	0.993	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.007	0.993	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.006	0.993	0.000
H61.2 Impacted cerumen	0.000	0.994	0.006
I61.6 Intracerebral haemorrhage, multiple localised	0.006	0.994	0.000
O70.0 First degree perineal laceration during delivery	0.006	0.994	0.000
K56.4 Other impaction of intestine	0.006	0.994	0.000
C81 Hodgkin's disease	0.006	0.994	0.000
I09.9 Rheumatic heart disease, unspecified	0.006	0.994	0.000
I61.8 Other intracerebral haemorrhage	0.006	0.994	0.000
C94 Other leukaemias of specified cell type	0.006	0.994	0.000
C83.1 Small cleaved cell (diffuse)	0.006	0.994	0.000
D68.1 Hereditary factor XI deficiency	0.006	0.994	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.006	0.994	0.000
D68.6 Other Thrombophilia	0.006	0.994	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.006	0.994	0.000
D68 Other coagulation defects	0.006	0.994	0.000
I06 Rheumatic aortic valve diseases	0.006	0.994	0.000
C71.8 Overlapping lesion of brain	0.000	0.994	0.006
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.005	0.994	0.000
C71 Malignant neoplasm of brain	0.000	0.995	0.005
C86 Other specified types of T/NK-cell lymphoma	0.005	0.995	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.005	0.995	0.000
I09.8 Other specified rheumatic heart diseases	0.005	0.995	0.000
I09.2 Chronic rheumatic pericarditis	0.005	0.995	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.005	0.995	0.000
I09.0 Rheumatic myocarditis	0.005	0.995	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.995	0.005
C83.5 Lymphoblastic (diffuse)	0.005	0.995	0.000
H61.1 Non-infective disorders of pinna	0.000	0.995	0.005
C94.4 Acute panmyelosis	0.005	0.995	0.000
C81.2 Mixed cellularity	0.005	0.995	0.000
D68.9 Coagulation defect, unspecified	0.005	0.995	0.000
C81.9 Hodgkin's disease, unspecified	0.005	0.995	0.000
C93 Monocytic leukaemia	0.005	0.995	0.000
C83.6 Undifferentiated (diffuse)	0.005	0.995	0.000
C83.4 Immunoblastic (diffuse)	0.005	0.995	0.000
C83.2 Mixed small and large cell (diffuse)	0.005	0.995	0.000
C71.9 Brain, unspecified	0.000	0.995	0.005
C71.3 Parietal lobe	0.000	0.995	0.005
K56 Paralytic ileus and intestinal obstruction without hernia	0.005	0.995	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.005	0.995	0.000
D68.5 Primary Thrombophilia	0.005	0.995	0.000
C81.1 Nodular sclerosis	0.005	0.995	0.000
C81.7 Other Hodgkin's disease	0.005	0.995	0.000
C83.7 Burkitt's tumour	0.005	0.995	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.995	0.005
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.005	0.995	0.000
C81.3 Lymphocytic depletion	0.005	0.995	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.005	0.995	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.005	0.995	0.000
C94.7 Other specified leukaemias	0.004	0.995	0.000
C94.5 Acute myelofibrosis	0.004	0.995	0.000
C94.3 Mast cell leukaemia	0.004	0.995	0.000
C94.2 Acute megakaryoblastic leukaemia	0.004	0.995	0.000
C94.1 Chronic erythraemia	0.004	0.995	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.004	0.995	0.000
I06.1 Rheumatic aortic insufficiency	0.004	0.995	0.000
H53.4 Visual field defects	0.005	0.995	0.000
C81.0 Lymphocytic predominance	0.004	0.995	0.000
C88 Malignant immunoproliferative diseases	0.004	0.995	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.995	0.005
C71.1 Frontal lobe	0.000	0.995	0.004
K65.8 Other peritonitis	0.004	0.996	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.004	0.996	0.000
I06.8 Other rheumatic aortic valve diseases	0.004	0.996	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.004	0.996	0.000
H61 Other disorders of external ear	0.000	0.996	0.004
C84 Peripheral and cutaneous T-cell lymphomas	0.004	0.996	0.000
C71.4 Occipital lobe	0.000	0.996	0.004
D68.4 Acquired coagulation factor deficiency	0.004	0.996	0.000
D69.6 Thrombocytopenia, unspecified	0.004	0.996	0.000
C95 Leukaemia of unspecified cell type	0.004	0.996	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.004	0.996	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.996	0.004
C71.5 Cerebral ventricle	0.000	0.996	0.004
C71.7 Brain stem	0.000	0.996	0.004
C71.6 Cerebellum	0.000	0.996	0.004
C86.5 Angioimmunoblastic T-cell lymphoma	0.004	0.996	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.004	0.996	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.004	0.996	0.000
C86.4 Blastic NK-cell lymphoma	0.004	0.996	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.004	0.996	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.004	0.996	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.004	0.996	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.004	0.996	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.004	0.996	0.000
C96.8 Histiocytic sarcoma	0.004	0.996	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.004	0.996	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.004	0.996	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.004	0.996	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.004	0.996	0.000
C96.3 True histiocytic lymphoma	0.004	0.996	0.000
C96.2 Malignant mast cell tumour	0.004	0.996	0.000
C96.1 Malignant histiocytosis	0.004	0.996	0.000
C96.0 Letterer-Siwe disease	0.004	0.996	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.996	0.004
C85.0 Lymphosarcoma	0.004	0.996	0.000
C92 Myeloid leukaemia	0.004	0.996	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.004	0.996	0.000
C93.9 Monocytic leukaemia, unspecified	0.004	0.996	0.000
C93.7 Other monocytic leukaemia	0.004	0.996	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.004	0.996	0.000
C93.2 Subacute monocytic leukaemia	0.004	0.996	0.000
C93.0 Acute monocytic leukaemia	0.004	0.996	0.000
D69 Purpura and other haemorrhagic conditions	0.004	0.996	0.000
O70 Perineal laceration during delivery	0.004	0.996	0.000
T85.2 Mechanical complication of intraocular lens	0.000	0.996	0.004
C71.2 Temporal lobe	0.000	0.996	0.004
K56.5 Intestinal adhesions [bands] with obstruction	0.004	0.996	0.000
O20.0 Threatened abortion	0.004	0.996	0.000
H92.0 Otalgia	0.000	0.996	0.004
Z80.3 Family history of malignant neoplasm of breast	0.000	0.996	0.004
C88.9 Malignant immunoproliferative disease, unspecified	0.003	0.996	0.000
C88.7 Other malignant immunoproliferative diseases	0.003	0.996	0.000
C88.3 Immunoproliferative small intestinal disease	0.003	0.996	0.000
C88.2 Gamma heavy chain disease	0.003	0.996	0.000
C88.1 Alpha heavy chain disease	0.003	0.996	0.000
I06.0 Rheumatic aortic stenosis	0.003	0.996	0.000
C91 Lymphoid leukaemia	0.004	0.996	0.000
C93.1 Chronic monocytic leukaemia	0.003	0.997	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.003	0.997	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.003	0.997	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.003	0.997	0.000
C84.3 Lymphoepithelioid lymphoma	0.003	0.997	0.000
C84.2 T-zone lymphoma	0.003	0.997	0.000
C84.1 Sezary's diease	0.003	0.997	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.003	0.997	0.000
C84.4 Peripheral T-cell lymphoma	0.003	0.997	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.003	0.997	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.003	0.997	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.003	0.997	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.003	0.997	0.000
C95.7 Other leukaemia of unspecified cell type	0.003	0.997	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.003	0.997	0.000
C92.9 Myeloid leukaemia, unspecified	0.003	0.997	0.000
R44.0 Auditory hallucinations	0.003	0.997	0.000
Z80.5 Family history of malignant neoplasm of urinary tract	0.000	0.997	0.003
C84.0 Mycosis fungoides	0.003	0.997	0.000
C95.0 Acute leukaemia of unspecified cell type	0.003	0.997	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.003	0.997	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.003	0.997	0.000
H50.1 Divergent concomitant strabismus	0.003	0.997	0.000
C85.1 B-cell lymphoma, unspecified	0.003	0.997	0.000
D69.1 Qualitative platelet defects	0.003	0.997	0.000
K56.3 Gallstone ileus	0.003	0.997	0.000
Y84.1 Kidney dialysis	0.003	0.997	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.003	0.997	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.003	0.997	0.000
C92.3 Myeloid sarcoma	0.003	0.997	0.000
C92.2 Subacute myeloid leukaemia	0.003	0.997	0.000
D68.0 Von Willebrand's disease	0.003	0.997	0.000
K56.7 Ileus, unspecified	0.003	0.997	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.997	0.003
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.003	0.997	0.000
D69.9 Haemorrhagic condition, unspecified	0.003	0.997	0.000
D69.2 Other nonthrombocytopenic purpura	0.003	0.997	0.000
C84.5 Other and unspecified T-cell lymphomas	0.003	0.997	0.000
C91.5 Adult T-cell leukaemia	0.003	0.997	0.000
D69.8 Other specified haemorrhagic conditions	0.003	0.997	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.003	0.997	0.000
C92.5 Acute myelomonocytic leukaemia	0.003	0.997	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.000	0.997	0.003
D67 Hereditary factor IX deficiency	0.003	0.997	0.000
D69.4 Other primary thrombocytopenia	0.003	0.997	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
O70.3 Fourth degree perineal laceration during delivery	0.003	0.997	0.000
C92.0 Acute myeloid leukaemia	0.003	0.997	0.000
H61.8 Other specified disorders of external ear	0.000	0.997	0.003
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.003	0.997	0.000
C91.9 Lymphoid leukaemia, unspecified	0.003	0.997	0.000
K65 Peritonitis	0.003	0.997	0.000
D66 Hereditary factor VIII deficiency	0.003	0.997	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.003	0.997	0.000
C91.7 Other lymphoid leukaemia	0.003	0.997	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.003	0.997	0.000
C91.3 Prolymphocytic leukaemia	0.003	0.997	0.000
C91.2 Subacute lymphocytic leukaemia	0.003	0.997	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.997	0.003
C92.4 Acute promyelocytic leukaemia	0.003	0.997	0.000
N05.9 Unspecified	0.003	0.997	0.000
K65.9 Peritonitis, unspecified	0.003	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.003	0.997	0.000
O20 Haemorrhage in early pregnancy	0.003	0.997	0.000
Z80 Family history of malignant neoplasm	0.000	0.997	0.003
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.003	0.997	0.000
C92.1 Chronic myeloid leukaemia	0.003	0.997	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.003	0.997	0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.997	0.003
C91.0 Acute lymphoblastic leukaemia	0.003	0.997	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.997	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.003	0.997	0.000
C91.4 Hairy-cell leukaemia	0.002	0.997	0.000
C92.7 Other myeloid leukaemia	0.002	0.998	0.000
Z36.9 Antenatal screening, unspecified	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
Z80.6 Family history of leukaemia	0.000	0.998	0.002
C95.9 Leukaemia, unspecified	0.002	0.998	0.001
C73 Malignant neoplasm of thyroid gland	0.000	0.998	0.002
D69.5 Secondary thrombocytopenia	0.002	0.998	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.002	0.998	0.000
K56.0 Paralytic ileus	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
H31.0 Chorioretinal scars	0.002	0.998	0.000
S00.9 Superficial injury of head, part unspecified	0.002	0.998	0.000
E29.1 Testicular hypofunction	0.000	0.998	0.002
H61.9 Disorder of external ear, unspecified	0.000	0.998	0.002
S62.20 Fracture of first metacarpal bone (closed)	0.002	0.998	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.002	0.998	0.000
C82.0 Small cleaved cell, follicular	0.002	0.998	0.000
K65.0 Acute peritonitis	0.002	0.998	0.000
I08 Multiple valve diseases	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
K63.3 Ulcer of intestine	0.002	0.998	0.000
N05.8 Other	0.002	0.998	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.998	0.002
V18.0 Driver injured in nontraffic accident	0.002	0.998	0.000
D69.0 Allergic purpura	0.002	0.998	0.000
C82.6 Cutaneous follicle centre lymphoma	0.002	0.998	0.000
C82.5 Diffuse follicle centre lymphoma	0.002	0.998	0.000
D56.1 Beta thalassaemia	0.002	0.998	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.998	0.002
Z39.0 Care and examination immediately after delivery	0.002	0.998	0.000
R44.1 Visual hallucinations	0.002	0.998	0.000
A48.1 Legionnaires' disease	0.000	0.998	0.002
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.002	0.998	0.000
I67.2 Cerebral atherosclerosis	0.002	0.998	0.000
N84.2 Polyp of vagina	0.002	0.998	0.000
C82.4 Follicular lymphoma grade IIIb	0.002	0.998	0.000
E85.9 Amyloidosis, unspecified	0.002	0.998	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.002	0.998	0.000
D56.3 Thalassaemia trait	0.002	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.000	0.998	0.002
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.000	0.998	0.002
D25.1 Intramural leiomyoma of uterus	0.002	0.998	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.002	0.998	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.998	0.002
N05 Unspecified nephritic syndrome	0.002	0.998	0.000
D56 Thalassaemia	0.002	0.998	0.000
C82.2 Large cell, follicular	0.002	0.998	0.000
H92 Otalgia and effusion of ear	0.000	0.998	0.002
A08.4 Viral intestinal infection, unspecified	0.002	0.998	0.000
Z50.5 Speech therapy	0.000	0.998	0.002
K63.2 Fistula of intestine	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.000	0.998	0.002
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.998	0.002
H90.3 Sensorineural hearing loss, bilateral	0.000	0.998	0.002
I08.0 Disorders of both mitral and aortic valves	0.002	0.998	0.000
K56.1 Intussusception	0.001	0.998	0.000
I12 Hypertensive renal disease	0.000	0.998	0.002
R22.1 Localised swelling, mass and lump, neck	0.000	0.998	0.002
R44.2 Other hallucinations	0.002	0.998	0.000
W22.9 Unspecified place	0.000	0.998	0.002
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
C82.3 Follicular lymphoma grade IIIa	0.001	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.002	0.998	0.000
O70.9 Perineal laceration during delivery, unspecified	0.001	0.998	0.001
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.002	0.998	0.000
I72.0 Aneurysm of carotid artery	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M25.71 Osteophyte (Shoulder region)	0.002	0.998	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.002	0.998	0.000
V18.1 Passenger injured in nontraffic accident	0.002	0.998	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.002	0.998	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.002	0.998	0.000
I08.9 Multiple valve disease, unspecified	0.001	0.998	0.000
N05.6 Dense deposit disease	0.001	0.998	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.998	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.998	0.000
N05.2 Diffuse membranous glomerulonephritis	0.001	0.998	0.000
N05.0 Minor glomerular abnormality	0.001	0.998	0.000
T23.3 Burn of third degree of wrist and hand	0.000	0.998	0.002
D56.9 Thalassaemia, unspecified	0.001	0.998	0.000
D56.8 Other thalassaemias	0.001	0.998	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.001	0.998	0.000
D56.2 Delta-beta thalassaemia	0.001	0.998	0.000
D56.0 Alpha thalassaemia	0.001	0.998	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.001	0.998	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.001	0.998	0.000
I72.3 Aneurysm of iliac artery	0.002	0.998	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.998	0.002
D82 Immunodeficiency associated with other major defects	0.001	0.998	0.000
I72 Other aneurysm	0.002	0.998	0.000
M25.78 Osteophyte (Other)	0.000	0.998	0.002
H92.2 Otorrhagia	0.000	0.998	0.001
I12.9 Hypertensive renal disease without renal failure	0.000	0.998	0.001
I22.9 Subsequent myocardial infarction of unspecified site	0.002	0.998	0.000
Z36 Antenatal screening	0.002	0.998	0.000
I72.9 Aneurysm of unspecified site	0.001	0.999	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.999	0.000
E88.8 Other specified metabolic disorders	0.000	0.999	0.001
R86.8 Other abnormal findings	0.001	0.999	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.001	0.999	0.000
D82.1 Di George's syndrome	0.001	0.999	0.000
N05.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
D84 Other immunodeficiencies	0.001	0.999	0.000
D81 Combined immunodeficiencies	0.001	0.999	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.001	0.999	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.001	0.999	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.001	0.999	0.000
Z39.2 Routine postpartum follow-up	0.001	0.999	0.000
I27.8 Other specified pulmonary heart diseases	0.001	0.999	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.001	0.999	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
V18.9 Unspecified pedal cyclist injured in traffic accident	0.001	0.999	0.000
V18.4 Driver injured in traffic accident	0.001	0.999	0.000
V18.3 Person injured while boarding or alighting	0.001	0.999	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.001	0.999	0.000
Y87.1 Sequelae of assault	0.001	0.999	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.001	0.999	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.999	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.999	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.999	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.999	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.999	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.000
H92.1 Otorrhoea	0.000	0.999	0.001
I72.6 Aneurysm and dissection of vertebral artery	0.001	0.999	0.000
I72.2 Aneurysm of renal artery	0.001	0.999	0.000
N25.0 Renal osteodystrophy	0.001	0.999	0.000
Z36.5 Antenatal screening for isoimmunisation	0.001	0.999	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.999	0.001
I22.8 Subsequent myocardial infarction of other sites	0.001	0.999	0.000
V18.5 Passenger injured in traffic accident	0.001	0.999	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.999	0.001
D84.9 Immunodeficiency, unspecified	0.001	0.999	0.000
D84.8 Other specified immunodeficiencies	0.001	0.999	0.000
H31.3 Choroidal haemorrhage and rupture	0.001	0.999	0.000
R44.3 Hallucinations, unspecified	0.001	0.999	0.000
E88 Other metabolic disorders	0.000	0.999	0.001
N25 Disorders resulting from impaired renal tubular function	0.001	0.999	0.000
M54.36 Sciatica (Lumbar region)	0.001	0.999	0.000
M76.87 Other enthesopathies of lower limb, excluding foot (Ankle and foot)	0.001	0.999	0.000
H31.1 Choroidal degeneration	0.001	0.999	0.000
H54.4 Blindness, one eye	0.000	0.999	0.001
I72.1 Aneurysm of artery of upper extremity	0.001	0.999	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.000
T23.1 Burn of first degree of wrist and hand	0.000	0.999	0.001
Z46.8 Fitting and adjustment of other specified devices	0.000	0.999	0.001
M76.66 Achilles tendinitis (Lower leg)	0.001	0.999	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.001	0.999	0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.001	0.999	0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.001	0.999	0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.001	0.999	0.000
N25.1 Nephrogenic diabetes insipidus	0.001	0.999	0.000
Y57.9 Drug or medicament, unspecified	0.001	0.999	0.000
H31 Other disorders of choroid	0.001	0.999	0.000
S73.0 Dislocation of hip	0.000	0.999	0.001
T23.2 Burn of second degree of wrist and hand	0.000	0.999	0.001
Z39 Postpartum care and examination	0.001	0.999	0.000
M40.24 Other and unspecified kyphosis (Thoracic region)	0.000	0.999	0.001
M60.89 Other myositis (Site unspecified)	0.001	0.999	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.999	0.001
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.999	0.001
Q82.8 Other specified congenital malformations of skin	0.000	0.999	0.001
D51 Vitamin B12 deficiency anaemia	0.001	0.999	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.999	0.001
D55-D59 Haemolytic anaemias	0.001	0.999	0.000
H60-H62 Diseases of external ear	0.000	0.999	0.001
H31.9 Disorder of choroid, unspecified	0.001	0.999	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.001	0.999	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.000	0.999	0.001
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.001	0.999	0.000
M76.67 Achilles tendinitis (Ankle and foot)	0.001	0.999	0.000
E85.4 Organ-limited amyloidosis	0.001	0.999	0.000
T23 Burn and corrosion of wrist and hand	0.000	0.999	0.001
D84.1 Defects in the complement system	0.001	0.999	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.999	0.001
E27.2 Addisonian crisis	0.001	0.999	0.000
E88.9 Metabolic disorder, unspecified	0.000	0.999	0.001
H31.4 Choroidal detachment	0.001	0.999	0.000
H31.2 Hereditary choroidal dystrophy	0.001	0.999	0.000
I34.1 Mitral (valve) prolapse	0.001	0.999	0.000
S62.2 Fracture of first metacarpal bone	0.001	0.999	0.000
S20 Superficial injury of thorax	0.000	0.999	0.001
C09.9 Tonsil, unspecified	0.000	0.999	0.001
D68.2 Hereditary deficiency of other clotting factors	0.001	0.999	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.001	0.999	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.001	0.999	0.000
S01.2 Open wound of nose	0.001	0.999	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.999	0.001
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.001	0.999	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.001	0.999	0.000
D51.2 Transcobalamin II deficiency	0.001	0.999	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.001	0.999	0.000
D53.9 Nutritional anaemia, unspecified	0.001	0.999	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.999	0.001
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.999	0.001
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
H62.2 Otitis externa in mycoses	0.000	0.999	0.001
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.999	0.001
J34.1 Cyst and mucocele of nose and nasal sinus	0.001	0.999	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.000	0.999	0.001
D55 Anaemia due to enzyme disorders	0.001	0.999	0.000
M60.24 Foreign body granuloma of soft tissue, not elsewhere classified (Hand)	0.001	0.999	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.001	0.999	0.000
C74.9 Adrenal gland, unspecified	0.000	0.999	0.001
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.001	0.999	0.000
I27.9 Pulmonary heart disease, unspecified	0.001	0.999	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.001	0.999	0.000
K62.9 Disease of anus and rectum, unspecified	0.001	0.999	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.000	0.999	0.001
S20.4 Other superficial injuries of back wall of thorax	0.000	0.999	0.001
T23.7 Corrosion of third degree of wrist and hand	0.000	0.999	0.001
T23.6 Corrosion of second degree of wrist and hand	0.000	0.999	0.001
T23.5 Corrosion of first degree of wrist and hand	0.000	0.999	0.001
T23.4 Corrosion of unspecified degree of wrist and hand	0.000	0.999	0.001
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.999	0.001
M60.95 Myositis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.000	0.999	0.001
S62.21 Fracture of first metacarpal bone (open)	0.001	0.999	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.999	0.001
N17.0 Acute renal failure with tubular necrosis	0.001	0.999	0.000
N34.2 Other urethritis	0.001	0.999	0.000
S20.7 Multiple superficial injuries of thorax	0.000	0.999	0.001
S51.0 Open wound of elbow	0.000	0.999	0.001
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.001	0.999	0.000
D57 Sickle-cell disorders	0.001	0.999	0.000
Q82 Other congenital malformations of skin	0.000	0.999	0.001
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.001	0.999	0.000
D33.3 Cranial nerves	0.000	0.999	0.001
D55.9 Anaemia due to enzyme disorder, unspecified	0.001	0.999	0.000
D55.8 Other anaemias due to enzyme disorders	0.001	0.999	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.001	0.999	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.001	0.999	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.001	0.999	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.001	0.999	0.000
E88.3 Tumour lysis syndrome	0.000	0.999	0.001
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.999	0.001
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.001	0.999	0.000
S20.1 Other and unspecified superficial injuries of breast	0.000	0.999	0.001
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.001	0.999	0.000
C18.5 Splenic flexure	0.000	0.999	0.001
V17.4 Driver injured in traffic accident	0.001	0.999	0.000
Z31.4 Procreative investigation and testing	0.001	0.999	0.000
Z76.3 Healthy person accompanying sick person	0.000	0.999	0.001
E85 Amyloidosis	0.001	0.999	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.001	0.999	0.000
D57.8 Other sickle-cell disorders	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations