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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2736155
log Bayes Factor = 138.53
Chromosome 6   position 31,605,199  (GRCh37) Explore rs2736155 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E10.2 With renal complications
0.000 0.005 0.995
E10.1 With ketoacidosis
0.000 0.006 0.994
I10 Essential (primary) hypertension
0.993 0.007 0.000
K90 Intestinal malabsorption
0.000 0.014 0.986
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.019 0.981
E50-E64 Other nutritional deficiencies
0.000 0.026 0.974
K90.9 Intestinal malabsorption, unspecified
0.000 0.027 0.973
E16 Other disorders of pancreatic internal secretion
0.000 0.032 0.968
E14 Unspecified diabetes mellitus
0.000 0.048 0.952
E16.2 Hypoglycaemia, unspecified
0.000 0.050 0.950
E53 Deficiency of other B group vitamins
0.000 0.058 0.942
E10.4 With neurological complications
0.000 0.058 0.942
E10.5 With peripheral circulatory complications
0.000 0.087 0.913
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.099 0.901
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.115 0.885
E53.8 Deficiency of other specified B group vitamins
0.000 0.122 0.878
E14.3 With ophthalmic complications
0.000 0.125 0.875
E10.0 With coma
0.000 0.133 0.867
E06 Thyroiditis
0.000 0.144 0.856
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.147 0.853
E53.9 Vitamin B deficiency, unspecified
0.000 0.152 0.848
L40.9 Psoriasis, unspecified
0.845 0.155 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.838 0.162 0.000
E55 Vitamin D deficiency
0.000 0.168 0.832
G37 Other demyelinating diseases of central nervous system
0.000 0.176 0.824
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.179 0.821
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.819 0.181 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.819 0.181 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.818 0.182 0.000
T39.1 4-Aminophenol derivatives
0.812 0.188 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.807 0.193 0.000
E14.6 With other specified complications
0.000 0.196 0.804
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.796 0.204 0.000
K90.8 Other intestinal malabsorption
0.000 0.230 0.770
E14.2 Withrenal complications
0.000 0.232 0.768
T43.5 Other and unspecified antipsychotics and neuroleptics
0.765 0.235 0.000
E14.8 With unspecified complications
0.000 0.242 0.758
E14.1 With ketoacidosis
0.000 0.243 0.757
E06.9 Thyroiditis, unspecified
0.000 0.247 0.753
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.753 0.247 0.000
R31 Unspecified haematuria
0.750 0.250 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.254 0.746
T43.2 Other and unspecified antidepressants
0.746 0.254 0.000
E14.5 With peripheral circulatory complications
0.000 0.256 0.744
E10.7 With multiple complications
0.000 0.259 0.740
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.739 0.261 0.000
E40-E46 Malnutrition
0.000 0.261 0.739
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.733 0.267 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.269 0.731
E51 Thiamine deficiency
0.000 0.272 0.727
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.278 0.722
E61 Deficiency of other nutrient elements
0.000 0.279 0.721
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E13 Other specified diabetes mellitus
0.000 0.284 0.716
T46.4 Angiotensin-converting-enzyme inhibitors
0.715 0.285 0.000
E58 Dietary calcium deficiency
0.000 0.286 0.714
E10.6 With other specified complications
0.000 0.292 0.708
K90.3 Pancreatic steatorrhoea
0.000 0.293 0.707
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.293 0.707
K90.1 Tropical sprue
0.000 0.293 0.707
T39.0 Salicylates
0.707 0.293 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.296 0.704
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.698 0.302 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.302 0.698
E63 Other nutritional deficiencies
0.000 0.302 0.698
E50 Vitamin A deficiency
0.000 0.302 0.698
E60 Dietary zinc deficiency
0.000 0.302 0.698
E59 Dietary selenium deficiency
0.000 0.302 0.698
E52 Niacin deficiency [pellagra]
0.000 0.302 0.698
E05.8 Other thyrotoxicosis
0.000 0.303 0.697
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.306 0.694
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.306 0.694
E16.4 Abnormal secretion of gastrin
0.000 0.306 0.694
E16.3 Increased secretion of glucagon
0.000 0.306 0.694
D25.9 Leiomyoma of uterus, unspecified
0.690 0.310 0.000
E14.4 With neurological complications
0.000 0.310 0.690
E14.7 With multiple complications
0.000 0.317 0.683
E14.0 With coma
0.000 0.317 0.683
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.323 0.677
E78.0 Pure hypercholesterolaemia
0.677 0.323 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.677 0.323 0.000
E53.1 Pyridoxine deficiency
0.000 0.324 0.675
E53.0 Riboflavin deficiency
0.000 0.324 0.675
T50.9 Other and unspecified drugs, medicaments and biological substances
0.673 0.327 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.664 0.336 0.000
E06.3 Autoimmune thyroiditis
0.000 0.336 0.664
T46.5 Other antihypertensive drugs, not elsewhere classified
0.649 0.351 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.647 0.353 0.000
E54 Ascorbic acid deficiency
0.000 0.357 0.643
E56 Other vitamin deficiencies
0.000 0.364 0.636
E61.2 Magnesium deficiency
0.000 0.370 0.630
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.617 0.383 0.000
T45.0 Antiallergic and antiemetic drugs
0.616 0.384 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.615 0.385 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.614 0.386 0.000
E06.4 Drug-induced thyroiditis
0.000 0.386 0.614
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.386 0.614
E06.0 Acute thyroiditis
0.000 0.386 0.614
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.608 0.392 0.000
G36 Other acute disseminated demyelination
0.000 0.393 0.607
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.607 0.393 0.000
E06.5 Other chronic thyroiditis
0.000 0.395 0.605
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.604 0.396 0.000
T43.6 Psychostimulants with abuse potential
0.601 0.399 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.601 0.399 0.000
E10.8 With unspecified complications
0.000 0.400 0.600
E55.0 Rickets, active
0.000 0.403 0.597
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.593 0.406 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.409 0.590
G37.4 Subacute necrotising myelitis
0.000 0.409 0.590
G37.2 Central pontine myelinolysis
0.000 0.409 0.590
G37.1 Central demyelination of corpus callosum
0.000 0.409 0.590
G37.0 Diffuse sclerosis
0.000 0.409 0.590
E11 Non-insulin-dependent diabetes mellitus
0.000 0.412 0.588
T43.9 Psychotropic drug, unspecified
0.587 0.412 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.587 0.412 0.000
T39.4 Antirheumatics, not elsewhere classified
0.587 0.413 0.000
T39.2 Pyrazolone derivatives
0.587 0.413 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.587 0.413 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.587 0.413 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.587 0.413 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.587 0.413 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.587 0.413 0.000
T44.0 Anticholinesterase agents
0.587 0.413 0.000
T50.4 Drugs affecting uric acid metabolism
0.586 0.414 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.583 0.417 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.582 0.418 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.578 0.422 0.000
T46.7 Peripheral vasodilators
0.578 0.422 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.424 0.576
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.571 0.429 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.571 0.429 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.570 0.430 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.569 0.431 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.568 0.432 0.000
E06.1 Subacute thyroiditis
0.000 0.437 0.563
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.556 0.443 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.448 0.551
E51.2 Wernicke's encephalopathy
0.000 0.449 0.551
T36 Poisoning by systemic antibiotics
0.546 0.454 0.000
T50.7 Analeptics and opioid receptor antagonists
0.540 0.460 0.000
T50.5 Appetite depressants
0.540 0.460 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.540 0.460 0.000
T50.1 Loop [high-ceiling] diuretics
0.540 0.460 0.000
T50.0 Mineralocorticoids and their antagonists
0.540 0.460 0.000
T38.1 Thyroid hormones and substitutes
0.535 0.465 0.000
E13.9 Without complications
0.000 0.466 0.534
T43.0 Tricyclic and tetracyclic antidepressants
0.531 0.469 0.000
T38.0 Glucocorticoids and synthetic analogues
0.531 0.469 0.000
E11.5 With peripheral circulatory complications
0.000 0.470 0.530
T38.9 Other and unspecified hormone antagonists
0.530 0.470 0.000
T38.7 Androgens and anabolic congeners
0.530 0.470 0.000
T38.5 Other oestrogens and progestogens
0.530 0.470 0.000
T38.4 Oral contraceptives
0.530 0.470 0.000
T38.2 Antithyroid drugs
0.530 0.470 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.470 0.530
E45 Retarded development following protein-energy malnutrition
0.000 0.470 0.530
E43 Unspecified severe protein-energy malnutrition
0.000 0.470 0.530
E42 Marasmic kwashiorkor
0.000 0.470 0.530
E41 Nutritional marasmus
0.000 0.470 0.530
E40 Kwashiorkor
0.000 0.470 0.530
T43.4 Butyrophenone and thioxanthene neuroleptics
0.525 0.475 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.478 0.522
E51.8 Other manifestations of thiamine deficiency
0.000 0.478 0.522
E51.1 Beriberi
0.000 0.478 0.522
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.521 0.479 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.483 0.517
E61.8 Deficiency of other specified nutrient elements
0.000 0.483 0.517
E61.7 Deficiency of multiple nutrient elements
0.000 0.483 0.517
E61.6 Vanadium deficiency
0.000 0.483 0.517
E61.5 Molybdenum deficiency
0.000 0.483 0.517
E61.4 Chromium deficiency
0.000 0.483 0.517
E61.3 Manganese deficiency
0.000 0.483 0.517
E61.0 Copper deficiency
0.000 0.483 0.517
E27.1 Primary adrenocortical insufficiency
0.000 0.483 0.517
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E13.8 With unspecified complications
0.000 0.486 0.513
E13.7 With multiple complications
0.000 0.486 0.513
E13.6 With other specified complications
0.000 0.486 0.513
E13.5 With peripheral circulatory complications
0.000 0.486 0.513
E13.4 With neurological complications
0.000 0.486 0.513
E13.2 With renal complications
0.000 0.486 0.513
E13.1 With ketoacidosis
0.000 0.486 0.513
E13.0 With coma
0.000 0.486 0.513
E16.1 Other hypoglycaemia
0.000 0.487 0.513
E11.4 With neurological complications
0.000 0.487 0.513
T46.1 Calcium-channel blockers
0.503 0.497 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.501 0.499 0.000
T45.8 Other primarily systemic and haematological agents
0.501 0.499 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.501 0.499 0.000
T45.6 Fibrinolysis-affecting drugs
0.501 0.499 0.000
T45.4 Iron and its compounds
0.501 0.499 0.000
T45.3 Enzymes, not elsewhere classified
0.501 0.499 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.499 0.501
E50.8 Other manifestations of vitamin A deficiency
0.000 0.499 0.501
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.499 0.501
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.499 0.501
E50.5 Vitamin A deficiency with night blindness
0.000 0.499 0.501
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.499 0.501
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.499 0.501
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.499 0.501
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.499 0.501
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.499 0.501
E63.9 Nutritional deficiency, unspecified
0.000 0.499 0.501
E63.8 Other specified nutritional deficiencies
0.000 0.499 0.501
E63.1 Imbalance of constituents of food intake
0.000 0.499 0.501
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.499 0.501
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.499 0.501
E64.8 Sequelae of other nutritional deficiencies
0.000 0.499 0.501
E64.3 Sequelae of rickets
0.000 0.499 0.501
E64.2 Sequelae of vitamin C deficiency
0.000 0.499 0.501
E64.1 Sequelae of vitamin A deficiency
0.000 0.499 0.501
E64.0 Sequelae of protein-energy malnutrition
0.000 0.499 0.501
T45.1 Antineoplastic and immunosuppressive drugs
0.495 0.504 0.000
T45.5 Anticoagulants
0.494 0.505 0.000
E13.3 With ophthalmic complications
0.000 0.510 0.490
T46.3 Coronary vasodilators, not elsewhere classified
0.489 0.511 0.000
E27 Other disorders of adrenal gland
0.000 0.519 0.481
E20-E35 Disorders of other endocrine glands
0.000 0.520 0.480
T37.2 Antimalarials and drugs acting on other blood protozoa
0.480 0.520 0.000
T50.8 Diagnostic agents
0.476 0.523 0.000
T45.2 Vitamins, not elsewhere classified
0.472 0.528 0.000
R04.0 Epistaxis
0.462 0.538 0.000
E11.0 With coma
0.000 0.540 0.460
E56.9 Vitamin deficiency, unspecified
0.000 0.544 0.456
E56.8 Deficiency of other vitamins
0.000 0.544 0.456
E56.0 Deficiency of vitamin E
0.000 0.544 0.456
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.449 0.551 0.000
T42.0 Hydantoin derivatives
0.447 0.553 0.000
T42.3 Barbiturates
0.445 0.555 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.441 0.559 0.000
T37.5 Antiviral drugs
0.441 0.559 0.000
T37.4 Anthelminthics
0.441 0.559 0.000
T37.3 Other antiprotozoal drugs
0.441 0.559 0.000
T37.1 Antimycobacterial drugs
0.441 0.559 0.000
T37.0 Sulphonamides
0.441 0.559 0.000
T47.2 Stimulant laxatives
0.438 0.562 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.436 0.564 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.436 0.564 0.000
G36.9 Acute disseminated demyelination, unspecified
0.000 0.565 0.435
G36.8 Other specified acute disseminated demyelination
0.000 0.565 0.435
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.565 0.435
E11.6 With other specified complications
0.000 0.566 0.434
T49.9 Topical agent, unspecified
0.433 0.567 0.000
T49.8 Other topical agents
0.433 0.567 0.000
T49.7 Dental drugs, topically applied
0.433 0.567 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.433 0.567 0.000
T49.5 Ophthalmological drugs and preparations
0.433 0.567 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.433 0.567 0.000
T49.3 Emollients, demulcents and protectants
0.433 0.567 0.000
T49.2 Local astringents and local detergents
0.433 0.567 0.000
T49.1 Antipruritics
0.433 0.567 0.000
L40 Psoriasis
0.431 0.568 0.001
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.431 0.569 0.000
T41.5 Therapeutic gases
0.431 0.569 0.000
T41.4 Anaesthetic, unspecified
0.431 0.569 0.000
T41.3 Local anaesthetics
0.431 0.569 0.000
T41.2 Other and unspecified general anaesthetics
0.431 0.569 0.000
T41.1 Intravenous anaesthetics
0.431 0.569 0.000
T41.0 Inhaled anaesthetics
0.431 0.569 0.000
G36.0 Neuromyelitis optica [Devic]
0.000 0.569 0.431
E07 Other disorders of thyroid
0.000 0.572 0.428
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.424 0.576 0.000
T42.1 Iminostilbenes
0.423 0.577 0.000
E11.1 With ketoacidosis
0.000 0.577 0.422
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.422 0.578 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.580 0.420
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.418 0.582 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.418 0.582 0.000
T47.7 Emetics
0.418 0.582 0.000
T47.5 Digestants
0.418 0.582 0.000
T47.3 Saline and osmotic laxatives
0.418 0.582 0.000
E11.7 With multiple complications
0.000 0.589 0.411
T37.8 Other specified systemic anti-infectives and antiparasitics
0.410 0.590 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.410 0.590 0.000
T42.2 Succinimides and oxazolidinediones
0.410 0.590 0.000
T47.4 Other laxatives
0.403 0.597 0.000
T47.0 Histamine H(2)-receptor antagonists
0.403 0.597 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.600 0.400
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.399 0.601 0.000
T48.4 Expectorants
0.399 0.601 0.000
T48.3 Antitussives
0.399 0.601 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.399 0.601 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.399 0.601 0.000
T48.0 Oxytocic drugs
0.399 0.601 0.000
E11.8 With unspecified complications
0.000 0.601 0.399
E56.1 Deficiency of vitamin K
0.000 0.606 0.393
T36.9 Systemic antibiotic, unspecified
0.391 0.608 0.000
T36.8 Other systemic antibiotics
0.391 0.608 0.000
T36.7 Antifungal antibiotics, systemically used
0.391 0.608 0.000
T36.6 Rifamycins
0.391 0.608 0.000
T36.5 Aminoglycosides
0.391 0.608 0.000
T36.3 Macrolides
0.391 0.608 0.000
T36.2 Chloramphenicol group
0.391 0.608 0.000
T48.5 Anti-common-cold drugs
0.385 0.615 0.000
T47.6 Antidiarrhoeal drugs
0.385 0.615 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.620 0.380
E44.0 Moderate protein-energy malnutrition
0.000 0.620 0.380
E20 Hypoparathyroidism
0.000 0.626 0.374
T48.6 Antiasthmatics, not elsewhere classified
0.371 0.629 0.000
T36.4 Tetracyclines
0.363 0.637 0.000
L40.8 Other psoriasis
0.361 0.638 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.357 0.643 0.000
T42.4 Benzodiazepines
0.356 0.644 0.000
E31 Polyglandular dysfunction
0.000 0.647 0.353
E27.2 Addisonian crisis
0.000 0.652 0.348
E24 Cushing's syndrome
0.000 0.653 0.347
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.345 0.654 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.655 0.345
E27.0 Other adrenocortical overactivity
0.000 0.655 0.345
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.656 0.344
E32 Diseases of thymus
0.000 0.656 0.344
E30 Disorders of puberty, not elsewhere classified
0.000 0.656 0.344
L40.0 Psoriasis vulgaris
0.344 0.656 0.000
E25 Adrenogenital disorders
0.000 0.669 0.331
E27.9 Disorder of adrenal gland, unspecified
0.000 0.676 0.324
T36.0 Penicillins
0.323 0.677 0.000
L40.4 Guttate psoriasis
0.313 0.687 0.001
E61.1 Iron deficiency
0.000 0.687 0.313
L40.2 Acrodermatitis continua
0.309 0.690 0.001
E07.1 Dyshormogenetic goitre
0.000 0.693 0.307
E07.0 Hypersecretion of calcitonin
0.000 0.693 0.307
E67 Other hyperalimentation
0.000 0.699 0.301
E68 Sequelae of hyperalimentation
0.000 0.699 0.301
E20.9 Hypoparathyroidism, unspecified
0.000 0.702 0.298
E34 Other endocrine disorders
0.000 0.705 0.294
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.710 0.290
E24.0 Pituitary-dependent Cushing's disease
0.000 0.715 0.285
L40.5 Arthropathic psoriasis
0.277 0.723 0.000
E11.2 With renal complications
0.000 0.726 0.274
E20.8 Other hypoparathyroidism
0.000 0.732 0.268
E20.1 Pseudohypoparathyroidism
0.000 0.732 0.268
E20.0 Idiopathic hypoparathyroidism
0.000 0.732 0.268
L40.1 Generalised pustular psoriasis
0.262 0.737 0.001
E31.0 Autoimmune polyglandular failure
0.000 0.738 0.262
M35.0 Sicca syndrome [Sjogren]
0.000 0.738 0.262
L40.3 Pustulosis palmaris et plantaris
0.260 0.739 0.001
E07.8 Other specified disorders of thyroid
0.000 0.744 0.256
E31.9 Polyglandular dysfunction, unspecified
0.000 0.747 0.253
E31.8 Other polyglandular dysfunction
0.000 0.747 0.253
E31.1 Polyglandular hyperfunction
0.000 0.747 0.253
E11.3 With ophthalmic complications
0.000 0.747 0.253
E24.9 Cushing's syndrome, unspecified
0.000 0.748 0.252
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.751 0.249
E24.3 Ectopic ACTH syndrome
0.000 0.751 0.249
E24.1 Nelson's syndrome
0.000 0.751 0.249
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.247 0.753 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.753 0.247
E30.8 Other disorders of puberty
0.000 0.753 0.247
E30.1 Precocious puberty
0.000 0.753 0.247
E30.0 Delayed puberty
0.000 0.753 0.247
E32.9 Disease of thymus, unspecified
0.000 0.753 0.247
E32.8 Other diseases of thymus
0.000 0.753 0.247
E32.1 Abscess of thymus
0.000 0.753 0.247
E32.0 Persistent hyperplasia of thymus
0.000 0.753 0.247
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.753 0.247
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.753 0.247
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.753 0.247
E24.8 Other Cushing's syndrome
0.000 0.759 0.241
E25.9 Adrenogenital disorder, unspecified
0.000 0.762 0.237
E25.8 Other adrenogenital disorders
0.000 0.762 0.237
E03 Other hypothyroidism
0.000 0.763 0.236
E66 Obesity
0.000 0.764 0.236
E34.8 Other specified endocrine disorders
0.000 0.767 0.232
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.776 0.224
D25 Leiomyoma of uterus
0.219 0.781 0.000
E66.8 Other obesity
0.000 0.782 0.218
E67.8 Other specified hyperalimentation
0.000 0.784 0.216
E67.3 Hypervitaminosis D
0.000 0.784 0.216
E67.2 Megavitamin-B6 syndrome
0.000 0.784 0.216
E67.1 Hypercarotenaemia
0.000 0.784 0.216
E67.0 Hypervitaminosis A
0.000 0.784 0.216
E27.3 Drug-induced adrenocortical insufficiency
0.001 0.785 0.215
E29 Testicular dysfunction
0.001 0.788 0.211
E34.5 Androgen resistance syndrome
0.000 0.789 0.211
E34.4 Constitutional tall stature
0.000 0.789 0.211
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.789 0.211
E34.1 Other hypersecretion of intestinal hormones
0.000 0.789 0.211
E27.8 Other specified disorders of adrenal gland
0.000 0.795 0.204
E24.2 Drug-induced Cushing's syndrome
0.000 0.796 0.204
E28 Ovarian dysfunction
0.000 0.797 0.203
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.797 0.203
E26 Hyperaldosteronism
0.001 0.798 0.201
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.799 0.201
C85.1 B-cell lymphoma, unspecified
0.000 0.800 0.200
E04 Other non-toxic goitre
0.000 0.800 0.200
E34.9 Endocrine disorder, unspecified
0.000 0.801 0.199
D18.0 Haemangioma, any site
0.196 0.804 0.000
E34.0 Carcinoid syndrome
0.000 0.807 0.193
T40.5 Cocaine
0.192 0.807 0.000
E22 Hyperfunction of pituitary gland
0.000 0.808 0.192
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.812 0.188
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.177 0.822 0.000
T40.8 Lysergide [LSD]
0.177 0.822 0.000
T40.7 Cannabis (derivatives)
0.177 0.822 0.000
T40.3 Methadone
0.177 0.822 0.000
T40.0 Opium
0.177 0.822 0.000
D25.2 Subserosal leiomyoma of uterus
0.175 0.825 0.000
D25.0 Submucous leiomyoma of uterus
0.172 0.828 0.000
T40.1 Heroin
0.171 0.828 0.000
E03.5 Myxoedema coma
0.000 0.830 0.170
E03.4 Atrophy of thyroid (acquired)
0.000 0.830 0.170
E03.3 Postinfectious hypothyroidism
0.000 0.830 0.170
E66.1 Drug-induced obesity
0.000 0.830 0.169
E34.3 Short stature, not elsewhere classified
0.001 0.832 0.167
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.838 0.162
E03.1 Congenital hypothyroidism without goitre
0.000 0.838 0.161
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.841 0.159
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.842 0.158
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.843 0.157
E29.8 Other testicular dysfunction
0.001 0.848 0.151
E29.0 Testicular hyperfunction
0.001 0.848 0.151
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.849 0.151
E04.0 Non-toxic diffuse goitre
0.000 0.849 0.151
E65 Localised adiposity
0.001 0.849 0.150
E14.9 Without complications
0.000 0.851 0.149
N04.9 Unspecified
0.000 0.851 0.149
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.852 0.148
E03.8 Other specified hypothyroidism
0.000 0.853 0.147
E28.9 Ovarian dysfunction, unspecified
0.000 0.854 0.145
E28.8 Other ovarian dysfunction
0.000 0.854 0.145
E28.1 Androgen excess
0.000 0.854 0.145
E28.0 Oestrogen excess
0.000 0.854 0.145
C85.0 Lymphosarcoma
0.000 0.854 0.146
E26.8 Other hyperaldosteronism
0.001 0.855 0.144
E26.1 Secondary hyperaldosteronism
0.001 0.855 0.144
E04.8 Other specified non-toxic goitre
0.000 0.857 0.143
I10-I15 Hypertensive diseases
0.143 0.857 0.001
B37.8 Candidiasis of other sites
0.000 0.857 0.143
N04 Nephrotic syndrome
0.000 0.857 0.143
R04 Haemorrhage from respiratory passages
0.142 0.858 0.000
E29.9 Testicular dysfunction, unspecified
0.001 0.858 0.141
E07.9 Disorder of thyroid, unspecified
0.000 0.859 0.141
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.862 0.138
E22.8 Other hyperfunction of pituitary gland
0.000 0.862 0.138
T40.6 Other and unspecified narcotics
0.137 0.863 0.000
E23 Hypofunction and other disorders of pituitary gland
0.001 0.864 0.135
L40-L45 Papulosquamous disorders
0.121 0.867 0.012
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.867 0.133
F41.9 Anxiety disorder, unspecified
0.131 0.869 0.000
N00-N08 Glomerular diseases
0.000 0.869 0.131
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.872 0.128
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.874 0.126
E28.3 Primary ovarian failure
0.000 0.876 0.124
E22.1 Hyperprolactinaemia
0.000 0.876 0.124
E22.0 Acromegaly and pituitary gigantism
0.000 0.876 0.124
N04.1 Focal and segmental glomerular lesions
0.000 0.881 0.119
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.883 0.117
E21.2 Other hyperparathyroidism
0.000 0.883 0.117
N04.2 Diffuse membranous glomerulonephritis
0.000 0.884 0.116
E66.0 Obesity due to excess calories
0.000 0.884 0.116
E26.9 Hyperaldosteronism, unspecified
0.001 0.885 0.113
N05 Unspecified nephritic syndrome
0.000 0.885 0.115
R04.8 Haemorrhage from other sites in respiratory passages
0.114 0.886 0.000
R04.1 Haemorrhage from throat
0.110 0.890 0.000
F41 Other anxiety disorders
0.110 0.890 0.000
I13 Hypertensive heart and renal disease
0.109 0.891 0.001
F41.2 Mixed anxiety and depressive disorder
0.108 0.892 0.000
T40.2 Other opioids
0.108 0.892 0.000
N05.2 Diffuse membranous glomerulonephritis
0.000 0.892 0.108
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.894 0.106
C88 Malignant immunoproliferative diseases
0.000 0.895 0.105
N04.8 Other
0.000 0.898 0.102
N04.7 Diffuse crescentic glomerulonephritis
0.000 0.898 0.102
N04.6 Dense deposit disease
0.000 0.898 0.102
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.898 0.102

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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