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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2747460
log Bayes Factor = 90.9925
Chromosome 6   position 29,657,127  (GRCh37) Explore rs2747460 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.998 0.002 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
K51 Ulcerative colitis
0.000 0.005 0.995
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.994 0.006 0.000
# Top node
0.994 0.006 0.000
E10.1 With ketoacidosis
0.993 0.007 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.008 0.992
E16 Other disorders of pancreatic internal secretion
0.990 0.010 0.000
M17 Gonarthrosis [arthrosis of knee]
0.989 0.011 0.000
M17.9 Gonarthrosis, unspecified
0.988 0.012 0.000
M15-M19 Arthrosis
0.988 0.012 0.000
E16.2 Hypoglycaemia, unspecified
0.988 0.012 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.014 0.986
M05-M14 Inflammatory polyarthropathies
0.986 0.014 0.000
M07 Psoriatic and enteropathic arthropathies
0.985 0.015 0.000
M07.3 Other psoriatic arthropathies
0.984 0.016 0.000
L40-L45 Papulosquamous disorders
0.980 0.020 0.000
E10.3 With ophthalmic complications
0.979 0.021 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.973 0.027 0.000
K51.4 Pseudopolyposis of colon
0.000 0.031 0.969
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.965 0.035 0.000
M17.1 Other primary gonarthrosis
0.963 0.037 0.000
N00-N08 Glomerular diseases
0.960 0.040 0.000
Chapter XIV Diseases of the genitourinary system
0.957 0.043 0.000
N13 Obstructive and reflux uropathy
0.957 0.043 0.000
N10-N16 Renal tubulo-interstitial diseases
0.956 0.044 0.000
M86-M90 Other osteopathies
0.949 0.051 0.000
M20-M25 Other joint disorders
0.949 0.051 0.000
E14 Unspecified diabetes mellitus
0.944 0.056 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.943 0.057 0.000
E10.2 With renal complications
0.942 0.058 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.941 0.059 0.000
K50-K52 Noninfective enteritis and colitis
0.046 0.063 0.891
N04 Nephrotic syndrome
0.936 0.064 0.000
M35 Other systemic involvement of connective tissue
0.931 0.069 0.000
Chapter VI Diseases of the nervous system
0.929 0.071 0.000
E10.4 With neurological complications
0.929 0.071 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.928 0.072 0.000
M35.0 Sicca syndrome [Sjogren]
0.927 0.073 0.000
M25 Other joint disorders, not elsewhere classified
0.927 0.073 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.927 0.073 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.925 0.075 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.924 0.076 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.924 0.076 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.920 0.080 0.000
M60-M63 Disorders of muscles
0.919 0.081 0.000
G35 Multiple sclerosis
0.914 0.086 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.911 0.089 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.910 0.090 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.906 0.094 0.000
G30-G32 Other degenerative diseases of the nervous system
0.902 0.098 0.000
N04.9 Unspecified
0.900 0.100 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.898 0.102 0.000
E07 Other disorders of thyroid
0.897 0.103 0.000
N05 Unspecified nephritic syndrome
0.890 0.110 0.000
K50 Crohn's disease [regional enteritis]
0.003 0.110 0.887
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.889 0.111 0.000
K50.9 Crohn's disease, unspecified
0.000 0.116 0.884
M25.5 Pain in joint
0.882 0.118 0.000
L40.0 Psoriasis vulgaris
0.882 0.118 0.000
K51.8 Other ulcerative colitis
0.000 0.123 0.877
M89 Other disorders of bone
0.874 0.126 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.867 0.133 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.134 0.866
N11 Chronic tubulo-interstitial nephritis
0.865 0.135 0.000
M62 Other disorders of muscle
0.861 0.139 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.856 0.144 0.000
G37 Other demyelinating diseases of central nervous system
0.855 0.145 0.000
E14.3 With ophthalmic complications
0.855 0.145 0.000
D80-D89 Certain disorders involving the immune mechanism
0.852 0.148 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.849 0.151 0.000
M86 Osteomyelitis
0.848 0.152 0.000
M25.56 Pain in joint (Lower leg)
0.847 0.153 0.000
M35.7 Hypermobility syndrome
0.843 0.157 0.000
E14.5 With peripheral circulatory complications
0.838 0.162 0.000
M91-M94 Chondropathies
0.837 0.163 0.000
G70-G73 Diseases of myoneural junction and muscle
0.836 0.164 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.835 0.165 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.167 0.833
D55-D59 Haemolytic anaemias
0.829 0.171 0.000
G31.8 Other specified degenerative diseases of nervous system
0.826 0.174 0.000
E07.8 Other specified disorders of thyroid
0.826 0.174 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.823 0.177 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.823 0.177 0.000
N13.6 Pyonephrosis
0.822 0.178 0.000
M10 Gout
0.819 0.181 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.818 0.182 0.000
Q76 Congenital malformations of spine and bony thorax
0.816 0.184 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.807 0.193 0.000
M62.8 Other specified disorders of muscle
0.804 0.196 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.804 0.196 0.000
L40.1 Generalised pustular psoriasis
0.803 0.197 0.000
M31 Other necrotising vasculopathies
0.794 0.206 0.000
E10.0 With coma
0.794 0.206 0.000
M17.5 Other secondary gonarthrosis
0.792 0.208 0.000
D86 Sarcoidosis
0.791 0.209 0.000
M25.54 Pain in joint (Hand)
0.791 0.209 0.000
N05.2 Diffuse membranous glomerulonephritis
0.788 0.212 0.000
N04.2 Diffuse membranous glomerulonephritis
0.788 0.212 0.000
K90 Intestinal malabsorption
0.788 0.212 0.000
K50.1 Crohn's disease of large intestine
0.000 0.213 0.787
G31.0 Circumscribed brain atrophy
0.787 0.213 0.000
D50-D53 Nutritional anaemias
0.786 0.214 0.000
M11 Other crystal arthropathies
0.783 0.217 0.000
M25.57 Pain in joint (Ankle and foot)
0.782 0.218 0.000
M00-M03 Infectious arthropathies
0.781 0.219 0.000
E05.8 Other thyrotoxicosis
0.781 0.219 0.000
Q00-Q07 Congenital malformations of the nervous system
0.774 0.226 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.773 0.226 0.000
G70 Myasthenia gravis and other myoneural disorders
0.772 0.228 0.000
N25-N29 Other disorders of kidney and ureter
0.772 0.228 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.771 0.229 0.000
M25.4 Effusion of joint
0.771 0.229 0.000
M25.9 Joint disorder, unspecified
0.767 0.233 0.000
E11 Non-insulin-dependent diabetes mellitus
0.766 0.234 0.000
M21 Other acquired deformities of limbs
0.765 0.235 0.000
M32 Systemic lupus erythematosus
0.763 0.237 0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.757 0.243 0.000
M93 Other osteochondropathies
0.756 0.244 0.000
N02 Recurrent and persistent haematuria
0.755 0.244 0.000
M07.38 Other psoriatic arthropathies (Other)
0.752 0.248 0.000
E13 Other specified diabetes mellitus
0.751 0.249 0.000
E40-E46 Malnutrition
0.750 0.250 0.000
E20-E35 Disorders of other endocrine glands
0.749 0.251 0.000
Q40 Other congenital malformations of upper alimentary tract
0.749 0.251 0.000
M10.0 Idiopathic gout
0.746 0.254 0.000
Q65 Congenital deformities of hip
0.745 0.255 0.000
E10.7 With multiple complications
0.744 0.256 0.000
M89.5 Osteolysis
0.739 0.261 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.739 0.261 0.000
E14.2 Withrenal complications
0.739 0.261 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.735 0.265 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.734 0.266 0.000
M88 Paget's disease of bone [osteitis deformans]
0.733 0.267 0.000
E10.6 With other specified complications
0.733 0.267 0.000
M12 Other specific arthropathies
0.732 0.268 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.732 0.268 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.731 0.269 0.000
M65-M68 Disorders of synovium and tendon
0.730 0.270 0.000
L40.4 Guttate psoriasis
0.730 0.270 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.728 0.272 0.000
M14 Arthropathies in other diseases classified elsewhere
0.728 0.272 0.000
L40.3 Pustulosis palmaris et plantaris
0.727 0.273 0.000
E10.8 With unspecified complications
0.727 0.273 0.000
G70.0 Myasthenia gravis
0.726 0.274 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.726 0.274 0.000
D50 Iron deficiency anaemia
0.726 0.274 0.000
D86.9 Sarcoidosis, unspecified
0.726 0.274 0.000
M89.0 Algoneurodystrophy
0.722 0.278 0.000
M21.0 Valgus deformity, not elsewhere classified
0.721 0.279 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.720 0.280 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.720 0.280 0.000
L42 Pityriasis rosea
0.720 0.280 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.719 0.281 0.000
M07.6 Other enteropathic arthropathies
0.718 0.281 0.000
M31.6 Other giant cell arteritis
0.718 0.282 0.000
N05.1 Focal and segmental glomerular lesions
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E50-E64 Other nutritional deficiencies
0.716 0.284 0.000
D58 Other hereditary haemolytic anaemias
0.714 0.286 0.000
E15 Nondiabetic hypoglycaemic coma
0.713 0.287 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.712 0.287 0.000
N11.1 Chronic obstructive pyelonephritis
0.712 0.288 0.000
L50-L54 Urticaria and erythema
0.711 0.289 0.000
L10-L14 Bullous disorders
0.710 0.289 0.000
M86.6 Other chronic osteomyelitis
0.710 0.290 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.710 0.290 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.710 0.290 0.000
E16.4 Abnormal secretion of gastrin
0.710 0.290 0.000
E16.3 Increased secretion of glucagon
0.710 0.290 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.709 0.291 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.292 0.708
M25.3 Other instability of joint
0.708 0.292 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.707 0.293 0.000
M08 Juvenile arthritis
0.707 0.293 0.000
M89.3 Hypertrophy of bone
0.707 0.293 0.000
E14.8 With unspecified complications
0.707 0.293 0.000
N25 Disorders resulting from impaired renal tubular function
0.706 0.294 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.706 0.294 0.000
M07.5 Arthropathy in ulcerative colitis
0.706 0.294 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.706 0.294 0.000
M07.2 Psoriatic spondylitis
0.706 0.294 0.000
M07.1 Arthritis mutilans
0.706 0.294 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.706 0.294 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.706 0.294 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.706 0.294 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.706 0.294 0.000
Chapter I Certain infectious and parasitic diseases
0.704 0.296 0.000
L44 Other papulosquamous disorders
0.703 0.297 0.000
L41 Parapsoriasis
0.703 0.297 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.703 0.297 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.699 0.300 0.000
E16.1 Other hypoglycaemia
0.699 0.301 0.000
M89.9 Disorder of bone, unspecified
0.699 0.301 0.000
D50.9 Iron deficiency anaemia, unspecified
0.696 0.304 0.000
Q78 Other osteochondrodysplasias
0.696 0.304 0.000
M86.9 Osteomyelitis, unspecified
0.695 0.305 0.000
N04.1 Focal and segmental glomerular lesions
0.694 0.306 0.000
E14.1 With ketoacidosis
0.694 0.306 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.692 0.308 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.691 0.309 0.000
K51.5 Mucosal proctocolitis
0.000 0.310 0.690
B35-B49 Mycoses
0.689 0.311 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.688 0.312 0.000
N06 Isolated proteinuria with specified morphological lesion
0.688 0.312 0.000
N01 Rapidly progressive nephritic syndrome
0.688 0.312 0.000
N00 Acute nephritic syndrome
0.688 0.312 0.000
E11.2 With renal complications
0.688 0.312 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.312 0.688
Q60-Q64 Congenital malformations of the urinary system
0.686 0.313 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.685 0.315 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.685 0.315 0.000
E11.6 With other specified complications
0.685 0.315 0.000
N04.0 Minor glomerular abnormality
0.684 0.316 0.000
N15 Other renal tubulo-interstitial diseases
0.683 0.317 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.683 0.317 0.000
M25.58 Pain in joint (Other)
0.682 0.318 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.681 0.319 0.000
E14.7 With multiple complications
0.677 0.323 0.000
E14.0 With coma
0.677 0.323 0.000
Q70 Syndactyly
0.677 0.323 0.000
B37 Candidiasis
0.677 0.323 0.000
Q76.0 Spina bifida occulta
0.677 0.323 0.000
N05.8 Other
0.676 0.324 0.000
E06 Thyroiditis
0.675 0.325 0.000
M33 Dermatopolymyositis
0.675 0.325 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.675 0.325 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.675 0.325 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.675 0.325 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.675 0.325 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.675 0.325 0.000
Q35-Q37 Cleft lip and cleft palate
0.675 0.325 0.000
N04.8 Other
0.671 0.329 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.671 0.329 0.000
N04.6 Dense deposit disease
0.671 0.329 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.671 0.329 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.671 0.329 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.671 0.329 0.000
M25.59 Pain in joint (Site unspecified)
0.669 0.331 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.669 0.331 0.000
Q74 Other congenital malformations of limb(s)
0.668 0.331 0.000
M60 Myositis
0.668 0.332 0.000
E14.6 With other specified complications
0.668 0.332 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.668 0.332 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.668 0.332 0.000
M35.5 Multifocal fibrosclerosis
0.668 0.332 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.668 0.332 0.000
M25.2 Flail joint
0.664 0.335 0.000
M25.1 Fistula of joint
0.664 0.335 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.664 0.336 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.664 0.336 0.000
G36 Other acute disseminated demyelination
0.663 0.337 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.662 0.338 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.660 0.340 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.659 0.341 0.000
M61 Calcification and ossification of muscle
0.659 0.341 0.000
D83 Common variable immunodeficiency
0.658 0.342 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.658 0.342 0.000
Q40.2 Other specified congenital malformations of stomach
0.657 0.343 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.656 0.344 0.000
D60-D64 Aplastic and other anaemias
0.656 0.344 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.656 0.344 0.000
M25.46 Effusion of joint (Lower leg)
0.655 0.345 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.655 0.345 0.000
M25.47 Effusion of joint (Ankle and foot)
0.654 0.346 0.000
L40.8 Other psoriasis
0.653 0.347 0.000
E11.1 With ketoacidosis
0.652 0.348 0.000
D66 Hereditary factor VIII deficiency
0.652 0.348 0.000
M86.8 Other osteomyelitis
0.650 0.350 0.000
M93.9 Osteochondropathy, unspecified
0.650 0.350 0.000
M11.2 Other chondrocalcinosis
0.648 0.352 0.000
N26 Unspecified contracted kidney
0.648 0.352 0.000
M18 Arthrosis of first carpometacarpal joint
0.647 0.353 0.000
M00 Pyogenic arthritis
0.646 0.354 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.646 0.354 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.644 0.356 0.000
Q75 Other congenital malformations of skull and face bones
0.644 0.356 0.000
Q73 Reduction defects of unspecified limb
0.644 0.356 0.000
Q72 Reduction defects of lower limb
0.644 0.356 0.000
Q71 Reduction defects of upper limb
0.644 0.356 0.000
Q69 Polydactyly
0.644 0.356 0.000
Q68 Other congenital musculoskeletal deformities
0.644 0.356 0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances
0.643 0.357 0.000
E07.1 Dyshormogenetic goitre
0.643 0.357 0.000
E07.0 Hypersecretion of calcitonin
0.643 0.357 0.000
M89.55 Osteolysis (Pelvic region and thigh)
0.643 0.357 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.642 0.358 0.000
M93.1 Kienbock's disease of adults
0.641 0.359 0.000
N02.2 Diffuse membranous glomerulonephritis
0.640 0.359 0.000
D86.0 Sarcoidosis of lung
0.639 0.361 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.638 0.362 0.000
N05.6 Dense deposit disease
0.638 0.362 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.638 0.362 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.638 0.362 0.000
N05.0 Minor glomerular abnormality
0.638 0.362 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.638 0.362 0.000
N02.9 Unspecified
0.636 0.364 0.000
M15 Polyarthrosis
0.636 0.364 0.000
K90.9 Intestinal malabsorption, unspecified
0.636 0.364 0.000
M62.0 Diastasis of muscle
0.635 0.365 0.000
B02 Zoster [herpes zoster]
0.635 0.365 0.000
Q65.8 Other congenital deformities of hip
0.635 0.365 0.000
D73 Diseases of spleen
0.635 0.365 0.000
M62.88 Other specified disorders of muscle (Other)
0.635 0.365 0.000
B37.8 Candidiasis of other sites
0.634 0.366 0.000
M25.7 Osteophyte
0.632 0.368 0.000
E07.9 Disorder of thyroid, unspecified
0.632 0.368 0.000
M21.8 Other specified acquired deformities of limbs
0.630 0.370 0.000
Q45 Other congenital malformations of digestive system
0.630 0.370 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.629 0.371 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.629 0.371 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.628 0.372 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.627 0.373 0.000
M89.6 Osteopathy after poliomyelitis
0.627 0.373 0.000
M89.2 Other disorders of bone development and growth
0.627 0.373 0.000
M89.1 Epiphyseal arrest
0.627 0.373 0.000
Q66 Congenital deformities of feet
0.627 0.373 0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis
0.627 0.373 0.000
Q40.1 Congenital hiatus hernia
0.626 0.374 0.000
E24 Cushing's syndrome
0.626 0.374 0.000
D59 Acquired haemolytic anaemia
0.625 0.375 0.000
M62.6 Muscle strain
0.624 0.376 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.623 0.377 0.000
E20 Hypoparathyroidism
0.622 0.378 0.000
M25.42 Effusion of joint (Upper arm)
0.622 0.378 0.000
M25.53 Pain in joint (Forearm)
0.622 0.378 0.000
M90 Osteopathies in diseases classified elsewhere
0.621 0.379 0.000
M25.76 Osteophyte (Lower leg)
0.620 0.380 0.000
N11.8 Other chronic tubulo-interstitial nephritis
0.620 0.380 0.000
B37.9 Candidiasis, unspecified
0.619 0.381 0.000
Q03 Congenital hydrocephalus
0.619 0.381 0.000
N25.8 Other disorders resulting from impaired renal tubular function
0.619 0.381 0.000
M87 Osteonecrosis
0.618 0.382 0.000
E11.5 With peripheral circulatory complications
0.618 0.382 0.000
E27 Other disorders of adrenal gland
0.618 0.382 0.000
E11.7 With multiple complications
0.618 0.382 0.000
M62.9 Disorder of muscle, unspecified
0.617 0.383 0.000
M62.4 Contracture of muscle
0.617 0.383 0.000
M62.3 Immobility syndrome (paraplegic)
0.617 0.383 0.000
M62.2 Ischaemic infarction of muscle
0.617 0.383 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.617 0.383 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.617 0.383 0.000
M25.0 Haemarthrosis
0.617 0.383 0.000
M10.00 Idiopathic gout (Multiple sites)
0.615 0.385 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.614 0.386 0.000
D58.0 Hereditary spherocytosis
0.614 0.386 0.000
G37.5 Concentric sclerosis [Balo]
0.613 0.387 0.000
G37.4 Subacute necrotising myelitis
0.613 0.387 0.000
G37.2 Central pontine myelinolysis
0.613 0.387 0.000
G37.1 Central demyelination of corpus callosum
0.613 0.387 0.000
G37.0 Diffuse sclerosis
0.613 0.387 0.000
M25.36 Other instability of joint (Lower leg)
0.612 0.388 0.000
D86.8 Sarcoidosis of other and combined sites
0.612 0.388 0.000
M25.52 Pain in joint (Upper arm)
0.612 0.388 0.000
D81 Combined immunodeficiencies
0.611 0.389 0.000
G72 Other myopathies
0.611 0.389 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.611 0.389 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.610 0.390 0.000
I83 Varicose veins of lower extremities
0.000 0.391 0.609
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.608 0.391 0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.608 0.391 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.608 0.392 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.608 0.392 0.000
M86.3 Chronic multifocal osteomyelitis
0.608 0.392 0.000
M86.2 Subacute osteomyelitis
0.608 0.392 0.000
M86.1 Other acute osteomyelitis
0.608 0.392 0.000
M86.0 Acute haematogenous osteomyelitis
0.608 0.392 0.000
M67 Other disorders of synovium and tendon
0.607 0.393 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.606 0.394 0.000
K50.8 Other Crohn's disease
0.002 0.394 0.605
M10.02 Idiopathic gout (Upper arm)
0.606 0.394 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.604 0.396 0.000
E14.4 With neurological complications
0.603 0.396 0.000
D68 Other coagulation defects
0.603 0.397 0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.602 0.398 0.000
E27.1 Primary adrenocortical insufficiency
0.602 0.398 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.601 0.399 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.601 0.399 0.000
D56 Thalassaemia
0.601 0.399 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.599 0.401 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.599 0.401 0.000
E25 Adrenogenital disorders
0.599 0.401 0.000
M31.0 Hypersensitivity angiitis
0.597 0.403 0.000
B02.9 Zoster without complication
0.597 0.403 0.000
K90.8 Other intestinal malabsorption
0.595 0.405 0.000
E23 Hypofunction and other disorders of pituitary gland
0.595 0.405 0.000
D57 Sickle-cell disorders
0.594 0.406 0.000
D55 Anaemia due to enzyme disorders
0.594 0.406 0.000
D84 Other immunodeficiencies
0.594 0.406 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.593 0.407 0.000
D72 Other disorders of white blood cells
0.593 0.407 0.000
Q79.6 Ehlers-Danlos syndrome
0.593 0.407 0.000
E13.3 With ophthalmic complications
0.591 0.409 0.000
B00 Herpesviral [herpes simplex] infections
0.591 0.409 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.590 0.410 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.590 0.410 0.000
M14.2 Diabetic arthropathy
0.589 0.411 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.589 0.411 0.000
M25.51 Pain in joint (Shoulder region)
0.588 0.412 0.000
M10.4 Other secondary gout
0.587 0.413 0.000
M10.3 Gout due to impairment of renal function
0.587 0.413 0.000
M10.2 Drug-induced gout
0.587 0.413 0.000
M10.1 Lead-induced gout
0.587 0.413 0.000
Q64 Other congenital malformations of urinary system
0.587 0.413 0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified
0.586 0.414 0.000
Q05 Spina bifida
0.586 0.414 0.000
D82 Immunodeficiency associated with other major defects
0.585 0.415 0.000
M89.06 Algoneurodystrophy (Lower leg)
0.585 0.415 0.000
Q76.9 Congenital malformation of bony thorax, unspecified
0.585 0.415 0.000
Q76.8 Other congenital malformations of bony thorax
0.585 0.415 0.000
Q76.7 Congenital malformation of sternum
0.585 0.415 0.000
Q76.6 Other congenital malformations of ribs
0.585 0.415 0.000
Q76.5 Cervical rib
0.585 0.415 0.000
Q76.3 Congenital scoliosis due to congenital bony malformation
0.585 0.415 0.000
Q76.2 Congenital spondylolisthesis
0.585 0.415 0.000
M25.33 Other instability of joint (Forearm)
0.584 0.416 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.584 0.416 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.583 0.417 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.583 0.417 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.583 0.417 0.000
E14.9 Without complications
0.583 0.417 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.583 0.417 0.000
Q76.1 Klippel-Feil syndrome
0.582 0.418 0.000
M25.43 Effusion of joint (Forearm)
0.581 0.419 0.000
Q04 Other congenital malformations of brain
0.580 0.419 0.000
A15-A19 Tuberculosis
0.580 0.420 0.000
M88.9 Paget's disease of bone, unspecified
0.579 0.421 0.000
Q07 Other congenital malformations of nervous system
0.579 0.421 0.000
E31 Polyglandular dysfunction
0.578 0.422 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.577 0.422 0.000
G71 Primary disorders of muscles
0.577 0.423 0.000
M31.1 Thrombotic microangiopathy
0.577 0.423 0.000
M62.87 Other specified disorders of muscle (Ankle and foot)
0.577 0.423 0.000
D67 Hereditary factor IX deficiency
0.577 0.423 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.576 0.424 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.576 0.424 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.575 0.425 0.000
G00 Bacterial meningitis, not elsewhere classified
0.573 0.427 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.573 0.427 0.000
M35.1 Other overlap syndromes
0.572 0.427 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.572 0.428 0.000
M31.7 Microscopic polyangiitis
0.572 0.428 0.000
E46 Unspecified protein-energy malnutrition
0.571 0.429 0.000
G31.2 Degeneration of nervous system due to alcohol
0.570 0.429 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.430 0.570
N03 Chronic nephritic syndrome
0.569 0.430 0.000
M31.8 Other specified necrotising vasculopathies
0.569 0.431 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.569 0.431 0.000
M31.2 Lethal midline granuloma
0.569 0.431 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.569 0.431 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.569 0.431 0.000
M94 Other disorders of cartilage
0.569 0.431 0.000
E61 Deficiency of other nutrient elements
0.568 0.432 0.000
Q50-Q56 Congenital malformations of genital organs
0.568 0.432 0.000
L94 Other localised connective tissue disorders
0.568 0.432 0.000
M35.2 Behcet's disease
0.567 0.433 0.000
D86.3 Sarcoidosis of skin
0.567 0.433 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.565 0.434 0.000
M10.09 Idiopathic gout (Site unspecified)
0.565 0.434 0.000
M10.06 Idiopathic gout (Lower leg)
0.565 0.435 0.000
M66 Spontaneous rupture of synovium and tendon
0.565 0.435 0.000
K90.3 Pancreatic steatorrhoea
0.565 0.435 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.565 0.435 0.000
K90.1 Tropical sprue
0.565 0.435 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.565 0.435 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.563 0.436 0.000
E11.0 With coma
0.563 0.437 0.000
E51 Thiamine deficiency
0.563 0.437 0.000
Chapter XX External causes of morbidity and mortality
0.563 0.437 0.000
N05.9 Unspecified
0.563 0.437 0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)
0.563 0.437 0.000
D80 Immunodeficiency with predominantly antibody defects
0.562 0.437 0.000
L93 Lupus erythematosus
0.562 0.438 0.000
M25.93 Joint disorder, unspecified (Forearm)
0.562 0.438 0.000
M11.1 Familial chondrocalcinosis
0.561 0.439 0.000
M11.0 Hydroxyapatite deposition disease
0.561 0.439 0.000
M89.37 Hypertrophy of bone (Ankle and foot)
0.561 0.439 0.000
L53 Other erythematous conditions
0.561 0.439 0.000
M89.09 Algoneurodystrophy (Site unspecified)
0.560 0.440 0.000
M12.2 Villonodular synovitis (pigmented)
0.560 0.440 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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