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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2754767
log Bayes Factor = 52.9131
Chromosome 6   position 28,775,241  (GRCh37) Explore rs2754767 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E10.9 Without complications
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.004 0.996
E10-E14 Diabetes mellitus
0.000 0.005 0.995
E16.2 Hypoglycaemia, unspecified
0.000 0.006 0.994
E16 Other disorders of pancreatic internal secretion
0.000 0.007 0.993
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.007 0.993
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.007 0.993
E10.3 With ophthalmic complications
0.000 0.007 0.993
E00-E07 Disorders of thyroid gland
0.000 0.009 0.991
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.054 0.946
E10.2 With renal complications
0.000 0.076 0.924
E10.1 With ketoacidosis
0.000 0.086 0.914
E10.4 With neurological complications
0.000 0.130 0.870
E05.8 Other thyrotoxicosis
0.000 0.188 0.812
E13 Other specified diabetes mellitus
0.000 0.192 0.808
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.212 0.788
E16.1 Other hypoglycaemia
0.000 0.223 0.777
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.771 0.229 0.000
E10.7 With multiple complications
0.000 0.251 0.749
E10.0 With coma
0.000 0.278 0.722
E05.5 Thyroid crisis or storm
0.000 0.286 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.286 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.286 0.714
E12 Malnutrition-related diabetes mellitus
0.000 0.287 0.713
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.288 0.712
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.288 0.712
E16.4 Abnormal secretion of gastrin
0.000 0.288 0.712
E16.3 Increased secretion of glucagon
0.000 0.288 0.712
E15 Nondiabetic hypoglycaemic coma
0.000 0.288 0.712
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.290 0.710
E00 Congenital iodine-deficiency syndrome
0.000 0.290 0.710
E40-E46 Malnutrition
0.000 0.311 0.689
E14 Unspecified diabetes mellitus
0.000 0.325 0.675
E13.9 Without complications
0.000 0.329 0.670
E10.6 With other specified complications
0.000 0.331 0.669
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.364 0.635
E07 Other disorders of thyroid
0.000 0.391 0.609
E06 Thyroiditis
0.000 0.415 0.585
E13.3 With ophthalmic complications
0.000 0.416 0.583
E13.8 With unspecified complications
0.000 0.421 0.579
E13.7 With multiple complications
0.000 0.421 0.579
E13.6 With other specified complications
0.000 0.421 0.579
E13.5 With peripheral circulatory complications
0.000 0.421 0.579
E13.4 With neurological complications
0.000 0.421 0.579
E13.2 With renal complications
0.000 0.421 0.579
E13.1 With ketoacidosis
0.000 0.421 0.579
E13.0 With coma
0.000 0.421 0.579
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.427 0.572
E14.3 With ophthalmic complications
0.000 0.437 0.563
E10.5 With peripheral circulatory complications
0.000 0.437 0.563
E14.1 With ketoacidosis
0.000 0.455 0.545
E14.6 With other specified complications
0.000 0.487 0.513
E12.9 Without complications
0.000 0.488 0.511
E12.8 With unspecified complications
0.000 0.488 0.511
E12.7 With multiple complications
0.000 0.488 0.511
E12.6 With other specified complications
0.000 0.488 0.511
E12.5 With peripheral circulatory complications
0.000 0.488 0.511
E12.4 With neurological complications
0.000 0.488 0.511
E12.3 With ophthalmic complications
0.000 0.488 0.511
E12.2 With renal complications
0.000 0.488 0.511
E12.1 With ketoacidosis
0.000 0.488 0.511
E12.0 With coma
0.000 0.488 0.511
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.491 0.509
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.491 0.509
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.491 0.509
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.491 0.509
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.491 0.509
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.491 0.509
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.491 0.509
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.491 0.509
E10.8 With unspecified complications
0.000 0.491 0.508
E14.4 With neurological complications
0.000 0.497 0.502
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.506 0.494
E45 Retarded development following protein-energy malnutrition
0.000 0.506 0.494
E43 Unspecified severe protein-energy malnutrition
0.000 0.506 0.494
E42 Marasmic kwashiorkor
0.000 0.506 0.494
E41 Nutritional marasmus
0.000 0.506 0.494
E40 Kwashiorkor
0.000 0.506 0.494
E14.8 With unspecified complications
0.000 0.510 0.490
E14.7 With multiple complications
0.000 0.516 0.484
E07.8 Other specified disorders of thyroid
0.000 0.518 0.482
E06.9 Thyroiditis, unspecified
0.000 0.527 0.473
E46 Unspecified protein-energy malnutrition
0.000 0.528 0.472
E14.2 Withrenal complications
0.000 0.538 0.462
E14.5 With peripheral circulatory complications
0.000 0.543 0.457
E14.0 With coma
0.000 0.547 0.453
E06.1 Subacute thyroiditis
0.000 0.560 0.440
E07.1 Dyshormogenetic goitre
0.000 0.563 0.436
E07.0 Hypersecretion of calcitonin
0.000 0.563 0.436
K90 Intestinal malabsorption
0.000 0.567 0.433
E06.4 Drug-induced thyroiditis
0.000 0.580 0.419
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.580 0.419
E06.0 Acute thyroiditis
0.000 0.580 0.419
E06.5 Other chronic thyroiditis
0.000 0.597 0.402
E11 Non-insulin-dependent diabetes mellitus
0.000 0.603 0.397
E03 Other hypothyroidism
0.000 0.607 0.393
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.614 0.385
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.623 0.377
E11.6 With other specified complications
0.000 0.633 0.367
E44.1 Mild protein-energy malnutrition
0.000 0.645 0.354
E44.0 Moderate protein-energy malnutrition
0.000 0.645 0.354
E11.1 With ketoacidosis
0.000 0.651 0.349
E11.0 With coma
0.000 0.662 0.338
E50-E64 Other nutritional deficiencies
0.000 0.677 0.323
K90.3 Pancreatic steatorrhoea
0.000 0.690 0.310
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.690 0.310
K90.1 Tropical sprue
0.000 0.690 0.310
E65-E68 Obesity and other hyperalimentation
0.000 0.691 0.309
K90.8 Other intestinal malabsorption
0.000 0.703 0.297
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.706 0.294
E11.2 With renal complications
0.000 0.711 0.289
E11.7 With multiple complications
0.000 0.715 0.285
E03.5 Myxoedema coma
0.000 0.718 0.282
E03.4 Atrophy of thyroid (acquired)
0.000 0.718 0.282
E03.3 Postinfectious hypothyroidism
0.000 0.718 0.282
E03.1 Congenital hypothyroidism without goitre
0.000 0.729 0.271
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.729 0.271
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.757 0.243
E03.8 Other specified hypothyroidism
0.000 0.760 0.240
E07.9 Disorder of thyroid, unspecified
0.000 0.764 0.236
E54 Ascorbic acid deficiency
0.000 0.765 0.235
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.768 0.232
E63 Other nutritional deficiencies
0.000 0.768 0.232
E50 Vitamin A deficiency
0.000 0.768 0.232
E60 Dietary zinc deficiency
0.000 0.768 0.232
E59 Dietary selenium deficiency
0.000 0.768 0.232
E52 Niacin deficiency [pellagra]
0.000 0.768 0.232
E51 Thiamine deficiency
0.000 0.770 0.230
E11.8 With unspecified complications
0.000 0.776 0.223
E67 Other hyperalimentation
0.000 0.778 0.222
E68 Sequelae of hyperalimentation
0.000 0.778 0.222
E56 Other vitamin deficiencies
0.000 0.781 0.219
E11.5 With peripheral circulatory complications
0.000 0.788 0.212
E55 Vitamin D deficiency
0.000 0.789 0.211
E58 Dietary calcium deficiency
0.000 0.799 0.201
E20-E35 Disorders of other endocrine glands
0.000 0.804 0.196
K90.9 Intestinal malabsorption, unspecified
0.000 0.809 0.191
E83 Disorders of mineral metabolism
0.159 0.820 0.021
M45.X9 Ankylosing spondylitis (Site unspecified)
0.176 0.824 0.000
E24 Cushing's syndrome
0.000 0.824 0.176
E61 Deficiency of other nutrient elements
0.000 0.826 0.173
C15-C26 Malignant neoplasms of digestive organs
0.000 0.830 0.170
C20 Malignant neoplasm of rectum
0.000 0.831 0.169
E50.9 Vitamin A deficiency, unspecified
0.000 0.834 0.166
E50.8 Other manifestations of vitamin A deficiency
0.000 0.834 0.166
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.834 0.166
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.834 0.166
E50.5 Vitamin A deficiency with night blindness
0.000 0.834 0.166
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.834 0.166
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.834 0.166
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.834 0.166
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.834 0.166
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.834 0.166
E63.9 Nutritional deficiency, unspecified
0.000 0.834 0.166
E63.8 Other specified nutritional deficiencies
0.000 0.834 0.166
E63.1 Imbalance of constituents of food intake
0.000 0.834 0.166
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.834 0.166
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.834 0.166
E64.8 Sequelae of other nutritional deficiencies
0.000 0.834 0.166
E64.3 Sequelae of rickets
0.000 0.834 0.166
E64.2 Sequelae of vitamin C deficiency
0.000 0.834 0.166
E64.1 Sequelae of vitamin A deficiency
0.000 0.834 0.166
E64.0 Sequelae of protein-energy malnutrition
0.000 0.834 0.166
E51.9 Thiamine deficiency, unspecified
0.000 0.835 0.165
E51.8 Other manifestations of thiamine deficiency
0.000 0.835 0.165
E51.1 Beriberi
0.000 0.835 0.165
I83 Varicose veins of lower extremities
0.165 0.835 0.000
C15 Malignant neoplasm of oesophagus
0.000 0.836 0.164
E51.2 Wernicke's encephalopathy
0.000 0.836 0.164
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.838 0.162
E53 Deficiency of other B group vitamins
0.000 0.839 0.161
E67.8 Other specified hyperalimentation
0.000 0.841 0.159
E67.3 Hypervitaminosis D
0.000 0.841 0.159
E67.2 Megavitamin-B6 syndrome
0.000 0.841 0.159
E67.1 Hypercarotenaemia
0.000 0.841 0.159
E67.0 Hypervitaminosis A
0.000 0.841 0.159
E65 Localised adiposity
0.000 0.842 0.157
E56.9 Vitamin deficiency, unspecified
0.000 0.843 0.157
E56.8 Deficiency of other vitamins
0.000 0.843 0.157
E56.0 Deficiency of vitamin E
0.000 0.843 0.157
E21.3 Hyperparathyroidism, unspecified
0.000 0.846 0.154
E55.0 Rickets, active
0.000 0.848 0.151
C25 Malignant neoplasm of pancreas
0.000 0.849 0.151
E28 Ovarian dysfunction
0.000 0.851 0.149
E24.9 Cushing's syndrome, unspecified
0.000 0.853 0.147
E20 Hypoparathyroidism
0.000 0.853 0.147
E14.9 Without complications
0.000 0.854 0.146
E24.0 Pituitary-dependent Cushing's disease
0.000 0.854 0.146
C15.4 Middle third of oesophagus
0.000 0.856 0.144
E56.1 Deficiency of vitamin K
0.000 0.856 0.144
E06.3 Autoimmune thyroiditis
0.001 0.859 0.141
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.859 0.141
E32 Diseases of thymus
0.000 0.859 0.141
E30 Disorders of puberty, not elsewhere classified
0.000 0.859 0.141
E25 Adrenogenital disorders
0.000 0.860 0.140
C15.5 Lower third of oesophagus
0.000 0.860 0.140
E83.3 Disorders of phosphorus metabolism
0.134 0.861 0.005
E31 Polyglandular dysfunction
0.000 0.862 0.138
C15.9 Oesophagus, unspecified
0.000 0.863 0.137
E24.2 Drug-induced Cushing's syndrome
0.000 0.867 0.133
E55.9 Vitamin D deficiency, unspecified
0.000 0.869 0.131
E83.8 Other disorders of mineral metabolism
0.114 0.871 0.015
E83.2 Disorders of zinc metabolism
0.114 0.871 0.015
E83.0 Disorders of copper metabolism
0.114 0.871 0.015
E83.9 Disorder of mineral metabolism, unspecified
0.114 0.872 0.014
E24.8 Other Cushing's syndrome
0.000 0.872 0.128
C25.2 Tail of pancreas
0.000 0.873 0.127
C15.0 Cervical part of oesophagus
0.000 0.873 0.127
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.874 0.126
E24.3 Ectopic ACTH syndrome
0.000 0.874 0.126
E24.1 Nelson's syndrome
0.000 0.874 0.126
C25.3 Pancreatic duct
0.000 0.875 0.125
E61.9 Deficiency of nutrient element, unspecified
0.000 0.875 0.124
E61.8 Deficiency of other specified nutrient elements
0.000 0.875 0.124
E61.7 Deficiency of multiple nutrient elements
0.000 0.875 0.124
E61.6 Vanadium deficiency
0.000 0.875 0.124
E61.5 Molybdenum deficiency
0.000 0.875 0.124
E61.4 Chromium deficiency
0.000 0.875 0.124
E61.3 Manganese deficiency
0.000 0.875 0.124
E61.0 Copper deficiency
0.000 0.875 0.124
C17 Malignant neoplasm of small intestine
0.000 0.876 0.124
C25.1 Body of pancreas
0.000 0.878 0.122
E29 Testicular dysfunction
0.000 0.878 0.122
C25.4 Endocrine pancreas
0.000 0.879 0.121
I83.0 Varicose veins of lower extremities with ulcer
0.120 0.880 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.880 0.120
C15.3 Upper third of oesophagus
0.000 0.881 0.119
C15.1 Thoracic part of oesophagus
0.000 0.881 0.119
E53.9 Vitamin B deficiency, unspecified
0.000 0.881 0.119
C15.8 Overlapping lesion of oesophagus
0.000 0.882 0.118
C15.2 Abdominal part of oesophagus
0.000 0.882 0.118
C17.0 Duodenum
0.000 0.882 0.118
C25.8 Overlapping lesion of pancreas
0.000 0.883 0.117
E21.2 Other hyperparathyroidism
0.000 0.883 0.117
E21.4 Other specified disorders of parathyroid gland
0.000 0.883 0.117
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.884 0.116
E53.1 Pyridoxine deficiency
0.000 0.884 0.116
E53.0 Riboflavin deficiency
0.000 0.884 0.116
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.886 0.114
C25.9 Pancreas, unspecified
0.000 0.887 0.113
E20.9 Hypoparathyroidism, unspecified
0.000 0.888 0.112
C21 Malignant neoplasm of anus and anal canal
0.000 0.889 0.111
E34 Other endocrine disorders
0.000 0.890 0.110
E61.2 Magnesium deficiency
0.000 0.890 0.110
E28.9 Ovarian dysfunction, unspecified
0.000 0.893 0.107
E28.8 Other ovarian dysfunction
0.000 0.893 0.107
E28.1 Androgen excess
0.000 0.893 0.107
E28.0 Oestrogen excess
0.000 0.893 0.107
E20.8 Other hypoparathyroidism
0.000 0.894 0.105
E20.1 Pseudohypoparathyroidism
0.000 0.894 0.105
E20.0 Idiopathic hypoparathyroidism
0.000 0.894 0.105
E70-E90 Metabolic disorders
0.002 0.897 0.102
E03.9 Hypothyroidism, unspecified
0.000 0.898 0.102
C24.0 Extrahepatic bile duct
0.000 0.898 0.102
E28.3 Primary ovarian failure
0.000 0.899 0.101
E30.9 Disorder of puberty, unspecified
0.000 0.899 0.101
E30.8 Other disorders of puberty
0.000 0.899 0.101
E30.1 Precocious puberty
0.000 0.899 0.101
E30.0 Delayed puberty
0.000 0.899 0.101
E32.9 Disease of thymus, unspecified
0.000 0.899 0.101
E32.8 Other diseases of thymus
0.000 0.899 0.101
E32.1 Abscess of thymus
0.000 0.899 0.101
E32.0 Persistent hyperplasia of thymus
0.000 0.899 0.101
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.899 0.101
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.899 0.101
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.899 0.101
E11.3 With ophthalmic complications
0.000 0.899 0.101
E25.9 Adrenogenital disorder, unspecified
0.000 0.899 0.100
E25.8 Other adrenogenital disorders
0.000 0.899 0.100
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.900 0.100
E31.9 Polyglandular dysfunction, unspecified
0.000 0.901 0.099
E31.8 Other polyglandular dysfunction
0.000 0.901 0.099
E31.1 Polyglandular hyperfunction
0.000 0.901 0.099
C25.7 Other parts of pancreas
0.000 0.902 0.098
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.902 0.098
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.097 0.902 0.000
E31.0 Autoimmune polyglandular failure
0.000 0.903 0.097
E78.2 Mixed hyperlipidaemia
0.000 0.904 0.096
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.905 0.095
E26 Hyperaldosteronism
0.000 0.908 0.092
E61.1 Iron deficiency
0.000 0.909 0.091
C17.8 Overlapping lesion of small intestine
0.000 0.911 0.089
C17.3 Meckel's diverticulum
0.000 0.911 0.089
E29.9 Testicular dysfunction, unspecified
0.000 0.911 0.089
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.911 0.089
E29.8 Other testicular dysfunction
0.000 0.913 0.087
E29.0 Testicular hyperfunction
0.000 0.913 0.087
E78.1 Pure hyperglyceridaemia
0.000 0.914 0.086
M45 Ankylosing spondylitis
0.084 0.916 0.000
C24.8 Overlapping lesion of biliary tract
0.000 0.917 0.083
E21.0 Primary hyperparathyroidism
0.000 0.919 0.081
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.919 0.080
E78.5 Hyperlipidaemia, unspecified
0.000 0.920 0.080
E34.3 Short stature, not elsewhere classified
0.000 0.920 0.080
C21.2 Cloacogenic zone
0.000 0.920 0.080
C17.1 Jejunum
0.000 0.920 0.079
E11.4 With neurological complications
0.000 0.921 0.079
E34.5 Androgen resistance syndrome
0.000 0.921 0.079
E34.4 Constitutional tall stature
0.000 0.921 0.079
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.921 0.079
E34.1 Other hypersecretion of intestinal hormones
0.000 0.921 0.079
E78.6 Lipoprotein deficiency
0.000 0.921 0.079
E74 Other disorders of carbohydrate metabolism
0.001 0.921 0.078
C23 Malignant neoplasm of gallbladder
0.000 0.921 0.079
E88 Other metabolic disorders
0.001 0.922 0.077
C24.9 Biliary tract, unspecified
0.000 0.925 0.075
E22 Hyperfunction of pituitary gland
0.000 0.925 0.075
E23 Hypofunction and other disorders of pituitary gland
0.000 0.925 0.075
E78.3 Hyperchylomicronaemia
0.000 0.926 0.074
E77 Disorders of glycoprotein metabolism
0.001 0.926 0.073
E76 Disorders of glycosaminoglycan metabolism
0.001 0.926 0.073
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.926 0.073
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.926 0.073
E85 Amyloidosis
0.001 0.926 0.073
E34.8 Other specified endocrine disorders
0.000 0.926 0.074
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.926 0.074
E73 Lactose intolerance
0.001 0.927 0.072
E84 Cystic fibrosis
0.001 0.927 0.072
E34.9 Endocrine disorder, unspecified
0.000 0.928 0.072
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.929 0.071
E70 Disorders of aromatic amino-acid metabolism
0.001 0.929 0.069
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.930 0.070
E79 Disorders of purine and pyrimidine metabolism
0.001 0.931 0.068
C21.0 Anus, unspecified
0.000 0.931 0.069
R31 Unspecified haematuria
0.068 0.932 0.000
E83.4 Disorders of magnesium metabolism
0.060 0.932 0.008
C21.1 Anal canal
0.000 0.932 0.068
E72 Other disorders of amino-acid metabolism
0.001 0.932 0.066
E88.9 Metabolic disorder, unspecified
0.000 0.933 0.067
E26.8 Other hyperaldosteronism
0.000 0.934 0.066
E26.1 Secondary hyperaldosteronism
0.000 0.934 0.066
E29.1 Testicular hypofunction
0.000 0.934 0.066
E34.0 Carcinoid syndrome
0.000 0.935 0.065
M45.X6 Ankylosing spondylitis (Lumbar region)
0.065 0.935 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.935 0.065
M45.X2 Ankylosing spondylitis (Cervical region)
0.065 0.935 0.000
E75.5 Other lipid storage disorders
0.001 0.936 0.063
E78.4 Other hyperlipidaemia
0.000 0.937 0.063
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.937 0.062
I83.1 Varicose veins of lower extremities with inflammation
0.062 0.937 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.939 0.061
E85.4 Organ-limited amyloidosis
0.000 0.939 0.060
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.061 0.939 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.061 0.939 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.061 0.939 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.061 0.939 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.061 0.939 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.061 0.939 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.940 0.059
E75.2 Other sphingolipidosis
0.001 0.941 0.058
C17.9 Small intestine, unspecified
0.000 0.941 0.059
C17.2 Ileum
0.000 0.941 0.058
E26.9 Hyperaldosteronism, unspecified
0.001 0.942 0.058
E75.6 Lipid storage disorder, unspecified
0.001 0.942 0.057
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.942 0.057
E75.3 Sphingolipidosis, unspecified
0.001 0.942 0.057
E75.1 Other gangliosidosis
0.001 0.942 0.057
E75.0 GM2 gangliosidosis
0.001 0.942 0.057
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.943 0.056
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.943 0.056
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.943 0.056
E74.2 Disorders of galactose metabolism
0.001 0.943 0.056
E74.1 Disorders of fructose metabolism
0.001 0.943 0.056
E85.3 Secondary systemic amyloidosis
0.001 0.944 0.055
E74.0 Glycogen storage disease
0.001 0.945 0.054
E22.8 Other hyperfunction of pituitary gland
0.000 0.946 0.054
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.946 0.054
E23.1 Drug-induced hypopituitarism
0.000 0.946 0.054
E85.8 Other amyloidosis
0.001 0.946 0.053
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.946 0.053
E71.3 Disorders of fatty-acid metabolism
0.001 0.946 0.052
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.946 0.052
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.946 0.052
E71.0 Maple-syrup-urine disease
0.001 0.946 0.052
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.946 0.052
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.946 0.052
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.946 0.052
E76.2 Other mucopolysaccharidoses
0.001 0.946 0.052
E76.1 Mucopolysaccharidosis, type II
0.001 0.946 0.052
E76.0 Mucopolysaccharidosis, type I
0.001 0.946 0.052
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.946 0.052
E77.8 Other disorders of glycoprotein metabolism
0.001 0.946 0.052
E77.1 Defects in glycoprotein degradation
0.001 0.946 0.052
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.946 0.052
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.947 0.053
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.947 0.053
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.947 0.053
C26.8 Overlapping lesion of digestive system
0.000 0.947 0.053
C26.1 Spleen
0.000 0.947 0.053
E73.8 Other lactose intolerance
0.001 0.947 0.052
E73.1 Secondary lactase deficiency
0.001 0.947 0.052
E73.0 Congenital lactase deficiency
0.001 0.947 0.052
E88.8 Other specified metabolic disorders
0.001 0.947 0.052
E84.8 Cystic fibrosis with other manifestations
0.001 0.947 0.052
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.947 0.052
I73.9 Peripheral vascular disease, unspecified
0.000 0.948 0.052
E73.9 Lactose intolerance, unspecified
0.001 0.948 0.051
I73 Other peripheral vascular diseases
0.000 0.949 0.051
E22.1 Hyperprolactinaemia
0.000 0.949 0.051
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.949 0.050
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.949 0.050
E70.2 Disorders of tyrosine metabolism
0.001 0.949 0.050
E70.1 Other hyperphenylalaninaemias
0.001 0.949 0.050
E70.0 Classical phenylketonuria
0.001 0.949 0.050
C22.7 Other specified carcinomas of liver
0.000 0.949 0.050
C22.4 Other sarcomas of liver
0.000 0.949 0.050
C22.3 Angiosarcoma of liver
0.000 0.949 0.050
C22.2 Hepatoblastoma
0.000 0.949 0.050
I77 Other disorders of arteries and arterioles
0.000 0.950 0.050
E84.9 Cystic fibrosis, unspecified
0.001 0.950 0.049
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.950 0.049
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.950 0.049
E79.1 Lesch-Nyhan syndrome
0.001 0.950 0.049
C22.9 Liver, unspecified
0.000 0.951 0.049
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.951 0.048
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.951 0.048
E72.5 Disorders of glycine metabolism
0.001 0.951 0.048
E72.4 Disorders of ornithine metabolism
0.001 0.951 0.048
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.951 0.048
E72.2 Disorders of urea cycle metabolism
0.001 0.951 0.048
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.952 0.048
C25.0 Head of pancreas
0.000 0.952 0.048
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.952 0.048
I77.6 Arteritis, unspecified
0.000 0.952 0.048
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.047 0.953 0.000
E72.0 Disorders of amino-acid transport
0.001 0.953 0.046
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.953 0.047
E70.3 Albinism
0.001 0.953 0.046
C22.1 Intrahepatic bile duct carcinoma
0.000 0.953 0.047
E88.3 Tumour lysis syndrome
0.001 0.954 0.046
E04 Other non-toxic goitre
0.003 0.954 0.043
C24.1 Ampulla of Vater
0.001 0.954 0.045
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.955 0.044
E78.8 Other disorders of lipoprotein metabolism
0.000 0.955 0.045
I73.0 Raynaud's syndrome
0.000 0.955 0.045
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.956 0.043
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.956 0.043
I77.8 Other specified disorders of arteries and arterioles
0.000 0.957 0.043
I72 Other aneurysm
0.000 0.957 0.043
I74 Arterial embolism and thrombosis
0.000 0.957 0.043
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.958 0.042
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.959 0.040
I74.5 Embolism and thrombosis of iliac artery
0.000 0.960 0.040
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.960 0.040
I73.8 Other specified peripheral vascular diseases
0.000 0.961 0.039
I70 Atherosclerosis
0.000 0.961 0.038
I77.3 Arterial fibromuscular dysplasia
0.000 0.962 0.038
C26.9 Ill-defined sites within the digestive system
0.001 0.962 0.037
E53.8 Deficiency of other specified B group vitamins
0.000 0.962 0.038
I72.4 Aneurysm of artery of lower extremity
0.000 0.963 0.037
E23.2 Diabetes insipidus
0.000 0.963 0.037
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.963 0.037
I77.2 Rupture of artery
0.000 0.963 0.037
E22.0 Acromegaly and pituitary gigantism
0.000 0.963 0.036
E23.6 Other disorders of pituitary gland
0.000 0.964 0.036
I77.5 Necrosis of artery
0.000 0.964 0.036
I77.4 Coeliac artery compression syndrome
0.000 0.964 0.036
I77.1 Stricture of artery
0.000 0.964 0.036
E85.9 Amyloidosis, unspecified
0.001 0.964 0.035
E26.0 Primary hyperaldosteronism
0.001 0.964 0.035
E78.0 Pure hypercholesterolaemia
0.000 0.965 0.035
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.965 0.035
C26.0 Intestinal tract, part unspecified
0.000 0.966 0.034
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.966 0.034
I72.3 Aneurysm of iliac artery
0.000 0.966 0.034
I72.0 Aneurysm of carotid artery
0.000 0.966 0.034
I72.1 Aneurysm of artery of upper extremity
0.000 0.966 0.034
E04.8 Other specified non-toxic goitre
0.002 0.967 0.031
C16 Malignant neoplasm of stomach
0.000 0.967 0.033
C18 Malignant neoplasm of colon
0.000 0.968 0.032
E80.2 Other porphyria
0.001 0.969 0.030
C18.1 Appendix
0.000 0.969 0.031
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.969 0.031
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.969 0.031
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.969 0.031
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.969 0.031
I72.9 Aneurysm of unspecified site
0.000 0.969 0.031
E11.9 Without complications
0.000 0.970 0.030
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.970 0.030
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.970 0.029
E80.5 Crigler-Najjar syndrome
0.001 0.970 0.029
E80.3 Defects of catalase and peroxydase
0.001 0.970 0.029
E80.0 Hereditary erythropoietic porphyria
0.001 0.970 0.029
I70.8 Atherosclerosis of other arteries
0.000 0.971 0.029
C18.9 Colon, unspecified
0.000 0.971 0.029
I70.1 Atherosclerosis of renal artery
0.000 0.971 0.029
E27 Other disorders of adrenal gland
0.000 0.971 0.029
I72.8 Aneurysm of other specified arteries
0.000 0.971 0.029
I72.2 Aneurysm of renal artery
0.000 0.972 0.028
I70.0 Atherosclerosis of aorta
0.000 0.972 0.028
I70.9 Generalised and unspecified atherosclerosis
0.000 0.973 0.027
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.974 0.026
K90-K93 Other diseases of the digestive system
0.000 0.974 0.026
E66 Obesity
0.000 0.974 0.026
I79.1 Aortitis in diseases classified elsewhere
0.000 0.975 0.025
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.975 0.025

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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