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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs281379
log Bayes Factor = 19.5324
Chromosome 19   position 49,214,274  (GRCh37) Explore rs281379 on Ensembl!
Variant rs281379 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.000 1.000
K80 Cholelithiasis
0.000 0.000 1.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.000 1.000
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.000 1.000
K29 Gastritis and duodenitis
0.000 0.000 1.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.001 0.999
K26 Duodenal ulcer
0.000 0.001 0.999
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.002 0.998
K29.8 Duodenitis
0.000 0.003 0.997
K82 Other diseases of gallbladder
0.000 0.003 0.997
K65-K67 Diseases of peritoneum
0.000 0.011 0.989
K29.5 Chronic gastritis, unspecified
0.000 0.015 0.985
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.017 0.983
K82.8 Other specified diseases of gallbladder
0.000 0.018 0.982
K29.0 Acute haemorrhagic gastritis
0.000 0.021 0.979
I80 Phlebitis and thrombophlebitis
0.000 0.023 0.977
K70-K77 Diseases of liver
0.000 0.024 0.976
K82.4 Cholesterolosis of gallbladder
0.000 0.026 0.974
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.028 0.972
E78.0 Pure hypercholesterolaemia
0.000 0.030 0.970
I83 Varicose veins of lower extremities
0.000 0.030 0.970
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.031 0.969
K66 Other disorders of peritoneum
0.000 0.038 0.962
K70 Alcoholic liver disease
0.000 0.041 0.959
I10-I15 Hypertensive diseases
0.000 0.044 0.956
K31 Other diseases of stomach and duodenum
0.000 0.051 0.949
K70.3 Alcoholic cirrhosis of liver
0.000 0.052 0.948
Chapter IX Diseases of the circulatory system
0.000 0.057 0.943
K83 Other diseases of biliary tract
0.000 0.059 0.941
K31.8 Other specified diseases of stomach and duodenum
0.000 0.064 0.936
K66.0 Peritoneal adhesions
0.000 0.067 0.933
K74 Fibrosis and cirrhosis of liver
0.000 0.080 0.920
K29.4 Chronic atrophic gastritis
0.000 0.084 0.916
K65 Peritonitis
0.000 0.091 0.909
K83.0 Cholangitis
0.000 0.095 0.905
K83.1 Obstruction of bile duct
0.000 0.102 0.898
K66.8 Other specified disorders of peritoneum
0.000 0.119 0.881
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.129 0.871
K82.9 Disease of gallbladder, unspecified
0.000 0.143 0.857
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.150 0.850
K74.0 Hepatic fibrosis
0.000 0.155 0.845
I85 Oesophageal varices
0.000 0.161 0.839
K31.9 Disease of stomach and duodenum, unspecified
0.000 0.162 0.838
K65.8 Other peritonitis
0.000 0.163 0.837
K26.4 Chronic or unspecified with haemorrhage
0.000 0.172 0.828
K26.7 Chronic without haemorrhage or perforation
0.000 0.183 0.817
K74.6 Other and unspecified cirrhosis of liver
0.000 0.183 0.817
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.201 0.799
K26.1 Acute with perforation
0.000 0.212 0.788
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.215 0.785
K73 Chronic hepatitis, not elsewhere classified
0.000 0.218 0.782
I88 Nonspecific lymphadenitis
0.000 0.219 0.781
K29.2 Alcoholic gastritis
0.000 0.219 0.781
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.233 0.767
K23 Disorders of oesophagus in diseases classified elsewhere
0.000 0.235 0.765
K27 Peptic ulcer, site unspecified
0.000 0.238 0.762
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.239 0.761
I15 Secondary hypertension
0.000 0.242 0.758
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.252 0.748
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.258 0.742
K26.2 Acute with both haemorrhage and perforation
0.000 0.260 0.740
I85.9 Oesophageal varices without bleeding
0.000 0.266 0.734
K31.2 Hourglass stricture and stenosis of stomach
0.000 0.272 0.728
K31.4 Gastric diverticulum
0.000 0.273 0.727
K74.5 Biliary cirrhosis, unspecified
0.000 0.281 0.719
K70.1 Alcoholic hepatitis
0.000 0.281 0.719
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.000 0.282 0.718
K80.3 Calculus of bile duct with cholangitis
0.000 0.283 0.717
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.283 0.717
K29.9 Gastroduodenitis, unspecified
0.000 0.283 0.717
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.286 0.714
I26 Pulmonary embolism
0.000 0.290 0.710
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.291 0.709
I72 Other aneurysm
0.000 0.293 0.707
K66.9 Disorder of peritoneum, unspecified
0.000 0.294 0.706
K29.3 Chronic superficial gastritis
0.000 0.295 0.705
K65.0 Acute peritonitis
0.000 0.299 0.701
K80.8 Other cholelithiasis
0.000 0.300 0.700
K82.3 Fistula of gallbladder
0.000 0.302 0.698
I82 Other venous embolism and thrombosis
0.000 0.308 0.692
K70.9 Alcoholic liver disease, unspecified
0.000 0.309 0.691
K31.0 Acute dilatation of stomach
0.000 0.312 0.688
I13 Hypertensive heart and renal disease
0.000 0.315 0.685
K83.9 Disease of biliary tract, unspecified
0.000 0.320 0.680
K83.5 Biliary cyst
0.000 0.325 0.675
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.326 0.674
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.329 0.671
K31.3 Pylorospasm, not elsewhere classified
0.000 0.329 0.670
K27.7 Chronic without haemorrhage or perforation
0.000 0.333 0.667
K77 Liver disorders in diseases classified elsewhere
0.000 0.334 0.666
K74.4 Secondary biliary cirrhosis
0.000 0.340 0.660
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.340 0.660
I28 Other diseases of pulmonary vessels
0.000 0.342 0.658
K50-K52 Noninfective enteritis and colitis
0.000 0.345 0.655
K70.4 Alcoholic hepatic failure
0.000 0.347 0.653
K65.9 Peritonitis, unspecified
0.000 0.348 0.652
K76 Other diseases of liver
0.000 0.350 0.650
I00-I02 Acute rheumatic fever
0.000 0.356 0.644
I72.4 Aneurysm of artery of lower extremity
0.000 0.357 0.643
K26.0 Acute with haemorrhage
0.000 0.359 0.641
I15.9 Seconday hypertension, unspecified
0.000 0.361 0.639
I71 Aortic aneurysm and dissection
0.000 0.362 0.638
K74.1 Hepatic sclerosis
0.000 0.366 0.634
K28 Gastrojejunal ulcer
0.000 0.366 0.634
I60-I69 Cerebrovascular diseases
0.000 0.374 0.626
K50 Crohn's disease [regional enteritis]
0.000 0.376 0.624
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.377 0.623
I85.0 Oesophageal varices with bleeding
0.000 0.377 0.623
K31.6 Fistula of stomach and duodenum
0.000 0.379 0.621
K50.1 Crohn's disease of large intestine
0.000 0.381 0.619
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.384 0.616
I72.9 Aneurysm of unspecified site
0.000 0.396 0.604
K82.0 Obstruction of gallbladder
0.000 0.396 0.604
K23.8 Disorders of oesophagus in other diseases classified elsewhere
0.000 0.403 0.597
I74 Arterial embolism and thrombosis
0.000 0.405 0.595
K72 Hepatic failure, not elsewhere classified
0.000 0.406 0.594
K31.1 Adult hypertrophic pyloric stenosis
0.000 0.407 0.593
I72.0 Aneurysm of carotid artery
0.000 0.412 0.588
K73.9 Chronic hepatitis, unspecified
0.000 0.418 0.582
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.419 0.581
I61 Intracerebral haemorrhage
0.000 0.419 0.581
I63 Cerebral infarction
0.000 0.421 0.579
K71 Toxic liver disease
0.000 0.423 0.577
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.425 0.574
K82.2 Perforation of gallbladder
0.000 0.432 0.568
I15.1 Hypertension secondary to other renal disorders
0.000 0.432 0.568
K83.2 Perforation of bile duct
0.000 0.433 0.566
I28.8 Other specified diseases of pulmonary vessels
0.000 0.435 0.565
I70 Atherosclerosis
0.000 0.439 0.561
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.439 0.560
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.439 0.560
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.440 0.560
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.443 0.557
K83.4 Spasm of sphincter of Oddi
0.000 0.446 0.554
I88.8 Other nonspecific lymphadenitis
0.000 0.446 0.554
I72.2 Aneurysm of renal artery
0.000 0.447 0.553
K83.3 Fistula of bile duct
0.000 0.447 0.553
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.449 0.551
K29.1 Other acute gastritis
0.000 0.450 0.550
K23.1 Megaoesophagus in Chagas' disease
0.000 0.451 0.549
K23.0 Tuberculous oesophagitis
0.000 0.451 0.549
I87 Other disorders of veins
0.000 0.453 0.547
K27.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.453 0.547
K27.5 Chronic or unspecified with perforation
0.000 0.453 0.547
K27.4 Chronic or unspecified with haemorrhage
0.000 0.453 0.547
K27.2 Acute with both haemorrhage and perforation
0.000 0.453 0.547
K27.1 Acute with perforation
0.000 0.453 0.547
K27.0 Acute with haemorrhage
0.000 0.453 0.547
K70.0 Alcoholic fatty liver
0.000 0.453 0.547
I11 Hypertensive heart disease
0.000 0.454 0.546
I15.8 Other secondary hypertension
0.000 0.457 0.543
I15.2 Hypertension secondary to endocrine disorders
0.000 0.457 0.543
I82.0 Budd-Chiari syndrome
0.000 0.465 0.535
I82.2 Embolism and thrombosis of vena cava
0.000 0.467 0.533
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.469 0.531
I60 Subarachnoid haemorrhage
0.000 0.478 0.522
K26.3 Acute without haemorrhage or perforation
0.000 0.478 0.522
K26.5 Chronic or unspecified with perforation
0.000 0.478 0.522
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction
0.000 0.486 0.514
K87.1 Disorders of pancreas in diseases classified elsewhere
0.000 0.486 0.514
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere
0.000 0.486 0.514
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.486 0.514
K27.3 Acute without haemorrhage or perforation
0.000 0.487 0.513
K76.8 Other specified diseases of liver
0.000 0.487 0.513
K76.7 Hepatorenal syndrome
0.000 0.491 0.509
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.491 0.508
K67.3 Tuberculous peritonitis
0.000 0.491 0.508
K67.2 Syphilitic peritonitis
0.000 0.491 0.508
K67.1 Gonococcal peritonitis
0.000 0.491 0.508
K67.0 Chlamydial peritonitis
0.000 0.491 0.508
I77 Other disorders of arteries and arterioles
0.000 0.493 0.507
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.493 0.507
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.493 0.507
I86 Varicose veins of other sites
0.000 0.494 0.505
K74.3 Primary biliary cirrhosis
0.000 0.496 0.504
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.498 0.502
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.499 0.501
I82.1 Thrombophlebitis migrans
0.000 0.504 0.496
K85 Acute pancreatitis
0.000 0.504 0.495
I81 Portal vein thrombosis
0.000 0.508 0.492
I74.5 Embolism and thrombosis of iliac artery
0.000 0.508 0.492
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.509 0.491
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.509 0.491
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.509 0.491
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.509 0.491
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.509 0.491
K76.1 Chronic passive congestion of liver
0.000 0.511 0.489
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.514 0.486
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.518 0.482
K31.5 Obstruction of duodenum
0.000 0.520 0.480
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.522 0.478
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.524 0.476
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.524 0.476
I28.1 Aneurysm of pulmonary artery
0.000 0.528 0.472
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.528 0.472
K90-K93 Other diseases of the digestive system
0.000 0.528 0.472
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.529 0.471
I15.0 Renovascular hypertension
0.000 0.531 0.469
K80.4 Calculus of bile duct with cholecystitis
0.000 0.531 0.469
I70.0 Atherosclerosis of aorta
0.000 0.533 0.467
K76.5 Hepatic veno-occlusive disease
0.000 0.534 0.466
K76.4 Peliosis hepatis
0.000 0.534 0.466
K76.3 Infarction of liver
0.000 0.534 0.466
K76.2 Central haemorrhagic necrosis of liver
0.000 0.534 0.466
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.534 0.466
I63.9 Cerebral infarction, unspecified
0.000 0.534 0.466
I82.3 Embolism and thrombosis of renal vein
0.000 0.537 0.463
I02 Rheumatic chorea
0.000 0.538 0.462
I01 Rheumatic fever with heart involvement
0.000 0.538 0.462
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.540 0.460
K50.8 Other Crohn's disease
0.000 0.541 0.459
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.541 0.459
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.541 0.458
I72.8 Aneurysm of other specified arteries
0.000 0.542 0.458
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.542 0.457
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.542 0.457
I61.8 Other intracerebral haemorrhage
0.000 0.545 0.455
K28.7 Chronic without haemorrhage or perforation
0.000 0.545 0.454
K28.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.545 0.454
K28.5 Chronic or unspecified with perforation
0.000 0.545 0.454
K28.4 Chronic or unspecified with haemorrhage
0.000 0.545 0.454
K28.3 Acute without haemorrhage or perforation
0.000 0.545 0.454
K28.2 Acute with both haemorrhage and perforation
0.000 0.545 0.454
K28.1 Acute with perforation
0.000 0.545 0.454
K28.0 Acute with haemorrhage
0.000 0.545 0.454
K82.1 Hydrops of gallbladder
0.000 0.551 0.449
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.553 0.447
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.555 0.445
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.556 0.444
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.556 0.444
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.558 0.442
I70.1 Atherosclerosis of renal artery
0.000 0.560 0.440
K76.6 Portal hypertension
0.000 0.561 0.439
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.565 0.435
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.565 0.435
I77.8 Other specified disorders of arteries and arterioles
0.000 0.567 0.433
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.568 0.432
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.569 0.431
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.569 0.431
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.569 0.431
I00 Rheumatic fever without mention of heart involvement
0.000 0.570 0.430
K71.0 Toxic liver disease with cholestasis
0.000 0.576 0.424
I72.1 Aneurysm of artery of upper extremity
0.000 0.576 0.424
K72.9 Hepatic failure, unspecified
0.000 0.578 0.422
I77.6 Arteritis, unspecified
0.000 0.579 0.421
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.581 0.419
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.582 0.418
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.582 0.418
I72.3 Aneurysm of iliac artery
0.000 0.583 0.417
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.585 0.415
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.585 0.415
K71.9 Toxic liver disease, unspecified
0.000 0.586 0.414
K71.8 Toxic liver disease with other disorders of liver
0.000 0.586 0.414
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.586 0.414
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.586 0.414
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.586 0.414
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.586 0.414
K71.2 Toxic liver disease with acute hepatitis
0.000 0.586 0.414
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.588 0.412
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.590 0.409
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.594 0.406
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.594 0.406
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.595 0.405
K72.0 Acute and subacute hepatic failure
0.000 0.595 0.405
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.595 0.404
I70.9 Generalised and unspecified atherosclerosis
0.000 0.597 0.402
I69 Sequelae of cerebrovascular disease
0.000 0.600 0.400
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.601 0.399
I86.4 Gastric varices
0.000 0.602 0.398
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.605 0.395
I87.0 Postphlebitic syndrome
0.000 0.608 0.392
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.610 0.390
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.611 0.389
K35-K38 Diseases of appendix
0.000 0.613 0.387
K85.8 Other acute pancreatitis
0.000 0.613 0.387
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.615 0.385
I73 Other peripheral vascular diseases
0.000 0.617 0.383
I12 Hypertensive renal disease
0.000 0.620 0.380
K85.1 Biliary acute pancreatitis
0.000 0.623 0.377
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.623 0.377
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.624 0.376
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.625 0.375
I82.8 Embolism and thrombosis of other specified veins
0.000 0.626 0.374
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.627 0.373
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.628 0.371
K25 Gastric ulcer
0.000 0.628 0.372
I69.3 Sequelae of cerebral infarction
0.000 0.629 0.371
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.630 0.370
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.632 0.368
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.633 0.367
I86.2 Pelvic varices
0.000 0.634 0.365
I77.5 Necrosis of artery
0.000 0.636 0.364
I77.4 Coeliac artery compression syndrome
0.000 0.636 0.364
I86.0 Sublingual varices
0.000 0.637 0.362
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.638 0.362
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.641 0.359
I87.9 Disorder of vein, unspecified
0.000 0.641 0.359
K72.1 Chronic hepatic failure
0.000 0.642 0.358
I86.8 Varicose veins of other specified sites
0.000 0.645 0.354
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.647 0.353
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.649 0.351
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.650 0.350
K50.9 Crohn's disease, unspecified
0.000 0.651 0.349
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.655 0.345
I86.3 Vulval varices
0.000 0.660 0.340
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.660 0.339
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.001 0.661 0.338
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.662 0.338
I77.3 Arterial fibromuscular dysplasia
0.000 0.662 0.338
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.665 0.335
I60.8 Other subarachnoid haemorrhage
0.000 0.666 0.334
K29.6 Other gastritis
0.000 0.668 0.332
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.669 0.331
I01.8 Other acute rheumatic heart disease
0.000 0.669 0.331
I01.2 Acute rheumatic myocarditis
0.000 0.669 0.331
I01.1 Acute rheumatic endocarditis
0.000 0.669 0.331
I01.0 Acute rheumatic pericarditis
0.000 0.669 0.331
I02.9 Rheumatic chorea without heart involvement
0.000 0.669 0.331
I02.0 Rheumatic chorea with heart involvement
0.000 0.669 0.331
K85.3 Drug-induced acute pancreatitis
0.000 0.669 0.331
I70.8 Atherosclerosis of other arteries
0.000 0.669 0.330
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.669 0.330
I78 Diseases of capillaries
0.000 0.670 0.330
I65.1 Occlusion and stenosis of basilar artery
0.000 0.671 0.329
I79.1 Aortitis in diseases classified elsewhere
0.000 0.671 0.329
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.671 0.329
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.671 0.329
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.674 0.326
I95 Hypotension
0.000 0.674 0.326
K91.3 Postoperative intestinal obstruction
0.000 0.675 0.325
K40-K46 Hernia
0.000 0.678 0.322
K85.0 Idiopathic acute pancreatitis
0.000 0.679 0.321
I63.8 Other cerebral infarction
0.000 0.679 0.321
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.680 0.320
I62 Other nontraumatic intracranial haemorrhage
0.000 0.681 0.319
K91.4 Colostomy and enterostomy malfunction
0.000 0.682 0.318
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.684 0.316
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.684 0.315
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.688 0.312
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.688 0.312
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.689 0.311
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.690 0.309
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.690 0.309
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.690 0.309
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.691 0.309
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.691 0.309
I98.0 Cardiovascular syphilis
0.000 0.691 0.309
K91.5 Postcholecystectomy syndrome
0.000 0.692 0.308
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.692 0.307
K25.3 Acute without haemorrhage or perforation
0.000 0.696 0.304
K25.5 Chronic or unspecified with perforation
0.000 0.696 0.304
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.697 0.303
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.697 0.303
K91.1 Postgastric surgery syndromes
0.000 0.698 0.302
I87.1 Compression of vein
0.000 0.699 0.301
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.700 0.299
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.700 0.299
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.700 0.299
K36 Other appendicitis
0.000 0.701 0.299
I05-I09 Chronic rheumatic heart diseases
0.000 0.702 0.298
I77.0 Arteriovenous fistula, acquired
0.000 0.703 0.297
K66.1 Haemoperitoneum
0.002 0.703 0.295
K43 Ventral hernia
0.000 0.704 0.296
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.708 0.292
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.709 0.291
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.711 0.289
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.711 0.289
I73.8 Other specified peripheral vascular diseases
0.000 0.711 0.289
I71.0 Dissection of aorta [any part]
0.000 0.713 0.287
I95.2 Hypotension due to drugs
0.000 0.714 0.286
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.715 0.285
K76.9 Liver disease, unspecified
0.000 0.715 0.284
K85.9 Acute pancreatitis, unspecified
0.000 0.723 0.277
K75 Other inflammatory liver diseases
0.000 0.726 0.274
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.728 0.272
K83.8 Other specified diseases of biliary tract
0.000 0.731 0.269
I89.1 Lymphangitis
0.000 0.731 0.269
K41 Femoral hernia
0.000 0.731 0.269
I68.0 Cerebral amyloid angiopathy
0.000 0.732 0.268
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.733 0.267
K25.2 Acute with both haemorrhage and perforation
0.000 0.733 0.266
K25.1 Acute with perforation
0.000 0.733 0.266
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.734 0.266
I87.8 Other specified disorders of veins
0.000 0.734 0.266
I95.0 Idiopathic hypotension
0.000 0.734 0.266
K50.0 Crohn's disease of small intestine
0.000 0.736 0.264
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.737 0.262
I89.0 Lymphoedema, not elsewhere classified
0.000 0.738 0.262
I77.2 Rupture of artery
0.000 0.741 0.259
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.741 0.259
I73.9 Peripheral vascular disease, unspecified
0.000 0.743 0.257
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.745 0.255
K85.2 Alcohol-induced acute pancreatitis
0.000 0.747 0.253
I62.1 Nontraumatic extradural haemorrhage
0.000 0.754 0.246
K25.0 Acute with haemorrhage
0.000 0.754 0.246
I78.8 Other diseases of capillaries
0.000 0.756 0.244
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.757 0.243
K93.1 Megacolon in Chagas' disease
0.000 0.757 0.243
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.757 0.243
K25.7 Chronic without haemorrhage or perforation
0.000 0.758 0.242
I99 Other and unspecified disorders of circulatory system
0.000 0.762 0.238
I74.8 Embolism and thrombosis of other arteries
0.001 0.762 0.237
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.763 0.237
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.764 0.235
I95.8 Other hypotension
0.000 0.764 0.235
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.765 0.234
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.766 0.234
K75.0 Abscess of liver
0.000 0.766 0.234
N80.0 Endometriosis of uterus
0.000 0.768 0.232
I78.9 Disease of capillaries, unspecified
0.000 0.771 0.229
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.771 0.228
I12.9 Hypertensive renal disease without renal failure
0.000 0.771 0.229
K25.4 Chronic or unspecified with haemorrhage
0.000 0.772 0.228
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.775 0.225
K52 Other non-infective gastro-enteritis and colitis
0.000 0.778 0.222
I07 Rheumatic tricuspid valve diseases
0.000 0.781 0.219
K38 Other diseases of appendix
0.000 0.781 0.219
K46 Unspecified abdominal hernia
0.000 0.786 0.214
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.787 0.212
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.787 0.212
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.787 0.212
K43.4 Parastomal hernia with gangrene
0.000 0.787 0.212
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.787 0.212
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.787 0.212
K43.1 Ventral hernia with gangrene
0.000 0.787 0.212
I77.1 Stricture of artery
0.000 0.789 0.211
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.791 0.209
I06 Rheumatic aortic valve diseases
0.000 0.791 0.209
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.796 0.204
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.796 0.203
I27 Other pulmonary heart diseases
0.000 0.796 0.204
I09 Other rheumatic heart diseases
0.000 0.803 0.197
K75.2 Nonspecific reactive hepatitis
0.000 0.803 0.197
K75.1 Phlebitis of portal vein
0.000 0.803 0.197
N80 Endometriosis
0.000 0.804 0.196
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.805 0.195
K35 Acute appendicitis
0.000 0.805 0.195
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.805 0.195
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.807 0.193
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.807 0.193
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.808 0.192
K37 Unspecified appendicitis
0.000 0.813 0.187
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.814 0.186
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.818 0.181
I95.9 Hypotension, unspecified
0.000 0.822 0.178
N80.5 Endometriosis of intestine
0.000 0.823 0.177
I27.9 Pulmonary heart disease, unspecified
0.000 0.824 0.176
N80.8 Other endometriosis
0.000 0.826 0.174
I05 Rheumatic mitral valve diseases
0.000 0.826 0.174
K21 Gastro-oesophageal reflux disease
0.000 0.828 0.172
K45 Other abdominal hernia
0.000 0.828 0.171
K52.1 Toxic gastro-enteritis and colitis
0.000 0.829 0.171
N80.2 Endometriosis of Fallopian tube
0.000 0.830 0.170
N80.1 Endometriosis of ovary
0.000 0.833 0.167
K35.2 Acute appendicitis with generalized peritonitis
0.000 0.833 0.167
I70.80 Atherosclerosis of other arteries (without gangrene)
0.001 0.834 0.165
K90 Intestinal malabsorption
0.000 0.835 0.165
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.835 0.165
N80.4 Endometriosis of rectovaginal septum and vagina
0.000 0.835 0.165
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.836 0.164
I07.1 Tricuspid insufficiency
0.000 0.837 0.163
K38.1 Appendicular concretions
0.000 0.838 0.162
K52.3 Indeterminate colitis
0.000 0.839 0.161
I97.0 Postcardiotomy syndrome
0.000 0.840 0.160
I07.9 Tricuspid valve disease, unspecified
0.000 0.843 0.157
I07.8 Other tricuspid valve diseases
0.000 0.843 0.157
I07.2 Tricuspid stenosis with insufficiency
0.000 0.843 0.157
I07.0 Tricuspid stenosis
0.000 0.843 0.157
K35.1 Acute appendicitis with peritoneal abscess
0.000 0.843 0.157
K38.3 Fistula of appendix
0.000 0.843 0.157
I06.0 Rheumatic aortic stenosis
0.000 0.843 0.157
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.844 0.156
K38.0 Hyperplasia of appendix
0.000 0.844 0.155
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.845 0.155
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.845 0.155
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.846 0.154
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.848 0.152
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.849 0.151
I06.8 Other rheumatic aortic valve diseases
0.000 0.850 0.150
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.850 0.150
K75.4 Autoimmune hepatitis
0.000 0.850 0.150
K38.9 Disease of appendix, unspecified
0.000 0.852 0.148
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.854 0.146
I27.1 Kyphoscoliotic heart disease
0.000 0.854 0.146
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.855 0.144
I06.1 Rheumatic aortic insufficiency
0.000 0.857 0.143
I09.8 Other specified rheumatic heart diseases
0.000 0.858 0.141
I09.2 Chronic rheumatic pericarditis
0.000 0.858 0.141
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.858 0.141
I09.0 Rheumatic myocarditis
0.000 0.858 0.141
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.859 0.140
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.860 0.139
K38.2 Diverticulum of appendix
0.000 0.861 0.139
I97.1 Other functional disturbances following cardiac surgery
0.000 0.862 0.138
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.862 0.137
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.863 0.136
I86.1 Scrotal varices
0.000 0.865 0.135

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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