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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2814982
log Bayes Factor = 11.8908
Chromosome 6   position 34,546,560  (GRCh37) Explore rs2814982 on Ensembl!
Variant rs2814982 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M50-M54 Other dorsopathies
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M51 Other intervertebral disk disorders
0.999 0.001 0.000
M54 Dorsalgia
0.999 0.001 0.000
M51.2 Other specified intervertebral disk displacement
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
Chapter X Diseases of the respiratory system
0.996 0.004 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.996 0.004 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.993 0.007 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.992 0.008 0.000
M06.9 Rheumatoid arthritis, unspecified
0.992 0.008 0.000
M54.9 Dorsalgia, unspecified
0.988 0.012 0.000
M45-M49 Spondylopathies
0.987 0.013 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.983 0.017 0.000
M15-M19 Arthrosis
0.983 0.017 0.000
M16 Coxarthrosis [arthrosis of hip]
0.978 0.022 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.978 0.022 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.975 0.025 0.000
M16.0 Primary coxarthrosis, bilateral
0.974 0.026 0.000
E65-E68 Obesity and other hyperalimentation
0.974 0.026 0.000
M40-M43 Deforming dorsopathies
0.968 0.032 0.000
Chapter VIII Diseases of the ear and mastoid process
0.968 0.032 0.000
M48 Other spondylopathies
0.966 0.034 0.000
E66 Obesity
0.962 0.038 0.000
J09-J18 Influenza and pneumonia
0.960 0.040 0.000
H65-H75 Diseases of middle ear and mastoid
0.960 0.040 0.000
J95-J99 Other diseases of the respiratory system
0.958 0.042 0.000
E66.9 Obesity, unspecified
0.953 0.047 0.000
E50-E64 Other nutritional deficiencies
0.948 0.052 0.000
H74 Other disorders of middle ear and mastoid
0.934 0.066 0.000
M48.0 Spinal stenosis
0.934 0.066 0.000
J98 Other respiratory disorders
0.929 0.071 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.927 0.073 0.000
H73 Other disorders of tympanic membrane
0.927 0.073 0.000
M43 Other deforming dorsopathies
0.923 0.077 0.000
J98.4 Other disorders of lung
0.922 0.078 0.000
Chapter XXII Codes for special purposes
0.919 0.081 0.000
M54.2 Cervicalgia
0.915 0.085 0.000
M07 Psoriatic and enteropathic arthropathies
0.913 0.087 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.910 0.090 0.000
M47 Spondylosis
0.906 0.094 0.000
M54.3 Sciatica
0.906 0.094 0.000
H73.8 Other specified disorders of tympanic membrane
0.903 0.097 0.000
Q80-Q89 Other congenital malformations
0.902 0.098 0.000
Chapter IX Diseases of the circulatory system
0.901 0.099 0.000
J84 Other interstitial pulmonary diseases
0.899 0.101 0.000
E53 Deficiency of other B group vitamins
0.897 0.103 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.895 0.105 0.000
J18 Pneumonia, organism unspecified
0.895 0.105 0.000
E20-E35 Disorders of other endocrine glands
0.895 0.105 0.000
Y48 Anaesthetics and therapeutic gases
0.894 0.106 0.000
J81 Pulmonary oedema
0.888 0.112 0.000
M54.4 Lumbago with sciatica
0.887 0.113 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.879 0.121 0.000
M48.06 Spinal stenosis (Lumbar region)
0.876 0.124 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.874 0.126 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.868 0.132 0.000
M43.1 Spondylolisthesis
0.867 0.133 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.866 0.134 0.000
M53 Other dorsopathies, not elsewhere classified
0.864 0.136 0.000
I46 Cardiac arrest
0.863 0.137 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.862 0.138 0.000
I30-I52 Other forms of heart disease
0.861 0.139 0.000
E27 Other disorders of adrenal gland
0.859 0.141 0.000
M54.22 Cervicalgia (Cervical region)
0.859 0.141 0.000
Y42.5 Other oestrogens and progestogens
0.857 0.143 0.000
M06.3 Rheumatoid nodule
0.855 0.145 0.000
M70-M79 Other soft tissue disorders
0.854 0.146 0.000
I45 Other conduction disorders
0.853 0.147 0.000
E53.8 Deficiency of other specified B group vitamins
0.852 0.148 0.000
Q00-Q07 Congenital malformations of the nervous system
0.852 0.148 0.000
I46.0 Cardiac arrest with successful resuscitation
0.852 0.148 0.000
M07.3 Other psoriatic arthropathies
0.851 0.149 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.848 0.152 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.846 0.154 0.000
M16.3 Other dysplastic coxarthrosis
0.845 0.155 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.842 0.158 0.000
M47.8 Other spondylosis
0.842 0.158 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.842 0.158 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.840 0.160 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.839 0.161 0.000
M17 Gonarthrosis [arthrosis of knee]
0.837 0.163 0.000
I46.9 Cardiac arrest, unspecified
0.837 0.163 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.835 0.165 0.000
M05 Seropositive rheumatoid arthritis
0.834 0.166 0.000
I45.1 Other and unspecified right bundle-branch block
0.834 0.166 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.834 0.166 0.000
J20-J22 Other acute lower respiratory infections
0.833 0.167 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.832 0.168 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.832 0.168 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.832 0.168 0.000
Y57 Other and unspecified drugs and medicaments
0.830 0.170 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.830 0.170 0.000
M60-M63 Disorders of muscles
0.829 0.171 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.828 0.172 0.000
M06.0 Seronegative rheumatoid arthritis
0.828 0.172 0.000
M16.1 Other primary coxarthrosis
0.828 0.172 0.000
M40 Kyphosis and lordosis
0.826 0.174 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.821 0.179 0.000
M17.1 Other primary gonarthrosis
0.819 0.181 0.000
M79.6 Pain in limb
0.818 0.182 0.000
Q21 Congenital malformations of cardiac septa
0.808 0.192 0.000
I95 Hypotension
0.804 0.196 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.803 0.197 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.803 0.197 0.000
J14 Pneumonia due to Haemophilus influenzae
0.801 0.199 0.000
W75-W84 Other accidental threats to breathing
0.801 0.199 0.000
W00-W19 Falls
0.796 0.204 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.794 0.206 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.794 0.206 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.794 0.206 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.793 0.207 0.000
M54.39 Sciatica (Site unspecified)
0.792 0.208 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.791 0.209 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.789 0.211 0.000
E29 Testicular dysfunction
0.788 0.212 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.786 0.214 0.000
M47.86 Other spondylosis (Lumbar region)
0.784 0.216 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.782 0.218 0.000
J98.8 Other specified respiratory disorders
0.781 0.219 0.000
M54.37 Sciatica (Lumbosacral region)
0.781 0.219 0.000
Q50-Q56 Congenital malformations of genital organs
0.777 0.223 0.000
U89 Agent resistant to other and unspecified antibiotics
0.776 0.224 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.776 0.224 0.000
Q85 Phakomatoses, not elsewhere classified
0.774 0.225 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.774 0.225 0.000
J18.9 Pneumonia, unspecified
0.774 0.226 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.773 0.227 0.000
Y52 Agents primarily affecting the cardiovascular system
0.770 0.230 0.000
Y42.4 Oral contraceptives
0.769 0.231 0.000
E66.8 Other obesity
0.768 0.232 0.000
X50-X57 Overexertion, travel and privation
0.768 0.232 0.000
Q21.1 Atrial septal defect
0.767 0.233 0.000
M43.0 Spondylolysis
0.767 0.233 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.766 0.234 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.766 0.234 0.000
H74.4 Polyp of middle ear
0.766 0.234 0.000
Y00-Y09 Assault
0.765 0.235 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.765 0.235 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.764 0.236 0.000
J86 Pyothorax
0.763 0.237 0.000
U88 Agent resistant to multiple antibiotics
0.762 0.238 0.000
V01-V09 Pedestrian injured in transport accident
0.761 0.239 0.000
I45.3 Trifascicular block
0.761 0.239 0.000
Y45.1 Salicylates
0.761 0.239 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.761 0.239 0.000
Y59 Other and unspecified vaccines and biological substances
0.760 0.240 0.000
H70 Mastoiditis and related conditions
0.759 0.241 0.000
M06.4 Inflammatory polyarthropathy
0.759 0.241 0.000
I10-I15 Hypertensive diseases
0.759 0.241 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.758 0.242 0.000
H71 Cholesteatoma of middle ear
0.758 0.242 0.000
J90-J94 Other diseases of pleura
0.757 0.243 0.000
J85 Abscess of lung and mediastinum
0.756 0.244 0.000
Chapter XXI Factors influencing health status and contact with health services
0.752 0.248 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.752 0.248 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.751 0.249 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.751 0.249 0.000
I95.1 Orthostatic hypotension
0.751 0.249 0.000
J11 Influenza, virus not identified
0.750 0.249 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.750 0.250 0.000
E27.9 Disorder of adrenal gland, unspecified
0.750 0.250 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.749 0.251 0.000
E55 Vitamin D deficiency
0.749 0.251 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.747 0.253 0.000
Y45.8 Other analgesics and antipyretics
0.747 0.253 0.000
Y48.3 Local anaesthetics
0.747 0.253 0.000
Q05 Spina bifida
0.746 0.254 0.000
Q18 Other congenital malformations of face and neck
0.746 0.254 0.000
I26 Pulmonary embolism
0.746 0.254 0.000
M15 Polyarthrosis
0.746 0.254 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.746 0.254 0.000
J80 Adult respiratory distress syndrome
0.745 0.255 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.745 0.255 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.745 0.255 0.000
I60-I69 Cerebrovascular diseases
0.744 0.256 0.000
Y48.4 Anaesthetic, unspecified
0.743 0.257 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.742 0.258 0.000
X10-X19 Contact with heat and hot substances
0.741 0.259 0.000
J22 Unspecified acute lower respiratory infection
0.740 0.260 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.740 0.260 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.740 0.260 0.000
J98.2 Interstitial emphysema
0.739 0.261 0.000
M51.9 Intervertebral disk disorder, unspecified
0.738 0.262 0.000
Q65 Congenital deformities of hip
0.737 0.263 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.736 0.264 0.000
H74.0 Tympanosclerosis
0.735 0.265 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.734 0.265 0.000
M51.8 Other specified intervertebral disk disorders
0.734 0.266 0.000
J18.0 Bronchopneumonia, unspecified
0.733 0.267 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.732 0.268 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.731 0.269 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.729 0.271 0.000
Y57.8 Other drugs and medicaments
0.729 0.271 0.000
X58 Exposure to other specified factors
0.729 0.271 0.000
Q66 Congenital deformities of feet
0.728 0.272 0.000
M49 Spondylopathies in diseases classified elsewhere
0.728 0.272 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.728 0.272 0.000
V20-V29 Motorcycle rider injured in transport accident
0.728 0.272 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.727 0.273 0.000
J84.8 Other specified interstitial pulmonary diseases
0.727 0.273 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.726 0.274 0.000
M40.5 Lordosis, unspecified
0.726 0.274 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.725 0.275 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.725 0.275 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.724 0.276 0.000
M47.9 Spondylosis, unspecified
0.723 0.277 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.723 0.277 0.000
J18.1 Lobar pneumonia, unspecified
0.721 0.279 0.000
M79.5 Residual foreign body in soft tissue
0.721 0.279 0.000
M65-M68 Disorders of synovium and tendon
0.721 0.279 0.000
Y42.2 Antithyroid drugs
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M51.3 Other specified intervertebral disk degeneration
0.716 0.283 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.716 0.283 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.716 0.284 0.000
M54.8 Other dorsalgia
0.716 0.284 0.000
M54.0 Panniculitis affecting regions of neck and back
0.716 0.284 0.000
M12 Other specific arthropathies
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.716 0.284 0.000
T66-T78 Other and unspecified effects of external causes
0.716 0.284 0.000
M79.66 Pain in limb (Lower leg)
0.715 0.285 0.000
H74.1 Adhesive middle ear disease
0.715 0.285 0.000
M06.8 Other specified rheumatoid arthritis
0.715 0.285 0.000
M06.2 Rheumatoid bursitis
0.715 0.285 0.000
M06.1 Adult-onset Still's disease
0.715 0.285 0.000
X60-X84 Intentional self-harm
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
Q35-Q37 Cleft lip and cleft palate
0.714 0.286 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.714 0.286 0.000
J12 Viral pneumonia, not elsewhere classified
0.714 0.286 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.713 0.287 0.000
E61 Deficiency of other nutrient elements
0.713 0.287 0.000
V40-V49 Car occupant injured in transport accident
0.712 0.288 0.000
Y58 Bacterial vaccines
0.711 0.289 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.711 0.289 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.711 0.289 0.000
E29.1 Testicular hypofunction
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
M41 Scoliosis
0.710 0.290 0.000
M79.0 Rheumatism, unspecified
0.709 0.291 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.709 0.291 0.000
M45 Ankylosing spondylitis
0.709 0.291 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.708 0.292 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.708 0.292 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.708 0.292 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.708 0.292 0.000
Y43 Primarily systemic agents
0.708 0.292 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.708 0.292 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.708 0.292 0.000
W20-W49 Exposure to inanimate mechanical forces
0.708 0.292 0.000
I10 Essential (primary) hypertension
0.706 0.294 0.000
I45.4 Nonspecific intraventricular block
0.706 0.294 0.000
Y45.0 Opioids and related analgesics
0.706 0.294 0.000
S50-S59 Injuries to the elbow and forearm
0.706 0.294 0.000
V80-V89 Other land transport accidents
0.705 0.295 0.000
M91-M94 Chondropathies
0.705 0.295 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.704 0.296 0.000
M13 Other arthritis
0.704 0.296 0.000
H90-H95 Other disorders of ear
0.704 0.296 0.000
M79.67 Pain in limb (Ankle and foot)
0.704 0.296 0.000
E24 Cushing's syndrome
0.703 0.297 0.000
E27.8 Other specified disorders of adrenal gland
0.702 0.298 0.000
I45.6 Preexcitation syndrome
0.702 0.298 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.701 0.298 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.701 0.298 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.701 0.299 0.000
Q89 Other congenital malformations, not elsewhere classified
0.701 0.299 0.000
M17.3 Other posttraumatic gonarthrosis
0.701 0.299 0.000
M06.34 Rheumatoid nodule (Hand)
0.700 0.300 0.000
E67 Other hyperalimentation
0.698 0.302 0.000
E68 Sequelae of hyperalimentation
0.698 0.302 0.000
M54.5 Low back pain
0.698 0.302 0.000
X20-X29 Contact with venomous animals and plants
0.697 0.302 0.000
I50 Heart failure
0.697 0.303 0.000
M47.2 Other spondylosis with radiculopathy
0.696 0.304 0.000
J98.6 Disorders of diaphragm
0.696 0.304 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.696 0.304 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.695 0.305 0.000
E53.9 Vitamin B deficiency, unspecified
0.695 0.305 0.000
M42 Spinal osteochondrosis
0.694 0.306 0.000
M00-M03 Infectious arthropathies
0.694 0.306 0.000
Y48.2 Other and unspecified general anaesthetics
0.693 0.307 0.000
M48.9 Spondylopathy, unspecified
0.693 0.307 0.000
M48.8 Other specified spondylopathies
0.693 0.307 0.000
M48.4 Fatigue fracture of vertebra
0.693 0.307 0.000
M48.3 Traumatic spondylopathy
0.693 0.307 0.000
M48.2 Kissing spine
0.693 0.307 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.693 0.307 0.000
M62 Other disorders of muscle
0.693 0.307 0.000
S20-S29 Injuries to the thorax
0.692 0.308 0.000
E70-E90 Metabolic disorders
0.691 0.309 0.000
Q12 Congenital lens malformations
0.690 0.310 0.000
E66.1 Drug-induced obesity
0.689 0.310 0.000
M48.04 Spinal stenosis (Thoracic region)
0.689 0.311 0.000
M79.2 Neuralgia and neuritis, unspecified
0.689 0.311 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.689 0.311 0.000
J09 Influenza due to certain identified influenza virus
0.689 0.311 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.688 0.312 0.000
H68 Eustachian salpingitis and obstruction
0.688 0.312 0.000
H67 Otitis media in diseases classified elsewhere
0.688 0.312 0.000
J96 Respiratory failure, not elsewhere classified
0.687 0.313 0.000
S70-S79 Injuries to the hip and thigh
0.687 0.313 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.685 0.315 0.000
H66 Suppurative and unspecified otitis media
0.684 0.316 0.000
M54.1 Radiculopathy
0.684 0.316 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.684 0.316 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.683 0.317 0.000
U89.8 Agent resistant to other single specified antibiotic
0.682 0.318 0.000
J86.9 Pyothorax without fistula
0.682 0.318 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.680 0.319 0.000
W50-W64 Exposure to animate mechanical forces
0.680 0.320 0.000
H69 Other disorders of Eustachian tube
0.680 0.320 0.000
M76 Enthesopathies of lower limb, excluding foot
0.680 0.320 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.679 0.320 0.000
E63 Other nutritional deficiencies
0.679 0.320 0.000
E56 Other vitamin deficiencies
0.679 0.320 0.000
E51 Thiamine deficiency
0.679 0.320 0.000
E50 Vitamin A deficiency
0.679 0.320 0.000
E60 Dietary zinc deficiency
0.679 0.320 0.000
E59 Dietary selenium deficiency
0.679 0.320 0.000
E58 Dietary calcium deficiency
0.679 0.320 0.000
E54 Ascorbic acid deficiency
0.679 0.320 0.000
E52 Niacin deficiency [pellagra]
0.679 0.320 0.000
S51 Open wound of forearm
0.679 0.321 0.000
J15.1 Pneumonia due to Pseudomonas
0.679 0.321 0.000
M51.4 Schmorl's nodes
0.678 0.321 0.000
M79.69 Pain in limb (Site unspecified)
0.678 0.322 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.678 0.322 0.000
J93 Pneumothorax
0.676 0.324 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.673 0.327 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.672 0.328 0.000
Q17 Other congenital malformations of ear
0.672 0.328 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.672 0.328 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.671 0.329 0.000
M79.60 Pain in limb (Multiple sites)
0.671 0.329 0.000
Q05.9 Spina bifida, unspecified
0.670 0.330 0.000
T21 Burn and corrosion of trunk
0.670 0.330 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.670 0.330 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.670 0.330 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.670 0.330 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.670 0.330 0.000
M72 Fibroblastic disorders
0.669 0.331 0.000
I95.2 Hypotension due to drugs
0.669 0.331 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.668 0.331 0.000
J18.8 Other pneumonia, organism unspecified
0.668 0.332 0.000
Z71.3 Dietary counselling and surveillance
0.668 0.332 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.667 0.333 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.667 0.333 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.667 0.333 0.000
E65 Localised adiposity
0.667 0.333 0.000
Q25 Congenital malformations of great arteries
0.667 0.333 0.000
J98.3 Compensatory emphysema
0.666 0.334 0.000
M43.6 Torticollis
0.666 0.334 0.000
E87.7 Fluid overload
0.666 0.334 0.000
Y45.5 4-Aminophenol derivatives
0.665 0.335 0.000
Y45.4 Antirheumatics
0.665 0.335 0.000
X49.9 Unspecified place
0.665 0.335 0.000
I95.9 Hypotension, unspecified
0.665 0.335 0.000
H73.9 Disorder of tympanic membrane, unspecified
0.664 0.335 0.000
H73.1 Chronic myringitis
0.664 0.335 0.000
H73.0 Acute myringitis
0.664 0.335 0.000
Y57.6 Other diagnostic agents
0.663 0.337 0.000
M43.9 Deforming dorsopathy, unspecified
0.661 0.338 0.000
M43.8 Other specified deforming dorsopathies
0.661 0.338 0.000
M43.5 Other recurrent vertebral subluxation
0.661 0.338 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.661 0.338 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.661 0.338 0.000
M43.2 Other fusion of spine
0.661 0.338 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.661 0.339 0.000
W78 Inhalation of gastric contents
0.660 0.340 0.000
T23 Burn and corrosion of wrist and hand
0.659 0.341 0.000
S51.0 Open wound of elbow
0.658 0.342 0.000
I44 Atrioventricular and left bundle-branch block
0.658 0.342 0.000
I47 Paroxysmal tachycardia
0.657 0.343 0.000
Y42.7 Androgens and anabolic congeners
0.657 0.343 0.000
Z58 Problems related to physical environment
0.657 0.343 0.000
I61 Intracerebral haemorrhage
0.656 0.344 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.656 0.344 0.000
M54.27 Cervicalgia-Lumbosacral
0.656 0.344 0.000
M54.26 Cervicalgia-Lumbar
0.656 0.344 0.000
M54.25 Cervicalgia-Thoracolumbar
0.656 0.344 0.000
M54.24 Cervicalgia-Thoracic
0.656 0.344 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.656 0.344 0.000
M54.20 Cervicalgia-Mult site
0.656 0.344 0.000
X58.9 Unspecified place
0.655 0.345 0.000
Q83 Congenital malformations of breast
0.655 0.345 0.000
M07.6 Other enteropathic arthropathies
0.654 0.345 0.000
M07.5 Arthropathy in ulcerative colitis
0.654 0.345 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.654 0.345 0.000
M07.2 Psoriatic spondylitis
0.654 0.345 0.000
M07.1 Arthritis mutilans
0.654 0.345 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.654 0.345 0.000
M48.02 Spinal stenosis (Cervical region)
0.654 0.346 0.000
M40.56 Lordosis, unspecified (Lumbar region)
0.654 0.346 0.000
Chapter VII Diseases of the eye and adnexa
0.653 0.347 0.000
Y42.9 Other and unspecified hormone antagonists
0.652 0.348 0.000
Y42.1 Thyroid hormones and substitutes
0.652 0.348 0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns
0.652 0.348 0.000
W06 Fall involving bed
0.652 0.348 0.000
M16.7 Other secondary coxarthrosis
0.651 0.349 0.000
Q85.9 Phakomatosis, unspecified
0.651 0.349 0.000
M10 Gout
0.651 0.349 0.000
Y55.6 Antiasthmatics, not elsewhere classified
0.651 0.349 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.651 0.349 0.000
M47.89 Other spondylosis (Site unspecified)
0.650 0.350 0.000
E00-E07 Disorders of thyroid gland
0.650 0.350 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.650 0.350 0.000
M54.35 Sciatica (Thoracolumbar region)
0.650 0.350 0.000
M54.34 Sciatica-Thoracic
0.650 0.350 0.000
M54.33 Sciatica-Cervicothoracic
0.650 0.350 0.000
M54.32 Sciatica-Cervical
0.650 0.350 0.000
M54.31 Sciatica-Occipit-atl-axl
0.650 0.350 0.000
M54.30 Sciatica (Multiple sites in spine)
0.650 0.350 0.000
M79.68 Pain in limb (Other)
0.649 0.351 0.000
X45 Accidental poisoning by and exposure to alcohol
0.648 0.352 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.648 0.352 0.000
M86-M90 Other osteopathies
0.648 0.352 0.000
M79.1 Myalgia
0.648 0.352 0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.648 0.352 0.000
Y45.2 Propionic acid derivatives
0.648 0.352 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.648 0.352 0.000
M99 Biomechanical lesions, not elsewhere classified
0.648 0.352 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.647 0.352 0.000
Q65.8 Other congenital deformities of hip
0.647 0.353 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.647 0.353 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.647 0.353 0.000
Q84 Other congenital malformations of integument
0.647 0.353 0.000
Q81 Epidermolysis bullosa
0.647 0.353 0.000
Q80 Congenital ichthyosis
0.647 0.353 0.000
M95.0 Acquired deformity of nose
0.647 0.353 0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.646 0.354 0.000
I00-I02 Acute rheumatic fever
0.646 0.354 0.000
J84.0 Alveolar and parietoalveolar conditions
0.644 0.355 0.000
H93 Other disorders of ear, not elsewhere classified
0.644 0.356 0.000
E53.1 Pyridoxine deficiency
0.643 0.356 0.000
E53.0 Riboflavin deficiency
0.643 0.356 0.000
Z74 Problems related to care-provider dependency
0.643 0.357 0.000
Q82 Other congenital malformations of skin
0.642 0.358 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.642 0.358 0.000
M16.5 Other posttraumatic coxarthrosis
0.642 0.358 0.000
W17 Other fall from one level to another
0.642 0.358 0.000
J18.2 Hypostatic pneumonia, unspecified
0.641 0.358 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.641 0.358 0.000
E32 Diseases of thymus
0.641 0.358 0.000
E31 Polyglandular dysfunction
0.641 0.358 0.000
E30 Disorders of puberty, not elsewhere classified
0.641 0.358 0.000
E25 Adrenogenital disorders
0.641 0.358 0.000
Y48.5 Therapeutic gases
0.641 0.359 0.000
Y48.1 Parenteral anaesthetics
0.641 0.359 0.000
Y48.0 Inhaled anaesthetics
0.641 0.359 0.000
J94 Other pleural conditions
0.641 0.359 0.000
M43.02 Spondylolysis (Cervical region)
0.640 0.360 0.000
E20 Hypoparathyroidism
0.640 0.360 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.640 0.360 0.000
H55-H59 Other disorders of eye and adnexa
0.639 0.361 0.000
Q18.0 Sinus, fistula and cyst of branchial cleft
0.639 0.361 0.000
I95.0 Idiopathic hypotension
0.639 0.361 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.639 0.361 0.000
E40-E46 Malnutrition
0.639 0.361 0.000
J17 Pneumonia in diseases classified elsewhere
0.638 0.362 0.000
M14 Arthropathies in other diseases classified elsewhere
0.637 0.363 0.000
S30.0 Contusion of lower back and pelvis
0.637 0.363 0.000
M79.54 Residual foreign body in soft tissue (Hand)
0.637 0.363 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.636 0.364 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.636 0.364 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.636 0.364 0.000
M54.44 Lumbago with sciatica-Thoracic
0.636 0.364 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.636 0.364 0.000
M54.42 Lumbago with sciatica-Cervical
0.636 0.364 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.636 0.364 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.636 0.364 0.000
Y43.4 Immunosuppressive agents
0.636 0.364 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.636 0.364 0.000
M79.61 Pain in limb (Shoulder region)
0.635 0.365 0.000
Z59 Problems related to housing and economic circumstances
0.635 0.365 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.635 0.365 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.634 0.365 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.634 0.366 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.633 0.367 0.000
J85.2 Abscess of lung without pneumonia
0.631 0.369 0.000
I50.9 Heart failure, unspecified
0.631 0.369 0.000
J15.5 Pneumonia due to Escherichia coli
0.631 0.369 0.000
X50 Overexertion and strenuous or repetitive movements
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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