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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28362678
log Bayes Factor = 77.6599
Chromosome 6   position 32,362,745  (GRCh37) Explore rs28362678 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
E10.9 Without complications
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
C44.7 Skin of lower limb, including hip
1.000 0.000 0.000
K50-K52 Noninfective enteritis and colitis
0.999 0.001 0.000
K50 Crohn's disease [regional enteritis]
0.999 0.001 0.000
K50.1 Crohn's disease of large intestine
0.999 0.001 0.000
C44.4 Skin of scalp and neck
0.995 0.005 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.994 0.006 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.006 0.994
D86 Sarcoidosis
0.000 0.006 0.994
Z93.2 Ileostomy status
0.994 0.006 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.991 0.009 0.000
E10.1 With ketoacidosis
0.000 0.010 0.990
K51.4 Pseudopolyposis of colon
0.990 0.010 0.000
E10.3 With ophthalmic complications
0.000 0.011 0.989
D86.0 Sarcoidosis of lung
0.000 0.016 0.984
C44.2 Skin of ear and external auricular canal
0.980 0.020 0.000
C44.5 Skin of trunk
0.975 0.025 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.972 0.028 0.000
C44.6 Skin of upper limb, including shoulder
0.966 0.034 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.959 0.041 0.000
K51.8 Other ulcerative colitis
0.957 0.043 0.000
C44.0 Skin of lip
0.955 0.045 0.000
C83.3 Large cell (diffuse)
0.954 0.046 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.951 0.049 0.000
K51.2 Ulcerative (chronic) proctitis
0.950 0.050 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.937 0.063 0.000
K50.9 Crohn's disease, unspecified
0.925 0.075 0.000
E10-E14 Diabetes mellitus
0.000 0.079 0.921
D86.8 Sarcoidosis of other and combined sites
0.000 0.083 0.917
C82.0 Small cleaved cell, follicular
0.911 0.089 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.103 0.897
E16.2 Hypoglycaemia, unspecified
0.000 0.107 0.893
E16 Other disorders of pancreatic internal secretion
0.000 0.107 0.893
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.109 0.891
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.109 0.891
D51 Vitamin B12 deficiency anaemia
0.000 0.120 0.880
D50-D53 Nutritional anaemias
0.000 0.122 0.878
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.124 0.876
D80-D89 Certain disorders involving the immune mechanism
0.000 0.133 0.867
D50 Iron deficiency anaemia
0.000 0.143 0.857
K52 Other non-infective gastro-enteritis and colitis
0.855 0.145 0.000
D50.9 Iron deficiency anaemia, unspecified
0.000 0.145 0.855
E20-E35 Disorders of other endocrine glands
0.000 0.149 0.851
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.152 0.847
E27 Other disorders of adrenal gland
0.000 0.158 0.842
E10.8 With unspecified complications
0.000 0.158 0.842
E27.1 Primary adrenocortical insufficiency
0.000 0.161 0.839
K51.5 Mucosal proctocolitis
0.835 0.165 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.830 0.170 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.189 0.811
C82.3 Follicular lymphoma grade IIIa
0.798 0.202 0.000
C44.1 Skin of eyelid, including canthus
0.788 0.212 0.000
E10.4 With neurological complications
0.000 0.220 0.780
K90 Intestinal malabsorption
0.000 0.221 0.779
E10.0 With coma
0.000 0.226 0.774
C44.9 Malignant neoplasm of skin, unspecified
0.764 0.236 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.760 0.240 0.000
C83.1 Small cleaved cell (diffuse)
0.756 0.244 0.000
K52.1 Toxic gastro-enteritis and colitis
0.756 0.244 0.000
E10.6 With other specified complications
0.000 0.246 0.754
C85.1 B-cell lymphoma, unspecified
0.746 0.254 0.000
K50.8 Other Crohn's disease
0.739 0.261 0.000
E22 Hyperfunction of pituitary gland
0.000 0.262 0.738
K51.3 Ulcerative (chronic) rectosigmoiditis
0.730 0.270 0.000
C81 Hodgkin's disease
0.726 0.274 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.722 0.278 0.000
E16.1 Other hypoglycaemia
0.000 0.280 0.720
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E10.2 With renal complications
0.000 0.285 0.714
C82.2 Large cell, follicular
0.714 0.286 0.000
D86.3 Sarcoidosis of skin
0.000 0.287 0.713
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.287 0.713
C82.6 Cutaneous follicle centre lymphoma
0.711 0.289 0.000
C82.5 Diffuse follicle centre lymphoma
0.711 0.289 0.000
C82.4 Follicular lymphoma grade IIIb
0.711 0.289 0.000
K52.3 Indeterminate colitis
0.709 0.291 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.707 0.293 0.000
E14 Unspecified diabetes mellitus
0.000 0.298 0.702
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.302 0.698
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.697 0.303 0.000
C94 Other leukaemias of specified cell type
0.697 0.303 0.000
C93 Monocytic leukaemia
0.697 0.303 0.000
C86 Other specified types of T/NK-cell lymphoma
0.697 0.303 0.000
E24 Cushing's syndrome
0.000 0.306 0.694
C84 Peripheral and cutaneous T-cell lymphomas
0.692 0.308 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.309 0.691
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.310 0.689
C83.6 Undifferentiated (diffuse)
0.687 0.313 0.000
C83.5 Lymphoblastic (diffuse)
0.687 0.313 0.000
C83.4 Immunoblastic (diffuse)
0.687 0.313 0.000
C83.2 Mixed small and large cell (diffuse)
0.687 0.313 0.000
C95 Leukaemia of unspecified cell type
0.686 0.314 0.000
D52 Folate deficiency anaemia
0.000 0.315 0.685
E13 Other specified diabetes mellitus
0.000 0.317 0.683
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.682 0.318 0.000
C85.0 Lymphosarcoma
0.682 0.318 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.668 0.331 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.333 0.667
E27.2 Addisonian crisis
0.000 0.336 0.664
E12 Malnutrition-related diabetes mellitus
0.000 0.339 0.661
C83.7 Burkitt's tumour
0.660 0.340 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.348 0.652
E10.5 With peripheral circulatory complications
0.000 0.353 0.646
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.360 0.640
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.360 0.640
E16.4 Abnormal secretion of gastrin
0.000 0.360 0.640
E16.3 Increased secretion of glucagon
0.000 0.360 0.640
K51.1 Ulcerative (chronic) ileocolitis
0.640 0.360 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.361 0.639
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.369 0.631
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.369 0.631
D51.2 Transcobalamin II deficiency
0.000 0.369 0.631
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.369 0.631
K90.9 Intestinal malabsorption, unspecified
0.000 0.373 0.627
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.624 0.376 0.000
C88 Malignant immunoproliferative diseases
0.624 0.376 0.000
D82 Immunodeficiency associated with other major defects
0.000 0.378 0.621
D81 Combined immunodeficiencies
0.000 0.378 0.621
C90 Multiple myeloma and malignant plasma cell neoplasms
0.621 0.379 0.000
E20 Hypoparathyroidism
0.000 0.384 0.616
D50.1 Sideropenic dysphagia
0.000 0.386 0.614
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.390 0.610
E32 Diseases of thymus
0.000 0.390 0.610
E31 Polyglandular dysfunction
0.000 0.390 0.610
E30 Disorders of puberty, not elsewhere classified
0.000 0.390 0.610
E25 Adrenogenital disorders
0.000 0.390 0.610
D53 Other nutritional anaemias
0.000 0.391 0.609
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.394 0.606
E27.5 Adrenomedullary hyperfunction
0.000 0.396 0.604
E27.0 Other adrenocortical overactivity
0.000 0.396 0.604
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.601 0.399 0.000
C81.1 Nodular sclerosis
0.597 0.403 0.000
K90.8 Other intestinal malabsorption
0.000 0.410 0.590
E24.9 Cushing's syndrome, unspecified
0.000 0.419 0.581
E14.9 Without complications
0.000 0.420 0.580
E40-E46 Malnutrition
0.000 0.423 0.577
E21.0 Primary hyperparathyroidism
0.000 0.424 0.576
C85.7 Other specified types of non-Hodgkin's lymphoma
0.574 0.426 0.000
D55-D59 Haemolytic anaemias
0.000 0.431 0.568
E34 Other endocrine disorders
0.000 0.438 0.562
E27.8 Other specified disorders of adrenal gland
0.000 0.439 0.561
K90.3 Pancreatic steatorrhoea
0.000 0.441 0.559
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.441 0.559
K90.1 Tropical sprue
0.000 0.441 0.559
C81.2 Mixed cellularity
0.552 0.448 0.000
C81.0 Lymphocytic predominance
0.547 0.452 0.000
D52.9 Folate deficiency anaemia, unspecified
0.000 0.453 0.547
D83 Common variable immunodeficiency
0.000 0.456 0.544
E22.1 Hyperprolactinaemia
0.000 0.457 0.543
D80 Immunodeficiency with predominantly antibody defects
0.000 0.465 0.535
E14.3 With ophthalmic complications
0.000 0.466 0.534
C95.0 Acute leukaemia of unspecified cell type
0.533 0.467 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.468 0.532
E22.0 Acromegaly and pituitary gigantism
0.000 0.470 0.530
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.470 0.529
E22.8 Other hyperfunction of pituitary gland
0.000 0.470 0.529
C43-C44 Melanoma and other malignant neoplasms of skin
0.527 0.473 0.000
C81.7 Other Hodgkin's disease
0.520 0.479 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.520 0.479 0.000
C81.3 Lymphocytic depletion
0.520 0.479 0.000
E29 Testicular dysfunction
0.000 0.488 0.512
E13.9 Without complications
0.000 0.488 0.512
E65-E68 Obesity and other hyperalimentation
0.000 0.489 0.511
C84.0 Mycosis fungoides
0.509 0.491 0.000
D84 Other immunodeficiencies
0.001 0.497 0.503
E14.8 With unspecified complications
0.000 0.497 0.503
E14.7 With multiple complications
0.000 0.497 0.503
E14.2 Withrenal complications
0.000 0.497 0.503
E14.1 With ketoacidosis
0.000 0.497 0.503
E14.0 With coma
0.000 0.497 0.503
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.500 0.500 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.500 0.500 0.000
C86.4 Blastic NK-cell lymphoma
0.500 0.500 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.500 0.500 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.500 0.500 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.500 0.500 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.500 0.500 0.000
C93.9 Monocytic leukaemia, unspecified
0.500 0.500 0.000
C93.7 Other monocytic leukaemia
0.500 0.500 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.500 0.500 0.000
C93.2 Subacute monocytic leukaemia
0.500 0.500 0.000
C93.1 Chronic monocytic leukaemia
0.500 0.500 0.000
C93.0 Acute monocytic leukaemia
0.500 0.500 0.000
C94.7 Other specified leukaemias
0.500 0.500 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.500 0.500 0.000
C94.5 Acute myelofibrosis
0.500 0.500 0.000
C94.4 Acute panmyelosis
0.500 0.500 0.000
C94.3 Mast cell leukaemia
0.500 0.500 0.000
C94.2 Acute megakaryoblastic leukaemia
0.500 0.500 0.000
C94.1 Chronic erythraemia
0.500 0.500 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.500 0.500 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.500 0.500 0.000
C96.8 Histiocytic sarcoma
0.500 0.500 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.500 0.500 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.500 0.500 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.500 0.500 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.500 0.500 0.000
C96.3 True histiocytic lymphoma
0.500 0.500 0.000
C96.2 Malignant mast cell tumour
0.500 0.500 0.000
C96.1 Malignant histiocytosis
0.500 0.500 0.000
C96.0 Letterer-Siwe disease
0.500 0.500 0.000
C84.4 Peripheral T-cell lymphoma
0.499 0.501 0.000
E24.8 Other Cushing's syndrome
0.000 0.502 0.497
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.502 0.497
E24.3 Ectopic ACTH syndrome
0.000 0.502 0.497
E24.2 Drug-induced Cushing's syndrome
0.000 0.502 0.497
E24.1 Nelson's syndrome
0.000 0.502 0.497
E24.0 Pituitary-dependent Cushing's disease
0.000 0.502 0.497
E00-E07 Disorders of thyroid gland
0.000 0.504 0.496
C84.9 Mature T/NK-cell lymphoma, unspecified
0.496 0.504 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.496 0.504 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.496 0.504 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.496 0.504 0.000
C84.3 Lymphoepithelioid lymphoma
0.496 0.504 0.000
C84.2 T-zone lymphoma
0.496 0.504 0.000
C84.1 Sezary's diease
0.496 0.504 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.504 0.496
E21.4 Other specified disorders of parathyroid gland
0.000 0.504 0.496
E21.2 Other hyperparathyroidism
0.000 0.504 0.496
C95.7 Other leukaemia of unspecified cell type
0.492 0.508 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.492 0.508 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.492 0.508 0.000
D52.8 Other folate deficiency anaemias
0.000 0.509 0.491
D52.1 Drug-induced folate deficiency anaemia
0.000 0.509 0.491
D52.0 Dietary folate deficiency anaemia
0.000 0.509 0.491
E13.8 With unspecified complications
0.000 0.510 0.489
E13.7 With multiple complications
0.000 0.510 0.489
E13.6 With other specified complications
0.000 0.510 0.489
E13.5 With peripheral circulatory complications
0.000 0.510 0.489
E13.4 With neurological complications
0.000 0.510 0.489
E13.3 With ophthalmic complications
0.000 0.510 0.489
E13.2 With renal complications
0.000 0.510 0.489
E13.1 With ketoacidosis
0.000 0.510 0.489
E13.0 With coma
0.000 0.510 0.489
E50-E64 Other nutritional deficiencies
0.000 0.513 0.487
E14.6 With other specified complications
0.000 0.513 0.487
E14.5 With peripheral circulatory complications
0.000 0.518 0.482
E12.9 Without complications
0.000 0.526 0.474
E12.8 With unspecified complications
0.000 0.526 0.474
E12.7 With multiple complications
0.000 0.526 0.474
E12.6 With other specified complications
0.000 0.526 0.474
E12.5 With peripheral circulatory complications
0.000 0.526 0.474
E12.4 With neurological complications
0.000 0.526 0.474
E12.3 With ophthalmic complications
0.000 0.526 0.474
E12.2 With renal complications
0.000 0.526 0.474
E12.1 With ketoacidosis
0.000 0.526 0.474
E12.0 With coma
0.000 0.526 0.474
C84.5 Other and unspecified T-cell lymphomas
0.473 0.526 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.472 0.527 0.000
E34.0 Carcinoid syndrome
0.000 0.531 0.469
D59 Acquired haemolytic anaemia
0.000 0.531 0.469
E21.3 Hyperparathyroidism, unspecified
0.000 0.548 0.452
E14.4 With neurological complications
0.000 0.551 0.449
E03 Other hypothyroidism
0.000 0.552 0.448
E20.9 Hypoparathyroidism, unspecified
0.000 0.552 0.447
C88.9 Malignant immunoproliferative disease, unspecified
0.447 0.553 0.000
C88.7 Other malignant immunoproliferative diseases
0.447 0.553 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.447 0.553 0.000
C88.3 Immunoproliferative small intestinal disease
0.447 0.553 0.000
C88.2 Gamma heavy chain disease
0.447 0.553 0.000
C88.1 Alpha heavy chain disease
0.447 0.553 0.000
C91 Lymphoid leukaemia
0.445 0.553 0.001
D81.9 Combined immunodeficiency, unspecified
0.000 0.554 0.446
D81.8 Other combined immunodeficiencies
0.000 0.554 0.446
D81.7 Major histocompatibility complex class II deficiency
0.000 0.554 0.446
D81.6 Major histocompatibility complex class I deficiency
0.000 0.554 0.446
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.554 0.446
D81.4 Nezelof's syndrome
0.000 0.554 0.446
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.554 0.446
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.554 0.446
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.554 0.446
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.554 0.446
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.554 0.446
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.554 0.446
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.554 0.446
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.554 0.446
D82.2 Immunodeficiency with short-limbed stature
0.000 0.554 0.446
D82.1 Di George's syndrome
0.000 0.554 0.446
D82.0 Wiskott-Aldrich syndrome
0.000 0.554 0.446
C90.3 Solitary plasmacytoma
0.445 0.555 0.000
C90.1 Plasma cell leukaemia
0.445 0.555 0.000
E20.8 Other hypoparathyroidism
0.000 0.558 0.442
E20.1 Pseudohypoparathyroidism
0.000 0.558 0.442
E20.0 Idiopathic hypoparathyroidism
0.000 0.558 0.442
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.562 0.438
E25.9 Adrenogenital disorder, unspecified
0.000 0.562 0.438
E25.8 Other adrenogenital disorders
0.000 0.562 0.438
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.562 0.438
E30.9 Disorder of puberty, unspecified
0.000 0.562 0.438
E30.8 Other disorders of puberty
0.000 0.562 0.438
E30.1 Precocious puberty
0.000 0.562 0.438
E30.0 Delayed puberty
0.000 0.562 0.438
E31.9 Polyglandular dysfunction, unspecified
0.000 0.562 0.438
E31.8 Other polyglandular dysfunction
0.000 0.562 0.438
E31.1 Polyglandular hyperfunction
0.000 0.562 0.438
E31.0 Autoimmune polyglandular failure
0.000 0.562 0.438
E32.9 Disease of thymus, unspecified
0.000 0.562 0.438
E32.8 Other diseases of thymus
0.000 0.562 0.438
E32.1 Abscess of thymus
0.000 0.562 0.438
E32.0 Persistent hyperplasia of thymus
0.000 0.562 0.438
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.562 0.438
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.562 0.438
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.562 0.438
D53.8 Other specified nutritional anaemias
0.000 0.563 0.437
D53.2 Scorbutic anaemia
0.000 0.563 0.437
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.563 0.437
D53.0 Protein deficiency anaemia
0.000 0.563 0.437
C90.0 Multiple myeloma
0.435 0.565 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.567 0.433
C83.0 Small cell (diffuse)
0.432 0.568 0.001
C95.9 Leukaemia, unspecified
0.427 0.573 0.000
C92 Myeloid leukaemia
0.425 0.575 0.000
D53.9 Nutritional anaemia, unspecified
0.000 0.584 0.416
E03.9 Hypothyroidism, unspecified
0.000 0.584 0.416
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.586 0.413
E45 Retarded development following protein-energy malnutrition
0.000 0.586 0.413
E43 Unspecified severe protein-energy malnutrition
0.000 0.586 0.413
E42 Marasmic kwashiorkor
0.000 0.586 0.413
E41 Nutritional marasmus
0.000 0.586 0.413
E40 Kwashiorkor
0.000 0.586 0.413
E53 Deficiency of other B group vitamins
0.000 0.588 0.412
D57 Sickle-cell disorders
0.000 0.592 0.407
D55 Anaemia due to enzyme disorders
0.000 0.592 0.407
E34.5 Androgen resistance syndrome
0.000 0.597 0.403
E34.4 Constitutional tall stature
0.000 0.597 0.403
E34.3 Short stature, not elsewhere classified
0.000 0.597 0.403
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.597 0.403
E34.1 Other hypersecretion of intestinal hormones
0.000 0.597 0.403
D59.1 Other autoimmune haemolytic anaemias
0.000 0.601 0.399
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.603 0.397
E28 Ovarian dysfunction
0.000 0.606 0.394
D83.8 Other common variable immunodeficiencies
0.000 0.610 0.390
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.610 0.390
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.610 0.390
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.610 0.390
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.616 0.383
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.616 0.383
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.616 0.383
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.616 0.383
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.616 0.383
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.616 0.383
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.616 0.383
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.616 0.383
C90.2 Plasmacytoma, extramedullary
0.383 0.617 0.000
C91.5 Adult T-cell leukaemia
0.381 0.618 0.001
E26 Hyperaldosteronism
0.001 0.624 0.375
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.625 0.375
C88.0 Waldenstrom's macroglobulinaemia
0.374 0.626 0.000
J45 Asthma
0.000 0.628 0.372
E29.9 Testicular dysfunction, unspecified
0.000 0.632 0.367
E29.8 Other testicular dysfunction
0.000 0.632 0.367
E29.0 Testicular hyperfunction
0.000 0.632 0.367
E67 Other hyperalimentation
0.000 0.634 0.366
E68 Sequelae of hyperalimentation
0.000 0.634 0.366
D84.8 Other specified immunodeficiencies
0.001 0.639 0.361
D84.1 Defects in the complement system
0.001 0.639 0.361
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.001 0.639 0.361
E53.8 Deficiency of other specified B group vitamins
0.000 0.640 0.360
E34.8 Other specified endocrine disorders
0.000 0.641 0.359
E27.9 Disorder of adrenal gland, unspecified
0.001 0.642 0.357
C91.9 Lymphoid leukaemia, unspecified
0.356 0.643 0.001
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.643 0.357
E66 Obesity
0.000 0.643 0.357
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.644 0.356
E00 Congenital iodine-deficiency syndrome
0.000 0.644 0.356
Chapter II Neoplasms
0.352 0.648 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.649 0.351
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.650 0.349
E63 Other nutritional deficiencies
0.000 0.650 0.349
E56 Other vitamin deficiencies
0.000 0.650 0.349
E50 Vitamin A deficiency
0.000 0.650 0.349
E60 Dietary zinc deficiency
0.000 0.650 0.349
E59 Dietary selenium deficiency
0.000 0.650 0.349
E54 Ascorbic acid deficiency
0.000 0.650 0.349
E52 Niacin deficiency [pellagra]
0.000 0.650 0.349
D56 Thalassaemia
0.000 0.651 0.349
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.349 0.651 0.000
C73 Malignant neoplasm of thyroid gland
0.346 0.654 0.000
C81.9 Hodgkin's disease, unspecified
0.343 0.657 0.000
D59.8 Other acquired haemolytic anaemias
0.000 0.664 0.336
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.664 0.336
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.664 0.336
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.664 0.336
D59.3 Haemolytic-uraemic syndrome
0.000 0.664 0.336
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.664 0.336
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.664 0.336
E06 Thyroiditis
0.000 0.665 0.335
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.666 0.334
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.667 0.332
D58 Other hereditary haemolytic anaemias
0.000 0.668 0.332
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.669 0.331
E51 Thiamine deficiency
0.000 0.676 0.323
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.676 0.324
E58 Dietary calcium deficiency
0.000 0.678 0.322
E03.5 Myxoedema coma
0.000 0.679 0.321
E03.4 Atrophy of thyroid (acquired)
0.000 0.679 0.321
E03.3 Postinfectious hypothyroidism
0.000 0.679 0.321
E03.1 Congenital hypothyroidism without goitre
0.000 0.679 0.321
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.679 0.321
C91.8 Mature B-cell leukaemia Burkitt-type
0.319 0.680 0.001
C91.7 Other lymphoid leukaemia
0.319 0.680 0.001
C91.6 Prolymphocytic leukaemia of T-cell type
0.319 0.680 0.001
C91.3 Prolymphocytic leukaemia
0.319 0.680 0.001
C91.2 Subacute lymphocytic leukaemia
0.319 0.680 0.001
D83.9 Common variable immunodeficiency, unspecified
0.001 0.687 0.313
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.689 0.311
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.689 0.311
D89.3 Immune reconstitution syndrome
0.000 0.689 0.311
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.689 0.311
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.691 0.308
C92.9 Myeloid leukaemia, unspecified
0.304 0.695 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.304 0.695 0.000
C92.7 Other myeloid leukaemia
0.304 0.695 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.304 0.695 0.000
C92.5 Acute myelomonocytic leukaemia
0.304 0.695 0.000
C92.4 Acute promyelocytic leukaemia
0.304 0.695 0.000
C92.3 Myeloid sarcoma
0.304 0.695 0.000
C92.2 Subacute myeloid leukaemia
0.304 0.695 0.000
E03.8 Other specified hypothyroidism
0.000 0.698 0.302
E11 Non-insulin-dependent diabetes mellitus
0.000 0.700 0.300
E44.1 Mild protein-energy malnutrition
0.000 0.703 0.296
E44.0 Moderate protein-energy malnutrition
0.000 0.703 0.296
E53.1 Pyridoxine deficiency
0.000 0.705 0.295
E53.0 Riboflavin deficiency
0.000 0.705 0.295
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.707 0.292
D55.8 Other anaemias due to enzyme disorders
0.000 0.707 0.292
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.707 0.292
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.707 0.292
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.707 0.292
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.707 0.292
D57.8 Other sickle-cell disorders
0.000 0.707 0.292
D57.3 Sickle-cell trait
0.000 0.707 0.292
D57.2 Double heterozygous sickling disorders
0.000 0.707 0.292
D57.1 Sickle-cell anaemia without crisis
0.000 0.707 0.292
D57.0 Sickle-cell anaemia with crisis
0.000 0.707 0.292
E53.9 Vitamin B deficiency, unspecified
0.000 0.709 0.291
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.290 0.710 0.000
M06.9 Rheumatoid arthritis, unspecified
0.288 0.712 0.000
E34.9 Endocrine disorder, unspecified
0.001 0.713 0.286
E05.8 Other thyrotoxicosis
0.000 0.715 0.285
E05.5 Thyroid crisis or storm
0.000 0.715 0.285
E05.4 Thyrotoxicosis factitia
0.000 0.715 0.285
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.715 0.285
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.715 0.285
E28.9 Ovarian dysfunction, unspecified
0.000 0.717 0.282
E28.8 Other ovarian dysfunction
0.000 0.717 0.282
E28.1 Androgen excess
0.000 0.717 0.282
E28.0 Oestrogen excess
0.000 0.717 0.282
M06 Other rheumatoid arthritis
0.281 0.719 0.000
M06.0 Seronegative rheumatoid arthritis
0.281 0.719 0.000
E61 Deficiency of other nutrient elements
0.000 0.722 0.278
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.278 0.722 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.276 0.724 0.000
E66.8 Other obesity
0.000 0.724 0.276
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.275 0.725 0.000
C74 Malignant neoplasm of adrenal gland
0.274 0.725 0.000
D89.1 Cryoglobulinaemia
0.000 0.728 0.271
E23 Hypofunction and other disorders of pituitary gland
0.001 0.729 0.269
E26.8 Other hyperaldosteronism
0.001 0.730 0.269
E26.1 Secondary hyperaldosteronism
0.001 0.730 0.269
E29.1 Testicular hypofunction
0.000 0.730 0.269
E11.1 With ketoacidosis
0.000 0.732 0.268
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.733 0.267
J45.8 Mixed asthma
0.000 0.733 0.267
J45.1 Nonallergic asthma
0.000 0.733 0.267
C02 Malignant neoplasm of other and unspecified parts of tongue
0.265 0.735 0.000
E67.8 Other specified hyperalimentation
0.000 0.737 0.263
E67.3 Hypervitaminosis D
0.000 0.737 0.263
E67.2 Megavitamin-B6 syndrome
0.000 0.737 0.263
E67.1 Hypercarotenaemia
0.000 0.737 0.263
E67.0 Hypervitaminosis A
0.000 0.737 0.263
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.739 0.261
M45.X9 Ankylosing spondylitis (Site unspecified)
0.259 0.741 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.257 0.743 0.000
C91.0 Acute lymphoblastic leukaemia
0.255 0.743 0.001
E66.1 Drug-induced obesity
0.000 0.744 0.256
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.745 0.255
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.745 0.255
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.745 0.255
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.745 0.255
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.745 0.255
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.745 0.255
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.745 0.255
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.745 0.255
K50.0 Crohn's disease of small intestine
0.254 0.745 0.001
E65 Localised adiposity
0.000 0.745 0.254
E07 Other disorders of thyroid
0.000 0.747 0.253
D50.8 Other iron deficiency anaemias
0.000 0.748 0.252
E50.9 Vitamin A deficiency, unspecified
0.000 0.749 0.250
E50.8 Other manifestations of vitamin A deficiency
0.000 0.749 0.250
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.749 0.250
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.749 0.250

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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