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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28367592
log Bayes Factor = 12.7845
Chromosome 6   position 31,253,716  (GRCh37) Explore rs28367592 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
E10-E14 Diabetes mellitus
0.000 0.003 0.997
E10 Insulin-dependent diabetes mellitus
0.000 0.006 0.994
M06 Other rheumatoid arthritis
0.000 0.008 0.992
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.008 0.992
# Top node
0.000 0.008 0.992
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.009 0.991
D50-D53 Nutritional anaemias
0.000 0.012 0.988
D50 Iron deficiency anaemia
0.000 0.015 0.985
E10.9 Without complications
0.000 0.017 0.983
D50.9 Iron deficiency anaemia, unspecified
0.000 0.017 0.983
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.020 0.980
M05-M14 Inflammatory polyarthropathies
0.000 0.024 0.976
D60-D64 Aplastic and other anaemias
0.000 0.030 0.970
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.040 0.960
L08 Other local infections of skin and subcutaneous tissue
0.000 0.049 0.951
D64 Other anaemias
0.000 0.049 0.951
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.056 0.944
D64.9 Anaemia, unspecified
0.000 0.063 0.937
Chapter I Certain infectious and parasitic diseases
0.000 0.063 0.937
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.067 0.933
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.084 0.916
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.085 0.915
E10.3 With ophthalmic complications
0.000 0.090 0.910
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.098 0.902
M06.0 Seronegative rheumatoid arthritis
0.000 0.098 0.902
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.102 0.898
B35-B49 Mycoses
0.000 0.104 0.896
L57.0 Actinic keratosis
0.000 0.113 0.887
M07 Psoriatic and enteropathic arthropathies
0.000 0.113 0.887
B37 Candidiasis
0.000 0.120 0.880
E14 Unspecified diabetes mellitus
0.000 0.120 0.880
E70-E90 Metabolic disorders
0.000 0.127 0.873
N48 Other disorders of penis
0.873 0.127 0.000
N40-N51 Diseases of male genital organs
0.870 0.130 0.000
B25-B34 Other viral diseases
0.000 0.131 0.869
N43 Hydrocele and spermatocele
0.866 0.134 0.000
N48.6 Balanitis xerotica obliterans
0.865 0.135 0.000
N43.3 Hydrocele, unspecified
0.865 0.135 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.137 0.863
Chapter VI Diseases of the nervous system
0.000 0.142 0.858
B37.8 Candidiasis of other sites
0.000 0.146 0.854
M05 Seropositive rheumatoid arthritis
0.000 0.152 0.848
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.155 0.845
L40.0 Psoriasis vulgaris
0.000 0.157 0.843
E06 Thyroiditis
0.000 0.162 0.838
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.167 0.833
E40-E46 Malnutrition
0.000 0.176 0.824
M07.3 Other psoriatic arthropathies
0.000 0.177 0.823
E89.0 Postprocedural hypothyroidism
0.000 0.178 0.822
B34 Viral infection of unspecified site
0.000 0.179 0.821
N41 Inflammatory diseases of prostate
0.819 0.181 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.181 0.819
B37.0 Candidal stomatitis
0.000 0.185 0.815
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.187 0.813
G35 Multiple sclerosis
0.000 0.188 0.812
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.188 0.812
N48.0 Leukoplakia of penis
0.810 0.190 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.195 0.805
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.203 0.797
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.209 0.791
E14.9 Without complications
0.000 0.209 0.791
N50 Other disorders of male genital organs
0.790 0.210 0.000
E10.5 With peripheral circulatory complications
0.000 0.214 0.786
E86 Volume depletion
0.000 0.214 0.786
B34.9 Viral infection, unspecified
0.000 0.214 0.786
G30-G32 Other degenerative diseases of the nervous system
0.000 0.217 0.783
D61 Other aplastic anaemias
0.000 0.220 0.780
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.222 0.778
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.222 0.778
E50-E64 Other nutritional deficiencies
0.000 0.224 0.776
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.232 0.768
N48.8 Other specified disorders of penis
0.765 0.235 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.242 0.758
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.243 0.757
N50.8 Other specified disorders of male genital organs
0.757 0.243 0.000
A30-A49 Other bacterial diseases
0.000 0.249 0.751
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.250 0.750
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.253 0.747
D51 Vitamin B12 deficiency anaemia
0.000 0.254 0.745
N41.9 Inflammatory disease of prostate, unspecified
0.745 0.255 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.255 0.744
E10.4 With neurological complications
0.000 0.256 0.744
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.260 0.740
E03.8 Other specified hypothyroidism
0.000 0.270 0.729
N48.2 Other inflammatory disorders of penis
0.723 0.277 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.277 0.723
E06.3 Autoimmune thyroiditis
0.000 0.278 0.722
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.282 0.718
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M11 Other crystal arthropathies
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
L10-L14 Bullous disorders
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.286 0.713
E10.8 With unspecified complications
0.000 0.287 0.713
E10.7 With multiple complications
0.000 0.287 0.713
E10.6 With other specified complications
0.000 0.287 0.713
E10.2 With renal complications
0.000 0.287 0.713
E10.0 With coma
0.000 0.287 0.713
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.287 0.713
M06.8 Other specified rheumatoid arthritis
0.000 0.289 0.711
M06.2 Rheumatoid bursitis
0.000 0.289 0.711
M06.1 Adult-onset Still's disease
0.000 0.289 0.711
D55-D59 Haemolytic anaemias
0.000 0.289 0.711
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.289 0.711
D52 Folate deficiency anaemia
0.000 0.290 0.710
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.291 0.709
D53 Other nutritional anaemias
0.000 0.291 0.708
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.292 0.708
M06.4 Inflammatory polyarthropathy
0.000 0.293 0.707
D50.1 Sideropenic dysphagia
0.000 0.293 0.706
E10.1 With ketoacidosis
0.000 0.294 0.706
L04 Acute lymphadenitis
0.000 0.297 0.703
L01 Impetigo
0.000 0.297 0.703
L00 Staphylococcal scalded skin syndrome
0.000 0.297 0.703
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.297 0.702
B35 Dermatophytosis
0.000 0.298 0.702
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.299 0.701
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.299 0.701
M12 Other specific arthropathies
0.000 0.300 0.699
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.300 0.699
M08 Juvenile arthritis
0.000 0.300 0.699
N42 Other disorders of prostate
0.699 0.301 0.000
M00-M03 Infectious arthropathies
0.000 0.301 0.699
H43-H45 Disorders of vitreous body and globe
0.000 0.301 0.699
M14 Arthropathies in other diseases classified elsewhere
0.000 0.301 0.698
E46 Unspecified protein-energy malnutrition
0.000 0.302 0.698
E13 Other specified diabetes mellitus
0.000 0.302 0.698
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.304 0.695
M06.3 Rheumatoid nodule
0.000 0.310 0.690
M45-M49 Spondylopathies
0.000 0.311 0.689
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.311 0.688
L58 Radiodermatitis
0.000 0.311 0.688
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.311 0.688
L55 Sunburn
0.000 0.311 0.688
L20-L30 Dermatitis and eczema
0.000 0.314 0.686
E04 Other non-toxic goitre
0.000 0.315 0.685
G70-G73 Diseases of myoneural junction and muscle
0.000 0.317 0.682
L08.1 Erythrasma
0.000 0.318 0.682
L08.0 Pyoderma
0.000 0.318 0.682
D64.8 Other specified anaemias
0.000 0.318 0.682
D64.4 Congenital dyserythropoietic anaemia
0.000 0.318 0.682
D64.3 Other sideroblastic anaemias
0.000 0.318 0.682
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.318 0.682
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.318 0.682
D64.0 Hereditary sideroblastic anaemia
0.000 0.318 0.682
N48.9 Disorder of penis, unspecified
0.678 0.321 0.000
A00-A09 Intestinal infectious diseases
0.000 0.324 0.676
B99-B99 Other infectious diseases
0.000 0.325 0.675
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.328 0.672
B50-B64 Protozoal diseases
0.000 0.328 0.672
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.328 0.672
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.328 0.672
A75-A79 Rickettsioses
0.000 0.328 0.672
A70-A74 Other diseases caused by chlamydiae
0.000 0.328 0.672
A65-A69 Other spirochaetal diseases
0.000 0.328 0.672
A20-A28 Certain zoonotic bacterial diseases
0.000 0.328 0.672
A15-A19 Tuberculosis
0.000 0.328 0.672
D80-D89 Certain disorders involving the immune mechanism
0.000 0.330 0.670
N41.0 Acute prostatitis
0.670 0.330 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.331 0.669
L57.5 Actinic granuloma
0.000 0.331 0.669
L57.4 Cutis laxa senilis
0.000 0.331 0.669
L57.3 Poikiloderma of Civatte
0.000 0.331 0.669
L57.2 Cutis rhomboidalis nuchae
0.000 0.331 0.669
L57.1 Actinic reticuloid
0.000 0.331 0.669
D72 Other disorders of white blood cells
0.000 0.332 0.668
M65-M68 Disorders of synovium and tendon
0.000 0.333 0.667
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.335 0.665
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.339 0.661
B65-B83 Helminthiases
0.000 0.340 0.660
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.342 0.658
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.343 0.657
E88 Other metabolic disorders
0.000 0.344 0.656
M45 Ankylosing spondylitis
0.000 0.344 0.656
H43 Disorders of vitreous body
0.000 0.345 0.655
E11 Non-insulin-dependent diabetes mellitus
0.000 0.345 0.655
L81 Other disorders of pigmentation
0.000 0.345 0.655
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.346 0.654
E89.2 Postprocedural hypoparathyroidism
0.000 0.350 0.650
E07 Other disorders of thyroid
0.000 0.350 0.649
N50.9 Disorder of male genital organs, unspecified
0.649 0.350 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.353 0.646
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.353 0.646
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.353 0.646
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.353 0.646
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.353 0.646
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.353 0.646
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.353 0.646
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.353 0.646
N41.1 Chronic prostatitis
0.645 0.355 0.000
D61.9 Aplastic anaemia, unspecified
0.000 0.355 0.644
D50.8 Other iron deficiency anaemias
0.000 0.356 0.644
B37.3 Candidiasis of vulva and vagina
0.000 0.356 0.644
B48 Other mycoses, not elsewhere classified
0.000 0.357 0.643
B47 Mycetoma
0.000 0.357 0.643
B46 Zygomycosis
0.000 0.357 0.643
B45 Cryptococcosis
0.000 0.357 0.643
B43 Chromomycosis and phaeomycotic abscess
0.000 0.357 0.643
B42 Sporotrichosis
0.000 0.357 0.643
B41 Paracoccidioidomycosis
0.000 0.357 0.643
B40 Blastomycosis
0.000 0.357 0.643
B39 Histoplasmosis
0.000 0.357 0.643
B38 Coccidioidomycosis
0.000 0.357 0.643
B36 Other superficial mycoses
0.000 0.357 0.643
E14.3 With ophthalmic complications
0.000 0.357 0.643
H40-H42 Glaucoma
0.000 0.358 0.642
M07.6 Other enteropathic arthropathies
0.000 0.364 0.636
M07.5 Arthropathy in ulcerative colitis
0.000 0.364 0.636
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.364 0.636
M07.2 Psoriatic spondylitis
0.000 0.364 0.636
M07.1 Arthritis mutilans
0.000 0.364 0.636
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.364 0.636
G30 Alzheimer's disease
0.000 0.365 0.635
D62 Acute posthaemorrhagic anaemia
0.000 0.365 0.634
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.367 0.633
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.367 0.633
G37 Other demyelinating diseases of central nervous system
0.000 0.368 0.632
L91 Hypertrophic disorders of skin
0.000 0.368 0.632
B15-B19 Viral hepatitis
0.000 0.369 0.631
B37.7 Candidal septicaemia
0.000 0.369 0.631
B37.6 Candidal endocarditis
0.000 0.369 0.631
B37.5 Candidal meningitis
0.000 0.369 0.631
B37.4 Candidiasis of other urogenital sites
0.000 0.369 0.631
B37.2 Candidiasis of skin and nail
0.000 0.369 0.631
B37.1 Pulmonary candidiasis
0.000 0.369 0.631
E14.8 With unspecified complications
0.000 0.369 0.631
E14.7 With multiple complications
0.000 0.369 0.631
E14.6 With other specified complications
0.000 0.369 0.631
E14.5 With peripheral circulatory complications
0.000 0.369 0.631
E14.4 With neurological complications
0.000 0.369 0.631
E14.2 Withrenal complications
0.000 0.369 0.631
E14.1 With ketoacidosis
0.000 0.369 0.631
E14.0 With coma
0.000 0.369 0.631
L05 Pilonidal cyst
0.000 0.370 0.630
H53-H54 Visual disturbances and blindness
0.000 0.371 0.629
N42.8 Other specified disorders of prostate
0.627 0.373 0.000
E84 Cystic fibrosis
0.000 0.374 0.626
E79 Disorders of purine and pyrimidine metabolism
0.000 0.374 0.626
E77 Disorders of glycoprotein metabolism
0.000 0.374 0.626
E76 Disorders of glycosaminoglycan metabolism
0.000 0.374 0.626
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.374 0.626
E73 Lactose intolerance
0.000 0.374 0.626
E72 Other disorders of amino-acid metabolism
0.000 0.374 0.626
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.374 0.626
E70 Disorders of aromatic amino-acid metabolism
0.000 0.374 0.626
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.374 0.626
N48.5 Ulcer of penis
0.626 0.374 0.000
N48.3 Priapism
0.626 0.374 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.626 0.374 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.624 0.376 0.000
N46 Male infertility
0.624 0.376 0.000
N44 Torsion of testis
0.624 0.376 0.000
B33 Other viral diseases, not elsewhere classified
0.000 0.377 0.623
B30 Viral conjunctivitis
0.000 0.377 0.623
B27 Infectious mononucleosis
0.000 0.377 0.623
B26 Mumps
0.000 0.377 0.623
B25 Cytomegaloviral disease
0.000 0.377 0.623
N43.4 Spermatocele
0.621 0.379 0.000
N43.2 Other hydrocele
0.621 0.379 0.000
N43.1 Infected hydrocele
0.621 0.379 0.000
N43.0 Encysted hydrocele
0.621 0.379 0.000
M80-M85 Disorders of bone density and structure
0.000 0.380 0.620
M60-M63 Disorders of muscles
0.000 0.380 0.619
E05.5 Thyroid crisis or storm
0.000 0.381 0.618
E05.4 Thyrotoxicosis factitia
0.000 0.381 0.618
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.381 0.618
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.381 0.618
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.381 0.618
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.382 0.618
D73 Diseases of spleen
0.000 0.384 0.616
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.384 0.616
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.385 0.615
D75 Other diseases of blood and blood-forming organs
0.000 0.385 0.615
N45 Orchitis and epididymitis
0.611 0.389 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.390 0.610
A80-A89 Viral infections of the central nervous system
0.000 0.392 0.608
M05.8 Other seropositive rheumatoid arthritis
0.000 0.392 0.608
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.392 0.608
M05.2 Rheumatoid vasculitis
0.000 0.392 0.608
M05.1 Rheumatoid lung disease
0.000 0.392 0.608
M05.0 Felty's syndrome
0.000 0.392 0.608
E53 Deficiency of other B group vitamins
0.000 0.392 0.608
Chapter XXII Codes for special purposes
0.000 0.393 0.607
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.394 0.606
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.394 0.606
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.394 0.606
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.394 0.606
E89.5 Postprocedural testicular hypofunction
0.000 0.394 0.606
E89.4 Postprocedural ovarian failure
0.000 0.394 0.606
E89.1 Postprocedural hypoinsulinaemia
0.000 0.394 0.606
G31.8 Other specified degenerative diseases of nervous system
0.000 0.395 0.605
E06.9 Thyroiditis, unspecified
0.000 0.399 0.601
E06.5 Other chronic thyroiditis
0.000 0.399 0.601
E06.4 Drug-induced thyroiditis
0.000 0.399 0.601
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.399 0.601
E06.1 Subacute thyroiditis
0.000 0.399 0.601
E06.0 Acute thyroiditis
0.000 0.399 0.601
E74 Other disorders of carbohydrate metabolism
0.000 0.400 0.600
L42 Pityriasis rosea
0.000 0.401 0.599
L43 Lichen planus
0.000 0.402 0.598
G36 Other acute disseminated demyelination
0.000 0.403 0.597
A41 Other septicaemia
0.000 0.404 0.596
L85 Other epidermal thickening
0.000 0.404 0.596
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.404 0.595
L81.4 Other melanin hyperpigmentation
0.000 0.405 0.595
G70 Myasthenia gravis and other myoneural disorders
0.000 0.406 0.594
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.409 0.591
E45 Retarded development following protein-energy malnutrition
0.000 0.409 0.591
E43 Unspecified severe protein-energy malnutrition
0.000 0.409 0.591
E42 Marasmic kwashiorkor
0.000 0.409 0.591
E41 Nutritional marasmus
0.000 0.409 0.591
E40 Kwashiorkor
0.000 0.409 0.591
M07.38 Other psoriatic arthropathies (Other)
0.000 0.410 0.590
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.410 0.590
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.410 0.590
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.410 0.590
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.410 0.590
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.410 0.590
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.410 0.590
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.410 0.590
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.410 0.590
A46 Erysipelas
0.000 0.410 0.590
E89.3 Postprocedural hypopituitarism
0.000 0.411 0.589
B34.8 Other viral infections of unspecified site
0.000 0.412 0.588
B34.4 Papovirus infection, unspecified
0.000 0.412 0.588
B34.3 Parvovirus infection, unspecified
0.000 0.412 0.588
B34.2 Coronavirus infection, unspecified
0.000 0.412 0.588
B34.1 Enterovirus infection, unspecified
0.000 0.412 0.588
B34.0 Adenovirus infection, unspecified
0.000 0.412 0.588
D72.8 Other specified disorders of white blood cells
0.000 0.412 0.588
N41.8 Other inflammatory diseases of prostate
0.587 0.412 0.000
N41.3 Prostatocystitis
0.587 0.412 0.000
N41.2 Abscess of prostate
0.587 0.412 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.414 0.586
H43.3 Other vitreous opacities
0.000 0.415 0.585
M10 Gout
0.000 0.417 0.583
G62 Other polyneuropathies
0.000 0.417 0.583
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.419 0.581
E80.4 Gilbert's syndrome
0.000 0.420 0.580
E04.2 Non-toxic multinodular goitre
0.000 0.421 0.579
L83 Acanthosis nigricans
0.000 0.422 0.577
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.576 0.424 0.000
M91-M94 Chondropathies
0.000 0.428 0.572
L89 Decubitus ulcer
0.000 0.430 0.570
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.431 0.569
L50-L54 Urticaria and erythema
0.000 0.431 0.569
E55 Vitamin D deficiency
0.000 0.432 0.568
D74 Methaemoglobinaemia
0.000 0.433 0.567
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.433 0.567
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.433 0.567
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.435 0.564
B35.3 Tinea pedis
0.000 0.437 0.563
M65 Synovitis and tenosynovitis
0.000 0.438 0.562
B49 Unspecified mycosis
0.000 0.439 0.561
N48.4 Impotence of organic origin
0.561 0.439 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.439 0.561
D61.8 Other specified aplastic anaemias
0.000 0.440 0.560
D61.3 Idiopathic aplastic anaemia
0.000 0.440 0.560
D61.2 Aplastic anaemia due to other external agents
0.000 0.440 0.560
D61.1 Drug-induced aplastic anaemia
0.000 0.440 0.560
D61.0 Constitutional aplastic anaemia
0.000 0.440 0.560
L29 Pruritus
0.000 0.441 0.559
H30-H36 Disorders of choroid and retina
0.000 0.441 0.559
H40 Glaucoma
0.000 0.441 0.559
H10-H13 Disorders of conjunctiva
0.000 0.443 0.557
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.443 0.556
E63 Other nutritional deficiencies
0.000 0.443 0.556
E56 Other vitamin deficiencies
0.000 0.443 0.556
E51 Thiamine deficiency
0.000 0.443 0.556
E50 Vitamin A deficiency
0.000 0.443 0.556
E60 Dietary zinc deficiency
0.000 0.443 0.556
E59 Dietary selenium deficiency
0.000 0.443 0.556
E58 Dietary calcium deficiency
0.000 0.443 0.556
E54 Ascorbic acid deficiency
0.000 0.443 0.556
E52 Niacin deficiency [pellagra]
0.000 0.443 0.556
E61 Deficiency of other nutrient elements
0.000 0.444 0.555
M80 Osteoporosis with pathological fracture
0.000 0.446 0.554
H43.8 Other disorders of vitreous body
0.000 0.449 0.551
L91.8 Other hypertrophic disorders of skin
0.000 0.453 0.547
H53 Visual disturbances
0.000 0.456 0.544
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.457 0.543
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.457 0.543
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.457 0.543
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.457 0.543
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.457 0.543
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.457 0.543
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.457 0.543
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.457 0.543
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.457 0.543
M95.0 Acquired deformity of nose
0.000 0.458 0.542
E85 Amyloidosis
0.000 0.459 0.541
A48 Other bacterial diseases, not elsewhere classified
0.000 0.461 0.539
A44 Bartonellosis
0.000 0.461 0.539
A43 Nocardiosis
0.000 0.461 0.539
A42 Actinomycosis
0.000 0.461 0.539
A39 Meningococcal infection
0.000 0.461 0.539
A37 Whooping cough
0.000 0.461 0.539
A36 Diphtheria
0.000 0.461 0.539
A32 Listeriosis
0.000 0.461 0.539
A31 Infection due to other mycobacteria
0.000 0.461 0.539
A30 Leprosy [Hansen's disease]
0.000 0.461 0.539
A38 Scarlet fever
0.000 0.461 0.539
A35 Other tetanus
0.000 0.461 0.539
A34 Obstetrical tetanus
0.000 0.461 0.539
A33 Tetanus neonatorum
0.000 0.461 0.539
E11.3 With ophthalmic complications
0.000 0.461 0.539
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.461 0.539
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.462 0.538
L94 Other localised connective tissue disorders
0.000 0.462 0.538
L87 Transepidermal elimination disorders
0.000 0.462 0.538
L88 Pyoderma gangrenosum
0.000 0.462 0.538
L86 Keratoderma in diseases classified elsewhere
0.000 0.462 0.538
L80 Vitiligo
0.000 0.462 0.538
M86-M90 Other osteopathies
0.000 0.463 0.537
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.464 0.536
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.465 0.534
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.465 0.534
D51.2 Transcobalamin II deficiency
0.000 0.465 0.534
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.465 0.534
L03 Cellulitis
0.000 0.466 0.534
A49 Bacterial infection of unspecified site
0.000 0.467 0.533
M11.2 Other chondrocalcinosis
0.000 0.468 0.531
G80 Infantile cerebral palsy
0.000 0.469 0.531
G70.0 Myasthenia gravis
0.000 0.470 0.530
L93 Lupus erythematosus
0.000 0.470 0.530
G30.9 Alzheimer's disease, unspecified
0.000 0.471 0.529
H36 Retinal disorders in diseases classified elsewhere
0.000 0.471 0.529
N50.0 Atrophy of testis
0.528 0.472 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.000 0.472 0.528
L28 Lichen simplex chronicus and prurigo
0.000 0.475 0.525
M46 Other inflammatory spondylopathies
0.000 0.476 0.524
M00 Pyogenic arthritis
0.000 0.476 0.524
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.476 0.524
M65.3 Trigger finger
0.000 0.477 0.523
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.478 0.522
A41.9 Septicaemia, unspecified
0.000 0.479 0.521
A40 Streptococcal septicaemia
0.000 0.482 0.518
A08 Viral and other specified intestinal infections
0.000 0.482 0.517
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.483 0.517
G62.9 Polyneuropathy, unspecified
0.000 0.483 0.517
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.485 0.515
M99 Biomechanical lesions, not elsewhere classified
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M11.9 Crystal arthropathy, unspecified
0.000 0.486 0.514
M11.8 Other specified crystal arthropathies
0.000 0.486 0.514
M11.1 Familial chondrocalcinosis
0.000 0.486 0.514
M11.0 Hydroxyapatite deposition disease
0.000 0.486 0.514
L41.9 Parapsoriasis, unspecified
0.000 0.486 0.514
L41.8 Other parapsoriasis
0.000 0.486 0.514
L41.5 Retiform parapsoriasis
0.000 0.486 0.514
L41.4 Large plaque parapsoriasis
0.000 0.486 0.514
L41.3 Small plaque parapsoriasis
0.000 0.486 0.514
L41.2 Lymphomatoid papulosis
0.000 0.486 0.514
L41.1 Pityriasis lichenoides chronica
0.000 0.486 0.514
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.486 0.514
L44.9 Papulosquamous disorder, unspecified
0.000 0.486 0.514
L44.8 Other specified papulosquamous disorders
0.000 0.486 0.514
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.486 0.514
L44.3 Lichen ruber moniliformis
0.000 0.486 0.514
L44.2 Lichen striatus
0.000 0.486 0.514
L44.1 Lichen nitidus
0.000 0.486 0.514
L44.0 Pityriasis rubra pilaris
0.000 0.486 0.514
L13 Other bullous disorders
0.000 0.486 0.513
L12 Pemphigoid
0.000 0.486 0.513

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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