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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28375404
log Bayes Factor = 16.4264
Chromosome 6   position 32,614,917  (GRCh37) Explore rs28375404 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
# Top node
0.012 0.001 0.987
K90.0 Coeliac disease
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.004 0.996
J45 Asthma
0.000 0.004 0.995
K90 Intestinal malabsorption
0.000 0.007 0.993
J40-J47 Chronic lower respiratory diseases
0.001 0.007 0.992
E00-E07 Disorders of thyroid gland
0.000 0.007 0.993
Chapter X Diseases of the respiratory system
0.003 0.007 0.990
D64.9 Anaemia, unspecified
0.000 0.008 0.992
K90-K93 Other diseases of the digestive system
0.000 0.009 0.991
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.001 0.009 0.990
D64 Other anaemias
0.000 0.010 0.990
Chapter XI Diseases of the digestive system
0.000 0.010 0.990
D60-D64 Aplastic and other anaemias
0.000 0.010 0.990
Chapter IV Endocrine, nutritional and metabolic diseases
0.001 0.010 0.988
K20-K31 Diseases of oesophagus, stomach and duodenum
0.000 0.016 0.984
Chapter II Neoplasms
0.000 0.016 0.984
C44 Other malignant neoplasms of skin
0.000 0.018 0.982
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.019 0.981
M06.9 Rheumatoid arthritis, unspecified
0.000 0.020 0.980
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.020 0.980
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.023 0.977
C44.3 Skin of other and unspecified parts of face
0.000 0.023 0.977
K20 Oesophagitis
0.000 0.027 0.973
J20-J22 Other acute lower respiratory infections
0.001 0.045 0.953
K29 Gastritis and duodenitis
0.000 0.049 0.951
J44 Other chronic obstructive pulmonary disease
0.000 0.051 0.949
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.054 0.946
K29.8 Duodenitis
0.000 0.056 0.944
C44.7 Skin of lower limb, including hip
0.000 0.061 0.939
J00-J06 Acute upper respiratory infections
0.001 0.067 0.932
J22 Unspecified acute lower respiratory infection
0.000 0.070 0.930
K22 Other diseases of oesophagus
0.000 0.084 0.916
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.121 0.879
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.125 0.875
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.129 0.871
J46 Status asthmaticus
0.000 0.136 0.864
C44.0 Skin of lip
0.000 0.137 0.863
J02 Acute pharyngitis
0.000 0.138 0.862
K22.1 Ulcer of oesophagus
0.000 0.141 0.859
K22.2 Oesophageal obstruction
0.000 0.142 0.858
K70-K77 Diseases of liver
0.000 0.142 0.858
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.150 0.850
D00-D09 In situ neoplasms
0.000 0.150 0.850
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.160 0.840
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.161 0.839
K29.4 Chronic atrophic gastritis
0.000 0.168 0.832
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.169 0.831
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.001 0.169 0.831
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.169 0.831
C51-C58 Malignant neoplasms of female genital organs
0.000 0.170 0.830
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.170 0.830
M06 Other rheumatoid arthritis
0.087 0.171 0.742
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.180 0.820
D06 Carcinoma in situ of cervix uteri
0.000 0.183 0.817
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.185 0.815
D62 Acute posthaemorrhagic anaemia
0.000 0.187 0.813
J02.9 Acute pharyngitis, unspecified
0.000 0.188 0.812
E06 Thyroiditis
0.000 0.190 0.810
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.300 0.191 0.510
E10-E14 Diabetes mellitus
0.000 0.198 0.802
D06.9 Cervix, unspecified
0.000 0.206 0.794
Chapter I Certain infectious and parasitic diseases
0.001 0.211 0.788
M05-M14 Inflammatory polyarthropathies
0.212 0.213 0.575
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.217 0.783
E05.9 Thyrotoxicosis, unspecified
0.000 0.218 0.782
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.223 0.776
E50-E64 Other nutritional deficiencies
0.001 0.228 0.772
E20-E35 Disorders of other endocrine glands
0.001 0.230 0.769
K70 Alcoholic liver disease
0.000 0.235 0.765
K35-K38 Diseases of appendix
0.000 0.237 0.763
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.237 0.763
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.242 0.758
B35-B49 Mycoses
0.000 0.255 0.745
D80-D89 Certain disorders involving the immune mechanism
0.001 0.256 0.743
C92 Myeloid leukaemia
0.000 0.256 0.744
D45 Polycythaemia vera
0.000 0.260 0.740
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.264 0.736
D69 Purpura and other haemorrhagic conditions
0.000 0.265 0.735
C53 Malignant neoplasm of cervix uteri
0.000 0.265 0.735
C81 Hodgkin's disease
0.000 0.267 0.733
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.268 0.732
K27 Peptic ulcer, site unspecified
0.000 0.270 0.730
E11 Non-insulin-dependent diabetes mellitus
0.000 0.271 0.729
E07 Other disorders of thyroid
0.000 0.272 0.727
K26 Duodenal ulcer
0.000 0.278 0.722
C73 Malignant neoplasm of thyroid gland
0.000 0.278 0.722
J03 Acute tonsillitis
0.000 0.281 0.719
Chapter XVI Certain conditions originating in the perinatal period
0.009 0.284 0.708
E03.5 Myxoedema coma
0.000 0.286 0.714
E03.4 Atrophy of thyroid (acquired)
0.000 0.286 0.714
E03.3 Postinfectious hypothyroidism
0.000 0.286 0.714
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.286 0.714
E03.1 Congenital hypothyroidism without goitre
0.000 0.286 0.714
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.286 0.714
J45.8 Mixed asthma
0.000 0.286 0.713
J45.1 Nonallergic asthma
0.000 0.286 0.713
C64-C68 Malignant neoplasms of urinary tract
0.000 0.287 0.713
K22.9 Disease of oesophagus, unspecified
0.000 0.287 0.713
E11.3 With ophthalmic complications
0.000 0.287 0.713
B37 Candidiasis
0.000 0.287 0.713
K29.1 Other acute gastritis
0.000 0.287 0.713
K90.8 Other intestinal malabsorption
0.000 0.288 0.712
K90.3 Pancreatic steatorrhoea
0.000 0.288 0.712
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.288 0.712
K90.1 Tropical sprue
0.000 0.288 0.712
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.288 0.712
E00 Congenital iodine-deficiency syndrome
0.000 0.288 0.712
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.288 0.712
J41 Simple and mucopurulent chronic bronchitis
0.001 0.288 0.711
J04 Acute laryngitis and tracheitis
0.001 0.290 0.710
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.290 0.710
D64.8 Other specified anaemias
0.000 0.290 0.710
D64.4 Congenital dyserythropoietic anaemia
0.000 0.290 0.710
D64.3 Other sideroblastic anaemias
0.000 0.290 0.710
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.290 0.710
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.290 0.710
D64.0 Hereditary sideroblastic anaemia
0.000 0.290 0.710
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.290 0.710
K29.2 Alcoholic gastritis
0.000 0.293 0.707
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.293 0.707
K28 Gastrojejunal ulcer
0.000 0.294 0.706
K23 Disorders of oesophagus in diseases classified elsewhere
0.000 0.294 0.706
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.294 0.706
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.002 0.294 0.703
C44.2 Skin of ear and external auricular canal
0.000 0.295 0.705
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.296 0.704
C44.8 Overlapping lesion of skin
0.000 0.296 0.704
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.297 0.703
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.297 0.703
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.297 0.703
D55-D59 Haemolytic anaemias
0.001 0.297 0.702
J01 Acute sinusitis
0.001 0.298 0.701
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.299 0.701
C54 Malignant neoplasm of corpus uteri
0.000 0.300 0.700
C44.5 Skin of trunk
0.000 0.300 0.700
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.301 0.699
C44.4 Skin of scalp and neck
0.000 0.307 0.693
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.310 0.690
K70.9 Alcoholic liver disease, unspecified
0.000 0.310 0.690
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.310 0.690
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.311 0.689
M80-M85 Disorders of bone density and structure
0.234 0.313 0.453
J21 Acute bronchiolitis
0.001 0.315 0.683
C44.1 Skin of eyelid, including canthus
0.000 0.316 0.684
K29.9 Gastroduodenitis, unspecified
0.000 0.318 0.682
K22.8 Other specified diseases of oesophagus
0.000 0.318 0.682
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.000 0.319 0.681
E06.3 Autoimmune thyroiditis
0.000 0.321 0.679
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.321 0.678
C95 Leukaemia of unspecified cell type
0.000 0.321 0.678
C94 Other leukaemias of specified cell type
0.000 0.321 0.678
C93 Monocytic leukaemia
0.000 0.321 0.678
C86 Other specified types of T/NK-cell lymphoma
0.000 0.321 0.678
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.321 0.678
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.325 0.675
D69.6 Thrombocytopenia, unspecified
0.000 0.325 0.675
J45.0 Predominantly allergic asthma
0.000 0.328 0.671
D75 Other diseases of blood and blood-forming organs
0.000 0.330 0.670
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.330 0.669
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.001 0.331 0.668
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.332 0.668
K92 Other diseases of digestive system
0.000 0.333 0.667
C53.9 Cervix uteri, unspecified
0.000 0.334 0.666
J95-J99 Other diseases of the respiratory system
0.002 0.335 0.663
Z85 Personal history of malignant neoplasm
0.000 0.337 0.663
E55 Vitamin D deficiency
0.000 0.340 0.660
K76 Other diseases of liver
0.000 0.343 0.657
J20 Acute bronchitis
0.001 0.343 0.656
K22.3 Perforation of oesophagus
0.000 0.343 0.657
K22.4 Dyskinesia of oesophagus
0.000 0.344 0.656
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.344 0.656
K72 Hepatic failure, not elsewhere classified
0.000 0.346 0.654
B37.8 Candidiasis of other sites
0.000 0.347 0.653
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.000 0.348 0.652
E03.8 Other specified hypothyroidism
0.000 0.348 0.652
K29.3 Chronic superficial gastritis
0.000 0.350 0.649
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.351 0.649
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.352 0.648
B07 Viral warts
0.000 0.354 0.646
C67 Malignant neoplasm of bladder
0.000 0.355 0.645
C09 Malignant neoplasm of tonsil
0.000 0.355 0.644
C60-C63 Malignant neoplasms of male genital organs
0.000 0.362 0.638
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.001 0.362 0.637
D46 Myelodysplastic syndromes
0.000 0.363 0.636
C91 Lymphoid leukaemia
0.000 0.365 0.635
Chapter XXII Codes for special purposes
0.009 0.366 0.626
C88 Malignant immunoproliferative diseases
0.000 0.367 0.633
J00 Acute nasopharyngitis [common cold]
0.001 0.368 0.632
C92.0 Acute myeloid leukaemia
0.000 0.369 0.631
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.370 0.630
C82.6 Cutaneous follicle centre lymphoma
0.000 0.370 0.630
C82.5 Diffuse follicle centre lymphoma
0.000 0.370 0.630
C82.4 Follicular lymphoma grade IIIb
0.000 0.370 0.630
C82.3 Follicular lymphoma grade IIIa
0.000 0.370 0.630
C82.2 Large cell, follicular
0.000 0.370 0.630
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.370 0.630
C82.0 Small cleaved cell, follicular
0.000 0.370 0.630
E21.0 Primary hyperparathyroidism
0.000 0.372 0.628
K29.5 Chronic gastritis, unspecified
0.000 0.373 0.627
K90.9 Intestinal malabsorption, unspecified
0.000 0.375 0.624
E05.8 Other thyrotoxicosis
0.000 0.376 0.624
E05.5 Thyroid crisis or storm
0.000 0.376 0.624
E05.4 Thyrotoxicosis factitia
0.000 0.376 0.624
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.376 0.624
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.376 0.624
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.376 0.624
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.376 0.624
E11.4 With neurological complications
0.000 0.381 0.619
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.382 0.618
J02.0 Streptococcal pharyngitis
0.000 0.382 0.618
D68 Other coagulation defects
0.000 0.383 0.616
K77 Liver disorders in diseases classified elsewhere
0.000 0.385 0.615
K73 Chronic hepatitis, not elsewhere classified
0.000 0.385 0.615
K71 Toxic liver disease
0.000 0.385 0.615
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.000 0.385 0.615
C85.1 B-cell lymphoma, unspecified
0.000 0.386 0.614
D05 Carcinoma in situ of breast
0.000 0.388 0.612
E29 Testicular dysfunction
0.001 0.389 0.610
D50-D53 Nutritional anaemias
0.000 0.390 0.609
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.391 0.609
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.391 0.609
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.391 0.609
D47.2 Monoclonal gammopathy
0.000 0.391 0.609
K92.0 Haematemesis
0.000 0.391 0.609
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.392 0.608
C54.1 Endometrium
0.000 0.393 0.607
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.397 0.602
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.397 0.602
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.397 0.602
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.397 0.602
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.000 0.397 0.602
B37.0 Candidal stomatitis
0.000 0.401 0.599
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.401 0.599
C67.9 Bladder, unspecified
0.000 0.402 0.598
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.404 0.596
C74 Malignant neoplasm of adrenal gland
0.000 0.404 0.596
D67 Hereditary factor IX deficiency
0.001 0.404 0.596
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.001 0.404 0.596
C57 Malignant neoplasm of other and unspecified female genital organs
0.000 0.405 0.595
C58 Malignant neoplasm of placenta
0.000 0.405 0.595
C55 Malignant neoplasm of uterus, part unspecified
0.000 0.405 0.595
C52 Malignant neoplasm of vagina
0.000 0.405 0.595
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.405 0.595
C85.0 Lymphosarcoma
0.000 0.405 0.595
M05 Seropositive rheumatoid arthritis
0.127 0.405 0.468
M06.8 Other specified rheumatoid arthritis
0.062 0.406 0.532
M06.4 Inflammatory polyarthropathy
0.062 0.406 0.532
M06.3 Rheumatoid nodule
0.062 0.406 0.532
M06.2 Rheumatoid bursitis
0.062 0.406 0.532
M06.1 Adult-onset Still's disease
0.062 0.406 0.532
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.000 0.407 0.593
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.407 0.593
B90-B94 Sequelae of infectious and parasitic diseases
0.001 0.408 0.592
C51 Malignant neoplasm of vulva
0.000 0.409 0.591
D86 Sarcoidosis
0.000 0.410 0.590
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.410 0.590
D75.1 Secondary polycythaemia
0.000 0.413 0.587
D06.7 Other parts of cervix
0.000 0.414 0.586
D06.1 Exocervix
0.000 0.414 0.586
D06.0 Endocervix
0.000 0.414 0.586
E40-E46 Malnutrition
0.001 0.414 0.584
M06.0 Seronegative rheumatoid arthritis
0.061 0.417 0.522
K75 Other inflammatory liver diseases
0.000 0.418 0.582
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.419 0.581
E06.9 Thyroiditis, unspecified
0.000 0.419 0.581
E06.5 Other chronic thyroiditis
0.000 0.419 0.581
E06.4 Drug-induced thyroiditis
0.000 0.419 0.581
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.419 0.581
E06.1 Subacute thyroiditis
0.000 0.419 0.581
E06.0 Acute thyroiditis
0.000 0.419 0.581
B35 Dermatophytosis
0.000 0.419 0.581
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.419 0.581
C81.9 Hodgkin's disease, unspecified
0.000 0.419 0.581
K76.9 Liver disease, unspecified
0.000 0.420 0.580
E55.9 Vitamin D deficiency, unspecified
0.000 0.420 0.579
E07.9 Disorder of thyroid, unspecified
0.000 0.422 0.578
K35 Acute appendicitis
0.000 0.422 0.578
K65-K67 Diseases of peritoneum
0.000 0.423 0.577
K22.0 Achalasia of cardia
0.000 0.425 0.575
E12 Malnutrition-related diabetes mellitus
0.000 0.425 0.575
D70 Agranulocytosis
0.000 0.425 0.575
K29.0 Acute haemorrhagic gastritis
0.000 0.426 0.574
E23 Hypofunction and other disorders of pituitary gland
0.001 0.427 0.573
K70.4 Alcoholic hepatic failure
0.000 0.427 0.573
E27 Other disorders of adrenal gland
0.001 0.427 0.572
M00-M03 Infectious arthropathies
0.227 0.427 0.345
K70.3 Alcoholic cirrhosis of liver
0.000 0.428 0.572
K37 Unspecified appendicitis
0.000 0.430 0.570
M91-M94 Chondropathies
0.211 0.430 0.360
M07 Psoriatic and enteropathic arthropathies
0.137 0.430 0.433
M60-M63 Disorders of muscles
0.228 0.430 0.341
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.431 0.568
M81 Osteoporosis without pathological fracture
0.128 0.433 0.439
D09 Carcinoma in situ of other and unspecified sites
0.000 0.433 0.566
J03.9 Acute tonsillitis, unspecified
0.000 0.434 0.566
B99-B99 Other infectious diseases
0.001 0.434 0.565
B85-B89 Pediculosis, acariasis and other infestations
0.001 0.434 0.565
B50-B64 Protozoal diseases
0.001 0.434 0.565
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.001 0.434 0.565
A75-A79 Rickettsioses
0.001 0.434 0.565
A70-A74 Other diseases caused by chlamydiae
0.001 0.434 0.565
A65-A69 Other spirochaetal diseases
0.001 0.434 0.565
A20-A28 Certain zoonotic bacterial diseases
0.001 0.434 0.565
A15-A19 Tuberculosis
0.001 0.434 0.565
J95 Postprocedural respiratory disorders, not elsewhere classified
0.001 0.435 0.564
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.000 0.435 0.565
M14 Arthropathies in other diseases classified elsewhere
0.152 0.436 0.412
M12 Other specific arthropathies
0.152 0.436 0.412
M09 Juvenile arthritis in diseases classified elsewhere
0.152 0.436 0.412
M08 Juvenile arthritis
0.152 0.436 0.412
J60-J70 Lung diseases due to external agents
0.003 0.436 0.561
B20-B24 Human immunodeficiency virus [HIV] disease
0.001 0.437 0.562
K40-K46 Hernia
0.000 0.437 0.563
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.439 0.561
C13 Malignant neoplasm of hypopharynx
0.000 0.439 0.561
C11 Malignant neoplasm of nasopharynx
0.000 0.439 0.561
C10 Malignant neoplasm of oropharynx
0.000 0.439 0.561
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.439 0.561
C06 Malignant neoplasm of other and unspecified parts of mouth
0.000 0.439 0.561
C05 Malignant neoplasm of palate
0.000 0.439 0.561
C04 Malignant neoplasm of floor of mouth
0.000 0.439 0.561
C03 Malignant neoplasm of gum
0.000 0.439 0.561
C00 Malignant neoplasm of lip
0.000 0.439 0.561
C12 Malignant neoplasm of pyriform sinus
0.000 0.439 0.561
C07 Malignant neoplasm of parotid gland
0.000 0.439 0.561
K31 Other diseases of stomach and duodenum
0.000 0.441 0.559
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.443 0.557
D74 Methaemoglobinaemia
0.000 0.443 0.557
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.443 0.557
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.443 0.557
B37.9 Candidiasis, unspecified
0.000 0.444 0.556
B25-B34 Other viral diseases
0.000 0.445 0.555
D61 Other aplastic anaemias
0.001 0.446 0.553
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.446 0.553
E63 Other nutritional deficiencies
0.001 0.446 0.553
E56 Other vitamin deficiencies
0.001 0.446 0.553
E51 Thiamine deficiency
0.001 0.446 0.553
E50 Vitamin A deficiency
0.001 0.446 0.553
E60 Dietary zinc deficiency
0.001 0.446 0.553
E59 Dietary selenium deficiency
0.001 0.446 0.553
E58 Dietary calcium deficiency
0.001 0.446 0.553
E54 Ascorbic acid deficiency
0.001 0.446 0.553
E52 Niacin deficiency [pellagra]
0.001 0.446 0.553
E21.3 Hyperparathyroidism, unspecified
0.000 0.447 0.553
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.000 0.448 0.552
K38 Other diseases of appendix
0.000 0.448 0.552
E35 Disorders of endocrine glands in diseases classified elsewhere
0.001 0.448 0.551
E32 Diseases of thymus
0.001 0.448 0.551
E31 Polyglandular dysfunction
0.001 0.448 0.551
E30 Disorders of puberty, not elsewhere classified
0.001 0.448 0.551
E26 Hyperaldosteronism
0.001 0.448 0.551
E25 Adrenogenital disorders
0.001 0.448 0.551
E20 Hypoparathyroidism
0.001 0.448 0.551
E04 Other non-toxic goitre
0.000 0.448 0.552
D68.9 Coagulation defect, unspecified
0.000 0.448 0.551
J04.0 Acute laryngitis
0.000 0.449 0.551
M11 Other crystal arthropathies
0.147 0.451 0.402
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.452 0.548
K70.0 Alcoholic fatty liver
0.000 0.452 0.548
K74 Fibrosis and cirrhosis of liver
0.000 0.452 0.548
K36 Other appendicitis
0.000 0.452 0.547
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.453 0.547
K26.4 Chronic or unspecified with haemorrhage
0.000 0.454 0.546
C09.9 Tonsil, unspecified
0.000 0.454 0.545
D72 Other disorders of white blood cells
0.000 0.455 0.545
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.457 0.542
K22.5 Diverticulum of oesophagus, acquired
0.000 0.458 0.542
C83.3 Large cell (diffuse)
0.000 0.458 0.541
E53 Deficiency of other B group vitamins
0.001 0.461 0.539
D47.1 Chronic myeloproliferative disease
0.000 0.462 0.538
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.224 0.462 0.314
K44 Diaphragmatic hernia
0.000 0.463 0.537
J01.9 Acute sinusitis, unspecified
0.000 0.463 0.536
J06.9 Acute upper respiratory infection, unspecified
0.000 0.465 0.535
B48 Other mycoses, not elsewhere classified
0.000 0.466 0.534
B47 Mycetoma
0.000 0.466 0.534
B46 Zygomycosis
0.000 0.466 0.534
B45 Cryptococcosis
0.000 0.466 0.534
B43 Chromomycosis and phaeomycotic abscess
0.000 0.466 0.534
B42 Sporotrichosis
0.000 0.466 0.534
B41 Paracoccidioidomycosis
0.000 0.466 0.534
B40 Blastomycosis
0.000 0.466 0.534
B39 Histoplasmosis
0.000 0.466 0.534
B38 Coccidioidomycosis
0.000 0.466 0.534
B36 Other superficial mycoses
0.000 0.466 0.534
D84 Other immunodeficiencies
0.001 0.466 0.533
D83 Common variable immunodeficiency
0.001 0.466 0.533
D82 Immunodeficiency associated with other major defects
0.001 0.466 0.533
D81 Combined immunodeficiencies
0.001 0.466 0.533
D80 Immunodeficiency with predominantly antibody defects
0.001 0.466 0.533
C92.9 Myeloid leukaemia, unspecified
0.000 0.467 0.533
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.467 0.533
C92.7 Other myeloid leukaemia
0.000 0.467 0.533
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.467 0.533
C92.5 Acute myelomonocytic leukaemia
0.000 0.467 0.533
C92.4 Acute promyelocytic leukaemia
0.000 0.467 0.533
C92.3 Myeloid sarcoma
0.000 0.467 0.533
C92.2 Subacute myeloid leukaemia
0.000 0.467 0.533
B37.3 Candidiasis of vulva and vagina
0.000 0.467 0.533
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.468 0.532
A80-A89 Viral infections of the central nervous system
0.001 0.468 0.531
D63.0 Anaemia in neoplastic disease
0.000 0.469 0.531
E13 Other specified diabetes mellitus
0.000 0.471 0.529
K25 Gastric ulcer
0.000 0.471 0.529
C01 Malignant neoplasm of base of tongue
0.000 0.471 0.528
D04 Carcinoma in situ of skin
0.000 0.471 0.528
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.472 0.528
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.472 0.528
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.472 0.528
D47.4 Osteomyelofibrosis
0.000 0.472 0.528
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.472 0.528
D69.9 Haemorrhagic condition, unspecified
0.000 0.473 0.527
D69.8 Other specified haemorrhagic conditions
0.000 0.473 0.527
D69.4 Other primary thrombocytopenia
0.000 0.473 0.527
D69.2 Other nonthrombocytopenic purpura
0.000 0.473 0.527
D69.1 Qualitative platelet defects
0.000 0.473 0.527
D69.0 Allergic purpura
0.000 0.473 0.527
B65-B83 Helminthiases
0.001 0.473 0.526
C53.8 Overlapping lesion of cervix uteri
0.000 0.473 0.527
C53.1 Exocervix
0.000 0.473 0.527
C53.0 Endocervix
0.000 0.473 0.527
E10 Insulin-dependent diabetes mellitus
0.000 0.473 0.526
C81.7 Other Hodgkin's disease
0.000 0.474 0.526
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.474 0.526
C81.3 Lymphocytic depletion
0.000 0.474 0.526
C81.2 Mixed cellularity
0.000 0.474 0.526
C81.1 Nodular sclerosis
0.000 0.474 0.526
C81.0 Lymphocytic predominance
0.000 0.474 0.526
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.475 0.525
D66 Hereditary factor VIII deficiency
0.001 0.475 0.524
Z85.5 Personal history of malignant neoplasm of urinary tract
0.000 0.475 0.525
Chapter XII Diseases of the skin and subcutaneous tissue
0.001 0.476 0.523
B49 Unspecified mycosis
0.000 0.476 0.523
K27.7 Chronic without haemorrhage or perforation
0.000 0.477 0.523
K27.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.477 0.523
K27.5 Chronic or unspecified with perforation
0.000 0.477 0.523
K27.4 Chronic or unspecified with haemorrhage
0.000 0.477 0.523
K27.3 Acute without haemorrhage or perforation
0.000 0.477 0.523
K27.2 Acute with both haemorrhage and perforation
0.000 0.477 0.523
K27.1 Acute with perforation
0.000 0.477 0.523
K27.0 Acute with haemorrhage
0.000 0.477 0.523
E11.8 With unspecified complications
0.000 0.477 0.522
E11.7 With multiple complications
0.000 0.477 0.522
E07.1 Dyshormogenetic goitre
0.000 0.478 0.521
E07.0 Hypersecretion of calcitonin
0.000 0.478 0.521
C67.4 Posterior wall of bladder
0.000 0.478 0.522
M40-M43 Deforming dorsopathies
0.205 0.480 0.314
A63.0 Anogenital (venereal) warts
0.000 0.481 0.519
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.481 0.519
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.482 0.518
K26.2 Acute with both haemorrhage and perforation
0.000 0.482 0.518
K26.1 Acute with perforation
0.000 0.482 0.518
K26.0 Acute with haemorrhage
0.000 0.482 0.518
E14 Unspecified diabetes mellitus
0.000 0.483 0.516
K70.1 Alcoholic hepatitis
0.000 0.484 0.516
M86-M90 Other osteopathies
0.272 0.484 0.243
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.484 0.515
J03.0 Streptococcal tonsillitis
0.000 0.484 0.515
P90-P96 Other disorders originating in the perinatal period
0.006 0.486 0.507
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.006 0.486 0.507
P75-P78 Digestive system disorders of fetus and newborn
0.006 0.486 0.507
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.006 0.486 0.507
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.006 0.486 0.507
P35-P39 Infections specific to the perinatal period
0.006 0.486 0.507
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.006 0.486 0.507
P10-P15 Birth trauma
0.006 0.486 0.507
P05-P08 Disorders related to length of gestation and fetal growth
0.006 0.486 0.507
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.006 0.486 0.507
E24 Cushing's syndrome
0.001 0.487 0.512
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.488 0.511
C66 Malignant neoplasm of ureter
0.000 0.488 0.511
B37.7 Candidal septicaemia
0.000 0.489 0.511
B37.6 Candidal endocarditis
0.000 0.489 0.511
B37.5 Candidal meningitis
0.000 0.489 0.511
B37.4 Candidiasis of other urogenital sites
0.000 0.489 0.511
B37.2 Candidiasis of skin and nail
0.000 0.489 0.511
B37.1 Pulmonary candidiasis
0.000 0.489 0.511
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.489 0.510
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.489 0.510
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.489 0.510
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.489 0.510
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.489 0.510
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.489 0.510
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.489 0.510
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.489 0.510
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.001 0.489 0.510
J41.1 Mucopurulent chronic bronchitis
0.001 0.489 0.510
J41.0 Simple chronic bronchitis
0.001 0.489 0.510
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.490 0.510
J04.2 Acute laryngotracheitis
0.001 0.491 0.509
J04.1 Acute tracheitis
0.001 0.491 0.509
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.491 0.509
K93.1 Megacolon in Chagas' disease
0.000 0.491 0.509
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.491 0.509
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.491 0.509
D60.8 Other acquired pure red cell aplasias
0.000 0.491 0.509
D60.1 Transient acquired pure red cell aplasia
0.000 0.491 0.509

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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