TreeWAS – Variant ID: rs28380862

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
M35 Other systemic involvement of connective tissue	0.000	0.000	1.000
L40.0 Psoriasis vulgaris	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.001	0.999
M35.3 Polymyalgia rheumatica	0.000	0.001	0.999
M05-M14 Inflammatory polyarthropathies	0.000	0.002	0.998
M07.39 Other psoriatic arthropathies (Site unspecified)	0.997	0.003	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.003	0.997
E10.9 Without complications	0.000	0.003	0.997
M07.3 Other psoriatic arthropathies	0.997	0.003	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.006	0.994
E00-E07 Disorders of thyroid gland	0.000	0.007	0.993
E03 Other hypothyroidism	0.000	0.007	0.993
M05 Seropositive rheumatoid arthritis	0.000	0.010	0.990
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.016	0.984
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.020	0.980
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.020	0.980
M45 Ankylosing spondylitis	0.000	0.021	0.979
M07.30 Other psoriatic arthropathies (Multiple sites)	0.976	0.024	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.000	0.025	0.975
M20-M25 Other joint disorders	0.000	0.025	0.975
M45-M49 Spondylopathies	0.000	0.027	0.973
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.028	0.972
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.028	0.972
E10-E14 Diabetes mellitus	0.000	0.029	0.971
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.031	0.969
E05.9 Thyrotoxicosis, unspecified	0.000	0.038	0.962
M34 Systemic sclerosis	0.000	0.043	0.957
M06.0 Seronegative rheumatoid arthritis	0.000	0.051	0.949
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.055	0.945
E10.3 With ophthalmic complications	0.000	0.093	0.907
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.098	0.902
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.100	0.900
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.105	0.895
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.111	0.889
M34.9 Systemic sclerosis, unspecified	0.000	0.120	0.880
E10.4 With neurological complications	0.000	0.120	0.880
M07.34 Other psoriatic arthropathies (Hand)	0.879	0.120	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.130	0.870
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.137	0.863
E10.5 With peripheral circulatory complications	0.000	0.139	0.861
M07.38 Other psoriatic arthropathies (Other)	0.859	0.141	0.000
E10.0 With coma	0.000	0.143	0.857
M34.8 Other forms of systemic sclerosis	0.000	0.145	0.855
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.854	0.146	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.152	0.848
M60-M63 Disorders of muscles	0.000	0.153	0.846
M35.1 Other overlap syndromes	0.000	0.154	0.846
E10.1 With ketoacidosis	0.000	0.155	0.845
E10.2 With renal complications	0.000	0.156	0.844
E04 Other non-toxic goitre	0.000	0.156	0.844
M06.4 Inflammatory polyarthropathy	0.000	0.159	0.841
M34.1 CR(E)ST syndrome	0.000	0.161	0.839
M07 Psoriatic and enteropathic arthropathies	0.416	0.167	0.417
M07.31 Other psoriatic arthropathies (Shoulder region)	0.829	0.171	0.000
L40.8 Other psoriasis	0.826	0.174	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.180	0.820
L40.1 Generalised pustular psoriasis	0.818	0.182	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.816	0.184	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.187	0.813
M35.7 Hypermobility syndrome	0.000	0.188	0.812
E10.6 With other specified complications	0.000	0.189	0.811
E07 Other disorders of thyroid	0.000	0.202	0.798
M32 Systemic lupus erythematosus	0.000	0.206	0.794
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.207	0.793
E16 Other disorders of pancreatic internal secretion	0.000	0.213	0.786
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.217	0.783
L40.4 Guttate psoriasis	0.778	0.222	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.222	0.778
M62 Other disorders of muscle	0.000	0.223	0.776
M07.36 Other psoriatic arthropathies (Lower leg)	0.775	0.225	0.000
E06 Thyroiditis	0.000	0.233	0.767
E04.9 Non-toxic goitre, unspecified	0.000	0.241	0.759
M30 Polyarteritis nodosa and related conditions	0.000	0.244	0.756
M62.8 Other specified disorders of muscle	0.000	0.248	0.752
M06.3 Rheumatoid nodule	0.000	0.248	0.751
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.249	0.751
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.254	0.746
M11 Other crystal arthropathies	0.000	0.274	0.726
M14 Arthropathies in other diseases classified elsewhere	0.000	0.276	0.723
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.283	0.717
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
M06.1 Adult-onset Still's disease	0.000	0.283	0.717
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.283	0.717
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.283	0.717
M35.5 Multifocal fibrosclerosis	0.000	0.283	0.717
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.283	0.717
M35.2 Behcet's disease	0.000	0.283	0.717
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.284	0.716
M08 Juvenile arthritis	0.000	0.284	0.716
E16.2 Hypoglycaemia, unspecified	0.000	0.285	0.715
E10.7 With multiple complications	0.000	0.285	0.715
M07.33 Other psoriatic arthropathies (Forearm)	0.714	0.285	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.714	0.285	0.000
M35.8 Other specified systemic involvement of connective tissue	0.000	0.287	0.713
M12 Other specific arthropathies	0.000	0.287	0.713
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.288	0.712
E00 Congenital iodine-deficiency syndrome	0.000	0.288	0.712
E03.5 Myxoedema coma	0.000	0.288	0.712
E03.4 Atrophy of thyroid (acquired)	0.000	0.288	0.712
E03.3 Postinfectious hypothyroidism	0.000	0.288	0.712
M05.8 Other seropositive rheumatoid arthritis	0.000	0.290	0.710
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.290	0.710
M05.2 Rheumatoid vasculitis	0.000	0.290	0.710
M05.1 Rheumatoid lung disease	0.000	0.290	0.710
M05.0 Felty's syndrome	0.000	0.290	0.710
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.294	0.705
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.294	0.705
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.294	0.705
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.294	0.705
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.294	0.705
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.294	0.705
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.294	0.705
E05.5 Thyroid crisis or storm	0.000	0.297	0.703
E05.4 Thyrotoxicosis factitia	0.000	0.297	0.703
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.297	0.703
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.297	0.703
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.298	0.702
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.298	0.702
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.298	0.702
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.298	0.702
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.298	0.702
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.298	0.702
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.298	0.702
E04.2 Non-toxic multinodular goitre	0.000	0.300	0.700
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.301	0.699
E12 Malnutrition-related diabetes mellitus	0.000	0.304	0.696
M62.80 Other specified disorders of muscle (Multiple sites)	0.000	0.305	0.695
M65-M68 Disorders of synovium and tendon	0.000	0.305	0.695
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.312	0.688
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.313	0.687
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.313	0.686
M34.0 Progressive systemic sclerosis	0.000	0.313	0.686
E10.8 With unspecified complications	0.000	0.318	0.682
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.318	0.681
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.319	0.680
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.319	0.680
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.319	0.680
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.319	0.680
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.319	0.680
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.319	0.680
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.000	0.321	0.679
M10 Gout	0.000	0.321	0.679
K90 Intestinal malabsorption	0.000	0.329	0.671
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.330	0.670
M49 Spondylopathies in diseases classified elsewhere	0.000	0.331	0.669
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.333	0.667
E05.8 Other thyrotoxicosis	0.000	0.335	0.665
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.335	0.665
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.335	0.665
M46 Other inflammatory spondylopathies	0.000	0.337	0.662
M62.81 Other specified disorders of muscle (Shoulder region)	0.000	0.344	0.655
M31 Other necrotising vasculopathies	0.000	0.357	0.643
M06.34 Rheumatoid nodule (Hand)	0.000	0.360	0.639
E40-E46 Malnutrition	0.000	0.362	0.637
E03.1 Congenital hypothyroidism without goitre	0.000	0.363	0.637
M00-M03 Infectious arthropathies	0.000	0.367	0.633
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.369	0.631
E07.8 Other specified disorders of thyroid	0.000	0.370	0.630
M62.89 Other specified disorders of muscle (Site unspecified)	0.000	0.371	0.629
E15 Nondiabetic hypoglycaemic coma	0.000	0.381	0.618
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.384	0.616
M80-M85 Disorders of bone density and structure	0.000	0.388	0.612
E04.0 Non-toxic diffuse goitre	0.000	0.389	0.611
E07.9 Disorder of thyroid, unspecified	0.000	0.390	0.610
M63 Disorders of muscle in diseases classified elsewhere	0.000	0.393	0.607
M61 Calcification and ossification of muscle	0.000	0.393	0.607
E04.8 Other specified non-toxic goitre	0.000	0.395	0.605
M66 Spontaneous rupture of synovium and tendon	0.000	0.395	0.605
E06.3 Autoimmune thyroiditis	0.000	0.396	0.604
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.397	0.603
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.397	0.603
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.397	0.603
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.397	0.603
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.397	0.603
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.397	0.603
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.397	0.603
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.397	0.603
M07.6 Other enteropathic arthropathies	0.298	0.403	0.299
M07.5 Arthropathy in ulcerative colitis	0.298	0.403	0.299
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.298	0.403	0.299
M07.2 Psoriatic spondylitis	0.298	0.403	0.299
M07.1 Arthritis mutilans	0.298	0.403	0.299
M07.0 Distal interphalangeal psoriatic arthropathy	0.298	0.403	0.299
E13 Other specified diabetes mellitus	0.000	0.407	0.592
M80 Osteoporosis with pathological fracture	0.000	0.419	0.581
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.420	0.580
M13 Other arthritis	0.000	0.421	0.579
M62.82 Other specified disorders of muscle (Upper arm)	0.000	0.425	0.575
E07.1 Dyshormogenetic goitre	0.000	0.428	0.572
E07.0 Hypersecretion of calcitonin	0.000	0.428	0.572
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.430	0.569
M32.8 Other forms of systemic lupus erythematosus	0.000	0.430	0.569
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.430	0.569
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.433	0.566
M22 Disorders of patella	0.000	0.434	0.566
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.436	0.564
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.436	0.564
E16.4 Abnormal secretion of gastrin	0.000	0.436	0.564
E16.3 Increased secretion of glucagon	0.000	0.436	0.564
M30.0 Polyarteritis nodosa	0.000	0.436	0.564
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.443	0.557
M62.9 Disorder of muscle, unspecified	0.000	0.443	0.557
M62.4 Contracture of muscle	0.000	0.443	0.557
M62.3 Immobility syndrome (paraplegic)	0.000	0.443	0.557
M62.2 Ischaemic infarction of muscle	0.000	0.443	0.557
M62.1 Other rupture of muscle (nontraumatic)	0.000	0.443	0.557
E06.9 Thyroiditis, unspecified	0.000	0.448	0.552
E06.5 Other chronic thyroiditis	0.000	0.450	0.550
E06.4 Drug-induced thyroiditis	0.000	0.450	0.550
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.450	0.550
E06.1 Subacute thyroiditis	0.000	0.450	0.550
E06.0 Acute thyroiditis	0.000	0.450	0.550
E50-E64 Other nutritional deficiencies	0.000	0.450	0.550
M10.0 Idiopathic gout	0.000	0.451	0.549
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.452	0.547
M66.2 Spontaneous rupture of extensor tendons	0.000	0.453	0.547
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.458	0.542
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.458	0.542
M30.2 Juvenile polyarteritis	0.000	0.458	0.542
M62.87 Other specified disorders of muscle (Ankle and foot)	0.000	0.461	0.539
M62.83 Other specified disorders of muscle (Forearm)	0.000	0.461	0.539
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.461	0.539
M06.38 Rheumatoid nodule (Other)	0.000	0.461	0.539
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.461	0.539
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.461	0.539
M06.33 Rheumatoid nodule (Forearm)	0.000	0.461	0.539
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.461	0.539
M11.2 Other chondrocalcinosis	0.000	0.462	0.538
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.464	0.536
M31.3 Wegener's granulomatosis	0.000	0.464	0.536
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.464	0.536
M21 Other acquired deformities of limbs	0.000	0.467	0.533
M62.0 Diastasis of muscle	0.000	0.468	0.532
M60 Myositis	0.000	0.469	0.531
M14.6 Neuropathic arthropathy	0.000	0.473	0.527
E14 Unspecified diabetes mellitus	0.000	0.475	0.525
M62.6 Muscle strain	0.000	0.476	0.524
K90.8 Other intestinal malabsorption	0.000	0.477	0.523
M11.8 Other specified crystal arthropathies	0.000	0.479	0.520
M11.1 Familial chondrocalcinosis	0.000	0.479	0.520
M11.0 Hydroxyapatite deposition disease	0.000	0.479	0.520
M14.8 Arthropathies in other specified diseases classified elsewhere	0.000	0.481	0.519
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.000	0.481	0.519
M14.4 Arthropathy in amyloidosis	0.000	0.481	0.519
M14.3 Lipoid dermatoarthritis	0.000	0.481	0.519
M14.2 Diabetic arthropathy	0.000	0.481	0.519
M14.1 Crystal arthropathy in other metabolic disorders	0.000	0.481	0.519
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.000	0.481	0.519
M86-M90 Other osteopathies	0.000	0.484	0.516
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.486	0.514
M06.18 Adult-onset Still's disease (Other)	0.000	0.486	0.514
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.486	0.514
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.486	0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.486	0.514
M06.14 Adult-onset Still's disease (Hand)	0.000	0.486	0.514
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.486	0.514
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.486	0.514
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.486	0.514
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.486	0.514
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.486	0.514
M06.28 Rheumatoid bursitis (Other)	0.000	0.486	0.514
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.486	0.514
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.486	0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.486	0.514
M06.24 Rheumatoid bursitis (Hand)	0.000	0.486	0.514
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.486	0.514
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.486	0.514
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.486	0.514
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.486	0.514
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.486	0.514
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.486	0.514
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.486	0.514
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.486	0.514
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.486	0.514
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.486	0.514
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.486	0.514
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.486	0.514
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.486	0.514
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.486	0.514
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.486	0.514
M08.9 Juvenile arthritis, unspecified	0.000	0.487	0.513
M08.8 Other juvenile arthritis	0.000	0.487	0.513
M08.4 Pauciarticular juvenile arthritis	0.000	0.487	0.513
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.487	0.513
M08.2 Juvenile arthritis with systemic onset	0.000	0.487	0.513
M08.1 Juvenile ankylosing spondylitis	0.000	0.487	0.513
M08.0 Juvenile rheumatoid arthritis	0.000	0.487	0.513
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.000	0.487	0.513
M09.2 Juvenile arthritis in ulcerative colitis	0.000	0.487	0.513
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.000	0.487	0.513
M09.0 Juvenile arthritis in psoriasis	0.000	0.487	0.513
M11.9 Crystal arthropathy, unspecified	0.000	0.488	0.512
E03.8 Other specified hypothyroidism	0.000	0.489	0.511
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.489	0.511
M12.5 Traumatic arthropathy	0.000	0.489	0.511
M12.4 Intermittent hydrarthrosis	0.000	0.489	0.511
M12.3 Palindromic rheumatism	0.000	0.489	0.511
M12.1 Kaschin-Beck disease	0.000	0.489	0.511
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.489	0.511
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.489	0.511
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.489	0.511
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.489	0.511
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.489	0.511
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.489	0.511
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.489	0.511
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.489	0.511
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.489	0.511
M05.09 Felty's syndrome (Site unspecified)	0.000	0.491	0.509
M05.08 Felty's syndrome (Other)	0.000	0.491	0.509
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.491	0.509
M05.06 Felty's syndrome (Lower leg)	0.000	0.491	0.509
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.491	0.509
M05.04 Felty's syndrome (Hand)	0.000	0.491	0.509
M05.03 Felty's syndrome (Forearm)	0.000	0.491	0.509
M05.02 Felty's syndrome (Upper arm)	0.000	0.491	0.509
M05.01 Felty's syndrome (Shoulder region)	0.000	0.491	0.509
M05.00 Felty's syndrome (Multiple sites)	0.000	0.491	0.509
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.491	0.509
M05.18 Rheumatoid lung disease (Other)	0.000	0.491	0.509
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.491	0.509
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.491	0.509
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.491	0.509
M05.14 Rheumatoid lung disease (Hand)	0.000	0.491	0.509
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.491	0.509
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.491	0.509
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.491	0.509
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.491	0.509
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.491	0.509
M05.28 Rheumatoid vasculitis (Other)	0.000	0.491	0.509
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.491	0.509
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.491	0.509
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.491	0.509
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.491	0.509
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.491	0.509
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.491	0.509
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.491	0.509
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.491	0.509
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.491	0.509
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.491	0.509
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.491	0.509
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.491	0.509
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.491	0.509
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.491	0.509
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.491	0.509
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.491	0.509
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.491	0.509
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.491	0.509
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.491	0.509
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.491	0.509
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.491	0.509
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.491	0.509
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.491	0.509
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.491	0.509
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.491	0.509
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.491	0.509
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.491	0.509
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.491	0.509
M12.2 Villonodular synovitis (pigmented)	0.000	0.491	0.509
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.000	0.494	0.506
M33 Dermatopolymyositis	0.000	0.496	0.504
M66.0 Rupture of popliteal cyst	0.000	0.496	0.504
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.499	0.501
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.499	0.501
M36.3 Arthropathy in other blood disorders	0.000	0.499	0.501
M36.2 Haemophilic arthropathy	0.000	0.499	0.501
M36.1 Arthropathy in neoplastic disease	0.000	0.499	0.501
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.499	0.501
E12.9 Without complications	0.000	0.501	0.499
E12.8 With unspecified complications	0.000	0.501	0.499
E12.7 With multiple complications	0.000	0.501	0.499
E12.6 With other specified complications	0.000	0.501	0.499
E12.5 With peripheral circulatory complications	0.000	0.501	0.499
E12.4 With neurological complications	0.000	0.501	0.499
E12.3 With ophthalmic complications	0.000	0.501	0.499
E12.2 With renal complications	0.000	0.501	0.499
E12.1 With ketoacidosis	0.000	0.501	0.499
E12.0 With coma	0.000	0.501	0.499
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.000	0.501	0.498
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.508	0.492
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.510	0.490
K90.9 Intestinal malabsorption, unspecified	0.000	0.512	0.488
M10.4 Other secondary gout	0.000	0.513	0.487
M10.3 Gout due to impairment of renal function	0.000	0.513	0.487
M10.2 Drug-induced gout	0.000	0.513	0.487
M10.1 Lead-induced gout	0.000	0.513	0.487
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.516	0.484
K90.3 Pancreatic steatorrhoea	0.000	0.519	0.481
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.519	0.481
K90.1 Tropical sprue	0.000	0.519	0.481
M49.8 Spondylopathy in other diseases classified elsewhere	0.000	0.520	0.479
M49.4 Neuropathic spondylopathy	0.000	0.520	0.479
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.000	0.520	0.479
M49.2 Enterobacterial spondylitis	0.000	0.520	0.479
M49.1 Brucella spondylitis	0.000	0.520	0.479
M49.0 Tuberculosis of spine	0.000	0.520	0.479
M22.8 Other disorders of patella	0.000	0.521	0.479
M46.8 Other specified inflammatory spondylopathies	0.000	0.525	0.475
M46.5 Other infective spondylopathies	0.000	0.525	0.475
M46.3 Infection of intervertebral disk (pyogenic)	0.000	0.525	0.475
M46.2 Osteomyelitis of vertebra	0.000	0.525	0.475
M46.0 Spinal enthesopathy	0.000	0.525	0.475
M46.1 Sacro-iliitis, not elsewhere classified	0.000	0.526	0.474
M62.86 Other specified disorders of muscle (Lower leg)	0.000	0.528	0.472
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.528	0.472
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.530	0.470
M13.0 Polyarthritis, unspecified	0.000	0.530	0.469
E20-E35 Disorders of other endocrine glands	0.000	0.531	0.469
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.532	0.468
M67 Other disorders of synovium and tendon	0.000	0.536	0.464
E65-E68 Obesity and other hyperalimentation	0.000	0.537	0.463
E16.1 Other hypoglycaemia	0.000	0.538	0.462
M31.8 Other specified necrotising vasculopathies	0.000	0.539	0.461
M31.7 Microscopic polyangiitis	0.000	0.539	0.461
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.539	0.461
M31.2 Lethal midline granuloma	0.000	0.539	0.461
M31.1 Thrombotic microangiopathy	0.000	0.539	0.461
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.543	0.457
E45 Retarded development following protein-energy malnutrition	0.000	0.543	0.457
E43 Unspecified severe protein-energy malnutrition	0.000	0.543	0.457
E42 Marasmic kwashiorkor	0.000	0.543	0.457
E41 Nutritional marasmus	0.000	0.543	0.457
E40 Kwashiorkor	0.000	0.543	0.457
M10.07 Idiopathic gout (Ankle and foot)	0.000	0.544	0.456
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.000	0.546	0.454
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.000	0.546	0.454
M02 Reactive arthropathies	0.000	0.546	0.454
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.000	0.546	0.454
L40-L45 Papulosquamous disorders	0.394	0.547	0.059
M62.84 Other specified disorders of muscle (Hand)	0.000	0.548	0.452
M49.5 Collapsed vertebra in diseases classified elsewhere	0.000	0.549	0.451
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.553	0.447
M91-M94 Chondropathies	0.000	0.553	0.447
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.553	0.447
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.554	0.446
M13.8 Other specified arthritis	0.000	0.556	0.444
E27 Other disorders of adrenal gland	0.000	0.559	0.441
M83 Adult osteomalacia	0.000	0.561	0.439
M40-M43 Deforming dorsopathies	0.000	0.562	0.437
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.564	0.436
M61.9 Calcification and ossification of muscle, unspecified	0.000	0.565	0.435
M61.5 Other ossification of muscle	0.000	0.565	0.435
M61.4 Other calcification of muscle	0.000	0.565	0.435
M61.3 Calcification and ossification of muscles associated with burns	0.000	0.565	0.435
M61.2 Paralytic calcification and ossification of muscle	0.000	0.565	0.435
M61.1 Myositis ossificans progressiva	0.000	0.565	0.435
M61.0 Myositis ossificans traumatica	0.000	0.565	0.435
M63.8 Other disorders of muscle in diseases classified elsewhere	0.000	0.565	0.435
M63.3 Myositis in sarcoidosis	0.000	0.565	0.435
M63.2 Myositis in other infectious diseases classified elsewhere	0.000	0.565	0.435
M63.1 Myositis in protozoal and parasitic infections classified elsewhere	0.000	0.565	0.435
M63.0 Myositis in bacterial diseases classified elsewhere	0.000	0.565	0.435
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.566	0.434
M31.0 Hypersensitivity angiitis	0.000	0.566	0.434
M66.5 Spontaneous rupture of unspecified tendon	0.000	0.566	0.434
M66.3 Spontaneous rupture of flexor tendons	0.000	0.566	0.434
M66.1 Rupture of synovium	0.000	0.566	0.434
M86 Osteomyelitis	0.000	0.566	0.434
M66.06 Rupture of popliteal cyst-Lower leg	0.000	0.568	0.432
E27.1 Primary adrenocortical insufficiency	0.000	0.568	0.432
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.000	0.570	0.430
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.214	0.572	0.214
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.214	0.572	0.214
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.214	0.572	0.214
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.214	0.572	0.214
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.214	0.572	0.214
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.214	0.572	0.214
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.214	0.572	0.214
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.214	0.572	0.214
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.214	0.572	0.214
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.214	0.572	0.214
M07.19 Arthritis mutilans (Site unspecified)	0.214	0.572	0.214
M07.18 Arthritis mutilans (Other)	0.214	0.572	0.214
M07.17 Arthritis mutilans (Ankle and foot)	0.214	0.572	0.214
M07.16 Arthritis mutilans (Lower leg)	0.214	0.572	0.214
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.214	0.572	0.214
M07.14 Arthritis mutilans (Hand)	0.214	0.572	0.214
M07.13 Arthritis mutilans (Forearm)	0.214	0.572	0.214
M07.12 Arthritis mutilans (Upper arm)	0.214	0.572	0.214
M07.11 Arthritis mutilans (Shoulder region)	0.214	0.572	0.214
M07.10 Arthritis mutilans (Multiple sites)	0.214	0.572	0.214
M07.29 Psoriatic spondylitis (Site unspecified)	0.214	0.572	0.214
M07.28 Psoriatic spondylitis (Other)	0.214	0.572	0.214
M07.27 Psoriatic spondylitis (Ankle and foot)	0.214	0.572	0.214
M07.26 Psoriatic spondylitis (Lower leg)	0.214	0.572	0.214
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.214	0.572	0.214
M07.24 Psoriatic spondylitis (Hand)	0.214	0.572	0.214
M07.23 Psoriatic spondylitis (Forearm)	0.214	0.572	0.214
M07.22 Psoriatic spondylitis (Upper arm)	0.214	0.572	0.214
M07.21 Psoriatic spondylitis (Shoulder region)	0.214	0.572	0.214
M07.20 Psoriatic spondylitis (Multiple sites)	0.214	0.572	0.214
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.214	0.572	0.214

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations