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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28383254
log Bayes Factor = 97.2454
Chromosome 6   position 32,585,638  (GRCh37) Explore rs28383254 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
M20-M25 Other joint disorders
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
J47 Bronchiectasis
0.000 0.000 1.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
J33.9 Nasal polyp, unspecified
0.000 0.002 0.998
J30-J39 Other diseases of upper respiratory tract
0.000 0.002 0.998
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.005 0.995
J20-J22 Other acute lower respiratory infections
0.000 0.007 0.993
M34 Systemic sclerosis
0.000 0.007 0.993
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.008 0.992
H02 Other disorders of eyelid
0.000 0.008 0.992
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.009 0.991
J84 Other interstitial pulmonary diseases
0.000 0.011 0.989
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.012 0.988
L20-L30 Dermatitis and eczema
0.000 0.013 0.987
J22 Unspecified acute lower respiratory infection
0.000 0.013 0.987
H04 Disorders of lachrymal system
0.000 0.015 0.985
J44 Other chronic obstructive pulmonary disease
0.000 0.022 0.978
H02.0 Entropion and trichiasis of eyelid
0.000 0.022 0.978
E10.4 With neurological complications
0.000 0.024 0.976
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.026 0.974
M34.9 Systemic sclerosis, unspecified
0.000 0.031 0.969
H02.1 Ectropion of eyelid
0.000 0.035 0.965
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.037 0.963
L40.0 Psoriasis vulgaris
0.960 0.040 0.000
J80 Adult respiratory distress syndrome
0.000 0.041 0.959
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.043 0.957
L30 Other dermatitis
0.000 0.043 0.957
M06.0 Seronegative rheumatoid arthritis
0.000 0.047 0.953
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.049 0.951
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.051 0.949
H55-H59 Other disorders of eye and adnexa
0.000 0.058 0.942
D69 Purpura and other haemorrhagic conditions
0.000 0.061 0.939
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.068 0.932
E20-E35 Disorders of other endocrine glands
0.000 0.073 0.927
E10.2 With renal complications
0.000 0.075 0.925
D68 Other coagulation defects
0.000 0.076 0.924
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.077 0.923
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.078 0.922
E04 Other non-toxic goitre
0.000 0.080 0.920
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.080 0.920
J32 Chronic sinusitis
0.000 0.081 0.919
E06 Thyroiditis
0.000 0.082 0.918
D50-D53 Nutritional anaemias
0.000 0.088 0.912
L29 Pruritus
0.000 0.088 0.912
L30.9 Dermatitis, unspecified
0.000 0.089 0.911
E10.5 With peripheral circulatory complications
0.000 0.091 0.909
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.093 0.907
E27 Other disorders of adrenal gland
0.000 0.093 0.907
H57 Other disorders of eye and adnexa
0.000 0.097 0.903
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.103 0.897
M34.1 CR(E)ST syndrome
0.000 0.105 0.895
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.105 0.895
E27.1 Primary adrenocortical insufficiency
0.000 0.105 0.895
M35.1 Other overlap syndromes
0.000 0.108 0.892
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.110 0.890
H16 Keratitis
0.000 0.112 0.888
M06.3 Rheumatoid nodule
0.000 0.114 0.886
E04.2 Non-toxic multinodular goitre
0.000 0.120 0.880
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.122 0.878
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.129 0.871
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.129 0.871
J33.8 Other polyp of sinus
0.000 0.130 0.870
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.133 0.867
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.135 0.865
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.137 0.863
H20 Iridocyclitis
0.000 0.138 0.862
E06.3 Autoimmune thyroiditis
0.000 0.141 0.859
L30.8 Other specified dermatitis
0.000 0.145 0.855
L29.0 Pruritus ani
0.000 0.147 0.853
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.152 0.848
H16.0 Corneal ulcer
0.000 0.153 0.847
D60-D64 Aplastic and other anaemias
0.000 0.155 0.845
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.156 0.844
D68.8 Other specified coagulation defects
0.000 0.163 0.837
L27 Dermatitis due to substances taken internally
0.000 0.166 0.834
M32 Systemic lupus erythematosus
0.000 0.168 0.832
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.168 0.832
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.171 0.829
M34.8 Other forms of systemic sclerosis
0.000 0.172 0.827
H57.0 Anomalies of pupillary function
0.000 0.174 0.826
N48 Other disorders of penis
0.825 0.175 0.000
L85 Other epidermal thickening
0.000 0.175 0.825
J00-J06 Acute upper respiratory infections
0.000 0.176 0.824
M06.4 Inflammatory polyarthropathy
0.000 0.178 0.822
H04.8 Other disorders of lachrymal system
0.000 0.179 0.821
D68.9 Coagulation defect, unspecified
0.000 0.179 0.821
N48.6 Balanitis xerotica obliterans
0.819 0.181 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.184 0.816
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.185 0.815
H05 Disorders of orbit
0.000 0.185 0.815
E10.8 With unspecified complications
0.000 0.186 0.814
D69.5 Secondary thrombocytopenia
0.000 0.189 0.811
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.191 0.809
D52 Folate deficiency anaemia
0.000 0.193 0.807
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.194 0.806
J32.0 Chronic maxillary sinusitis
0.000 0.196 0.804
L81 Other disorders of pigmentation
0.000 0.198 0.802
L21 Seborrhoeic dermatitis
0.000 0.199 0.801
J32.8 Other chronic sinusitis
0.000 0.200 0.800
D50 Iron deficiency anaemia
0.000 0.203 0.797
L40-L45 Papulosquamous disorders
0.564 0.204 0.231
L85.9 Epidermal thickening, unspecified
0.000 0.205 0.795
H57.8 Other specified disorders of eye and adnexa
0.000 0.207 0.793
E28 Ovarian dysfunction
0.000 0.209 0.791
D61 Other aplastic anaemias
0.000 0.213 0.787
H02.8 Other specified disorders of eyelid
0.000 0.213 0.787
E07 Other disorders of thyroid
0.000 0.213 0.786
J84.8 Other specified interstitial pulmonary diseases
0.000 0.217 0.783
N48.0 Leukoplakia of penis
0.783 0.217 0.000
M35.7 Hypermobility syndrome
0.000 0.217 0.782
E05.8 Other thyrotoxicosis
0.000 0.218 0.782
J81 Pulmonary oedema
0.000 0.219 0.781
H06.2 Dysthyroid exophthalmos
0.000 0.221 0.779
E16 Other disorders of pancreatic internal secretion
0.000 0.221 0.779
D69.0 Allergic purpura
0.000 0.223 0.777
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.229 0.771
L81.4 Other melanin hyperpigmentation
0.000 0.231 0.769
L29.2 Pruritus vulvae
0.000 0.233 0.767
J21 Acute bronchiolitis
0.000 0.234 0.766
M60-M63 Disorders of muscles
0.000 0.237 0.763
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.238 0.762
D68.5 Primary Thrombophilia
0.000 0.240 0.760
J95-J99 Other diseases of the respiratory system
0.000 0.240 0.760
H04.1 Other disorders of lachrymal gland
0.000 0.240 0.760
H55 Nystagmus and other irregular eye movements
0.000 0.240 0.760
D50.8 Other iron deficiency anaemias
0.000 0.240 0.760
J00 Acute nasopharyngitis [common cold]
0.000 0.241 0.759
L83 Acanthosis nigricans
0.000 0.242 0.758
J20 Acute bronchitis
0.000 0.244 0.756
E04.0 Non-toxic diffuse goitre
0.000 0.245 0.755
N48.8 Other specified disorders of penis
0.754 0.246 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.247 0.753
J32.9 Chronic sinusitis, unspecified
0.000 0.251 0.749
N48.9 Disorder of penis, unspecified
0.748 0.252 0.000
N48.4 Impotence of organic origin
0.747 0.253 0.000
H02.6 Xanthelasma of eyelid
0.000 0.254 0.746
M30 Polyarteritis nodosa and related conditions
0.000 0.255 0.745
D61.9 Aplastic anaemia, unspecified
0.000 0.256 0.744
L40.1 Generalised pustular psoriasis
0.742 0.257 0.000
E10.6 With other specified complications
0.000 0.258 0.741
H01 Other inflammation of eyelid
0.000 0.260 0.740
H57.9 Disorder of eye and adnexa, unspecified
0.000 0.262 0.738
D69.4 Other primary thrombocytopenia
0.000 0.262 0.738
L93 Lupus erythematosus
0.000 0.263 0.737
E16.2 Hypoglycaemia, unspecified
0.000 0.264 0.736
H04.4 Chronic inflammation of lachrymal passages
0.000 0.264 0.736
D68.0 Von Willebrand's disease
0.000 0.264 0.736
H20.8 Other iridocyclitis
0.000 0.265 0.735
L28 Lichen simplex chronicus and prurigo
0.000 0.266 0.734
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.268 0.732
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.268 0.732
D52.9 Folate deficiency anaemia, unspecified
0.000 0.269 0.731
L94 Other localised connective tissue disorders
0.000 0.269 0.731
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.274 0.726
H04.9 Disorder of lachrymal system, unspecified
0.000 0.277 0.723
E27.8 Other specified disorders of adrenal gland
0.000 0.278 0.722
H16.9 Keratitis, unspecified
0.000 0.280 0.720
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.8 Other specified systemic involvement of connective tissue
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
M35.2 Behcet's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H05.0 Acute inflammation of orbit
0.000 0.284 0.716
L20 Atopic dermatitis
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H20.9 Iridocyclitis, unspecified
0.000 0.287 0.713
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.288 0.712
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.288 0.712
M34.0 Progressive systemic sclerosis
0.000 0.288 0.712
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.289 0.711
J84.0 Alveolar and parietoalveolar conditions
0.000 0.291 0.709
L25 Unspecified contact dermatitis
0.000 0.292 0.708
L24 Irritant contact dermatitis
0.000 0.292 0.708
L26 Exfoliative dermatitis
0.000 0.292 0.708
L22 Diaper [napkin] dermatitis
0.000 0.292 0.708
H02.5 Other disorders affecting eyelid function
0.000 0.292 0.708
N48.1 Balanoposthitis
0.707 0.293 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.293 0.707
H04.6 Other changes in lachrymal passages
0.000 0.294 0.706
H04.0 Dacryoadenitis
0.000 0.294 0.706
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.294 0.706
M45-M49 Spondylopathies
0.001 0.295 0.703
L84 Corns and callosities
0.000 0.299 0.701
D62 Acute posthaemorrhagic anaemia
0.000 0.300 0.700
H30 Chorioretinal inflammation
0.000 0.300 0.700
E29 Testicular dysfunction
0.000 0.301 0.699
D67 Hereditary factor IX deficiency
0.000 0.301 0.699
H20.1 Chronic iridocyclitis
0.000 0.305 0.695
M45 Ankylosing spondylitis
0.001 0.305 0.694
M22 Disorders of patella
0.000 0.307 0.693
M12 Other specific arthropathies
0.000 0.309 0.691
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.000 0.310 0.690
M00-M03 Infectious arthropathies
0.000 0.314 0.686
L30.5 Pityriasis alba
0.000 0.314 0.686
L30.4 Erythema intertrigo
0.000 0.314 0.686
L30.2 Cutaneous autosensitisation
0.000 0.314 0.686
L30.1 Dyshidrosis [pompholyx]
0.000 0.314 0.686
L30.0 Nummular dermatitis
0.000 0.314 0.686
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.314 0.686
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.316 0.684
H02.2 Lagophthalmos
0.000 0.316 0.684
J01 Acute sinusitis
0.000 0.316 0.683
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.317 0.683
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.317 0.683
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.317 0.683
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.317 0.683
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.317 0.683
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.317 0.683
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.317 0.683
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.317 0.683
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.318 0.682
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.319 0.681
L57.0 Actinic keratosis
0.000 0.319 0.681
L10-L14 Bullous disorders
0.000 0.321 0.679
E20 Hypoparathyroidism
0.000 0.322 0.678
H31 Other disorders of choroid
0.000 0.323 0.677
D69.8 Other specified haemorrhagic conditions
0.000 0.326 0.673
D69.1 Qualitative platelet defects
0.000 0.326 0.673
L80 Vitiligo
0.000 0.328 0.672
L40.8 Other psoriasis
0.671 0.329 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.332 0.668
J32.1 Chronic frontal sinusitis
0.000 0.332 0.668
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.333 0.667
E26 Hyperaldosteronism
0.000 0.333 0.667
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.335 0.664
E32 Diseases of thymus
0.000 0.335 0.664
E31 Polyglandular dysfunction
0.000 0.335 0.664
E30 Disorders of puberty, not elsewhere classified
0.000 0.335 0.664
D68.4 Acquired coagulation factor deficiency
0.000 0.337 0.662
H15 Disorders of sclera
0.000 0.338 0.662
E04.8 Other specified non-toxic goitre
0.000 0.340 0.660
J32.3 Chronic sphenoidal sinusitis
0.000 0.341 0.659
N48.5 Ulcer of penis
0.659 0.341 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.342 0.658
E06.9 Thyroiditis, unspecified
0.000 0.342 0.658
E06.5 Other chronic thyroiditis
0.000 0.342 0.658
E06.4 Drug-induced thyroiditis
0.000 0.342 0.658
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.342 0.658
E06.1 Subacute thyroiditis
0.000 0.342 0.658
E06.0 Acute thyroiditis
0.000 0.342 0.658
L88 Pyoderma gangrenosum
0.000 0.343 0.657
M86-M90 Other osteopathies
0.000 0.345 0.655
L29.1 Pruritus scroti
0.000 0.346 0.654
L29.8 Other pruritus
0.000 0.347 0.653
E28.2 Polycystic ovarian syndrome
0.000 0.348 0.652
L58 Radiodermatitis
0.000 0.349 0.650
L55 Sunburn
0.000 0.349 0.650
E27.5 Adrenomedullary hyperfunction
0.000 0.350 0.650
E27.0 Other adrenocortical overactivity
0.000 0.350 0.650
J31.0 Chronic rhinitis
0.000 0.351 0.649
H53-H54 Visual disturbances and blindness
0.000 0.353 0.647
J60-J70 Lung diseases due to external agents
0.000 0.355 0.645
D53 Other nutritional anaemias
0.000 0.356 0.644
H40-H42 Glaucoma
0.000 0.358 0.642
J37 Chronic laryngitis and laryngotracheitis
0.000 0.358 0.642
D68.6 Other Thrombophilia
0.000 0.358 0.642
D80-D89 Certain disorders involving the immune mechanism
0.000 0.361 0.639
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.362 0.638
L87 Transepidermal elimination disorders
0.000 0.362 0.638
L86 Keratoderma in diseases classified elsewhere
0.000 0.362 0.638
E03.8 Other specified hypothyroidism
0.000 0.363 0.637
H16.8 Other keratitis
0.000 0.363 0.637
H16.4 Corneal neovascularisation
0.000 0.363 0.637
H16.3 Interstitial and deep keratitis
0.000 0.363 0.637
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.365 0.635
M06.38 Rheumatoid nodule (Other)
0.000 0.365 0.635
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.365 0.635
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.365 0.635
M06.33 Rheumatoid nodule (Forearm)
0.000 0.365 0.635
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.365 0.635
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.365 0.635
M21 Other acquired deformities of limbs
0.000 0.365 0.635
E22 Hyperfunction of pituitary gland
0.000 0.367 0.633
E28.3 Primary ovarian failure
0.000 0.367 0.633
E27.9 Disorder of adrenal gland, unspecified
0.000 0.367 0.633
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.368 0.632
D69.6 Thrombocytopenia, unspecified
0.000 0.368 0.632
H16.1 Other superficial keratitis without conjunctivitis
0.000 0.369 0.631
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.369 0.630
H01.8 Other specified inflammation of eyelid
0.000 0.370 0.630
H20.0 Acute and subacute iridocyclitis
0.000 0.370 0.630
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.371 0.629
J32.4 Chronic pansinusitis
0.000 0.371 0.628
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.371 0.628
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.373 0.627
L93.0 Discoid lupus erythematosus
0.000 0.373 0.627
D51 Vitamin B12 deficiency anaemia
0.000 0.373 0.627
H06.3 Other disorders of orbit in diseases classified elsewhere
0.000 0.375 0.625
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.000 0.375 0.625
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.000 0.375 0.625
E15 Nondiabetic hypoglycaemic coma
0.000 0.375 0.624
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.377 0.623
H05.2 Exophthalmic conditions
0.000 0.377 0.622
E07.9 Disorder of thyroid, unspecified
0.000 0.378 0.622
L95.8 Other vasculitis limited to skin
0.000 0.378 0.622
E50-E64 Other nutritional deficiencies
0.000 0.378 0.622
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.378 0.621
L23 Allergic contact dermatitis
0.000 0.378 0.621
L95.9 Vasculitis limited to skin, unspecified
0.000 0.379 0.621
M31 Other necrotising vasculopathies
0.000 0.379 0.621
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.380 0.620
L57.5 Actinic granuloma
0.000 0.380 0.620
L57.3 Poikiloderma of Civatte
0.000 0.380 0.620
L57.2 Cutis rhomboidalis nuchae
0.000 0.380 0.620
L57.1 Actinic reticuloid
0.000 0.380 0.620
H20.2 Lens-induced iridocyclitis
0.000 0.382 0.618
H10-H13 Disorders of conjunctiva
0.000 0.383 0.617
J31.2 Chronic pharyngitis
0.000 0.384 0.616
M11 Other crystal arthropathies
0.000 0.384 0.615
E14 Unspecified diabetes mellitus
0.000 0.386 0.614
L29.9 Pruritus, unspecified
0.000 0.388 0.612
H02.9 Disorder of eyelid, unspecified
0.000 0.388 0.612
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.388 0.612
M22.2 Patellofemoral disorders
0.000 0.389 0.611
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.390 0.610
D68.1 Hereditary factor XI deficiency
0.000 0.391 0.608
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.393 0.607
L94.0 Localised scleroderma [morphea]
0.000 0.393 0.607
H16.2 Keratoconjunctivitis
0.000 0.394 0.606
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.394 0.606
J04 Acute laryngitis and tracheitis
0.000 0.394 0.606
L30.3 Infective dermatitis
0.000 0.395 0.604
E40-E46 Malnutrition
0.000 0.396 0.604
J21.9 Acute bronchiolitis, unspecified
0.000 0.396 0.604
M14 Arthropathies in other diseases classified elsewhere
0.000 0.398 0.602
E34 Other endocrine disorders
0.000 0.399 0.601
L44 Other papulosquamous disorders
0.455 0.399 0.145
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.400 0.599
G35 Multiple sclerosis
0.000 0.401 0.599
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.402 0.598
L27.8 Dermatitis due to other substances taken internally
0.000 0.402 0.598
L27.2 Dermatitis due to ingested food
0.000 0.402 0.598
L98.4 Chronic ulcer of skin, not elsewhere classified
0.000 0.403 0.597
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.403 0.597
L08 Other local infections of skin and subcutaneous tissue
0.000 0.403 0.597
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.403 0.597
M32.8 Other forms of systemic lupus erythematosus
0.000 0.403 0.597
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.403 0.597
J20.9 Acute bronchitis, unspecified
0.000 0.404 0.596
H17 Corneal scars and opacities
0.000 0.406 0.594
E23.6 Other disorders of pituitary gland
0.000 0.407 0.593
N48.3 Priapism
0.592 0.408 0.000
L85.3 Xerosis cutis
0.000 0.408 0.592
L85.2 Keratosis punctata (palmaris et plantaris)
0.000 0.408 0.592
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.000 0.408 0.592
L85.0 Acquired ichthyosis
0.000 0.408 0.592
H02.4 Ptosis of eyelid
0.000 0.409 0.591
E23.2 Diabetes insipidus
0.000 0.409 0.591
L57.4 Cutis laxa senilis
0.000 0.409 0.590
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.410 0.590
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.410 0.590
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.410 0.590
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.410 0.590
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.410 0.590
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.410 0.590
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.410 0.590
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.410 0.590
M21.0 Valgus deformity, not elsewhere classified
0.000 0.411 0.589
J01.9 Acute sinusitis, unspecified
0.000 0.414 0.586
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.415 0.585
J42 Unspecified chronic bronchitis
0.000 0.415 0.585
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.000 0.416 0.584
H05.4 Enophthalmos
0.000 0.416 0.584
H05.3 Deformity of orbit
0.000 0.416 0.584
L28.1 Prurigo nodularis
0.000 0.416 0.584
E27.2 Addisonian crisis
0.000 0.418 0.582
L27.1 Localised skin eruption due to drugs and medicaments
0.000 0.420 0.580
J31.1 Chronic nasopharyngitis
0.000 0.420 0.580
E07.8 Other specified disorders of thyroid
0.000 0.421 0.579
D52.8 Other folate deficiency anaemias
0.000 0.421 0.578
D52.1 Drug-induced folate deficiency anaemia
0.000 0.421 0.578
D52.0 Dietary folate deficiency anaemia
0.000 0.421 0.578
L94.2 Calcinosis cutis
0.000 0.422 0.578
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.423 0.577
H00 Hordeolum and chalazion
0.000 0.424 0.576
L81.7 Pigmented purpuric dermatosis
0.000 0.425 0.575
L81.6 Other disorders of diminished melanin formation
0.000 0.425 0.575
L81.5 Leukoderma, not elsewhere classified
0.000 0.425 0.575
L81.3 Cafe au lait spots
0.000 0.425 0.575
L81.1 Chloasma
0.000 0.425 0.575
L81.0 Postinflammatory hyperpigmentation
0.000 0.425 0.575
M65-M68 Disorders of synovium and tendon
0.000 0.425 0.575
L21.8 Other seborrhoeic dermatitis
0.000 0.426 0.574
L21.1 Seborrhoeic infantile dermatitis
0.000 0.426 0.574
L21.0 Seborrhoea capitis
0.000 0.426 0.574
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.426 0.574
M60 Myositis
0.000 0.426 0.574
H18 Other disorders of cornea
0.000 0.426 0.574
J35 Chronic diseases of tonsils and adenoids
0.000 0.426 0.574
E65-E68 Obesity and other hyperalimentation
0.000 0.427 0.573
D61.1 Drug-induced aplastic anaemia
0.000 0.428 0.572
M40-M43 Deforming dorsopathies
0.000 0.428 0.572
H57.1 Ocular pain
0.000 0.428 0.572
D50.1 Sideropenic dysphagia
0.000 0.429 0.571
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.429 0.571
L41 Parapsoriasis
0.405 0.429 0.166
L45 Papulosquamous disorders in diseases classified elsewhere
0.405 0.429 0.166
H05.8 Other disorders of orbit
0.000 0.430 0.570
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.431 0.569
L42 Pityriasis rosea
0.422 0.431 0.148
N48.2 Other inflammatory disorders of penis
0.569 0.431 0.000
M62 Other disorders of muscle
0.000 0.431 0.568
J39 Other diseases of upper respiratory tract
0.000 0.433 0.567
E28.9 Ovarian dysfunction, unspecified
0.000 0.433 0.567
E28.8 Other ovarian dysfunction
0.000 0.433 0.567
E28.1 Androgen excess
0.000 0.433 0.567
E28.0 Oestrogen excess
0.000 0.433 0.567
E25 Adrenogenital disorders
0.000 0.434 0.566
L81.2 Freckles
0.000 0.435 0.564
D61.8 Other specified aplastic anaemias
0.000 0.435 0.564
D61.3 Idiopathic aplastic anaemia
0.000 0.435 0.564
D61.2 Aplastic anaemia due to other external agents
0.000 0.435 0.564
D61.0 Constitutional aplastic anaemia
0.000 0.435 0.564
E07.1 Dyshormogenetic goitre
0.000 0.436 0.564
E07.0 Hypersecretion of calcitonin
0.000 0.436 0.564
M30.0 Polyarteritis nodosa
0.000 0.437 0.563
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.441 0.559
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.441 0.559
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.000 0.441 0.558
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.442 0.558
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.442 0.558
E16.4 Abnormal secretion of gastrin
0.000 0.442 0.558

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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