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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28399637
log Bayes Factor = 12.56
Chromosome 19   position 45,324,138  (GRCh37) Explore rs28399637 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
F00-F09 Organic, including symptomatic, mental disorders
1.000 0.000 0.000
F03 Unspecified dementia
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
F00 Dementia in Alzheimer's disease
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
I22 Subsequent myocardial infarction
0.996 0.004 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.995 0.005 0.000
F01 Vascular dementia
0.995 0.005 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.993 0.007 0.000
F01.9 Vascular dementia, unspecified
0.991 0.009 0.000
I25.2 Old myocardial infarction
0.989 0.011 0.000
E78.0 Pure hypercholesterolaemia
0.974 0.026 0.000
I21 Acute myocardial infarction
0.961 0.039 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.942 0.058 0.000
I21.4 Acute subendocardial myocardial infarction
0.938 0.062 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.936 0.064 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.929 0.071 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.919 0.081 0.000
G30.9 Alzheimer's disease, unspecified
0.906 0.094 0.000
F02 Dementia in other diseases classified elsewhere
0.901 0.099 0.000
I25.5 Ischaemic cardiomyopathy
0.879 0.121 0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease
0.855 0.145 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.838 0.162 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.832 0.167 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.827 0.173 0.000
I23 Certain current complications following acute myocardial infarction
0.813 0.186 0.000
F05.1 Delirium superimposed on dementia
0.795 0.205 0.000
F01.1 Multi-infarct dementia
0.793 0.207 0.000
F05.8 Other delirium
0.792 0.208 0.000
F06.7 Mild cognitive disorder
0.778 0.222 0.000
F05.9 Delirium, unspecified
0.769 0.231 0.000
F09 Unspecified organic or symptomatic mental disorder
0.753 0.247 0.000
F06.2 Organic delusional [schizophrenia-like] disorder
0.734 0.266 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.733 0.267 0.000
G30 Alzheimer's disease
0.725 0.275 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.722 0.278 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
F01.8 Other vascular dementia
0.714 0.286 0.000
F01.3 Mixed cortical and subcortical vascular dementia
0.714 0.286 0.000
F01.2 Subcortical vascular dementia
0.714 0.286 0.000
F01.0 Vascular dementia of acute onset
0.714 0.286 0.000
I25.4 Coronary artery aneurysm
0.711 0.289 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.706 0.294 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.692 0.308 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.689 0.311 0.000
F05.0 Delirium not superimposed on dementia, so described
0.686 0.314 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.685 0.315 0.000
F02.0 Dementia in Pick's disease
0.684 0.316 0.000
I23.8 Other current complications following acute myocardial infarction
0.681 0.319 0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease
0.675 0.325 0.000
F06.6 Organic emotionally labile [asthenic] disorder
0.675 0.325 0.000
F06.5 Organic dissociative disorder
0.675 0.325 0.000
F06.4 Organic anxiety disorder
0.675 0.325 0.000
F06.3 Organic mood [affective] disorders
0.675 0.325 0.000
F06.1 Organic catatonic disorder
0.675 0.325 0.000
F06.0 Organic hallucinosis
0.675 0.325 0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease
0.646 0.354 0.000
F02.2 Dementia in Huntington's disease
0.646 0.354 0.000
F02.1 Dementia in Creutzfeldt-Jakob disease
0.646 0.354 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.620 0.380 0.000
I22.8 Subsequent myocardial infarction of other sites
0.620 0.380 0.000
G30.0 Alzheimer's disease with early onset
0.608 0.392 0.000
I25.3 Aneurysm of heart
0.594 0.406 0.000
F02.3 Dementia in Parkinson's disease
0.590 0.410 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.583 0.417 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.583 0.417 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.583 0.417 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.583 0.417 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.583 0.417 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.583 0.417 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.583 0.417 0.000
I24 Other acute ischaemic heart diseases
0.570 0.430 0.000
G30.1 Alzheimer's disease with late onset
0.540 0.460 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.526 0.473 0.001
G30-G32 Other degenerative diseases of the nervous system
0.506 0.494 0.000
I24.8 Other forms of acute ischaemic heart disease
0.492 0.508 0.000
G30.8 Other Alzheimer's disease
0.491 0.509 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.457 0.543 0.000
I20 Angina pectoris
0.450 0.550 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.397 0.603 0.000
G31.2 Degeneration of nervous system due to alcohol
0.395 0.605 0.000
I20.0 Unstable angina
0.393 0.607 0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction
0.377 0.622 0.001
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction
0.377 0.622 0.001
F07.1 Postencephalitic syndrome
0.377 0.622 0.001
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.376 0.624 0.000
I24.1 Dressler's syndrome
0.361 0.639 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.350 0.650 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.347 0.653 0.000
I20.9 Angina pectoris, unspecified
0.341 0.659 0.000
F07.0 Organic personality disorder
0.328 0.671 0.001
G31.1 Senile degeneration of brain, not elsewhere classified
0.328 0.672 0.000
G31.0 Circumscribed brain atrophy
0.326 0.674 0.000
E78.8 Other disorders of lipoprotein metabolism
0.301 0.699 0.000
G31.8 Other specified degenerative diseases of nervous system
0.301 0.699 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.301 0.699 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.283 0.717 0.000
E78.4 Other hyperlipidaemia
0.273 0.727 0.000
F07.2 Postconcussional syndrome
0.270 0.729 0.001
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.269 0.730 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.269 0.731 0.000
E78.3 Hyperchylomicronaemia
0.249 0.751 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.231 0.769 0.000
E78.2 Mixed hyperlipidaemia
0.220 0.780 0.000
E78.6 Lipoprotein deficiency
0.209 0.791 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.207 0.793 0.000
E78.5 Hyperlipidaemia, unspecified
0.177 0.823 0.000
E78.1 Pure hyperglyceridaemia
0.175 0.825 0.000
I20.8 Other forms of angina pectoris
0.110 0.890 0.000
Z95.1 Presence of aortocoronary bypass graft
0.095 0.905 0.000
I20.1 Angina pectoris with documented spasm
0.070 0.928 0.002
D18.0 Haemangioma, any site
0.066 0.934 0.000
I21.9 Acute myocardial infarction, unspecified
0.063 0.937 0.000
Chapter V Mental and behavioural disorders
0.054 0.946 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.052 0.948 0.000
F50 Eating disorders
0.050 0.950 0.000
E70-E90 Metabolic disorders
0.046 0.954 0.000
F50.0 Anorexia nervosa
0.046 0.954 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.046 0.954 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.045 0.955 0.000
T45.0 Antiallergic and antiemetic drugs
0.045 0.955 0.000
E89.2 Postprocedural hypoparathyroidism
0.045 0.955 0.000
Z95.3 Presence of xenogenic heart valve
0.044 0.956 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.044 0.956 0.000
F50.9 Eating disorder, unspecified
0.043 0.957 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.043 0.957 0.000
F51 Nonorganic sleep disorders
0.043 0.957 0.000
E89.3 Postprocedural hypopituitarism
0.043 0.957 0.000
Y84.0 Cardiac catheterisation
0.042 0.958 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.042 0.958 0.000
E85 Amyloidosis
0.041 0.959 0.000
E74 Other disorders of carbohydrate metabolism
0.040 0.960 0.000
T45.5 Anticoagulants
0.040 0.960 0.000
F99-F99 Unspecified mental disorder
0.039 0.961 0.000
F80-F89 Disorders of psychological development
0.039 0.961 0.000
F55 Abuse of non-dependence-producing substances
0.039 0.961 0.000
E84 Cystic fibrosis
0.038 0.961 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.038 0.962 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.037 0.963 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.037 0.963 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.037 0.963 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.037 0.963 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.037 0.963 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.036 0.964 0.000
F50.8 Other eating disorders
0.036 0.964 0.000
F50.5 Vomiting associated with other psychological disturbances
0.036 0.964 0.000
F50.4 Overeating associated with other psychological disturbances
0.036 0.964 0.000
F50.3 Atypical bulimia nervosa
0.036 0.964 0.000
F50.1 Atypical anorexia nervosa
0.036 0.964 0.000
F70-F79 Mental retardation
0.036 0.964 0.000
F51.5 Nightmares
0.036 0.964 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.035 0.964 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.035 0.965 0.000
F50.2 Bulimia nervosa
0.035 0.965 0.000
E85.4 Organ-limited amyloidosis
0.034 0.965 0.000
E89.4 Postprocedural ovarian failure
0.034 0.965 0.000
E85.8 Other amyloidosis
0.034 0.966 0.000
E70 Disorders of aromatic amino-acid metabolism
0.034 0.966 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.034 0.966 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.000 0.966 0.034
F60-F69 Disorders of adult personality and behaviour
0.034 0.966 0.000
E77 Disorders of glycoprotein metabolism
0.033 0.966 0.000
E76 Disorders of glycosaminoglycan metabolism
0.033 0.966 0.000
E72 Other disorders of amino-acid metabolism
0.033 0.966 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.033 0.966 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.033 0.966 0.000
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.033 0.966 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.033 0.967 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.033 0.967 0.000
E89.5 Postprocedural testicular hypofunction
0.033 0.967 0.000
E89.1 Postprocedural hypoinsulinaemia
0.033 0.967 0.000
F90 Hyperkinetic disorders
0.033 0.967 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.033 0.967 0.000
E85.3 Secondary systemic amyloidosis
0.032 0.968 0.000
F81 Specific developmental disorders of scholastic skills
0.032 0.968 0.000
F51.0 Nonorganic insomnia
0.032 0.968 0.000
E74.0 Glycogen storage disease
0.032 0.968 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.032 0.968 0.000
T45.2 Vitamins, not elsewhere classified
0.032 0.968 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.031 0.968 0.000
T45.8 Other primarily systemic and haematological agents
0.031 0.968 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.031 0.968 0.000
T45.6 Fibrinolysis-affecting drugs
0.031 0.968 0.000
T45.4 Iron and its compounds
0.031 0.968 0.000
T45.3 Enzymes, not elsewhere classified
0.031 0.968 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.031 0.969 0.000
F95 Tic disorders
0.031 0.969 0.000
F94 Disorders of social functioning with onset specific to childhood and adolescence
0.031 0.969 0.000
F93 Emotional disorders with onset specific to childhood
0.031 0.969 0.000
F92 Mixed disorders of conduct and emotions
0.031 0.969 0.000
F91 Conduct disorders
0.031 0.969 0.000
F51.9 Nonorganic sleep disorder, unspecified
0.031 0.969 0.000
F51.8 Other nonorganic sleep disorders
0.031 0.969 0.000
F51.4 Sleep terrors [night terrors]
0.031 0.969 0.000
F51.3 Sleepwalking [somnambulism]
0.031 0.969 0.000
F51.2 Nonorganic disorder of the sleep-wake schedule
0.031 0.969 0.000
F51.1 Nonorganic hypersomnia
0.031 0.969 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.030 0.970 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.030 0.970 0.000
E84.9 Cystic fibrosis, unspecified
0.030 0.970 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.030 0.970 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.029 0.970 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.029 0.970 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.029 0.970 0.000
E79 Disorders of purine and pyrimidine metabolism
0.029 0.971 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.029 0.971 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.029 0.971 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.029 0.971 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.029 0.971 0.000
E74.2 Disorders of galactose metabolism
0.029 0.971 0.000
E74.1 Disorders of fructose metabolism
0.029 0.971 0.000
F99 Mental disorder, not otherwise specified
0.029 0.971 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.028 0.972 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.028 0.972 0.000
F89 Unspecified disorder of psychological development
0.028 0.972 0.000
F88 Other disorders of psychological development
0.028 0.972 0.000
F83 Mixed specific developmental disorders
0.028 0.972 0.000
F82 Specific developmental disorder of motor function
0.028 0.972 0.000
E84.8 Cystic fibrosis with other manifestations
0.028 0.972 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.028 0.972 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.028 0.972 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.028 0.972 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.028 0.972 0.000
E75.5 Other lipid storage disorders
0.027 0.972 0.000
F84 Pervasive developmental disorders
0.027 0.972 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.027 0.973 0.000
F81.9 Developmental disorder of scholastic skills, unspecified
0.027 0.973 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.027 0.973 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.027 0.973 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.027 0.973 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.027 0.973 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.027 0.973 0.000
T44.0 Anticholinesterase agents
0.027 0.973 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.027 0.973 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.973 0.027
F53.9 Puerperal mental disorder, unspecified
0.027 0.973 0.000
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.027 0.973 0.000
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.027 0.973 0.000
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.027 0.973 0.000
F69 Unspecified disorder of adult personality and behaviour
0.027 0.973 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.027 0.973 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.027 0.973 0.000
F98.5 Stuttering [stammering]
0.027 0.973 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.026 0.973 0.000
D18 Haemangioma and lymphangioma, any site
0.026 0.973 0.000
F90.0 Disturbance of activity and attention
0.026 0.974 0.000
F78 Other mental retardation
0.026 0.974 0.000
F73 Profound mental retardation
0.026 0.974 0.000
F72 Severe mental retardation
0.026 0.974 0.000
F71 Moderate mental retardation
0.026 0.974 0.000
F70 Mild mental retardation
0.026 0.974 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.026 0.974 0.000
T36 Poisoning by systemic antibiotics
0.026 0.974 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.974 0.026
E75.6 Lipid storage disorder, unspecified
0.025 0.974 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.025 0.974 0.000
E75.3 Sphingolipidosis, unspecified
0.025 0.974 0.000
E75.2 Other sphingolipidosis
0.025 0.974 0.000
E75.1 Other gangliosidosis
0.025 0.974 0.000
E75.0 GM2 gangliosidosis
0.025 0.974 0.000
M16.0 Primary coxarthrosis, bilateral
0.000 0.974 0.026
E70.3 Albinism
0.025 0.975 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.025 0.975 0.000
F61 Mixed and other personality disorders
0.025 0.975 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.025 0.975 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.025 0.975 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.025 0.975 0.000
E70.2 Disorders of tyrosine metabolism
0.025 0.975 0.000
E70.1 Other hyperphenylalaninaemias
0.025 0.975 0.000
E70.0 Classical phenylketonuria
0.025 0.975 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.025 0.975 0.000
E85.9 Amyloidosis, unspecified
0.024 0.975 0.000
F68 Other disorders of adult personality and behaviour
0.024 0.975 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.024 0.975 0.000
F65 Disorders of sexual preference
0.024 0.975 0.000
F63 Habit and impulse disorders
0.024 0.975 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.024 0.975 0.000
E73 Lactose intolerance
0.024 0.975 0.000
L08 Other local infections of skin and subcutaneous tissue
0.000 0.976 0.024
E71.3 Disorders of fatty-acid metabolism
0.024 0.976 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.024 0.976 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.024 0.976 0.000
E71.0 Maple-syrup-urine disease
0.024 0.976 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.024 0.976 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.024 0.976 0.000
E72.5 Disorders of glycine metabolism
0.024 0.976 0.000
E72.4 Disorders of ornithine metabolism
0.024 0.976 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.024 0.976 0.000
E72.2 Disorders of urea cycle metabolism
0.024 0.976 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.024 0.976 0.000
E72.0 Disorders of amino-acid transport
0.024 0.976 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.024 0.976 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.024 0.976 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.024 0.976 0.000
E76.2 Other mucopolysaccharidoses
0.024 0.976 0.000
E76.1 Mucopolysaccharidosis, type II
0.024 0.976 0.000
E76.0 Mucopolysaccharidosis, type I
0.024 0.976 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.024 0.976 0.000
E77.8 Other disorders of glycoprotein metabolism
0.024 0.976 0.000
E77.1 Defects in glycoprotein degradation
0.024 0.976 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.024 0.976 0.000
F98.9 Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.024 0.976 0.000
F98.8 Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.024 0.976 0.000
F98.6 Cluttering
0.024 0.976 0.000
F98.4 Stereotyped movement disorders
0.024 0.976 0.000
F98.3 Pica of infancy and childhood
0.024 0.976 0.000
F98.2 Feeding disorder of infancy and childhood
0.024 0.976 0.000
F98.1 Nonorganic encopresis
0.024 0.976 0.000
F98.0 Nonorganic enuresis
0.024 0.976 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.024 0.976 0.000
F90.9 Hyperkinetic disorder, unspecified
0.024 0.976 0.000
F90.8 Other hyperkinetic disorders
0.024 0.976 0.000
F90.1 Hyperkinetic conduct disorder
0.024 0.976 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.024 0.976 0.000
F52.0 Lack or loss of sexual desire
0.023 0.976 0.000
F81.8 Other developmental disorders of scholastic skills
0.023 0.977 0.000
F81.3 Mixed disorder of scholastic skills
0.023 0.977 0.000
F81.2 Specific disorder of arithmetical skills
0.023 0.977 0.000
F81.1 Specific spelling disorder
0.023 0.977 0.000
F81.0 Specific reading disorder
0.023 0.977 0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease
0.023 0.977 0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease
0.023 0.977 0.000
F52.7 Excessive sexual drive
0.023 0.977 0.000
F52.6 Nonorganic dyspareunia
0.023 0.977 0.000
F52.5 Nonorganic vaginismus
0.023 0.977 0.000
F52.4 Premature ejaculation
0.023 0.977 0.000
F52.3 Orgasmic dysfunction
0.023 0.977 0.000
F52.1 Sexual aversion and lack of sexual enjoyment
0.023 0.977 0.000
E80.1 Porphyria cutanea tarda
0.023 0.977 0.000
T46.1 Calcium-channel blockers
0.023 0.977 0.000
F79 Unspecified mental retardation
0.022 0.977 0.000
F91.9 Conduct disorder, unspecified
0.022 0.977 0.000
F91.8 Other conduct disorders
0.022 0.977 0.000
F91.3 Oppositional defiant disorder
0.022 0.977 0.000
F91.2 Socialised conduct disorder
0.022 0.977 0.000
F91.1 Unsocialised conduct disorder
0.022 0.977 0.000
F91.0 Conduct disorder confined to the family context
0.022 0.977 0.000
F92.9 Mixed disorder of conduct and emotions, unspecified
0.022 0.977 0.000
F92.8 Other mixed disorders of conduct and emotions
0.022 0.977 0.000
F92.0 Depressive conduct disorder
0.022 0.977 0.000
F93.9 Childhood emotional disorder, unspecified
0.022 0.977 0.000
F93.8 Other childhood emotional disorders
0.022 0.977 0.000
F93.3 Sibling rivalry disorder
0.022 0.977 0.000
F93.2 Social anxiety disorder of childhood
0.022 0.977 0.000
F93.1 Phobic anxiety disorder of childhood
0.022 0.977 0.000
F93.0 Separation anxiety disorder of childhood
0.022 0.977 0.000
F94.9 Childhood disorder of social functioning, unspecified
0.022 0.977 0.000
F94.8 Other childhood disorders of social functioning
0.022 0.977 0.000
F94.2 Disinhibited attachment disorder of childhood
0.022 0.977 0.000
F94.1 Reactive attachment disorder of childhood
0.022 0.977 0.000
F94.0 Elective mutism
0.022 0.977 0.000
F95.9 Tic disorder, unspecified
0.022 0.977 0.000
F95.8 Other tic disorders
0.022 0.977 0.000
F95.2 Combined vocal and multiple motor tic disorder [de la Tourette]
0.022 0.977 0.000
F95.1 Chronic motor or vocal tic disorder
0.022 0.977 0.000
F95.0 Transient tic disorder
0.022 0.977 0.000
F80 Specific developmental disorders of speech and language
0.022 0.977 0.000
T50.4 Drugs affecting uric acid metabolism
0.022 0.978 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.022 0.978 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.022 0.978 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.022 0.978 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.022 0.978 0.000
T46.7 Peripheral vasodilators
0.022 0.978 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.022 0.978 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.022 0.978 0.000
T37.5 Antiviral drugs
0.022 0.978 0.000
T37.4 Anthelminthics
0.022 0.978 0.000
T37.3 Other antiprotozoal drugs
0.022 0.978 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.022 0.978 0.000
T37.1 Antimycobacterial drugs
0.022 0.978 0.000
T37.0 Sulphonamides
0.022 0.978 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.022 0.978 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.022 0.978 0.000
T42.3 Barbiturates
0.022 0.978 0.000
T42.2 Succinimides and oxazolidinediones
0.022 0.978 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.022 0.978 0.000
F84.0 Childhood autism
0.022 0.978 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.021 0.978 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.021 0.979 0.000
Z95.4 Presence of other heart-valve replacement
0.021 0.979 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.021 0.979 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.021 0.979 0.000
E79.1 Lesch-Nyhan syndrome
0.021 0.979 0.000
T47.0 Histamine H(2)-receptor antagonists
0.021 0.979 0.000
T40.2 Other opioids
0.021 0.979 0.000
T42.0 Hydantoin derivatives
0.021 0.979 0.000
T49.9 Topical agent, unspecified
0.020 0.979 0.000
T49.8 Other topical agents
0.020 0.979 0.000
T49.7 Dental drugs, topically applied
0.020 0.979 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.020 0.979 0.000
T49.5 Ophthalmological drugs and preparations
0.020 0.979 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.020 0.979 0.000
T49.3 Emollients, demulcents and protectants
0.020 0.979 0.000
T49.2 Local astringents and local detergents
0.020 0.979 0.000
T49.1 Antipruritics
0.020 0.979 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.020 0.979 0.000
T48.5 Anti-common-cold drugs
0.020 0.979 0.000
T48.4 Expectorants
0.020 0.979 0.000
T48.3 Antitussives
0.020 0.979 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.020 0.979 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.020 0.979 0.000
T48.0 Oxytocic drugs
0.020 0.979 0.000
Z95.2 Presence of prosthetic heart valve
0.020 0.980 0.000
F64 Gender identity disorders
0.020 0.980 0.000
T47.4 Other laxatives
0.020 0.980 0.000
T47.2 Stimulant laxatives
0.020 0.980 0.000
E80.6 Other disorders of bilirubin metabolism
0.020 0.980 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.020 0.980 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.020 0.980 0.000
E80.5 Crigler-Najjar syndrome
0.020 0.980 0.000
E80.3 Defects of catalase and peroxydase
0.020 0.980 0.000
E80.0 Hereditary erythropoietic porphyria
0.020 0.980 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.020 0.980 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.020 0.980 0.000
T47.7 Emetics
0.020 0.980 0.000
T47.6 Antidiarrhoeal drugs
0.020 0.980 0.000
T47.5 Digestants
0.020 0.980 0.000
T47.3 Saline and osmotic laxatives
0.020 0.980 0.000
E80.2 Other porphyria
0.020 0.980 0.000
F84.9 Pervasive developmental disorder, unspecified
0.020 0.980 0.000
F84.8 Other pervasive developmental disorders
0.020 0.980 0.000
F84.4 Overactive disorder associated with mental retardation and stereotyped movements
0.020 0.980 0.000
F84.3 Other childhood disintegrative disorder
0.020 0.980 0.000
F84.2 Rett's syndrome
0.020 0.980 0.000
F84.1 Atypical autism
0.020 0.980 0.000
F60 Specific personality disorders
0.020 0.980 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.020 0.980 0.000
T50.7 Analeptics and opioid receptor antagonists
0.019 0.980 0.000
T50.5 Appetite depressants
0.019 0.980 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.019 0.980 0.000
T50.1 Loop [high-ceiling] diuretics
0.019 0.980 0.000
T50.0 Mineralocorticoids and their antagonists
0.019 0.980 0.000
T41.5 Therapeutic gases
0.019 0.981 0.000
T41.4 Anaesthetic, unspecified
0.019 0.981 0.000
T41.3 Local anaesthetics
0.019 0.981 0.000
T41.2 Other and unspecified general anaesthetics
0.019 0.981 0.000
T41.1 Intravenous anaesthetics
0.019 0.981 0.000
T41.0 Inhaled anaesthetics
0.019 0.981 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.019 0.981 0.000
T42.1 Iminostilbenes
0.019 0.981 0.000
F70.9 Mild mental retardation (Without mention of impairment of behaviour)
0.019 0.981 0.000
F70.8 Mild mental retardation (Other impairments of behaviour)
0.019 0.981 0.000
F70.1 Mild mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.019 0.981 0.000
F70.0 Mild mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.019 0.981 0.000
F71.9 Moderate mental retardation (Without mention of impairment of behaviour)
0.019 0.981 0.000
F71.8 Moderate mental retardation (Other impairments of behaviour)
0.019 0.981 0.000
F71.1 Moderate mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.019 0.981 0.000
F71.0 Moderate mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.019 0.981 0.000
F72.9 Severe mental retardation (Without mention of impairment of behaviour)
0.019 0.981 0.000
F72.8 Severe mental retardation (Other impairments of behaviour)
0.019 0.981 0.000
F72.1 Severe mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.019 0.981 0.000
F72.0 Severe mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.019 0.981 0.000
F73.9 Profound mental retardation (Without mention of impairment of behaviour)
0.019 0.981 0.000
F73.8 Profound mental retardation (Other impairments of behaviour)
0.019 0.981 0.000
F73.1 Profound mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.019 0.981 0.000
F73.0 Profound mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.019 0.981 0.000
F78.9 Other mental retardation (Without mention of impairment of behaviour)
0.019 0.981 0.000
F78.8 Other mental retardation (Other impairments of behaviour)
0.019 0.981 0.000
F78.1 Other mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.019 0.981 0.000
F78.0 Other mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.019 0.981 0.000
T36.9 Systemic antibiotic, unspecified
0.018 0.981 0.000
T36.8 Other systemic antibiotics
0.018 0.981 0.000
T36.7 Antifungal antibiotics, systemically used
0.018 0.981 0.000
T36.6 Rifamycins
0.018 0.981 0.000
T36.5 Aminoglycosides
0.018 0.981 0.000
T36.4 Tetracyclines
0.018 0.981 0.000
T36.3 Macrolides
0.018 0.981 0.000
T36.2 Chloramphenicol group
0.018 0.981 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.018 0.981 0.000
D18.1 Lymphangioma, any site
0.018 0.981 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.018 0.981 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.018 0.982 0.000
L08.0 Pyoderma
0.000 0.982 0.018
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.018 0.982 0.000
T40.8 Lysergide [LSD]
0.018 0.982 0.000
T40.7 Cannabis (derivatives)
0.018 0.982 0.000
T40.3 Methadone
0.018 0.982 0.000
T40.1 Heroin
0.018 0.982 0.000
T40.0 Opium
0.018 0.982 0.000
F62.9 Enduring personality change, unspecified
0.018 0.982 0.000
F62.8 Other enduring personality changes
0.018 0.982 0.000
F62.1 Enduring personality change after psychiatric illness
0.018 0.982 0.000
F62.0 Enduring personality change after catastrophic experience
0.018 0.982 0.000
F63.9 Habit and impulse disorder, unspecified
0.018 0.982 0.000
F63.8 Other habit and impulse disorders
0.018 0.982 0.000
F63.3 Trichotillomania
0.018 0.982 0.000
F63.2 Pathological stealing [kleptomania]
0.018 0.982 0.000
F63.1 Pathological fire-setting [pyromania]
0.018 0.982 0.000
F63.0 Pathological gambling
0.018 0.982 0.000
F65.9 Disorder of sexual preference, unspecified
0.018 0.982 0.000
F65.8 Other disorders of sexual preference
0.018 0.982 0.000
F65.6 Multiple disorders of sexual preference
0.018 0.982 0.000
F65.5 Sadomasochism
0.018 0.982 0.000
F65.4 Paedophilia
0.018 0.982 0.000
F65.3 Voyeurism
0.018 0.982 0.000
F65.2 Exhibitionism
0.018 0.982 0.000
F65.1 Fetishistic transvestism
0.018 0.982 0.000
F65.0 Fetishism
0.018 0.982 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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