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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs284279
log Bayes Factor = 13.8688
Chromosome 1   position 10,789,697  (GRCh37) Explore rs284279 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
1.000 0.000 0.000
I10-I15 Hypertensive diseases
0.810 0.190 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.749 0.251 0.000
I71 Aortic aneurysm and dissection
0.749 0.251 0.000
I77.6 Arteritis, unspecified
0.746 0.254 0.000
Chapter IX Diseases of the circulatory system
0.741 0.259 0.000
I77 Other disorders of arteries and arterioles
0.736 0.264 0.000
I05-I09 Chronic rheumatic heart diseases
0.734 0.266 0.000
I08.0 Disorders of both mitral and aortic valves
0.732 0.268 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.726 0.274 0.000
I08 Multiple valve diseases
0.725 0.275 0.000
I71.0 Dissection of aorta [any part]
0.717 0.283 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.715 0.285 0.000
I11 Hypertensive heart disease
0.674 0.326 0.000
I07 Rheumatic tricuspid valve diseases
0.641 0.359 0.000
I70 Atherosclerosis
0.638 0.361 0.000
I13 Hypertensive heart and renal disease
0.630 0.370 0.000
I09 Other rheumatic heart diseases
0.594 0.406 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.588 0.412 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.580 0.420 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.579 0.421 0.000
I08.8 Other multiple valve diseases
0.578 0.422 0.000
I77.8 Other specified disorders of arteries and arterioles
0.576 0.424 0.000
I07.1 Tricuspid insufficiency
0.574 0.426 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.567 0.433 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.558 0.442 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.557 0.443 0.000
I78 Diseases of capillaries
0.545 0.455 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.537 0.463 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.537 0.463 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.533 0.467 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.533 0.467 0.000
I77.5 Necrosis of artery
0.528 0.472 0.000
I77.4 Coeliac artery compression syndrome
0.528 0.472 0.000
I77.3 Arterial fibromuscular dysplasia
0.528 0.472 0.000
I00-I02 Acute rheumatic fever
0.526 0.474 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.516 0.484 0.000
I77.2 Rupture of artery
0.514 0.486 0.000
I08.9 Multiple valve disease, unspecified
0.506 0.494 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.501 0.499 0.000
I09.9 Rheumatic heart disease, unspecified
0.494 0.506 0.000
I06 Rheumatic aortic valve diseases
0.491 0.509 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.477 0.523 0.000
I70.8 Atherosclerosis of other arteries
0.477 0.523 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.461 0.539 0.000
I07.9 Tricuspid valve disease, unspecified
0.459 0.540 0.000
I07.8 Other tricuspid valve diseases
0.459 0.540 0.000
I07.2 Tricuspid stenosis with insufficiency
0.459 0.540 0.000
I07.0 Tricuspid stenosis
0.459 0.540 0.000
I70.9 Generalised and unspecified atherosclerosis
0.458 0.542 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.452 0.548 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.452 0.548 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.452 0.548 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.445 0.555 0.000
I15 Secondary hypertension
0.438 0.561 0.000
I99 Other and unspecified disorders of circulatory system
0.438 0.562 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.436 0.564 0.000
I72 Other aneurysm
0.435 0.565 0.000
I09.8 Other specified rheumatic heart diseases
0.426 0.574 0.000
I09.2 Chronic rheumatic pericarditis
0.426 0.574 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.426 0.574 0.000
I09.0 Rheumatic myocarditis
0.426 0.574 0.000
I70.1 Atherosclerosis of renal artery
0.421 0.578 0.000
I78.8 Other diseases of capillaries
0.419 0.581 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.409 0.590 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.406 0.594 0.000
I79.1 Aortitis in diseases classified elsewhere
0.406 0.594 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.406 0.594 0.000
I77.0 Arteriovenous fistula, acquired
0.401 0.598 0.000
I72.9 Aneurysm of unspecified site
0.398 0.602 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.396 0.604 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.391 0.609 0.000
I78.9 Disease of capillaries, unspecified
0.390 0.609 0.000
I97.0 Postcardiotomy syndrome
0.382 0.618 0.000
I02 Rheumatic chorea
0.377 0.622 0.000
I01 Rheumatic fever with heart involvement
0.377 0.622 0.000
I70.0 Atherosclerosis of aorta
0.375 0.625 0.000
I00 Rheumatic fever without mention of heart involvement
0.372 0.628 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.361 0.639 0.000
I15.2 Hypertension secondary to endocrine disorders
0.359 0.641 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.352 0.647 0.000
I06.8 Other rheumatic aortic valve diseases
0.352 0.647 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.352 0.647 0.000
I06.1 Rheumatic aortic insufficiency
0.352 0.647 0.000
I05 Rheumatic mitral valve diseases
0.351 0.649 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.342 0.658 0.000
I72.4 Aneurysm of artery of lower extremity
0.329 0.671 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.328 0.671 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.328 0.671 0.000
I97.1 Other functional disturbances following cardiac surgery
0.320 0.680 0.000
I74 Arterial embolism and thrombosis
0.320 0.680 0.000
I06.0 Rheumatic aortic stenosis
0.317 0.682 0.000
I15.8 Other secondary hypertension
0.314 0.685 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.312 0.688 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.312 0.688 0.000
I72.1 Aneurysm of artery of upper extremity
0.312 0.688 0.000
I15.0 Renovascular hypertension
0.305 0.695 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.302 0.698 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.290 0.710 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.282 0.718 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.280 0.719 0.001
I72.2 Aneurysm of renal artery
0.280 0.720 0.000
I15.9 Seconday hypertension, unspecified
0.274 0.725 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.271 0.729 0.000
I01.8 Other acute rheumatic heart disease
0.271 0.729 0.000
I01.2 Acute rheumatic myocarditis
0.271 0.729 0.000
I01.1 Acute rheumatic endocarditis
0.271 0.729 0.000
I01.0 Acute rheumatic pericarditis
0.271 0.729 0.000
I02.9 Rheumatic chorea without heart involvement
0.271 0.729 0.000
I02.0 Rheumatic chorea with heart involvement
0.271 0.729 0.000
I74.5 Embolism and thrombosis of iliac artery
0.270 0.730 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.269 0.731 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.268 0.732 0.000
I78.1 Naevus, nonneoplastic
0.266 0.734 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.266 0.734 0.000
I05.8 Other mitral valve diseases
0.252 0.748 0.000
I05.1 Rheumatic mitral insufficiency
0.251 0.749 0.000
I05.0 Mitral stenosis
0.244 0.756 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.242 0.758 0.000
I05.2 Mitral stenosis with insufficiency
0.240 0.759 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.236 0.764 0.000
I72.3 Aneurysm of iliac artery
0.235 0.765 0.000
I72.0 Aneurysm of carotid artery
0.235 0.765 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.224 0.776 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.224 0.776 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.224 0.776 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.221 0.779 0.000
I12 Hypertensive renal disease
0.214 0.786 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.186 0.814 0.000
I28 Other diseases of pulmonary vessels
0.182 0.817 0.000
I72.8 Aneurysm of other specified arteries
0.176 0.824 0.000
I74.8 Embolism and thrombosis of other arteries
0.175 0.825 0.000
I77.1 Stricture of artery
0.174 0.826 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.169 0.831 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.169 0.831 0.000
I98.0 Cardiovascular syphilis
0.169 0.831 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.164 0.836 0.000
I73 Other peripheral vascular diseases
0.163 0.837 0.000
I27 Other pulmonary heart diseases
0.161 0.839 0.000
I15.1 Hypertension secondary to other renal disorders
0.147 0.852 0.001
I28.9 Disease of pulmonary vessels, unspecified
0.139 0.861 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.136 0.864 0.000
I27.8 Other specified pulmonary heart diseases
0.132 0.868 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.131 0.869 0.000
I28.1 Aneurysm of pulmonary artery
0.131 0.869 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.131 0.869 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.128 0.871 0.001
I73.1 Thromboangiitis obliterans [Buerger]
0.126 0.874 0.000
I05.9 Mitral valve disease, unspecified
0.126 0.874 0.000
I27.1 Kyphoscoliotic heart disease
0.116 0.884 0.000
I27.2 Other secondary pulmonary hypertension
0.113 0.887 0.000
I26 Pulmonary embolism
0.107 0.893 0.000
I73.8 Other specified peripheral vascular diseases
0.104 0.896 0.000
I28.8 Other specified diseases of pulmonary vessels
0.097 0.902 0.000
I27.9 Pulmonary heart disease, unspecified
0.098 0.902 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.081 0.918 0.000
I12.9 Hypertensive renal disease without renal failure
0.079 0.921 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.070 0.929 0.000
I27.0 Primary pulmonary hypertension
0.068 0.932 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.061 0.939 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.060 0.940 0.000
M80 Osteoporosis with pathological fracture
0.058 0.942 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.056 0.944 0.000
M85 Other disorders of bone density and structure
0.056 0.944 0.000
M80-M85 Disorders of bone density and structure
0.055 0.945 0.000
M85.8 Other specified disorders of bone density and structure
0.055 0.945 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.053 0.947 0.000
M84 Disorders of continuity of bone
0.051 0.949 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.049 0.951 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.049 0.951 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.049 0.951 0.000
M85.0 Fibrous dysplasia (monostotic)
0.048 0.952 0.000
N20.0 Calculus of kidney
0.047 0.953 0.000
N20 Calculus of kidney and ureter
0.046 0.954 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.046 0.954 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.045 0.955 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.045 0.955 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.044 0.956 0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.044 0.956 0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.044 0.956 0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.044 0.956 0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.044 0.956 0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.044 0.956 0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.044 0.956 0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.044 0.956 0.000
N20.1 Calculus of ureter
0.044 0.956 0.000
I73.0 Raynaud's syndrome
0.043 0.957 0.000
I95 Hypotension
0.043 0.957 0.000
M84.4 Pathological fracture, not elsewhere classified
0.043 0.957 0.000
M85.4 Solitary bone cyst
0.043 0.957 0.000
M82 Osteoporosis in diseases classified elsewhere
0.042 0.958 0.000
M83 Adult osteomalacia
0.042 0.958 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.042 0.958 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.042 0.958 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.042 0.958 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.041 0.958 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.041 0.958 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.041 0.958 0.000
N20.9 Urinary calculus, unspecified
0.041 0.959 0.000
M85.2 Hyperostosis of skull
0.040 0.959 0.000
M85.5 Aneurysmal bone cyst
0.040 0.960 0.000
M85.3 Osteitis condensans
0.040 0.960 0.000
M85.1 Skeletal fluorosis
0.040 0.960 0.000
N20.2 Calculus of kidney with calculus of ureter
0.040 0.960 0.000
M85.9 Disorder of bone density and structure, unspecified
0.040 0.960 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.040 0.960 0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)
0.040 0.960 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.040 0.960 0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)
0.040 0.960 0.000
M85.6 Other cyst of bone
0.040 0.960 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.040 0.960 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.040 0.960 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.040 0.960 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.039 0.961 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.039 0.961 0.000
M84.8 Other disorders of continuity of bone
0.038 0.961 0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.037 0.963 0.000
M84.3 Stress fracture, not elsewhere classified
0.037 0.963 0.000
M84.9 Disorder of continuity of bone, unspecified
0.037 0.963 0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)
0.036 0.964 0.000
M84.48 Pathological fracture, not elsewhere classified (Other)
0.036 0.964 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.036 0.964 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.036 0.964 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.036 0.964 0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)
0.035 0.965 0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)
0.035 0.965 0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)
0.035 0.965 0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)
0.035 0.965 0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)
0.035 0.965 0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)
0.035 0.965 0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)
0.035 0.965 0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)
0.035 0.965 0.000
M80.8 Other osteoporosis with pathological fracture
0.034 0.965 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.035 0.965 0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)
0.034 0.965 0.000
M85.08 Fibrous dysplasia (monostotic) (Other)
0.034 0.965 0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)
0.034 0.965 0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)
0.034 0.965 0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)
0.034 0.965 0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)
0.034 0.965 0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)
0.034 0.965 0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)
0.034 0.965 0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)
0.034 0.965 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.034 0.966 0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)
0.033 0.967 0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)
0.033 0.967 0.000
M82.1 Osteoporosis in endocrine disorders
0.033 0.967 0.000
M85.65 Other cyst of bone (Pelvic region and thigh)
0.033 0.967 0.000
M84.2 Delayed union of fracture
0.032 0.968 0.000
M83.3 Adult osteomalacia due to malnutrition
0.032 0.968 0.000
M83.8 Other adult osteomalacia
0.031 0.969 0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)
0.031 0.969 0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)
0.031 0.969 0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)
0.031 0.969 0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)
0.031 0.969 0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)
0.031 0.969 0.000
M85.49 Solitary bone cyst (Site unspecified)
0.031 0.969 0.000
M85.48 Solitary bone cyst (Other)
0.031 0.969 0.000
M85.47 Solitary bone cyst (Ankle and foot)
0.031 0.969 0.000
M85.46 Solitary bone cyst (Lower leg)
0.031 0.969 0.000
M85.44 Solitary bone cyst (Hand)
0.031 0.969 0.000
M85.43 Solitary bone cyst (Forearm)
0.031 0.969 0.000
M85.42 Solitary bone cyst (Upper arm)
0.031 0.969 0.000
M85.41 Solitary bone cyst (Shoulder region)
0.031 0.969 0.000
M85.40 Solitary bone cyst (Multiple sites)
0.031 0.969 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.031 0.969 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.030 0.969 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.030 0.969 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.030 0.969 0.000
M83.9 Adult osteomalacia, unspecified
0.030 0.969 0.000
M83.5 Other drug-induced osteomalacia in adults
0.030 0.969 0.000
M83.4 Aluminum bone disease
0.030 0.969 0.000
M83.2 Adult osteomalacia due to malabsorption
0.030 0.969 0.000
M83.1 Senile osteomalacia
0.030 0.969 0.000
M83.0 Puerperal osteomalacia
0.030 0.969 0.000
M85.64 Other cyst of bone (Hand)
0.030 0.970 0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)
0.030 0.970 0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)
0.030 0.970 0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)
0.030 0.970 0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)
0.030 0.970 0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)
0.030 0.970 0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)
0.030 0.970 0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)
0.030 0.970 0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)
0.030 0.970 0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)
0.030 0.970 0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)
0.030 0.970 0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)
0.030 0.970 0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)
0.030 0.970 0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)
0.030 0.970 0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)
0.030 0.970 0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)
0.030 0.970 0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)
0.030 0.970 0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)
0.030 0.970 0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)
0.030 0.970 0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)
0.030 0.970 0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)
0.030 0.970 0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)
0.030 0.970 0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)
0.030 0.970 0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)
0.030 0.970 0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)
0.030 0.970 0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)
0.030 0.970 0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)
0.030 0.970 0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)
0.030 0.970 0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)
0.030 0.970 0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)
0.030 0.970 0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)
0.030 0.970 0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)
0.030 0.970 0.000
M85.20 Hyperostosis of skull-Mult sites
0.029 0.970 0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)
0.029 0.971 0.000
M85.29 Hyperostosis of skull-Site unspec
0.029 0.971 0.000
M85.28 Hyperostosis of skull-Other
0.029 0.971 0.000
M85.27 Hyperostosis of skull-Ankle/Foot
0.029 0.971 0.000
M85.26 Hyperostosis of skull-Lower Leg
0.029 0.971 0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh
0.029 0.971 0.000
M85.24 Hyperostosis of skull-Hand
0.029 0.971 0.000
M85.23 Hyperostosis of skull-Forearm
0.029 0.971 0.000
M85.22 Hyperostosis of skull-Upper arm
0.029 0.971 0.000
M85.21 Hyperostosis of skull-Shldr region
0.029 0.971 0.000
M85.68 Other cyst of bone (Other)
0.029 0.971 0.000
M85.19 Skeletal fluorosis (Site unspecified)
0.029 0.971 0.000
M85.18 Skeletal fluorosis (Other)
0.029 0.971 0.000
M85.17 Skeletal fluorosis (Ankle and foot)
0.029 0.971 0.000
M85.16 Skeletal fluorosis (Lower leg)
0.029 0.971 0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)
0.029 0.971 0.000
M85.14 Skeletal fluorosis (Hand)
0.029 0.971 0.000
M85.13 Skeletal fluorosis (Forearm)
0.029 0.971 0.000
M85.12 Skeletal fluorosis (Upper arm)
0.029 0.971 0.000
M85.11 Skeletal fluorosis (Shoulder region)
0.029 0.971 0.000
M85.10 Skeletal fluorosis (Multiple sites)
0.029 0.971 0.000
M85.39 Osteitis condensans (Site unspecified)
0.029 0.971 0.000
M85.38 Osteitis condensans (Other)
0.029 0.971 0.000
M85.37 Osteitis condensans (Ankle and foot)
0.029 0.971 0.000
M85.36 Osteitis condensans (Lower leg)
0.029 0.971 0.000
M85.35 Osteitis condensans (Pelvic region and thigh)
0.029 0.971 0.000
M85.34 Osteitis condensans (Hand)
0.029 0.971 0.000
M85.33 Osteitis condensans (Forearm)
0.029 0.971 0.000
M85.32 Osteitis condensans (Upper arm)
0.029 0.971 0.000
M85.31 Osteitis condensans (Shoulder region)
0.029 0.971 0.000
M85.30 Osteitis condensans (Multiple sites)
0.029 0.971 0.000
M85.59 Aneurysmal bone cyst (Site unspecified)
0.029 0.971 0.000
M85.58 Aneurysmal bone cyst (Other)
0.029 0.971 0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)
0.029 0.971 0.000
M85.56 Aneurysmal bone cyst (Lower leg)
0.029 0.971 0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)
0.029 0.971 0.000
M85.54 Aneurysmal bone cyst (Hand)
0.029 0.971 0.000
M85.53 Aneurysmal bone cyst (Forearm)
0.029 0.971 0.000
M85.52 Aneurysmal bone cyst (Upper arm)
0.029 0.971 0.000
M85.51 Aneurysmal bone cyst (Shoulder region)
0.029 0.971 0.000
M85.50 Aneurysmal bone cyst (Multiple sites)
0.029 0.971 0.000
I95.2 Hypotension due to drugs
0.029 0.971 0.000
M85.98 Disorder of bone density and structure, unspecified (Other)
0.029 0.971 0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)
0.029 0.971 0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)
0.029 0.971 0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)
0.029 0.971 0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)
0.029 0.971 0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)
0.029 0.971 0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)
0.029 0.971 0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)
0.029 0.971 0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)
0.029 0.971 0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)
0.029 0.971 0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)
0.029 0.971 0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)
0.029 0.971 0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)
0.029 0.971 0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)
0.029 0.971 0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)
0.029 0.971 0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)
0.029 0.971 0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)
0.029 0.971 0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)
0.029 0.971 0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)
0.029 0.971 0.000
M85.69 Other cyst of bone (Site unspecified)
0.029 0.971 0.000
M85.63 Other cyst of bone (Forearm)
0.029 0.971 0.000
M85.62 Other cyst of bone (Upper arm)
0.029 0.971 0.000
M85.61 Other cyst of bone (Shoulder region)
0.029 0.971 0.000
M85.60 Other cyst of bone (Multiple sites)
0.029 0.971 0.000
M84.83 Other disorders of continuity of bone (Forearm)
0.028 0.972 0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)
0.028 0.972 0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)
0.028 0.972 0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)
0.028 0.972 0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)
0.028 0.972 0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)
0.028 0.972 0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)
0.028 0.972 0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)
0.028 0.972 0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)
0.028 0.972 0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)
0.028 0.972 0.000
M84.89 Other disorders of continuity of bone (Site unspecified)
0.028 0.972 0.000
M84.88 Other disorders of continuity of bone (Other)
0.028 0.972 0.000
M84.86 Other disorders of continuity of bone (Lower leg)
0.028 0.972 0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)
0.028 0.972 0.000
M84.84 Other disorders of continuity of bone (Hand)
0.028 0.972 0.000
M84.82 Other disorders of continuity of bone (Upper arm)
0.028 0.972 0.000
M84.81 Other disorders of continuity of bone (Shoulder region)
0.028 0.972 0.000
M84.80 Other disorders of continuity of bone (Multiple sites)
0.028 0.972 0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)
0.027 0.973 0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)
0.027 0.973 0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)
0.027 0.973 0.000
M84.38 Stress fracture, not elsewhere classified (Other)
0.027 0.973 0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)
0.027 0.973 0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)
0.027 0.973 0.000
M84.34 Stress fracture, not elsewhere classified (Hand)
0.027 0.973 0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)
0.027 0.973 0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)
0.027 0.973 0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)
0.027 0.973 0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)
0.027 0.973 0.000
I95.0 Idiopathic hypotension
0.027 0.973 0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)
0.026 0.973 0.000
M84.98 Disorder of continuity of bone, unspecified (Other)
0.026 0.973 0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)
0.026 0.973 0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)
0.026 0.973 0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)
0.026 0.973 0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)
0.026 0.973 0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)
0.026 0.973 0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)
0.026 0.973 0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)
0.026 0.973 0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)
0.026 0.973 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.026 0.974 0.000
M85.66 Other cyst of bone (Lower leg)
0.025 0.974 0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)
0.025 0.975 0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)
0.025 0.975 0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)
0.025 0.975 0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)
0.025 0.975 0.000
M80.84 Other osteoporosis with pathological fracture (Hand)
0.025 0.975 0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)
0.025 0.975 0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)
0.025 0.975 0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)
0.025 0.975 0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)
0.025 0.975 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.025 0.975 0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)
0.025 0.975 0.000
I20-I25 Ischaemic heart diseases
0.025 0.975 0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)
0.024 0.976 0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)
0.024 0.976 0.000
M82.18 Osteoporosis in endocrine disorders (Other)
0.024 0.976 0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)
0.024 0.976 0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)
0.024 0.976 0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)
0.024 0.976 0.000
M82.14 Osteoporosis in endocrine disorders (Hand)
0.024 0.976 0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)
0.024 0.976 0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)
0.024 0.976 0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.024 0.976 0.000
M83.80 Other adult osteomalacia (Multiple sites)
0.023 0.976 0.000
I95.8 Other hypotension
0.023 0.976 0.000
M84.29 Delayed union of fracture (Site unspecified)
0.023 0.977 0.000
M84.28 Delayed union of fracture (Other)
0.023 0.977 0.000
M84.27 Delayed union of fracture (Ankle and foot)
0.023 0.977 0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)
0.023 0.977 0.000
M84.24 Delayed union of fracture (Hand)
0.023 0.977 0.000
M84.23 Delayed union of fracture (Forearm)
0.023 0.977 0.000
M84.22 Delayed union of fracture (Upper arm)
0.023 0.977 0.000
M84.21 Delayed union of fracture (Shoulder region)
0.023 0.977 0.000
M84.20 Delayed union of fracture (Multiple sites)
0.023 0.977 0.000
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)
0.023 0.977 0.000
M83.38 Adult osteomalacia due to malnutrition (Other)
0.023 0.977 0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)
0.023 0.977 0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)
0.023 0.977 0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)
0.023 0.977 0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)
0.023 0.977 0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)
0.023 0.977 0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)
0.023 0.977 0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)
0.023 0.977 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.023 0.977 0.000
M83.89 Other adult osteomalacia (Site unspecified)
0.023 0.977 0.000
M83.88 Other adult osteomalacia (Other)
0.023 0.977 0.000
M83.87 Other adult osteomalacia (Ankle and foot)
0.023 0.977 0.000
M83.86 Other adult osteomalacia (Lower leg)
0.023 0.977 0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)
0.023 0.977 0.000
M83.84 Other adult osteomalacia (Hand)
0.023 0.977 0.000
M83.83 Other adult osteomalacia (Forearm)
0.023 0.977 0.000
M83.82 Other adult osteomalacia (Upper arm)
0.023 0.977 0.000
M83.81 Other adult osteomalacia (Shoulder region)
0.023 0.977 0.000
I12.0 Hypertensive renal disease with renal failure
0.022 0.978 0.000
M85.67 Other cyst of bone (Ankle and foot)
0.022 0.978 0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)
0.022 0.978 0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)
0.022 0.978 0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)
0.022 0.978 0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)
0.022 0.978 0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)
0.022 0.978 0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)
0.022 0.978 0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)
0.022 0.978 0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)
0.022 0.978 0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)
0.022 0.978 0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)
0.022 0.978 0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)
0.022 0.978 0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)
0.022 0.978 0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)
0.022 0.978 0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)
0.022 0.978 0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)
0.022 0.978 0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)
0.022 0.978 0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)
0.022 0.978 0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)
0.022 0.978 0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)
0.022 0.978 0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)
0.022 0.978 0.000
M83.09 Puerperal osteomalacia (Site unspecified)
0.022 0.978 0.000
M83.08 Puerperal osteomalacia (Other)
0.022 0.978 0.000
M83.07 Puerperal osteomalacia (Ankle and foot)
0.022 0.978 0.000
M83.06 Puerperal osteomalacia (Lower leg)
0.022 0.978 0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)
0.022 0.978 0.000
M83.04 Puerperal osteomalacia (Hand)
0.022 0.978 0.000
M83.03 Puerperal osteomalacia (Forearm)
0.022 0.978 0.000
M83.02 Puerperal osteomalacia (Upper arm)
0.022 0.978 0.000
M83.01 Puerperal osteomalacia (Shoulder region)
0.022 0.978 0.000
M83.00 Puerperal osteomalacia (Multiple sites)
0.022 0.978 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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