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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844498
log Bayes Factor = 60.031
Chromosome 6   position 31,476,854  (GRCh37) Explore rs2844498 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.004 0.996
E27 Other disorders of adrenal gland
0.000 0.009 0.991
E20-E35 Disorders of other endocrine glands
0.000 0.010 0.990
M45 Ankylosing spondylitis
0.990 0.010 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.012 0.988
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.982 0.018 0.000
R31 Unspecified haematuria
0.981 0.019 0.000
E10.1 With ketoacidosis
0.000 0.042 0.958
E06 Thyroiditis
0.000 0.045 0.955
E10.2 With renal complications
0.000 0.047 0.953
E06.3 Autoimmune thyroiditis
0.000 0.094 0.906
E27.8 Other specified disorders of adrenal gland
0.000 0.103 0.896
M45.X2 Ankylosing spondylitis (Cervical region)
0.895 0.105 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.111 0.889
E27.2 Addisonian crisis
0.000 0.116 0.884
K90 Intestinal malabsorption
0.000 0.132 0.868
G37 Other demyelinating diseases of central nervous system
0.000 0.134 0.866
E10.4 With neurological complications
0.000 0.137 0.863
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.150 0.850
E10.5 With peripheral circulatory complications
0.000 0.154 0.846
K90.9 Intestinal malabsorption, unspecified
0.000 0.160 0.840
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.160 0.840
E50-E64 Other nutritional deficiencies
0.000 0.162 0.838
E06.9 Thyroiditis, unspecified
0.000 0.172 0.828
E20 Hypoparathyroidism
0.000 0.175 0.825
E10.8 With unspecified complications
0.000 0.204 0.796
M45.X6 Ankylosing spondylitis (Lumbar region)
0.780 0.220 0.000
E14 Unspecified diabetes mellitus
0.000 0.220 0.780
E10.6 With other specified complications
0.000 0.223 0.777
E53 Deficiency of other B group vitamins
0.000 0.223 0.777
E40-E46 Malnutrition
0.000 0.237 0.763
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.242 0.758
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.244 0.756
E10.0 With coma
0.000 0.268 0.732
E25 Adrenogenital disorders
0.000 0.268 0.732
E31 Polyglandular dysfunction
0.000 0.270 0.730
E53.8 Deficiency of other specified B group vitamins
0.000 0.279 0.721
E10.7 With multiple complications
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.716
E27.5 Adrenomedullary hyperfunction
0.000 0.289 0.710
E27.0 Other adrenocortical overactivity
0.000 0.289 0.710
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.290 0.710
E32 Diseases of thymus
0.000 0.290 0.710
E30 Disorders of puberty, not elsewhere classified
0.000 0.290 0.710
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.710 0.290 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.710 0.290 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.710 0.290 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.710 0.290 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.710 0.290 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.710 0.290 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.294 0.706
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.301 0.699
E05.8 Other thyrotoxicosis
0.000 0.303 0.696
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.305 0.695
E06.4 Drug-induced thyroiditis
0.000 0.315 0.684
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.315 0.684
E06.0 Acute thyroiditis
0.000 0.315 0.684
E27.9 Disorder of adrenal gland, unspecified
0.000 0.322 0.678
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.330 0.670
E61 Deficiency of other nutrient elements
0.000 0.337 0.663
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.337 0.663
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.338 0.662
E14.3 With ophthalmic complications
0.000 0.342 0.658
E06.1 Subacute thyroiditis
0.000 0.343 0.657
E51 Thiamine deficiency
0.000 0.350 0.650
G36 Other acute disseminated demyelination
0.000 0.358 0.642
E34 Other endocrine disorders
0.000 0.358 0.642
E14.6 With other specified complications
0.000 0.375 0.625
K90.3 Pancreatic steatorrhoea
0.000 0.377 0.623
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.377 0.623
K90.1 Tropical sprue
0.000 0.377 0.623
G37.5 Concentric sclerosis [Balo]
0.000 0.379 0.621
G37.4 Subacute necrotising myelitis
0.000 0.379 0.621
G37.2 Central pontine myelinolysis
0.000 0.379 0.621
G37.1 Central demyelination of corpus callosum
0.000 0.379 0.621
G37.0 Diffuse sclerosis
0.000 0.379 0.621
E14.5 With peripheral circulatory complications
0.000 0.389 0.611
E06.5 Other chronic thyroiditis
0.000 0.390 0.609
E53.9 Vitamin B deficiency, unspecified
0.000 0.394 0.606
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.399 0.601
E63 Other nutritional deficiencies
0.000 0.399 0.601
E50 Vitamin A deficiency
0.000 0.399 0.601
E60 Dietary zinc deficiency
0.000 0.399 0.601
E59 Dietary selenium deficiency
0.000 0.399 0.601
E52 Niacin deficiency [pellagra]
0.000 0.399 0.601
E21.3 Hyperparathyroidism, unspecified
0.000 0.402 0.598
E14.1 With ketoacidosis
0.000 0.403 0.597
E26 Hyperaldosteronism
0.000 0.403 0.597
E14.2 Withrenal complications
0.000 0.403 0.597
E14.8 With unspecified complications
0.000 0.405 0.595
E46 Unspecified protein-energy malnutrition
0.000 0.407 0.593
E20.8 Other hypoparathyroidism
0.000 0.408 0.591
E20.1 Pseudohypoparathyroidism
0.000 0.408 0.591
E20.0 Idiopathic hypoparathyroidism
0.000 0.408 0.591
E56 Other vitamin deficiencies
0.000 0.409 0.591
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.416 0.584
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.423 0.577
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.428 0.572
K90.8 Other intestinal malabsorption
0.000 0.438 0.562
E14.7 With multiple complications
0.000 0.441 0.559
E14.0 With coma
0.000 0.441 0.559
E28 Ovarian dysfunction
0.000 0.441 0.559
E53.1 Pyridoxine deficiency
0.000 0.443 0.557
E53.0 Riboflavin deficiency
0.000 0.443 0.557
E61.1 Iron deficiency
0.000 0.443 0.557
E21.2 Other hyperparathyroidism
0.000 0.443 0.557
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.453 0.547
E45 Retarded development following protein-energy malnutrition
0.000 0.453 0.547
E43 Unspecified severe protein-energy malnutrition
0.000 0.453 0.547
E42 Marasmic kwashiorkor
0.000 0.453 0.547
E41 Nutritional marasmus
0.000 0.453 0.547
E40 Kwashiorkor
0.000 0.453 0.547
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.453 0.547
E21.4 Other specified disorders of parathyroid gland
0.000 0.455 0.544
E31.0 Autoimmune polyglandular failure
0.000 0.457 0.543
E24 Cushing's syndrome
0.000 0.460 0.540
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.468 0.532
E54 Ascorbic acid deficiency
0.000 0.470 0.530
E25.9 Adrenogenital disorder, unspecified
0.000 0.475 0.525
E25.8 Other adrenogenital disorders
0.000 0.475 0.525
E31.9 Polyglandular dysfunction, unspecified
0.000 0.476 0.523
E31.8 Other polyglandular dysfunction
0.000 0.476 0.523
E31.1 Polyglandular hyperfunction
0.000 0.476 0.523
E13 Other specified diabetes mellitus
0.001 0.483 0.517
E51.2 Wernicke's encephalopathy
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E23 Hypofunction and other disorders of pituitary gland
0.000 0.487 0.513
E30.9 Disorder of puberty, unspecified
0.000 0.491 0.509
E30.8 Other disorders of puberty
0.000 0.491 0.509
E30.1 Precocious puberty
0.000 0.491 0.509
E30.0 Delayed puberty
0.000 0.491 0.509
E32.9 Disease of thymus, unspecified
0.000 0.491 0.509
E32.8 Other diseases of thymus
0.000 0.491 0.509
E32.1 Abscess of thymus
0.000 0.491 0.509
E32.0 Persistent hyperplasia of thymus
0.000 0.491 0.509
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.491 0.509
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.491 0.509
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.491 0.509
E29 Testicular dysfunction
0.000 0.496 0.504
E14.4 With neurological complications
0.000 0.496 0.504
E58 Dietary calcium deficiency
0.000 0.500 0.500
E21.0 Primary hyperparathyroidism
0.000 0.509 0.491
E61.9 Deficiency of nutrient element, unspecified
0.000 0.524 0.475
E61.8 Deficiency of other specified nutrient elements
0.000 0.524 0.475
E61.7 Deficiency of multiple nutrient elements
0.000 0.524 0.475
E61.6 Vanadium deficiency
0.000 0.524 0.475
E61.5 Molybdenum deficiency
0.000 0.524 0.475
E61.4 Chromium deficiency
0.000 0.524 0.475
E61.3 Manganese deficiency
0.000 0.524 0.475
E61.0 Copper deficiency
0.000 0.524 0.475
E34.9 Endocrine disorder, unspecified
0.000 0.533 0.467
E51.9 Thiamine deficiency, unspecified
0.000 0.534 0.466
E51.8 Other manifestations of thiamine deficiency
0.000 0.534 0.466
E51.1 Beriberi
0.000 0.534 0.466
G36.0 Neuromyelitis optica [Devic]
0.000 0.535 0.465
E07 Other disorders of thyroid
0.000 0.537 0.463
G36.9 Acute disseminated demyelination, unspecified
0.000 0.539 0.460
G36.8 Other specified acute disseminated demyelination
0.000 0.539 0.460
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.539 0.460
E34.5 Androgen resistance syndrome
0.000 0.540 0.460
E34.4 Constitutional tall stature
0.000 0.540 0.460
E34.3 Short stature, not elsewhere classified
0.000 0.540 0.460
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.540 0.460
E34.1 Other hypersecretion of intestinal hormones
0.000 0.540 0.460
E34.8 Other specified endocrine disorders
0.000 0.553 0.446
E55 Vitamin D deficiency
0.000 0.554 0.446
E23.7 Disorder of pituitary gland, unspecified
0.000 0.556 0.444
E61.2 Magnesium deficiency
0.000 0.559 0.441
E65-E68 Obesity and other hyperalimentation
0.000 0.566 0.434
E50.9 Vitamin A deficiency, unspecified
0.000 0.569 0.431
E50.8 Other manifestations of vitamin A deficiency
0.000 0.569 0.431
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.569 0.431
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.569 0.431
E50.5 Vitamin A deficiency with night blindness
0.000 0.569 0.431
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.569 0.431
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.569 0.431
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.569 0.431
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.569 0.431
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.569 0.431
E63.9 Nutritional deficiency, unspecified
0.000 0.569 0.431
E63.8 Other specified nutritional deficiencies
0.000 0.569 0.431
E63.1 Imbalance of constituents of food intake
0.000 0.569 0.431
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.569 0.431
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.569 0.431
E64.8 Sequelae of other nutritional deficiencies
0.000 0.569 0.431
E64.3 Sequelae of rickets
0.000 0.569 0.431
E64.2 Sequelae of vitamin C deficiency
0.000 0.569 0.431
E64.1 Sequelae of vitamin A deficiency
0.000 0.569 0.431
E64.0 Sequelae of protein-energy malnutrition
0.000 0.569 0.431
E26.8 Other hyperaldosteronism
0.000 0.572 0.428
E26.1 Secondary hyperaldosteronism
0.000 0.572 0.428
E11 Non-insulin-dependent diabetes mellitus
0.000 0.572 0.428
E56.9 Vitamin deficiency, unspecified
0.000 0.576 0.424
E56.8 Deficiency of other vitamins
0.000 0.576 0.424
E56.0 Deficiency of vitamin E
0.000 0.576 0.424
E26.9 Hyperaldosteronism, unspecified
0.000 0.578 0.422
E56.1 Deficiency of vitamin K
0.000 0.586 0.414
E15 Nondiabetic hypoglycaemic coma
0.000 0.590 0.410
E28.9 Ovarian dysfunction, unspecified
0.000 0.599 0.401
E28.8 Other ovarian dysfunction
0.000 0.599 0.401
E28.1 Androgen excess
0.000 0.599 0.401
E28.0 Oestrogen excess
0.000 0.599 0.401
E34.0 Carcinoid syndrome
0.000 0.600 0.400
E13.3 With ophthalmic complications
0.001 0.605 0.394
E44.1 Mild protein-energy malnutrition
0.000 0.608 0.392
E44.0 Moderate protein-energy malnutrition
0.000 0.608 0.392
E11.5 With peripheral circulatory complications
0.000 0.609 0.391
E24.8 Other Cushing's syndrome
0.000 0.612 0.387
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.612 0.387
E24.3 Ectopic ACTH syndrome
0.000 0.612 0.387
E24.1 Nelson's syndrome
0.000 0.612 0.387
E28.3 Primary ovarian failure
0.000 0.614 0.386
E13.8 With unspecified complications
0.001 0.629 0.371
E13.7 With multiple complications
0.001 0.629 0.371
E13.6 With other specified complications
0.001 0.629 0.371
E13.5 With peripheral circulatory complications
0.001 0.629 0.371
E13.4 With neurological complications
0.001 0.629 0.371
E13.2 With renal complications
0.001 0.629 0.371
E13.1 With ketoacidosis
0.001 0.629 0.371
E13.0 With coma
0.001 0.629 0.371
E11.3 With ophthalmic complications
0.000 0.630 0.370
E24.0 Pituitary-dependent Cushing's disease
0.000 0.630 0.369
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.632 0.368
E23.1 Drug-induced hypopituitarism
0.000 0.632 0.368
E29.9 Testicular dysfunction, unspecified
0.000 0.638 0.361
E29.8 Other testicular dysfunction
0.000 0.638 0.361
E29.0 Testicular hyperfunction
0.000 0.638 0.361
E11.8 With unspecified complications
0.000 0.650 0.350
E24.2 Drug-induced Cushing's syndrome
0.000 0.654 0.346
E22 Hyperfunction of pituitary gland
0.000 0.654 0.346
R30.0 Dysuria
0.338 0.662 0.000
E07.1 Dyshormogenetic goitre
0.000 0.668 0.332
E07.0 Hypersecretion of calcitonin
0.000 0.668 0.332
E26.0 Primary hyperaldosteronism
0.000 0.675 0.325
R30 Pain associated with micturition
0.325 0.675 0.000
R30-R39 Symptoms and signs involving the urinary system
0.324 0.676 0.000
E55.0 Rickets, active
0.000 0.680 0.320
E24.9 Cushing's syndrome, unspecified
0.000 0.687 0.313
E67 Other hyperalimentation
0.000 0.689 0.311
E68 Sequelae of hyperalimentation
0.000 0.689 0.311
E07.8 Other specified disorders of thyroid
0.000 0.689 0.311
E11.1 With ketoacidosis
0.000 0.689 0.311
E23.2 Diabetes insipidus
0.000 0.696 0.304
E11.7 With multiple complications
0.000 0.710 0.289
E03 Other hypothyroidism
0.000 0.714 0.286
E23.6 Other disorders of pituitary gland
0.000 0.722 0.278
E28.2 Polycystic ovarian syndrome
0.000 0.724 0.275
R34 Anuria and oliguria
0.273 0.727 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.734 0.266
E11.2 With renal complications
0.000 0.737 0.263
E65 Localised adiposity
0.000 0.739 0.261
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.752 0.248
E22.8 Other hyperfunction of pituitary gland
0.000 0.752 0.248
E11.6 With other specified complications
0.000 0.756 0.244
R36 Urethral discharge
0.241 0.759 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.763 0.236
E04 Other non-toxic goitre
0.000 0.768 0.232
E67.8 Other specified hyperalimentation
0.000 0.777 0.223
E67.3 Hypervitaminosis D
0.000 0.777 0.223
E67.2 Megavitamin-B6 syndrome
0.000 0.777 0.223
E67.1 Hypercarotenaemia
0.000 0.777 0.223
E67.0 Hypervitaminosis A
0.000 0.777 0.223
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.780 0.220
R30.1 Vesical tenesmus
0.219 0.781 0.000
E11.0 With coma
0.000 0.791 0.208
E03.5 Myxoedema coma
0.000 0.794 0.205
E03.4 Atrophy of thyroid (acquired)
0.000 0.794 0.205
E03.3 Postinfectious hypothyroidism
0.000 0.794 0.205
E04.0 Non-toxic diffuse goitre
0.000 0.795 0.205
E23.0 Hypopituitarism
0.000 0.795 0.205
E03.8 Other specified hypothyroidism
0.000 0.806 0.194
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.809 0.191
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.809 0.191
E16.4 Abnormal secretion of gastrin
0.000 0.809 0.191
E16.3 Increased secretion of glucagon
0.000 0.809 0.191
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.816 0.184
E22.1 Hyperprolactinaemia
0.001 0.822 0.177
E03.1 Congenital hypothyroidism without goitre
0.000 0.825 0.175
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.826 0.174
E04.8 Other specified non-toxic goitre
0.000 0.834 0.166
E55.9 Vitamin D deficiency, unspecified
0.000 0.836 0.164
E29.1 Testicular hypofunction
0.001 0.844 0.155
E16.2 Hypoglycaemia, unspecified
0.000 0.845 0.155
E66 Obesity
0.000 0.854 0.146
E07.9 Disorder of thyroid, unspecified
0.000 0.868 0.132
E16.1 Other hypoglycaemia
0.001 0.870 0.129
E66.8 Other obesity
0.000 0.878 0.122
R35 Polyuria
0.119 0.881 0.000
E11.4 With neurological complications
0.000 0.884 0.116
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.001 0.894 0.106
E13.9 Without complications
0.002 0.894 0.104
E66.1 Drug-induced obesity
0.000 0.895 0.105
R30.9 Painful micturition, unspecified
0.099 0.900 0.001
K90-K93 Other diseases of the digestive system
0.000 0.907 0.093
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.915 0.085
E66.0 Obesity due to excess calories
0.000 0.923 0.077
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.933 0.067
E04.2 Non-toxic multinodular goitre
0.000 0.934 0.066
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.940 0.060
R39 Other symptoms and signs involving the urinary system
0.059 0.941 0.000
M45-M49 Spondylopathies
0.053 0.947 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.947 0.052
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.952 0.048
K93.1 Megacolon in Chagas' disease
0.000 0.952 0.048
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.952 0.048
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.953 0.047
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.957 0.043
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.958 0.042
R39.2 Extrarenal uraemia
0.042 0.958 0.000
D69 Purpura and other haemorrhagic conditions
0.000 0.959 0.041
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.961 0.039
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.961 0.039
E04.9 Non-toxic goitre, unspecified
0.000 0.962 0.038
E14.9 Without complications
0.000 0.964 0.036
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.965 0.035
D69.4 Other primary thrombocytopenia
0.000 0.965 0.035
K91.5 Postcholecystectomy syndrome
0.000 0.965 0.035
D69.2 Other nonthrombocytopenic purpura
0.000 0.965 0.035
R39.0 Extravasation of urine
0.035 0.965 0.000
D69.5 Secondary thrombocytopenia
0.000 0.965 0.035
K91.1 Postgastric surgery syndromes
0.000 0.966 0.034
M49 Spondylopathies in diseases classified elsewhere
0.033 0.967 0.000
D68 Other coagulation defects
0.000 0.968 0.032
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.969 0.031
C91 Lymphoid leukaemia
0.000 0.970 0.030
C91.1 Chronic lymphocytic leukaemia
0.000 0.970 0.030
D69.8 Other specified haemorrhagic conditions
0.000 0.970 0.029
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.971 0.029
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.971 0.029
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.972 0.028
M35.0 Sicca syndrome [Sjogren]
0.000 0.972 0.028
D69.1 Qualitative platelet defects
0.000 0.972 0.028
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.972 0.028
D69.6 Thrombocytopenia, unspecified
0.000 0.972 0.028
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.972 0.028
D68.6 Other Thrombophilia
0.000 0.972 0.028
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.972 0.028
S02.4 Fracture of malar and maxillary bones
0.000 0.972 0.027
D69.0 Allergic purpura
0.000 0.973 0.027
D55-D59 Haemolytic anaemias
0.000 0.973 0.027
D80-D89 Certain disorders involving the immune mechanism
0.000 0.973 0.027
D59 Acquired haemolytic anaemia
0.000 0.973 0.027
D69.9 Haemorrhagic condition, unspecified
0.000 0.973 0.026
D68.9 Coagulation defect, unspecified
0.000 0.973 0.027
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.974 0.026
E11.9 Without complications
0.000 0.974 0.026
J03.9 Acute tonsillitis, unspecified
0.026 0.974 0.000
C91.9 Lymphoid leukaemia, unspecified
0.000 0.974 0.026
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.975 0.025
D66 Hereditary factor VIII deficiency
0.000 0.975 0.025
C81 Hodgkin's disease
0.000 0.975 0.025
J92.9 Pleural plaque without asbestos
0.025 0.975 0.000
M46 Other inflammatory spondylopathies
0.025 0.975 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.975 0.025
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.975 0.025
D68.1 Hereditary factor XI deficiency
0.000 0.975 0.024
D86 Sarcoidosis
0.000 0.975 0.025
C91.4 Hairy-cell leukaemia
0.000 0.976 0.024
C84.5 Other and unspecified T-cell lymphomas
0.000 0.976 0.024
M49.8 Spondylopathy in other diseases classified elsewhere
0.024 0.976 0.000
M49.4 Neuropathic spondylopathy
0.024 0.976 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.024 0.976 0.000
M49.2 Enterobacterial spondylitis
0.024 0.976 0.000
M49.1 Brucella spondylitis
0.024 0.976 0.000
M49.0 Tuberculosis of spine
0.024 0.976 0.000
D68.2 Hereditary deficiency of other clotting factors
0.000 0.976 0.024
D59.1 Other autoimmune haemolytic anaemias
0.000 0.977 0.023
D67 Hereditary factor IX deficiency
0.000 0.977 0.023
C91.0 Acute lymphoblastic leukaemia
0.000 0.977 0.023
C91.5 Adult T-cell leukaemia
0.000 0.977 0.022
D56 Thalassaemia
0.000 0.977 0.022
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.978 0.022
C84.4 Peripheral T-cell lymphoma
0.000 0.978 0.022
D84 Other immunodeficiencies
0.000 0.978 0.022
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.978 0.022
C91.7 Other lymphoid leukaemia
0.000 0.978 0.022
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.978 0.022
C91.3 Prolymphocytic leukaemia
0.000 0.978 0.022
C91.2 Subacute lymphocytic leukaemia
0.000 0.978 0.022
D82 Immunodeficiency associated with other major defects
0.000 0.978 0.022
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.979 0.021
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.979 0.021
D68.0 Von Willebrand's disease
0.000 0.979 0.021
D80 Immunodeficiency with predominantly antibody defects
0.000 0.979 0.021
C81.1 Nodular sclerosis
0.000 0.979 0.021
M47 Spondylosis
0.021 0.979 0.000
C83.0 Small cell (diffuse)
0.000 0.979 0.021
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.979 0.021
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.979 0.021
C85.0 Lymphosarcoma
0.000 0.979 0.021
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.979 0.021
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.980 0.020
C94 Other leukaemias of specified cell type
0.000 0.980 0.020
D57 Sickle-cell disorders
0.000 0.980 0.020
C93 Monocytic leukaemia
0.000 0.980 0.020
D68.4 Acquired coagulation factor deficiency
0.000 0.980 0.020
D68.8 Other specified coagulation defects
0.000 0.980 0.020
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.980 0.020
D55 Anaemia due to enzyme disorders
0.000 0.980 0.020
C86 Other specified types of T/NK-cell lymphoma
0.000 0.980 0.020
D81 Combined immunodeficiencies
0.000 0.980 0.020
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.020 0.980 0.000
C95 Leukaemia of unspecified cell type
0.000 0.980 0.020
D59.8 Other acquired haemolytic anaemias
0.000 0.980 0.019
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.980 0.019
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.980 0.019
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.980 0.019
D59.3 Haemolytic-uraemic syndrome
0.000 0.980 0.019
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.980 0.019
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.980 0.019
D60-D64 Aplastic and other anaemias
0.000 0.980 0.020
C81.0 Lymphocytic predominance
0.000 0.981 0.019
D86.3 Sarcoidosis of skin
0.000 0.981 0.019
K91.3 Postoperative intestinal obstruction
0.000 0.981 0.019
C90.2 Plasmacytoma, extramedullary
0.000 0.981 0.019
C81.9 Hodgkin's disease, unspecified
0.000 0.981 0.019
D61 Other aplastic anaemias
0.000 0.981 0.019
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.981 0.019
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.981 0.019
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.981 0.019
C84.3 Lymphoepithelioid lymphoma
0.000 0.981 0.019
C84.2 T-zone lymphoma
0.000 0.981 0.019
C84.1 Sezary's diease
0.000 0.981 0.019
M49.5 Collapsed vertebra in diseases classified elsewhere
0.019 0.981 0.000
C88 Malignant immunoproliferative diseases
0.000 0.981 0.019
M46.3 Infection of intervertebral disk (pyogenic)
0.019 0.981 0.000
F52.2 Failure of genital response
0.019 0.981 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.019 0.981 0.000
D61.9 Aplastic anaemia, unspecified
0.000 0.981 0.019
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.981 0.019
C81.7 Other Hodgkin's disease
0.000 0.981 0.019
C81.2 Mixed cellularity
0.000 0.981 0.019
D83 Common variable immunodeficiency
0.000 0.981 0.018
D56.3 Thalassaemia trait
0.000 0.982 0.018
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.982 0.018
D86.1 Sarcoidosis of lymph nodes
0.000 0.982 0.018
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.982 0.018
C81.3 Lymphocytic depletion
0.000 0.982 0.018
D84.1 Defects in the complement system
0.000 0.982 0.018
M46.8 Other specified inflammatory spondylopathies
0.018 0.982 0.000
M46.5 Other infective spondylopathies
0.018 0.982 0.000
M46.2 Osteomyelitis of vertebra
0.018 0.982 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.982 0.018
D82.1 Di George's syndrome
0.000 0.982 0.018
M48 Other spondylopathies
0.018 0.982 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.982 0.018
M49.09 Tuberculosis of spine (Site unspecified)
0.017 0.982 0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.017 0.982 0.000
M49.07 Tuberculosis of spine (Lumbosacral region)
0.017 0.982 0.000
M49.06 Tuberculosis of spine (Lumbar region)
0.017 0.982 0.000
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.017 0.982 0.000
M49.04 Tuberculosis of spine (Thoracic region)
0.017 0.982 0.000
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.017 0.982 0.000
M49.02 Tuberculosis of spine (Cervical region)
0.017 0.982 0.000
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)
0.017 0.982 0.000
M49.00 Tuberculosis of spine (Multiple sites in spine)
0.017 0.982 0.000
M49.19 Brucella spondylitis (Site unspecified)
0.017 0.982 0.000
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)
0.017 0.982 0.000
M49.17 Brucella spondylitis (Lumbosacral region)
0.017 0.982 0.000
M49.16 Brucella spondylitis (Lumbar region)
0.017 0.982 0.000
M49.15 Brucella spondylitis (Thoracolumbar region)
0.017 0.982 0.000
M49.14 Brucella spondylitis (Thoracic region)
0.017 0.982 0.000
M49.13 Brucella spondylitis (Cervicothoracic region)
0.017 0.982 0.000
M49.12 Brucella spondylitis (Cervical region)
0.017 0.982 0.000
M49.11 Brucella spondylitis (Occipito-atlanto-axial region)
0.017 0.982 0.000
M49.10 Brucella spondylitis (Multiple sites in spine)
0.017 0.982 0.000
M49.29 Enterobacterial spondylitis (Site unspecified)
0.017 0.982 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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