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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844509
log Bayes Factor = 45.9217
Chromosome 6   position 31,510,924  (GRCh37) Explore rs2844509 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E10.9 Without complications
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
E10-E14 Diabetes mellitus
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.002 0.998
J47 Bronchiectasis
0.000 0.005 0.995
J40-J47 Chronic lower respiratory diseases
0.000 0.012 0.988
J44 Other chronic obstructive pulmonary disease
0.000 0.014 0.986
J33 Nasal polyp
0.000 0.018 0.982
J33.9 Nasal polyp, unspecified
0.000 0.021 0.979
J33.0 Polyp of nasal cavity
0.000 0.021 0.979
E06 Thyroiditis
0.000 0.023 0.977
L40.0 Psoriasis vulgaris
0.977 0.023 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.030 0.970
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.034 0.966
Chapter X Diseases of the respiratory system
0.000 0.036 0.964
J30-J39 Other diseases of upper respiratory tract
0.000 0.040 0.960
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.047 0.953
E06.3 Autoimmune thyroiditis
0.000 0.055 0.945
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.056 0.944
E10.1 With ketoacidosis
0.000 0.057 0.943
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.061 0.939
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.067 0.933
M06 Other rheumatoid arthritis
0.000 0.080 0.920
E70-E90 Metabolic disorders
0.000 0.089 0.911
J80 Adult respiratory distress syndrome
0.000 0.100 0.900
E10.3 With ophthalmic complications
0.000 0.105 0.895
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.111 0.889
L40.1 Generalised pustular psoriasis
0.885 0.115 0.000
E10.2 With renal complications
0.000 0.115 0.885
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.116 0.884
J32 Chronic sinusitis
0.000 0.116 0.884
E89.0 Postprocedural hypothyroidism
0.000 0.117 0.883
J81 Pulmonary oedema
0.000 0.120 0.880
M06.0 Seronegative rheumatoid arthritis
0.000 0.155 0.845
E06.9 Thyroiditis, unspecified
0.000 0.166 0.834
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.175 0.825
J35 Chronic diseases of tonsils and adenoids
0.000 0.182 0.818
J00-J06 Acute upper respiratory infections
0.000 0.197 0.803
E73 Lactose intolerance
0.000 0.199 0.801
E10.8 With unspecified complications
0.000 0.202 0.798
L40.8 Other psoriasis
0.795 0.205 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.207 0.793
E27.1 Primary adrenocortical insufficiency
0.000 0.210 0.790
E27 Other disorders of adrenal gland
0.000 0.211 0.789
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.213 0.786
E40-E46 Malnutrition
0.000 0.215 0.785
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.217 0.783
E10.0 With coma
0.000 0.217 0.783
J00 Acute nasopharyngitis [common cold]
0.000 0.219 0.781
L40.4 Guttate psoriasis
0.776 0.224 0.000
J32.8 Other chronic sinusitis
0.000 0.224 0.776
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.225 0.775
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.233 0.767
J32.0 Chronic maxillary sinusitis
0.000 0.234 0.766
E10.4 With neurological complications
0.000 0.235 0.765
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.247 0.753
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.000 0.250 0.750
M06.3 Rheumatoid nodule
0.000 0.253 0.747
E50-E64 Other nutritional deficiencies
0.000 0.254 0.746
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.254 0.745
E03.8 Other specified hypothyroidism
0.000 0.258 0.742
E04 Other non-toxic goitre
0.000 0.259 0.741
J33.8 Other polyp of sinus
0.000 0.260 0.740
J32.1 Chronic frontal sinusitis
0.000 0.261 0.738
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.266 0.734
E05.8 Other thyrotoxicosis
0.000 0.269 0.731
E73.9 Lactose intolerance, unspecified
0.000 0.277 0.723
E86 Volume depletion
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
J33.1 Polypoid sinus degeneration
0.000 0.296 0.704
E06.5 Other chronic thyroiditis
0.000 0.300 0.700
E06.4 Drug-induced thyroiditis
0.000 0.300 0.700
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.300 0.700
E06.1 Subacute thyroiditis
0.000 0.300 0.700
E06.0 Acute thyroiditis
0.000 0.300 0.700
J35.0 Chronic tonsillitis
0.000 0.303 0.697
E79 Disorders of purine and pyrimidine metabolism
0.000 0.305 0.695
J32.2 Chronic ethmoidal sinusitis
0.000 0.306 0.694
E10.6 With other specified complications
0.000 0.308 0.692
M06.4 Inflammatory polyarthropathy
0.000 0.312 0.688
E04.0 Non-toxic diffuse goitre
0.000 0.316 0.684
J41 Simple and mucopurulent chronic bronchitis
0.000 0.317 0.683
E89.3 Postprocedural hypopituitarism
0.000 0.330 0.670
J01 Acute sinusitis
0.000 0.331 0.669
E53 Deficiency of other B group vitamins
0.000 0.331 0.669
J42 Unspecified chronic bronchitis
0.000 0.339 0.660
E80.4 Gilbert's syndrome
0.000 0.340 0.660
M06.8 Other specified rheumatoid arthritis
0.000 0.340 0.660
M06.2 Rheumatoid bursitis
0.000 0.340 0.660
M06.1 Adult-onset Still's disease
0.000 0.340 0.660
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.343 0.657
M06.34 Rheumatoid nodule (Hand)
0.000 0.346 0.654
E84 Cystic fibrosis
0.000 0.347 0.653
E77 Disorders of glycoprotein metabolism
0.000 0.347 0.653
E76 Disorders of glycosaminoglycan metabolism
0.000 0.347 0.653
E72 Other disorders of amino-acid metabolism
0.000 0.347 0.653
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.347 0.653
E70 Disorders of aromatic amino-acid metabolism
0.000 0.347 0.653
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.347 0.653
E10.5 With peripheral circulatory complications
0.000 0.348 0.652
E27.2 Addisonian crisis
0.000 0.355 0.645
E65-E68 Obesity and other hyperalimentation
0.000 0.361 0.639
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.363 0.637
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.363 0.637
E89.5 Postprocedural testicular hypofunction
0.000 0.363 0.637
E89.4 Postprocedural ovarian failure
0.000 0.363 0.637
E89.1 Postprocedural hypoinsulinaemia
0.000 0.363 0.637
J32.3 Chronic sphenoidal sinusitis
0.000 0.366 0.634
E46 Unspecified protein-energy malnutrition
0.000 0.369 0.631
E16 Other disorders of pancreatic internal secretion
0.000 0.371 0.629
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.383 0.616
E03.1 Congenital hypothyroidism without goitre
0.000 0.385 0.614
J20-J22 Other acute lower respiratory infections
0.000 0.387 0.613
E80.6 Other disorders of bilirubin metabolism
0.000 0.388 0.612
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.389 0.610
E20 Hypoparathyroidism
0.000 0.391 0.609
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.392 0.608
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.394 0.606
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.394 0.606
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.394 0.606
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.394 0.606
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.394 0.606
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.394 0.606
E53.8 Deficiency of other specified B group vitamins
0.000 0.399 0.601
E27.9 Disorder of adrenal gland, unspecified
0.000 0.404 0.596
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.407 0.593
J32.4 Chronic pansinusitis
0.000 0.412 0.588
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids
0.000 0.413 0.587
M05-M14 Inflammatory polyarthropathies
0.001 0.416 0.583
E04.1 Non-toxic single thyroid nodule
0.000 0.418 0.582
E85 Amyloidosis
0.000 0.421 0.579
E88 Other metabolic disorders
0.000 0.425 0.575
E73.8 Other lactose intolerance
0.000 0.425 0.574
E73.1 Secondary lactase deficiency
0.000 0.425 0.574
E73.0 Congenital lactase deficiency
0.000 0.425 0.574
J04 Acute laryngitis and tracheitis
0.000 0.426 0.573
J35.1 Hypertrophy of tonsils
0.000 0.430 0.569
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.432 0.568
E32 Diseases of thymus
0.000 0.432 0.568
E31 Polyglandular dysfunction
0.000 0.432 0.568
E30 Disorders of puberty, not elsewhere classified
0.000 0.432 0.568
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.432 0.568
E27.5 Adrenomedullary hyperfunction
0.000 0.434 0.566
E27.0 Other adrenocortical overactivity
0.000 0.434 0.566
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.437 0.562
E45 Retarded development following protein-energy malnutrition
0.000 0.437 0.562
E43 Unspecified severe protein-energy malnutrition
0.000 0.437 0.562
E42 Marasmic kwashiorkor
0.000 0.437 0.562
E41 Nutritional marasmus
0.000 0.437 0.562
E40 Kwashiorkor
0.000 0.437 0.562
E15 Nondiabetic hypoglycaemic coma
0.000 0.438 0.562
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.440 0.560
M05 Seropositive rheumatoid arthritis
0.000 0.442 0.557
E65 Localised adiposity
0.000 0.445 0.555
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.450 0.550
E80.5 Crigler-Najjar syndrome
0.000 0.450 0.550
E80.3 Defects of catalase and peroxydase
0.000 0.450 0.550
E80.1 Porphyria cutanea tarda
0.000 0.450 0.550
E80.0 Hereditary erythropoietic porphyria
0.000 0.450 0.550
J01.0 Acute maxillary sinusitis
0.000 0.452 0.548
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.458 0.542
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.460 0.540
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.460 0.540
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.461 0.539
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.462 0.537
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.464 0.536
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.465 0.535
M06.38 Rheumatoid nodule (Other)
0.000 0.465 0.535
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.465 0.535
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.465 0.535
M06.33 Rheumatoid nodule (Forearm)
0.000 0.465 0.535
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.465 0.535
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.465 0.535
E63 Other nutritional deficiencies
0.000 0.465 0.535
E56 Other vitamin deficiencies
0.000 0.465 0.535
E51 Thiamine deficiency
0.000 0.465 0.535
E50 Vitamin A deficiency
0.000 0.465 0.535
E60 Dietary zinc deficiency
0.000 0.465 0.535
E59 Dietary selenium deficiency
0.000 0.465 0.535
E54 Ascorbic acid deficiency
0.000 0.465 0.535
E52 Niacin deficiency [pellagra]
0.000 0.465 0.535
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.466 0.534
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.468 0.532
E04.8 Other specified non-toxic goitre
0.000 0.468 0.532
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.470 0.530
E22 Hyperfunction of pituitary gland
0.000 0.471 0.529
E74 Other disorders of carbohydrate metabolism
0.000 0.471 0.528
E07 Other disorders of thyroid
0.000 0.472 0.528
J35.2 Hypertrophy of adenoids
0.000 0.473 0.527
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.474 0.526
E34 Other endocrine disorders
0.000 0.480 0.520
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.480 0.520
J01.9 Acute sinusitis, unspecified
0.000 0.481 0.519
M10 Gout
0.000 0.485 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E53.9 Vitamin B deficiency, unspecified
0.000 0.486 0.514
E25 Adrenogenital disorders
0.000 0.487 0.513
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E26 Hyperaldosteronism
0.000 0.488 0.511
J37 Chronic laryngitis and laryngotracheitis
0.001 0.490 0.510
E13 Other specified diabetes mellitus
0.001 0.497 0.503
E58 Dietary calcium deficiency
0.000 0.499 0.501
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.501 0.498
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.501 0.498
E79.1 Lesch-Nyhan syndrome
0.000 0.501 0.498
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.506 0.493
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.506 0.493
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.506 0.493
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.506 0.493
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.506 0.493
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.506 0.493
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.506 0.493
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.506 0.493
E27.8 Other specified disorders of adrenal gland
0.000 0.507 0.493
E16.2 Hypoglycaemia, unspecified
0.000 0.508 0.492
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.510 0.490
J41.1 Mucopurulent chronic bronchitis
0.000 0.510 0.490
J04.0 Acute laryngitis
0.000 0.513 0.487
J86 Pyothorax
0.000 0.515 0.485
E28 Ovarian dysfunction
0.000 0.515 0.485
J84 Other interstitial pulmonary diseases
0.000 0.516 0.484
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.516 0.484
E29 Testicular dysfunction
0.000 0.518 0.482
J01.8 Other acute sinusitis
0.000 0.520 0.480
J01.4 Acute pansinusitis
0.000 0.520 0.480
J01.3 Acute sphenoidal sinusitis
0.000 0.520 0.480
J01.2 Acute ethmoidal sinusitis
0.000 0.520 0.480
J01.1 Acute frontal sinusitis
0.000 0.520 0.480
E53.1 Pyridoxine deficiency
0.000 0.520 0.480
E53.0 Riboflavin deficiency
0.000 0.520 0.480
E20.9 Hypoparathyroidism, unspecified
0.000 0.522 0.478
J40 Bronchitis, not specified as acute or chronic
0.000 0.523 0.477
E80.2 Other porphyria
0.000 0.526 0.474
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.526 0.474
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.527 0.473
M06.18 Adult-onset Still's disease (Other)
0.000 0.527 0.473
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.527 0.473
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.527 0.473
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.527 0.473
M06.14 Adult-onset Still's disease (Hand)
0.000 0.527 0.473
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.527 0.473
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.527 0.473
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.527 0.473
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.527 0.473
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.527 0.473
M06.28 Rheumatoid bursitis (Other)
0.000 0.527 0.473
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.527 0.473
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.527 0.473
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.527 0.473
M06.24 Rheumatoid bursitis (Hand)
0.000 0.527 0.473
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.527 0.473
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.527 0.473
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.527 0.473
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.527 0.473
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.527 0.473
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.527 0.473
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.527 0.473
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.527 0.473
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.527 0.473
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.527 0.473
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.527 0.473
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.527 0.473
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.527 0.473
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.527 0.473
E61 Deficiency of other nutrient elements
0.000 0.530 0.470
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.532 0.468
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.532 0.468
E70.3 Albinism
0.000 0.532 0.468
E70.2 Disorders of tyrosine metabolism
0.000 0.532 0.468
E70.1 Other hyperphenylalaninaemias
0.000 0.532 0.468
E70.0 Classical phenylketonuria
0.000 0.532 0.468
E71.3 Disorders of fatty-acid metabolism
0.000 0.532 0.468
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.532 0.468
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.532 0.468
E71.0 Maple-syrup-urine disease
0.000 0.532 0.468
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.532 0.468
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.532 0.468
E72.5 Disorders of glycine metabolism
0.000 0.532 0.468
E72.4 Disorders of ornithine metabolism
0.000 0.532 0.468
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.532 0.468
E72.2 Disorders of urea cycle metabolism
0.000 0.532 0.468
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.532 0.468
E72.0 Disorders of amino-acid transport
0.000 0.532 0.468
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.532 0.468
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.532 0.468
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.532 0.468
E76.2 Other mucopolysaccharidoses
0.000 0.532 0.468
E76.1 Mucopolysaccharidosis, type II
0.000 0.532 0.468
E76.0 Mucopolysaccharidosis, type I
0.000 0.532 0.468
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.532 0.468
E77.8 Other disorders of glycoprotein metabolism
0.000 0.532 0.468
E77.1 Defects in glycoprotein degradation
0.000 0.532 0.468
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.532 0.468
E84.9 Cystic fibrosis, unspecified
0.000 0.532 0.468
E84.8 Cystic fibrosis with other manifestations
0.000 0.532 0.468
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.532 0.468
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.532 0.468
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.532 0.467
J41.0 Simple chronic bronchitis
0.000 0.535 0.464
J21 Acute bronchiolitis
0.000 0.536 0.464
J60-J70 Lung diseases due to external agents
0.000 0.536 0.464
J31.1 Chronic nasopharyngitis
0.000 0.539 0.461
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.540 0.460
E67 Other hyperalimentation
0.000 0.542 0.458
E68 Sequelae of hyperalimentation
0.000 0.542 0.458
E23 Hypofunction and other disorders of pituitary gland
0.000 0.544 0.456
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.545 0.455
E85.4 Organ-limited amyloidosis
0.000 0.547 0.453
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.549 0.451
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.549 0.451
E16.4 Abnormal secretion of gastrin
0.000 0.549 0.451
E16.3 Increased secretion of glucagon
0.000 0.549 0.451
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.550 0.449
E75.6 Lipid storage disorder, unspecified
0.000 0.558 0.442
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.558 0.442
E75.3 Sphingolipidosis, unspecified
0.000 0.558 0.442
E75.2 Other sphingolipidosis
0.000 0.558 0.442
E75.1 Other gangliosidosis
0.000 0.558 0.442
E75.0 GM2 gangliosidosis
0.000 0.558 0.442
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.559 0.441
M12 Other specific arthropathies
0.001 0.560 0.440
E87.0 Hyperosmolality and hypernatraemia
0.000 0.560 0.440
J03 Acute tonsillitis
0.000 0.562 0.437
E20.8 Other hypoparathyroidism
0.000 0.563 0.437
E20.1 Pseudohypoparathyroidism
0.000 0.563 0.437
E20.0 Idiopathic hypoparathyroidism
0.000 0.563 0.437
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.563 0.436
J43 Emphysema
0.000 0.565 0.435
J95-J99 Other diseases of the respiratory system
0.000 0.566 0.434
E78.1 Pure hyperglyceridaemia
0.000 0.568 0.432
J30 Vasomotor and allergic rhinitis
0.000 0.568 0.432
M10.9 Gout, unspecified
0.000 0.569 0.431
E78.2 Mixed hyperlipidaemia
0.000 0.569 0.431
E22.0 Acromegaly and pituitary gigantism
0.000 0.571 0.429
M10.0 Idiopathic gout
0.000 0.571 0.428
J31.2 Chronic pharyngitis
0.000 0.573 0.427
E55 Vitamin D deficiency
0.000 0.578 0.421
E87.7 Fluid overload
0.000 0.579 0.421
J85 Abscess of lung and mediastinum
0.000 0.580 0.420
M09 Juvenile arthritis in diseases classified elsewhere
0.001 0.581 0.418
M08 Juvenile arthritis
0.001 0.581 0.418
J20 Acute bronchitis
0.000 0.583 0.417
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.584 0.415
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.584 0.415
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.584 0.415
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.585 0.415
E88.9 Metabolic disorder, unspecified
0.000 0.588 0.412
E88.3 Tumour lysis syndrome
0.000 0.588 0.412
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.588 0.412
J04.2 Acute laryngotracheitis
0.000 0.589 0.411
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.591 0.408
J46 Status asthmaticus
0.000 0.592 0.408
E89.2 Postprocedural hypoparathyroidism
0.000 0.592 0.407
E30.9 Disorder of puberty, unspecified
0.000 0.592 0.407
E30.8 Other disorders of puberty
0.000 0.592 0.407
E30.1 Precocious puberty
0.000 0.592 0.407
E30.0 Delayed puberty
0.000 0.592 0.407
E31.9 Polyglandular dysfunction, unspecified
0.000 0.592 0.407
E31.8 Other polyglandular dysfunction
0.000 0.592 0.407
E31.1 Polyglandular hyperfunction
0.000 0.592 0.407
E31.0 Autoimmune polyglandular failure
0.000 0.592 0.407
E32.9 Disease of thymus, unspecified
0.000 0.592 0.407
E32.8 Other diseases of thymus
0.000 0.592 0.407
E32.1 Abscess of thymus
0.000 0.592 0.407
E32.0 Persistent hyperplasia of thymus
0.000 0.592 0.407
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.592 0.407
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.592 0.407
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.592 0.407
M10.94 Gout, unspecified (Hand)
0.000 0.593 0.407
E75.5 Other lipid storage disorders
0.000 0.594 0.405
E44.1 Mild protein-energy malnutrition
0.000 0.596 0.403
E44.0 Moderate protein-energy malnutrition
0.000 0.596 0.403
E78.4 Other hyperlipidaemia
0.000 0.600 0.400
M05.8 Other seropositive rheumatoid arthritis
0.000 0.600 0.400
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.600 0.400
M05.2 Rheumatoid vasculitis
0.000 0.600 0.400
M05.1 Rheumatoid lung disease
0.000 0.600 0.400
M05.0 Felty's syndrome
0.000 0.600 0.400
E85.3 Secondary systemic amyloidosis
0.000 0.602 0.397
E22.1 Hyperprolactinaemia
0.000 0.607 0.393
E34.8 Other specified endocrine disorders
0.000 0.610 0.390
E78.3 Hyperchylomicronaemia
0.000 0.611 0.388
E78.6 Lipoprotein deficiency
0.000 0.613 0.387
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.613 0.386
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.613 0.386
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.613 0.386
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.613 0.386
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.613 0.386
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.613 0.386
E85.8 Other amyloidosis
0.000 0.614 0.386
E50.9 Vitamin A deficiency, unspecified
0.000 0.616 0.384
E50.8 Other manifestations of vitamin A deficiency
0.000 0.616 0.384
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.616 0.384
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.616 0.384
E50.5 Vitamin A deficiency with night blindness
0.000 0.616 0.384
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.616 0.384
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.616 0.384
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.616 0.384
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.616 0.384
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.616 0.384
E51.9 Thiamine deficiency, unspecified
0.000 0.616 0.384
E51.8 Other manifestations of thiamine deficiency
0.000 0.616 0.384
E51.2 Wernicke's encephalopathy
0.000 0.616 0.384
E51.1 Beriberi
0.000 0.616 0.384
E56.9 Vitamin deficiency, unspecified
0.000 0.616 0.384
E56.8 Deficiency of other vitamins
0.000 0.616 0.384
E56.1 Deficiency of vitamin K
0.000 0.616 0.384
E56.0 Deficiency of vitamin E
0.000 0.616 0.384
E63.9 Nutritional deficiency, unspecified
0.000 0.616 0.384
E63.8 Other specified nutritional deficiencies
0.000 0.616 0.384
E63.1 Imbalance of constituents of food intake
0.000 0.616 0.384
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.616 0.384
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.616 0.384
E64.8 Sequelae of other nutritional deficiencies
0.000 0.616 0.384
E64.3 Sequelae of rickets
0.000 0.616 0.384
E64.2 Sequelae of vitamin C deficiency
0.000 0.616 0.384
E64.1 Sequelae of vitamin A deficiency
0.000 0.616 0.384
E64.0 Sequelae of protein-energy malnutrition
0.000 0.616 0.384
J32.9 Chronic sinusitis, unspecified
0.000 0.618 0.382
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.621 0.379
E22.8 Other hyperfunction of pituitary gland
0.000 0.621 0.379
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.621 0.379
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.621 0.379
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.621 0.379
E74.2 Disorders of galactose metabolism
0.000 0.621 0.379
E74.1 Disorders of fructose metabolism
0.000 0.621 0.379
E07.1 Dyshormogenetic goitre
0.000 0.621 0.378
E07.0 Hypersecretion of calcitonin
0.000 0.621 0.378
J36 Peritonsillar abscess
0.000 0.625 0.375
E04.9 Non-toxic goitre, unspecified
0.000 0.626 0.374
E88.8 Other specified metabolic disorders
0.000 0.626 0.373
E34.5 Androgen resistance syndrome
0.000 0.627 0.373
E34.4 Constitutional tall stature
0.000 0.627 0.373
E34.3 Short stature, not elsewhere classified
0.000 0.627 0.373
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.627 0.373
E34.1 Other hypersecretion of intestinal hormones
0.000 0.627 0.373
M10.4 Other secondary gout
0.000 0.631 0.369
M10.3 Gout due to impairment of renal function
0.000 0.631 0.369
M10.2 Drug-induced gout
0.000 0.631 0.369
M10.1 Lead-induced gout
0.000 0.631 0.369
E25.9 Adrenogenital disorder, unspecified
0.000 0.632 0.368
E25.8 Other adrenogenital disorders
0.000 0.632 0.368
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.632 0.368
E14 Unspecified diabetes mellitus
0.000 0.632 0.368
E26.9 Hyperaldosteronism, unspecified
0.000 0.633 0.367
E26.8 Other hyperaldosteronism
0.000 0.633 0.367
E26.1 Secondary hyperaldosteronism
0.000 0.633 0.367
J37.1 Chronic laryngotracheitis
0.001 0.634 0.366
L40-L45 Papulosquamous disorders
0.274 0.635 0.091
E34.9 Endocrine disorder, unspecified
0.000 0.637 0.363
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.638 0.361
E13.8 With unspecified complications
0.001 0.639 0.360
E13.7 With multiple complications
0.001 0.639 0.360
E13.6 With other specified complications
0.001 0.639 0.360
E13.5 With peripheral circulatory complications
0.001 0.639 0.360
E13.4 With neurological complications
0.001 0.639 0.360
E13.3 With ophthalmic complications
0.001 0.639 0.360

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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