TreeWAS – Variant ID: rs2844569

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
L40 Psoriasis	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	0.000	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.000	1.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
E20-E35 Disorders of other endocrine glands	1.000	0.000	0.000
E27 Other disorders of adrenal gland	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.999	0.001	0.000
E27.1 Primary adrenocortical insufficiency	0.999	0.001	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.999	0.001	0.000
M35 Other systemic involvement of connective tissue	0.999	0.001	0.000
M35.0 Sicca syndrome [Sjogren]	0.999	0.001	0.000
K50.9 Crohn's disease, unspecified	0.000	0.002	0.998
E10.1 With ketoacidosis	0.998	0.002	0.000
I73 Other peripheral vascular diseases	0.998	0.002	0.000
M35.3 Polymyalgia rheumatica	0.997	0.003	0.000
K50-K52 Noninfective enteritis and colitis	0.001	0.003	0.996
E14.9 Without complications	0.995	0.005	0.000
I74 Arterial embolism and thrombosis	0.995	0.005	0.000
K51 Ulcerative colitis	0.000	0.006	0.994
J33.0 Polyp of nasal cavity	0.994	0.006	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.992	0.008	0.000
I77 Other disorders of arteries and arterioles	0.990	0.010	0.000
L40.0 Psoriasis vulgaris	0.000	0.011	0.989
K50.0 Crohn's disease of small intestine	0.000	0.011	0.989
I73.9 Peripheral vascular disease, unspecified	0.988	0.012	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.987	0.013	0.000
J33 Nasal polyp	0.987	0.013	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.014	0.986
K50.1 Crohn's disease of large intestine	0.000	0.017	0.983
I73.0 Raynaud's syndrome	0.982	0.018	0.000
K90 Intestinal malabsorption	0.980	0.020	0.000
I77.1 Stricture of artery	0.978	0.022	0.000
J33.9 Nasal polyp, unspecified	0.977	0.023	0.000
E14.3 With ophthalmic complications	0.963	0.037	0.000
M06 Other rheumatoid arthritis	0.955	0.045	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.953	0.047	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.951	0.049	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.948	0.052	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.948	0.052	0.000
I77.6 Arteritis, unspecified	0.937	0.063	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.934	0.066	0.000
M05-M14 Inflammatory polyarthropathies	0.928	0.072	0.000
K90.9 Intestinal malabsorption, unspecified	0.920	0.080	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.919	0.081	0.000
I74.8 Embolism and thrombosis of other arteries	0.917	0.083	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.916	0.084	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.084	0.916
E16 Other disorders of pancreatic internal secretion	0.911	0.089	0.000
M20-M25 Other joint disorders	0.911	0.089	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.907	0.093	0.000
K75.4 Autoimmune hepatitis	0.898	0.102	0.000
K75 Other inflammatory liver diseases	0.895	0.105	0.000
E07 Other disorders of thyroid	0.895	0.105	0.000
K70-K77 Diseases of liver	0.891	0.109	0.000
M34 Systemic sclerosis	0.888	0.112	0.000
M06.3 Rheumatoid nodule	0.883	0.117	0.000
K90-K93 Other diseases of the digestive system	0.882	0.118	0.000
Chapter XI Diseases of the digestive system	0.877	0.123	0.000
J33.8 Other polyp of sinus	0.877	0.123	0.000
# Top node	0.875	0.125	0.000
M32 Systemic lupus erythematosus	0.875	0.125	0.000
M35.1 Other overlap syndromes	0.874	0.126	0.000
K73 Chronic hepatitis, not elsewhere classified	0.874	0.126	0.000
E10.2 With renal complications	0.871	0.129	0.000
E16.2 Hypoglycaemia, unspecified	0.868	0.132	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.135	0.865
M80-M85 Disorders of bone density and structure	0.856	0.144	0.000
M05 Seropositive rheumatoid arthritis	0.851	0.149	0.000
E23 Hypofunction and other disorders of pituitary gland	0.851	0.149	0.000
Chapter VIII Diseases of the ear and mastoid process	0.848	0.152	0.000
E28 Ovarian dysfunction	0.841	0.159	0.000
E10.0 With coma	0.839	0.161	0.000
E07.8 Other specified disorders of thyroid	0.835	0.165	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.834	0.166	0.000
K51.4 Pseudopolyposis of colon	0.000	0.166	0.834
E06 Thyroiditis	0.832	0.168	0.000
M34.9 Systemic sclerosis, unspecified	0.830	0.170	0.000
K73.9 Chronic hepatitis, unspecified	0.829	0.171	0.000
H60-H62 Diseases of external ear	0.829	0.171	0.000
K75.8 Other specified inflammatory liver diseases	0.825	0.175	0.000
M81 Osteoporosis without pathological fracture	0.825	0.175	0.000
K74 Fibrosis and cirrhosis of liver	0.824	0.176	0.000
E22 Hyperfunction of pituitary gland	0.815	0.185	0.000
E10.8 With unspecified complications	0.814	0.186	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.810	0.190	0.000
H61 Other disorders of external ear	0.808	0.192	0.000
K74.3 Primary biliary cirrhosis	0.805	0.195	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.803	0.197	0.000
E23.2 Diabetes insipidus	0.803	0.197	0.000
I71 Aortic aneurysm and dissection	0.803	0.197	0.000
E10.6 With other specified complications	0.802	0.198	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.800	0.200	0.000
E14.6 With other specified complications	0.799	0.201	0.000
E14.5 With peripheral circulatory complications	0.796	0.204	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.791	0.209	0.000
E14.1 With ketoacidosis	0.789	0.211	0.000
I70 Atherosclerosis	0.785	0.215	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.784	0.216	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.784	0.216	0.000
M06.34 Rheumatoid nodule (Hand)	0.784	0.216	0.000
K51.8 Other ulcerative colitis	0.000	0.216	0.784
J33.1 Polypoid sinus degeneration	0.780	0.220	0.000
M12 Other specific arthropathies	0.780	0.220	0.000
E14.2 Withrenal complications	0.778	0.222	0.000
I74.5 Embolism and thrombosis of iliac artery	0.775	0.225	0.000
E10.4 With neurological complications	0.774	0.226	0.000
E31 Polyglandular dysfunction	0.773	0.227	0.000
M10 Gout	0.772	0.228	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.771	0.229	0.000
E06.3 Autoimmune thyroiditis	0.770	0.230	0.000
M34.8 Other forms of systemic sclerosis	0.763	0.237	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.758	0.242	0.000
M35.8 Other specified systemic involvement of connective tissue	0.758	0.242	0.000
H80-H83 Diseases of inner ear	0.754	0.246	0.000
M80 Osteoporosis with pathological fracture	0.754	0.246	0.000
E16.1 Other hypoglycaemia	0.752	0.248	0.000
M81.9 Osteoporosis, unspecified	0.752	0.248	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.751	0.249	0.000
K50.8 Other Crohn's disease	0.000	0.250	0.750
E03.0 Congenital hypothyroidism with diffuse goitre	0.745	0.255	0.000
J45 Asthma	0.745	0.255	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.744	0.256	0.000
E10.7 With multiple complications	0.742	0.258	0.000
E25 Adrenogenital disorders	0.740	0.259	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.739	0.261	0.000
Chapter IX Diseases of the circulatory system	0.739	0.261	0.000
H80 Otosclerosis	0.736	0.264	0.000
E03.8 Other specified hypothyroidism	0.734	0.266	0.000
M34.1 CR(E)ST syndrome	0.733	0.267	0.000
Chapter I Certain infectious and parasitic diseases	0.732	0.268	0.000
H61.3 Acquired stenosis of external ear canal	0.730	0.270	0.000
E28.3 Primary ovarian failure	0.729	0.271	0.000
E10.5 With peripheral circulatory complications	0.726	0.274	0.000
M35.7 Hypermobility syndrome	0.725	0.275	0.000
L40.8 Other psoriasis	0.000	0.275	0.725
H80.9 Otosclerosis, unspecified	0.724	0.276	0.000
L40.3 Pustulosis palmaris et plantaris	0.000	0.277	0.723
K52 Other non-infective gastro-enteritis and colitis	0.000	0.277	0.723
H61.8 Other specified disorders of external ear	0.722	0.278	0.000
E24 Cushing's syndrome	0.721	0.279	0.000
M32.8 Other forms of systemic lupus erythematosus	0.720	0.280	0.000
I77.2 Rupture of artery	0.719	0.281	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.719	0.281	0.000
K51.5 Mucosal proctocolitis	0.000	0.282	0.718
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
L40.4 Guttate psoriasis	0.000	0.283	0.717
L40.2 Acrodermatitis continua	0.000	0.283	0.717
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.717	0.283	0.000
E32 Diseases of thymus	0.717	0.283	0.000
E30 Disorders of puberty, not elsewhere classified	0.717	0.283	0.000
E27.5 Adrenomedullary hyperfunction	0.717	0.283	0.000
E27.0 Other adrenocortical overactivity	0.717	0.283	0.000
H61.1 Non-infective disorders of pinna	0.716	0.284	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.716	0.284	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.716	0.284	0.000
M35.5 Multifocal fibrosclerosis	0.716	0.284	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.716	0.284	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.712	0.288	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.711	0.289	0.000
L40.1 Generalised pustular psoriasis	0.000	0.289	0.710
K75.3 Granulomatous hepatitis, not elsewhere classified	0.710	0.290	0.000
I77.5 Necrosis of artery	0.710	0.290	0.000
I77.4 Coeliac artery compression syndrome	0.710	0.290	0.000
I77.3 Arterial fibromuscular dysplasia	0.710	0.290	0.000
M35.2 Behcet's disease	0.709	0.291	0.000
K77 Liver disorders in diseases classified elsewhere	0.707	0.293	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.707	0.293	0.000
D69 Purpura and other haemorrhagic conditions	0.705	0.295	0.000
K60.2 Anal fissure, unspecified	0.705	0.295	0.000
M81.98 Osteoporosis, unspecified (Other)	0.704	0.296	0.000
K90.3 Pancreatic steatorrhoea	0.702	0.297	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.702	0.297	0.000
K90.1 Tropical sprue	0.702	0.297	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.702	0.298	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.700	0.299	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.700	0.300	0.000
E20 Hypoparathyroidism	0.694	0.305	0.000
M10.0 Idiopathic gout	0.691	0.309	0.000
E14.8 With unspecified complications	0.689	0.310	0.000
E27.9 Disorder of adrenal gland, unspecified	0.687	0.313	0.000
K90.8 Other intestinal malabsorption	0.685	0.315	0.000
M06.2 Rheumatoid bursitis	0.684	0.315	0.000
M06.1 Adult-onset Still's disease	0.684	0.315	0.000
I79.1 Aortitis in diseases classified elsewhere	0.683	0.316	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.683	0.316	0.000
M81.0 Postmenopausal osteoporosis	0.683	0.317	0.000
M81.2 Osteoporosis of disuse	0.681	0.319	0.000
A30-A49 Other bacterial diseases	0.681	0.319	0.000
E15 Nondiabetic hypoglycaemic coma	0.680	0.320	0.000
A41 Other septicaemia	0.678	0.322	0.000
H60 Otitis externa	0.675	0.325	0.000
E13 Other specified diabetes mellitus	0.674	0.326	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.674	0.326	0.000
E27.2 Addisonian crisis	0.672	0.328	0.000
K60 Fissure and fistula of anal and rectal regions	0.666	0.334	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.665	0.334	0.000
M86-M90 Other osteopathies	0.665	0.335	0.000
A41.9 Septicaemia, unspecified	0.663	0.337	0.000
M31 Other necrotising vasculopathies	0.663	0.337	0.000
M06.8 Other specified rheumatoid arthritis	0.660	0.339	0.000
M82 Osteoporosis in diseases classified elsewhere	0.660	0.340	0.000
M81.1 Postoophorectomy osteoporosis	0.660	0.340	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.660	0.340	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.658	0.342	0.000
M34.0 Progressive systemic sclerosis	0.657	0.343	0.000
M83 Adult osteomalacia	0.655	0.345	0.000
M05.1 Rheumatoid lung disease	0.655	0.345	0.000
I73.8 Other specified peripheral vascular diseases	0.654	0.346	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.654	0.346	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.654	0.346	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.653	0.347	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.653	0.347	0.000
E16.4 Abnormal secretion of gastrin	0.653	0.347	0.000
E16.3 Increased secretion of glucagon	0.653	0.347	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.652	0.348	0.000
A15-A19 Tuberculosis	0.651	0.349	0.000
M08 Juvenile arthritis	0.649	0.351	0.000
K52.3 Indeterminate colitis	0.000	0.353	0.647
H90-H95 Other disorders of ear	0.646	0.354	0.000
E03.1 Congenital hypothyroidism without goitre	0.645	0.355	0.000
D69.0 Allergic purpura	0.643	0.357	0.000
M05.8 Other seropositive rheumatoid arthritis	0.643	0.357	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.643	0.357	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.358	0.642
K75.2 Nonspecific reactive hepatitis	0.642	0.358	0.000
K75.1 Phlebitis of portal vein	0.642	0.358	0.000
E07.1 Dyshormogenetic goitre	0.642	0.358	0.000
E07.0 Hypersecretion of calcitonin	0.642	0.358	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.640	0.360	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.639	0.361	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.637	0.363	0.000
E14.4 With neurological complications	0.635	0.364	0.000
M14 Arthropathies in other diseases classified elsewhere	0.634	0.365	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.633	0.367	0.000
M06.38 Rheumatoid nodule (Other)	0.633	0.367	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.633	0.367	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.633	0.367	0.000
M06.33 Rheumatoid nodule (Forearm)	0.633	0.367	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.633	0.367	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.633	0.367	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.632	0.368	0.000
D69.4 Other primary thrombocytopenia	0.632	0.368	0.000
K74.5 Biliary cirrhosis, unspecified	0.631	0.369	0.000
E29 Testicular dysfunction	0.631	0.369	0.000
E23.6 Other disorders of pituitary gland	0.630	0.369	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.630	0.370	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.628	0.371	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.628	0.372	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.627	0.372	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.627	0.372	0.000
E40-E46 Malnutrition	0.627	0.373	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.626	0.374	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.626	0.374	0.000
H61.2 Impacted cerumen	0.625	0.375	0.000
M60-M63 Disorders of muscles	0.625	0.375	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.624	0.376	0.000
I71.0 Dissection of aorta [any part]	0.622	0.378	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.622	0.378	0.000
E23.7 Disorder of pituitary gland, unspecified	0.621	0.379	0.000
D69.6 Thrombocytopenia, unspecified	0.620	0.380	0.000
M30 Polyarteritis nodosa and related conditions	0.619	0.381	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.616	0.384	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.615	0.385	0.000
H61.0 Perichondritis of external ear	0.614	0.386	0.000
M12.5 Traumatic arthropathy	0.614	0.386	0.000
D55-D59 Haemolytic anaemias	0.614	0.386	0.000
E31.0 Autoimmune polyglandular failure	0.611	0.389	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.389	0.611
H60.9 Otitis externa, unspecified	0.611	0.389	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.610	0.389	0.000
K65-K67 Diseases of peritoneum	0.610	0.390	0.000
K60.0 Acute anal fissure	0.610	0.390	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.610	0.390	0.000
M05.2 Rheumatoid vasculitis	0.610	0.390	0.000
M05.0 Felty's syndrome	0.610	0.390	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.610	0.390	0.000
E23.1 Drug-induced hypopituitarism	0.610	0.390	0.000
B25-B34 Other viral diseases	0.609	0.391	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.608	0.392	0.000
I77.0 Arteriovenous fistula, acquired	0.606	0.394	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.605	0.395	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.604	0.396	0.000
B35-B49 Mycoses	0.604	0.396	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.603	0.397	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.603	0.397	0.000
E28.9 Ovarian dysfunction, unspecified	0.603	0.397	0.000
E28.8 Other ovarian dysfunction	0.603	0.397	0.000
E28.1 Androgen excess	0.603	0.397	0.000
E28.0 Oestrogen excess	0.603	0.397	0.000
H90 Conductive and sensorineural hearing loss	0.602	0.398	0.000
M86 Osteomyelitis	0.602	0.398	0.000
M65-M68 Disorders of synovium and tendon	0.601	0.399	0.000
K75.0 Abscess of liver	0.601	0.399	0.000
K60.1 Chronic anal fissure	0.601	0.399	0.000
E28.2 Polycystic ovarian syndrome	0.600	0.400	0.000
M12.2 Villonodular synovitis (pigmented)	0.599	0.401	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.598	0.402	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.598	0.402	0.000
E34 Other endocrine disorders	0.597	0.403	0.000
E06.4 Drug-induced thyroiditis	0.596	0.403	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.596	0.403	0.000
E06.1 Subacute thyroiditis	0.596	0.403	0.000
E06.0 Acute thyroiditis	0.596	0.403	0.000
E05.8 Other thyrotoxicosis	0.596	0.404	0.000
D80-D89 Certain disorders involving the immune mechanism	0.595	0.405	0.000
M31.3 Wegener's granulomatosis	0.595	0.405	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.594	0.406	0.000
E11 Non-insulin-dependent diabetes mellitus	0.594	0.406	0.000
M81.8 Other osteoporosis	0.591	0.408	0.000
M81.6 Localised osteoporosis [Lequesne]	0.591	0.408	0.000
M81.5 Idiopathic osteoporosis	0.591	0.408	0.000
K74.4 Secondary biliary cirrhosis	0.591	0.409	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.591	0.409	0.000
K74.1 Hepatic sclerosis	0.591	0.409	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.591	0.409	0.000
I77.8 Other specified disorders of arteries and arterioles	0.589	0.411	0.000
K71 Toxic liver disease	0.588	0.412	0.000
Chapter X Diseases of the respiratory system	0.588	0.412	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.587	0.413	0.000
E06.5 Other chronic thyroiditis	0.584	0.416	0.000
I70.9 Generalised and unspecified atherosclerosis	0.584	0.416	0.000
E22.8 Other hyperfunction of pituitary gland	0.584	0.416	0.000
J40-J47 Chronic lower respiratory diseases	0.582	0.418	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.581	0.418	0.000
M12.3 Palindromic rheumatism	0.580	0.419	0.000
E24.2 Drug-induced Cushing's syndrome	0.580	0.420	0.000
R31 Unspecified haematuria	0.000	0.420	0.580
E07.9 Disorder of thyroid, unspecified	0.580	0.420	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.578	0.422	0.000
M81.4 Drug-induced osteoporosis	0.576	0.424	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.576	0.424	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.576	0.424	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.576	0.424	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.576	0.424	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.575	0.425	0.000
K52.1 Toxic gastro-enteritis and colitis	0.000	0.427	0.573
E22.1 Hyperprolactinaemia	0.571	0.429	0.000
K60.5 Anorectal fistula	0.571	0.429	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.570	0.430	0.000
H92 Otalgia and effusion of ear	0.570	0.430	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.570	0.430	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.569	0.431	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.431	0.569
D69.9 Haemorrhagic condition, unspecified	0.566	0.434	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.560	0.440	0.000
I70.0 Atherosclerosis of aorta	0.559	0.440	0.000
M12.4 Intermittent hydrarthrosis	0.559	0.441	0.000
M12.1 Kaschin-Beck disease	0.559	0.441	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.559	0.441	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.558	0.442	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.557	0.443	0.000
B15-B19 Viral hepatitis	0.557	0.443	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.555	0.445	0.000
E31.9 Polyglandular dysfunction, unspecified	0.554	0.445	0.000
E31.8 Other polyglandular dysfunction	0.554	0.445	0.000
E31.1 Polyglandular hyperfunction	0.554	0.445	0.000
M10.06 Idiopathic gout (Lower leg)	0.554	0.446	0.000
M10.4 Other secondary gout	0.553	0.446	0.000
M10.3 Gout due to impairment of renal function	0.553	0.446	0.000
M10.2 Drug-induced gout	0.553	0.446	0.000
M10.1 Lead-induced gout	0.553	0.446	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.553	0.447	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.553	0.447	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.553	0.447	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.552	0.448	0.000
J45.0 Predominantly allergic asthma	0.552	0.448	0.000
E11.9 Without complications	0.551	0.449	0.000
E50-E64 Other nutritional deficiencies	0.550	0.450	0.000
H90.2 Conductive hearing loss, unspecified	0.550	0.450	0.000
I70.8 Atherosclerosis of other arteries	0.549	0.451	0.000
D69.8 Other specified haemorrhagic conditions	0.549	0.451	0.000
E26 Hyperaldosteronism	0.548	0.451	0.000
J84 Other interstitial pulmonary diseases	0.547	0.453	0.000
D60-D64 Aplastic and other anaemias	0.546	0.454	0.000
H90.3 Sensorineural hearing loss, bilateral	0.546	0.454	0.000
A20-A28 Certain zoonotic bacterial diseases	0.545	0.455	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.544	0.456	0.000
I70.1 Atherosclerosis of renal artery	0.544	0.456	0.000
B25 Cytomegaloviral disease	0.543	0.457	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.543	0.457	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.542	0.458	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.542	0.458	0.000
H60.5 Acute otitis externa, non-infective	0.541	0.459	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.540	0.459	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.540	0.459	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.540	0.459	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.540	0.459	0.000
M06.4 Inflammatory polyarthropathy	0.540	0.460	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.539	0.461	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.539	0.461	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.539	0.461	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.537	0.462	0.000
E22.0 Acromegaly and pituitary gigantism	0.536	0.464	0.000
M91-M94 Chondropathies	0.535	0.464	0.000
B35 Dermatophytosis	0.535	0.465	0.000
M11 Other crystal arthropathies	0.534	0.465	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.534	0.466	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.534	0.466	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.534	0.466	0.000
E24.0 Pituitary-dependent Cushing's disease	0.533	0.467	0.000
M66 Spontaneous rupture of synovium and tendon	0.532	0.468	0.000
K65 Peritonitis	0.532	0.468	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.531	0.469	0.000
D80 Immunodeficiency with predominantly antibody defects	0.531	0.469	0.000
J30-J39 Other diseases of upper respiratory tract	0.531	0.469	0.000
E25.9 Adrenogenital disorder, unspecified	0.531	0.469	0.000
E25.8 Other adrenogenital disorders	0.531	0.469	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.530	0.470	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.529	0.471	0.000
E24.8 Other Cushing's syndrome	0.529	0.471	0.000
J45.8 Mixed asthma	0.528	0.472	0.000
M86.9 Osteomyelitis, unspecified	0.528	0.472	0.000
H80.8 Other otosclerosis	0.528	0.472	0.000
H80.2 Cochlear otosclerosis	0.528	0.472	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.528	0.472	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.528	0.472	0.000
D69.5 Secondary thrombocytopenia	0.526	0.474	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.525	0.475	0.000
A75-A79 Rickettsioses	0.525	0.475	0.000
A70-A74 Other diseases caused by chlamydiae	0.525	0.475	0.000
M40-M43 Deforming dorsopathies	0.523	0.477	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.478	0.522
K74.6 Other and unspecified cirrhosis of liver	0.521	0.479	0.000
A18 Tuberculosis of other organs	0.520	0.480	0.000
E27.8 Other specified disorders of adrenal gland	0.520	0.480	0.000
M82.1 Osteoporosis in endocrine disorders	0.519	0.480	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.518	0.482	0.000
K65.8 Other peritonitis	0.518	0.482	0.000
M10.02 Idiopathic gout (Upper arm)	0.517	0.483	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.517	0.483	0.000
E24.3 Ectopic ACTH syndrome	0.517	0.483	0.000
E24.1 Nelson's syndrome	0.517	0.483	0.000
D69.2 Other nonthrombocytopenic purpura	0.517	0.483	0.000
A48 Other bacterial diseases, not elsewhere classified	0.516	0.484	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.515	0.485	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.514	0.485	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
E11.5 With peripheral circulatory complications	0.514	0.486	0.000
E30.9 Disorder of puberty, unspecified	0.514	0.486	0.000
E30.8 Other disorders of puberty	0.514	0.486	0.000
E30.1 Precocious puberty	0.514	0.486	0.000
E30.0 Delayed puberty	0.514	0.486	0.000
E32.9 Disease of thymus, unspecified	0.514	0.486	0.000
E32.8 Other diseases of thymus	0.514	0.486	0.000
E32.1 Abscess of thymus	0.514	0.486	0.000
E32.0 Persistent hyperplasia of thymus	0.514	0.486	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.514	0.486	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.514	0.486	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.514	0.486	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.513	0.486	0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.511	0.489	0.000
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed	0.510	0.490	0.000
A17 Tuberculosis of nervous system	0.510	0.490	0.000
B44 Aspergillosis	0.509	0.491	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.508	0.492	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations