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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844680
log Bayes Factor = 58.4514
Chromosome 6   position 30,946,496  (GRCh37) Explore rs2844680 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.003 0.997
E05.9 Thyrotoxicosis, unspecified
0.000 0.006 0.994
E10 Insulin-dependent diabetes mellitus
0.000 0.035 0.965
E10.9 Without complications
0.000 0.036 0.964
E10-E14 Diabetes mellitus
0.000 0.041 0.959
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.047 0.953
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.108 0.892
E14 Unspecified diabetes mellitus
0.000 0.115 0.885
L40.0 Psoriasis vulgaris
0.000 0.125 0.875
E10.1 With ketoacidosis
0.000 0.128 0.872
E10.3 With ophthalmic complications
0.000 0.158 0.842
E10.2 With renal complications
0.000 0.161 0.839
E14.3 With ophthalmic complications
0.000 0.164 0.836
E10.4 With neurological complications
0.000 0.181 0.819
E07 Other disorders of thyroid
0.000 0.198 0.802
E50-E64 Other nutritional deficiencies
0.000 0.207 0.793
L40.1 Generalised pustular psoriasis
0.000 0.227 0.773
E03.8 Other specified hypothyroidism
0.000 0.244 0.756
L40.4 Guttate psoriasis
0.000 0.246 0.754
E14.8 With unspecified complications
0.000 0.250 0.750
E10.8 With unspecified complications
0.000 0.250 0.750
E14.2 Withrenal complications
0.000 0.282 0.718
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.302 0.698
E03.1 Congenital hypothyroidism without goitre
0.000 0.306 0.694
E14.1 With ketoacidosis
0.000 0.307 0.693
E10.7 With multiple complications
0.000 0.308 0.692
E12 Malnutrition-related diabetes mellitus
0.000 0.312 0.688
E55 Vitamin D deficiency
0.000 0.316 0.684
E61 Deficiency of other nutrient elements
0.000 0.326 0.674
E06 Thyroiditis
0.000 0.334 0.666
E10.0 With coma
0.000 0.341 0.659
E05.8 Other thyrotoxicosis
0.000 0.343 0.657
E07.9 Disorder of thyroid, unspecified
0.000 0.345 0.655
L40.8 Other psoriasis
0.000 0.348 0.652
E14.7 With multiple complications
0.000 0.365 0.635
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.386 0.614
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.387 0.613
E14.5 With peripheral circulatory complications
0.000 0.387 0.613
E14.4 With neurological complications
0.000 0.388 0.612
E55.9 Vitamin D deficiency, unspecified
0.000 0.393 0.607
E14.6 With other specified complications
0.000 0.395 0.605
E10.6 With other specified complications
0.000 0.401 0.598
L40.3 Pustulosis palmaris et plantaris
0.000 0.406 0.594
E61.1 Iron deficiency
0.000 0.412 0.588
E07.8 Other specified disorders of thyroid
0.000 0.418 0.582
E51 Thiamine deficiency
0.000 0.423 0.577
E13 Other specified diabetes mellitus
0.000 0.425 0.575
E07.1 Dyshormogenetic goitre
0.000 0.425 0.575
E07.0 Hypersecretion of calcitonin
0.000 0.425 0.575
E06.3 Autoimmune thyroiditis
0.000 0.430 0.570
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.431 0.569
E63 Other nutritional deficiencies
0.000 0.431 0.569
E50 Vitamin A deficiency
0.000 0.431 0.569
E60 Dietary zinc deficiency
0.000 0.431 0.569
E59 Dietary selenium deficiency
0.000 0.431 0.569
E54 Ascorbic acid deficiency
0.000 0.431 0.569
E52 Niacin deficiency [pellagra]
0.000 0.431 0.569
E14.0 With coma
0.000 0.433 0.567
E56 Other vitamin deficiencies
0.000 0.445 0.555
E16 Other disorders of pancreatic internal secretion
0.000 0.484 0.516
E58 Dietary calcium deficiency
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.497 0.503
E15 Nondiabetic hypoglycaemic coma
0.000 0.499 0.501
E12.9 Without complications
0.000 0.507 0.493
E12.8 With unspecified complications
0.000 0.507 0.493
E12.7 With multiple complications
0.000 0.507 0.493
E12.6 With other specified complications
0.000 0.507 0.493
E12.5 With peripheral circulatory complications
0.000 0.507 0.493
E12.4 With neurological complications
0.000 0.507 0.493
E12.3 With ophthalmic complications
0.000 0.507 0.493
E12.2 With renal complications
0.000 0.507 0.493
E12.1 With ketoacidosis
0.000 0.507 0.493
E12.0 With coma
0.000 0.507 0.493
E55.0 Rickets, active
0.000 0.509 0.491
E61.9 Deficiency of nutrient element, unspecified
0.000 0.517 0.483
E61.8 Deficiency of other specified nutrient elements
0.000 0.517 0.483
E61.7 Deficiency of multiple nutrient elements
0.000 0.517 0.483
E61.6 Vanadium deficiency
0.000 0.517 0.483
E61.5 Molybdenum deficiency
0.000 0.517 0.483
E61.4 Chromium deficiency
0.000 0.517 0.483
E61.3 Manganese deficiency
0.000 0.517 0.483
E61.0 Copper deficiency
0.000 0.517 0.483
E61.2 Magnesium deficiency
0.000 0.517 0.483
E06.5 Other chronic thyroiditis
0.000 0.518 0.482
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.522 0.478
E06.4 Drug-induced thyroiditis
0.000 0.522 0.478
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.522 0.478
E06.0 Acute thyroiditis
0.000 0.522 0.478
E40-E46 Malnutrition
0.000 0.522 0.477
E10.5 With peripheral circulatory complications
0.000 0.534 0.466
M79.6 Pain in limb
0.000 0.543 0.457
M79.62 Pain in limb (Upper arm)
0.000 0.556 0.444
E53 Deficiency of other B group vitamins
0.000 0.559 0.440
E51.2 Wernicke's encephalopathy
0.000 0.578 0.422
K90 Intestinal malabsorption
0.000 0.580 0.420
E13.3 With ophthalmic complications
0.000 0.580 0.420
M79.67 Pain in limb (Ankle and foot)
0.000 0.584 0.416
E06.1 Subacute thyroiditis
0.000 0.586 0.414
E51.9 Thiamine deficiency, unspecified
0.000 0.586 0.414
E51.8 Other manifestations of thiamine deficiency
0.000 0.586 0.414
E51.1 Beriberi
0.000 0.586 0.414
E13.8 With unspecified complications
0.000 0.587 0.412
E13.7 With multiple complications
0.000 0.587 0.412
E13.6 With other specified complications
0.000 0.587 0.412
E13.5 With peripheral circulatory complications
0.000 0.587 0.412
E13.4 With neurological complications
0.000 0.587 0.412
E13.2 With renal complications
0.000 0.587 0.412
E13.1 With ketoacidosis
0.000 0.587 0.412
E13.0 With coma
0.000 0.587 0.412
M79.69 Pain in limb (Site unspecified)
0.000 0.591 0.409
E11 Non-insulin-dependent diabetes mellitus
0.000 0.591 0.409
E50.9 Vitamin A deficiency, unspecified
0.000 0.592 0.408
E50.8 Other manifestations of vitamin A deficiency
0.000 0.592 0.408
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.592 0.408
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.592 0.408
E50.5 Vitamin A deficiency with night blindness
0.000 0.592 0.408
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.592 0.408
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.592 0.408
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.592 0.408
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.592 0.408
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.592 0.408
E63.9 Nutritional deficiency, unspecified
0.000 0.592 0.408
E63.8 Other specified nutritional deficiencies
0.000 0.592 0.408
E63.1 Imbalance of constituents of food intake
0.000 0.592 0.408
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.592 0.408
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.592 0.408
E64.8 Sequelae of other nutritional deficiencies
0.000 0.592 0.408
E64.3 Sequelae of rickets
0.000 0.592 0.408
E64.2 Sequelae of vitamin C deficiency
0.000 0.592 0.408
E64.1 Sequelae of vitamin A deficiency
0.000 0.592 0.408
E64.0 Sequelae of protein-energy malnutrition
0.000 0.592 0.408
E16.2 Hypoglycaemia, unspecified
0.000 0.595 0.405
E56.9 Vitamin deficiency, unspecified
0.000 0.602 0.398
E56.8 Deficiency of other vitamins
0.000 0.602 0.398
E56.0 Deficiency of vitamin E
0.000 0.602 0.398
E56.1 Deficiency of vitamin K
0.000 0.616 0.384
M79.63 Pain in limb (Forearm)
0.000 0.618 0.382
E11.1 With ketoacidosis
0.000 0.623 0.377
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.624 0.376
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.630 0.370
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.630 0.370
E16.4 Abnormal secretion of gastrin
0.000 0.630 0.370
E16.3 Increased secretion of glucagon
0.000 0.630 0.370
M79.60 Pain in limb (Multiple sites)
0.000 0.635 0.365
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.644 0.356
L40-L45 Papulosquamous disorders
0.000 0.650 0.350
M79.64 Pain in limb (Hand)
0.000 0.653 0.347
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.657 0.342
E45 Retarded development following protein-energy malnutrition
0.000 0.657 0.342
E43 Unspecified severe protein-energy malnutrition
0.000 0.657 0.342
E42 Marasmic kwashiorkor
0.000 0.657 0.342
E41 Nutritional marasmus
0.000 0.657 0.342
E40 Kwashiorkor
0.000 0.657 0.342
E11.0 With coma
0.000 0.659 0.341
E16.1 Other hypoglycaemia
0.000 0.665 0.335
E11.6 With other specified complications
0.000 0.666 0.334
E65-E68 Obesity and other hyperalimentation
0.000 0.680 0.320
E53.1 Pyridoxine deficiency
0.000 0.684 0.316
E53.0 Riboflavin deficiency
0.000 0.684 0.316
E14.9 Without complications
0.000 0.686 0.314
E06.9 Thyroiditis, unspecified
0.000 0.691 0.309
K90.3 Pancreatic steatorrhoea
0.000 0.698 0.302
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.698 0.302
K90.1 Tropical sprue
0.000 0.698 0.302
E11.2 With renal complications
0.000 0.701 0.299
E53.9 Vitamin B deficiency, unspecified
0.000 0.704 0.295
E11.7 With multiple complications
0.000 0.707 0.293
E13.9 Without complications
0.000 0.713 0.287
M79.68 Pain in limb (Other)
0.000 0.714 0.286
K90.8 Other intestinal malabsorption
0.000 0.720 0.280
L42 Pityriasis rosea
0.000 0.745 0.254
L44 Other papulosquamous disorders
0.000 0.749 0.251
L41 Parapsoriasis
0.000 0.749 0.251
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.749 0.251
E44.1 Mild protein-energy malnutrition
0.000 0.754 0.245
E44.0 Moderate protein-energy malnutrition
0.000 0.754 0.245
E67 Other hyperalimentation
0.000 0.770 0.229
E68 Sequelae of hyperalimentation
0.000 0.770 0.229
E53.8 Deficiency of other specified B group vitamins
0.000 0.777 0.223
E11.4 With neurological complications
0.000 0.777 0.223
E11.8 With unspecified complications
0.000 0.780 0.220
K90.9 Intestinal malabsorption, unspecified
0.000 0.783 0.217
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.784 0.216
L43 Lichen planus
0.000 0.790 0.210
E11.3 With ophthalmic complications
0.000 0.797 0.203
M45 Ankylosing spondylitis
0.000 0.803 0.197
M79.61 Pain in limb (Shoulder region)
0.000 0.808 0.192
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.812 0.188
Z83.7 Family history of diseases of the digestive system
0.000 0.814 0.186
L41.9 Parapsoriasis, unspecified
0.000 0.820 0.180
L41.8 Other parapsoriasis
0.000 0.820 0.180
L41.5 Retiform parapsoriasis
0.000 0.820 0.180
L41.4 Large plaque parapsoriasis
0.000 0.820 0.180
L41.3 Small plaque parapsoriasis
0.000 0.820 0.180
L41.2 Lymphomatoid papulosis
0.000 0.820 0.180
L41.1 Pityriasis lichenoides chronica
0.000 0.820 0.180
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.820 0.180
L44.9 Papulosquamous disorder, unspecified
0.000 0.820 0.180
L44.8 Other specified papulosquamous disorders
0.000 0.820 0.180
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.820 0.180
L44.3 Lichen ruber moniliformis
0.000 0.820 0.180
L44.2 Lichen striatus
0.000 0.820 0.180
L44.1 Lichen nitidus
0.000 0.820 0.180
L44.0 Pityriasis rubra pilaris
0.000 0.820 0.180
E65 Localised adiposity
0.000 0.830 0.169
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.835 0.165
L43.8 Other lichen planus
0.000 0.835 0.165
E67.8 Other specified hyperalimentation
0.000 0.835 0.165
E67.3 Hypervitaminosis D
0.000 0.835 0.165
E67.2 Megavitamin-B6 syndrome
0.000 0.835 0.165
E67.1 Hypercarotenaemia
0.000 0.835 0.165
E67.0 Hypervitaminosis A
0.000 0.835 0.165
E11.5 With peripheral circulatory complications
0.000 0.837 0.163
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.842 0.158
L43.3 Subacute (active) lichen planus
0.000 0.849 0.151
L43.2 Lichenoid drug reaction
0.000 0.849 0.151
L43.1 Bullous lichen planus
0.000 0.849 0.151
L43.0 Hypertrophic lichen planus
0.000 0.849 0.151
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.858 0.142
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.858 0.142
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.858 0.142
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.858 0.142
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.858 0.142
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.858 0.142
E46 Unspecified protein-energy malnutrition
0.001 0.863 0.136
E20-E35 Disorders of other endocrine glands
0.000 0.877 0.123
Z83 Family history of other specific disorders
0.000 0.877 0.123
L72.0 Epidermal cyst
0.116 0.884 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.891 0.109
L72 Follicular cysts of skin and subcutaneous tissue
0.108 0.892 0.000
L72.1 Trichilemmal cyst
0.104 0.896 0.000
E24 Cushing's syndrome
0.000 0.897 0.103
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.101 0.899 0.000
Z83.5 Family history of eye and ear disorders
0.000 0.899 0.101
E04 Other non-toxic goitre
0.000 0.902 0.098
Z83.6 Family history of diseases of the respiratory system
0.000 0.903 0.097
Z83.1 Family history of other infectious and parasitic diseases
0.000 0.903 0.097
E70-E90 Metabolic disorders
0.000 0.903 0.097
M79.19 Myalgia (Site unspecified)
0.000 0.904 0.096
E25 Adrenogenital disorders
0.000 0.907 0.093
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.907 0.093
E78.5 Hyperlipidaemia, unspecified
0.000 0.909 0.091
M79.1 Myalgia
0.000 0.909 0.091
E31 Polyglandular dysfunction
0.000 0.910 0.090
E34 Other endocrine disorders
0.000 0.911 0.089
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.911 0.089
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.912 0.088
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.912 0.088
E32 Diseases of thymus
0.000 0.912 0.088
E30 Disorders of puberty, not elsewhere classified
0.000 0.912 0.088
Z83.0 Family history of human immunodeficiency virus [HIV]
0.000 0.912 0.088
E78.8 Other disorders of lipoprotein metabolism
0.000 0.912 0.088
E85 Amyloidosis
0.000 0.914 0.086
E24.2 Drug-induced Cushing's syndrome
0.000 0.915 0.085
M79.16 Myalgia (Lower leg)
0.000 0.917 0.083
E78.1 Pure hyperglyceridaemia
0.000 0.917 0.083
E24.0 Pituitary-dependent Cushing's disease
0.000 0.919 0.081
K74.3 Primary biliary cirrhosis
0.000 0.919 0.081
K74 Fibrosis and cirrhosis of liver
0.000 0.920 0.080
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.921 0.079
E23 Hypofunction and other disorders of pituitary gland
0.000 0.921 0.078
K74.6 Other and unspecified cirrhosis of liver
0.000 0.922 0.078
L43.9 Lichen planus, unspecified
0.000 0.922 0.078
E20 Hypoparathyroidism
0.000 0.923 0.077
E24.9 Cushing's syndrome, unspecified
0.000 0.923 0.077
E26 Hyperaldosteronism
0.000 0.925 0.075
E85.9 Amyloidosis, unspecified
0.000 0.925 0.075
L72.2 Steatocystoma multiplex
0.075 0.925 0.000
K72 Hepatic failure, not elsewhere classified
0.000 0.926 0.074
K70-K77 Diseases of liver
0.000 0.926 0.074
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.926 0.074
E24.3 Ectopic ACTH syndrome
0.000 0.926 0.074
E24.1 Nelson's syndrome
0.000 0.926 0.074
E04.0 Non-toxic diffuse goitre
0.000 0.928 0.072
E21.3 Hyperparathyroidism, unspecified
0.000 0.928 0.072
E24.8 Other Cushing's syndrome
0.000 0.928 0.071
K75.4 Autoimmune hepatitis
0.000 0.928 0.072
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.929 0.071
E34.0 Carcinoid syndrome
0.000 0.929 0.071
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.929 0.071
E04.8 Other specified non-toxic goitre
0.000 0.929 0.070
Z83.3 Family history of diabetes mellitus
0.000 0.930 0.070
K72.9 Hepatic failure, unspecified
0.000 0.930 0.070
E77 Disorders of glycoprotein metabolism
0.000 0.930 0.069
E76 Disorders of glycosaminoglycan metabolism
0.000 0.930 0.069
E72 Other disorders of amino-acid metabolism
0.000 0.930 0.069
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.930 0.069
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.930 0.069
E74 Other disorders of carbohydrate metabolism
0.000 0.931 0.069
E28 Ovarian dysfunction
0.000 0.931 0.069
E70 Disorders of aromatic amino-acid metabolism
0.000 0.931 0.068
E84 Cystic fibrosis
0.000 0.931 0.068
E85.4 Organ-limited amyloidosis
0.000 0.932 0.068
K75 Other inflammatory liver diseases
0.000 0.932 0.068
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.932 0.068
K72.0 Acute and subacute hepatic failure
0.000 0.933 0.067
E31.0 Autoimmune polyglandular failure
0.000 0.933 0.067
E23.7 Disorder of pituitary gland, unspecified
0.000 0.933 0.067
E25.9 Adrenogenital disorder, unspecified
0.000 0.933 0.067
E25.8 Other adrenogenital disorders
0.000 0.933 0.067
M79.17 Myalgia (Ankle and foot)
0.000 0.935 0.065
M79.14 Myalgia (Hand)
0.000 0.935 0.065
M79.13 Myalgia (Forearm)
0.000 0.935 0.065
M79.12 Myalgia (Upper arm)
0.000 0.935 0.065
E31.9 Polyglandular dysfunction, unspecified
0.000 0.935 0.065
E31.8 Other polyglandular dysfunction
0.000 0.935 0.065
E31.1 Polyglandular hyperfunction
0.000 0.935 0.065
E21.2 Other hyperparathyroidism
0.000 0.935 0.065
E34.9 Endocrine disorder, unspecified
0.000 0.935 0.065
E85.3 Secondary systemic amyloidosis
0.000 0.936 0.064
E34.5 Androgen resistance syndrome
0.000 0.936 0.064
E34.4 Constitutional tall stature
0.000 0.936 0.064
E34.3 Short stature, not elsewhere classified
0.000 0.936 0.064
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.936 0.064
E34.1 Other hypersecretion of intestinal hormones
0.000 0.936 0.064
E78.3 Hyperchylomicronaemia
0.000 0.936 0.064
E21.4 Other specified disorders of parathyroid gland
0.000 0.936 0.064
E78.6 Lipoprotein deficiency
0.000 0.936 0.064
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.000 0.936 0.064
M79.3 Panniculitis, unspecified
0.000 0.936 0.064
E30.9 Disorder of puberty, unspecified
0.000 0.936 0.063
E30.8 Other disorders of puberty
0.000 0.936 0.063
E30.1 Precocious puberty
0.000 0.936 0.063
E30.0 Delayed puberty
0.000 0.936 0.063
E32.9 Disease of thymus, unspecified
0.000 0.936 0.063
E32.8 Other diseases of thymus
0.000 0.936 0.063
E32.1 Abscess of thymus
0.000 0.936 0.063
E32.0 Persistent hyperplasia of thymus
0.000 0.936 0.063
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.936 0.063
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.936 0.063
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.936 0.063
E79 Disorders of purine and pyrimidine metabolism
0.000 0.936 0.063
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.938 0.062
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.938 0.062
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.938 0.062
M79.9 Soft tissue disorder, unspecified
0.000 0.939 0.061
E85.8 Other amyloidosis
0.000 0.939 0.061
E29 Testicular dysfunction
0.000 0.939 0.060
M79.18 Myalgia (Other)
0.000 0.940 0.060
M79.11 Myalgia (Shoulder region)
0.000 0.940 0.060
K72.1 Chronic hepatic failure
0.000 0.941 0.059
K74.5 Biliary cirrhosis, unspecified
0.000 0.941 0.059
E73 Lactose intolerance
0.000 0.941 0.058
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.941 0.059
E23.2 Diabetes insipidus
0.000 0.942 0.058
K73 Chronic hepatitis, not elsewhere classified
0.000 0.942 0.058
E80.2 Other porphyria
0.000 0.942 0.058
K75.8 Other specified inflammatory liver diseases
0.000 0.942 0.058
K74.4 Secondary biliary cirrhosis
0.000 0.942 0.057
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.942 0.057
K74.1 Hepatic sclerosis
0.000 0.942 0.057
M79.4 Hypertrophy of (infrapatellar) fat pad
0.000 0.943 0.057
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.943 0.056
E23.1 Drug-induced hypopituitarism
0.000 0.943 0.056
K71 Toxic liver disease
0.000 0.944 0.056
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.944 0.056
E23.6 Other disorders of pituitary gland
0.000 0.944 0.055
E20.8 Other hypoparathyroidism
0.000 0.944 0.055
E20.1 Pseudohypoparathyroidism
0.000 0.944 0.055
E20.0 Idiopathic hypoparathyroidism
0.000 0.944 0.055
E34.8 Other specified endocrine disorders
0.000 0.945 0.055
E88 Other metabolic disorders
0.000 0.945 0.055
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.946 0.054
E26.8 Other hyperaldosteronism
0.000 0.946 0.054
E26.1 Secondary hyperaldosteronism
0.000 0.946 0.054
K77 Liver disorders in diseases classified elsewhere
0.000 0.946 0.053
E78.2 Mixed hyperlipidaemia
0.000 0.947 0.053
K70 Alcoholic liver disease
0.000 0.947 0.053
E75.5 Other lipid storage disorders
0.000 0.947 0.052
M79.10 Myalgia (Multiple sites)
0.000 0.948 0.052
E22 Hyperfunction of pituitary gland
0.000 0.948 0.052
E80.6 Other disorders of bilirubin metabolism
0.000 0.949 0.051
E75.6 Lipid storage disorder, unspecified
0.000 0.949 0.051
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.949 0.051
E75.3 Sphingolipidosis, unspecified
0.000 0.949 0.051
E75.2 Other sphingolipidosis
0.000 0.949 0.051
E75.1 Other gangliosidosis
0.000 0.949 0.051
E75.0 GM2 gangliosidosis
0.000 0.949 0.051
E26.0 Primary hyperaldosteronism
0.000 0.949 0.050
E71.3 Disorders of fatty-acid metabolism
0.000 0.950 0.050
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.950 0.050
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.950 0.050
E71.0 Maple-syrup-urine disease
0.000 0.950 0.050
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.950 0.050
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.950 0.050
E72.5 Disorders of glycine metabolism
0.000 0.950 0.050
E72.4 Disorders of ornithine metabolism
0.000 0.950 0.050
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.950 0.050
E72.2 Disorders of urea cycle metabolism
0.000 0.950 0.050
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.950 0.050
E72.0 Disorders of amino-acid transport
0.000 0.950 0.050
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.950 0.050
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.950 0.050
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.950 0.050
E76.2 Other mucopolysaccharidoses
0.000 0.950 0.050
E76.1 Mucopolysaccharidosis, type II
0.000 0.950 0.050
E76.0 Mucopolysaccharidosis, type I
0.000 0.950 0.050
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.950 0.050
E77.8 Other disorders of glycoprotein metabolism
0.000 0.950 0.050
E77.1 Defects in glycoprotein degradation
0.000 0.950 0.050
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.950 0.050
E74.0 Glycogen storage disease
0.000 0.950 0.050
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.950 0.050
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.950 0.050
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.950 0.050
E74.2 Disorders of galactose metabolism
0.000 0.950 0.050
E74.1 Disorders of fructose metabolism
0.000 0.950 0.050
E28.9 Ovarian dysfunction, unspecified
0.000 0.950 0.050
E28.8 Other ovarian dysfunction
0.000 0.950 0.050
E28.1 Androgen excess
0.000 0.950 0.050
E28.0 Oestrogen excess
0.000 0.950 0.050
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.950 0.050
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.950 0.049
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.950 0.049
E70.2 Disorders of tyrosine metabolism
0.000 0.950 0.049
E70.1 Other hyperphenylalaninaemias
0.000 0.950 0.049
E70.0 Classical phenylketonuria
0.000 0.950 0.049
E84.8 Cystic fibrosis with other manifestations
0.000 0.951 0.049
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.951 0.049
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.951 0.049
K75.2 Nonspecific reactive hepatitis
0.000 0.951 0.049
K75.1 Phlebitis of portal vein
0.000 0.951 0.049
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.951 0.049
E80.5 Crigler-Najjar syndrome
0.000 0.951 0.049
E80.3 Defects of catalase and peroxydase
0.000 0.951 0.049
E80.0 Hereditary erythropoietic porphyria
0.000 0.951 0.049
E80.1 Porphyria cutanea tarda
0.000 0.951 0.049
E70.3 Albinism
0.000 0.951 0.048
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.951 0.048
E84.9 Cystic fibrosis, unspecified
0.000 0.952 0.048
M79.96 Soft tissue disorder, unspecified (Lower leg)
0.000 0.952 0.048
E78.4 Other hyperlipidaemia
0.000 0.952 0.048
M79.8 Other specified soft tissue disorders
0.000 0.952 0.048
E88.8 Other specified metabolic disorders
0.000 0.952 0.048
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.000 0.953 0.047
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.953 0.047
E28.3 Primary ovarian failure
0.000 0.954 0.046
E66 Obesity
0.000 0.954 0.046
E26.9 Hyperaldosteronism, unspecified
0.000 0.954 0.046
M79.39 Panniculitis, unspecified (Site unspecified)
0.000 0.954 0.046
M79.38 Panniculitis, unspecified (Other)
0.000 0.954 0.046
M79.37 Panniculitis, unspecified (Ankle and foot)
0.000 0.954 0.046
M79.36 Panniculitis, unspecified (Lower leg)
0.000 0.954 0.046
M79.35 Panniculitis, unspecified (Pelvic region and thigh)
0.000 0.954 0.046
M79.34 Panniculitis, unspecified (Hand)
0.000 0.954 0.046
M79.33 Panniculitis, unspecified (Forearm)
0.000 0.954 0.046
M79.32 Panniculitis, unspecified (Upper arm)
0.000 0.954 0.046
M79.31 Panniculitis, unspecified (Shoulder region)
0.000 0.954 0.046
M79.30 Panniculitis, unspecified (Multiple sites)
0.000 0.954 0.046
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.954 0.046
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.954 0.046
E79.1 Lesch-Nyhan syndrome
0.000 0.954 0.046
K71.0 Toxic liver disease with cholestasis
0.000 0.955 0.045
M79.99 Soft tissue disorder, unspecified (Site unspecified)
0.000 0.955 0.045
K90-K93 Other diseases of the digestive system
0.000 0.955 0.045
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.045 0.955 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.955 0.045
M79.98 Soft tissue disorder, unspecified (Other)
0.000 0.955 0.045
M79.97 Soft tissue disorder, unspecified (Ankle and foot)
0.000 0.956 0.044
M79.93 Soft tissue disorder, unspecified (Forearm)
0.000 0.956 0.044
M79.92 Soft tissue disorder, unspecified (Upper arm)
0.000 0.956 0.044
M79.91 Soft tissue disorder, unspecified (Shoulder region)
0.000 0.956 0.044
M79.90 Soft tissue disorder, unspecified (Multiple sites)
0.000 0.956 0.044
E20.9 Hypoparathyroidism, unspecified
0.000 0.956 0.044
M79.15 Myalgia (Pelvic region and thigh)
0.000 0.956 0.044
E29.9 Testicular dysfunction, unspecified
0.000 0.956 0.043
E29.8 Other testicular dysfunction
0.000 0.956 0.043
E29.0 Testicular hyperfunction
0.000 0.956 0.043
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.044 0.956 0.000
K70.1 Alcoholic hepatitis
0.000 0.957 0.043
M07.3 Other psoriatic arthropathies
0.000 0.957 0.043
E88.9 Metabolic disorder, unspecified
0.000 0.957 0.043
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)
0.000 0.957 0.042
E73.8 Other lactose intolerance
0.000 0.958 0.042

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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