TreeWAS – Variant ID: rs2844729

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
K90 Intestinal malabsorption	0.000	0.079	0.921
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.154	0.846
K90.9 Intestinal malabsorption, unspecified	0.000	0.168	0.832
K90.8 Other intestinal malabsorption	0.000	0.253	0.747
K90.3 Pancreatic steatorrhoea	0.000	0.340	0.660
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.340	0.660
K90.1 Tropical sprue	0.000	0.340	0.660
E03 Other hypothyroidism	0.000	0.442	0.558
E03.8 Other specified hypothyroidism	0.000	0.556	0.444
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.560	0.440
E03.5 Myxoedema coma	0.000	0.600	0.400
E03.4 Atrophy of thyroid (acquired)	0.000	0.600	0.400
E03.3 Postinfectious hypothyroidism	0.000	0.600	0.400
E03.1 Congenital hypothyroidism without goitre	0.000	0.615	0.385
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.644	0.356
E00-E07 Disorders of thyroid gland	0.000	0.858	0.142
M35.0 Sicca syndrome [Sjogren]	0.000	0.873	0.127
E06 Thyroiditis	0.000	0.882	0.118
E07 Other disorders of thyroid	0.000	0.888	0.112
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.890	0.110
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.898	0.102
E00 Congenital iodine-deficiency syndrome	0.000	0.898	0.102
E06.3 Autoimmune thyroiditis	0.000	0.901	0.099
E07.8 Other specified disorders of thyroid	0.000	0.908	0.092
E06.9 Thyroiditis, unspecified	0.000	0.911	0.089
E06.5 Other chronic thyroiditis	0.000	0.915	0.085
E06.4 Drug-induced thyroiditis	0.000	0.915	0.085
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.915	0.085
E06.0 Acute thyroiditis	0.000	0.915	0.085
E06.1 Subacute thyroiditis	0.000	0.917	0.083
E07.1 Dyshormogenetic goitre	0.000	0.920	0.080
E07.0 Hypersecretion of calcitonin	0.000	0.920	0.080
E07.9 Disorder of thyroid, unspecified	0.000	0.924	0.076
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.926	0.073
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.926	0.073
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.926	0.073
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.926	0.073
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.926	0.073
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.926	0.073
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.926	0.073
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.926	0.073
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.938	0.062
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.054	0.946	0.000
K90-K93 Other diseases of the digestive system	0.000	0.947	0.053
G25.8 Other specified extrapyramidal and movement disorders	0.045	0.955	0.000
E05.5 Thyroid crisis or storm	0.000	0.955	0.045
E05.4 Thyrotoxicosis factitia	0.000	0.955	0.045
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.955	0.045
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.955	0.045
G25 Other extrapyramidal and movement disorders	0.040	0.960	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.960	0.040
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.960	0.039
E05.9 Thyrotoxicosis, unspecified	0.000	0.961	0.039
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.962	0.038
G24 Dystonia	0.036	0.964	0.000
G20-G26 Extrapyramidal and movement disorders	0.036	0.964	0.000
E05.8 Other thyrotoxicosis	0.000	0.964	0.036
M35 Other systemic involvement of connective tissue	0.000	0.966	0.034
G25.9 Extrapyramidal and movement disorder, unspecified	0.033	0.967	0.000
G21 Secondary Parkinsonism	0.033	0.967	0.000
G24.8 Other dystonia	0.032	0.968	0.000
G24.9 Dystonia, unspecified	0.032	0.968	0.000
G25.1 Drug-induced tremor	0.031	0.969	0.000
G25.5 Other chorea	0.031	0.969	0.000
G25.0 Essential tremor	0.031	0.969	0.000
G24.3 Spasmodic torticollis	0.031	0.969	0.000
E83 Disorders of mineral metabolism	0.029	0.971	0.000
M35.2 Behcet's disease	0.000	0.971	0.029
G25.6 Drug-induced tics and other tics of organic origin	0.029	0.971	0.000
G25.4 Drug-induced chorea	0.029	0.971	0.000
G23 Other degenerative diseases of basal ganglia	0.029	0.971	0.000
G21.9 Secondary Parkinsonism, unspecified	0.028	0.972	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.972	0.028
K93.1 Megacolon in Chagas' disease	0.000	0.972	0.028
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.972	0.028
G24.0 Drug-induced dystonia	0.028	0.972	0.000
G24.1 Idiopathic familial dystonia	0.028	0.972	0.000
G24.5 Blepharospasm	0.027	0.973	0.000
G24.4 Idiopathic orofacial dystonia	0.026	0.974	0.000
G24.2 Idiopathic nonfamilial dystonia	0.026	0.974	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.026	0.974	0.000
G22 Parkinsonism in diseases classified elsewhere	0.026	0.974	0.000
G21.0 Malignant neuroleptic syndrome	0.026	0.974	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.025	0.975	0.000
G21.4 Vascular parkinsonism	0.025	0.975	0.000
M35.8 Other specified systemic involvement of connective tissue	0.000	0.975	0.025
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.976	0.024
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.976	0.024
M35.5 Multifocal fibrosclerosis	0.000	0.976	0.024
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.976	0.024
G21.8 Other secondary Parkinsonism	0.024	0.976	0.000
G21.3 Postencephalitic Parkinsonism	0.024	0.976	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.024	0.976	0.000
G25.3 Myoclonus	0.023	0.977	0.000
M35.7 Hypermobility syndrome	0.000	0.977	0.023
G23.8 Other specified degenerative diseases of basal ganglia	0.022	0.977	0.000
M35.1 Other overlap syndromes	0.000	0.978	0.022
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.022	0.978	0.000
E83.8 Other disorders of mineral metabolism	0.021	0.979	0.000
E83.2 Disorders of zinc metabolism	0.021	0.979	0.000
E83.0 Disorders of copper metabolism	0.021	0.979	0.000
G25.2 Other specified forms of tremor	0.021	0.979	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.021	0.979	0.000
G23.3 Multiple system atrophy, cerebellar type	0.021	0.979	0.000
G23.2 Striatonigral degeneration	0.021	0.979	0.000
G23.0 Hallervorden-Spatz disease	0.021	0.979	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.021	0.979	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.021	0.979	0.000
E04 Other non-toxic goitre	0.000	0.981	0.019
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.982	0.018
E04.0 Non-toxic diffuse goitre	0.000	0.986	0.014
M47.82 Other spondylosis (Cervical region)	0.014	0.986	0.000
E04.8 Other specified non-toxic goitre	0.000	0.986	0.014
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.013	0.987	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.012	0.988	0.000
G20 Parkinson's disease	0.012	0.988	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.011	0.989	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.011	0.989	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.011	0.989	0.000
I83 Varicose veins of lower extremities	0.010	0.990	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.010	0.990	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.010	0.990	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.010	0.990	0.000
E83.3 Disorders of phosphorus metabolism	0.009	0.990	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.990	0.010
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.009	0.991	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.009	0.991	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.009	0.991	0.000
X23.9 Unspecified place	0.000	0.992	0.008
N05.9 Unspecified	0.000	0.992	0.008
E20-E35 Disorders of other endocrine glands	0.000	0.992	0.008
E22 Hyperfunction of pituitary gland	0.000	0.992	0.008
E50-E64 Other nutritional deficiencies	0.000	0.992	0.008
I47.2 Ventricular tachycardia	0.000	0.992	0.008
G57.6 Lesion of plantar nerve	0.008	0.992	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.007	0.992	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.993	0.007
E23 Hypofunction and other disorders of pituitary gland	0.000	0.993	0.007
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.993	0.007
E55 Vitamin D deficiency	0.000	0.993	0.007
E55.9 Vitamin D deficiency, unspecified	0.000	0.993	0.007
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.993	0.007
E22.1 Hyperprolactinaemia	0.000	0.993	0.007
E23.2 Diabetes insipidus	0.000	0.993	0.007
E27 Other disorders of adrenal gland	0.000	0.993	0.007
E27.1 Primary adrenocortical insufficiency	0.000	0.993	0.007
E24 Cushing's syndrome	0.000	0.993	0.007
E10.2 With renal complications	0.000	0.993	0.007
F05.9 Delirium, unspecified	0.000	0.993	0.007
E58 Dietary calcium deficiency	0.000	0.993	0.006
E04.2 Non-toxic multinodular goitre	0.000	0.993	0.007
N05 Unspecified nephritic syndrome	0.000	0.994	0.006
Z57.2 Occupational exposure to dust	0.006	0.994	0.000
E51 Thiamine deficiency	0.000	0.994	0.006
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.994	0.006
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.994	0.006
E32 Diseases of thymus	0.000	0.994	0.006
E31 Polyglandular dysfunction	0.000	0.994	0.006
E30 Disorders of puberty, not elsewhere classified	0.000	0.994	0.006
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.006	0.994	0.000
E10.9 Without complications	0.000	0.994	0.006
E21.0 Primary hyperparathyroidism	0.000	0.994	0.006
E23.7 Disorder of pituitary gland, unspecified	0.000	0.994	0.006
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.994	0.006
E22.8 Other hyperfunction of pituitary gland	0.000	0.994	0.006
E23.0 Hypopituitarism	0.000	0.994	0.006
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.994	0.006
E63 Other nutritional deficiencies	0.000	0.994	0.006
E50 Vitamin A deficiency	0.000	0.994	0.006
E60 Dietary zinc deficiency	0.000	0.994	0.006
E59 Dietary selenium deficiency	0.000	0.994	0.006
E52 Niacin deficiency [pellagra]	0.000	0.994	0.006
K40 Inguinal hernia	0.006	0.994	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.994	0.006
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.994	0.006
E27.2 Addisonian crisis	0.000	0.994	0.006
N05.8 Other	0.000	0.994	0.006
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.994	0.006
N05.2 Diffuse membranous glomerulonephritis	0.000	0.994	0.006
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.994	0.005
E23.1 Drug-induced hypopituitarism	0.000	0.994	0.005
E15 Nondiabetic hypoglycaemic coma	0.000	0.994	0.005
E55.0 Rickets, active	0.000	0.994	0.005
E10 Insulin-dependent diabetes mellitus	0.000	0.994	0.006
E54 Ascorbic acid deficiency	0.000	0.994	0.005
X23 Contact with hornets, wasps and bees	0.000	0.994	0.005
E40-E46 Malnutrition	0.000	0.994	0.005
E56 Other vitamin deficiencies	0.000	0.995	0.005
E24.9 Cushing's syndrome, unspecified	0.000	0.995	0.005
E20 Hypoparathyroidism	0.000	0.995	0.005
E10.3 With ophthalmic complications	0.000	0.995	0.005
E25 Adrenogenital disorders	0.000	0.995	0.005
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.995	0.005
E10-E14 Diabetes mellitus	0.000	0.995	0.005
E21.2 Other hyperparathyroidism	0.000	0.995	0.005
E24.8 Other Cushing's syndrome	0.000	0.995	0.005
E24.0 Pituitary-dependent Cushing's disease	0.000	0.995	0.005
E21.4 Other specified disorders of parathyroid gland	0.000	0.995	0.005
E27.5 Adrenomedullary hyperfunction	0.000	0.995	0.005
E27.0 Other adrenocortical overactivity	0.000	0.995	0.005
E24.2 Drug-induced Cushing's syndrome	0.000	0.995	0.005
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.995	0.005
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.995	0.005
E24.3 Ectopic ACTH syndrome	0.000	0.995	0.005
E24.1 Nelson's syndrome	0.000	0.995	0.005
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.995	0.005
I44.2 Atrioventricular block, complete	0.005	0.995	0.000
E51.2 Wernicke's encephalopathy	0.000	0.995	0.005
E23.6 Other disorders of pituitary gland	0.000	0.995	0.005
E26 Hyperaldosteronism	0.000	0.995	0.005
E27.9 Disorder of adrenal gland, unspecified	0.000	0.995	0.005
N05.1 Focal and segmental glomerular lesions	0.000	0.995	0.005
E28 Ovarian dysfunction	0.000	0.995	0.005
X23.0 Home	0.000	0.995	0.005
E61 Deficiency of other nutrient elements	0.000	0.995	0.005
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.995	0.005
E04.9 Non-toxic goitre, unspecified	0.000	0.995	0.005
N05.6 Dense deposit disease	0.000	0.995	0.005
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.995	0.005
N05.0 Minor glomerular abnormality	0.000	0.995	0.005
E51.9 Thiamine deficiency, unspecified	0.000	0.995	0.004
E51.8 Other manifestations of thiamine deficiency	0.000	0.995	0.004
E51.1 Beriberi	0.000	0.995	0.004
F05.0 Delirium not superimposed on dementia, so described	0.000	0.995	0.005
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.995	0.005
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.005	0.995	0.000
E30.9 Disorder of puberty, unspecified	0.000	0.995	0.004
E30.8 Other disorders of puberty	0.000	0.995	0.004
E30.1 Precocious puberty	0.000	0.995	0.004
E30.0 Delayed puberty	0.000	0.995	0.004
E31.9 Polyglandular dysfunction, unspecified	0.000	0.995	0.004
E31.8 Other polyglandular dysfunction	0.000	0.995	0.004
E31.1 Polyglandular hyperfunction	0.000	0.995	0.004
E31.0 Autoimmune polyglandular failure	0.000	0.995	0.004
E32.9 Disease of thymus, unspecified	0.000	0.995	0.004
E32.8 Other diseases of thymus	0.000	0.995	0.004
E32.1 Abscess of thymus	0.000	0.995	0.004
E32.0 Persistent hyperplasia of thymus	0.000	0.995	0.004
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.995	0.004
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.995	0.004
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.995	0.004
K75.4 Autoimmune hepatitis	0.000	0.995	0.005
M22.2 Patellofemoral disorders	0.000	0.995	0.005
E16.1 Other hypoglycaemia	0.000	0.995	0.004
K81.0 Acute cholecystitis	0.005	0.995	0.000
E29 Testicular dysfunction	0.000	0.995	0.004
G90 Disorders of autonomic nervous system	0.000	0.995	0.005
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.995	0.004
E50.9 Vitamin A deficiency, unspecified	0.000	0.996	0.004
E50.8 Other manifestations of vitamin A deficiency	0.000	0.996	0.004
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.996	0.004
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.996	0.004
E50.5 Vitamin A deficiency with night blindness	0.000	0.996	0.004
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.996	0.004
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.996	0.004
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.996	0.004
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.996	0.004
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.996	0.004
E63.9 Nutritional deficiency, unspecified	0.000	0.996	0.004
E63.8 Other specified nutritional deficiencies	0.000	0.996	0.004
E63.1 Imbalance of constituents of food intake	0.000	0.996	0.004
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.996	0.004
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.996	0.004
E64.8 Sequelae of other nutritional deficiencies	0.000	0.996	0.004
E64.3 Sequelae of rickets	0.000	0.996	0.004
E64.2 Sequelae of vitamin C deficiency	0.000	0.996	0.004
E64.1 Sequelae of vitamin A deficiency	0.000	0.996	0.004
E64.0 Sequelae of protein-energy malnutrition	0.000	0.996	0.004
E21.3 Hyperparathyroidism, unspecified	0.000	0.996	0.004
E22.0 Acromegaly and pituitary gigantism	0.000	0.996	0.004
K40.1 Bilateral inguinal hernia, with gangrene	0.004	0.996	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.996	0.004
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.996	0.004
E16.4 Abnormal secretion of gastrin	0.000	0.996	0.004
E16.3 Increased secretion of glucagon	0.000	0.996	0.004
G90.3 Multisystem degeneration	0.000	0.996	0.004
G90.2 Horner's syndrome	0.000	0.996	0.004
X23.7 Farm	0.000	0.996	0.004
X23.6 Industrial and construction area	0.000	0.996	0.004
X23.5 Trade and service area	0.000	0.996	0.004
X23.4 Street and highway	0.000	0.996	0.004
X23.3 Sports and athletics area	0.000	0.996	0.004
X23.2 School, other institution and public administrative area	0.000	0.996	0.004
X23.1 Residential institution	0.000	0.996	0.004
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.996	0.004
E45 Retarded development following protein-energy malnutrition	0.000	0.996	0.004
E43 Unspecified severe protein-energy malnutrition	0.000	0.996	0.004
E42 Marasmic kwashiorkor	0.000	0.996	0.004
E41 Nutritional marasmus	0.000	0.996	0.004
E40 Kwashiorkor	0.000	0.996	0.004
E56.9 Vitamin deficiency, unspecified	0.000	0.996	0.004
E56.8 Deficiency of other vitamins	0.000	0.996	0.004
E56.0 Deficiency of vitamin E	0.000	0.996	0.004
E83.5 Disorders of calcium metabolism	0.004	0.996	0.000
E20.8 Other hypoparathyroidism	0.000	0.996	0.004
E20.1 Pseudohypoparathyroidism	0.000	0.996	0.004
E20.0 Idiopathic hypoparathyroidism	0.000	0.996	0.004
H01.0 Blepharitis	0.004	0.996	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.996	0.004
E25.8 Other adrenogenital disorders	0.000	0.996	0.004
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.996	0.004
X23.8 Other specified place	0.000	0.996	0.004
E12 Malnutrition-related diabetes mellitus	0.000	0.996	0.004
T17.2 Foreign body in pharynx	0.004	0.996	0.000
E83.4 Disorders of magnesium metabolism	0.004	0.996	0.001
F05.8 Other delirium	0.000	0.996	0.004
E53 Deficiency of other B group vitamins	0.000	0.996	0.004
C77.9 Lymph node, unspecified	0.004	0.996	0.000
E10.7 With multiple complications	0.000	0.996	0.004
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.004	0.996	0.000
E56.1 Deficiency of vitamin K	0.000	0.996	0.004
E26.8 Other hyperaldosteronism	0.000	0.996	0.004
E26.1 Secondary hyperaldosteronism	0.000	0.996	0.004
E10.4 With neurological complications	0.000	0.996	0.004
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.004	0.996	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.996	0.004
E28.8 Other ovarian dysfunction	0.000	0.996	0.004
E28.1 Androgen excess	0.000	0.996	0.004
E28.0 Oestrogen excess	0.000	0.996	0.004
N05.7 Diffuse crescentic glomerulonephritis	0.000	0.996	0.004
E13 Other specified diabetes mellitus	0.000	0.996	0.004
I83.1 Varicose veins of lower extremities with inflammation	0.004	0.996	0.000
M00.9 Pyogenic arthritis, unspecified	0.004	0.996	0.000
E61.9 Deficiency of nutrient element, unspecified	0.000	0.996	0.004
E61.8 Deficiency of other specified nutrient elements	0.000	0.996	0.004
E61.7 Deficiency of multiple nutrient elements	0.000	0.996	0.004
E61.6 Vanadium deficiency	0.000	0.996	0.004
E61.5 Molybdenum deficiency	0.000	0.996	0.004
E61.4 Chromium deficiency	0.000	0.996	0.004
E61.3 Manganese deficiency	0.000	0.996	0.004
E61.0 Copper deficiency	0.000	0.996	0.004
E26.9 Hyperaldosteronism, unspecified	0.000	0.996	0.003
T17.8 Foreign body in other and multiple parts of respiratory tract	0.004	0.996	0.000
E10.6 With other specified complications	0.000	0.996	0.004
G31.8 Other specified degenerative diseases of nervous system	0.000	0.996	0.004
E28.3 Primary ovarian failure	0.000	0.996	0.003
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.004	0.996	0.000
G90.8 Other disorders of autonomic nervous system	0.000	0.996	0.004
S62.20 Fracture of first metacarpal bone (closed)	0.004	0.996	0.000
T17 Foreign body in respiratory tract	0.004	0.996	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.996	0.003
E29.9 Testicular dysfunction, unspecified	0.000	0.996	0.003
E29.8 Other testicular dysfunction	0.000	0.996	0.003
E29.0 Testicular hyperfunction	0.000	0.996	0.003
F05.1 Delirium superimposed on dementia	0.000	0.996	0.003
G90.4 Autonomic dysreflexia	0.000	0.996	0.003
G90.1 Familial dysautonomia [Riley-Day]	0.000	0.996	0.003
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.997	0.003
E61.2 Magnesium deficiency	0.000	0.997	0.003
K74.5 Biliary cirrhosis, unspecified	0.000	0.997	0.003
F25.9 Schizoaffective disorder, unspecified	0.000	0.997	0.003
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
E10.8 With unspecified complications	0.000	0.997	0.003
E44.1 Mild protein-energy malnutrition	0.000	0.997	0.003
E44.0 Moderate protein-energy malnutrition	0.000	0.997	0.003
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.003	0.997	0.000
M22.8 Other disorders of patella	0.000	0.997	0.003
M22.3 Other derangements of patella	0.000	0.997	0.003
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.003	0.997	0.000
M22 Disorders of patella	0.000	0.997	0.003
E12.9 Without complications	0.000	0.997	0.003
E12.8 With unspecified complications	0.000	0.997	0.003
E12.7 With multiple complications	0.000	0.997	0.003
E12.6 With other specified complications	0.000	0.997	0.003
E12.5 With peripheral circulatory complications	0.000	0.997	0.003
E12.4 With neurological complications	0.000	0.997	0.003
E12.3 With ophthalmic complications	0.000	0.997	0.003
E12.2 With renal complications	0.000	0.997	0.003
E12.1 With ketoacidosis	0.000	0.997	0.003
E12.0 With coma	0.000	0.997	0.003
E34 Other endocrine disorders	0.001	0.997	0.003
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
E53.1 Pyridoxine deficiency	0.000	0.997	0.003
E53.0 Riboflavin deficiency	0.000	0.997	0.003
E13.3 With ophthalmic complications	0.000	0.997	0.003
D52.9 Folate deficiency anaemia, unspecified	0.000	0.997	0.003
I84.3 External thrombosed haemorrhoids	0.003	0.997	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
M35.3 Polymyalgia rheumatica	0.000	0.997	0.003
E10.1 With ketoacidosis	0.000	0.997	0.003
E61.1 Iron deficiency	0.000	0.997	0.003
L50.1 Idiopathic urticaria	0.000	0.997	0.003
E10.0 With coma	0.000	0.997	0.003
S01.0 Open wound of scalp	0.000	0.997	0.003
E13.8 With unspecified complications	0.000	0.997	0.003
E13.7 With multiple complications	0.000	0.997	0.003
E13.6 With other specified complications	0.000	0.997	0.003
E13.5 With peripheral circulatory complications	0.000	0.997	0.003
E13.4 With neurological complications	0.000	0.997	0.003
E13.2 With renal complications	0.000	0.997	0.003
E13.1 With ketoacidosis	0.000	0.997	0.003
E13.0 With coma	0.000	0.997	0.003
M00.98 Pyogenic arthritis, unspecified (Other)	0.003	0.997	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.997	0.003
I47 Paroxysmal tachycardia	0.000	0.997	0.003
E26.0 Primary hyperaldosteronism	0.000	0.997	0.003
L50 Urticaria	0.000	0.997	0.003
E27.8 Other specified disorders of adrenal gland	0.000	0.997	0.003
I47.0 Reentry ventricular arrhythmia	0.000	0.997	0.003
X41.9 Unspecified place	0.003	0.997	0.000
O30.0 Twin pregnancy	0.003	0.997	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.003	0.997	0.000
T17.4 Foreign body in trachea	0.003	0.997	0.000
T17.1 Foreign body in nostril	0.003	0.997	0.000
T17.0 Foreign body in nasal sinus	0.003	0.997	0.000
C81.9 Hodgkin's disease, unspecified	0.000	0.997	0.003
E10.5 With peripheral circulatory complications	0.000	0.997	0.003
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.997	0.003
G57 Mononeuropathies of lower limb	0.003	0.997	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.997	0.003
M22.0 Recurrent dislocation of patella	0.000	0.997	0.003
T17.3 Foreign body in larynx	0.003	0.997	0.000
T17.5 Foreign body in bronchus	0.003	0.997	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.997	0.003
L50.8 Other urticaria	0.000	0.997	0.003
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.997	0.002
L50.9 Urticaria, unspecified	0.000	0.997	0.003
L50.0 Allergic urticaria	0.000	0.997	0.003
F25.1 Schizoaffective disorder, depressive type	0.000	0.997	0.003
M22.1 Recurrent subluxation of patella	0.000	0.997	0.002
E65-E68 Obesity and other hyperalimentation	0.000	0.997	0.002
M22.9 Disorder of patella, unspecified	0.000	0.997	0.003
E34.5 Androgen resistance syndrome	0.001	0.997	0.002
E34.4 Constitutional tall stature	0.001	0.997	0.002
E34.2 Ectopic hormone secretion, not elsewhere classified	0.001	0.997	0.002
E34.1 Other hypersecretion of intestinal hormones	0.001	0.997	0.002
L52 Erythema nodosum	0.000	0.997	0.003
E46 Unspecified protein-energy malnutrition	0.000	0.997	0.002
F25 Schizoaffective disorders	0.000	0.997	0.003
M00.94 Pyogenic arthritis, unspecified (Hand)	0.002	0.997	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.997	0.002
H01.1 Non-infectious dermatoses of eyelid	0.002	0.997	0.000
M20.2 Hallux rigidus	0.000	0.997	0.002
H01 Other inflammation of eyelid	0.002	0.997	0.000
E34.3 Short stature, not elsewhere classified	0.001	0.998	0.002
E13.9 Without complications	0.000	0.998	0.002
X50.4 Street and highway	0.002	0.998	0.000
X51.9 Unspecified place	0.002	0.998	0.000
E14 Unspecified diabetes mellitus	0.000	0.998	0.002
S01.8 Open wound of other parts of head	0.000	0.998	0.002
L50.6 Contact urticaria	0.000	0.998	0.002
L50.5 Cholinergic urticaria	0.000	0.998	0.002
L50.4 Vibratory urticaria	0.000	0.998	0.002
L50.3 Dermatographic urticaria	0.000	0.998	0.002
L50.2 Urticaria due to cold and heat	0.000	0.998	0.002
X20-X29 Contact with venomous animals and plants	0.000	0.998	0.002
H01.8 Other specified inflammation of eyelid	0.002	0.998	0.000
T15.0 Foreign body in cornea	0.002	0.998	0.000
E14.1 With ketoacidosis	0.000	0.998	0.002
G57.5 Tarsal tunnel syndrome	0.002	0.998	0.000
M00 Pyogenic arthritis	0.002	0.998	0.000
S01.2 Open wound of nose	0.000	0.998	0.002
I45.9 Conduction disorder, unspecified	0.000	0.998	0.002
C83.0 Small cell (diffuse)	0.002	0.998	0.000
E14.8 With unspecified complications	0.000	0.998	0.002
E34.8 Other specified endocrine disorders	0.001	0.998	0.002
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
G57.4 Lesion of medial popliteal nerve	0.002	0.998	0.000
G57.3 Lesion of lateral popliteal nerve	0.002	0.998	0.000
G57.2 Lesion of femoral nerve	0.002	0.998	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.002	0.998	0.000
G57.8 Other mononeuropathies of lower limb	0.002	0.998	0.000
G57.0 Lesion of sciatic nerve	0.002	0.998	0.000
T15 Foreign body on external eye	0.002	0.998	0.000
F25.2 Schizoaffective disorder, mixed type	0.000	0.998	0.002
Z04.3 Examination and observation following other accident	0.002	0.998	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.001	0.998	0.002
S00.3 Superficial injury of nose	0.002	0.998	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
X50 Overexertion and strenuous or repetitive movements	0.002	0.998	0.000
X47.0 Home	0.002	0.998	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.998	0.002
T78.3 Angioneurotic oedema	0.002	0.998	0.000
E67 Other hyperalimentation	0.000	0.998	0.002
E68 Sequelae of hyperalimentation	0.000	0.998	0.002
M77.47 Metatarsalgia-Ankle/Foot	0.002	0.998	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.002	0.998	0.000
Z03.6 Observation for suspected toxic effect from ingested substance	0.002	0.998	0.000
F25.8 Other schizoaffective disorders	0.000	0.998	0.002
E14.2 Withrenal complications	0.000	0.998	0.002
X51 Travel and motion	0.002	0.998	0.000
C41.0 Bones of skull and face	0.002	0.998	0.000
T16 Foreign body in ear	0.002	0.998	0.000
E14.6 With other specified complications	0.000	0.998	0.002
E14.7 With multiple complications	0.000	0.998	0.002
E14.0 With coma	0.000	0.998	0.002
E34.9 Endocrine disorder, unspecified	0.001	0.998	0.001
E29.1 Testicular hypofunction	0.000	0.998	0.002
X50.2 School, other institution and public administrative area	0.002	0.998	0.000
X47 Accidental poisoning by and exposure to other gases and vapours	0.002	0.998	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.998	0.002
X41.2 School, other institution and public administrative area	0.002	0.998	0.000
X50.6 Industrial and construction area	0.002	0.998	0.000
X29 Contact with unspecified venomous animal or plant	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations