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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844795
log Bayes Factor = 67.4036
Chromosome 6   position 30,073,847  (GRCh37) Explore rs2844795 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
0.999 0.001 0.000
E83 Disorders of mineral metabolism
0.999 0.001 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.998 0.002 0.000
E10.1 With ketoacidosis
0.996 0.004 0.000
E14 Unspecified diabetes mellitus
0.995 0.005 0.000
E14.3 With ophthalmic complications
0.994 0.006 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.980 0.020 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.977 0.023 0.000
E20-E35 Disorders of other endocrine glands
0.973 0.027 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.971 0.029 0.000
E89.0 Postprocedural hypothyroidism
0.964 0.036 0.000
E27 Other disorders of adrenal gland
0.962 0.038 0.000
E27.1 Primary adrenocortical insufficiency
0.962 0.038 0.000
E10.4 With neurological complications
0.954 0.046 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.953 0.047 0.000
E10.3 With ophthalmic complications
0.946 0.054 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.942 0.058 0.000
M06 Other rheumatoid arthritis
0.926 0.074 0.000
E16 Other disorders of pancreatic internal secretion
0.920 0.080 0.000
E85 Amyloidosis
0.909 0.091 0.000
E14.6 With other specified complications
0.904 0.096 0.000
E73 Lactose intolerance
0.904 0.096 0.000
E24 Cushing's syndrome
0.903 0.097 0.000
E10.5 With peripheral circulatory complications
0.902 0.098 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.899 0.101 0.000
E16.2 Hypoglycaemia, unspecified
0.897 0.103 0.000
K90 Intestinal malabsorption
0.864 0.136 0.000
K75.4 Autoimmune hepatitis
0.861 0.139 0.000
K75 Other inflammatory liver diseases
0.859 0.141 0.000
K70-K77 Diseases of liver
0.855 0.145 0.000
K70 Alcoholic liver disease
0.853 0.147 0.000
M05-M14 Inflammatory polyarthropathies
0.849 0.151 0.000
E80.4 Gilbert's syndrome
0.842 0.158 0.000
E73.9 Lactose intolerance, unspecified
0.836 0.164 0.000
M05 Seropositive rheumatoid arthritis
0.835 0.165 0.000
E13 Other specified diabetes mellitus
0.832 0.168 0.000
E10.6 With other specified complications
0.831 0.169 0.000
E10.0 With coma
0.830 0.170 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.825 0.175 0.000
K70.0 Alcoholic fatty liver
0.816 0.184 0.000
E85.4 Organ-limited amyloidosis
0.806 0.194 0.000
E89.2 Postprocedural hypoparathyroidism
0.803 0.197 0.000
K73 Chronic hepatitis, not elsewhere classified
0.802 0.198 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.799 0.201 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.797 0.203 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.796 0.204 0.000
E10.2 With renal complications
0.795 0.205 0.000
E31 Polyglandular dysfunction
0.795 0.205 0.000
M06.4 Inflammatory polyarthropathy
0.789 0.211 0.000
E34 Other endocrine disorders
0.788 0.212 0.000
E04 Other non-toxic goitre
0.783 0.217 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.783 0.217 0.000
K51 Ulcerative colitis
0.783 0.217 0.000
K51.9 Ulcerative colitis, unspecified
0.782 0.218 0.000
E03.8 Other specified hypothyroidism
0.782 0.218 0.000
K75.8 Other specified inflammatory liver diseases
0.770 0.230 0.000
E10.7 With multiple complications
0.767 0.233 0.000
E80.1 Porphyria cutanea tarda
0.767 0.233 0.000
E14.8 With unspecified complications
0.764 0.236 0.000
M14 Arthropathies in other diseases classified elsewhere
0.761 0.239 0.000
E20 Hypoparathyroidism
0.759 0.241 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.758 0.242 0.000
E10.8 With unspecified complications
0.757 0.243 0.000
E84 Cystic fibrosis
0.754 0.246 0.000
E50-E64 Other nutritional deficiencies
0.747 0.253 0.000
E80.2 Other porphyria
0.744 0.256 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.743 0.257 0.000
E06 Thyroiditis
0.742 0.258 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.742 0.258 0.000
E24.9 Cushing's syndrome, unspecified
0.739 0.261 0.000
E24.0 Pituitary-dependent Cushing's disease
0.737 0.263 0.000
K70.9 Alcoholic liver disease, unspecified
0.736 0.264 0.000
E25 Adrenogenital disorders
0.735 0.265 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.735 0.265 0.000
E07 Other disorders of thyroid
0.735 0.265 0.000
M06.8 Other specified rheumatoid arthritis
0.735 0.265 0.000
E24.2 Drug-induced Cushing's syndrome
0.734 0.266 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.731 0.268 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.724 0.276 0.000
K51.8 Other ulcerative colitis
0.724 0.276 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.724 0.276 0.000
E24.8 Other Cushing's syndrome
0.720 0.280 0.000
E85.3 Secondary systemic amyloidosis
0.719 0.280 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
E83.8 Other disorders of mineral metabolism
0.716 0.284 0.000
E83.2 Disorders of zinc metabolism
0.716 0.284 0.000
E83.0 Disorders of copper metabolism
0.716 0.284 0.000
M12 Other specific arthropathies
0.715 0.285 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.714 0.286 0.000
E14.7 With multiple complications
0.714 0.286 0.000
E14.0 With coma
0.714 0.286 0.000
E85.9 Amyloidosis, unspecified
0.713 0.287 0.000
K51.4 Pseudopolyposis of colon
0.709 0.291 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.707 0.293 0.000
K70.3 Alcoholic cirrhosis of liver
0.707 0.293 0.000
E74 Other disorders of carbohydrate metabolism
0.704 0.296 0.000
K73.9 Chronic hepatitis, unspecified
0.703 0.297 0.000
K90-K93 Other diseases of the digestive system
0.701 0.299 0.000
M06.1 Adult-onset Still's disease
0.701 0.299 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.700 0.300 0.000
E89.5 Postprocedural testicular hypofunction
0.700 0.300 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.698 0.302 0.000
E32 Diseases of thymus
0.698 0.302 0.000
E30 Disorders of puberty, not elsewhere classified
0.698 0.302 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.697 0.303 0.000
E89.1 Postprocedural hypoinsulinaemia
0.696 0.304 0.000
K50-K52 Noninfective enteritis and colitis
0.695 0.305 0.000
Chapter XI Diseases of the digestive system
0.691 0.309 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.690 0.310 0.000
E27.5 Adrenomedullary hyperfunction
0.690 0.310 0.000
E27.0 Other adrenocortical overactivity
0.690 0.310 0.000
K90.9 Intestinal malabsorption, unspecified
0.687 0.313 0.000
E15 Nondiabetic hypoglycaemic coma
0.683 0.317 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.682 0.317 0.000
E28 Ovarian dysfunction
0.682 0.318 0.000
K70.4 Alcoholic hepatic failure
0.681 0.319 0.000
E34.9 Endocrine disorder, unspecified
0.679 0.321 0.000
E65-E68 Obesity and other hyperalimentation
0.678 0.322 0.000
E11 Non-insulin-dependent diabetes mellitus
0.677 0.323 0.000
E80.5 Crigler-Najjar syndrome
0.675 0.324 0.000
E80.3 Defects of catalase and peroxydase
0.675 0.324 0.000
E80.0 Hereditary erythropoietic porphyria
0.675 0.324 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.675 0.324 0.000
E14.1 With ketoacidosis
0.675 0.325 0.000
E72 Other disorders of amino-acid metabolism
0.674 0.325 0.000
E14.2 Withrenal complications
0.674 0.326 0.000
E79 Disorders of purine and pyrimidine metabolism
0.672 0.328 0.000
E29 Testicular dysfunction
0.669 0.331 0.000
E13.9 Without complications
0.668 0.332 0.000
E80.6 Other disorders of bilirubin metabolism
0.667 0.333 0.000
E31.0 Autoimmune polyglandular failure
0.667 0.333 0.000
M10 Gout
0.665 0.335 0.000
K75.0 Abscess of liver
0.665 0.335 0.000
M06.2 Rheumatoid bursitis
0.664 0.336 0.000
E13.3 With ophthalmic complications
0.660 0.340 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.659 0.341 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.659 0.341 0.000
E16.4 Abnormal secretion of gastrin
0.659 0.341 0.000
E16.3 Increased secretion of glucagon
0.659 0.341 0.000
E04.9 Non-toxic goitre, unspecified
0.659 0.341 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.656 0.344 0.000
K51.5 Mucosal proctocolitis
0.655 0.345 0.000
M06.3 Rheumatoid nodule
0.655 0.345 0.000
E70 Disorders of aromatic amino-acid metabolism
0.654 0.346 0.000
E06.3 Autoimmune thyroiditis
0.652 0.348 0.000
E03.1 Congenital hypothyroidism without goitre
0.652 0.348 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.652 0.348 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.652 0.348 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.652 0.348 0.000
E11.5 With peripheral circulatory complications
0.650 0.350 0.000
E14.5 With peripheral circulatory complications
0.648 0.351 0.000
E73.8 Other lactose intolerance
0.648 0.352 0.000
E73.1 Secondary lactase deficiency
0.648 0.352 0.000
E73.0 Congenital lactase deficiency
0.648 0.352 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.648 0.352 0.000
E53 Deficiency of other B group vitamins
0.647 0.353 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.647 0.353 0.000
E24.3 Ectopic ACTH syndrome
0.647 0.353 0.000
E24.1 Nelson's syndrome
0.647 0.353 0.000
K77 Liver disorders in diseases classified elsewhere
0.647 0.353 0.000
E40-E46 Malnutrition
0.646 0.354 0.000
E89.4 Postprocedural ovarian failure
0.639 0.360 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.639 0.361 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.639 0.361 0.000
K90.8 Other intestinal malabsorption
0.634 0.366 0.000
E11.3 With ophthalmic complications
0.633 0.367 0.000
M05.8 Other seropositive rheumatoid arthritis
0.631 0.369 0.000
E04.0 Non-toxic diffuse goitre
0.628 0.372 0.000
M14.6 Neuropathic arthropathy
0.625 0.375 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.621 0.379 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.620 0.379 0.000
E85.8 Other amyloidosis
0.620 0.380 0.000
E04.2 Non-toxic multinodular goitre
0.620 0.380 0.000
K90.3 Pancreatic steatorrhoea
0.619 0.381 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.619 0.381 0.000
K90.1 Tropical sprue
0.619 0.381 0.000
K75.2 Nonspecific reactive hepatitis
0.616 0.384 0.000
K75.1 Phlebitis of portal vein
0.616 0.384 0.000
M10.0 Idiopathic gout
0.615 0.385 0.000
E27.2 Addisonian crisis
0.613 0.387 0.000
E89.3 Postprocedural hypopituitarism
0.613 0.387 0.000
E14.4 With neurological complications
0.611 0.389 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.609 0.391 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.609 0.391 0.000
M08 Juvenile arthritis
0.607 0.393 0.000
E20.9 Hypoparathyroidism, unspecified
0.606 0.394 0.000
E28.3 Primary ovarian failure
0.605 0.395 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.599 0.401 0.000
M05.0 Felty's syndrome
0.599 0.401 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.597 0.403 0.000
E13.8 With unspecified complications
0.597 0.403 0.000
E13.7 With multiple complications
0.597 0.403 0.000
E13.6 With other specified complications
0.597 0.403 0.000
E13.5 With peripheral circulatory complications
0.597 0.403 0.000
E13.4 With neurological complications
0.597 0.403 0.000
E13.2 With renal complications
0.597 0.403 0.000
E13.1 With ketoacidosis
0.597 0.403 0.000
E13.0 With coma
0.597 0.403 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.594 0.406 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.591 0.409 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.591 0.409 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.586 0.414 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.584 0.416 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.584 0.416 0.000
M14.2 Diabetic arthropathy
0.583 0.417 0.000
M05.1 Rheumatoid lung disease
0.582 0.418 0.000
M05.2 Rheumatoid vasculitis
0.581 0.418 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.580 0.420 0.000
E51 Thiamine deficiency
0.580 0.420 0.000
M12.2 Villonodular synovitis (pigmented)
0.580 0.420 0.000
E84.9 Cystic fibrosis, unspecified
0.577 0.423 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.575 0.425 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.575 0.425 0.000
E34.0 Carcinoid syndrome
0.575 0.425 0.000
E31.9 Polyglandular dysfunction, unspecified
0.570 0.430 0.000
E31.8 Other polyglandular dysfunction
0.570 0.430 0.000
E31.1 Polyglandular hyperfunction
0.570 0.430 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.567 0.433 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.566 0.434 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.566 0.434 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.566 0.434 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.566 0.434 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.566 0.434 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.566 0.434 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.566 0.434 0.000
K71 Toxic liver disease
0.566 0.434 0.000
E63 Other nutritional deficiencies
0.565 0.434 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.565 0.435 0.000
E34.5 Androgen resistance syndrome
0.565 0.435 0.000
E34.4 Constitutional tall stature
0.565 0.435 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.565 0.435 0.000
E34.1 Other hypersecretion of intestinal hormones
0.565 0.435 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.563 0.436 0.000
E83.4 Disorders of magnesium metabolism
0.562 0.438 0.000
E04.8 Other specified non-toxic goitre
0.561 0.438 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.555 0.445 0.000
E07.9 Disorder of thyroid, unspecified
0.555 0.445 0.000
E54 Ascorbic acid deficiency
0.553 0.447 0.000
E53.8 Deficiency of other specified B group vitamins
0.552 0.448 0.000
E22 Hyperfunction of pituitary gland
0.552 0.448 0.000
M12.3 Palindromic rheumatism
0.552 0.448 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.549 0.450 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.546 0.454 0.000
M14.4 Arthropathy in amyloidosis
0.546 0.454 0.000
M14.3 Lipoid dermatoarthritis
0.546 0.454 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.546 0.454 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.546 0.454 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.545 0.455 0.000
E20.8 Other hypoparathyroidism
0.544 0.455 0.000
E20.1 Pseudohypoparathyroidism
0.544 0.455 0.000
E20.0 Idiopathic hypoparathyroidism
0.544 0.455 0.000
K74 Fibrosis and cirrhosis of liver
0.544 0.456 0.000
E84.8 Cystic fibrosis with other manifestations
0.540 0.460 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.540 0.460 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.540 0.460 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.540 0.460 0.000
E34.3 Short stature, not elsewhere classified
0.538 0.462 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.538 0.462 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.536 0.464 0.000
E50 Vitamin A deficiency
0.536 0.464 0.000
E60 Dietary zinc deficiency
0.536 0.464 0.000
E59 Dietary selenium deficiency
0.536 0.464 0.000
E52 Niacin deficiency [pellagra]
0.536 0.464 0.000
E56 Other vitamin deficiencies
0.533 0.467 0.000
E34.8 Other specified endocrine disorders
0.533 0.467 0.000
E06.4 Drug-induced thyroiditis
0.532 0.468 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.532 0.468 0.000
E06.1 Subacute thyroiditis
0.532 0.468 0.000
E06.0 Acute thyroiditis
0.532 0.468 0.000
E58 Dietary calcium deficiency
0.532 0.468 0.000
M11 Other crystal arthropathies
0.531 0.468 0.000
K75.9 Inflammatory liver disease, unspecified
0.530 0.470 0.000
E83.3 Disorders of phosphorus metabolism
0.528 0.472 0.000
E25.9 Adrenogenital disorder, unspecified
0.527 0.473 0.000
E25.8 Other adrenogenital disorders
0.527 0.473 0.000
E07.1 Dyshormogenetic goitre
0.527 0.473 0.000
E07.0 Hypersecretion of calcitonin
0.527 0.473 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.527 0.473 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.527 0.473 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.527 0.473 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.527 0.473 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.527 0.473 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.527 0.473 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.527 0.473 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.527 0.473 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.526 0.474 0.000
M12.5 Traumatic arthropathy
0.525 0.475 0.000
E07.8 Other specified disorders of thyroid
0.517 0.483 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E71.3 Disorders of fatty-acid metabolism
0.514 0.486 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.514 0.486 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.514 0.486 0.000
E71.0 Maple-syrup-urine disease
0.514 0.486 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.514 0.486 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.514 0.486 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.514 0.486 0.000
E76.2 Other mucopolysaccharidoses
0.514 0.486 0.000
E76.1 Mucopolysaccharidosis, type II
0.514 0.486 0.000
E76.0 Mucopolysaccharidosis, type I
0.514 0.486 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.514 0.486 0.000
E77.8 Other disorders of glycoprotein metabolism
0.514 0.486 0.000
E77.1 Defects in glycoprotein degradation
0.514 0.486 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.514 0.486 0.000
M12.4 Intermittent hydrarthrosis
0.513 0.487 0.000
M12.1 Kaschin-Beck disease
0.513 0.487 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.513 0.487 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.511 0.489 0.000
E53.9 Vitamin B deficiency, unspecified
0.510 0.490 0.000
E16.1 Other hypoglycaemia
0.508 0.491 0.000
E65 Localised adiposity
0.505 0.495 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.505 0.495 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.505 0.495 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.505 0.495 0.000
E74.2 Disorders of galactose metabolism
0.505 0.495 0.000
E74.1 Disorders of fructose metabolism
0.505 0.495 0.000
E06.5 Other chronic thyroiditis
0.504 0.495 0.000
E11.7 With multiple complications
0.503 0.497 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.503 0.497 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.503 0.497 0.000
M06.18 Adult-onset Still's disease (Other)
0.503 0.497 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.503 0.497 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.503 0.497 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.503 0.497 0.000
M06.14 Adult-onset Still's disease (Hand)
0.503 0.497 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.503 0.497 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.503 0.497 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.503 0.497 0.000
E74.0 Glycogen storage disease
0.501 0.499 0.000
E30.9 Disorder of puberty, unspecified
0.500 0.500 0.000
E30.8 Other disorders of puberty
0.500 0.500 0.000
E30.1 Precocious puberty
0.500 0.500 0.000
E30.0 Delayed puberty
0.500 0.500 0.000
E32.9 Disease of thymus, unspecified
0.500 0.500 0.000
E32.8 Other diseases of thymus
0.500 0.500 0.000
E32.1 Abscess of thymus
0.500 0.500 0.000
E32.0 Persistent hyperplasia of thymus
0.500 0.500 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.500 0.500 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.500 0.500 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.500 0.500 0.000
K77.8 Liver disorders in other diseases classified elsewhere
0.498 0.502 0.000
E29.9 Testicular dysfunction, unspecified
0.498 0.502 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.497 0.503 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.497 0.503 0.000
E11.8 With unspecified complications
0.493 0.507 0.000
E26 Hyperaldosteronism
0.491 0.509 0.000
E28.9 Ovarian dysfunction, unspecified
0.489 0.511 0.000
E28.8 Other ovarian dysfunction
0.489 0.511 0.000
E28.1 Androgen excess
0.489 0.511 0.000
E28.0 Oestrogen excess
0.489 0.511 0.000
E67 Other hyperalimentation
0.486 0.514 0.000
E68 Sequelae of hyperalimentation
0.486 0.514 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.485 0.515 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.484 0.516 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.484 0.516 0.000
E72.5 Disorders of glycine metabolism
0.484 0.516 0.000
E72.4 Disorders of ornithine metabolism
0.484 0.516 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.484 0.516 0.000
E72.2 Disorders of urea cycle metabolism
0.484 0.516 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.484 0.516 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.483 0.517 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.482 0.518 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.482 0.518 0.000
E79.1 Lesch-Nyhan syndrome
0.482 0.518 0.000
L40.9 Psoriasis, unspecified
0.000 0.519 0.481
E29.8 Other testicular dysfunction
0.480 0.520 0.000
E29.0 Testicular hyperfunction
0.480 0.520 0.000
E11.1 With ketoacidosis
0.478 0.522 0.000
M10.4 Other secondary gout
0.477 0.523 0.000
M10.3 Gout due to impairment of renal function
0.477 0.523 0.000
M10.2 Drug-induced gout
0.477 0.523 0.000
M10.1 Lead-induced gout
0.477 0.523 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.476 0.524 0.000
M06.28 Rheumatoid bursitis (Other)
0.476 0.524 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.476 0.524 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.476 0.524 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.476 0.524 0.000
M06.24 Rheumatoid bursitis (Hand)
0.476 0.524 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.476 0.524 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.476 0.524 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.476 0.524 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.476 0.524 0.000
M06.34 Rheumatoid nodule (Hand)
0.476 0.524 0.000
M12.24 Villonodular synovitis (pigmented) (Hand)
0.473 0.527 0.000
M10.04 Idiopathic gout (Hand)
0.473 0.527 0.000
K70.1 Alcoholic hepatitis
0.472 0.528 0.000
M10.06 Idiopathic gout (Lower leg)
0.471 0.529 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.470 0.530 0.000
M06.38 Rheumatoid nodule (Other)
0.470 0.530 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.470 0.530 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.470 0.530 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.470 0.530 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.469 0.531 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.469 0.531 0.000
E70.2 Disorders of tyrosine metabolism
0.469 0.531 0.000
E70.1 Other hyperphenylalaninaemias
0.469 0.531 0.000
E70.0 Classical phenylketonuria
0.469 0.531 0.000
E05.8 Other thyrotoxicosis
0.468 0.532 0.001
M06.33 Rheumatoid nodule (Forearm)
0.468 0.532 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.465 0.535 0.000
E53.1 Pyridoxine deficiency
0.464 0.536 0.000
E53.0 Riboflavin deficiency
0.464 0.536 0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.464 0.536 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.463 0.537 0.000
E45 Retarded development following protein-energy malnutrition
0.463 0.537 0.000
E43 Unspecified severe protein-energy malnutrition
0.463 0.537 0.000
E42 Marasmic kwashiorkor
0.463 0.537 0.000
E41 Nutritional marasmus
0.463 0.537 0.000
E40 Kwashiorkor
0.463 0.537 0.000
E51.2 Wernicke's encephalopathy
0.460 0.540 0.000
K72 Hepatic failure, not elsewhere classified
0.456 0.544 0.000
M10.02 Idiopathic gout (Upper arm)
0.456 0.544 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.452 0.547 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.452 0.547 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.452 0.547 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.452 0.547 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.452 0.547 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.452 0.547 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.452 0.547 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.452 0.547 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.452 0.547 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.447 0.552 0.000
E72.0 Disorders of amino-acid transport
0.441 0.558 0.000
M10.08 Idiopathic gout (Other)
0.441 0.559 0.000
M10.05 Idiopathic gout (Pelvic region and thigh)
0.441 0.559 0.000
M10.03 Idiopathic gout (Forearm)
0.441 0.559 0.000
M10.01 Idiopathic gout (Shoulder region)
0.441 0.559 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.438 0.562 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.438 0.562 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.437 0.563 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.437 0.563 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.437 0.563 0.000
M09.0 Juvenile arthritis in psoriasis
0.437 0.563 0.000
M08.9 Juvenile arthritis, unspecified
0.435 0.564 0.000
M08.8 Other juvenile arthritis
0.435 0.564 0.000
M08.4 Pauciarticular juvenile arthritis
0.435 0.564 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.435 0.564 0.000
M08.2 Juvenile arthritis with systemic onset
0.435 0.564 0.000
M08.1 Juvenile ankylosing spondylitis
0.435 0.564 0.000
E63.9 Nutritional deficiency, unspecified
0.435 0.565 0.000
M08.0 Juvenile rheumatoid arthritis
0.434 0.566 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.433 0.567 0.000
K71.0 Toxic liver disease with cholestasis
0.432 0.567 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.432 0.568 0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)
0.430 0.570 0.000
M05.09 Felty's syndrome (Site unspecified)
0.429 0.571 0.000
M05.08 Felty's syndrome (Other)
0.429 0.571 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.429 0.571 0.000
M05.06 Felty's syndrome (Lower leg)
0.429 0.571 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.429 0.571 0.000
M05.04 Felty's syndrome (Hand)
0.429 0.571 0.000
M05.03 Felty's syndrome (Forearm)
0.429 0.571 0.000
M05.02 Felty's syndrome (Upper arm)
0.429 0.571 0.000
M05.01 Felty's syndrome (Shoulder region)
0.429 0.571 0.000
M05.00 Felty's syndrome (Multiple sites)
0.429 0.571 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.429 0.571 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.429 0.571 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.429 0.571 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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