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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2847278
log Bayes Factor = 11.9236
Chromosome 18   position 12,778,715  (GRCh37) Explore rs2847278 on Ensembl!
Variant rs2847278 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E20-E35 Disorders of other endocrine glands
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.006 0.994
E10.3 With ophthalmic complications
0.000 0.015 0.985
E11.3 With ophthalmic complications
0.000 0.016 0.984
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.022 0.978
E10.1 With ketoacidosis
0.000 0.051 0.949
E27 Other disorders of adrenal gland
0.000 0.055 0.945
E21.0 Primary hyperparathyroidism
0.000 0.056 0.944
E11.1 With ketoacidosis
0.000 0.093 0.907
K50 Crohn's disease [regional enteritis]
0.000 0.093 0.907
K50.9 Crohn's disease, unspecified
0.000 0.097 0.903
K50.0 Crohn's disease of small intestine
0.000 0.114 0.886
E24 Cushing's syndrome
0.000 0.115 0.885
D50.9 Iron deficiency anaemia, unspecified
0.000 0.132 0.868
K50.1 Crohn's disease of large intestine
0.000 0.134 0.866
E27.9 Disorder of adrenal gland, unspecified
0.000 0.136 0.864
D50 Iron deficiency anaemia
0.000 0.138 0.862
E23 Hypofunction and other disorders of pituitary gland
0.000 0.138 0.862
E10.6 With other specified complications
0.000 0.143 0.857
E10.4 With neurological complications
0.000 0.149 0.851
E29 Testicular dysfunction
0.000 0.159 0.841
E21.3 Hyperparathyroidism, unspecified
0.000 0.162 0.838
D50.8 Other iron deficiency anaemias
0.000 0.170 0.830
E03.1 Congenital hypothyroidism without goitre
0.000 0.171 0.829
D50-D53 Nutritional anaemias
0.000 0.171 0.829
D51 Vitamin B12 deficiency anaemia
0.000 0.174 0.826
E11.6 With other specified complications
0.000 0.189 0.811
E34 Other endocrine disorders
0.000 0.191 0.809
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.192 0.808
E27.8 Other specified disorders of adrenal gland
0.000 0.202 0.798
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.203 0.797
K50.8 Other Crohn's disease
0.000 0.203 0.797
K50-K52 Noninfective enteritis and colitis
0.000 0.205 0.795
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.206 0.794
E21.4 Other specified disorders of parathyroid gland
0.000 0.209 0.791
E11.2 With renal complications
0.000 0.211 0.789
E22 Hyperfunction of pituitary gland
0.000 0.211 0.789
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.217 0.783
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.220 0.780
K51 Ulcerative colitis
0.000 0.220 0.780
E14 Unspecified diabetes mellitus
0.000 0.223 0.777
E13 Other specified diabetes mellitus
0.000 0.233 0.767
E10.8 With unspecified complications
0.000 0.243 0.756
E32 Diseases of thymus
0.000 0.245 0.755
E11.5 With peripheral circulatory complications
0.000 0.251 0.749
E24.9 Cushing's syndrome, unspecified
0.000 0.253 0.747
K51.4 Pseudopolyposis of colon
0.000 0.257 0.743
E23.6 Other disorders of pituitary gland
0.000 0.266 0.734
K51.9 Ulcerative colitis, unspecified
0.000 0.268 0.732
E25 Adrenogenital disorders
0.000 0.270 0.730
E11.7 With multiple complications
0.000 0.273 0.727
E31 Polyglandular dysfunction
0.000 0.277 0.723
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.716
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.293 0.707
E40-E46 Malnutrition
0.000 0.294 0.706
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.295 0.705
E29.1 Testicular hypofunction
0.000 0.303 0.697
E50-E64 Other nutritional deficiencies
0.000 0.305 0.695
E24.0 Pituitary-dependent Cushing's disease
0.000 0.306 0.693
E14.9 Without complications
0.000 0.307 0.693
E10.7 With multiple complications
0.000 0.314 0.686
E23.7 Disorder of pituitary gland, unspecified
0.000 0.317 0.683
E27.5 Adrenomedullary hyperfunction
0.000 0.322 0.678
E27.0 Other adrenocortical overactivity
0.000 0.322 0.678
E11.8 With unspecified complications
0.000 0.324 0.676
E24.2 Drug-induced Cushing's syndrome
0.000 0.325 0.674
E10.0 With coma
0.000 0.326 0.673
E11.0 With coma
0.000 0.331 0.669
E26 Hyperaldosteronism
0.000 0.337 0.663
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.338 0.662
E34.8 Other specified endocrine disorders
0.000 0.341 0.659
E10.5 With peripheral circulatory complications
0.000 0.343 0.656
E20 Hypoparathyroidism
0.000 0.344 0.656
E24.8 Other Cushing's syndrome
0.000 0.346 0.654
E29.9 Testicular dysfunction, unspecified
0.000 0.347 0.653
E07 Other disorders of thyroid
0.000 0.348 0.652
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.348 0.651
E14.1 With ketoacidosis
0.000 0.356 0.644
E23.0 Hypopituitarism
0.000 0.357 0.643
E34.0 Carcinoid syndrome
0.000 0.360 0.640
E22.1 Hyperprolactinaemia
0.000 0.364 0.636
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.365 0.635
E24.3 Ectopic ACTH syndrome
0.000 0.365 0.635
E24.1 Nelson's syndrome
0.000 0.365 0.635
E27.1 Primary adrenocortical insufficiency
0.000 0.366 0.634
E14.4 With neurological complications
0.000 0.372 0.628
E53 Deficiency of other B group vitamins
0.000 0.372 0.628
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.375 0.625
E06 Thyroiditis
0.000 0.380 0.620
E23.1 Drug-induced hypopituitarism
0.000 0.382 0.618
E03.8 Other specified hypothyroidism
0.000 0.385 0.615
D50.1 Sideropenic dysphagia
0.000 0.390 0.610
E29.8 Other testicular dysfunction
0.000 0.397 0.603
E29.0 Testicular hyperfunction
0.000 0.397 0.603
E21.2 Other hyperparathyroidism
0.000 0.399 0.601
K51.5 Mucosal proctocolitis
0.000 0.402 0.598
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.402 0.597
E05.9 Thyrotoxicosis, unspecified
0.000 0.403 0.597
D51.2 Transcobalamin II deficiency
0.000 0.408 0.592
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.408 0.592
E13.9 Without complications
0.000 0.412 0.588
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.412 0.588
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.414 0.586
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.419 0.581
E27.2 Addisonian crisis
0.000 0.419 0.580
E34.5 Androgen resistance syndrome
0.000 0.420 0.580
E34.4 Constitutional tall stature
0.000 0.420 0.580
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.420 0.580
E34.1 Other hypersecretion of intestinal hormones
0.000 0.420 0.580
E53.8 Deficiency of other specified B group vitamins
0.000 0.420 0.580
E32.8 Other diseases of thymus
0.000 0.420 0.580
E34.3 Short stature, not elsewhere classified
0.000 0.426 0.574
E28 Ovarian dysfunction
0.000 0.427 0.573
E11.4 With neurological complications
0.000 0.429 0.571
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.429 0.571
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.431 0.569
E22.8 Other hyperfunction of pituitary gland
0.000 0.434 0.566
D52 Folate deficiency anaemia
0.000 0.435 0.565
E13.3 With ophthalmic complications
0.000 0.436 0.564
E14.7 With multiple complications
0.000 0.443 0.557
E10.2 With renal complications
0.000 0.446 0.554
E05.8 Other thyrotoxicosis
0.000 0.446 0.554
E13.8 With unspecified complications
0.000 0.450 0.550
E13.7 With multiple complications
0.000 0.450 0.550
E13.6 With other specified complications
0.000 0.450 0.550
E13.5 With peripheral circulatory complications
0.000 0.450 0.550
E13.4 With neurological complications
0.000 0.450 0.550
E13.2 With renal complications
0.000 0.450 0.550
E13.1 With ketoacidosis
0.000 0.450 0.550
E13.0 With coma
0.000 0.450 0.550
E14.0 With coma
0.000 0.457 0.543
E32.9 Disease of thymus, unspecified
0.000 0.458 0.541
E32.1 Abscess of thymus
0.000 0.458 0.541
E32.0 Persistent hyperplasia of thymus
0.000 0.458 0.541
E34.9 Endocrine disorder, unspecified
0.000 0.462 0.537
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.463 0.537
E14.8 With unspecified complications
0.000 0.465 0.535
K51.8 Other ulcerative colitis
0.000 0.465 0.535
E14.6 With other specified complications
0.000 0.465 0.535
D53 Other nutritional anaemias
0.000 0.469 0.531
K90.0 Coeliac disease
0.000 0.470 0.530
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.472 0.528
E31.0 Autoimmune polyglandular failure
0.000 0.476 0.524
E25.9 Adrenogenital disorder, unspecified
0.000 0.476 0.523
E25.8 Other adrenogenital disorders
0.000 0.476 0.523
E11.9 Without complications
0.000 0.480 0.520
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.481 0.519
E31.9 Polyglandular dysfunction, unspecified
0.000 0.482 0.518
E31.8 Other polyglandular dysfunction
0.000 0.482 0.518
E31.1 Polyglandular hyperfunction
0.000 0.482 0.518
E16 Other disorders of pancreatic internal secretion
0.000 0.485 0.515
E15 Nondiabetic hypoglycaemic coma
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.514
E30.8 Other disorders of puberty
0.000 0.486 0.514
E30.1 Precocious puberty
0.000 0.486 0.514
E30.0 Delayed puberty
0.000 0.486 0.514
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.514
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.514
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E23.2 Diabetes insipidus
0.000 0.488 0.512
E58 Dietary calcium deficiency
0.000 0.490 0.510
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.494 0.506
E45 Retarded development following protein-energy malnutrition
0.000 0.494 0.506
E43 Unspecified severe protein-energy malnutrition
0.000 0.494 0.506
E42 Marasmic kwashiorkor
0.000 0.494 0.506
E41 Nutritional marasmus
0.000 0.494 0.506
E40 Kwashiorkor
0.000 0.494 0.506
E05.5 Thyroid crisis or storm
0.000 0.494 0.506
E05.4 Thyrotoxicosis factitia
0.000 0.494 0.506
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.494 0.506
E14.5 With peripheral circulatory complications
0.000 0.501 0.499
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.502 0.498
E50 Vitamin A deficiency
0.000 0.502 0.498
E60 Dietary zinc deficiency
0.000 0.502 0.498
E59 Dietary selenium deficiency
0.000 0.502 0.498
E52 Niacin deficiency [pellagra]
0.000 0.502 0.498
E46 Unspecified protein-energy malnutrition
0.000 0.505 0.495
E14.2 Withrenal complications
0.000 0.509 0.491
E56 Other vitamin deficiencies
0.000 0.512 0.488
E06.3 Autoimmune thyroiditis
0.000 0.520 0.480
K51.2 Ulcerative (chronic) proctitis
0.000 0.521 0.479
E63 Other nutritional deficiencies
0.000 0.524 0.476
E26.8 Other hyperaldosteronism
0.000 0.524 0.476
E26.1 Secondary hyperaldosteronism
0.000 0.524 0.476
E54 Ascorbic acid deficiency
0.000 0.528 0.472
E26.9 Hyperaldosteronism, unspecified
0.000 0.529 0.471
E20.0 Idiopathic hypoparathyroidism
0.000 0.529 0.471
E07.1 Dyshormogenetic goitre
0.000 0.532 0.468
E07.0 Hypersecretion of calcitonin
0.000 0.532 0.468
E20.1 Pseudohypoparathyroidism
0.000 0.533 0.467
E07.9 Disorder of thyroid, unspecified
0.000 0.535 0.464
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.541 0.459
E53.1 Pyridoxine deficiency
0.000 0.550 0.450
E53.0 Riboflavin deficiency
0.000 0.550 0.450
E53.9 Vitamin B deficiency, unspecified
0.000 0.552 0.448
E20.8 Other hypoparathyroidism
0.000 0.552 0.447
E51 Thiamine deficiency
0.000 0.553 0.446
E06.4 Drug-induced thyroiditis
0.000 0.555 0.445
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.555 0.445
E06.0 Acute thyroiditis
0.000 0.555 0.445
E20.9 Hypoparathyroidism, unspecified
0.000 0.558 0.442
E22.0 Acromegaly and pituitary gigantism
0.000 0.561 0.439
E26.0 Primary hyperaldosteronism
0.000 0.572 0.428
E55 Vitamin D deficiency
0.000 0.572 0.428
E06.1 Subacute thyroiditis
0.000 0.586 0.414
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.588 0.412
E28.9 Ovarian dysfunction, unspecified
0.000 0.589 0.411
E28.8 Other ovarian dysfunction
0.000 0.589 0.411
E28.1 Androgen excess
0.000 0.589 0.411
E28.0 Oestrogen excess
0.000 0.589 0.411
E07.8 Other specified disorders of thyroid
0.000 0.592 0.407
D52.8 Other folate deficiency anaemias
0.000 0.595 0.405
D52.1 Drug-induced folate deficiency anaemia
0.000 0.595 0.405
D52.0 Dietary folate deficiency anaemia
0.000 0.595 0.405
E06.5 Other chronic thyroiditis
0.000 0.599 0.401
E61 Deficiency of other nutrient elements
0.000 0.602 0.398
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.612 0.388
E06.9 Thyroiditis, unspecified
0.000 0.613 0.387
D53.8 Other specified nutritional anaemias
0.000 0.619 0.381
D53.2 Scorbutic anaemia
0.000 0.619 0.381
D53.0 Protein deficiency anaemia
0.000 0.619 0.381
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.623 0.377
D52.9 Folate deficiency anaemia, unspecified
0.000 0.624 0.376
K90 Intestinal malabsorption
0.000 0.626 0.374
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.631 0.369
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.631 0.369
E16.4 Abnormal secretion of gastrin
0.000 0.631 0.369
E16.3 Increased secretion of glucagon
0.000 0.631 0.369
E16.2 Hypoglycaemia, unspecified
0.000 0.635 0.365
E16.1 Other hypoglycaemia
0.000 0.636 0.364
E44.1 Mild protein-energy malnutrition
0.000 0.637 0.363
E44.0 Moderate protein-energy malnutrition
0.000 0.637 0.363
E28.2 Polycystic ovarian syndrome
0.000 0.637 0.363
K52 Other non-infective gastro-enteritis and colitis
0.000 0.641 0.359
E50.9 Vitamin A deficiency, unspecified
0.000 0.642 0.357
E50.8 Other manifestations of vitamin A deficiency
0.000 0.642 0.357
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.642 0.357
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.642 0.357
E50.5 Vitamin A deficiency with night blindness
0.000 0.642 0.357
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.642 0.357
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.642 0.357
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.642 0.357
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.642 0.357
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.642 0.357
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.642 0.357
E64.8 Sequelae of other nutritional deficiencies
0.000 0.642 0.357
E64.3 Sequelae of rickets
0.000 0.642 0.357
E64.2 Sequelae of vitamin C deficiency
0.000 0.642 0.357
E64.1 Sequelae of vitamin A deficiency
0.000 0.642 0.357
E64.0 Sequelae of protein-energy malnutrition
0.000 0.642 0.357
E56.9 Vitamin deficiency, unspecified
0.000 0.650 0.350
E56.8 Deficiency of other vitamins
0.000 0.650 0.350
E56.0 Deficiency of vitamin E
0.000 0.650 0.350
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.657 0.343
E63.8 Other specified nutritional deficiencies
0.000 0.659 0.341
E63.1 Imbalance of constituents of food intake
0.000 0.659 0.341
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.659 0.341
E56.1 Deficiency of vitamin K
0.000 0.660 0.340
E28.3 Primary ovarian failure
0.000 0.663 0.336
E51.9 Thiamine deficiency, unspecified
0.000 0.680 0.320
E51.8 Other manifestations of thiamine deficiency
0.000 0.680 0.320
E51.1 Beriberi
0.000 0.680 0.320
E63.9 Nutritional deficiency, unspecified
0.000 0.681 0.318
E65-E68 Obesity and other hyperalimentation
0.000 0.685 0.315
E55.0 Rickets, active
0.000 0.693 0.307
K90.8 Other intestinal malabsorption
0.000 0.709 0.291
E14.3 With ophthalmic complications
0.000 0.712 0.288
E61.9 Deficiency of nutrient element, unspecified
0.000 0.715 0.285
E61.8 Deficiency of other specified nutrient elements
0.000 0.715 0.285
E61.7 Deficiency of multiple nutrient elements
0.000 0.715 0.285
E61.6 Vanadium deficiency
0.000 0.715 0.285
E61.5 Molybdenum deficiency
0.000 0.715 0.285
E61.4 Chromium deficiency
0.000 0.715 0.285
E61.3 Manganese deficiency
0.000 0.715 0.285
E61.0 Copper deficiency
0.000 0.715 0.285
K90.9 Intestinal malabsorption, unspecified
0.000 0.725 0.275
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.730 0.270
E61.2 Magnesium deficiency
0.000 0.731 0.269
E51.2 Wernicke's encephalopathy
0.000 0.731 0.268
K90.3 Pancreatic steatorrhoea
0.000 0.732 0.268
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.732 0.268
K90.1 Tropical sprue
0.000 0.732 0.268
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.734 0.266
E04 Other non-toxic goitre
0.000 0.736 0.264
D53.9 Nutritional anaemia, unspecified
0.001 0.739 0.260
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.740 0.260
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.745 0.255
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.748 0.252
E70-E90 Metabolic disorders
0.000 0.763 0.237
E55.9 Vitamin D deficiency, unspecified
0.000 0.764 0.236
E67 Other hyperalimentation
0.000 0.774 0.226
E68 Sequelae of hyperalimentation
0.000 0.774 0.226
K52.3 Indeterminate colitis
0.000 0.778 0.222
K90-K93 Other diseases of the digestive system
0.000 0.780 0.220
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.785 0.214
E83 Disorders of mineral metabolism
0.000 0.788 0.212
E61.1 Iron deficiency
0.000 0.789 0.211
E04.0 Non-toxic diffuse goitre
0.000 0.791 0.209
E89.0 Postprocedural hypothyroidism
0.000 0.795 0.205
E83.1 Disorders of iron metabolism
0.000 0.795 0.205
Chapter XI Diseases of the digestive system
0.000 0.796 0.204
E85 Amyloidosis
0.000 0.798 0.202
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.000 0.800 0.200
K07 Dentofacial anomalies [including malocclusion]
0.000 0.801 0.199
K07.3 Anomalies of tooth position
0.000 0.802 0.198
K11 Diseases of salivary glands
0.000 0.802 0.198
E04.8 Other specified non-toxic goitre
0.000 0.810 0.190
K11.2 Sialoadenitis
0.000 0.816 0.184
E84 Cystic fibrosis
0.000 0.822 0.178
K11.5 Sialolithiasis
0.000 0.823 0.177
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.823 0.177
E70 Disorders of aromatic amino-acid metabolism
0.000 0.825 0.175
E74 Other disorders of carbohydrate metabolism
0.000 0.826 0.173
K09 Cysts of oral region, not elsewhere classified
0.000 0.827 0.173
K12 Stomatitis and related lesions
0.000 0.828 0.172
E76 Disorders of glycosaminoglycan metabolism
0.000 0.830 0.170
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.830 0.170
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.830 0.170
E89.5 Postprocedural testicular hypofunction
0.000 0.832 0.168
E89.1 Postprocedural hypoinsulinaemia
0.000 0.832 0.168
E85.9 Amyloidosis, unspecified
0.000 0.833 0.167
K11.9 Disease of salivary gland, unspecified
0.000 0.834 0.166
E79 Disorders of purine and pyrimidine metabolism
0.000 0.834 0.166
E77 Disorders of glycoprotein metabolism
0.000 0.835 0.165
E67.8 Other specified hyperalimentation
0.000 0.838 0.162
E67.3 Hypervitaminosis D
0.000 0.838 0.162
E67.2 Megavitamin-B6 syndrome
0.000 0.838 0.162
E67.1 Hypercarotenaemia
0.000 0.838 0.162
E67.0 Hypervitaminosis A
0.000 0.838 0.162
K11.1 Hypertrophy of salivary gland
0.000 0.839 0.161
E83.4 Disorders of magnesium metabolism
0.000 0.839 0.161
K07.4 Malocclusion, unspecified
0.000 0.840 0.159
K12.1 Other forms of stomatitis
0.000 0.841 0.159
E85.8 Other amyloidosis
0.000 0.842 0.158
K07.1 Anomalies of jaw-cranial base relationship
0.000 0.842 0.158
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.842 0.158
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.844 0.156
K09.0 Developmental odontogenic cysts
0.000 0.845 0.155
E85.3 Secondary systemic amyloidosis
0.000 0.845 0.154
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.846 0.154
K11.3 Abscess of salivary gland
0.000 0.847 0.153
E83.8 Other disorders of mineral metabolism
0.000 0.848 0.152
E83.2 Disorders of zinc metabolism
0.000 0.848 0.152
E83.0 Disorders of copper metabolism
0.000 0.848 0.152
E72 Other disorders of amino-acid metabolism
0.000 0.848 0.152
K07.9 Dentofacial anomaly, unspecified
0.000 0.848 0.152
K07.0 Major anomalies of jaw size
0.000 0.848 0.152
E89.2 Postprocedural hypoparathyroidism
0.000 0.848 0.152
E73 Lactose intolerance
0.000 0.850 0.150
K03 Other diseases of hard tissues of teeth
0.000 0.850 0.150
K00 Disorders of tooth development and eruption
0.000 0.851 0.148
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.852 0.148
K04 Diseases of pulp and periapical tissues
0.000 0.853 0.147
E65 Localised adiposity
0.001 0.853 0.146
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.855 0.145
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.855 0.145
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.855 0.145
K11.0 Atrophy of salivary gland
0.000 0.855 0.144
K07.5 Dentofacial functional abnormalities
0.000 0.857 0.143
K11.4 Fistula of salivary gland
0.000 0.858 0.142
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.860 0.140
K14 Diseases of tongue
0.000 0.860 0.140
E85.4 Organ-limited amyloidosis
0.000 0.861 0.139
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.862 0.138
K04.8 Radicular cyst
0.000 0.864 0.136
K07.6 Temporomandibular joint disorders
0.000 0.864 0.136
K09.8 Other cysts of oral region, not elsewhere classified
0.000 0.865 0.135
E89.3 Postprocedural hypopituitarism
0.000 0.865 0.135
K12.0 Recurrent oral aphthae
0.000 0.866 0.134
E84.9 Cystic fibrosis, unspecified
0.000 0.866 0.133
K11.7 Disturbances of salivary secretion
0.000 0.868 0.132
E83.5 Disorders of calcium metabolism
0.000 0.868 0.132
K07.8 Other dentofacial anomalies
0.000 0.868 0.132
E89.4 Postprocedural ovarian failure
0.000 0.868 0.131
E75.2 Other sphingolipidosis
0.000 0.869 0.131
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.869 0.130
E70.3 Albinism
0.000 0.869 0.130
E75.5 Other lipid storage disorders
0.000 0.870 0.130
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.870 0.130
K11.8 Other diseases of salivary glands
0.000 0.871 0.129
E04.9 Non-toxic goitre, unspecified
0.000 0.871 0.129
K06 Other disorders of gingiva and edentulous alveolar ridge
0.000 0.872 0.128
E84.8 Cystic fibrosis with other manifestations
0.000 0.872 0.128
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.872 0.128
E75.6 Lipid storage disorder, unspecified
0.000 0.873 0.127
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.873 0.127
E75.3 Sphingolipidosis, unspecified
0.000 0.873 0.127
E75.1 Other gangliosidosis
0.000 0.873 0.127
E75.0 GM2 gangliosidosis
0.000 0.873 0.127
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.874 0.126
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.874 0.126
E70.2 Disorders of tyrosine metabolism
0.000 0.874 0.126
E70.1 Other hyperphenylalaninaemias
0.000 0.874 0.126
E70.0 Classical phenylketonuria
0.000 0.874 0.126
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.875 0.124
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.875 0.124
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.875 0.124
E74.2 Disorders of galactose metabolism
0.000 0.875 0.124
E74.1 Disorders of fructose metabolism
0.000 0.875 0.124
K00.0 Anodontia
0.000 0.876 0.124
K10 Other diseases of jaws
0.000 0.876 0.124
K09.9 Cyst of oral region, unspecified
0.000 0.876 0.124
K04.4 Acute apical periodontitis of pulpal origin
0.000 0.877 0.123
K07.2 Anomalies of dental arch relationship
0.000 0.877 0.122
E71.3 Disorders of fatty-acid metabolism
0.000 0.878 0.122
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.878 0.122
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.878 0.122
E71.0 Maple-syrup-urine disease
0.000 0.878 0.122
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.878 0.122
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.878 0.122
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.878 0.122
E76.2 Other mucopolysaccharidoses
0.000 0.878 0.122
E76.1 Mucopolysaccharidosis, type II
0.000 0.878 0.122
E76.0 Mucopolysaccharidosis, type I
0.000 0.878 0.122
K09.1 Developmental (nonodontogenic) cysts of oral region
0.000 0.878 0.122
E87.3 Alkalosis
0.000 0.879 0.121
K14.8 Other diseases of tongue
0.000 0.880 0.120
K11.6 Mucocele of salivary gland
0.000 0.881 0.119
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.881 0.119
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.881 0.119
E79.1 Lesch-Nyhan syndrome
0.000 0.881 0.119
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.881 0.118
E77.1 Defects in glycoprotein degradation
0.000 0.881 0.118
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.881 0.118
K52.1 Toxic gastro-enteritis and colitis
0.001 0.883 0.116
K04.5 Chronic apical periodontitis
0.000 0.884 0.116
K03.8 Other specified diseases of hard tissues of teeth
0.000 0.884 0.116
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.885 0.115
E87.0 Hyperosmolality and hypernatraemia
0.000 0.885 0.115
E04.2 Non-toxic multinodular goitre
0.000 0.885 0.115
K03.9 Disease of hard tissues of teeth, unspecified
0.000 0.886 0.114
E77.8 Other disorders of glycoprotein metabolism
0.000 0.886 0.113
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.887 0.113
K93.1 Megacolon in Chagas' disease
0.000 0.887 0.113
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.887 0.113
K09.2 Other cysts of jaw
0.000 0.887 0.113
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.000 0.889 0.111
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.891 0.109
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.891 0.109
E72.5 Disorders of glycine metabolism
0.000 0.891 0.109
E72.4 Disorders of ornithine metabolism
0.000 0.891 0.109
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.891 0.109
E72.2 Disorders of urea cycle metabolism
0.000 0.891 0.109
K00.1 Supernumerary teeth
0.000 0.892 0.108
E73.8 Other lactose intolerance
0.000 0.892 0.107
E73.1 Secondary lactase deficiency
0.000 0.892 0.107
E73.0 Congenital lactase deficiency
0.000 0.892 0.107
K03.7 Posteruptive colour changes of dental hard tissues
0.000 0.892 0.107
K03.5 Ankylosis of teeth
0.000 0.892 0.107
K03.4 Hypercementosis
0.000 0.892 0.107
K03.2 Erosion of teeth
0.000 0.892 0.107
K03.1 Abrasion of teeth
0.000 0.892 0.107
K03.0 Excessive attrition of teeth
0.000 0.892 0.107
E74.0 Glycogen storage disease
0.000 0.893 0.107
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.893 0.107
K12.3 Oral mucositis (ulcerative)
0.000 0.893 0.107
K00.7 Teething syndrome
0.000 0.893 0.107
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified
0.000 0.893 0.107
K00.4 Disturbances in tooth formation
0.000 0.893 0.107
K00.3 Mottled teeth
0.000 0.893 0.107
K00.2 Abnormalities of size and form of teeth
0.000 0.893 0.107
K14.9 Disease of tongue, unspecified
0.000 0.893 0.107
K04.3 Abnormal hard tissue formation in pulp
0.000 0.894 0.106
K04.2 Pulp degeneration
0.000 0.894 0.106
K04.1 Necrosis of pulp
0.000 0.894 0.106
K00.8 Other disorders of tooth development
0.000 0.894 0.105

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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