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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28530674
log Bayes Factor = <0.0001
Chromosome 1   position 19,234,134  (GRCh37) Explore rs28530674 on Ensembl!
Variant rs28530674 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M65.34 Trigger finger-Hand
0.047 0.953 0.000
M65.3 Trigger finger
0.042 0.958 0.000
M65 Synovitis and tenosynovitis
0.039 0.961 0.000
M65.8 Other synovitis and tenosynovitis
0.034 0.966 0.000
M65.1 Other infective (teno)synovitis
0.033 0.967 0.000
M65.39 Trigger finger-Site unspec
0.030 0.970 0.000
M65.38 Trigger finger-Other
0.030 0.970 0.000
M65.37 Trigger finger-Ankle/foot
0.030 0.970 0.000
M65.36 Trigger finger-Lower leg
0.030 0.970 0.000
M65.35 Trigger finger-Pelvic/thigh
0.030 0.970 0.000
M65.33 Trigger finger-Forearm
0.030 0.970 0.000
M65.32 Trigger finger-Upper arm
0.030 0.970 0.000
M65.31 Trigger finger-Shldr region
0.030 0.970 0.000
M65.30 Trigger finger-Mult sites
0.030 0.970 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.030 0.970 0.000
M65.83 Other synovitis and tenosynovitis (Forearm)
0.029 0.971 0.000
M65.14 Other infective (teno)synovitis (Hand)
0.029 0.971 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.029 0.971 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.028 0.971 0.000
M65.2 Calcific tendinitis
0.028 0.972 0.000
M65.0 Abscess of tendon sheath
0.028 0.972 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.026 0.974 0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)
0.025 0.975 0.000
M65.88 Other synovitis and tenosynovitis (Other)
0.025 0.975 0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)
0.025 0.975 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.025 0.975 0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)
0.025 0.975 0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)
0.025 0.975 0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)
0.025 0.975 0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)
0.025 0.975 0.000
M65-M68 Disorders of synovium and tendon
0.025 0.975 0.000
M65.19 Other infective (teno)synovitis (Site unspecified)
0.024 0.976 0.000
M65.18 Other infective (teno)synovitis (Other)
0.024 0.976 0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)
0.024 0.976 0.000
M65.16 Other infective (teno)synovitis (Lower leg)
0.024 0.976 0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)
0.024 0.976 0.000
M65.13 Other infective (teno)synovitis (Forearm)
0.024 0.976 0.000
M65.12 Other infective (teno)synovitis (Upper arm)
0.024 0.976 0.000
M65.11 Other infective (teno)synovitis (Shoulder region)
0.024 0.976 0.000
M65.10 Other infective (teno)synovitis (Multiple sites)
0.024 0.976 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.022 0.978 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.022 0.978 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.021 0.978 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.021 0.978 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.021 0.978 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.021 0.978 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.021 0.978 0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.021 0.979 0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.021 0.979 0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.021 0.979 0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.021 0.979 0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.021 0.979 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.021 0.979 0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.021 0.979 0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.021 0.979 0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.021 0.979 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.021 0.979 0.000
M65.09 Abscess of tendon sheath (Site unspecified)
0.020 0.980 0.000
M65.08 Abscess of tendon sheath (Other)
0.020 0.980 0.000
M65.07 Abscess of tendon sheath (Ankle and foot)
0.020 0.980 0.000
M65.06 Abscess of tendon sheath (Lower leg)
0.020 0.980 0.000
M65.05 Abscess of tendon sheath (Pelvic region and thigh)
0.020 0.980 0.000
M65.04 Abscess of tendon sheath (Hand)
0.020 0.980 0.000
M65.03 Abscess of tendon sheath (Forearm)
0.020 0.980 0.000
M65.02 Abscess of tendon sheath (Upper arm)
0.020 0.980 0.000
M65.01 Abscess of tendon sheath (Shoulder region)
0.020 0.980 0.000
M65.00 Abscess of tendon sheath (Multiple sites)
0.020 0.980 0.000
M65.29 Calcific tendinitis (Site unspecified)
0.020 0.980 0.000
M65.28 Calcific tendinitis (Other)
0.020 0.980 0.000
M65.27 Calcific tendinitis (Ankle and foot)
0.020 0.980 0.000
M65.26 Calcific tendinitis (Lower leg)
0.020 0.980 0.000
M65.25 Calcific tendinitis (Pelvic region and thigh)
0.020 0.980 0.000
M65.24 Calcific tendinitis (Hand)
0.020 0.980 0.000
M65.23 Calcific tendinitis (Forearm)
0.020 0.980 0.000
M65.22 Calcific tendinitis (Upper arm)
0.020 0.980 0.000
M65.21 Calcific tendinitis (Shoulder region)
0.020 0.980 0.000
M65.20 Calcific tendinitis (Multiple sites)
0.020 0.980 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.019 0.980 0.000
M66 Spontaneous rupture of synovium and tendon
0.019 0.981 0.000
M51.2 Other specified intervertebral disk displacement
0.019 0.981 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.018 0.982 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.018 0.982 0.000
M67 Other disorders of synovium and tendon
0.017 0.983 0.000
M51 Other intervertebral disk disorders
0.015 0.985 0.000
M24.07 Loose body in joint (Ankle and foot)
0.015 0.985 0.000
M66.0 Rupture of popliteal cyst
0.015 0.985 0.000
M24.0 Loose body in joint
0.014 0.986 0.000
M66.5 Spontaneous rupture of unspecified tendon
0.014 0.986 0.000
M66.4 Spontaneous rupture of other tendons
0.014 0.986 0.000
M66.3 Spontaneous rupture of flexor tendons
0.014 0.986 0.000
M66.2 Spontaneous rupture of extensor tendons
0.014 0.986 0.000
M66.1 Rupture of synovium
0.014 0.986 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.014 0.986 0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere
0.013 0.987 0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere
0.013 0.987 0.000
M24 Other specific joint derangements
0.013 0.987 0.000
M50-M54 Other dorsopathies
0.013 0.987 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.012 0.987 0.000
M67.4 Ganglion
0.012 0.987 0.000
M67.3 Transient synovitis
0.012 0.987 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.012 0.987 0.000
M67.1 Other contracture of tendon (sheath)
0.012 0.987 0.000
M67.0 Short Achilles tendon (acquired)
0.012 0.987 0.000
M66.06 Rupture of popliteal cyst-Lower leg
0.012 0.988 0.000
M24.02 Loose body in joint (Upper arm)
0.012 0.988 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.012 0.988 0.000
M67.8 Other specified disorders of synovium and tendon
0.012 0.988 0.000
M51.8 Other specified intervertebral disk disorders
0.012 0.988 0.000
M20-M25 Other joint disorders
0.012 0.988 0.000
M51.3 Other specified intervertebral disk degeneration
0.011 0.989 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.011 0.989 0.000
M51.4 Schmorl's nodes
0.011 0.989 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.011 0.989 0.000
M66.09 Rupture of popliteal cyst-Site unspec
0.011 0.989 0.000
M66.08 Rupture of popliteal cyst-Other
0.011 0.989 0.000
M66.07 Rupture of popliteal cyst-Ankle/foot
0.011 0.989 0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh
0.011 0.989 0.000
M66.04 Rupture of popliteal cyst-Hand
0.011 0.989 0.000
M66.03 Rupture of popliteal cyst-Forearm
0.011 0.989 0.000
M66.02 Rupture of popliteal cyst-Upper arm
0.011 0.989 0.000
M66.01 Rupture of popliteal cyst-Shldr region
0.011 0.989 0.000
M66.00 Rupture of popliteal cyst-Mult sites
0.011 0.989 0.000
M60-M63 Disorders of muscles
0.011 0.989 0.000
M86-M90 Other osteopathies
0.011 0.989 0.000
M45-M49 Spondylopathies
0.011 0.989 0.000
M51.9 Intervertebral disk disorder, unspecified
0.010 0.989 0.000
M24.09 Loose body in joint (Site unspecified)
0.010 0.989 0.000
M24.08 Loose body in joint (Other)
0.010 0.989 0.000
M24.06 Loose body in joint-Lower leg
0.010 0.989 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.010 0.989 0.000
M24.04 Loose body in joint (Hand)
0.010 0.989 0.000
M24.03 Loose body in joint (Forearm)
0.010 0.989 0.000
M24.01 Loose body in joint (Shoulder region)
0.010 0.989 0.000
M24.00 Loose body in joint (Multiple sites)
0.010 0.989 0.000
M24.5 Contracture of joint
0.010 0.990 0.000
M21 Other acquired deformities of limbs
0.010 0.990 0.000
M66.19 Rupture of synovium (Site unspecified)
0.010 0.990 0.000
M66.18 Rupture of synovium (Other)
0.010 0.990 0.000
M66.17 Rupture of synovium (Ankle and foot)
0.010 0.990 0.000
M66.16 Rupture of synovium (Lower leg)
0.010 0.990 0.000
M66.15 Rupture of synovium (Pelvic region and thigh)
0.010 0.990 0.000
M66.14 Rupture of synovium (Hand)
0.010 0.990 0.000
M66.13 Rupture of synovium (Forearm)
0.010 0.990 0.000
M66.12 Rupture of synovium (Upper arm)
0.010 0.990 0.000
M66.11 Rupture of synovium (Shoulder region)
0.010 0.990 0.000
M66.10 Rupture of synovium (Multiple sites)
0.010 0.990 0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)
0.010 0.990 0.000
M66.28 Spontaneous rupture of extensor tendons-Other
0.010 0.990 0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)
0.010 0.990 0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)
0.010 0.990 0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)
0.010 0.990 0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)
0.010 0.990 0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)
0.010 0.990 0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)
0.010 0.990 0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)
0.010 0.990 0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)
0.010 0.990 0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)
0.010 0.990 0.000
M66.38 Spontaneous rupture of flexor tendons (Other)
0.010 0.990 0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)
0.010 0.990 0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)
0.010 0.990 0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)
0.010 0.990 0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)
0.010 0.990 0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)
0.010 0.990 0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)
0.010 0.990 0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)
0.010 0.990 0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)
0.010 0.990 0.000
M66.49 Spontaneous rupture of other tendons (Site unspecified)
0.010 0.990 0.000
M66.48 Spontaneous rupture of other tendons (Other)
0.010 0.990 0.000
M66.47 Spontaneous rupture of other tendons (Ankle and foot)
0.010 0.990 0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)
0.010 0.990 0.000
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)
0.010 0.990 0.000
M66.44 Spontaneous rupture of other tendons (Hand)
0.010 0.990 0.000
M66.43 Spontaneous rupture of other tendons (Forearm)
0.010 0.990 0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)
0.010 0.990 0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)
0.010 0.990 0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)
0.010 0.990 0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)
0.010 0.990 0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)
0.010 0.990 0.000
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)
0.010 0.990 0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)
0.010 0.990 0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)
0.010 0.990 0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)
0.010 0.990 0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)
0.010 0.990 0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)
0.010 0.990 0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)
0.010 0.990 0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)
0.010 0.990 0.000
M91-M94 Chondropathies
0.010 0.990 0.000
M20 Acquired deformities of fingers and toes
0.010 0.990 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.010 0.990 0.000
M40-M43 Deforming dorsopathies
0.010 0.990 0.000
M24.2 Disorder of ligament
0.010 0.990 0.000
M00-M03 Infectious arthropathies
0.010 0.990 0.000
M20.2 Hallux rigidus
0.010 0.990 0.000
M24.9 Joint derangement, unspecified
0.009 0.990 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.009 0.990 0.000
M24.7 Protrusio acetabuli
0.009 0.990 0.000
M24.6 Ankylosis of joint
0.009 0.990 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.009 0.990 0.000
M24.1 Other articular cartilage disorders
0.009 0.990 0.000
M32 Systemic lupus erythematosus
0.009 0.991 0.000
M67.49 Ganglion, multiple sites
0.009 0.991 0.000
M67.47 Ganglion, ankle and foot
0.009 0.991 0.000
M67.45 Ganglion, hip
0.009 0.991 0.000
M67.43 Ganglion, wrist
0.009 0.991 0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg
0.009 0.991 0.000
M53 Other dorsopathies, not elsewhere classified
0.009 0.991 0.000
M45 Ankylosing spondylitis
0.009 0.991 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.009 0.991 0.000
M34 Systemic sclerosis
0.009 0.991 0.000
M62 Other disorders of muscle
0.009 0.991 0.000
M47 Spondylosis
0.009 0.991 0.000
M86 Osteomyelitis
0.009 0.991 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.009 0.991 0.000
M70-M79 Other soft tissue disorders
0.009 0.991 0.000
M24.51 Contracture of joint (Shoulder region)
0.009 0.991 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.009 0.991 0.000
M33 Dermatopolymyositis
0.009 0.991 0.000
M30 Polyarteritis nodosa and related conditions
0.009 0.991 0.000
L57.0 Actinic keratosis
0.009 0.991 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.009 0.991 0.000
M21.6 Other acquired deformities of ankle and foot
0.008 0.991 0.000
M21.0 Valgus deformity, not elsewhere classified
0.008 0.991 0.000
M20.4 Other hammer toe(s) (acquired)
0.008 0.992 0.000
M05-M14 Inflammatory polyarthropathies
0.008 0.992 0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified
0.008 0.992 0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region
0.008 0.992 0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region
0.008 0.992 0.000
M31 Other necrotising vasculopathies
0.008 0.992 0.000
M99 Biomechanical lesions, not elsewhere classified
0.008 0.992 0.000
M90 Osteopathies in diseases classified elsewhere
0.008 0.992 0.000
M21.3 Wrist or foot drop (acquired)
0.008 0.992 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.008 0.992 0.000
M80-M85 Disorders of bone density and structure
0.008 0.992 0.000
M20.3 Other deformity of hallux (acquired)
0.008 0.992 0.000
M87 Osteonecrosis
0.008 0.992 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.008 0.992 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.008 0.992 0.000
M61 Calcification and ossification of muscle
0.008 0.992 0.000
M60 Myositis
0.008 0.992 0.000
M49 Spondylopathies in diseases classified elsewhere
0.008 0.992 0.000
M89 Other disorders of bone
0.008 0.992 0.000
M40 Kyphosis and lordosis
0.008 0.992 0.000
M92 Other juvenile osteochondrosis
0.008 0.992 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.008 0.992 0.000
M24.59 Contracture of joint (Site unspecified)
0.008 0.992 0.000
M24.58 Contracture of joint (Other)
0.008 0.992 0.000
M24.57 Contracture of joint (Ankle and foot)
0.008 0.992 0.000
M24.56 Contracture of joint (Lower leg)
0.008 0.992 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.008 0.992 0.000
M24.54 Contracture of joint (Hand)
0.008 0.992 0.000
M24.53 Contracture of joint (Forearm)
0.008 0.992 0.000
M24.52 Contracture of joint (Upper arm)
0.008 0.992 0.000
M24.50 Contracture of joint (Multiple sites)
0.008 0.992 0.000
M46 Other inflammatory spondylopathies
0.008 0.992 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.008 0.992 0.000
M21.9 Acquired deformity of limb, unspecified
0.008 0.992 0.000
M21.8 Other specified acquired deformities of limbs
0.008 0.992 0.000
M21.7 Unequal limb length (acquired)
0.008 0.992 0.000
M21.4 Flat foot [pes planus] (acquired)
0.008 0.992 0.000
M21.2 Flexion deformity
0.008 0.992 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.008 0.992 0.000
M88 Paget's disease of bone [osteitis deformans]
0.007 0.992 0.000
M47.82 Other spondylosis (Cervical region)
0.008 0.992 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.008 0.992 0.000
M24.23 Disorder of ligament (Forearm)
0.007 0.992 0.000
M93 Other osteochondropathies
0.007 0.992 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.007 0.992 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.008 0.992 0.000
M62.8 Other specified disorders of muscle
0.007 0.992 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.007 0.993 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.007 0.993 0.000
M50 Cervical disk disorders
0.007 0.993 0.000
M47.8 Other spondylosis
0.007 0.993 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.007 0.993 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.007 0.993 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.007 0.993 0.000
M96.5 Postradiation scoliosis
0.007 0.993 0.000
M96.4 Postsurgical lordosis
0.007 0.993 0.000
M96.3 Postlaminectomy kyphosis
0.007 0.993 0.000
M96.2 Postradiation kyphosis
0.007 0.993 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.007 0.993 0.000
M21.1 Varus deformity, not elsewhere classified
0.007 0.993 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.007 0.993 0.000
M86.9 Osteomyelitis, unspecified
0.007 0.993 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.007 0.993 0.000
M42 Spinal osteochondrosis
0.007 0.993 0.000
M94 Other disorders of cartilage
0.007 0.993 0.000
M24.29 Disorder of ligament (Site unspecified)
0.007 0.993 0.000
M24.28 Disorder of ligament (Other)
0.007 0.993 0.000
M24.26 Disorder of ligament (Lower leg)
0.007 0.993 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.007 0.993 0.000
M24.24 Disorder of ligament (Hand)
0.007 0.993 0.000
M24.22 Disorder of ligament (Upper arm)
0.007 0.993 0.000
M24.21 Disorder of ligament (Shoulder region)
0.007 0.993 0.000
M24.20 Disorder of ligament (Multiple sites)
0.007 0.993 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.007 0.993 0.000
M02 Reactive arthropathies
0.007 0.993 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.007 0.993 0.000
Y40 Systemic antibiotics
0.007 0.993 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.007 0.993 0.000
M47.9 Spondylosis, unspecified
0.007 0.993 0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)
0.007 0.993 0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)
0.007 0.993 0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.007 0.993 0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)
0.007 0.993 0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)
0.007 0.993 0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)
0.007 0.993 0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)
0.007 0.993 0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)
0.007 0.993 0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)
0.007 0.993 0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)
0.007 0.993 0.000
M24.69 Ankylosis of joint (Site unspecified)
0.007 0.993 0.000
M24.68 Ankylosis of joint (Other)
0.007 0.993 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.007 0.993 0.000
M24.66 Ankylosis of joint (Lower leg)
0.007 0.993 0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)
0.007 0.993 0.000
M24.64 Ankylosis of joint (Hand)
0.007 0.993 0.000
M24.63 Ankylosis of joint (Forearm)
0.007 0.993 0.000
M24.62 Ankylosis of joint (Upper arm)
0.007 0.993 0.000
M24.61 Ankylosis of joint (Shoulder region)
0.007 0.993 0.000
M24.60 Ankylosis of joint (Multiple sites)
0.007 0.993 0.000
M24.79 Protrusio acetabuli-Site unspec
0.007 0.993 0.000
M24.78 Protrusio acetabuli-Other
0.007 0.993 0.000
M24.77 Protrusio acetabuli-Ankle/foot
0.007 0.993 0.000
M24.76 Protrusio acetabuli-Lower leg
0.007 0.993 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.007 0.993 0.000
M24.74 Protrusio acetabuli-Hand
0.007 0.993 0.000
M24.73 Protrusio acetabuli-Forearm
0.007 0.993 0.000
M24.72 Protrusio acetabuli-Upper arm
0.007 0.993 0.000
M24.71 Protrusio acetabuli-Shldr region
0.007 0.993 0.000
M24.70 Protrusio acetabuli-Mult sites
0.007 0.993 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.007 0.993 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.007 0.993 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.007 0.993 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.007 0.993 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.007 0.993 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.007 0.993 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.007 0.993 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.007 0.993 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.007 0.993 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.007 0.993 0.000
M24.99 Joint derangement, unspecified (Site unspecified)
0.007 0.993 0.000
M24.98 Joint derangement, unspecified (Other)
0.007 0.993 0.000
M24.97 Joint derangement, unspecified (Ankle and foot)
0.007 0.993 0.000
M24.96 Joint derangement, unspecified (Lower leg)
0.007 0.993 0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)
0.007 0.993 0.000
M24.94 Joint derangement, unspecified (Hand)
0.007 0.993 0.000
M24.93 Joint derangement, unspecified (Forearm)
0.007 0.993 0.000
M24.92 Joint derangement, unspecified (Upper arm)
0.007 0.993 0.000
M24.91 Joint derangement, unspecified (Shoulder region)
0.007 0.993 0.000
M24.90 Joint derangement, unspecified (Multiple sites)
0.007 0.993 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.007 0.993 0.000
M24.18 Other articular cartilage disorders (Other)
0.007 0.993 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.007 0.993 0.000
M24.14 Other articular cartilage disorders (Hand)
0.007 0.993 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.007 0.993 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.007 0.993 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.007 0.993 0.000
M34.9 Systemic sclerosis, unspecified
0.007 0.993 0.000
M79.0 Rheumatism, unspecified
0.007 0.993 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.007 0.993 0.000
M32.8 Other forms of systemic lupus erythematosus
0.007 0.993 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.007 0.993 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.007 0.993 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.007 0.993 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.007 0.993 0.000
M06 Other rheumatoid arthritis
0.007 0.993 0.000
M53.9 Dorsopathy, unspecified
0.007 0.993 0.000
M53.8 Other specified dorsopathies
0.007 0.993 0.000
M53.2 Spinal instabilities
0.007 0.993 0.000
M53.1 Cervicobrachial syndrome
0.007 0.993 0.000
M53.0 Cervicocranial syndrome
0.007 0.993 0.000
M20.0 Deformity of finger(s)
0.007 0.993 0.000
M35 Other systemic involvement of connective tissue
0.007 0.993 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.007 0.993 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.007 0.993 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.007 0.993 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.007 0.993 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.007 0.993 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.007 0.993 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.007 0.993 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.007 0.993 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.007 0.993 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.007 0.993 0.000
M00 Pyogenic arthritis
0.007 0.993 0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.007 0.993 0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.007 0.993 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.007 0.993 0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.007 0.993 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.007 0.993 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.007 0.993 0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.007 0.993 0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)
0.007 0.993 0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)
0.007 0.993 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.007 0.993 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.007 0.993 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.007 0.993 0.000
M05 Seropositive rheumatoid arthritis
0.007 0.993 0.000
M71 Other bursopathies
0.007 0.993 0.000
M41 Scoliosis
0.007 0.993 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.007 0.993 0.000
M34.8 Other forms of systemic sclerosis
0.007 0.993 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.007 0.993 0.000
M34.1 CR(E)ST syndrome
0.007 0.993 0.000
M34.0 Progressive systemic sclerosis
0.007 0.993 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.007 0.993 0.000
M31.3 Wegener's granulomatosis
0.007 0.993 0.000
M07 Psoriatic and enteropathic arthropathies
0.007 0.993 0.000
M62.9 Disorder of muscle, unspecified
0.006 0.993 0.000
M62.6 Muscle strain
0.006 0.993 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.006 0.993 0.000
M62.4 Contracture of muscle
0.006 0.993 0.000
M62.3 Immobility syndrome (paraplegic)
0.006 0.993 0.000
M62.2 Ischaemic infarction of muscle
0.006 0.993 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.006 0.993 0.000
M62.0 Diastasis of muscle
0.006 0.993 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.006 0.993 0.000
M40.2 Other and unspecified kyphosis
0.006 0.993 0.000
M85 Other disorders of bone density and structure
0.006 0.993 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.006 0.993 0.000
Y40.8 Other systemic antibiotics
0.007 0.993 0.000
M43 Other deforming dorsopathies
0.006 0.993 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.006 0.993 0.000
M86.8 Other osteomyelitis
0.006 0.993 0.000
M86.6 Other chronic osteomyelitis
0.006 0.993 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.006 0.993 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.006 0.993 0.000
M86.3 Chronic multifocal osteomyelitis
0.006 0.993 0.000
M86.2 Subacute osteomyelitis
0.006 0.993 0.000
M86.1 Other acute osteomyelitis
0.006 0.993 0.000
M86.0 Acute haematogenous osteomyelitis
0.006 0.993 0.000
M76 Enthesopathies of lower limb, excluding foot
0.006 0.993 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.006 0.993 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.006 0.993 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.006 0.993 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.006 0.993 0.000
M30.2 Juvenile polyarteritis
0.006 0.993 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.006 0.993 0.000
M30.0 Polyarteritis nodosa
0.006 0.993 0.000
M33.9 Dermatopolymyositis, unspecified
0.006 0.993 0.000
M33.2 Polymyositis
0.006 0.993 0.000
M33.1 Other dermatomyositis
0.006 0.993 0.000
M33.0 Juvenile dermatomyositis
0.006 0.993 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.006 0.993 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.006 0.993 0.000
M36.3 Arthropathy in other blood disorders
0.006 0.993 0.000
M36.2 Haemophilic arthropathy
0.006 0.993 0.000
M36.1 Arthropathy in neoplastic disease
0.006 0.993 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.006 0.993 0.000
M47.1 Other spondylosis with myelopathy
0.006 0.993 0.000
M50.3 Other cervical disk degeneration
0.006 0.993 0.000
Y54.3 Benzothiadiazine derivatives
0.006 0.993 0.000
M89.3 Hypertrophy of bone
0.006 0.994 0.000
M72 Fibroblastic disorders
0.006 0.994 0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec
0.006 0.994 0.000
M21.68 Other acquired deformities of ankle and foot-Other
0.006 0.994 0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg
0.006 0.994 0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh
0.006 0.994 0.000
M21.64 Other acquired deformities of ankle and foot-Hand
0.006 0.994 0.000
M21.63 Other acquired deformities of ankle and foot-Forearm
0.006 0.994 0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm
0.006 0.994 0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region
0.006 0.994 0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites
0.006 0.994 0.000
M90.7 Fracture of bone in neoplastic disease
0.006 0.994 0.000
Y52 Agents primarily affecting the cardiovascular system
0.006 0.994 0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)
0.006 0.994 0.000
M21.08 Valgus deformity, not elsewhere classified (Other)
0.006 0.994 0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)
0.006 0.994 0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)
0.006 0.994 0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)
0.006 0.994 0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)
0.006 0.994 0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)
0.006 0.994 0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)
0.006 0.994 0.000
M79.1 Myalgia
0.006 0.994 0.000
M79.2 Neuralgia and neuritis, unspecified
0.006 0.994 0.000
M14 Arthropathies in other diseases classified elsewhere
0.006 0.994 0.000
M12 Other specific arthropathies
0.006 0.994 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.006 0.994 0.000
M08 Juvenile arthritis
0.006 0.994 0.000
M87.9 Osteonecrosis, unspecified
0.006 0.994 0.000
M92.6 Juvenile osteochondrosis of tarsus
0.006 0.994 0.000
N43.3 Hydrocele, unspecified
0.000 0.994 0.006
M62.86 Other specified disorders of muscle (Lower leg)
0.006 0.994 0.000
M31.9 Necrotising vasculopathy, unspecified
0.006 0.994 0.000
M31.8 Other specified necrotising vasculopathies
0.006 0.994 0.000
M31.7 Microscopic polyangiitis
0.006 0.994 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.006 0.994 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.006 0.994 0.000
M31.2 Lethal midline granuloma
0.006 0.994 0.000
M31.1 Thrombotic microangiopathy
0.006 0.994 0.000
M31.0 Hypersensitivity angiitis
0.006 0.994 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.006 0.994 0.000
M48 Other spondylopathies
0.006 0.994 0.000
M79.7 Fibromyalgia
0.006 0.994 0.000
M77 Other enthesopathies
0.006 0.994 0.000
M89.8 Other specified disorders of bone
0.006 0.994 0.000
M99.9 Biomechanical lesion, unspecified
0.006 0.994 0.000
M99.8 Other biomechanical lesions
0.006 0.994 0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina
0.006 0.994 0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina
0.006 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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