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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2855812
log Bayes Factor = 350.197
Chromosome 6   position 31,472,720  (GRCh37) Explore rs2855812 on Ensembl!
Variant rs2855812 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
E14.3 With ophthalmic complications
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
E10.4 With neurological complications
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
J45 Asthma
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
K75 Other inflammatory liver diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
E11.3 With ophthalmic complications
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.999 0.001 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.999 0.001 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.999 0.001 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.999 0.001 0.000
K75.4 Autoimmune hepatitis
0.999 0.001 0.000
E89.0 Postprocedural hypothyroidism
0.999 0.001 0.000
K90.9 Intestinal malabsorption, unspecified
0.998 0.002 0.000
E10.2 With renal complications
0.998 0.002 0.000
Chapter VIII Diseases of the ear and mastoid process
0.998 0.002 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.997 0.003 0.000
H36 Retinal disorders in diseases classified elsewhere
0.997 0.003 0.000
E20-E35 Disorders of other endocrine glands
0.996 0.004 0.000
D80-D89 Certain disorders involving the immune mechanism
0.996 0.004 0.000
E06 Thyroiditis
0.996 0.004 0.000
H30-H36 Disorders of choroid and retina
0.995 0.005 0.000
M60-M63 Disorders of muscles
0.993 0.007 0.000
H60-H62 Diseases of external ear
0.992 0.008 0.000
C81 Hodgkin's disease
0.992 0.008 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.992 0.008 0.000
D61 Other aplastic anaemias
0.990 0.010 0.000
M34 Systemic sclerosis
0.990 0.010 0.000
E50-E64 Other nutritional deficiencies
0.990 0.010 0.000
D70 Agranulocytosis
0.989 0.011 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.986 0.014 0.000
D50-D53 Nutritional anaemias
0.986 0.014 0.000
Chapter VII Diseases of the eye and adnexa
0.986 0.014 0.000
E27 Other disorders of adrenal gland
0.986 0.014 0.000
Chapter IX Diseases of the circulatory system
0.983 0.017 0.000
E06.3 Autoimmune thyroiditis
0.983 0.017 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.017 0.983
I70-I79 Diseases of arteries, arterioles and capillaries
0.983 0.017 0.000
E14.9 Without complications
0.983 0.017 0.000
E10.5 With peripheral circulatory complications
0.982 0.018 0.000
M62 Other disorders of muscle
0.981 0.019 0.000
E27.1 Primary adrenocortical insufficiency
0.980 0.020 0.000
H61 Other disorders of external ear
0.978 0.022 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.977 0.023 0.000
D61.9 Aplastic anaemia, unspecified
0.975 0.025 0.000
G56 Mononeuropathies of upper limb
0.974 0.026 0.000
I73 Other peripheral vascular diseases
0.974 0.026 0.000
I60-I69 Cerebrovascular diseases
0.973 0.027 0.000
Chapter VI Diseases of the nervous system
0.972 0.028 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.970 0.030 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.968 0.032 0.000
G56.0 Carpal tunnel syndrome
0.966 0.034 0.000
C91 Lymphoid leukaemia
0.965 0.035 0.000
M62.8 Other specified disorders of muscle
0.965 0.035 0.000
H61.0 Perichondritis of external ear
0.964 0.036 0.000
G59.0 Diabetic mononeuropathy
0.964 0.036 0.000
C81.9 Hodgkin's disease, unspecified
0.962 0.038 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.962 0.038 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.962 0.038 0.000
M86-M90 Other osteopathies
0.960 0.040 0.000
K74 Fibrosis and cirrhosis of liver
0.959 0.041 0.000
E11.5 With peripheral circulatory complications
0.959 0.041 0.000
E53 Deficiency of other B group vitamins
0.956 0.044 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.956 0.044 0.000
I73.0 Raynaud's syndrome
0.955 0.045 0.000
I63 Cerebral infarction
0.954 0.046 0.000
K73 Chronic hepatitis, not elsewhere classified
0.953 0.047 0.000
D51 Vitamin B12 deficiency anaemia
0.953 0.047 0.000
H35 Other retinal disorders
0.952 0.048 0.000
C83.3 Large cell (diffuse)
0.951 0.049 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.951 0.049 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.950 0.050 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.948 0.052 0.000
J60-J70 Lung diseases due to external agents
0.945 0.055 0.000
D80 Immunodeficiency with predominantly antibody defects
0.945 0.055 0.000
J33.9 Nasal polyp, unspecified
0.945 0.055 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.944 0.056 0.000
J33 Nasal polyp
0.942 0.058 0.000
H90-H95 Other disorders of ear
0.942 0.058 0.000
K75.8 Other specified inflammatory liver diseases
0.941 0.059 0.000
H35.8 Other specified retinal disorders
0.938 0.062 0.000
E53.8 Deficiency of other specified B group vitamins
0.936 0.064 0.000
M65-M68 Disorders of synovium and tendon
0.933 0.067 0.000
M10 Gout
0.932 0.068 0.000
C85.1 B-cell lymphoma, unspecified
0.929 0.071 0.000
J30-J39 Other diseases of upper respiratory tract
0.927 0.073 0.000
M34.1 CR(E)ST syndrome
0.927 0.073 0.000
H90 Conductive and sensorineural hearing loss
0.925 0.075 0.000
D86 Sarcoidosis
0.924 0.076 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.923 0.077 0.000
J47 Bronchiectasis
0.923 0.077 0.000
J46 Status asthmaticus
0.922 0.078 0.000
C83.0 Small cell (diffuse)
0.921 0.079 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.918 0.082 0.000
M35.3 Polymyalgia rheumatica
0.917 0.083 0.000
E06.9 Thyroiditis, unspecified
0.917 0.083 0.000
C81.1 Nodular sclerosis
0.915 0.085 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.914 0.086 0.000
J33.0 Polyp of nasal cavity
0.913 0.087 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.913 0.087 0.000
I73.9 Peripheral vascular disease, unspecified
0.910 0.090 0.000
E10.8 With unspecified complications
0.909 0.091 0.000
E89.3 Postprocedural hypopituitarism
0.906 0.094 0.000
M86 Osteomyelitis
0.903 0.097 0.000
D86.9 Sarcoidosis, unspecified
0.902 0.098 0.000
E10.0 With coma
0.902 0.098 0.000
J69 Pneumonitis due to solids and liquids
0.899 0.101 0.000
H90.3 Sensorineural hearing loss, bilateral
0.897 0.103 0.000
H35.4 Peripheral retinal degeneration
0.896 0.104 0.000
M35.1 Other overlap syndromes
0.895 0.105 0.000
I63.8 Other cerebral infarction
0.895 0.105 0.000
M60 Myositis
0.891 0.109 0.000
M88 Paget's disease of bone [osteitis deformans]
0.891 0.109 0.000
I83 Varicose veins of lower extremities
0.000 0.109 0.890
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.888 0.112 0.000
K74.5 Biliary cirrhosis, unspecified
0.888 0.112 0.000
I77 Other disorders of arteries and arterioles
0.888 0.112 0.000
M34.8 Other forms of systemic sclerosis
0.884 0.116 0.000
K75.9 Inflammatory liver disease, unspecified
0.883 0.117 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.117 0.883
H61.2 Impacted cerumen
0.882 0.118 0.000
I62 Other nontraumatic intracranial haemorrhage
0.882 0.118 0.000
E78.2 Mixed hyperlipidaemia
0.882 0.118 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.879 0.121 0.000
E14.8 With unspecified complications
0.879 0.121 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.879 0.121 0.000
H30 Chorioretinal inflammation
0.878 0.122 0.000
M25 Other joint disorders, not elsewhere classified
0.876 0.124 0.000
E21.3 Hyperparathyroidism, unspecified
0.874 0.126 0.000
E14.6 With other specified complications
0.872 0.128 0.000
I77.6 Arteritis, unspecified
0.871 0.129 0.000
H60 Otitis externa
0.871 0.129 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.870 0.130 0.000
Chapter XX External causes of morbidity and mortality
0.870 0.130 0.000
J69.0 Pneumonitis due to food and vomit
0.869 0.131 0.000
M70-M79 Other soft tissue disorders
0.869 0.131 0.000
M67 Other disorders of synovium and tendon
0.868 0.132 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.865 0.135 0.000
C91.1 Chronic lymphocytic leukaemia
0.864 0.136 0.000
D50 Iron deficiency anaemia
0.862 0.138 0.000
M10.9 Gout, unspecified
0.861 0.139 0.000
E10.7 With multiple complications
0.861 0.139 0.000
M75 Shoulder lesions
0.860 0.140 0.000
D69 Purpura and other haemorrhagic conditions
0.857 0.143 0.000
E61 Deficiency of other nutrient elements
0.857 0.143 0.000
M75.0 Adhesive capsulitis of shoulder
0.857 0.143 0.000
L10-L14 Bullous disorders
0.856 0.144 0.000
M67.1 Other contracture of tendon (sheath)
0.855 0.145 0.000
H43-H45 Disorders of vitreous body and globe
0.854 0.146 0.000
M32 Systemic lupus erythematosus
0.852 0.148 0.000
E20 Hypoparathyroidism
0.852 0.148 0.000
E51 Thiamine deficiency
0.852 0.148 0.000
E78.5 Hyperlipidaemia, unspecified
0.851 0.149 0.000
E14.1 With ketoacidosis
0.850 0.150 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.850 0.150 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.849 0.151 0.000
M34.9 Systemic sclerosis, unspecified
0.849 0.151 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.847 0.153 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.843 0.157 0.000
W00-W19 Falls
0.843 0.157 0.000
E10.6 With other specified complications
0.843 0.157 0.000
E11.1 With ketoacidosis
0.843 0.157 0.000
D83 Common variable immunodeficiency
0.841 0.159 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.841 0.159 0.000
K72 Hepatic failure, not elsewhere classified
0.837 0.163 0.000
C83.7 Burkitt's tumour
0.836 0.164 0.000
H31 Other disorders of choroid
0.835 0.164 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.835 0.165 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.834 0.166 0.000
M60.9 Myositis, unspecified
0.833 0.167 0.000
H35.2 Other proliferative retinopathy
0.831 0.169 0.000
D53 Other nutritional anaemias
0.830 0.170 0.000
H65-H75 Diseases of middle ear and mastoid
0.827 0.173 0.000
C91.5 Adult T-cell leukaemia
0.826 0.174 0.000
M25.9 Joint disorder, unspecified
0.826 0.174 0.000
M88.9 Paget's disease of bone, unspecified
0.825 0.175 0.000
M34.0 Progressive systemic sclerosis
0.825 0.175 0.000
E14.2 Withrenal complications
0.825 0.175 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.824 0.175 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.824 0.176 0.000
E14.5 With peripheral circulatory complications
0.823 0.177 0.000
K74.3 Primary biliary cirrhosis
0.821 0.179 0.000
E21.4 Other specified disorders of parathyroid gland
0.821 0.179 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.819 0.181 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.817 0.183 0.000
L50-L54 Urticaria and erythema
0.816 0.184 0.000
M66 Spontaneous rupture of synovium and tendon
0.814 0.186 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.812 0.188 0.000
M12 Other specific arthropathies
0.812 0.188 0.000
C95 Leukaemia of unspecified cell type
0.812 0.188 0.000
C91.9 Lymphoid leukaemia, unspecified
0.812 0.188 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.810 0.190 0.000
E11.0 With coma
0.810 0.190 0.000
J32 Chronic sinusitis
0.810 0.190 0.000
E79 Disorders of purine and pyrimidine metabolism
0.810 0.190 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.810 0.190 0.000
D61.1 Drug-induced aplastic anaemia
0.809 0.191 0.000
E89.1 Postprocedural hypoinsulinaemia
0.809 0.191 0.000
K74.6 Other and unspecified cirrhosis of liver
0.808 0.192 0.000
G53.0 Postzoster neuralgia
0.808 0.192 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.807 0.193 0.000
H43 Disorders of vitreous body
0.806 0.194 0.000
K50-K52 Noninfective enteritis and colitis
0.805 0.195 0.000
E88 Other metabolic disorders
0.805 0.195 0.000
C81.2 Mixed cellularity
0.804 0.196 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.803 0.197 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.802 0.198 0.000
M25.0 Haemarthrosis
0.802 0.198 0.000
G56.2 Lesion of ulnar nerve
0.802 0.198 0.000
E24 Cushing's syndrome
0.801 0.199 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.800 0.200 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.800 0.200 0.000
D55-D59 Haemolytic anaemias
0.800 0.200 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.800 0.200 0.000
L13 Other bullous disorders
0.799 0.201 0.000
L40-L45 Papulosquamous disorders
0.769 0.203 0.028
H90.5 Sensorineural hearing loss, unspecified
0.797 0.203 0.000
M31 Other necrotising vasculopathies
0.796 0.204 0.000
M86.9 Osteomyelitis, unspecified
0.796 0.204 0.000
G70-G73 Diseases of myoneural junction and muscle
0.795 0.205 0.000
H30.9 Chorioretinal inflammation, unspecified
0.794 0.206 0.000
K52 Other non-infective gastro-enteritis and colitis
0.793 0.206 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.793 0.207 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.790 0.210 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.789 0.211 0.000
D61.0 Constitutional aplastic anaemia
0.789 0.211 0.000
M75.5 Bursitis of shoulder
0.788 0.212 0.000
E55 Vitamin D deficiency
0.788 0.212 0.000
D64.3 Other sideroblastic anaemias
0.787 0.213 0.000
E11.6 With other specified complications
0.786 0.213 0.000
I74 Arterial embolism and thrombosis
0.786 0.214 0.000
W20-W49 Exposure to inanimate mechanical forces
0.785 0.215 0.000
G56.8 Other mononeuropathies of upper limb
0.783 0.217 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.779 0.221 0.000
M06.8 Other specified rheumatoid arthritis
0.778 0.222 0.000
E11.7 With multiple complications
0.778 0.222 0.000
W05 Fall involving wheelchair
0.777 0.223 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.776 0.224 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.775 0.225 0.000
M14 Arthropathies in other diseases classified elsewhere
0.775 0.225 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.772 0.228 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.772 0.228 0.000
C83.1 Small cleaved cell (diffuse)
0.771 0.228 0.000
W19 Unspecified fall
0.770 0.230 0.000
H43.1 Vitreous haemorrhage
0.769 0.231 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.769 0.231 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.769 0.231 0.000
G52 Disorders of other cranial nerves
0.768 0.232 0.000
E31 Polyglandular dysfunction
0.766 0.234 0.000
M10.94 Gout, unspecified (Hand)
0.766 0.234 0.000
E78.4 Other hyperlipidaemia
0.766 0.234 0.000
J45.1 Nonallergic asthma
0.765 0.235 0.000
E74 Other disorders of carbohydrate metabolism
0.764 0.236 0.000
H92 Otalgia and effusion of ear
0.764 0.236 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.763 0.237 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.762 0.238 0.000
D84 Other immunodeficiencies
0.761 0.239 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.758 0.242 0.000
L13.0 Dermatitis herpetiformis
0.758 0.242 0.000
I70 Atherosclerosis
0.757 0.243 0.000
M08 Juvenile arthritis
0.756 0.244 0.000
M60.99 Myositis, unspecified (Site unspecified)
0.756 0.244 0.000
L20-L30 Dermatitis and eczema
0.755 0.245 0.000
M86.8 Other osteomyelitis
0.755 0.245 0.000
Chapter II Neoplasms
0.754 0.246 0.000
E51.2 Wernicke's encephalopathy
0.753 0.247 0.000
C91.4 Hairy-cell leukaemia
0.752 0.248 0.000
M10.0 Idiopathic gout
0.752 0.248 0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)
0.750 0.250 0.000
H31.0 Chorioretinal scars
0.750 0.250 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.750 0.250 0.000
M25.06 Haemarthrosis (Lower leg)
0.749 0.251 0.000
H61.3 Acquired stenosis of external ear canal
0.749 0.251 0.000
C92 Myeloid leukaemia
0.749 0.251 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.749 0.251 0.000
E20.9 Hypoparathyroidism, unspecified
0.749 0.251 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.749 0.251 0.000
M35.2 Behcet's disease
0.748 0.252 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.748 0.252 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.746 0.254 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.746 0.254 0.000
H60.1 Cellulitis of external ear
0.746 0.254 0.000
W19.9 Unspecified place
0.745 0.255 0.000
K90.8 Other intestinal malabsorption
0.745 0.255 0.000
G58 Other mononeuropathies
0.744 0.256 0.000
E61.1 Iron deficiency
0.743 0.257 0.000
G56.1 Other lesions of median nerve
0.743 0.257 0.000
K52.1 Toxic gastro-enteritis and colitis
0.742 0.258 0.000
H60.4 Cholesteatoma of external ear
0.742 0.258 0.000
M35.7 Hypermobility syndrome
0.741 0.259 0.000
G51 Facial nerve disorders
0.741 0.259 0.000
M11 Other crystal arthropathies
0.741 0.259 0.000
E78.6 Lipoprotein deficiency
0.739 0.261 0.000
C88 Malignant immunoproliferative diseases
0.738 0.262 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.738 0.262 0.000
H60.3 Other infective otitis externa
0.737 0.263 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.737 0.263 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.737 0.263 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.737 0.263 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.736 0.264 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.736 0.264 0.000
L08 Other local infections of skin and subcutaneous tissue
0.735 0.265 0.000
E06.5 Other chronic thyroiditis
0.735 0.265 0.000
E70 Disorders of aromatic amino-acid metabolism
0.734 0.266 0.000
D69.4 Other primary thrombocytopenia
0.734 0.266 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.734 0.266 0.000
L43 Lichen planus
0.725 0.267 0.007
W03 Other fall on same level due to collision with, or pushing by, another person
0.732 0.268 0.000
E21.0 Primary hyperparathyroidism
0.732 0.268 0.000
D83.9 Common variable immunodeficiency, unspecified
0.731 0.269 0.000
J60 Coalworker's pneumoconiosis
0.730 0.270 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.730 0.270 0.000
J32.8 Other chronic sinusitis
0.729 0.271 0.000
K75.0 Abscess of liver
0.729 0.271 0.000
G56.4 Causalgia
0.728 0.272 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.728 0.272 0.000
D50.1 Sideropenic dysphagia
0.727 0.272 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.727 0.273 0.000
K73.9 Chronic hepatitis, unspecified
0.727 0.273 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.727 0.273 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.726 0.274 0.000
E21.2 Other hyperparathyroidism
0.726 0.274 0.000
M22 Disorders of patella
0.725 0.275 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.724 0.276 0.000
D69.2 Other nonthrombocytopenic purpura
0.722 0.278 0.000
J62 Pneumoconiosis due to dust containing silica
0.721 0.279 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.721 0.279 0.000
D82 Immunodeficiency associated with other major defects
0.719 0.281 0.000
D69.6 Thrombocytopenia, unspecified
0.718 0.282 0.000
H90.2 Conductive hearing loss, unspecified
0.718 0.282 0.000
D53.9 Nutritional anaemia, unspecified
0.717 0.282 0.000
C81.0 Lymphocytic predominance
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
K75.2 Nonspecific reactive hepatitis
0.717 0.283 0.000
K75.1 Phlebitis of portal vein
0.717 0.283 0.000
G72 Other myopathies
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.716 0.283 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.716 0.283 0.000
E89.5 Postprocedural testicular hypofunction
0.716 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.716 0.284 0.000
C94 Other leukaemias of specified cell type
0.716 0.284 0.000
C86 Other specified types of T/NK-cell lymphoma
0.716 0.284 0.000
C85.0 Lymphosarcoma
0.716 0.284 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.716 0.284 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.715 0.285 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.715 0.285 0.000
M90 Osteopathies in diseases classified elsewhere
0.714 0.286 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.714 0.286 0.000
E32 Diseases of thymus
0.714 0.286 0.000
E30 Disorders of puberty, not elsewhere classified
0.714 0.286 0.000
E25 Adrenogenital disorders
0.714 0.286 0.000
D81 Combined immunodeficiencies
0.714 0.286 0.000
E06.4 Drug-induced thyroiditis
0.714 0.286 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.714 0.286 0.000
E06.1 Subacute thyroiditis
0.714 0.286 0.000
E06.0 Acute thyroiditis
0.714 0.286 0.000
M21 Other acquired deformities of limbs
0.714 0.286 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
K71 Toxic liver disease
0.713 0.287 0.000
X58 Exposure to other specified factors
0.713 0.287 0.000
M86.1 Other acute osteomyelitis
0.713 0.287 0.000
E40-E46 Malnutrition
0.713 0.287 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.712 0.288 0.000
M61 Calcification and ossification of muscle
0.712 0.288 0.000
J45.8 Mixed asthma
0.712 0.288 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.711 0.289 0.000
M33 Dermatopolymyositis
0.711 0.289 0.000
C81.7 Other Hodgkin's disease
0.711 0.289 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.711 0.289 0.000
C81.3 Lymphocytic depletion
0.711 0.289 0.000
D74 Methaemoglobinaemia
0.711 0.289 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.711 0.289 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.711 0.289 0.000
D61.8 Other specified aplastic anaemias
0.710 0.290 0.000
D61.3 Idiopathic aplastic anaemia
0.710 0.290 0.000
D61.2 Aplastic anaemia due to other external agents
0.710 0.290 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.710 0.290 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.710 0.290 0.000
E63 Other nutritional deficiencies
0.710 0.290 0.000
E56 Other vitamin deficiencies
0.710 0.290 0.000
E50 Vitamin A deficiency
0.710 0.290 0.000
E60 Dietary zinc deficiency
0.710 0.290 0.000
E59 Dietary selenium deficiency
0.710 0.290 0.000
E54 Ascorbic acid deficiency
0.710 0.290 0.000
E52 Niacin deficiency [pellagra]
0.710 0.290 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.708 0.292 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.708 0.292 0.000
Y52 Agents primarily affecting the cardiovascular system
0.708 0.292 0.000
C83.6 Undifferentiated (diffuse)
0.707 0.293 0.000
C83.5 Lymphoblastic (diffuse)
0.707 0.293 0.000
C83.4 Immunoblastic (diffuse)
0.707 0.293 0.000
C83.2 Mixed small and large cell (diffuse)
0.707 0.293 0.000
E27.5 Adrenomedullary hyperfunction
0.707 0.293 0.000
E27.0 Other adrenocortical overactivity
0.707 0.293 0.000
G30-G32 Other degenerative diseases of the nervous system
0.706 0.294 0.000
D50.8 Other iron deficiency anaemias
0.705 0.295 0.000
G51.9 Disorder of facial nerve, unspecified
0.705 0.295 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.705 0.295 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.704 0.296 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.704 0.296 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.703 0.297 0.000
M62.9 Disorder of muscle, unspecified
0.703 0.297 0.000
M62.4 Contracture of muscle
0.703 0.297 0.000
M62.3 Immobility syndrome (paraplegic)
0.703 0.297 0.000
M62.2 Ischaemic infarction of muscle
0.703 0.297 0.000
M06.4 Inflammatory polyarthropathy
0.702 0.298 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.702 0.298 0.000
H60.5 Acute otitis externa, non-infective
0.701 0.299 0.000
J64 Unspecified pneumoconiosis
0.701 0.299 0.000
M88.8 Paget's disease of other bones
0.701 0.299 0.000
M30 Polyarteritis nodosa and related conditions
0.701 0.299 0.000
M62.6 Muscle strain
0.700 0.300 0.000
M00-M03 Infectious arthropathies
0.700 0.300 0.000
E84 Cystic fibrosis
0.698 0.301 0.000
M62.0 Diastasis of muscle
0.698 0.302 0.000
M77 Other enthesopathies
0.698 0.302 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.698 0.302 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.697 0.303 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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