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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857128
log Bayes Factor = 28.7605
Chromosome 6   position 32,776,832  (GRCh37) Explore rs2857128 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40 Psoriasis
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E20-E35 Disorders of other endocrine glands
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
C44.6 Skin of upper limb, including shoulder
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
C44.7 Skin of lower limb, including hip
0.000 0.002 0.998
C44.3 Skin of other and unspecified parts of face
0.000 0.002 0.998
L40.9 Psoriasis, unspecified
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.007 0.993
E23 Hypofunction and other disorders of pituitary gland
0.000 0.013 0.987
L57.0 Actinic keratosis
0.000 0.020 0.980
C44.4 Skin of scalp and neck
0.000 0.022 0.978
G35-G37 Demyelinating diseases of the central nervous system
0.966 0.034 0.000
E27 Other disorders of adrenal gland
0.000 0.034 0.966
G37 Other demyelinating diseases of central nervous system
0.955 0.045 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.060 0.940
G37.9 Demyelinating disease of central nervous system, unspecified
0.934 0.066 0.000
C44.2 Skin of ear and external auricular canal
0.000 0.070 0.930
E23.6 Other disorders of pituitary gland
0.000 0.073 0.927
E27.1 Primary adrenocortical insufficiency
0.000 0.078 0.922
E10.2 With renal complications
0.000 0.083 0.917
E10.9 Without complications
0.000 0.088 0.912
E10.5 With peripheral circulatory complications
0.000 0.090 0.910
E24 Cushing's syndrome
0.000 0.108 0.892
E10.1 With ketoacidosis
0.000 0.114 0.886
E83.1 Disorders of iron metabolism
0.882 0.118 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.876 0.124 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.126 0.874
J45.9 Asthma, unspecified
0.863 0.137 0.000
L40-L45 Papulosquamous disorders
0.000 0.146 0.854
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.157 0.843
L40.1 Generalised pustular psoriasis
0.000 0.171 0.829
L40.3 Pustulosis palmaris et plantaris
0.000 0.171 0.829
E28 Ovarian dysfunction
0.000 0.172 0.828
E10.0 With coma
0.000 0.190 0.810
E23.0 Hypopituitarism
0.000 0.194 0.806
C44.0 Skin of lip
0.000 0.202 0.798
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.207 0.793
G36 Other acute disseminated demyelination
0.788 0.212 0.000
E13 Other specified diabetes mellitus
0.000 0.215 0.785
E06 Thyroiditis
0.000 0.216 0.784
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.222 0.778
E10.4 With neurological complications
0.000 0.225 0.775
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.228 0.772
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.228 0.772
L40.4 Guttate psoriasis
0.000 0.230 0.770
M07.3 Other psoriatic arthropathies
0.000 0.232 0.768
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.235 0.765
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.238 0.762
E29 Testicular dysfunction
0.000 0.249 0.751
E26 Hyperaldosteronism
0.000 0.252 0.748
L40.0 Psoriasis vulgaris
0.000 0.254 0.746
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.258 0.741
E24.0 Pituitary-dependent Cushing's disease
0.000 0.262 0.738
E24.2 Drug-induced Cushing's syndrome
0.000 0.269 0.731
L43 Lichen planus
0.000 0.271 0.729
J45 Asthma
0.726 0.274 0.000
E10.7 With multiple complications
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.284 0.716
E32 Diseases of thymus
0.000 0.284 0.716
E31 Polyglandular dysfunction
0.000 0.284 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.292 0.708
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.292 0.708
E23.1 Drug-induced hypopituitarism
0.000 0.292 0.708
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.294 0.706
E24.9 Cushing's syndrome, unspecified
0.000 0.303 0.697
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.305 0.695
E27.5 Adrenomedullary hyperfunction
0.000 0.307 0.693
E27.0 Other adrenocortical overactivity
0.000 0.307 0.693
E25 Adrenogenital disorders
0.000 0.308 0.692
E28.2 Polycystic ovarian syndrome
0.000 0.308 0.692
J45.0 Predominantly allergic asthma
0.689 0.311 0.000
G37.5 Concentric sclerosis [Balo]
0.685 0.315 0.000
G37.4 Subacute necrotising myelitis
0.685 0.315 0.000
G37.2 Central pontine myelinolysis
0.685 0.315 0.000
G37.1 Central demyelination of corpus callosum
0.685 0.315 0.000
G37.0 Diffuse sclerosis
0.685 0.315 0.000
E06.3 Autoimmune thyroiditis
0.000 0.326 0.674
E34 Other endocrine disorders
0.000 0.334 0.666
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.335 0.665
E21.3 Hyperparathyroidism, unspecified
0.000 0.335 0.665
E05.8 Other thyrotoxicosis
0.000 0.338 0.662
G36.0 Neuromyelitis optica [Devic]
0.661 0.339 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.343 0.657
E10.6 With other specified complications
0.000 0.344 0.656
E27.9 Disorder of adrenal gland, unspecified
0.000 0.344 0.656
E40-E46 Malnutrition
0.000 0.353 0.647
E11 Non-insulin-dependent diabetes mellitus
0.000 0.357 0.643
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.358 0.641
E24.8 Other Cushing's syndrome
0.000 0.360 0.640
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.360 0.640
E24.3 Ectopic ACTH syndrome
0.000 0.360 0.640
E24.1 Nelson's syndrome
0.000 0.360 0.640
E23.2 Diabetes insipidus
0.000 0.367 0.633
L57.5 Actinic granuloma
0.000 0.373 0.627
L57.3 Poikiloderma of Civatte
0.000 0.373 0.627
L57.2 Cutis rhomboidalis nuchae
0.000 0.373 0.627
L57.1 Actinic reticuloid
0.000 0.373 0.627
E13.9 Without complications
0.000 0.380 0.620
E27.8 Other specified disorders of adrenal gland
0.000 0.382 0.618
E28.3 Primary ovarian failure
0.000 0.382 0.618
L43.9 Lichen planus, unspecified
0.000 0.383 0.617
E11.3 With ophthalmic complications
0.000 0.385 0.615
L44 Other papulosquamous disorders
0.000 0.388 0.612
L41 Parapsoriasis
0.000 0.388 0.612
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.388 0.612
E20 Hypoparathyroidism
0.000 0.390 0.609
E27.2 Addisonian crisis
0.000 0.391 0.608
E22 Hyperfunction of pituitary gland
0.000 0.395 0.605
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.398 0.602
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.599 0.400 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.406 0.594
E28.8 Other ovarian dysfunction
0.000 0.406 0.594
E28.1 Androgen excess
0.000 0.406 0.594
E28.0 Oestrogen excess
0.000 0.406 0.594
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.413 0.587
E10.8 With unspecified complications
0.000 0.417 0.583
E13.3 With ophthalmic complications
0.000 0.422 0.577
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.423 0.577
E06.5 Other chronic thyroiditis
0.000 0.425 0.575
E29.1 Testicular hypofunction
0.000 0.426 0.574
E26.0 Primary hyperaldosteronism
0.000 0.432 0.568
G36.9 Acute disseminated demyelination, unspecified
0.565 0.435 0.000
G36.8 Other specified acute disseminated demyelination
0.565 0.435 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.565 0.435 0.000
L43.8 Other lichen planus
0.000 0.436 0.564
E65 Localised adiposity
0.000 0.437 0.563
E13.8 With unspecified complications
0.000 0.437 0.563
E13.7 With multiple complications
0.000 0.437 0.563
E13.6 With other specified complications
0.000 0.437 0.563
E13.5 With peripheral circulatory complications
0.000 0.437 0.563
E13.4 With neurological complications
0.000 0.437 0.563
E13.2 With renal complications
0.000 0.437 0.563
E13.1 With ketoacidosis
0.000 0.437 0.563
E13.0 With coma
0.000 0.437 0.563
E06.4 Drug-induced thyroiditis
0.000 0.438 0.562
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.438 0.562
E06.0 Acute thyroiditis
0.000 0.438 0.562
E06.9 Thyroiditis, unspecified
0.000 0.440 0.560
L55 Sunburn
0.000 0.442 0.558
E16 Other disorders of pancreatic internal secretion
0.000 0.443 0.557
J45.8 Mixed asthma
0.555 0.445 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.446 0.553
E04 Other non-toxic goitre
0.000 0.447 0.553
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.447 0.553
M07.38 Other psoriatic arthropathies (Other)
0.000 0.449 0.551
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.449 0.551
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.449 0.551
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.449 0.551
E21.2 Other hyperparathyroidism
0.000 0.450 0.550
E34.8 Other specified endocrine disorders
0.000 0.456 0.544
J45.1 Nonallergic asthma
0.542 0.458 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.461 0.539
E29.8 Other testicular dysfunction
0.000 0.461 0.539
E29.0 Testicular hyperfunction
0.000 0.461 0.539
E26.9 Hyperaldosteronism, unspecified
0.000 0.463 0.536
E26.8 Other hyperaldosteronism
0.000 0.463 0.536
E26.1 Secondary hyperaldosteronism
0.000 0.463 0.536
E15 Nondiabetic hypoglycaemic coma
0.000 0.468 0.532
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.468 0.532
L40.8 Other psoriasis
0.000 0.470 0.530
L43.3 Subacute (active) lichen planus
0.000 0.477 0.523
L43.2 Lichenoid drug reaction
0.000 0.477 0.523
L43.1 Bullous lichen planus
0.000 0.477 0.523
L43.0 Hypertrophic lichen planus
0.000 0.477 0.523
L42 Pityriasis rosea
0.000 0.482 0.517
E11.2 With renal complications
0.000 0.484 0.516
L58 Radiodermatitis
0.000 0.484 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.513
E30.8 Other disorders of puberty
0.000 0.486 0.513
E30.1 Precocious puberty
0.000 0.486 0.513
E30.0 Delayed puberty
0.000 0.486 0.513
E31.9 Polyglandular dysfunction, unspecified
0.000 0.486 0.513
E31.8 Other polyglandular dysfunction
0.000 0.486 0.513
E31.1 Polyglandular hyperfunction
0.000 0.486 0.513
E31.0 Autoimmune polyglandular failure
0.000 0.486 0.513
E32.9 Disease of thymus, unspecified
0.000 0.486 0.513
E32.8 Other diseases of thymus
0.000 0.486 0.513
E32.1 Abscess of thymus
0.000 0.486 0.513
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.513
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.513
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.513
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E11.0 With coma
0.000 0.490 0.510
E25.9 Adrenogenital disorder, unspecified
0.000 0.503 0.496
E25.8 Other adrenogenital disorders
0.000 0.503 0.496
E04.0 Non-toxic diffuse goitre
0.000 0.505 0.495
L10-L14 Bullous disorders
0.000 0.511 0.489
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.513 0.487
L57.4 Cutis laxa senilis
0.000 0.516 0.484
E34.5 Androgen resistance syndrome
0.000 0.522 0.477
E34.4 Constitutional tall stature
0.000 0.522 0.477
E34.3 Short stature, not elsewhere classified
0.000 0.522 0.477
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.522 0.477
E34.1 Other hypersecretion of intestinal hormones
0.000 0.522 0.477
E70-E90 Metabolic disorders
0.000 0.523 0.477
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.527 0.473
E67 Other hyperalimentation
0.000 0.529 0.471
E68 Sequelae of hyperalimentation
0.000 0.529 0.471
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.533 0.467
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.536 0.464
E45 Retarded development following protein-energy malnutrition
0.000 0.536 0.464
E43 Unspecified severe protein-energy malnutrition
0.000 0.536 0.464
E42 Marasmic kwashiorkor
0.000 0.536 0.464
E41 Nutritional marasmus
0.000 0.536 0.464
E40 Kwashiorkor
0.000 0.536 0.464
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.536 0.463
E11.7 With multiple complications
0.000 0.539 0.461
E06.1 Subacute thyroiditis
0.000 0.542 0.458
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.545 0.455
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.550 0.450
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.553 0.447
E11.6 With other specified complications
0.000 0.556 0.444
E11.8 With unspecified complications
0.000 0.557 0.443
E07 Other disorders of thyroid
0.000 0.558 0.442
L41.9 Parapsoriasis, unspecified
0.000 0.561 0.439
L41.8 Other parapsoriasis
0.000 0.561 0.439
L41.5 Retiform parapsoriasis
0.000 0.561 0.439
L41.4 Large plaque parapsoriasis
0.000 0.561 0.439
L41.3 Small plaque parapsoriasis
0.000 0.561 0.439
L41.2 Lymphomatoid papulosis
0.000 0.561 0.439
L41.1 Pityriasis lichenoides chronica
0.000 0.561 0.439
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.561 0.439
L44.9 Papulosquamous disorder, unspecified
0.000 0.561 0.439
L44.8 Other specified papulosquamous disorders
0.000 0.561 0.439
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.561 0.439
L44.3 Lichen ruber moniliformis
0.000 0.561 0.439
L44.2 Lichen striatus
0.000 0.561 0.439
L44.1 Lichen nitidus
0.000 0.561 0.439
L44.0 Pityriasis rubra pilaris
0.000 0.561 0.439
E20.1 Pseudohypoparathyroidism
0.000 0.563 0.437
E20.0 Idiopathic hypoparathyroidism
0.000 0.563 0.437
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.565 0.435
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.566 0.433
E22.8 Other hyperfunction of pituitary gland
0.000 0.566 0.433
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.567 0.433
E89.0 Postprocedural hypothyroidism
0.000 0.567 0.433
L56.3 Solar urticaria
0.000 0.568 0.431
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.568 0.431
L56.1 Drug photoallergic response
0.000 0.568 0.431
L56.0 Drug phototoxic response
0.000 0.568 0.431
E22.1 Hyperprolactinaemia
0.000 0.570 0.430
E34.9 Endocrine disorder, unspecified
0.000 0.573 0.426
E21.0 Primary hyperparathyroidism
0.000 0.579 0.421
E20.9 Hypoparathyroidism, unspecified
0.000 0.592 0.407
E16.2 Hypoglycaemia, unspecified
0.000 0.595 0.405
E78.2 Mixed hyperlipidaemia
0.000 0.597 0.403
L55.9 Sunburn, unspecified
0.000 0.600 0.400
L55.8 Other sunburn
0.000 0.600 0.400
L55.2 Sunburn of third degree
0.000 0.600 0.400
L55.1 Sunburn of second degree
0.000 0.600 0.400
L55.0 Sunburn of first degree
0.000 0.600 0.400
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.601 0.399
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.601 0.399
E16.4 Abnormal secretion of gastrin
0.000 0.601 0.399
E16.3 Increased secretion of glucagon
0.000 0.601 0.399
E04.8 Other specified non-toxic goitre
0.000 0.603 0.397
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.603 0.397
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.603 0.397
E88 Other metabolic disorders
0.000 0.603 0.397
E46 Unspecified protein-energy malnutrition
0.000 0.605 0.395
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.608 0.392
L56.4 Polymorphous light eruption
0.000 0.610 0.389
C44.9 Malignant neoplasm of skin, unspecified
0.001 0.615 0.385
E16.1 Other hypoglycaemia
0.000 0.619 0.381
E78.6 Lipoprotein deficiency
0.000 0.624 0.376
E34.0 Carcinoid syndrome
0.000 0.624 0.375
E04.2 Non-toxic multinodular goitre
0.000 0.625 0.375
E20.8 Other hypoparathyroidism
0.000 0.629 0.371
E78.5 Hyperlipidaemia, unspecified
0.000 0.629 0.371
L58.1 Chronic radiodermatitis
0.000 0.630 0.370
L58.0 Acute radiodermatitis
0.000 0.630 0.370
E11.5 With peripheral circulatory complications
0.000 0.632 0.368
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.633 0.367
L12 Pemphigoid
0.000 0.636 0.364
E89.3 Postprocedural hypopituitarism
0.000 0.639 0.361
E79 Disorders of purine and pyrimidine metabolism
0.000 0.639 0.360
E78.1 Pure hyperglyceridaemia
0.000 0.643 0.357
L10 Pemphigus
0.000 0.649 0.351
L14 Bullous disorders in diseases classified elsewhere
0.000 0.649 0.351
E84 Cystic fibrosis
0.000 0.650 0.349
L11 Other acantholytic disorders
0.000 0.653 0.347
E11.1 With ketoacidosis
0.000 0.656 0.344
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.656 0.344
E77 Disorders of glycoprotein metabolism
0.000 0.658 0.342
E76 Disorders of glycosaminoglycan metabolism
0.000 0.658 0.342
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.658 0.342
E70 Disorders of aromatic amino-acid metabolism
0.000 0.658 0.342
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.658 0.342
E67.8 Other specified hyperalimentation
0.000 0.662 0.338
E67.3 Hypervitaminosis D
0.000 0.662 0.338
E67.2 Megavitamin-B6 syndrome
0.000 0.662 0.338
E67.1 Hypercarotenaemia
0.000 0.662 0.338
E67.0 Hypervitaminosis A
0.000 0.662 0.338
E44.1 Mild protein-energy malnutrition
0.000 0.667 0.333
E44.0 Moderate protein-energy malnutrition
0.000 0.667 0.333
E88.3 Tumour lysis syndrome
0.000 0.670 0.330
C44.5 Skin of trunk
0.000 0.672 0.328
L58.9 Radiodermatitis, unspecified
0.000 0.673 0.327
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.673 0.326
E88.8 Other specified metabolic disorders
0.000 0.674 0.326
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.674 0.326
E89.5 Postprocedural testicular hypofunction
0.000 0.674 0.326
E89.4 Postprocedural ovarian failure
0.000 0.674 0.326
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.676 0.324
E50-E64 Other nutritional deficiencies
0.000 0.678 0.322
L13 Other bullous disorders
0.000 0.679 0.321
E07.1 Dyshormogenetic goitre
0.000 0.683 0.317
E07.0 Hypersecretion of calcitonin
0.000 0.683 0.317
L60-L75 Disorders of skin appendages
0.000 0.684 0.316
E04.9 Non-toxic goitre, unspecified
0.000 0.693 0.307
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.693 0.307
E22.0 Acromegaly and pituitary gigantism
0.000 0.695 0.304
E89.1 Postprocedural hypoinsulinaemia
0.000 0.696 0.304
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.697 0.303
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.698 0.302
E88.2 Lipomatosis, not elsewhere classified
0.000 0.698 0.302
E89.2 Postprocedural hypoparathyroidism
0.000 0.705 0.295
E72 Other disorders of amino-acid metabolism
0.000 0.707 0.292
M07 Psoriatic and enteropathic arthropathies
0.000 0.709 0.291
E74 Other disorders of carbohydrate metabolism
0.000 0.715 0.285
E73 Lactose intolerance
0.000 0.715 0.284
E07.8 Other specified disorders of thyroid
0.000 0.717 0.283
E78.4 Other hyperlipidaemia
0.000 0.717 0.283
E85 Amyloidosis
0.000 0.717 0.283
E80.4 Gilbert's syndrome
0.000 0.718 0.282
E03 Other hypothyroidism
0.000 0.721 0.279
L12.9 Pemphigoid, unspecified
0.000 0.722 0.278
E78.3 Hyperchylomicronaemia
0.000 0.722 0.278
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.723 0.277
L71 Rosacea
0.000 0.723 0.277
E88.9 Metabolic disorder, unspecified
0.000 0.725 0.275
L12.8 Other pemphigoid
0.000 0.739 0.261
L12.3 Acquired epidermolysis bullosa
0.000 0.739 0.261
L12.2 Chronic bullous disease of childhood
0.000 0.739 0.261
L12.1 Cicatricial pemphigoid
0.000 0.740 0.260
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.741 0.259
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.741 0.259
E79.1 Lesch-Nyhan syndrome
0.000 0.741 0.259
E84.9 Cystic fibrosis, unspecified
0.000 0.742 0.258
E80.6 Other disorders of bilirubin metabolism
0.000 0.742 0.258
L12.0 Bullous pemphigoid
0.000 0.742 0.258
E51 Thiamine deficiency
0.000 0.743 0.257
L10.9 Pemphigus, unspecified
0.000 0.748 0.252
L10.8 Other pemphigus
0.000 0.748 0.252
L10.5 Drug-induced pemphigus
0.000 0.748 0.252
L10.4 Pemphigus erythematosus
0.000 0.748 0.252
L10.3 Brazilian pemphigus [fogo selvagem]
0.000 0.748 0.252
L10.2 Pemphigus foliaceus
0.000 0.748 0.252
L10.1 Pemphigus vegetans
0.000 0.748 0.252
L10.0 Pemphigus vulgaris
0.000 0.748 0.252
L68 Hypertrichosis
0.000 0.749 0.251
E78.8 Other disorders of lipoprotein metabolism
0.000 0.749 0.251
E84.8 Cystic fibrosis with other manifestations
0.000 0.749 0.251
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.749 0.251
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.749 0.251
L11.0 Acquired keratosis follicularis
0.000 0.750 0.250
L11.9 Acantholytic disorder, unspecified
0.000 0.751 0.249
L11.8 Other specified acantholytic disorders
0.000 0.751 0.249
L50-L54 Urticaria and erythema
0.000 0.752 0.248
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.753 0.247
E80.5 Crigler-Najjar syndrome
0.000 0.753 0.247
E80.3 Defects of catalase and peroxydase
0.000 0.753 0.247
E80.0 Hereditary erythropoietic porphyria
0.000 0.753 0.247
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.755 0.245
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.755 0.245
E70.3 Albinism
0.000 0.755 0.245
E70.2 Disorders of tyrosine metabolism
0.000 0.755 0.245
E70.1 Other hyperphenylalaninaemias
0.000 0.755 0.245
E70.0 Classical phenylketonuria
0.000 0.755 0.245
E71.3 Disorders of fatty-acid metabolism
0.000 0.755 0.245
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.755 0.245
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.755 0.245
E71.0 Maple-syrup-urine disease
0.000 0.755 0.245
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.755 0.245
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.755 0.245
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.755 0.245
E76.2 Other mucopolysaccharidoses
0.000 0.755 0.245
E76.1 Mucopolysaccharidosis, type II
0.000 0.755 0.245
E76.0 Mucopolysaccharidosis, type I
0.000 0.755 0.245
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.755 0.245
E77.8 Other disorders of glycoprotein metabolism
0.000 0.755 0.245
E77.1 Defects in glycoprotein degradation
0.000 0.755 0.245
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.755 0.245
L11.1 Transient acantholytic dermatosis [Grover]
0.000 0.757 0.243
E56 Other vitamin deficiencies
0.000 0.758 0.242
L71.9 Rosacea, unspecified
0.000 0.759 0.241
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.760 0.240
E75.6 Lipid storage disorder, unspecified
0.000 0.766 0.234
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.766 0.234
E75.3 Sphingolipidosis, unspecified
0.000 0.766 0.234
E75.1 Other gangliosidosis
0.000 0.766 0.234
E75.0 GM2 gangliosidosis
0.000 0.766 0.234
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.769 0.231
E50 Vitamin A deficiency
0.000 0.769 0.231
E60 Dietary zinc deficiency
0.000 0.769 0.231
E59 Dietary selenium deficiency
0.000 0.769 0.231
E52 Niacin deficiency [pellagra]
0.000 0.769 0.231
E80.1 Porphyria cutanea tarda
0.000 0.769 0.231
L13.9 Bullous disorder, unspecified
0.000 0.769 0.230
L13.8 Other specified bullous disorders
0.000 0.769 0.230
L13.1 Subcorneal pustular dermatitis
0.000 0.769 0.230
L63 Alopecia areata
0.000 0.769 0.231
E75.2 Other sphingolipidosis
0.000 0.770 0.229
L75 Apocrine sweat disorders
0.000 0.773 0.227
L74 Eccrine sweat disorders
0.000 0.773 0.227
L67 Hair colour and hair shaft abnormalities
0.000 0.773 0.227
L64 Androgenic alopecia
0.000 0.773 0.227
L62 Nail disorders in diseases classified elsewhere
0.000 0.773 0.227
E83 Disorders of mineral metabolism
0.089 0.773 0.138
E75.5 Other lipid storage disorders
0.000 0.775 0.224
L60 Nail disorders
0.000 0.780 0.220
E63 Other nutritional deficiencies
0.000 0.780 0.220
L71.1 Rhinophyma
0.000 0.785 0.215
E85.4 Organ-limited amyloidosis
0.000 0.786 0.214
E55 Vitamin D deficiency
0.000 0.786 0.214
E11.4 With neurological complications
0.000 0.787 0.213
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.790 0.210
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.790 0.210
E72.5 Disorders of glycine metabolism
0.000 0.790 0.210
E72.4 Disorders of ornithine metabolism
0.000 0.790 0.210
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.790 0.210
E72.2 Disorders of urea cycle metabolism
0.000 0.790 0.210
E51.2 Wernicke's encephalopathy
0.000 0.790 0.210
L70 Acne
0.000 0.791 0.209
M07.5 Arthropathy in ulcerative colitis
0.000 0.791 0.209
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.791 0.209
M07.2 Psoriatic spondylitis
0.000 0.791 0.209
M07.1 Arthritis mutilans
0.000 0.791 0.209
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.791 0.209
E54 Ascorbic acid deficiency
0.000 0.792 0.208
L60.9 Nail disorder, unspecified
0.000 0.793 0.207
E72.0 Disorders of amino-acid transport
0.000 0.794 0.206
L65 Other nonscarring hair loss
0.000 0.794 0.206
L68.0 Hirsutism
0.000 0.795 0.205
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.795 0.204
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.795 0.204
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.795 0.204
E74.2 Disorders of galactose metabolism
0.000 0.795 0.204
E74.1 Disorders of fructose metabolism
0.000 0.795 0.204
L51 Erythema multiforme
0.000 0.795 0.204
E73.8 Other lactose intolerance
0.000 0.796 0.204
E73.1 Secondary lactase deficiency
0.000 0.796 0.204
E73.0 Congenital lactase deficiency
0.000 0.796 0.204
E85.9 Amyloidosis, unspecified
0.000 0.797 0.203
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.797 0.203
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.797 0.203
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.797 0.203
E74.0 Glycogen storage disease
0.000 0.798 0.202
E58 Dietary calcium deficiency
0.000 0.798 0.202
L13.0 Dermatitis herpetiformis
0.000 0.799 0.201
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.800 0.200
E03.5 Myxoedema coma
0.000 0.800 0.200
E03.4 Atrophy of thyroid (acquired)
0.000 0.800 0.200
E03.3 Postinfectious hypothyroidism
0.000 0.800 0.200
L71.8 Other rosacea
0.000 0.801 0.198
L71.0 Perioral dermatitis
0.000 0.801 0.198
E80.2 Other porphyria
0.000 0.803 0.197
E03.1 Congenital hypothyroidism without goitre
0.000 0.805 0.195
M07.6 Other enteropathic arthropathies
0.000 0.806 0.193
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.807 0.192
E03.8 Other specified hypothyroidism
0.000 0.811 0.189
L66.9 Cicatricial alopecia, unspecified
0.000 0.814 0.186

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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