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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857130
log Bayes Factor = 28.506
Chromosome 6   position 32,776,414  (GRCh37) Explore rs2857130 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40 Psoriasis
0.000 0.001 0.999
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
C44.6 Skin of upper limb, including shoulder
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
E10-E14 Diabetes mellitus
0.000 0.002 0.998
C44.3 Skin of other and unspecified parts of face
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.002 0.998
E20-E35 Disorders of other endocrine glands
0.000 0.003 0.997
L40.9 Psoriasis, unspecified
0.000 0.003 0.997
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.003 0.997
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
E05.9 Thyrotoxicosis, unspecified
0.000 0.007 0.993
L57.0 Actinic keratosis
0.000 0.008 0.992
E23 Hypofunction and other disorders of pituitary gland
0.000 0.013 0.987
C44.4 Skin of scalp and neck
0.000 0.025 0.975
G35-G37 Demyelinating diseases of the central nervous system
0.971 0.029 0.000
E27 Other disorders of adrenal gland
0.000 0.038 0.962
C44.2 Skin of ear and external auricular canal
0.000 0.039 0.961
G37 Other demyelinating diseases of central nervous system
0.961 0.039 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.941 0.059 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.059 0.941
J45.9 Asthma, unspecified
0.940 0.060 0.000
E10.9 Without complications
0.000 0.072 0.928
E23.6 Other disorders of pituitary gland
0.000 0.074 0.926
E10.2 With renal complications
0.000 0.078 0.922
E27.1 Primary adrenocortical insufficiency
0.000 0.087 0.913
E10.1 With ketoacidosis
0.000 0.110 0.890
E24 Cushing's syndrome
0.000 0.112 0.888
E10.5 With peripheral circulatory complications
0.000 0.115 0.885
G37.8 Other specified demyelinating diseases of central nervous system
0.882 0.118 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.141 0.859
L40-L45 Papulosquamous disorders
0.000 0.144 0.856
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.166 0.834
L40.1 Generalised pustular psoriasis
0.000 0.172 0.828
L40.3 Pustulosis palmaris et plantaris
0.000 0.172 0.828
J45 Asthma
0.823 0.177 0.000
E28 Ovarian dysfunction
0.000 0.178 0.821
E23.0 Hypopituitarism
0.000 0.184 0.816
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.205 0.795
G36 Other acute disseminated demyelination
0.793 0.207 0.000
J45.0 Predominantly allergic asthma
0.791 0.209 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.215 0.785
E13 Other specified diabetes mellitus
0.000 0.217 0.783
C44.0 Skin of lip
0.000 0.219 0.781
E10.0 With coma
0.000 0.223 0.777
L40.0 Psoriasis vulgaris
0.000 0.224 0.776
L40.4 Guttate psoriasis
0.000 0.230 0.770
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.234 0.766
E10.4 With neurological complications
0.000 0.238 0.762
M07.3 Other psoriatic arthropathies
0.000 0.239 0.761
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.243 0.757
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.246 0.754
L43 Lichen planus
0.000 0.256 0.744
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.261 0.739
E24.0 Pituitary-dependent Cushing's disease
0.000 0.266 0.734
E26 Hyperaldosteronism
0.000 0.266 0.734
E06 Thyroiditis
0.000 0.272 0.728
E24.2 Drug-induced Cushing's syndrome
0.000 0.274 0.726
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.278 0.722
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.716
E10.7 With multiple complications
0.000 0.283 0.716
E29 Testicular dysfunction
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.285 0.715
E32 Diseases of thymus
0.000 0.285 0.715
E31 Polyglandular dysfunction
0.000 0.285 0.715
E30 Disorders of puberty, not elsewhere classified
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.293 0.707
E23.1 Drug-induced hypopituitarism
0.000 0.293 0.707
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.301 0.699
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.304 0.696
E21.3 Hyperparathyroidism, unspecified
0.000 0.309 0.691
E24.9 Cushing's syndrome, unspecified
0.000 0.309 0.691
E27.5 Adrenomedullary hyperfunction
0.000 0.310 0.690
E27.0 Other adrenocortical overactivity
0.000 0.310 0.690
G37.5 Concentric sclerosis [Balo]
0.689 0.311 0.000
G37.4 Subacute necrotising myelitis
0.689 0.311 0.000
G37.2 Central pontine myelinolysis
0.689 0.311 0.000
G37.1 Central demyelination of corpus callosum
0.689 0.311 0.000
G37.0 Diffuse sclerosis
0.689 0.311 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.312 0.688
E28.2 Polycystic ovarian syndrome
0.000 0.318 0.682
E27.9 Disorder of adrenal gland, unspecified
0.000 0.323 0.677
E25 Adrenogenital disorders
0.000 0.329 0.671
E40-E46 Malnutrition
0.000 0.332 0.668
G36.0 Neuromyelitis optica [Devic]
0.665 0.335 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.337 0.663
E05.8 Other thyrotoxicosis
0.000 0.340 0.660
E34 Other endocrine disorders
0.000 0.340 0.660
L43.9 Lichen planus, unspecified
0.000 0.355 0.645
E65-E68 Obesity and other hyperalimentation
0.000 0.361 0.639
E24.8 Other Cushing's syndrome
0.000 0.363 0.637
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.363 0.637
E24.3 Ectopic ACTH syndrome
0.000 0.363 0.637
E24.1 Nelson's syndrome
0.000 0.363 0.637
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.365 0.635
E10.6 With other specified complications
0.000 0.368 0.632
J45.8 Mixed asthma
0.630 0.370 0.000
E23.2 Diabetes insipidus
0.000 0.372 0.628
E10.8 With unspecified complications
0.000 0.381 0.619
E13.9 Without complications
0.000 0.382 0.618
L57.5 Actinic granuloma
0.000 0.384 0.616
L57.3 Poikiloderma of Civatte
0.000 0.384 0.616
L57.2 Cutis rhomboidalis nuchae
0.000 0.384 0.616
L57.1 Actinic reticuloid
0.000 0.384 0.616
J45.1 Nonallergic asthma
0.614 0.385 0.000
L44 Other papulosquamous disorders
0.000 0.386 0.614
L41 Parapsoriasis
0.000 0.386 0.614
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.386 0.614
E06.3 Autoimmune thyroiditis
0.000 0.388 0.612
E27.8 Other specified disorders of adrenal gland
0.000 0.388 0.611
E28.3 Primary ovarian failure
0.000 0.389 0.611
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.608 0.392 0.000
E27.2 Addisonian crisis
0.000 0.396 0.604
E04 Other non-toxic goitre
0.000 0.397 0.603
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.405 0.595
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.410 0.590
E83.1 Disorders of iron metabolism
0.589 0.410 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.411 0.589
E28.8 Other ovarian dysfunction
0.000 0.411 0.589
E28.1 Androgen excess
0.000 0.411 0.589
E28.0 Oestrogen excess
0.000 0.411 0.589
E20 Hypoparathyroidism
0.000 0.414 0.586
E13.3 With ophthalmic complications
0.000 0.424 0.576
L43.8 Other lichen planus
0.000 0.425 0.575
E22 Hyperfunction of pituitary gland
0.000 0.429 0.571
G36.9 Acute disseminated demyelination, unspecified
0.568 0.431 0.000
G36.8 Other specified acute disseminated demyelination
0.568 0.431 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.568 0.431 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.434 0.566
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.434 0.565
E21.4 Other specified disorders of parathyroid gland
0.000 0.437 0.563
E13.8 With unspecified complications
0.000 0.438 0.561
E13.7 With multiple complications
0.000 0.438 0.561
E13.6 With other specified complications
0.000 0.438 0.561
E13.5 With peripheral circulatory complications
0.000 0.438 0.561
E13.4 With neurological complications
0.000 0.438 0.561
E13.2 With renal complications
0.000 0.438 0.561
E13.1 With ketoacidosis
0.000 0.438 0.561
E13.0 With coma
0.000 0.438 0.561
E21.2 Other hyperparathyroidism
0.000 0.441 0.558
L55 Sunburn
0.000 0.451 0.549
M07.38 Other psoriatic arthropathies (Other)
0.000 0.454 0.546
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.454 0.546
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.454 0.546
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.454 0.546
E26.0 Primary hyperaldosteronism
0.000 0.456 0.544
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.456 0.544
E65 Localised adiposity
0.000 0.459 0.541
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.460 0.540
E04.0 Non-toxic diffuse goitre
0.000 0.461 0.539
E34.8 Other specified endocrine disorders
0.000 0.462 0.538
L43.3 Subacute (active) lichen planus
0.000 0.466 0.534
L43.2 Lichenoid drug reaction
0.000 0.466 0.534
L43.1 Bullous lichen planus
0.000 0.466 0.534
L43.0 Hypertrophic lichen planus
0.000 0.466 0.534
E06.5 Other chronic thyroiditis
0.000 0.467 0.533
E11.3 With ophthalmic complications
0.000 0.470 0.530
E26.9 Hyperaldosteronism, unspecified
0.000 0.474 0.526
E26.8 Other hyperaldosteronism
0.000 0.474 0.526
E26.1 Secondary hyperaldosteronism
0.000 0.474 0.526
E16 Other disorders of pancreatic internal secretion
0.000 0.476 0.524
E06.4 Drug-induced thyroiditis
0.000 0.478 0.522
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.478 0.522
E06.0 Acute thyroiditis
0.000 0.478 0.522
L58 Radiodermatitis
0.000 0.482 0.518
E15 Nondiabetic hypoglycaemic coma
0.000 0.482 0.518
L42 Pityriasis rosea
0.000 0.483 0.517
E29.1 Testicular hypofunction
0.000 0.485 0.515
E29.9 Testicular dysfunction, unspecified
0.000 0.486 0.514
E29.8 Other testicular dysfunction
0.000 0.486 0.514
E29.0 Testicular hyperfunction
0.000 0.486 0.514
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E30.9 Disorder of puberty, unspecified
0.000 0.487 0.513
E30.8 Other disorders of puberty
0.000 0.487 0.513
E30.1 Precocious puberty
0.000 0.487 0.513
E30.0 Delayed puberty
0.000 0.487 0.513
E31.9 Polyglandular dysfunction, unspecified
0.000 0.487 0.513
E31.8 Other polyglandular dysfunction
0.000 0.487 0.513
E31.1 Polyglandular hyperfunction
0.000 0.487 0.513
E31.0 Autoimmune polyglandular failure
0.000 0.487 0.513
E32.9 Disease of thymus, unspecified
0.000 0.487 0.513
E32.8 Other diseases of thymus
0.000 0.487 0.513
E32.1 Abscess of thymus
0.000 0.487 0.513
E32.0 Persistent hyperplasia of thymus
0.000 0.487 0.513
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.487 0.513
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.487 0.513
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.512
E06.9 Thyroiditis, unspecified
0.000 0.498 0.502
L40.8 Other psoriasis
0.000 0.502 0.498
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.515 0.485
E25.9 Adrenogenital disorder, unspecified
0.000 0.518 0.481
E25.8 Other adrenogenital disorders
0.000 0.518 0.481
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.521 0.479
E45 Retarded development following protein-energy malnutrition
0.000 0.521 0.479
E43 Unspecified severe protein-energy malnutrition
0.000 0.521 0.479
E42 Marasmic kwashiorkor
0.000 0.521 0.479
E41 Nutritional marasmus
0.000 0.521 0.479
E40 Kwashiorkor
0.000 0.521 0.479
L10-L14 Bullous disorders
0.000 0.522 0.478
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.523 0.477
E34.5 Androgen resistance syndrome
0.000 0.527 0.473
E34.4 Constitutional tall stature
0.000 0.527 0.473
E34.3 Short stature, not elsewhere classified
0.000 0.527 0.473
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.527 0.473
E34.1 Other hypersecretion of intestinal hormones
0.000 0.527 0.473
E11.2 With renal complications
0.000 0.536 0.464
E67 Other hyperalimentation
0.000 0.541 0.458
E68 Sequelae of hyperalimentation
0.000 0.541 0.458
E07 Other disorders of thyroid
0.000 0.544 0.456
E11.0 With coma
0.000 0.553 0.447
L57.4 Cutis laxa senilis
0.000 0.559 0.441
L41.9 Parapsoriasis, unspecified
0.000 0.560 0.440
L41.8 Other parapsoriasis
0.000 0.560 0.440
L41.5 Retiform parapsoriasis
0.000 0.560 0.440
L41.4 Large plaque parapsoriasis
0.000 0.560 0.440
L41.3 Small plaque parapsoriasis
0.000 0.560 0.440
L41.2 Lymphomatoid papulosis
0.000 0.560 0.440
L41.1 Pityriasis lichenoides chronica
0.000 0.560 0.440
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.560 0.440
L44.9 Papulosquamous disorder, unspecified
0.000 0.560 0.440
L44.8 Other specified papulosquamous disorders
0.000 0.560 0.440
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.560 0.440
L44.3 Lichen ruber moniliformis
0.000 0.560 0.440
L44.2 Lichen striatus
0.000 0.560 0.440
L44.1 Lichen nitidus
0.000 0.560 0.440
L44.0 Pityriasis rubra pilaris
0.000 0.560 0.440
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.560 0.440
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.561 0.438
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.562 0.437
E04.8 Other specified non-toxic goitre
0.000 0.567 0.433
E46 Unspecified protein-energy malnutrition
0.000 0.569 0.431
E04.2 Non-toxic multinodular goitre
0.000 0.571 0.429
L56.3 Solar urticaria
0.000 0.577 0.423
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.577 0.423
L56.1 Drug photoallergic response
0.000 0.577 0.423
L56.0 Drug phototoxic response
0.000 0.577 0.423
E20.1 Pseudohypoparathyroidism
0.000 0.580 0.420
E20.0 Idiopathic hypoparathyroidism
0.000 0.580 0.420
E34.9 Endocrine disorder, unspecified
0.000 0.580 0.420
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.585 0.415
E70-E90 Metabolic disorders
0.000 0.586 0.414
E21.0 Primary hyperparathyroidism
0.000 0.588 0.412
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.591 0.409
E22.8 Other hyperfunction of pituitary gland
0.000 0.591 0.409
E22.1 Hyperprolactinaemia
0.000 0.592 0.408
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.593 0.407
E11.7 With multiple complications
0.000 0.594 0.406
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.601 0.399
E06.1 Subacute thyroiditis
0.000 0.603 0.396
L55.9 Sunburn, unspecified
0.000 0.606 0.394
L55.8 Other sunburn
0.000 0.606 0.394
L55.2 Sunburn of third degree
0.000 0.606 0.394
L55.1 Sunburn of second degree
0.000 0.606 0.394
L55.0 Sunburn of first degree
0.000 0.606 0.394
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.608 0.392
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.610 0.390
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.610 0.390
E11.6 With other specified complications
0.000 0.611 0.389
E11.8 With unspecified complications
0.000 0.612 0.388
C44.9 Malignant neoplasm of skin, unspecified
0.001 0.613 0.387
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.615 0.384
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.618 0.382
L56.4 Polymorphous light eruption
0.000 0.618 0.382
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.624 0.376
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.624 0.376
E16.4 Abnormal secretion of gastrin
0.000 0.624 0.376
E16.3 Increased secretion of glucagon
0.000 0.624 0.376
E20.9 Hypoparathyroidism, unspecified
0.000 0.627 0.372
L58.1 Chronic radiodermatitis
0.000 0.628 0.371
L58.0 Acute radiodermatitis
0.000 0.628 0.371
E34.0 Carcinoid syndrome
0.000 0.629 0.370
E04.9 Non-toxic goitre, unspecified
0.000 0.632 0.368
E89.0 Postprocedural hypothyroidism
0.000 0.632 0.368
C44.5 Skin of trunk
0.000 0.635 0.365
E16.2 Hypoglycaemia, unspecified
0.000 0.636 0.364
E16.1 Other hypoglycaemia
0.000 0.642 0.358
E20.8 Other hypoparathyroidism
0.000 0.643 0.356
L12 Pemphigoid
0.000 0.645 0.355
E78.2 Mixed hyperlipidaemia
0.000 0.650 0.350
E88 Other metabolic disorders
0.000 0.652 0.348
E44.1 Mild protein-energy malnutrition
0.000 0.656 0.343
E44.0 Moderate protein-energy malnutrition
0.000 0.656 0.343
L10 Pemphigus
0.000 0.657 0.343
L14 Bullous disorders in diseases classified elsewhere
0.000 0.657 0.343
L58.9 Radiodermatitis, unspecified
0.000 0.659 0.340
L11 Other acantholytic disorders
0.000 0.662 0.338
E78.6 Lipoprotein deficiency
0.000 0.665 0.335
E78.5 Hyperlipidaemia, unspecified
0.000 0.665 0.335
E11.5 With peripheral circulatory complications
0.000 0.670 0.330
E67.8 Other specified hyperalimentation
0.000 0.671 0.329
E67.3 Hypervitaminosis D
0.000 0.671 0.329
E67.2 Megavitamin-B6 syndrome
0.000 0.671 0.329
E67.1 Hypercarotenaemia
0.000 0.671 0.329
E67.0 Hypervitaminosis A
0.000 0.671 0.329
E07.1 Dyshormogenetic goitre
0.000 0.673 0.327
E07.0 Hypersecretion of calcitonin
0.000 0.673 0.327
E79 Disorders of purine and pyrimidine metabolism
0.000 0.678 0.322
E89.3 Postprocedural hypopituitarism
0.000 0.681 0.319
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.684 0.315
L13 Other bullous disorders
0.000 0.686 0.314
E78.1 Pure hyperglyceridaemia
0.000 0.688 0.312
E50-E64 Other nutritional deficiencies
0.000 0.693 0.307
E11.1 With ketoacidosis
0.000 0.696 0.304
E84 Cystic fibrosis
0.000 0.696 0.303
E77 Disorders of glycoprotein metabolism
0.000 0.703 0.297
E76 Disorders of glycosaminoglycan metabolism
0.000 0.703 0.297
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.703 0.297
E70 Disorders of aromatic amino-acid metabolism
0.000 0.703 0.297
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.703 0.297
E88.3 Tumour lysis syndrome
0.000 0.711 0.289
M07 Psoriatic and enteropathic arthropathies
0.000 0.711 0.289
C43 Malignant melanoma of skin
0.000 0.712 0.288
E88.8 Other specified metabolic disorders
0.000 0.714 0.286
E22.0 Acromegaly and pituitary gigantism
0.000 0.715 0.284
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.716 0.283
L60-L75 Disorders of skin appendages
0.000 0.717 0.283
E07.8 Other specified disorders of thyroid
0.000 0.718 0.281
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.719 0.281
E89.5 Postprocedural testicular hypofunction
0.000 0.719 0.281
E89.4 Postprocedural ovarian failure
0.000 0.720 0.280
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.721 0.279
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.723 0.277
E03 Other hypothyroidism
0.000 0.726 0.274
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.726 0.274
L12.9 Pemphigoid, unspecified
0.000 0.729 0.271
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.735 0.265
E88.2 Lipomatosis, not elsewhere classified
0.000 0.736 0.264
E89.1 Postprocedural hypoinsulinaemia
0.000 0.738 0.261
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.744 0.255
L12.8 Other pemphigoid
0.000 0.745 0.255
L12.3 Acquired epidermolysis bullosa
0.000 0.745 0.255
L12.2 Chronic bullous disease of childhood
0.000 0.745 0.255
E72 Other disorders of amino-acid metabolism
0.000 0.746 0.254
L12.1 Cicatricial pemphigoid
0.000 0.747 0.253
E89.2 Postprocedural hypoparathyroidism
0.000 0.748 0.252
L12.0 Bullous pemphigoid
0.000 0.749 0.251
L50-L54 Urticaria and erythema
0.000 0.750 0.250
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.752 0.248
E78.4 Other hyperlipidaemia
0.000 0.753 0.247
E78.3 Hyperchylomicronaemia
0.000 0.753 0.247
E74 Other disorders of carbohydrate metabolism
0.000 0.753 0.247
E73 Lactose intolerance
0.000 0.753 0.246
L10.9 Pemphigus, unspecified
0.000 0.754 0.246
L10.8 Other pemphigus
0.000 0.754 0.246
L10.5 Drug-induced pemphigus
0.000 0.754 0.246
L10.4 Pemphigus erythematosus
0.000 0.754 0.246
L10.3 Brazilian pemphigus [fogo selvagem]
0.000 0.754 0.246
L10.2 Pemphigus foliaceus
0.000 0.754 0.246
L10.1 Pemphigus vegetans
0.000 0.754 0.246
L10.0 Pemphigus vulgaris
0.000 0.754 0.246
E51 Thiamine deficiency
0.000 0.756 0.244
E85 Amyloidosis
0.000 0.756 0.244
L11.0 Acquired keratosis follicularis
0.000 0.757 0.243
L11.9 Acantholytic disorder, unspecified
0.000 0.757 0.242
L11.8 Other specified acantholytic disorders
0.000 0.757 0.242
L71 Rosacea
0.000 0.757 0.243
E88.9 Metabolic disorder, unspecified
0.000 0.759 0.241
E78.8 Other disorders of lipoprotein metabolism
0.000 0.760 0.240
L11.1 Transient acantholytic dermatosis [Grover]
0.000 0.763 0.237
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.769 0.231
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.769 0.231
E79.1 Lesch-Nyhan syndrome
0.000 0.769 0.231
E56 Other vitamin deficiencies
0.000 0.770 0.230
L68 Hypertrichosis
0.000 0.774 0.226
L13.9 Bullous disorder, unspecified
0.000 0.775 0.225
L13.8 Other specified bullous disorders
0.000 0.775 0.225
L13.1 Subcorneal pustular dermatitis
0.000 0.775 0.225
E84.9 Cystic fibrosis, unspecified
0.000 0.776 0.224
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.780 0.220
E50 Vitamin A deficiency
0.000 0.780 0.220
E60 Dietary zinc deficiency
0.000 0.780 0.220
E59 Dietary selenium deficiency
0.000 0.780 0.220
E52 Niacin deficiency [pellagra]
0.000 0.780 0.220
E84.8 Cystic fibrosis with other manifestations
0.000 0.782 0.218
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.782 0.218
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.782 0.218
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.785 0.215
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.787 0.213
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.787 0.213
E70.3 Albinism
0.000 0.787 0.213
E70.2 Disorders of tyrosine metabolism
0.000 0.787 0.213
E70.1 Other hyperphenylalaninaemias
0.000 0.787 0.213
E70.0 Classical phenylketonuria
0.000 0.787 0.213
E71.3 Disorders of fatty-acid metabolism
0.000 0.787 0.213
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.787 0.213
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.787 0.213
E71.0 Maple-syrup-urine disease
0.000 0.787 0.213
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.787 0.213
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.787 0.213
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.787 0.213
E76.2 Other mucopolysaccharidoses
0.000 0.787 0.213
E76.1 Mucopolysaccharidosis, type II
0.000 0.787 0.213
E76.0 Mucopolysaccharidosis, type I
0.000 0.787 0.213
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.787 0.213
E77.8 Other disorders of glycoprotein metabolism
0.000 0.787 0.213
E77.1 Defects in glycoprotein degradation
0.000 0.787 0.213
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.787 0.213
E80.4 Gilbert's syndrome
0.000 0.787 0.213
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.789 0.211
L71.9 Rosacea, unspecified
0.000 0.790 0.210
E63 Other nutritional deficiencies
0.000 0.791 0.209
M07.5 Arthropathy in ulcerative colitis
0.000 0.793 0.207
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.793 0.207
M07.2 Psoriatic spondylitis
0.000 0.793 0.207
M07.1 Arthritis mutilans
0.000 0.793 0.207
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.793 0.207
C43.8 Overlapping malignant melanoma of skin
0.000 0.793 0.207
C43.0 Malignant melanoma of lip
0.000 0.793 0.207
C43.9 Malignant melanoma of skin, unspecified
0.000 0.794 0.206
L63 Alopecia areata
0.000 0.794 0.206
L51 Erythema multiforme
0.000 0.794 0.206
E80.6 Other disorders of bilirubin metabolism
0.000 0.795 0.205
E75.6 Lipid storage disorder, unspecified
0.000 0.796 0.203
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.796 0.203
E75.3 Sphingolipidosis, unspecified
0.000 0.796 0.203
E75.1 Other gangliosidosis
0.000 0.796 0.203
E75.0 GM2 gangliosidosis
0.000 0.796 0.203
L75 Apocrine sweat disorders
0.000 0.797 0.203
L74 Eccrine sweat disorders
0.000 0.797 0.203
L67 Hair colour and hair shaft abnormalities
0.000 0.797 0.203
L64 Androgenic alopecia
0.000 0.797 0.203
L62 Nail disorders in diseases classified elsewhere
0.000 0.797 0.203
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.797 0.203
E51.2 Wernicke's encephalopathy
0.000 0.801 0.199
E75.2 Other sphingolipidosis
0.000 0.801 0.199
E54 Ascorbic acid deficiency
0.000 0.802 0.198
L60 Nail disorders
0.000 0.802 0.198
E03.5 Myxoedema coma
0.000 0.803 0.197
E03.4 Atrophy of thyroid (acquired)
0.000 0.803 0.197
E03.3 Postinfectious hypothyroidism
0.000 0.803 0.197
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.803 0.196
E80.5 Crigler-Najjar syndrome
0.000 0.803 0.196
E80.3 Defects of catalase and peroxydase
0.000 0.803 0.196
E80.0 Hereditary erythropoietic porphyria
0.000 0.803 0.196
L13.0 Dermatitis herpetiformis
0.000 0.804 0.195
E75.5 Other lipid storage disorders
0.000 0.805 0.194
E55 Vitamin D deficiency
0.000 0.806 0.193
C43.4 Malignant melanoma of scalp and neck
0.000 0.808 0.192
E58 Dietary calcium deficiency
0.000 0.808 0.192
M07.6 Other enteropathic arthropathies
0.000 0.808 0.191
E03.1 Congenital hypothyroidism without goitre
0.000 0.809 0.191
E11.4 With neurological complications
0.000 0.809 0.191
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.811 0.189
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.812 0.188
L70 Acne
0.000 0.813 0.186
L68.0 Hirsutism
0.000 0.814 0.186
L60.9 Nail disorder, unspecified
0.000 0.814 0.186
E03.8 Other specified hypothyroidism
0.000 0.815 0.185
E85.4 Organ-limited amyloidosis
0.000 0.817 0.183
L71.1 Rhinophyma
0.000 0.817 0.183
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.818 0.182
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.818 0.182
E72.5 Disorders of glycine metabolism
0.000 0.818 0.182
E72.4 Disorders of ornithine metabolism
0.000 0.818 0.182
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.818 0.182
E72.2 Disorders of urea cycle metabolism
0.000 0.818 0.182
L54 Erythema in diseases classified elsewhere
0.000 0.821 0.179
E72.0 Disorders of amino-acid transport
0.000 0.821 0.179
E80.1 Porphyria cutanea tarda
0.000 0.822 0.178
L65 Other nonscarring hair loss
0.000 0.822 0.177
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.823 0.177
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.823 0.177
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.823 0.177
E74.2 Disorders of galactose metabolism
0.000 0.823 0.177
E74.1 Disorders of fructose metabolism
0.000 0.823 0.177
E73.8 Other lactose intolerance
0.000 0.823 0.177
E73.1 Secondary lactase deficiency
0.000 0.823 0.177
E73.0 Congenital lactase deficiency
0.000 0.823 0.177
E51.9 Thiamine deficiency, unspecified
0.000 0.825 0.175

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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