TreeWAS – Variant ID: rs2857595

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
K70-K77 Diseases of liver	1.000	0.000	0.000
H30-H36 Disorders of choroid and retina	1.000	0.000	0.000
E20-E35 Disorders of other endocrine glands	1.000	0.000	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
E27 Other disorders of adrenal gland	1.000	0.000	0.000
E27.1 Primary adrenocortical insufficiency	1.000	0.000	0.000
Chapter XI Diseases of the digestive system	0.999	0.001	0.000
E16.2 Hypoglycaemia, unspecified	0.999	0.001	0.000
D69 Purpura and other haemorrhagic conditions	0.999	0.001	0.000
E14 Unspecified diabetes mellitus	0.999	0.001	0.000
K75 Other inflammatory liver diseases	0.999	0.001	0.000
Chapter I Certain infectious and parasitic diseases	0.998	0.002	0.000
M35.0 Sicca syndrome [Sjogren]	0.998	0.002	0.000
D80-D89 Certain disorders involving the immune mechanism	0.997	0.003	0.000
K75.4 Autoimmune hepatitis	0.997	0.003	0.000
E10.1 With ketoacidosis	0.997	0.003	0.000
M20.1 Hallux valgus (acquired)	0.000	0.004	0.996
M35 Other systemic involvement of connective tissue	0.996	0.004	0.000
D60-D64 Aplastic and other anaemias	0.995	0.005	0.000
E14.3 With ophthalmic complications	0.994	0.006	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.994	0.006	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.994	0.006	0.000
M20-M25 Other joint disorders	0.994	0.006	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.994	0.006	0.000
B35-B49 Mycoses	0.994	0.006	0.000
H36 Retinal disorders in diseases classified elsewhere	0.993	0.007	0.000
M20 Acquired deformities of fingers and toes	0.001	0.008	0.991
E10.2 With renal complications	0.991	0.009	0.000
D64 Other anaemias	0.991	0.009	0.000
Chapter VI Diseases of the nervous system	0.989	0.011	0.000
G51 Facial nerve disorders	0.989	0.011	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.988	0.012	0.000
H36.0 Diabetic retinopathy	0.988	0.012	0.000
D64.9 Anaemia, unspecified	0.987	0.013	0.000
B37 Candidiasis	0.986	0.014	0.000
E70-E90 Metabolic disorders	0.986	0.014	0.000
G51.0 Bell's palsy	0.986	0.014	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.015	0.985
K50-K52 Noninfective enteritis and colitis	0.983	0.017	0.000
D69.6 Thrombocytopenia, unspecified	0.982	0.018	0.000
K52 Other non-infective gastro-enteritis and colitis	0.982	0.018	0.000
K74 Fibrosis and cirrhosis of liver	0.982	0.018	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.022	0.978
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.978	0.022	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.978	0.022	0.000
H34 Retinal vascular occlusions	0.977	0.023	0.000
G56 Mononeuropathies of upper limb	0.976	0.024	0.000
M34 Systemic sclerosis	0.976	0.024	0.000
E89.0 Postprocedural hypothyroidism	0.975	0.025	0.000
G56.0 Carpal tunnel syndrome	0.972	0.028	0.000
H04 Disorders of lachrymal system	0.971	0.029	0.000
K73 Chronic hepatitis, not elsewhere classified	0.970	0.030	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.970	0.030	0.000
B37.8 Candidiasis of other sites	0.969	0.031	0.000
N00-N08 Glomerular diseases	0.967	0.033	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.967	0.033	0.000
N04 Nephrotic syndrome	0.966	0.034	0.000
K74.6 Other and unspecified cirrhosis of liver	0.966	0.034	0.000
N05 Unspecified nephritic syndrome	0.965	0.035	0.000
N04.9 Unspecified	0.961	0.039	0.000
K90-K93 Other diseases of the digestive system	0.960	0.040	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.960	0.040	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.959	0.041	0.000
D86 Sarcoidosis	0.959	0.041	0.000
K90 Intestinal malabsorption	0.958	0.042	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.958	0.042	0.000
M80-M85 Disorders of bone density and structure	0.955	0.045	0.000
H35 Other retinal disorders	0.952	0.048	0.000
J45.9 Asthma, unspecified	0.952	0.048	0.000
K75.8 Other specified inflammatory liver diseases	0.952	0.048	0.000
E10.4 With neurological complications	0.951	0.049	0.000
K90.9 Intestinal malabsorption, unspecified	0.950	0.050	0.000
J45 Asthma	0.944	0.056	0.000
H35.8 Other specified retinal disorders	0.942	0.058	0.000
J40-J47 Chronic lower respiratory diseases	0.942	0.058	0.000
M80 Osteoporosis with pathological fracture	0.942	0.058	0.000
D68 Other coagulation defects	0.942	0.058	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.942	0.058	0.000
D50-D53 Nutritional anaemias	0.940	0.060	0.000
J44 Other chronic obstructive pulmonary disease	0.939	0.061	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.939	0.061	0.000
H06.2 Dysthyroid exophthalmos	0.936	0.064	0.000
L10-L14 Bullous disorders	0.934	0.066	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.933	0.067	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.932	0.068	0.000
Chapter X Diseases of the respiratory system	0.932	0.068	0.000
E22 Hyperfunction of pituitary gland	0.930	0.070	0.000
E88 Other metabolic disorders	0.930	0.070	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.929	0.071	0.000
B37.9 Candidiasis, unspecified	0.926	0.074	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.925	0.075	0.000
D80 Immunodeficiency with predominantly antibody defects	0.923	0.077	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.923	0.077	0.000
B15-B19 Viral hepatitis	0.922	0.078	0.000
N05.2 Diffuse membranous glomerulonephritis	0.922	0.078	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.916	0.084	0.000
L13 Other bullous disorders	0.916	0.084	0.000
N05.9 Unspecified	0.916	0.084	0.000
H50 Other strabismus	0.915	0.085	0.000
H34.2 Other retinal artery occlusions	0.914	0.086	0.000
H05 Disorders of orbit	0.912	0.088	0.000
D69.4 Other primary thrombocytopenia	0.912	0.088	0.000
G30-G32 Other degenerative diseases of the nervous system	0.910	0.090	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.910	0.090	0.000
A63.0 Anogenital (venereal) warts	0.908	0.092	0.000
L20-L30 Dermatitis and eczema	0.908	0.092	0.000
H52 Disorders of refraction and accommodation	0.905	0.095	0.000
D86.9 Sarcoidosis, unspecified	0.904	0.096	0.000
L13.0 Dermatitis herpetiformis	0.903	0.097	0.000
E23 Hypofunction and other disorders of pituitary gland	0.903	0.097	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.899	0.101	0.000
D70 Agranulocytosis	0.898	0.102	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.897	0.103	0.000
K70 Alcoholic liver disease	0.895	0.105	0.000
H52.1 Myopia	0.894	0.106	0.000
L50-L54 Urticaria and erythema	0.887	0.113	0.000
B44 Aspergillosis	0.887	0.113	0.000
M32 Systemic lupus erythematosus	0.887	0.113	0.000
K60.2 Anal fissure, unspecified	0.886	0.114	0.000
M34.9 Systemic sclerosis, unspecified	0.884	0.116	0.000
E06 Thyroiditis	0.883	0.116	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.883	0.117	0.000
E83.1 Disorders of iron metabolism	0.000	0.117	0.883
E10.0 With coma	0.882	0.118	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.878	0.122	0.000
N05.1 Focal and segmental glomerular lesions	0.878	0.122	0.000
D50 Iron deficiency anaemia	0.878	0.122	0.000
E14.2 Withrenal complications	0.877	0.123	0.000
H04.1 Other disorders of lachrymal gland	0.876	0.124	0.000
H04.4 Chronic inflammation of lachrymal passages	0.876	0.124	0.000
H34.8 Other retinal vascular occlusions	0.876	0.124	0.000
D61 Other aplastic anaemias	0.872	0.128	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.871	0.129	0.000
D68.8 Other specified coagulation defects	0.870	0.130	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.869	0.131	0.000
D55-D59 Haemolytic anaemias	0.867	0.133	0.000
E78.2 Mixed hyperlipidaemia	0.865	0.135	0.000
D69.2 Other nonthrombocytopenic purpura	0.862	0.138	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.862	0.138	0.000
K73.9 Chronic hepatitis, unspecified	0.862	0.138	0.000
H04.8 Other disorders of lachrymal system	0.860	0.140	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.858	0.142	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.857	0.143	0.000
L28 Lichen simplex chronicus and prurigo	0.857	0.143	0.000
M34.8 Other forms of systemic sclerosis	0.856	0.144	0.000
H18 Other disorders of cornea	0.855	0.145	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.853	0.147	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.852	0.148	0.000
D50.9 Iron deficiency anaemia, unspecified	0.851	0.149	0.000
E13 Other specified diabetes mellitus	0.850	0.150	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.850	0.150	0.000
K72 Hepatic failure, not elsewhere classified	0.849	0.151	0.000
M34.1 CR(E)ST syndrome	0.847	0.153	0.000
E07 Other disorders of thyroid	0.847	0.153	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.846	0.154	0.000
A30-A49 Other bacterial diseases	0.844	0.156	0.000
E23.6 Other disorders of pituitary gland	0.843	0.157	0.000
D73 Diseases of spleen	0.843	0.157	0.000
D68.0 Von Willebrand's disease	0.841	0.159	0.000
E50-E64 Other nutritional deficiencies	0.840	0.160	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.839	0.161	0.000
G51.9 Disorder of facial nerve, unspecified	0.838	0.162	0.000
C81 Hodgkin's disease	0.835	0.165	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.833	0.167	0.000
E14.1 With ketoacidosis	0.830	0.170	0.000
D69.8 Other specified haemorrhagic conditions	0.830	0.170	0.000
B25-B34 Other viral diseases	0.827	0.173	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.827	0.173	0.000
E06.3 Autoimmune thyroiditis	0.827	0.173	0.000
M60-M63 Disorders of muscles	0.826	0.174	0.000
K74.3 Primary biliary cirrhosis	0.826	0.174	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.826	0.174	0.000
H30 Chorioretinal inflammation	0.825	0.175	0.000
G31.8 Other specified degenerative diseases of nervous system	0.824	0.176	0.000
H31 Other disorders of choroid	0.820	0.180	0.000
E10.7 With multiple complications	0.820	0.180	0.000
N04.2 Diffuse membranous glomerulonephritis	0.820	0.180	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.820	0.180	0.000
N04.1 Focal and segmental glomerular lesions	0.819	0.181	0.000
H50.5 Heterophoria	0.818	0.182	0.000
H35.4 Peripheral retinal degeneration	0.817	0.183	0.000
H35.2 Other proliferative retinopathy	0.817	0.183	0.000
B37.0 Candidal stomatitis	0.817	0.183	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.816	0.184	0.000
M35.3 Polymyalgia rheumatica	0.813	0.187	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.812	0.188	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.811	0.189	0.000
H04.9 Disorder of lachrymal system, unspecified	0.811	0.189	0.000
E24 Cushing's syndrome	0.810	0.190	0.000
L40-L45 Papulosquamous disorders	0.778	0.190	0.032
B18 Chronic viral hepatitis	0.810	0.190	0.000
D83 Common variable immunodeficiency	0.809	0.191	0.000
L52 Erythema nodosum	0.807	0.193	0.000
J43 Emphysema	0.807	0.193	0.000
H05.0 Acute inflammation of orbit	0.806	0.194	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.804	0.196	0.000
C83.3 Large cell (diffuse)	0.803	0.197	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.802	0.198	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.802	0.198	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.802	0.198	0.000
D84 Other immunodeficiencies	0.801	0.199	0.000
C85.1 B-cell lymphoma, unspecified	0.801	0.199	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.800	0.200	0.000
G56.1 Other lesions of median nerve	0.798	0.202	0.000
K70.0 Alcoholic fatty liver	0.798	0.202	0.000
E14.8 With unspecified complications	0.797	0.203	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.797	0.203	0.000
G70-G73 Diseases of myoneural junction and muscle	0.795	0.205	0.000
C81.9 Hodgkin's disease, unspecified	0.794	0.206	0.000
B44.1 Other pulmonary aspergillosis	0.793	0.207	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.792	0.208	0.000
M34.0 Progressive systemic sclerosis	0.790	0.209	0.000
H50.2 Vertical strabismus	0.790	0.210	0.000
E31 Polyglandular dysfunction	0.789	0.210	0.000
N03 Chronic nephritic syndrome	0.788	0.212	0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.786	0.214	0.000
J86 Pyothorax	0.786	0.214	0.000
K70.3 Alcoholic cirrhosis of liver	0.781	0.219	0.000
K90.8 Other intestinal malabsorption	0.780	0.220	0.000
M35.7 Hypermobility syndrome	0.779	0.221	0.000
H05.2 Exophthalmic conditions	0.778	0.222	0.000
E14.9 Without complications	0.778	0.222	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.777	0.223	0.000
D86.0 Sarcoidosis of lung	0.776	0.224	0.000
E73 Lactose intolerance	0.776	0.224	0.000
L28.0 Lichen simplex chronicus	0.776	0.224	0.000
M00-M03 Infectious arthropathies	0.776	0.224	0.000
E78.4 Other hyperlipidaemia	0.776	0.224	0.000
D59 Acquired haemolytic anaemia	0.774	0.226	0.000
D68.6 Other Thrombophilia	0.773	0.227	0.000
H35.0 Background retinopathy and retinal vascular changes	0.773	0.227	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.771	0.229	0.000
G31.0 Circumscribed brain atrophy	0.771	0.229	0.000
E14.5 With peripheral circulatory complications	0.767	0.233	0.000
E22.0 Acromegaly and pituitary gigantism	0.767	0.233	0.000
E23.2 Diabetes insipidus	0.767	0.233	0.000
D86.3 Sarcoidosis of skin	0.766	0.234	0.000
L20 Atopic dermatitis	0.766	0.234	0.000
B16 Acute hepatitis B	0.766	0.234	0.000
E07.8 Other specified disorders of thyroid	0.765	0.235	0.000
H16 Keratitis	0.765	0.235	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.763	0.237	0.000
D62 Acute posthaemorrhagic anaemia	0.763	0.237	0.000
D61.9 Aplastic anaemia, unspecified	0.762	0.238	0.000
D64.8 Other specified anaemias	0.762	0.238	0.000
G59.0 Diabetic mononeuropathy	0.761	0.239	0.000
C81.1 Nodular sclerosis	0.761	0.239	0.000
K72.0 Acute and subacute hepatic failure	0.760	0.240	0.000
E78.1 Pure hyperglyceridaemia	0.758	0.242	0.000
E89.3 Postprocedural hypopituitarism	0.758	0.242	0.000
K60 Fissure and fistula of anal and rectal regions	0.758	0.242	0.000
M35.1 Other overlap syndromes	0.757	0.243	0.000
B35 Dermatophytosis	0.757	0.243	0.000
C88 Malignant immunoproliferative diseases	0.756	0.244	0.000
D73.5 Infarction of spleen	0.756	0.244	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.754	0.246	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.753	0.247	0.000
E40-E46 Malnutrition	0.751	0.249	0.000
M82 Osteoporosis in diseases classified elsewhere	0.751	0.249	0.000
A65-A69 Other spirochaetal diseases	0.750	0.250	0.000
E88.2 Lipomatosis, not elsewhere classified	0.750	0.250	0.000
E78.6 Lipoprotein deficiency	0.749	0.251	0.000
G56.8 Other mononeuropathies of upper limb	0.749	0.251	0.000
H34.1 Central retinal artery occlusion	0.748	0.252	0.000
L28.1 Prurigo nodularis	0.748	0.252	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.747	0.253	0.000
B37.7 Candidal septicaemia	0.747	0.253	0.000
G56.4 Causalgia	0.746	0.254	0.000
D52 Folate deficiency anaemia	0.745	0.254	0.000
H50.9 Strabismus, unspecified	0.745	0.255	0.000
H18.6 Keratoconus	0.745	0.255	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.744	0.256	0.000
E13.9 Without complications	0.742	0.258	0.000
H34.9 Retinal vascular occlusion, unspecified	0.742	0.258	0.000
B25 Cytomegaloviral disease	0.741	0.259	0.000
E10.8 With unspecified complications	0.738	0.262	0.000
R63.4 Abnormal weight loss	0.737	0.263	0.000
J45.1 Nonallergic asthma	0.735	0.265	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.734	0.266	0.000
D69.0 Allergic purpura	0.733	0.267	0.000
H18.8 Other specified disorders of cornea	0.732	0.268	0.000
E16.1 Other hypoglycaemia	0.731	0.268	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.731	0.269	0.000
E10.6 With other specified complications	0.730	0.269	0.000
H50.6 Mechanical strabismus	0.730	0.270	0.000
L29 Pruritus	0.729	0.271	0.000
L43 Lichen planus	0.717	0.271	0.012
A15-A19 Tuberculosis	0.727	0.272	0.000
M20.3 Other deformity of hallux (acquired)	0.000	0.273	0.727
B18.1 Chronic viral hepatitis B without delta-agent	0.727	0.273	0.000
E27.9 Disorder of adrenal gland, unspecified	0.727	0.273	0.000
H15 Disorders of sclera	0.725	0.275	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.723	0.277	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.721	0.278	0.000
E84 Cystic fibrosis	0.721	0.279	0.000
D69.9 Haemorrhagic condition, unspecified	0.720	0.280	0.000
B37.1 Pulmonary candidiasis	0.720	0.280	0.000
D50.1 Sideropenic dysphagia	0.719	0.281	0.000
M83 Adult osteomalacia	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
D73.1 Hypersplenism	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
K77 Liver disorders in diseases classified elsewhere	0.717	0.283	0.000
K71 Toxic liver disease	0.717	0.283	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.717	0.283	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.717	0.283	0.000
E32 Diseases of thymus	0.717	0.283	0.000
E30 Disorders of puberty, not elsewhere classified	0.717	0.283	0.000
E25 Adrenogenital disorders	0.717	0.283	0.000
D67 Hereditary factor IX deficiency	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
E27.5 Adrenomedullary hyperfunction	0.717	0.283	0.000
E27.0 Other adrenocortical overactivity	0.717	0.283	0.000
D69.1 Qualitative platelet defects	0.716	0.284	0.000
E14.7 With multiple complications	0.716	0.284	0.000
E14.0 With coma	0.716	0.284	0.000
K75.2 Nonspecific reactive hepatitis	0.716	0.284	0.000
K75.1 Phlebitis of portal vein	0.716	0.284	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.716	0.284	0.000
A75-A79 Rickettsioses	0.716	0.284	0.000
A70-A74 Other diseases caused by chlamydiae	0.716	0.284	0.000
A20-A28 Certain zoonotic bacterial diseases	0.716	0.284	0.000
D81 Combined immunodeficiencies	0.715	0.285	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.714	0.286	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.714	0.286	0.000
M35.5 Multifocal fibrosclerosis	0.714	0.286	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.714	0.286	0.000
D69.5 Secondary thrombocytopenia	0.714	0.286	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.714	0.286	0.000
H46 Optic neuritis	0.713	0.287	0.000
M15-M19 Arthrosis	0.713	0.287	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.713	0.287	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.712	0.287	0.000
B48 Other mycoses, not elsewhere classified	0.712	0.288	0.000
B47 Mycetoma	0.712	0.288	0.000
B46 Zygomycosis	0.712	0.288	0.000
B45 Cryptococcosis	0.712	0.288	0.000
B43 Chromomycosis and phaeomycotic abscess	0.712	0.288	0.000
B42 Sporotrichosis	0.712	0.288	0.000
B41 Paracoccidioidomycosis	0.712	0.288	0.000
B40 Blastomycosis	0.712	0.288	0.000
B39 Histoplasmosis	0.712	0.288	0.000
B38 Coccidioidomycosis	0.712	0.288	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.712	0.288	0.000
B17 Other acute viral hepatitis	0.712	0.288	0.000
D64.4 Congenital dyserythropoietic anaemia	0.710	0.289	0.000
D64.3 Other sideroblastic anaemias	0.710	0.289	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.710	0.289	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.710	0.289	0.000
D64.0 Hereditary sideroblastic anaemia	0.710	0.289	0.000
E88.9 Metabolic disorder, unspecified	0.710	0.290	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.709	0.290	0.000
C83.0 Small cell (diffuse)	0.709	0.290	0.000
J43.8 Other emphysema	0.709	0.291	0.000
G51.4 Facial myokymia	0.709	0.291	0.000
G51.2 Melkersson's syndrome	0.709	0.291	0.000
G51.1 Geniculate ganglionitis	0.709	0.291	0.000
D82 Immunodeficiency associated with other major defects	0.708	0.292	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.708	0.292	0.000
B37.6 Candidal endocarditis	0.707	0.293	0.000
B37.5 Candidal meningitis	0.707	0.293	0.000
K60.5 Anorectal fistula	0.707	0.293	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.707	0.293	0.000
E77 Disorders of glycoprotein metabolism	0.707	0.293	0.000
E76 Disorders of glycosaminoglycan metabolism	0.707	0.293	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.707	0.293	0.000
E72 Other disorders of amino-acid metabolism	0.707	0.293	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.707	0.293	0.000
E70 Disorders of aromatic amino-acid metabolism	0.707	0.293	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.707	0.293	0.000
D68.9 Coagulation defect, unspecified	0.707	0.293	0.000
J43.2 Centrilobular emphysema	0.705	0.295	0.000
G31.2 Degeneration of nervous system due to alcohol	0.704	0.296	0.000
A60 Anogenital herpesviral [herpes simplex] infections	0.704	0.296	0.000
K74.4 Secondary biliary cirrhosis	0.704	0.296	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.704	0.296	0.000
K74.1 Hepatic sclerosis	0.704	0.296	0.000
L12 Pemphigoid	0.703	0.297	0.000
E55 Vitamin D deficiency	0.703	0.297	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.702	0.298	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.701	0.299	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.701	0.299	0.000
E89.5 Postprocedural testicular hypofunction	0.701	0.299	0.000
E89.4 Postprocedural ovarian failure	0.701	0.299	0.000
E89.1 Postprocedural hypoinsulinaemia	0.701	0.299	0.000
H34.0 Transient retinal artery occlusion	0.700	0.299	0.000
C91 Lymphoid leukaemia	0.700	0.300	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.700	0.300	0.000
H30.9 Chorioretinal inflammation, unspecified	0.699	0.301	0.000
B36 Other superficial mycoses	0.699	0.301	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.697	0.303	0.000
M18 Arthrosis of first carpometacarpal joint	0.697	0.303	0.000
J86.9 Pyothorax without fistula	0.697	0.303	0.000
E14.6 With other specified complications	0.697	0.303	0.000
H04.6 Other changes in lachrymal passages	0.696	0.304	0.000
H04.0 Dacryoadenitis	0.696	0.304	0.000
E20 Hypoparathyroidism	0.696	0.304	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.696	0.304	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.696	0.304	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.696	0.304	0.000
D86.1 Sarcoidosis of lymph nodes	0.696	0.304	0.000
D61.1 Drug-induced aplastic anaemia	0.695	0.305	0.000
A48 Other bacterial diseases, not elsewhere classified	0.695	0.305	0.000
M81 Osteoporosis without pathological fracture	0.695	0.305	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.694	0.306	0.000
N06 Isolated proteinuria with specified morphological lesion	0.694	0.306	0.000
N01 Rapidly progressive nephritic syndrome	0.694	0.306	0.000
N00 Acute nephritic syndrome	0.694	0.306	0.000
N04.8 Other	0.693	0.307	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.693	0.307	0.000
N04.6 Dense deposit disease	0.693	0.307	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.693	0.307	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.693	0.307	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.693	0.307	0.000
N04.0 Minor glomerular abnormality	0.693	0.307	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.693	0.307	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.692	0.308	0.000
N05.6 Dense deposit disease	0.692	0.308	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.692	0.308	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.692	0.308	0.000
N05.0 Minor glomerular abnormality	0.692	0.308	0.000
E24.2 Drug-induced Cushing's syndrome	0.692	0.308	0.000
L53 Other erythematous conditions	0.692	0.308	0.000
H50.0 Convergent concomitant strabismus	0.691	0.309	0.000
L10 Pemphigus	0.690	0.309	0.000
H18.4 Corneal degeneration	0.690	0.310	0.000
H51 Other disorders of binocular movement	0.688	0.311	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.688	0.311	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.688	0.311	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.688	0.311	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.688	0.311	0.000
G52 Disorders of other cranial nerves	0.688	0.312	0.000
E27.2 Addisonian crisis	0.688	0.312	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.688	0.312	0.000
E88.3 Tumour lysis syndrome	0.688	0.312	0.000
A59 Trichomoniasis	0.688	0.312	0.000
A56 Other sexually transmitted chlamydial diseases	0.688	0.312	0.000
A54 Gonococcal infection	0.688	0.312	0.000
A53 Other and unspecified syphilis	0.688	0.312	0.000
A52 Late syphilis	0.688	0.312	0.000
A51 Early syphilis	0.688	0.312	0.000
A50 Congenital syphilis	0.688	0.312	0.000
A64 Unspecified sexually transmitted disease	0.688	0.312	0.000
A58 Granuloma inguinale	0.688	0.312	0.000
A57 Chancroid	0.688	0.312	0.000
A55 Chlamydial lymphogranuloma (venereum)	0.688	0.312	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.688	0.312	0.000
K70.9 Alcoholic liver disease, unspecified	0.688	0.312	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.688	0.312	0.000
K90.3 Pancreatic steatorrhoea	0.687	0.313	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.687	0.313	0.000
K90.1 Tropical sprue	0.687	0.313	0.000
K90.0 Coeliac disease	0.687	0.313	0.000
A41 Other septicaemia	0.686	0.314	0.000
M32.8 Other forms of systemic lupus erythematosus	0.686	0.314	0.000
E51 Thiamine deficiency	0.685	0.315	0.000
B44.9 Aspergillosis, unspecified	0.683	0.316	0.000
D53 Other nutritional anaemias	0.683	0.317	0.000
N03.1 Focal and segmental glomerular lesions	0.683	0.317	0.000
H18.1 Bullous keratopathy	0.683	0.317	0.000
H35.1 Retinopathy of prematurity	0.682	0.317	0.000
H50.8 Other specified strabismus	0.682	0.318	0.000
H05.8 Other disorders of orbit	0.682	0.318	0.000
L23 Allergic contact dermatitis	0.681	0.319	0.000
D86.8 Sarcoidosis of other and combined sites	0.680	0.320	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.680	0.320	0.000
E28 Ovarian dysfunction	0.680	0.320	0.000
B37.4 Candidiasis of other urogenital sites	0.679	0.321	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations