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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28895095
log Bayes Factor = 135.019
Chromosome 6   position 32,418,848  (GRCh37) Explore rs28895095 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
M07.3 Other psoriatic arthropathies
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.999 0.001 0.000
K50 Crohn's disease [regional enteritis]
0.999 0.001 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.999 0.001 0.000
K50-K52 Noninfective enteritis and colitis
0.999 0.001 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
C43-C44 Melanoma and other malignant neoplasms of skin
0.999 0.001 0.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
C44.7 Skin of lower limb, including hip
0.999 0.001 0.000
K50.1 Crohn's disease of large intestine
0.998 0.002 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.998 0.002 0.000
D86 Sarcoidosis
0.000 0.002 0.998
D86.9 Sarcoidosis, unspecified
0.000 0.002 0.998
M07.30 Other psoriatic arthropathies (Multiple sites)
0.997 0.003 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.996 0.004 0.000
Chapter II Neoplasms
0.996 0.004 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.994 0.006 0.000
M06.0 Seronegative rheumatoid arthritis
0.993 0.007 0.000
D50-D53 Nutritional anaemias
0.000 0.008 0.992
C44.2 Skin of ear and external auricular canal
0.992 0.008 0.000
C83.3 Large cell (diffuse)
0.991 0.009 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.990 0.010 0.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.010 0.989
C44.5 Skin of trunk
0.989 0.011 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.012 0.988
D50 Iron deficiency anaemia
0.000 0.012 0.988
D50.9 Iron deficiency anaemia, unspecified
0.000 0.013 0.987
C44.4 Skin of scalp and neck
0.986 0.014 0.000
K51.4 Pseudopolyposis of colon
0.986 0.014 0.000
D86.0 Sarcoidosis of lung
0.000 0.015 0.985
D51 Vitamin B12 deficiency anaemia
0.000 0.015 0.985
C73 Malignant neoplasm of thyroid gland
0.984 0.016 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.984 0.016 0.000
E10.1 With ketoacidosis
0.000 0.021 0.979
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.975 0.025 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.026 0.974
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.027 0.973
K50.9 Crohn's disease, unspecified
0.968 0.032 0.000
K90 Intestinal malabsorption
0.000 0.033 0.967
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.036 0.964
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.956 0.044 0.000
C82.0 Small cleaved cell, follicular
0.955 0.045 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.046 0.954
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.948 0.052 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.944 0.056 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.068 0.932
K90.9 Intestinal malabsorption, unspecified
0.000 0.069 0.931
M05 Seropositive rheumatoid arthritis
0.929 0.071 0.000
Z93.2 Ileostomy status
0.920 0.080 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.081 0.919
C43 Malignant melanoma of skin
0.915 0.085 0.000
M06.3 Rheumatoid nodule
0.914 0.086 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.912 0.088 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.907 0.093 0.000
K51.2 Ulcerative (chronic) proctitis
0.906 0.094 0.000
J45 Asthma
0.000 0.094 0.906
M07.36 Other psoriatic arthropathies (Lower leg)
0.901 0.099 0.000
L40-L45 Papulosquamous disorders
0.861 0.117 0.021
M05.9 Seropositive rheumatoid arthritis, unspecified
0.879 0.121 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.875 0.125 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.866 0.134 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.865 0.135 0.000
C02.9 Tongue, unspecified
0.864 0.136 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.863 0.137 0.000
J45.0 Predominantly allergic asthma
0.000 0.142 0.858
M06.98 Rheumatoid arthritis, unspecified (Other)
0.858 0.142 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.144 0.856
E10.4 With neurological complications
0.000 0.147 0.853
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.850 0.150 0.000
D52 Folate deficiency anaemia
0.000 0.151 0.849
C06 Malignant neoplasm of other and unspecified parts of mouth
0.849 0.151 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.154 0.846
C82.2 Large cell, follicular
0.841 0.159 0.000
T42.4 Benzodiazepines
0.838 0.162 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.837 0.163 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.164 0.836
K50.8 Other Crohn's disease
0.825 0.175 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.823 0.177 0.000
E14 Unspecified diabetes mellitus
0.000 0.178 0.822
C82.3 Follicular lymphoma grade IIIa
0.819 0.181 0.000
K51.5 Mucosal proctocolitis
0.819 0.181 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.817 0.183 0.000
K51.8 Other ulcerative colitis
0.817 0.183 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.814 0.186 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.192 0.808
M06.37 Rheumatoid nodule (Ankle and foot)
0.803 0.197 0.000
C02.2 Ventral surface of tongue
0.795 0.205 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.206 0.794
C44.0 Skin of lip
0.793 0.207 0.000
E10.0 With coma
0.000 0.207 0.793
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.208 0.792
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.783 0.217 0.000
E07 Other disorders of thyroid
0.000 0.219 0.781
E10.5 With peripheral circulatory complications
0.000 0.221 0.779
C02.1 Border of tongue
0.779 0.221 0.000
E10.8 With unspecified complications
0.000 0.224 0.776
L43 Lichen planus
0.766 0.225 0.009
E20-E35 Disorders of other endocrine glands
0.000 0.228 0.772
T36-T50 Poisoning by drugs, medicaments and biological substances
0.770 0.230 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.761 0.239 0.000
E05.8 Other thyrotoxicosis
0.000 0.240 0.760
M11 Other crystal arthropathies
0.758 0.242 0.000
C44.1 Skin of eyelid, including canthus
0.757 0.243 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.755 0.245 0.000
C74 Malignant neoplasm of adrenal gland
0.755 0.245 0.000
L40.3 Pustulosis palmaris et plantaris
0.754 0.246 0.000
C05 Malignant neoplasm of palate
0.754 0.246 0.000
L42 Pityriasis rosea
0.741 0.248 0.011
C75 Malignant neoplasm of other endocrine glands and related structures
0.747 0.253 0.000
D52.9 Folate deficiency anaemia, unspecified
0.000 0.254 0.746
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.745 0.255 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.745 0.255 0.000
C03 Malignant neoplasm of gum
0.744 0.255 0.000
K90.8 Other intestinal malabsorption
0.000 0.256 0.744
L40.1 Generalised pustular psoriasis
0.742 0.257 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.740 0.260 0.000
C12 Malignant neoplasm of pyriform sinus
0.740 0.260 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.740 0.260 0.000
E03.8 Other specified hypothyroidism
0.000 0.261 0.739
C13 Malignant neoplasm of hypopharynx
0.738 0.261 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.738 0.262 0.000
E10.2 With renal complications
0.000 0.262 0.738
C09 Malignant neoplasm of tonsil
0.738 0.262 0.000
D69 Purpura and other haemorrhagic conditions
0.000 0.263 0.737
E27 Other disorders of adrenal gland
0.000 0.263 0.737
M12 Other specific arthropathies
0.736 0.264 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.735 0.265 0.000
C10 Malignant neoplasm of oropharynx
0.734 0.266 0.000
C06.0 Cheek mucosa
0.732 0.268 0.000
C02.4 Lingual tonsil
0.727 0.273 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.726 0.274 0.000
M14 Arthropathies in other diseases classified elsewhere
0.726 0.274 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.721 0.279 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.279 0.721
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.719 0.281 0.000
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
C82.6 Cutaneous follicle centre lymphoma
0.717 0.283 0.000
C82.5 Diffuse follicle centre lymphoma
0.717 0.283 0.000
C82.4 Follicular lymphoma grade IIIb
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C93 Monocytic leukaemia
0.717 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.717 0.283 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.717 0.283 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.717 0.283 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.717 0.283 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.717 0.283 0.000
M07.5 Arthropathy in ulcerative colitis
0.717 0.283 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.717 0.283 0.000
M07.2 Psoriatic spondylitis
0.717 0.283 0.000
M07.1 Arthritis mutilans
0.717 0.283 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.716 0.284 0.000
C85.0 Lymphosarcoma
0.716 0.284 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.284 0.716
E13 Other specified diabetes mellitus
0.000 0.284 0.716
E10.6 With other specified complications
0.000 0.286 0.714
C83.7 Burkitt's tumour
0.713 0.287 0.000
C83.6 Undifferentiated (diffuse)
0.713 0.287 0.000
C83.5 Lymphoblastic (diffuse)
0.713 0.287 0.000
C83.4 Immunoblastic (diffuse)
0.713 0.287 0.000
C83.2 Mixed small and large cell (diffuse)
0.713 0.287 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.712 0.288 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.712 0.288 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.712 0.288 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.712 0.288 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.712 0.288 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.712 0.288 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.712 0.288 0.000
M06.34 Rheumatoid nodule (Hand)
0.712 0.288 0.000
D82 Immunodeficiency associated with other major defects
0.000 0.290 0.709
D81 Combined immunodeficiencies
0.000 0.290 0.709
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.708 0.292 0.000
D50.1 Sideropenic dysphagia
0.000 0.292 0.708
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.293 0.706
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.293 0.706
D51.2 Transcobalamin II deficiency
0.000 0.293 0.706
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.293 0.706
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.702 0.298 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.702 0.298 0.000
C11 Malignant neoplasm of nasopharynx
0.699 0.301 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.699 0.301 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.699 0.301 0.000
L43.9 Lichen planus, unspecified
0.697 0.302 0.001
E15 Nondiabetic hypoglycaemic coma
0.000 0.302 0.698
E14.9 Without complications
0.000 0.304 0.696
C00 Malignant neoplasm of lip
0.696 0.304 0.000
C64-C68 Malignant neoplasms of urinary tract
0.696 0.304 0.000
C43.4 Malignant melanoma of scalp and neck
0.695 0.305 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.695 0.305 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.307 0.693
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.307 0.693
K90.1 Tropical sprue
0.000 0.307 0.693
D69.6 Thrombocytopenia, unspecified
0.000 0.307 0.693
E14.3 With ophthalmic complications
0.000 0.310 0.690
E40-E46 Malnutrition
0.000 0.310 0.690
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.689 0.310 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.687 0.312 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.316 0.684
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.316 0.684
E16.4 Abnormal secretion of gastrin
0.000 0.316 0.684
E16.3 Increased secretion of glucagon
0.000 0.316 0.684
D53 Other nutritional anaemias
0.000 0.317 0.683
G35 Multiple sclerosis
0.000 0.318 0.682
L40.8 Other psoriasis
0.680 0.319 0.000
C02.8 Overlapping lesion of tongue
0.676 0.323 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.676 0.323 0.000
C02.0 Dorsal surface of tongue
0.676 0.323 0.000
E16.1 Other hypoglycaemia
0.000 0.324 0.676
C43.7 Malignant melanoma of lower limb, including hip
0.670 0.330 0.000
C04 Malignant neoplasm of floor of mouth
0.669 0.330 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.668 0.331 0.000
E06 Thyroiditis
0.000 0.333 0.667
M05.8 Other seropositive rheumatoid arthritis
0.666 0.334 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.666 0.334 0.000
M05.2 Rheumatoid vasculitis
0.666 0.334 0.000
M05.1 Rheumatoid lung disease
0.666 0.334 0.000
M05.0 Felty's syndrome
0.666 0.334 0.000
L40.0 Psoriasis vulgaris
0.665 0.335 0.000
D86.3 Sarcoidosis of skin
0.000 0.343 0.657
C83.1 Small cleaved cell (diffuse)
0.656 0.343 0.000
C43.8 Overlapping malignant melanoma of skin
0.656 0.344 0.000
C43.0 Malignant melanoma of lip
0.656 0.344 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.655 0.345 0.000
M06.38 Rheumatoid nodule (Other)
0.655 0.345 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.655 0.345 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.655 0.345 0.000
M06.33 Rheumatoid nodule (Forearm)
0.655 0.345 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.655 0.345 0.000
C88 Malignant immunoproliferative diseases
0.655 0.345 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.653 0.347 0.000
D83 Common variable immunodeficiency
0.000 0.347 0.653
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.652 0.348 0.000
C85.1 B-cell lymphoma, unspecified
0.650 0.350 0.000
J45.8 Mixed asthma
0.000 0.351 0.649
J45.1 Nonallergic asthma
0.000 0.351 0.649
D69.9 Haemorrhagic condition, unspecified
0.000 0.351 0.649
C01 Malignant neoplasm of base of tongue
0.648 0.352 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.647 0.353 0.000
C06.2 Retromolar area
0.646 0.354 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.646 0.354 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.644 0.356 0.000
# Top node
0.094 0.357 0.549
K51.0 Ulcerative (chronic) enterocolitis
0.636 0.364 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.633 0.367 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.367 0.633
L44 Other papulosquamous disorders
0.618 0.367 0.015
L41 Parapsoriasis
0.618 0.367 0.015
L45 Papulosquamous disorders in diseases classified elsewhere
0.618 0.367 0.015
C64 Malignant neoplasm of kidney, except renal pelvis
0.631 0.369 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.630 0.370 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.630 0.370 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.630 0.370 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.630 0.370 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.630 0.370 0.000
C06.9 Mouth, unspecified
0.630 0.370 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.629 0.371 0.000
T42.1 Iminostilbenes
0.626 0.374 0.000
E22 Hyperfunction of pituitary gland
0.000 0.375 0.625
C95 Leukaemia of unspecified cell type
0.625 0.375 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.624 0.376 0.000
C69 Malignant neoplasm of eye and adnexa
0.623 0.377 0.000
T42.0 Hydantoin derivatives
0.620 0.380 0.000
D80 Immunodeficiency with predominantly antibody defects
0.000 0.384 0.616
T38.1 Thyroid hormones and substitutes
0.615 0.385 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.387 0.613
C05.0 Hard palate
0.612 0.388 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.611 0.388 0.000
D52.8 Other folate deficiency anaemias
0.000 0.391 0.609
D52.1 Drug-induced folate deficiency anaemia
0.000 0.391 0.609
D52.0 Dietary folate deficiency anaemia
0.000 0.391 0.609
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.609 0.391 0.000
C06.1 Vestibule of mouth
0.609 0.391 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.392 0.608
E50-E64 Other nutritional deficiencies
0.000 0.393 0.607
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.393 0.607
E20 Hypoparathyroidism
0.000 0.394 0.606
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.394 0.606
E29 Testicular dysfunction
0.000 0.397 0.603
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.398 0.602
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.399 0.601
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.600 0.400 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.600 0.400 0.000
T42.3 Barbiturates
0.600 0.400 0.000
T42.2 Succinimides and oxazolidinediones
0.600 0.400 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.127 0.401 0.472
D55-D59 Haemolytic anaemias
0.000 0.402 0.597
T46 Poisoning by agents primarily affecting the cardiovascular system
0.598 0.402 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.594 0.406 0.000
K50.0 Crohn's disease of small intestine
0.593 0.407 0.000
C44.6 Skin of upper limb, including shoulder
0.591 0.409 0.000
E14.8 With unspecified complications
0.000 0.410 0.590
E14.7 With multiple complications
0.000 0.410 0.590
E14.6 With other specified complications
0.000 0.410 0.590
E14.2 Withrenal complications
0.000 0.410 0.590
E14.1 With ketoacidosis
0.000 0.410 0.590
E14.0 With coma
0.000 0.410 0.590
C74.9 Adrenal gland, unspecified
0.586 0.414 0.000
M11.9 Crystal arthropathy, unspecified
0.585 0.415 0.000
E07.8 Other specified disorders of thyroid
0.000 0.419 0.580
C03.1 Lower gum
0.579 0.420 0.000
D69.5 Secondary thrombocytopenia
0.000 0.420 0.579
K51.3 Ulcerative (chronic) rectosigmoiditis
0.578 0.422 0.000
D69.4 Other primary thrombocytopenia
0.000 0.423 0.577
E27.2 Addisonian crisis
0.000 0.427 0.573
C75.9 Endocrine gland, unspecified
0.572 0.428 0.000
T38.0 Glucocorticoids and synthetic analogues
0.572 0.428 0.000
M06.4 Inflammatory polyarthropathy
0.570 0.429 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.570 0.430 0.000
D67 Hereditary factor IX deficiency
0.000 0.430 0.569
C13.9 Hypopharynx, unspecified
0.569 0.431 0.000
C09.9 Tonsil, unspecified
0.568 0.432 0.000
D84 Other immunodeficiencies
0.001 0.433 0.566
T47.1 Other antacids and anti-gastric-secretion drugs
0.567 0.433 0.000
C83.0 Small cell (diffuse)
0.565 0.435 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.563 0.436 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.562 0.438 0.000
C10.9 Oropharynx, unspecified
0.562 0.438 0.000
E07.1 Dyshormogenetic goitre
0.000 0.440 0.560
E07.0 Hypersecretion of calcitonin
0.000 0.440 0.560
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.442 0.557
L43.8 Other lichen planus
0.551 0.443 0.006
L43.3 Subacute (active) lichen planus
0.549 0.444 0.006
L43.2 Lichenoid drug reaction
0.549 0.444 0.006
L43.1 Bullous lichen planus
0.549 0.444 0.006
L43.0 Hypertrophic lichen planus
0.549 0.444 0.006
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.555 0.445 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.446 0.554
E32 Diseases of thymus
0.000 0.446 0.554
E31 Polyglandular dysfunction
0.000 0.446 0.554
E30 Disorders of puberty, not elsewhere classified
0.000 0.446 0.554
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.552 0.448 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.552 0.448 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.552 0.448 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.552 0.448 0.000
Chapter VI Diseases of the nervous system
0.000 0.448 0.552
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.448 0.552
M12.2 Villonodular synovitis (pigmented)
0.547 0.453 0.000
C43.9 Malignant melanoma of skin, unspecified
0.546 0.454 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.456 0.544
M11.8 Other specified crystal arthropathies
0.544 0.456 0.000
M11.1 Familial chondrocalcinosis
0.544 0.456 0.000
M11.0 Hydroxyapatite deposition disease
0.544 0.456 0.000
C84.4 Peripheral T-cell lymphoma
0.543 0.457 0.000
M11.2 Other chondrocalcinosis
0.543 0.457 0.000
C69.9 Eye, unspecified
0.543 0.457 0.000
E14.5 With peripheral circulatory complications
0.000 0.459 0.541
C74.1 Medulla of adrenal gland
0.541 0.459 0.000
C74.0 Cortex of adrenal gland
0.541 0.459 0.000
C05.9 Palate, unspecified
0.540 0.459 0.000
C05.8 Overlapping lesion of palate
0.540 0.459 0.000
C05.2 Uvula
0.540 0.459 0.000
E24 Cushing's syndrome
0.000 0.462 0.538
J40-J47 Chronic lower respiratory diseases
0.000 0.462 0.538
C65 Malignant neoplasm of renal pelvis
0.538 0.462 0.000
D69.0 Allergic purpura
0.000 0.464 0.536
Chapter X Diseases of the respiratory system
0.000 0.464 0.536
C75.8 Pluriglandular involvement, unspecified
0.535 0.464 0.000
C75.5 Aortic body and other paraganglia
0.535 0.464 0.000
C75.4 Carotid body
0.535 0.464 0.000
C75.3 Pineal gland
0.535 0.464 0.000
C75.2 Craniopharyngeal duct
0.535 0.464 0.000
C75.1 Pituitary gland
0.535 0.464 0.000
C75.0 Parathyroid gland
0.535 0.464 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.535 0.465 0.000
C03.9 Gum, unspecified
0.534 0.466 0.000
C03.0 Upper gum
0.534 0.466 0.000
J33.0 Polyp of nasal cavity
0.000 0.468 0.532
J33 Nasal polyp
0.000 0.468 0.532
T50.8 Diagnostic agents
0.530 0.470 0.000
T50.7 Analeptics and opioid receptor antagonists
0.530 0.470 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.530 0.470 0.000
T50.5 Appetite depressants
0.530 0.470 0.000
T50.4 Drugs affecting uric acid metabolism
0.530 0.470 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.530 0.470 0.000
T50.1 Loop [high-ceiling] diuretics
0.530 0.470 0.000
T50.0 Mineralocorticoids and their antagonists
0.530 0.470 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.530 0.470 0.000
C13.8 Overlapping lesion of hypopharynx
0.529 0.470 0.000
C13.2 Posterior wall of hypopharynx
0.529 0.470 0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.529 0.470 0.000
C13.0 Postcricoid region
0.529 0.470 0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.529 0.471 0.000
M14.6 Neuropathic arthropathy
0.529 0.471 0.000
C84.5 Other and unspecified T-cell lymphomas
0.529 0.471 0.000
C09.8 Overlapping lesion of tonsil
0.529 0.471 0.000
C09.1 Tonsillar pillar (anterior) (posterior)
0.529 0.471 0.000
C09.0 Tonsillar fossa
0.529 0.471 0.000
E21.0 Primary hyperparathyroidism
0.000 0.471 0.529
D69.8 Other specified haemorrhagic conditions
0.000 0.471 0.528
E27.5 Adrenomedullary hyperfunction
0.000 0.472 0.528
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.472 0.528
E27.0 Other adrenocortical overactivity
0.000 0.472 0.528
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.528 0.472 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.528 0.472 0.000
M12.5 Traumatic arthropathy
0.528 0.472 0.000
M12.4 Intermittent hydrarthrosis
0.528 0.472 0.000
M12.3 Palindromic rheumatism
0.528 0.472 0.000
M12.1 Kaschin-Beck disease
0.528 0.472 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.528 0.472 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.527 0.473 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.527 0.473 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.527 0.473 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.527 0.473 0.000
C84.3 Lymphoepithelioid lymphoma
0.527 0.473 0.000
C84.2 T-zone lymphoma
0.527 0.473 0.000
C84.1 Sezary's diease
0.527 0.473 0.000
C84.0 Mycosis fungoides
0.527 0.473 0.000
C10.8 Overlapping lesion of oropharynx
0.526 0.473 0.000
C10.4 Branchial cleft
0.526 0.473 0.000
C10.3 Posterior wall of oropharynx
0.526 0.473 0.000
C10.2 Lateral wall of oropharynx
0.526 0.473 0.000
C10.1 Anterior surface of epiglottis
0.526 0.473 0.000
C10.0 Vallecula
0.526 0.473 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.526 0.474 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.474 0.526
J30-J39 Other diseases of upper respiratory tract
0.000 0.475 0.525
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.524 0.476 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.520 0.480 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.520 0.480 0.000
M14.4 Arthropathy in amyloidosis
0.520 0.480 0.000
M14.3 Lipoid dermatoarthritis
0.520 0.480 0.000
M14.2 Diabetic arthropathy
0.520 0.480 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.520 0.480 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.520 0.480 0.000
M13 Other arthritis
0.520 0.480 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.516 0.484 0.000
C70 Malignant neoplasm of meninges
0.516 0.484 0.000
C05.1 Soft palate
0.515 0.485 0.000
T36 Poisoning by systemic antibiotics
0.515 0.485 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.514 0.486 0.000
M06.18 Adult-onset Still's disease (Other)
0.514 0.486 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.514 0.486 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.514 0.486 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.514 0.486 0.000
M06.14 Adult-onset Still's disease (Hand)
0.514 0.486 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.514 0.486 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.514 0.486 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.514 0.486 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.514 0.486 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.514 0.486 0.000
M06.28 Rheumatoid bursitis (Other)
0.514 0.486 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.514 0.486 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.514 0.486 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.514 0.486 0.000
M06.24 Rheumatoid bursitis (Hand)
0.514 0.486 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.514 0.486 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.514 0.486 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.514 0.486 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.514 0.486 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.514 0.486 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.514 0.486 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.514 0.486 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.514 0.486 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.514 0.486 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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