TreeWAS – Variant ID: rs2891316

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H43.1 Vitreous haemorrhage	0.000	0.601	0.399
H43 Disorders of vitreous body	0.000	0.628	0.372
H43.3 Other vitreous opacities	0.000	0.651	0.349
H43.2 Crystalline deposits in vitreous body	0.000	0.711	0.289
H43-H45 Disorders of vitreous body and globe	0.000	0.724	0.276
H43.9 Disorder of vitreous body, unspecified	0.000	0.732	0.268
H43.0 Vitreous prolapse	0.000	0.733	0.266
H44 Disorders of globe	0.000	0.743	0.257
H44.2 Degenerative myopia	0.000	0.758	0.242
H43.8 Other disorders of vitreous body	0.000	0.759	0.241
H44.1 Other endophthalmitis	0.000	0.797	0.203
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.802	0.198
H44.4 Hypotony of eye	0.000	0.806	0.194
H44.9 Disorder of globe, unspecified	0.000	0.816	0.184
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.816	0.184
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.816	0.184
H44.3 Other degenerative disorders of globe	0.000	0.816	0.184
H44.5 Degenerated conditions of globe	0.000	0.819	0.180
H44.0 Purulent endophthalmitis	0.000	0.825	0.175
H44.8 Other disorders of globe	0.000	0.830	0.170
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.858	0.142
H45.1 Endophthalmitis in diseases classified elsewhere	0.000	0.858	0.142
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.000	0.858	0.142
C77.1 Intrathoracic lymph nodes	0.000	0.994	0.006
G95.2 Cord compression, unspecified	0.000	0.994	0.006
L57.0 Actinic keratosis	0.006	0.994	0.000
K51.9 Ulcerative colitis, unspecified	0.005	0.995	0.000
Z93.3 Colostomy status	0.000	0.995	0.005
G95 Other diseases of spinal cord	0.000	0.995	0.005
S82.30 Fracture of lower end of tibia (closed)	0.005	0.995	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.995	0.005
L57 Skin changes due to chronic exposure to nonionising radiation	0.005	0.995	0.000
L57.4 Cutis laxa senilis	0.004	0.996	0.000
G95.8 Other specified diseases of spinal cord	0.000	0.996	0.004
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.996	0.004
K51.0 Ulcerative (chronic) enterocolitis	0.004	0.996	0.000
G95.1 Vascular myelopathies	0.000	0.996	0.004
G95.9 Disease of spinal cord, unspecified	0.000	0.996	0.004
S64.4 Injury of digital nerve of other finger	0.000	0.996	0.004
K51.4 Pseudopolyposis of colon	0.004	0.996	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.000	0.996	0.004
K51 Ulcerative colitis	0.004	0.996	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.996	0.004
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.996	0.004
D41.0 Kidney	0.004	0.996	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.004	0.996	0.000
G90-G99 Other disorders of the nervous system	0.000	0.996	0.004
L57.5 Actinic granuloma	0.003	0.996	0.000
L57.3 Poikiloderma of Civatte	0.003	0.996	0.000
L57.2 Cutis rhomboidalis nuchae	0.003	0.996	0.000
L57.1 Actinic reticuloid	0.003	0.996	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.003	0.996	0.000
A63.0 Anogenital (venereal) warts	0.000	0.997	0.003
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.000	0.997	0.003
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.000	0.997	0.003
Y52.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
H18.6 Keratoconus	0.003	0.997	0.000
I63.8 Other cerebral infarction	0.000	0.997	0.003
A04.8 Other specified bacterial intestinal infections	0.000	0.997	0.003
K51.8 Other ulcerative colitis	0.003	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.003	0.997	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.000	0.997	0.003
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.997	0.003
K51.1 Ulcerative (chronic) ileocolitis	0.003	0.997	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.003	0.997	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.003	0.997	0.000
E66.8 Other obesity	0.003	0.997	0.000
G91.1 Obstructive hydrocephalus	0.000	0.997	0.003
G95.0 Syringomyelia and syringobulbia	0.000	0.997	0.003
S81.0 Open wound of knee	0.000	0.997	0.003
G94.1 Hydrocephalus in neoplastic disease	0.000	0.997	0.003
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.003	0.997	0.000
G90 Disorders of autonomic nervous system	0.000	0.997	0.003
O73.0 Retained placenta, without haemorrhage	0.000	0.997	0.003
Y53.4 Other laxatives	0.003	0.997	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.997	0.003
K04.6 Periapical abscess with sinus	0.000	0.997	0.003
N85.8 Other specified noninflammatory disorders of uterus	0.000	0.997	0.003
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.003	0.997	0.000
L56.4 Polymorphous light eruption	0.003	0.997	0.000
G92 Toxic encephalopathy	0.000	0.997	0.003
O03.4 Incomplete, without complication	0.000	0.997	0.003
M94.26 Chondromalacia (Lower leg)	0.000	0.997	0.003
G90.2 Horner's syndrome	0.000	0.997	0.003
C73 Malignant neoplasm of thyroid gland	0.003	0.997	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
M45 Ankylosing spondylitis	0.000	0.997	0.003
H57.1 Ocular pain	0.000	0.997	0.003
Z48.9 Surgical follow-up care, unspecified	0.000	0.997	0.003
H18 Other disorders of cornea	0.003	0.997	0.000
G91 Hydrocephalus	0.000	0.997	0.003
E89.0 Postprocedural hypothyroidism	0.003	0.997	0.000
G90.3 Multisystem degeneration	0.000	0.997	0.003
K51.5 Mucosal proctocolitis	0.002	0.997	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.997	0.003
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.997	0.003
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.000	0.997	0.002
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.002
H18.1 Bullous keratopathy	0.002	0.997	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.000	0.997	0.002
L56.3 Solar urticaria	0.002	0.997	0.000
L56.2 Photocontact dermatitis [berloque dermatitis]	0.002	0.997	0.000
L56.1 Drug photoallergic response	0.002	0.997	0.000
L56.0 Drug phototoxic response	0.002	0.997	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.997	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.998	0.002
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.002	0.998	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.998	0.002
H57 Other disorders of eye and adnexa	0.000	0.998	0.002
L58 Radiodermatitis	0.002	0.998	0.000
L55 Sunburn	0.002	0.998	0.000
G90.8 Other disorders of autonomic nervous system	0.000	0.998	0.002
G90.4 Autonomic dysreflexia	0.000	0.998	0.002
G90.1 Familial dysautonomia [Riley-Day]	0.000	0.998	0.002
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.002	0.998	0.000
G97.8 Other postprocedural disorders of nervous system	0.000	0.998	0.002
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
H57.0 Anomalies of pupillary function	0.000	0.998	0.002
H55-H59 Other disorders of eye and adnexa	0.000	0.998	0.002
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.998	0.002
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.998	0.002
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.998	0.002
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
S82.3 Fracture of lower end of tibia	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.000	0.998	0.002
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.000	0.998	0.002
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
H18.2 Other corneal oedema	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.000	0.998	0.002
H18.7 Other corneal deformities	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.000	0.998	0.002
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.998	0.002
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.998	0.002
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.998	0.002
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.998	0.002
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.998	0.002
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.998	0.002
Y46.5 Valproic acid	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.002	0.998	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.998	0.002
G91.3 Posttraumatic hydrocephalus, unspecified	0.000	0.998	0.002
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
K04 Diseases of pulp and periapical tissues	0.000	0.998	0.002
M94.2 Chondromalacia	0.000	0.998	0.002
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.998	0.002
Y40 Systemic antibiotics	0.002	0.998	0.000
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.998	0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.998	0.002
K04.8 Radicular cyst	0.000	0.998	0.002
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
G91.8 Other hydrocephalus	0.000	0.998	0.002
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified	0.002	0.998	0.000
L59.0 Erythema ab igne [dermatitis ab igne]	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
L55.9 Sunburn, unspecified	0.002	0.998	0.000
L55.8 Other sunburn	0.002	0.998	0.000
L55.2 Sunburn of third degree	0.002	0.998	0.000
L55.1 Sunburn of second degree	0.002	0.998	0.000
L55.0 Sunburn of first degree	0.002	0.998	0.000
L58.9 Radiodermatitis, unspecified	0.002	0.998	0.000
L58.1 Chronic radiodermatitis	0.002	0.998	0.000
L58.0 Acute radiodermatitis	0.002	0.998	0.000
G93.0 Cerebral cysts	0.000	0.998	0.002
T83.3 Mechanical complication of intra-uterine contraceptive device	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y40.0 Penicillins	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
G96 Other disorders of central nervous system	0.001	0.998	0.001
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
C80.9 Malignant neoplasm, unspecified	0.000	0.998	0.002
H59.0 Vitreous syndrome following cataract surgery	0.000	0.998	0.002
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.998	0.002
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.998	0.002
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.998	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y83.5 Amputation of limb(s)	0.000	0.998	0.002
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S32.50 Fracture of pubis (closed)	0.000	0.998	0.002
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.000	0.998	0.002
H58.1 Visual disturbances in diseases classified elsewhere	0.000	0.998	0.002
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.000	0.998	0.002
I31.9 Disease of pericardium, unspecified	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
G91.2 Normal-pressure hydrocephalus	0.000	0.998	0.002
H18.8 Other specified disorders of cornea	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.000	0.998	0.002
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
K04.0 Pulpitis	0.000	0.998	0.002
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.002	0.998	0.000
E06.3 Autoimmune thyroiditis	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.002	0.998	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.000	0.998	0.002
K04.3 Abnormal hard tissue formation in pulp	0.000	0.998	0.002
K04.2 Pulp degeneration	0.000	0.998	0.002
K04.1 Necrosis of pulp	0.000	0.998	0.002
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
M94.29 Chondromalacia (Site unspecified)	0.000	0.998	0.002
M94.28 Chondromalacia (Other)	0.000	0.998	0.002
M94.27 Chondromalacia (Ankle and foot)	0.000	0.998	0.002
M94.25 Chondromalacia (Pelvic region and thigh)	0.000	0.998	0.002
M94.24 Chondromalacia (Hand)	0.000	0.998	0.002
M94.23 Chondromalacia (Forearm)	0.000	0.998	0.002
M94.22 Chondromalacia (Upper arm)	0.000	0.998	0.002
M94.21 Chondromalacia (Shoulder region)	0.000	0.998	0.002
M94.20 Chondromalacia (Multiple sites)	0.000	0.998	0.002
F43.2 Adjustment disorders	0.000	0.998	0.002
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
G91.0 Communicating hydrocephalus	0.000	0.998	0.002
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
Z43.3 Attention to colostomy	0.000	0.998	0.002
Y58 Bacterial vaccines	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.998	0.002
Z37.2 Twins, both liveborn	0.000	0.998	0.002
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.002	0.998	0.000
W18.3 Sports and athletics area	0.000	0.998	0.002
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
G93.5 Compression of brain	0.000	0.998	0.002
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y88 Sequelae of surgical and medical care as external cause	0.002	0.998	0.000
K04.5 Chronic apical periodontitis	0.000	0.998	0.002
M48.02 Spinal stenosis (Cervical region)	0.000	0.998	0.002
G96.9 Disorder of central nervous system, unspecified	0.001	0.998	0.001
H57.8 Other specified disorders of eye and adnexa	0.000	0.998	0.002
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.001	0.998	0.000
A63.8 Other specified predominantly sexually transmitted diseases	0.000	0.998	0.001
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
G93 Other disorders of brain	0.000	0.998	0.002
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.998	0.002
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Z47.8 Other specified orthopaedic follow-up care	0.000	0.998	0.002
M94 Other disorders of cartilage	0.000	0.998	0.002
M05.29 Rheumatoid vasculitis (Site unspecified)	0.002	0.998	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.998	0.002
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.998	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.998	0.002
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.998	0.002
I45.5 Other specified heart block	0.002	0.998	0.000
M94.8 Other specified disorders of cartilage	0.000	0.998	0.002
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.998	0.002
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
G96.8 Other specified disorders of central nervous system	0.001	0.998	0.001
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.998	0.002
T83.0 Mechanical complication of urinary (indwelling) catheter	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.001	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.998	0.000
Y59.2 Protozoal vaccines	0.001	0.998	0.000
Y59.1 Rickettsial vaccines	0.001	0.998	0.000
Y59.0 Viral vaccines	0.001	0.998	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
G96.0 Cerebrospinal fluid leak	0.001	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
Y55.5 Anticommon cold drugs	0.001	0.998	0.000
Y55.4 Expectorants	0.001	0.998	0.000
Y55.3 Antitussives	0.001	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
Y55.0 Oxytocic drugs	0.001	0.998	0.000
Y58.0 BCG vaccine	0.001	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.001	0.998	0.001
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.002	0.998	0.000
M14.6 Neuropathic arthropathy	0.000	0.998	0.002
M94.9 Disorder of cartilage, unspecified	0.000	0.998	0.001
Y44.9 Other and unspecified agents affecting blood constituents	0.001	0.998	0.000
Y44.7 Plasma substitutes	0.001	0.998	0.000
Y44.6 Natural blood and blood products	0.001	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.001	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.001	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.001	0.998	0.000
M71.12 Other infective bursitis (Upper arm)	0.002	0.998	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.002	0.998	0.000
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.001	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.001	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.001	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.001	0.998	0.000
Y58.5 Diphtheria vaccine	0.001	0.998	0.000
Y58.4 Tetanus vaccine	0.001	0.998	0.000
Y58.3 Plague vaccine	0.001	0.998	0.000
Y58.2 Cholera vaccine	0.001	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.001	0.998	0.000
M71.16 Other infective bursitis (Lower leg)	0.001	0.998	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.001	0.998	0.000
Y44.5 Thrombolytic drugs	0.001	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.001	0.998	0.000
Y50.8 Other central nervous system stimulants	0.001	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.998	0.000
Y50.1 Opioid receptor antagonists	0.001	0.998	0.000
Y50.0 Analeptics	0.001	0.998	0.000
H21 Other disorders of iris and ciliary body	0.001	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.001	0.998	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.000	0.998	0.001
O73 Retained placenta and membranes, without haemorrhage	0.000	0.998	0.002
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.998	0.000
Y47.4 Bromine compounds	0.001	0.998	0.000
Y47.3 Paraldehyde	0.001	0.998	0.000
Y47.2 Chloral derivatives	0.001	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.998	0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.001	0.998	0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.001	0.998	0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.001	0.998	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.001	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.000	0.998	0.001
G93.2 Benign intracranial hypertension	0.000	0.998	0.001
H18.4 Corneal degeneration	0.001	0.998	0.000
M47.8 Other spondylosis	0.000	0.998	0.002
G93.7 Reye's syndrome	0.000	0.998	0.001
M05.2 Rheumatoid vasculitis	0.001	0.998	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.000	0.998	0.001
Y44.2 Anticoagulants	0.001	0.998	0.000
M43.02 Spondylolysis (Cervical region)	0.000	0.999	0.001
M94.3 Chondrolysis	0.000	0.999	0.001
M94.1 Relapsing polychondritis	0.000	0.999	0.001
M94.0 Chondrocostal junction syndrome [Tietze]	0.000	0.999	0.001
Y56.9 Topical agent, unspecified	0.001	0.999	0.000
Y56.8 Other topical agents	0.001	0.999	0.000
Y56.7 Dental drugs, topically applied	0.001	0.999	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.999	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.999	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.999	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.999	0.000
Y56.2 Local astringents and local detergents	0.001	0.999	0.000
Y56.1 Antipruritics	0.001	0.999	0.000
S64 Injury of nerves at wrist and hand level	0.000	0.999	0.001
K65.9 Peritonitis, unspecified	0.001	0.999	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.999	0.000
Y47.1 Benzodiazepines	0.001	0.999	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.000	0.999	0.001
M94.84 Other specified disorders of cartilage (Hand)	0.000	0.999	0.001
M94.83 Other specified disorders of cartilage (Forearm)	0.000	0.999	0.001
M94.82 Other specified disorders of cartilage (Upper arm)	0.000	0.999	0.001
M94.81 Other specified disorders of cartilage (Shoulder region)	0.000	0.999	0.001
M94.80 Other specified disorders of cartilage (Multiple sites)	0.000	0.999	0.001
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.999	0.001
R23.8 Other and unspecified skin changes	0.001	0.999	0.000
Y49.2 Other and unspecified antidepressants	0.001	0.999	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
Q39.4 Oesophageal web	0.001	0.999	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.001	0.999	0.000
Y57.7 Vitamins, not elsewhere classified	0.001	0.999	0.000
Y57.4 Pharmaceutical excipients	0.001	0.999	0.000
Y57.3 Alcohol deterrents	0.001	0.999	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.001	0.999	0.000
Y57.1 Lipotropic drugs	0.001	0.999	0.000
Y57.0 Appetite depressants [anorectics]	0.001	0.999	0.000
M94.99 Disorder of cartilage, unspecified (Site unspecified)	0.000	0.999	0.001
M94.98 Disorder of cartilage, unspecified (Other)	0.000	0.999	0.001
M94.97 Disorder of cartilage, unspecified (Ankle and foot)	0.000	0.999	0.001
M94.95 Disorder of cartilage, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M94.94 Disorder of cartilage, unspecified (Hand)	0.000	0.999	0.001
M94.93 Disorder of cartilage, unspecified (Forearm)	0.000	0.999	0.001
M94.92 Disorder of cartilage, unspecified (Upper arm)	0.000	0.999	0.001
M94.91 Disorder of cartilage, unspecified (Shoulder region)	0.000	0.999	0.001
M94.90 Disorder of cartilage, unspecified (Multiple sites)	0.000	0.999	0.001
M21.1 Varus deformity, not elsewhere classified	0.000	0.999	0.001
S10.9 Superficial injury of neck, part unspecified	0.000	0.999	0.001
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.999	0.001
Z35.5 Supervision of elderly primigravida	0.001	0.999	0.000
B37.8 Candidiasis of other sites	0.001	0.999	0.000
Y40.8 Other systemic antibiotics	0.001	0.999	0.000
Y48.5 Therapeutic gases	0.001	0.999	0.000
Y48.4 Anaesthetic, unspecified	0.001	0.999	0.000
Y48.1 Parenteral anaesthetics	0.001	0.999	0.000
Y48.0 Inhaled anaesthetics	0.001	0.999	0.000
M62.88 Other specified disorders of muscle (Other)	0.001	0.999	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.999	0.001
A41.8 Other specified septicaemia	0.001	0.999	0.000
H21.4 Pupillary membranes	0.001	0.999	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.001	0.999	0.000
H21.2 Degeneration of iris and ciliary body	0.001	0.999	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.001	0.999	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.001	0.999	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.001	0.999	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.999	0.001
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.999	0.001
T83.2 Mechanical complication of graft of urinary organ	0.001	0.999	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.001	0.999	0.000
Y54.9 Mineral salts, not elsewhere classified	0.001	0.999	0.000
Y54.8 Agents affecting uric acid metabolism	0.001	0.999	0.000
Y54.7 Agents affecting calcification	0.001	0.999	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.001	0.999	0.000
Y54.4 Loop [high-ceiling] diuretics	0.001	0.999	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.001	0.999	0.000
Y54.0 Mineralocorticoids	0.001	0.999	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.001	0.999	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.000	0.999	0.001
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M94.88 Other specified disorders of cartilage (Other)	0.000	0.999	0.001
C74.9 Adrenal gland, unspecified	0.001	0.999	0.000
G93.4 Encephalopathy, unspecified	0.000	0.999	0.001
Q44.6 Cystic disease of liver	0.001	0.999	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.001	0.999	0.000
C74 Malignant neoplasm of adrenal gland	0.001	0.999	0.000
M05.28 Rheumatoid vasculitis (Other)	0.001	0.999	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.001	0.999	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.001	0.999	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.001	0.999	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.001	0.999	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.001	0.999	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.001	0.999	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.001	0.999	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.001	0.999	0.000
M94.09 Chondrocostal junction syndrome [Tietze]-Site unspec	0.000	0.999	0.001
M94.08 Chondrocostal junction syndrome [Tietze]-Other	0.000	0.999	0.001
M94.07 Chondrocostal junction syndrome [Tietze]-Ankle/foot	0.000	0.999	0.001
M94.06 Chondrocostal junction syndrome [Tietze]-Lower leg	0.000	0.999	0.001
M94.05 Chondrocostal junction syndrome [Tietze]-Pelvic/thigh	0.000	0.999	0.001
M94.04 Chondrocostal junction syndrome [Tietze]-Hand	0.000	0.999	0.001
M94.03 Chondrocostal junction syndrome [Tietze]-Forearm	0.000	0.999	0.001
M94.02 Chondrocostal junction syndrome [Tietze]-Upper arm	0.000	0.999	0.001
M94.01 Chondrocostal junction syndrome [Tietze]-Shldr region	0.000	0.999	0.001
M94.00 Chondrocostal junction syndrome [Tietze]-Mult sites	0.000	0.999	0.001
M94.19 Relapsing polychondritis (Site unspecified)	0.000	0.999	0.001
M94.18 Relapsing polychondritis (Other)	0.000	0.999	0.001
M94.17 Relapsing polychondritis (Ankle and foot)	0.000	0.999	0.001
M94.16 Relapsing polychondritis (Lower leg)	0.000	0.999	0.001
M94.15 Relapsing polychondritis (Pelvic region and thigh)	0.000	0.999	0.001
M94.14 Relapsing polychondritis (Hand)	0.000	0.999	0.001
M94.13 Relapsing polychondritis (Forearm)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations