TreeWAS – Variant ID: rs28998802

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H35.8 Other specified retinal disorders	0.000	0.954	0.046
H35 Other retinal disorders	0.000	0.989	0.011
H35.4 Peripheral retinal degeneration	0.000	0.990	0.010
L03.0 Cellulitis of finger and toe	0.000	0.990	0.010
H35.5 Hereditary retinal dystrophy	0.000	0.991	0.009
M22.4 Chondromalacia patellae	0.009	0.991	0.000
H35.1 Retinopathy of prematurity	0.000	0.992	0.008
T90.9 Sequelae of unspecified injury of head	0.008	0.992	0.000
E16.2 Hypoglycaemia, unspecified	0.008	0.992	0.000
H35.9 Retinal disorder, unspecified	0.000	0.992	0.007
D32.0 Cerebral meninges	0.007	0.993	0.000
H35.6 Retinal haemorrhage	0.000	0.993	0.007
T90 Sequelae of injuries of head	0.007	0.993	0.000
H35.2 Other proliferative retinopathy	0.000	0.993	0.007
Q24 Other congenital malformations of heart	0.007	0.993	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.007	0.993	0.000
T90.5 Sequelae of intracranial injury	0.007	0.993	0.000
H34.8 Other retinal vascular occlusions	0.000	0.993	0.007
T90.2 Sequelae of fracture of skull and facial bones	0.007	0.993	0.000
H34 Retinal vascular occlusions	0.000	0.993	0.007
M22.3 Other derangements of patella	0.007	0.993	0.000
H30-H36 Disorders of choroid and retina	0.000	0.994	0.006
H35.7 Separation of retinal layers	0.000	0.994	0.006
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.994	0.006
Q24.5 Malformation of coronary vessels	0.006	0.994	0.000
M22 Disorders of patella	0.006	0.994	0.000
Q21 Congenital malformations of cardiac septa	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
Q89.2 Congenital malformations of other endocrine glands	0.006	0.994	0.000
Q24.8 Other specified congenital malformations of heart	0.006	0.994	0.000
H33.3 Retinal breaks without detachment	0.000	0.994	0.006
H34.2 Other retinal artery occlusions	0.000	0.994	0.006
T90.8 Sequelae of other specified injuries of head	0.006	0.994	0.000
Q21.3 Tetralogy of Fallot	0.006	0.994	0.000
T90.4 Sequelae of injury of eye and orbit	0.005	0.994	0.000
Q21.1 Atrial septal defect	0.005	0.995	0.000
T90.3 Sequelae of injury of cranial nerves	0.005	0.995	0.000
T90.1 Sequelae of open wound of head	0.005	0.995	0.000
T90.0 Sequelae of superficial injury of head	0.005	0.995	0.000
E16 Other disorders of pancreatic internal secretion	0.005	0.995	0.000
Q24.6 Congenital heart block	0.005	0.995	0.000
Q24.4 Congenital subaortic stenosis	0.005	0.995	0.000
Q24.3 Pulmonary infundibular stenosis	0.005	0.995	0.000
Q24.2 Cor triatriatum	0.005	0.995	0.000
Q24.1 Levocardia	0.005	0.995	0.000
Q24.0 Dextrocardia	0.005	0.995	0.000
M22.8 Other disorders of patella	0.005	0.995	0.000
G62.9 Polyneuropathy, unspecified	0.005	0.995	0.000
Q89 Other congenital malformations, not elsewhere classified	0.005	0.995	0.000
M22.9 Disorder of patella, unspecified	0.005	0.995	0.000
H34.9 Retinal vascular occlusion, unspecified	0.000	0.995	0.005
H34.0 Transient retinal artery occlusion	0.000	0.995	0.005
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.995	0.005
H30 Chorioretinal inflammation	0.000	0.995	0.005
Q21.0 Ventricular septal defect	0.005	0.995	0.000
H33 Retinal detachments and breaks	0.000	0.995	0.005
H61.9 Disorder of external ear, unspecified	0.005	0.995	0.000
M22.1 Recurrent subluxation of patella	0.005	0.995	0.000
M23.8 Other internal derangements of knee	0.000	0.995	0.005
J32.9 Chronic sinusitis, unspecified	0.000	0.995	0.005
Q21.9 Congenital malformation of cardiac septum, unspecified	0.005	0.995	0.000
Q21.8 Other congenital malformations of cardiac septa	0.005	0.995	0.000
Q21.4 Aortopulmonary septal defect	0.005	0.995	0.000
Q21.2 Atrioventricular septal defect	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.005	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.005	0.995	0.000
H61 Other disorders of external ear	0.005	0.995	0.000
Q28 Other congenital malformations of circulatory system	0.005	0.995	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.995	0.005
E16.0 Drug-induced hypoglycaemia without coma	0.004	0.995	0.000
H31 Other disorders of choroid	0.000	0.995	0.004
Q80-Q89 Other congenital malformations	0.004	0.995	0.000
H61.2 Impacted cerumen	0.004	0.996	0.000
E16.1 Other hypoglycaemia	0.004	0.996	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.996	0.004
M22.0 Recurrent dislocation of patella	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
Q60-Q64 Congenital malformations of the urinary system	0.004	0.996	0.000
E87.7 Fluid overload	0.004	0.996	0.000
H34.1 Central retinal artery occlusion	0.000	0.996	0.004
D32 Benign neoplasm of meninges	0.004	0.996	0.000
L05.0 Pilonidal cyst with abscess	0.004	0.996	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.004	0.996	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.004	0.996	0.000
E16.4 Abnormal secretion of gastrin	0.004	0.996	0.000
E16.3 Increased secretion of glucagon	0.004	0.996	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.996	0.004
D32.9 Meninges, unspecified	0.004	0.996	0.000
Q43.8 Other specified congenital malformations of intestine	0.004	0.996	0.000
Q25.4 Other congenital malformations of aorta	0.004	0.996	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.004	0.996	0.000
Q25.6 Stenosis of pulmonary artery	0.004	0.996	0.000
Q89.9 Congenital malformation, unspecified	0.004	0.996	0.000
Q89.8 Other specified congenital malformations	0.004	0.996	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.004	0.996	0.000
Q89.4 Conjoined twins	0.004	0.996	0.000
Q89.3 Situs inversus	0.004	0.996	0.000
Q89.1 Congenital malformations of adrenal gland	0.004	0.996	0.000
Q89.0 Congenital malformations of spleen	0.004	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.004	0.996	0.000
Q27 Other congenital malformations of peripheral vascular system	0.004	0.996	0.000
I49.8 Other specified cardiac arrhythmias	0.000	0.996	0.004
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
H35.0 Background retinopathy and retinal vascular changes	0.000	0.996	0.004
Q28.0 Arteriovenous malformation of precerebral vessels	0.004	0.996	0.000
H61.0 Perichondritis of external ear	0.004	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
H30.9 Chorioretinal inflammation, unspecified	0.000	0.996	0.004
H30.8 Other chorioretinal inflammations	0.000	0.996	0.004
H30.2 Posterior cyclitis	0.000	0.996	0.004
H30.1 Disseminated chorioretinal inflammation	0.000	0.996	0.004
H30.0 Focal chorioretinal inflammation	0.000	0.996	0.004
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.000	0.996	0.004
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.996	0.000
Q25.3 Stenosis of aorta	0.004	0.996	0.000
Q25.2 Atresia of aorta	0.004	0.996	0.000
Q25.0 Patent ductus arteriosus	0.004	0.996	0.000
E04.9 Non-toxic goitre, unspecified	0.004	0.996	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.004	0.996	0.000
H61.3 Acquired stenosis of external ear canal	0.004	0.996	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.003	0.996	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.996	0.004
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.996	0.004
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.996	0.004
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.996	0.004
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.996	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.996	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.996	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.996	0.000
Q20.4 Double inlet ventricle	0.003	0.996	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.996	0.000
Q20.2 Double outlet left ventricle	0.003	0.996	0.000
Q20.1 Double outlet right ventricle	0.003	0.996	0.000
Q20.0 Common arterial trunk	0.003	0.996	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.996	0.000
Q22.5 Ebstein's anomaly	0.003	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.996	0.000
Q22.0 Pulmonary valve atresia	0.003	0.996	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.996	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.996	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.996	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.996	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.996	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.996	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.996	0.000
Q26.1 Persistent left superior vena cava	0.003	0.996	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.996	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.004	0.996	0.000
Q45 Other congenital malformations of digestive system	0.003	0.996	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.996	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.996	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.996	0.000
H31.8 Other specified disorders of choroid	0.000	0.996	0.003
Q23 Congenital malformations of aortic and mitral valves	0.003	0.996	0.000
Q61 Cystic kidney disease	0.004	0.996	0.000
H33.2 Serous retinal detachment	0.000	0.996	0.004
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.996	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.996	0.000
Q28.3 Other malformations of cerebral vessels	0.003	0.996	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.996	0.000
H36 Retinal disorders in diseases classified elsewhere	0.000	0.996	0.004
H33.4 Traction detachment of retina	0.000	0.996	0.003
Q25.1 Coarctation of aorta	0.003	0.996	0.000
H61.8 Other specified disorders of external ear	0.003	0.996	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.003	0.996	0.000
Q84 Other congenital malformations of integument	0.003	0.996	0.000
Q81 Epidermolysis bullosa	0.003	0.996	0.000
Q80 Congenital ichthyosis	0.003	0.996	0.000
H31.9 Disorder of choroid, unspecified	0.000	0.996	0.003
H31.4 Choroidal detachment	0.000	0.996	0.003
H31.3 Choroidal haemorrhage and rupture	0.000	0.996	0.003
H31.2 Hereditary choroidal dystrophy	0.000	0.996	0.003
Q60.0 Renal agenesis, unilateral	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.997	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.997	0.003
H60-H62 Diseases of external ear	0.003	0.997	0.000
G93.8 Other specified disorders of brain	0.003	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
Q44.6 Cystic disease of liver	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
Q43.7 Persistent cloaca	0.003	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.003	0.997	0.000
Q43.5 Ectopic anus	0.003	0.997	0.000
Q43.4 Duplication of intestine	0.003	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.003	0.997	0.000
Q43.1 Hirschsprung's disease	0.003	0.997	0.000
H60 Otitis externa	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
H61.1 Non-infective disorders of pinna	0.003	0.997	0.000
H31.0 Chorioretinal scars	0.000	0.997	0.003
Q61.0 Congenital single renal cyst	0.003	0.997	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.003	0.997	0.000
Q43.3 Congenital malformations of intestinal fixation	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
H33.1 Retinoschisis and retinal cysts	0.000	0.997	0.003
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.997	0.003
E04.1 Non-toxic single thyroid nodule	0.003	0.997	0.000
Q61.4 Renal dysplasia	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
H60.2 Malignant otitis externa	0.003	0.997	0.000
Q65.8 Other congenital deformities of hip	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
H31.1 Choroidal degeneration	0.000	0.997	0.003
Q28.2 Arteriovenous malformation of cerebral vessels	0.003	0.997	0.000
Q44.7 Other congenital malformations of liver	0.003	0.997	0.000
Q44.5 Other congenital malformations of bile ducts	0.003	0.997	0.000
Q44.4 Choledochal cyst	0.003	0.997	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.003	0.997	0.000
Q44.2 Atresia of bile ducts	0.003	0.997	0.000
Q44.1 Other congenital malformations of gallbladder	0.003	0.997	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.003	0.997	0.000
Q61.9 Cystic kidney disease, unspecified	0.003	0.997	0.000
E04 Other non-toxic goitre	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
Q11.1 Other anophthalmos	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
H33.5 Other retinal detachments	0.000	0.997	0.003
H60.9 Otitis externa, unspecified	0.003	0.997	0.000
Q83 Congenital malformations of breast	0.003	0.997	0.000
H60.8 Other otitis externa	0.003	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
Q38.8 Other congenital malformations of pharynx	0.003	0.997	0.000
Q38.6 Other congenital malformations of mouth	0.003	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.003	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.003	0.997	0.000
Q38.2 Macroglossia	0.003	0.997	0.000
Q38.1 Ankyloglossia	0.003	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.003	0.997	0.000
Q63 Other congenital malformations of kidney	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q96 Turner's syndrome	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q74.1 Congenital malformation of knee	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
Q31 Congenital malformations of larynx	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
Q36 Cleft lip	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
D61.9 Aplastic anaemia, unspecified	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.003	0.997	0.000
Q60.6 Potter's syndrome	0.003	0.997	0.000
Q60.5 Renal hypoplasia, unspecified	0.003	0.997	0.000
Q60.4 Renal hypoplasia, bilateral	0.003	0.997	0.000
Q60.3 Renal hypoplasia, unilateral	0.003	0.997	0.000
Q60.1 Renal agenesis, bilateral	0.003	0.997	0.000
M22.2 Patellofemoral disorders	0.003	0.997	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.003	0.997	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.003	0.997	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
Q40.1 Congenital hiatus hernia	0.003	0.997	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.003	0.997	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.003	0.997	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.003	0.997	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.003	0.997	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.003	0.997	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.003	0.997	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.003	0.997	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.003	0.997	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.003	0.997	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.003	0.997	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.003	0.997	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.003	0.997	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.003	0.997	0.000
Q45.8 Other specified congenital malformations of digestive system	0.003	0.997	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.003	0.997	0.000
Q45.2 Congenital pancreatic cyst	0.003	0.997	0.000
Q45.1 Annular pancreas	0.003	0.997	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.003	0.997	0.000
K86.1 Other chronic pancreatitis	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.003	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.997	0.003
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
D32.1 Spinal meninges	0.003	0.997	0.000
E83.1 Disorders of iron metabolism	0.000	0.997	0.003
Q23.0 Congenital stenosis of aortic valve	0.003	0.997	0.000
Q43.0 Meckel's diverticulum	0.003	0.997	0.000
Q80.9 Congenital ichthyosis, unspecified	0.003	0.997	0.000
Q80.8 Other congenital ichthyosis	0.003	0.997	0.000
Q80.4 Harlequin foetus	0.003	0.997	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.003	0.997	0.000
Q80.2 Lamellar ichthyosis	0.003	0.997	0.000
Q80.1 X-linked ichthyosis	0.003	0.997	0.000
Q80.0 Ichthyosis vulgaris	0.003	0.997	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.003	0.997	0.000
Q81.8 Other epidermolysis bullosa	0.003	0.997	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.003	0.997	0.000
Q81.1 Epidermolysis bullosa letalis	0.003	0.997	0.000
Q81.0 Epidermolysis bullosa simplex	0.003	0.997	0.000
Q84.9 Congenital malformation of integument, unspecified	0.003	0.997	0.000
Q84.8 Other specified congenital malformations of integument	0.003	0.997	0.000
Q84.6 Other congenital malformations of nails	0.003	0.997	0.000
Q84.5 Enlarged and hypertrophic nails	0.003	0.997	0.000
Q84.4 Congenital leukonychia	0.003	0.997	0.000
Q84.3 Anonychia	0.003	0.997	0.000
Q84.2 Other congenital malformations of hair	0.003	0.997	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.003	0.997	0.000
Q84.0 Congenital alopecia	0.003	0.997	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.003	0.997	0.000
Q86.2 Dysmorphism due to warfarin	0.003	0.997	0.000
Q86.1 Foetal hydantoin syndrome	0.003	0.997	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.003	0.997	0.000
E04.0 Non-toxic diffuse goitre	0.003	0.997	0.000
Q82 Other congenital malformations of skin	0.003	0.997	0.000
Q63.2 Ectopic kidney	0.003	0.997	0.000
Q65.9 Congenital deformity of hip, unspecified	0.003	0.997	0.000
Q65.6 Unstable hip	0.003	0.997	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.003	0.997	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.003	0.997	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.003	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.003	0.997	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.003	0.997	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.003	0.997	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.003	0.997	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.003	0.997	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.003	0.997	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.003	0.997	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.003	0.997	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.997	0.003
H60.4 Cholesteatoma of external ear	0.003	0.997	0.000
Q61.5 Medullary cystic kidney	0.003	0.997	0.000
S22.30 Fracture of rib (closed)	0.003	0.997	0.000
Q60.2 Renal agenesis, unspecified	0.003	0.997	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.003	0.997	0.000
Q85.1 Tuberous sclerosis	0.003	0.997	0.000
H60.0 Abscess of external ear	0.003	0.997	0.000
Q11.3 Macrophthalmos	0.002	0.997	0.000
Q11.2 Microphthalmos	0.002	0.997	0.000
Q11.0 Cystic eyeball	0.002	0.997	0.000
Q15.0 Congenital glaucoma	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.997	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.997	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.997	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.997	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.997	0.000
Q04 Other congenital malformations of brain	0.002	0.997	0.000
Q03 Congenital hydrocephalus	0.002	0.997	0.000
Q01 Encephalocele	0.002	0.997	0.000
Q00 Anencephaly and similar malformations	0.002	0.997	0.000
Q02 Microcephaly	0.002	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
Q85.9 Phakomatosis, unspecified	0.002	0.997	0.000
H60.1 Cellulitis of external ear	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.002	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.002	0.997	0.000
Q62.6 Malposition of ureter	0.002	0.997	0.000
Q62.4 Agenesis of ureter	0.002	0.997	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.002	0.997	0.000
Q62.2 Congenital megaloureter	0.002	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.002	0.997	0.000
Q62.0 Congenital hydronephrosis	0.002	0.997	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.003	0.997	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.997	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.997	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.997	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.997	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.997	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.997	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.997	0.000
Q62.5 Duplication of ureter	0.002	0.997	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.997	0.000
Q64.4 Malformation of urachus	0.002	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.997	0.000
Q64.0 Epispadias	0.002	0.997	0.000
Q12 Congenital lens malformations	0.002	0.997	0.000
D61.0 Constitutional aplastic anaemia	0.003	0.997	0.000
Q17.5 Prominent ear	0.002	0.997	0.000
Q53 Undescended testicle	0.002	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.997	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.003	0.997	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
Q15.9 Congenital malformation of eye, unspecified	0.002	0.997	0.000
Q15.8 Other specified congenital malformations of eye	0.002	0.997	0.000
H60.3 Other infective otitis externa	0.002	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.997	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.997	0.000
Q17.9 Congenital malformation of ear, unspecified	0.002	0.997	0.000
Q17.8 Other specified congenital malformations of ear	0.002	0.997	0.000
Q17.4 Misplaced ear	0.002	0.997	0.000
Q17.3 Other misshapen ear	0.002	0.997	0.000
Q17.2 Microtia	0.002	0.997	0.000
Q17.1 Macrotia	0.002	0.997	0.000
Q17.0 Accessory auricle	0.002	0.997	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.997	0.000
Q79.4 Prune belly syndrome	0.002	0.997	0.000
Q79.3 Gastroschisis	0.002	0.997	0.000
Q79.2 Exomphalos	0.002	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.002	0.997	0.000
Q87.4 Marfan's syndrome	0.002	0.997	0.000
Q39.6 Diverticulum of oesophagus	0.002	0.997	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.997	0.000
E04.8 Other specified non-toxic goitre	0.002	0.997	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.002	0.997	0.000
Q67.8 Other congenital deformities of chest	0.002	0.997	0.000
Q67.7 Pectus carinatum	0.002	0.997	0.000
Q67.6 Pectus excavatum	0.002	0.997	0.000
Q67.5 Congenital deformity of spine	0.002	0.997	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.997	0.000
Q67.3 Plagiocephaly	0.002	0.997	0.000
Q67.2 Dolichocephaly	0.002	0.997	0.000
Q67.1 Compression facies	0.002	0.997	0.000
Q67.0 Facial asymmetry	0.002	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.997	0.000
Q68.3 Congenital bowing of femur	0.002	0.997	0.000
Q68.2 Congenital deformity of knee	0.002	0.997	0.000
Q68.1 Congenital deformity of hand	0.002	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.997	0.000
Q69.9 Polydactyly, unspecified	0.002	0.997	0.000
Q69.2 Accessory toe(s)	0.002	0.997	0.000
Q69.1 Accessory thumb(s)	0.002	0.997	0.000
Q69.0 Accessory finger(s)	0.002	0.997	0.000
Q70.9 Syndactyly, unspecified	0.002	0.997	0.000
Q70.4 Polysyndactyly	0.002	0.997	0.000
Q70.3 Webbed toes	0.002	0.997	0.000
Q70.2 Fused toes	0.002	0.997	0.000
Q70.1 Webbed fingers	0.002	0.997	0.000
Q70.0 Fused fingers	0.002	0.997	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.997	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.997	0.000
Q71.6 Lobster-claw hand	0.002	0.997	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.997	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.997	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.997	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.997	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.997	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.997	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.997	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations