TreeWAS – Variant ID: rs2903492

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E66.9 Obesity, unspecified	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
E66 Obesity	0.999	0.001	0.000
E11.9 Without complications	0.999	0.001	0.000
E11.4 With neurological complications	0.995	0.005	0.000
E66.8 Other obesity	0.991	0.009	0.000
E10-E14 Diabetes mellitus	0.979	0.021	0.000
E65-E68 Obesity and other hyperalimentation	0.971	0.029	0.000
E11.2 With renal complications	0.958	0.042	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.935	0.065	0.000
E11.3 With ophthalmic complications	0.909	0.091	0.000
E10 Insulin-dependent diabetes mellitus	0.847	0.153	0.000
E11.5 With peripheral circulatory complications	0.835	0.165	0.000
E14 Unspecified diabetes mellitus	0.831	0.169	0.000
E65 Localised adiposity	0.820	0.180	0.000
E66.0 Obesity due to excess calories	0.797	0.203	0.000
E11.8 With unspecified complications	0.797	0.203	0.000
E10.9 Without complications	0.766	0.234	0.000
E11.7 With multiple complications	0.753	0.247	0.000
E14.3 With ophthalmic complications	0.729	0.271	0.000
E66.1 Drug-induced obesity	0.716	0.284	0.000
E12 Malnutrition-related diabetes mellitus	0.702	0.298	0.000
E67 Other hyperalimentation	0.696	0.304	0.000
E68 Sequelae of hyperalimentation	0.696	0.304	0.000
E10.0 With coma	0.673	0.327	0.000
E10.8 With unspecified complications	0.672	0.328	0.000
E11.1 With ketoacidosis	0.672	0.328	0.000
E10.4 With neurological complications	0.668	0.332	0.000
E50-E64 Other nutritional deficiencies	0.668	0.332	0.000
E10.7 With multiple complications	0.665	0.335	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.661	0.339	0.000
E11.6 With other specified complications	0.647	0.353	0.000
E14.6 With other specified complications	0.645	0.355	0.000
E10.2 With renal complications	0.639	0.360	0.000
E14.1 With ketoacidosis	0.637	0.363	0.000
E14.8 With unspecified complications	0.622	0.378	0.000
E61 Deficiency of other nutrient elements	0.620	0.380	0.000
E14.5 With peripheral circulatory complications	0.614	0.386	0.000
E13 Other specified diabetes mellitus	0.608	0.392	0.000
E14.7 With multiple complications	0.596	0.404	0.000
E11.0 With coma	0.593	0.407	0.000
E61.1 Iron deficiency	0.589	0.411	0.000
E10.5 With peripheral circulatory complications	0.588	0.411	0.000
E10.6 With other specified complications	0.579	0.421	0.000
E14.0 With coma	0.578	0.422	0.000
E14.2 Withrenal complications	0.576	0.424	0.000
E14.4 With neurological complications	0.530	0.469	0.000
E14.9 Without complications	0.530	0.470	0.000
E40-E46 Malnutrition	0.513	0.487	0.000
E58 Dietary calcium deficiency	0.513	0.487	0.000
E12.9 Without complications	0.503	0.497	0.000
E12.8 With unspecified complications	0.503	0.497	0.000
E12.7 With multiple complications	0.503	0.497	0.000
E12.6 With other specified complications	0.503	0.497	0.000
E12.5 With peripheral circulatory complications	0.503	0.497	0.000
E12.4 With neurological complications	0.503	0.497	0.000
E12.3 With ophthalmic complications	0.503	0.497	0.000
E12.2 With renal complications	0.503	0.497	0.000
E12.1 With ketoacidosis	0.503	0.497	0.000
E12.0 With coma	0.503	0.497	0.000
E67.8 Other specified hyperalimentation	0.499	0.501	0.000
E67.3 Hypervitaminosis D	0.499	0.501	0.000
E67.2 Megavitamin-B6 syndrome	0.499	0.501	0.000
E67.1 Hypercarotenaemia	0.499	0.501	0.000
E67.0 Hypervitaminosis A	0.499	0.501	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.498	0.501	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.479	0.521	0.000
E50 Vitamin A deficiency	0.479	0.521	0.000
E60 Dietary zinc deficiency	0.479	0.521	0.000
E59 Dietary selenium deficiency	0.479	0.521	0.000
E52 Niacin deficiency [pellagra]	0.479	0.521	0.000
E54 Ascorbic acid deficiency	0.477	0.523	0.000
E63 Other nutritional deficiencies	0.469	0.531	0.000
E56 Other vitamin deficiencies	0.468	0.532	0.000
E51 Thiamine deficiency	0.454	0.545	0.000
E61.9 Deficiency of nutrient element, unspecified	0.445	0.555	0.000
E61.8 Deficiency of other specified nutrient elements	0.445	0.555	0.000
E61.7 Deficiency of multiple nutrient elements	0.445	0.555	0.000
E61.6 Vanadium deficiency	0.445	0.555	0.000
E61.5 Molybdenum deficiency	0.445	0.555	0.000
E61.4 Chromium deficiency	0.445	0.555	0.000
E61.3 Manganese deficiency	0.445	0.555	0.000
E61.0 Copper deficiency	0.445	0.555	0.000
E13.8 With unspecified complications	0.436	0.564	0.000
E13.7 With multiple complications	0.436	0.564	0.000
E13.6 With other specified complications	0.436	0.564	0.000
E13.5 With peripheral circulatory complications	0.436	0.564	0.000
E13.4 With neurological complications	0.436	0.564	0.000
E13.2 With renal complications	0.436	0.564	0.000
E13.1 With ketoacidosis	0.436	0.564	0.000
E13.0 With coma	0.436	0.564	0.000
E61.2 Magnesium deficiency	0.433	0.567	0.000
E10.3 With ophthalmic complications	0.424	0.576	0.000
E13.3 With ophthalmic complications	0.416	0.584	0.000
E13.9 Without complications	0.370	0.630	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.368	0.632	0.000
E45 Retarded development following protein-energy malnutrition	0.368	0.632	0.000
E43 Unspecified severe protein-energy malnutrition	0.368	0.632	0.000
E42 Marasmic kwashiorkor	0.368	0.632	0.000
E41 Nutritional marasmus	0.368	0.632	0.000
E40 Kwashiorkor	0.368	0.632	0.000
E15 Nondiabetic hypoglycaemic coma	0.357	0.642	0.000
E55 Vitamin D deficiency	0.351	0.649	0.000
E50.9 Vitamin A deficiency, unspecified	0.344	0.656	0.000
E50.8 Other manifestations of vitamin A deficiency	0.344	0.656	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.344	0.656	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.344	0.656	0.000
E50.5 Vitamin A deficiency with night blindness	0.344	0.656	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.344	0.656	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.344	0.656	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.344	0.656	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.344	0.656	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.344	0.656	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.344	0.656	0.000
E64.8 Sequelae of other nutritional deficiencies	0.344	0.656	0.000
E64.3 Sequelae of rickets	0.344	0.656	0.000
E64.2 Sequelae of vitamin C deficiency	0.344	0.656	0.000
E64.1 Sequelae of vitamin A deficiency	0.344	0.656	0.000
E64.0 Sequelae of protein-energy malnutrition	0.344	0.656	0.000
E63.8 Other specified nutritional deficiencies	0.336	0.664	0.000
E63.1 Imbalance of constituents of food intake	0.336	0.664	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.336	0.664	0.000
E56.9 Vitamin deficiency, unspecified	0.336	0.664	0.000
E56.8 Deficiency of other vitamins	0.336	0.664	0.000
E56.0 Deficiency of vitamin E	0.336	0.664	0.000
E10.1 With ketoacidosis	0.327	0.673	0.000
E51.9 Thiamine deficiency, unspecified	0.326	0.674	0.000
E51.8 Other manifestations of thiamine deficiency	0.326	0.674	0.000
E51.1 Beriberi	0.326	0.674	0.000
E63.9 Nutritional deficiency, unspecified	0.326	0.674	0.000
E56.1 Deficiency of vitamin K	0.324	0.675	0.000
E51.2 Wernicke's encephalopathy	0.301	0.698	0.000
E44.1 Mild protein-energy malnutrition	0.264	0.736	0.000
E44.0 Moderate protein-energy malnutrition	0.264	0.736	0.000
E55.0 Rickets, active	0.251	0.748	0.000
E53 Deficiency of other B group vitamins	0.241	0.758	0.001
E46 Unspecified protein-energy malnutrition	0.210	0.789	0.001
G56.0 Carpal tunnel syndrome	0.190	0.810	0.000
E16 Other disorders of pancreatic internal secretion	0.186	0.814	0.000
E53.1 Pyridoxine deficiency	0.173	0.826	0.001
E53.0 Riboflavin deficiency	0.173	0.826	0.001
I10 Essential (primary) hypertension	0.174	0.826	0.000
E53.9 Vitamin B deficiency, unspecified	0.144	0.856	0.001
E16.9 Disorder of pancreatic internal secretion, unspecified	0.133	0.866	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.133	0.866	0.000
E16.4 Abnormal secretion of gastrin	0.133	0.866	0.000
E16.3 Increased secretion of glucagon	0.133	0.866	0.000
E16.1 Other hypoglycaemia	0.127	0.873	0.000
E55.9 Vitamin D deficiency, unspecified	0.123	0.877	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.116	0.884	0.000
I10-I15 Hypertensive diseases	0.101	0.899	0.000
G56 Mononeuropathies of upper limb	0.098	0.902	0.000
G40-G47 Episodic and paroxysmal disorders	0.092	0.908	0.000
E00-E07 Disorders of thyroid gland	0.091	0.909	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.088	0.912	0.000
G43 Migraine	0.084	0.916	0.000
G47 Sleep disorders	0.083	0.917	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.083	0.917	0.000
I15 Secondary hypertension	0.082	0.918	0.000
G44 Other headache syndromes	0.082	0.918	0.000
J22 Unspecified acute lower respiratory infection	0.081	0.919	0.000
G43.1 Migraine with aura [classical migraine]	0.081	0.919	0.000
G47.3 Sleep apnoea	0.080	0.920	0.000
I12 Hypertensive renal disease	0.079	0.921	0.000
Z86.4 Personal history of psychoactive substance abuse	0.079	0.921	0.000
I84.6 Residual haemorrhoidal skin tags	0.079	0.921	0.000
G56.8 Other mononeuropathies of upper limb	0.076	0.924	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.075	0.925	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.074	0.926	0.000
G44.2 Tension-type headache	0.074	0.926	0.000
I13 Hypertensive heart and renal disease	0.074	0.926	0.000
G41 Status epilepticus	0.073	0.927	0.000
G59.0 Diabetic mononeuropathy	0.073	0.927	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.073	0.927	0.000
G56.3 Lesion of radial nerve	0.072	0.928	0.000
G43.8 Other migraine	0.071	0.929	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.071	0.929	0.000
G56.1 Other lesions of median nerve	0.070	0.930	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.070	0.930	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.070	0.930	0.000
G40 Epilepsy	0.070	0.930	0.000
I12.9 Hypertensive renal disease without renal failure	0.070	0.930	0.000
G45.0 Vertebro-basilar artery syndrome	0.066	0.934	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.065	0.935	0.000
E00 Congenital iodine-deficiency syndrome	0.065	0.935	0.000
Chapter VI Diseases of the nervous system	0.065	0.935	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.065	0.935	0.000
I15.1 Hypertension secondary to other renal disorders	0.065	0.935	0.000
I15.8 Other secondary hypertension	0.065	0.935	0.000
G45.3 Amaurosis fugax	0.065	0.935	0.000
G56.4 Causalgia	0.065	0.935	0.000
E07 Other disorders of thyroid	0.065	0.935	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.063	0.937	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.063	0.937	0.000
G44.0 Cluster headache syndrome	0.063	0.937	0.000
G40.9 Epilepsy, unspecified	0.063	0.937	0.000
I15.0 Renovascular hypertension	0.063	0.937	0.000
G43.0 Migraine without aura [common migraine]	0.062	0.938	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.061	0.939	0.000
G43.3 Complicated migraine	0.061	0.939	0.000
G47.2 Disorders of the sleep-wake schedule	0.060	0.940	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.060	0.940	0.000
G46.4 Cerebellar stroke syndrome	0.060	0.940	0.000
G44.1 Vascular headache, not elsewhere classified	0.059	0.941	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.058	0.942	0.000
G44.3 Chronic posttraumatic headache	0.058	0.942	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.058	0.942	0.000
I11 Hypertensive heart disease	0.057	0.942	0.000
G47.4 Narcolepsy and cataplexy	0.058	0.942	0.000
G41.9 Status epilepticus, unspecified	0.057	0.943	0.000
G45.4 Transient global amnesia	0.057	0.943	0.000
G43.2 Status migrainosus	0.057	0.943	0.000
I15.9 Seconday hypertension, unspecified	0.057	0.943	0.000
G46.3 Brain stem stroke syndrome	0.056	0.943	0.000
G46.7 Other lacunar syndromes	0.056	0.944	0.000
G70-G73 Diseases of myoneural junction and muscle	0.056	0.944	0.000
I15.2 Hypertension secondary to endocrine disorders	0.055	0.944	0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.054	0.946	0.000
G46.6 Pure sensory lacunar syndrome	0.054	0.946	0.000
G46.5 Pure motor lacunar syndrome	0.054	0.946	0.000
G46.1 Anterior cerebral artery syndrome	0.054	0.946	0.000
G46.0 Middle cerebral artery syndrome	0.054	0.946	0.000
G46.2 Posterior cerebral artery syndrome	0.054	0.946	0.000
G41.0 Grand mal status epilepticus	0.054	0.946	0.000
G41.8 Other status epilepticus	0.054	0.946	0.000
G40.8 Other epilepsy	0.054	0.946	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.053	0.947	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.053	0.947	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.053	0.947	0.000
G41.1 Petit mal status epilepticus	0.052	0.947	0.000
E07.9 Disorder of thyroid, unspecified	0.052	0.948	0.000
G41.2 Complex partial status epilepticus	0.052	0.948	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.052	0.948	0.000
G47.8 Other sleep disorders	0.052	0.948	0.000
G59.8 Other mononeuropathies in diseases classified elsewhere	0.051	0.949	0.000
G40.5 Special epileptic syndromes	0.050	0.950	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.049	0.950	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.049	0.951	0.000
G52 Disorders of other cranial nerves	0.049	0.951	0.000
G54 Nerve root and plexus disorders	0.049	0.951	0.000
G47.9 Sleep disorder, unspecified	0.048	0.952	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.047	0.953	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.047	0.953	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.047	0.953	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.047	0.953	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.047	0.953	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.047	0.953	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.047	0.953	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.047	0.953	0.000
E07.1 Dyshormogenetic goitre	0.046	0.953	0.000
E07.0 Hypersecretion of calcitonin	0.046	0.953	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.046	0.954	0.000
G72 Other myopathies	0.045	0.954	0.000
J20-J22 Other acute lower respiratory infections	0.045	0.955	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.044	0.955	0.000
I12.0 Hypertensive renal disease with renal failure	0.044	0.956	0.000
G44.8 Other specified headache syndromes	0.044	0.956	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.043	0.957	0.000
G71 Primary disorders of muscles	0.043	0.957	0.000
G70 Myasthenia gravis and other myoneural disorders	0.043	0.957	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.042	0.958	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.042	0.958	0.000
G51 Facial nerve disorders	0.041	0.959	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.040	0.959	0.000
G30-G32 Other degenerative diseases of the nervous system	0.040	0.960	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.040	0.960	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.040	0.960	0.000
E70-E90 Metabolic disorders	0.040	0.960	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.039	0.961	0.000
G54.1 Lumbosacral plexus disorders	0.039	0.961	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.038	0.962	0.000
G52.3 Disorders of hypoglossal nerve	0.037	0.963	0.000
G54.2 Cervical root disorders, not elsewhere classified	0.037	0.963	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.037	0.963	0.000
E07.8 Other specified disorders of thyroid	0.037	0.963	0.000
G52.9 Cranial nerve disorder, unspecified	0.037	0.963	0.000
G71.0 Muscular dystrophy	0.037	0.963	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.037	0.963	0.000
G63.2 Diabetic polyneuropathy	0.036	0.964	0.000
G54.8 Other nerve root and plexus disorders	0.036	0.964	0.000
G52.2 Disorders of vagus nerve	0.036	0.964	0.000
G52.0 Disorders of olfactory nerve	0.035	0.964	0.000
G54.7 Phantom limb syndrome without pain	0.035	0.965	0.000
G54.3 Thoracic root disorders, not elsewhere classified	0.035	0.965	0.000
I85 Oesophageal varices	0.035	0.965	0.000
E16.2 Hypoglycaemia, unspecified	0.035	0.965	0.000
I85.9 Oesophageal varices without bleeding	0.035	0.965	0.000
E06 Thyroiditis	0.035	0.965	0.000
G62 Other polyneuropathies	0.035	0.965	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.035	0.965	0.000
G54.5 Neuralgic amyotrophy	0.035	0.965	0.000
E85 Amyloidosis	0.035	0.965	0.000
G20-G26 Extrapyramidal and movement disorders	0.035	0.965	0.000
G72.9 Myopathy, unspecified	0.034	0.966	0.000
G52.7 Disorders of multiple cranial nerves	0.034	0.966	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.032	0.966	0.002
G52.1 Disorders of glossopharyngeal nerve	0.034	0.966	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.034	0.966	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.034	0.966	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.034	0.966	0.000
I80 Phlebitis and thrombophlebitis	0.034	0.966	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.034	0.966	0.000
G72.8 Other specified myopathies	0.034	0.966	0.000
I84 Haemorrhoids	0.034	0.966	0.000
G70.0 Myasthenia gravis	0.033	0.967	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.033	0.967	0.000
G10 Huntington's disease	0.033	0.967	0.000
G11 Hereditary ataxia	0.033	0.967	0.000
I82 Other venous embolism and thrombosis	0.033	0.967	0.000
G70.9 Myoneural disorder, unspecified	0.033	0.967	0.000
G73.0 Myasthenic syndromes in endocrine diseases	0.033	0.967	0.000
I89.0 Lymphoedema, not elsewhere classified	0.033	0.967	0.000
I84.4 External haemorrhoids with other complications	0.033	0.967	0.000
G51.3 Clonic hemifacial spasm	0.033	0.967	0.000
G72.3 Periodic paralysis	0.033	0.967	0.000
G72.2 Myopathy due to other toxic agents	0.033	0.967	0.000
G54.4 Lumbosacral root disorders, not elsewhere classified	0.033	0.967	0.000
G58 Other mononeuropathies	0.032	0.967	0.000
E84 Cystic fibrosis	0.032	0.968	0.000
G72.0 Drug-induced myopathy	0.032	0.968	0.000
E03 Other hypothyroidism	0.032	0.968	0.000
G72.1 Alcoholic myopathy	0.032	0.968	0.000
G52.8 Disorders of other specified cranial nerves	0.032	0.968	0.000
G51.9 Disorder of facial nerve, unspecified	0.032	0.968	0.000
G03 Meningitis due to other and unspecified causes	0.032	0.968	0.000
G54.6 Phantom limb syndrome with pain	0.032	0.968	0.000
Chapter IX Diseases of the circulatory system	0.031	0.969	0.000
G64 Other disorders of peripheral nervous system	0.031	0.969	0.000
J21 Acute bronchiolitis	0.031	0.969	0.000
G53.8 Other cranial nerve disorders in other diseases classified elsewhere	0.031	0.969	0.000
G53.3 Multiple cranial nerve palsies in neoplastic disease	0.031	0.969	0.000
G53.2 Multiple cranial nerve palsies in sarcoidosis	0.031	0.969	0.000
G53.1 Multiple cranial nerve palsies in infectious and parasitic diseases classified elsewhere	0.031	0.969	0.000
G60 Hereditary and idiopathic neuropathy	0.031	0.969	0.000
G71.9 Primary disorder of muscle, unspecified	0.031	0.969	0.000
G71.8 Other primary disorders of muscles	0.031	0.969	0.000
G71.2 Congenital myopathies	0.031	0.969	0.000
G70.2 Congenital and developmental myasthenia	0.031	0.969	0.000
G70.1 Toxic myoneural disorders	0.031	0.969	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.031	0.969	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.031	0.969	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.030	0.970	0.000
G73.6 Myopathy in metabolic diseases	0.030	0.970	0.000
G73.5 Myopathy in endocrine diseases	0.030	0.970	0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.030	0.970	0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.030	0.970	0.000
G73.2 Other myasthenic syndromes in neoplastic disease	0.030	0.970	0.000
G73.1 Eaton-Lambert syndrome	0.030	0.970	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.030	0.970	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.030	0.970	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.030	0.970	0.000
J20 Acute bronchitis	0.030	0.970	0.000
G62.9 Polyneuropathy, unspecified	0.030	0.970	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.030	0.970	0.000
E79 Disorders of purine and pyrimidine metabolism	0.030	0.970	0.000
I82.8 Embolism and thrombosis of other specified veins	0.030	0.970	0.000
G51.4 Facial myokymia	0.029	0.971	0.000
G51.2 Melkersson's syndrome	0.029	0.971	0.000
G51.1 Geniculate ganglionitis	0.029	0.971	0.000
E73 Lactose intolerance	0.029	0.971	0.000
E70 Disorders of aromatic amino-acid metabolism	0.029	0.971	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.029	0.971	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.029	0.971	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.029	0.971	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.029	0.971	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.029	0.971	0.000
G63.1 Polyneuropathy in neoplastic disease	0.029	0.971	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.029	0.971	0.000
G12 Spinal muscular atrophy and related syndromes	0.029	0.971	0.000
G73.7 Myopathy other diseases classified elsewhere	0.029	0.971	0.000
E53.8 Deficiency of other specified B group vitamins	0.028	0.971	0.001
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.029	0.971	0.000
E76 Disorders of glycosaminoglycan metabolism	0.029	0.971	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.029	0.971	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.029	0.971	0.000
E77 Disorders of glycoprotein metabolism	0.029	0.971	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.029	0.971	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.029	0.971	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.029	0.971	0.000
G71.1 Myotonic disorders	0.029	0.971	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.029	0.971	0.000
G70.8 Other specified myoneural disorders	0.029	0.971	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.029	0.971	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.029	0.971	0.000
Q60-Q64 Congenital malformations of the urinary system	0.028	0.972	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.028	0.972	0.000
G14 Postpolio syndrome	0.028	0.972	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.028	0.972	0.000
G23 Other degenerative diseases of basal ganglia	0.028	0.972	0.000
G24 Dystonia	0.028	0.972	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.028	0.972	0.000
E85.4 Organ-limited amyloidosis	0.028	0.972	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.027	0.972	0.000
E85.3 Secondary systemic amyloidosis	0.027	0.973	0.000
Q23 Congenital malformations of aortic and mitral valves	0.027	0.973	0.000
# Top node	0.027	0.973	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.027	0.973	0.000
G11.4 Hereditary spastic paraplegia	0.027	0.973	0.000
Q61 Cystic kidney disease	0.027	0.973	0.000
G50 Disorders of trigeminal nerve	0.026	0.973	0.001
G62.1 Alcoholic polyneuropathy	0.027	0.973	0.000
E85.9 Amyloidosis, unspecified	0.027	0.973	0.000
G37 Other demyelinating diseases of central nervous system	0.026	0.973	0.001
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.027	0.973	0.000
I82.0 Budd-Chiari syndrome	0.026	0.973	0.000
E72 Other disorders of amino-acid metabolism	0.026	0.973	0.000
E74 Other disorders of carbohydrate metabolism	0.026	0.973	0.000
E85.8 Other amyloidosis	0.026	0.974	0.000
I89.1 Lymphangitis	0.026	0.974	0.000
E05.8 Other thyrotoxicosis	0.026	0.974	0.000
G30 Alzheimer's disease	0.026	0.974	0.000
I81 Portal vein thrombosis	0.026	0.974	0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.026	0.974	0.000
I82.3 Embolism and thrombosis of renal vein	0.026	0.974	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.026	0.974	0.000
Q23.1 Congenital insufficiency of aortic valve	0.026	0.974	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.025	0.974	0.000
G54.0 Brachial plexus disorders	0.025	0.974	0.000
I84.0 Internal thrombosed haemorrhoids	0.025	0.974	0.000
E84.9 Cystic fibrosis, unspecified	0.025	0.975	0.000
Q61.2 Polycystic kidney, adult type	0.025	0.975	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.025	0.975	0.000
E06.4 Drug-induced thyroiditis	0.025	0.975	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.025	0.975	0.000
E06.0 Acute thyroiditis	0.025	0.975	0.000
G62.2 Polyneuropathy due to other toxic agents	0.025	0.975	0.000
J00-J06 Acute upper respiratory infections	0.025	0.975	0.000
G51.8 Other disorders of facial nerve	0.025	0.975	0.000
I85.0 Oesophageal varices with bleeding	0.025	0.975	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.025	0.975	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.025	0.975	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.025	0.975	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.025	0.975	0.000
Q61.3 Polycystic kidney, unspecified	0.025	0.975	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.025	0.975	0.000
G22 Parkinsonism in diseases classified elsewhere	0.025	0.975	0.000
Q24 Other congenital malformations of heart	0.025	0.975	0.000
J06.9 Acute upper respiratory infection, unspecified	0.025	0.975	0.000
J00 Acute nasopharyngitis [common cold]	0.025	0.975	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.025	0.975	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.024	0.975	0.000
G03.9 Meningitis, unspecified	0.025	0.975	0.000
G58.7 Mononeuritis multiplex	0.025	0.975	0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.025	0.975	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.025	0.975	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.025	0.975	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.025	0.975	0.000
G11.1 Early-onset cerebellar ataxia	0.024	0.975	0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.024	0.975	0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.024	0.975	0.000
G36 Other acute disseminated demyelination	0.023	0.975	0.002
G60.0 Hereditary motor and sensory neuropathy	0.024	0.975	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.024	0.975	0.000
G62.0 Drug-induced polyneuropathy	0.024	0.976	0.000
Chapter X Diseases of the respiratory system	0.024	0.976	0.000
I88 Nonspecific lymphadenitis	0.024	0.976	0.000
E20-E35 Disorders of other endocrine glands	0.021	0.976	0.004
G24.5 Blepharospasm	0.024	0.976	0.000
E88 Other metabolic disorders	0.024	0.976	0.000
E05.5 Thyroid crisis or storm	0.024	0.976	0.000
E05.4 Thyrotoxicosis factitia	0.024	0.976	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.024	0.976	0.000
G11.8 Other hereditary ataxias	0.024	0.976	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.024	0.976	0.000
G11.2 Late-onset cerebellar ataxia	0.024	0.976	0.000
G11.0 Congenital nonprogressive ataxia	0.024	0.976	0.000
G53.0 Postzoster neuralgia	0.024	0.976	0.000
E06.5 Other chronic thyroiditis	0.024	0.976	0.000
I82.1 Thrombophlebitis migrans	0.024	0.976	0.000
E78.8 Other disorders of lipoprotein metabolism	0.024	0.976	0.000
G58.0 Intercostal neuropathy	0.024	0.976	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.024	0.976	0.000
G00 Bacterial meningitis, not elsewhere classified	0.023	0.976	0.000
O48 Prolonged pregnancy	0.000	0.976	0.024
E84.8 Cystic fibrosis with other manifestations	0.023	0.976	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.023	0.976	0.000
G31.0 Circumscribed brain atrophy	0.023	0.976	0.000
E03.5 Myxoedema coma	0.023	0.977	0.000
E03.4 Atrophy of thyroid (acquired)	0.023	0.977	0.000
E03.3 Postinfectious hypothyroidism	0.023	0.977	0.000
E06.1 Subacute thyroiditis	0.023	0.977	0.000
Q50-Q56 Congenital malformations of genital organs	0.023	0.977	0.000
G03.8 Meningitis due to other specified causes	0.023	0.977	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.023	0.977	0.000
G03.1 Chronic meningitis	0.023	0.977	0.000
G03.0 Nonpyogenic meningitis	0.023	0.977	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.023	0.977	0.000
Q00-Q07 Congenital malformations of the nervous system	0.023	0.977	0.000
Q21 Congenital malformations of cardiac septa	0.023	0.977	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.022	0.977	0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.023	0.977	0.000
G21 Secondary Parkinsonism	0.023	0.977	0.000
Q35-Q37 Cleft lip and cleft palate	0.023	0.977	0.000
J21.8 Acute bronchiolitis due to other specified organisms	0.023	0.977	0.000
J21.1 Acute bronchiolitis due to human metapneumovirus	0.023	0.977	0.000
J21.0 Acute bronchiolitis due to respiratory syncytial virus	0.023	0.977	0.000
G60.3 Idiopathic progressive neuropathy	0.022	0.977	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.022	0.977	0.000
G60.1 Refsum's disease	0.022	0.977	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.022	0.977	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations