TreeWAS – Variant ID: rs291671

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
C44.6 Skin of upper limb, including shoulder	1.000	0.000
C44.5 Skin of trunk	1.000	0.000
C44.3 Skin of other and unspecified parts of face	1.000	0.000
C44 Other malignant neoplasms of skin	1.000	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	1.000	0.000
N40 Hyperplasia of prostate	1.000	0.000
Chapter II Neoplasms	1.000	0.000
C44.4 Skin of scalp and neck	1.000	0.000
C43 Malignant melanoma of skin	1.000	0.000
L57.0 Actinic keratosis	0.999	0.001
N40-N51 Diseases of male genital organs	0.998	0.002
N41 Inflammatory diseases of prostate	0.998	0.002
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.997	0.003
N41.1 Chronic prostatitis	0.996	0.004
L57 Skin changes due to chronic exposure to nonionising radiation	0.996	0.004
C50-C50 Malignant neoplasm of breast	0.993	0.007
C43.5 Malignant melanoma of trunk	0.993	0.007
C44.1 Skin of eyelid, including canthus	0.993	0.007
C50 Malignant neoplasm of breast	0.989	0.011
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.986	0.014
C44.7 Skin of lower limb, including hip	0.983	0.017
C64-C68 Malignant neoplasms of urinary tract	0.979	0.021
C43.6 Malignant melanoma of upper limb, including shoulder	0.978	0.022
D37-D48 Neoplasms of uncertain or unknown behaviour	0.975	0.025
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.974	0.026
M20-M25 Other joint disorders	0.972	0.028
N41.0 Acute prostatitis	0.967	0.033
M80-M85 Disorders of bone density and structure	0.966	0.034
Chapter XII Diseases of the skin and subcutaneous tissue	0.966	0.034
D46 Myelodysplastic syndromes	0.964	0.036
M23 Internal derangement of knee	0.963	0.037
D00-D09 In situ neoplasms	0.959	0.041
C44.2 Skin of ear and external auricular canal	0.958	0.042
C44.0 Skin of lip	0.957	0.043
C50.3 Lower-inner quadrant of breast	0.956	0.044
L80-L99 Other disorders of the skin and subcutaneous tissue	0.951	0.049
C67 Malignant neoplasm of bladder	0.949	0.051
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.949	0.051
D46.9 Myelodysplastic syndrome, unspecified	0.947	0.053
M23.2 Derangement of meniscus due to old tear or injury	0.946	0.054
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.939	0.061
L85 Other epidermal thickening	0.937	0.063
D04 Carcinoma in situ of skin	0.937	0.063
C44.9 Malignant neoplasm of skin, unspecified	0.936	0.064
# Top node	0.934	0.066
M65-M68 Disorders of synovium and tendon	0.925	0.075
M40-M43 Deforming dorsopathies	0.919	0.081
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.917	0.083
M84 Disorders of continuity of bone	0.917	0.083
M23.8 Other internal derangements of knee	0.912	0.088
M80 Osteoporosis with pathological fracture	0.904	0.096
M24 Other specific joint derangements	0.899	0.101
C50.9 Breast, unspecified	0.895	0.105
C71 Malignant neoplasm of brain	0.895	0.105
L85.9 Epidermal thickening, unspecified	0.890	0.110
M67 Other disorders of synovium and tendon	0.889	0.111
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.886	0.114
L56 Other acute skin changes due to ultraviolet radiation	0.885	0.115
M84.1 Nonunion of fracture [pseudarthrosis]	0.885	0.115
Chapter XIV Diseases of the genitourinary system	0.885	0.115
L85.8 Other specified epidermal thickening	0.875	0.125
C67.8 Overlapping lesion of bladder	0.869	0.131
M85 Other disorders of bone density and structure	0.865	0.135
L83 Acanthosis nigricans	0.854	0.146
C50.4 Upper-outer quadrant of breast	0.854	0.146
C67.2 Lateral wall of bladder	0.854	0.146
M41 Scoliosis	0.853	0.147
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.850	0.150
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.848	0.152
C66 Malignant neoplasm of ureter	0.842	0.158
D47.1 Chronic myeloproliferative disease	0.838	0.162
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.838	0.162
C50.0 Nipple and areola	0.834	0.166
M86-M90 Other osteopathies	0.834	0.166
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.833	0.167
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.830	0.170
C50.8 Overlapping lesion of breast	0.829	0.171
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.824	0.176
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.824	0.176
C65 Malignant neoplasm of renal pelvis	0.820	0.180
L89 Decubitus ulcer	0.817	0.183
M67.8 Other specified disorders of synovium and tendon	0.816	0.184
C67.6 Ureteric orifice	0.815	0.185
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.812	0.188
M85.8 Other specified disorders of bone density and structure	0.811	0.189
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.809	0.191
D04.6 Skin of upper limb, including shoulder	0.809	0.191
M32 Systemic lupus erythematosus	0.808	0.192
M41.9 Scoliosis, unspecified	0.806	0.194
C43.3 Malignant melanoma of other and unspecified parts of face	0.800	0.200
C43.2 Malignant melanoma of ear and external auricular canal	0.800	0.200
M66 Spontaneous rupture of synovium and tendon	0.800	0.200
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.799	0.201
C43.7 Malignant melanoma of lower limb, including hip	0.798	0.202
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.797	0.203
D07 Carcinoma in situ of other and unspecified genital organs	0.797	0.203
C43.4 Malignant melanoma of scalp and neck	0.795	0.205
L81 Other disorders of pigmentation	0.794	0.206
C71.9 Brain, unspecified	0.794	0.206
C50.1 Central portion of breast	0.793	0.206
C43.1 Malignant melanoma of eyelid, including canthus	0.793	0.207
C71.0 Cerebrum, except lobes and ventricles	0.791	0.209
D04.2 Skin of ear and external auricular canal	0.791	0.209
D04.3 Skin of other and unspecified parts of face	0.791	0.209
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.789	0.211
M80.9 Unspecified osteoporosis with pathological fracture	0.789	0.211
M30 Polyarteritis nodosa and related conditions	0.785	0.215
L50-L54 Urticaria and erythema	0.784	0.216
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.783	0.217
D04.5 Skin of trunk	0.782	0.218
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.781	0.219
D46.4 Refractory anaemia, unspecified	0.778	0.222
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.777	0.223
C50.6 Axillary tail of breast	0.775	0.225
M40 Kyphosis and lordosis	0.775	0.225
N44 Torsion of testis	0.774	0.226
D47.3 Essential (haemorrhagic) thrombocythaemia	0.774	0.226
L89.0 Stage I decubitus ulcer and pressure area	0.772	0.228
M60-M63 Disorders of muscles	0.771	0.229
M34 Systemic sclerosis	0.771	0.229
M24.2 Disorder of ligament	0.771	0.229
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.769	0.231
M35 Other systemic involvement of connective tissue	0.767	0.233
C40-C41 Malignant neoplasms of bone and articular cartilage	0.765	0.235
C69 Malignant neoplasm of eye and adnexa	0.764	0.236
D03 Melanoma in situ	0.762	0.238
N48 Other disorders of penis	0.760	0.240
M23.80 Other internal derangements of knee (Multiple sites)	0.759	0.241
D47.4 Osteomyelofibrosis	0.755	0.245
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.755	0.245
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.755	0.245
M67.1 Other contracture of tendon (sheath)	0.754	0.246
L90 Atrophic disorders of skin	0.754	0.246
L94 Other localised connective tissue disorders	0.754	0.246
D46.2 Refractory anaemia with excess of blasts	0.753	0.247
M80.5 Idiopathic osteoporosis with pathological fracture	0.750	0.250
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.746	0.254
L57.4 Cutis laxa senilis	0.744	0.256
C71.3 Parietal lobe	0.742	0.258
N46 Male infertility	0.737	0.263
C67.5 Bladder neck	0.737	0.263
M23.9 Internal derangement of knee, unspecified	0.737	0.263
D46.7 Other myelodysplastic syndromes	0.736	0.264
C43.9 Malignant melanoma of skin, unspecified	0.736	0.264
Q50-Q56 Congenital malformations of genital organs	0.735	0.265
D07.5 Prostate	0.735	0.265
D41.4 Bladder	0.733	0.267
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.724	0.276
M25 Other joint disorders, not elsewhere classified	0.719	0.281
D04.7 Skin of lower limb, including hip	0.717	0.283
C44.8 Overlapping lesion of skin	0.717	0.283
C43.8 Overlapping malignant melanoma of skin	0.717	0.283
C43.0 Malignant melanoma of lip	0.717	0.283
M35.3 Polymyalgia rheumatica	0.716	0.284
N51 Disorders of male genital organs in diseases classified elsewhere	0.716	0.284
N41.8 Other inflammatory diseases of prostate	0.715	0.284
N41.3 Prostatocystitis	0.715	0.284
N41.2 Abscess of prostate	0.715	0.284
L97 Ulcer of lower limb, not elsewhere classified	0.715	0.285
M24.4 Recurrent dislocation and subluxation of joint	0.715	0.285
M80.0 Postmenopausal osteoporosis with pathological fracture	0.714	0.286
L57.5 Actinic granuloma	0.714	0.286
L57.3 Poikiloderma of Civatte	0.714	0.286
L57.2 Cutis rhomboidalis nuchae	0.714	0.286
L57.1 Actinic reticuloid	0.714	0.286
D04.4 Skin of scalp and neck	0.712	0.288
Q66 Congenital deformities of feet	0.709	0.291
L00-L08 Infections of the skin and subcutaneous tissue	0.709	0.291
C73 Malignant neoplasm of thyroid gland	0.708	0.292
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.707	0.293
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.707	0.293
L58 Radiodermatitis	0.707	0.293
L55 Sunburn	0.707	0.293
M67.0 Short Achilles tendon (acquired)	0.707	0.293
C67.3 Anterior wall of bladder	0.705	0.295
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.703	0.296
C68 Malignant neoplasm of other and unspecified urinary organs	0.702	0.298
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.702	0.298
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.701	0.299
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.699	0.301
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.699	0.301
Q80-Q89 Other congenital malformations	0.698	0.302
M23.0 Cystic meniscus	0.697	0.303
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.697	0.303
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.696	0.303
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.696	0.303
M24.5 Contracture of joint	0.695	0.305
L81.8 Other specified disorders of pigmentation	0.695	0.305
M24.6 Ankylosis of joint	0.694	0.306
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.693	0.307
C67.4 Posterior wall of bladder	0.693	0.307
M83 Adult osteomalacia	0.693	0.307
L50 Urticaria	0.692	0.308
C04 Malignant neoplasm of floor of mouth	0.692	0.308
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.691	0.309
D46.5 Refractory anaemia with multi-lineage dysplasia	0.691	0.309
D46.3 Refractory anaemia with excess of blasts with transformation	0.691	0.309
D46.1 Refractory anaemia with sideroblasts	0.691	0.309
D46.0 Refractory anaemia without sideroblasts, so stated	0.691	0.309
M00-M03 Infectious arthropathies	0.690	0.310
M32.1 Systemic lupus erythematosus with organ or system involvement	0.690	0.310
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.689	0.311
Chapter XX External causes of morbidity and mortality	0.688	0.312
D01 Carcinoma in situ of other and unspecified digestive organs	0.687	0.313
L10-L14 Bullous disorders	0.686	0.314
M87 Osteonecrosis	0.683	0.317
D43.2 Brain, unspecified	0.682	0.318
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.682	0.318
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.682	0.318
L87 Transepidermal elimination disorders	0.682	0.318
L88 Pyoderma gangrenosum	0.682	0.318
L86 Keratoderma in diseases classified elsewhere	0.682	0.318
M84.4 Pathological fracture, not elsewhere classified	0.681	0.319
C67.7 Urachus	0.680	0.320
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.680	0.320
C70 Malignant neoplasm of meninges	0.680	0.320
M24.26 Disorder of ligament (Lower leg)	0.680	0.320
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.679	0.321
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.678	0.322
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.678	0.322
L80 Vitiligo	0.678	0.322
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.676	0.324
L85.3 Xerosis cutis	0.672	0.328
L85.2 Keratosis punctata (palmaris et plantaris)	0.672	0.328
L85.0 Acquired ichthyosis	0.672	0.328
D04.9 Skin, unspecified	0.671	0.328
D04.8 Skin of other sites	0.671	0.328
D04.1 Skin of eyelid, including canthus	0.671	0.328
D04.0 Skin of lip	0.671	0.328
M40.2 Other and unspecified kyphosis	0.671	0.328
M90 Osteopathies in diseases classified elsewhere	0.671	0.329
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.670	0.330
Chapter XVI Certain conditions originating in the perinatal period	0.670	0.330
C11 Malignant neoplasm of nasopharynx	0.670	0.330
M23.1 Discoid meniscus (congenital)	0.669	0.331
M23.4 Loose body in knee	0.669	0.331
C67.0 Trigone of bladder	0.668	0.332
L08 Other local infections of skin and subcutaneous tissue	0.667	0.333
L93 Lupus erythematosus	0.667	0.333
M31 Other necrotising vasculopathies	0.665	0.335
L90.5 Scar conditions and fibrosis of skin	0.664	0.336
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.663	0.336
M67.2 Synovial hypertrophy, not elsewhere classified	0.663	0.337
C80 Malignant neoplasm without specification of site	0.663	0.337
M21 Other acquired deformities of limbs	0.663	0.337
M25.3 Other instability of joint	0.662	0.338
M24.8 Other specific joint derangements, not elsewhere classified	0.661	0.338
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.661	0.339
M23.5 Chronic instability of knee	0.659	0.341
M42 Spinal osteochondrosis	0.659	0.341
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.658	0.342
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.658	0.342
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.658	0.342
M84.9 Disorder of continuity of bone, unspecified	0.657	0.342
M84.8 Other disorders of continuity of bone	0.657	0.342
M84.3 Stress fracture, not elsewhere classified	0.657	0.342
M84.2 Delayed union of fracture	0.657	0.342
C71.4 Occipital lobe	0.657	0.343
M91-M94 Chondropathies	0.657	0.343
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.657	0.343
W20-W49 Exposure to inanimate mechanical forces	0.656	0.344
M33 Dermatopolymyositis	0.656	0.344
N48.8 Other specified disorders of penis	0.656	0.344
M82 Osteoporosis in diseases classified elsewhere	0.655	0.345
M23.87 Other internal derangements of knee (Capsular ligament)	0.654	0.346
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.654	0.346
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.654	0.346
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.654	0.346
M24.1 Other articular cartilage disorders	0.654	0.346
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.653	0.346
N49.2 Inflammatory disorders of scrotum	0.653	0.347
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.652	0.348
D43.4 Spinal cord	0.651	0.349
D09 Carcinoma in situ of other and unspecified sites	0.651	0.349
C80.9 Malignant neoplasm, unspecified	0.650	0.350
M81 Osteoporosis without pathological fracture	0.649	0.350
C13 Malignant neoplasm of hypopharynx	0.648	0.352
M80.8 Other osteoporosis with pathological fracture	0.648	0.352
M80.4 Drug-induced osteoporosis with pathological fracture	0.648	0.352
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.648	0.352
M80.2 Osteoporosis of disuse with pathological fracture	0.648	0.352
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.645	0.355
N48.0 Leukoplakia of penis	0.645	0.355
M24.9 Joint derangement, unspecified	0.645	0.355
M24.7 Protrusio acetabuli	0.645	0.355
C71.2 Temporal lobe	0.645	0.355
Q66.8 Other congenital deformities of feet	0.644	0.356
M66.4 Spontaneous rupture of other tendons	0.644	0.356
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.643	0.357
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.643	0.357
C71.7 Brain stem	0.642	0.358
C71.6 Cerebellum	0.642	0.358
C71.5 Cerebral ventricle	0.642	0.358
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.640	0.360
M43 Other deforming dorsopathies	0.640	0.360
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.640	0.360
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.638	0.362
C01 Malignant neoplasm of base of tongue	0.638	0.362
M67.9 Disorder of synovium and tendon, unspecified	0.638	0.362
M67.3 Transient synovitis	0.638	0.362
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.636	0.364
L91 Hypertrophic disorders of skin	0.635	0.365
L81.2 Freckles	0.635	0.365
L56.4 Polymorphous light eruption	0.635	0.365
L56.3 Solar urticaria	0.635	0.365
L56.2 Photocontact dermatitis [berloque dermatitis]	0.635	0.365
L56.1 Drug photoallergic response	0.635	0.365
L56.0 Drug phototoxic response	0.635	0.365
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.634	0.365
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.634	0.365
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.634	0.365
M67.4 Ganglion	0.634	0.366
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.632	0.368
C10 Malignant neoplasm of oropharynx	0.632	0.368
D03.4 Melanoma in situ of scalp and neck	0.631	0.369
M66.3 Spontaneous rupture of flexor tendons	0.631	0.369
M24.21 Disorder of ligament (Shoulder region)	0.629	0.370
M41.99 Scoliosis, unspecified (Site unspecified)	0.629	0.371
C09 Malignant neoplasm of tonsil	0.628	0.372
D02 Carcinoma in situ of middle ear and respiratory system	0.627	0.373
M86 Osteomyelitis	0.626	0.374
M34.8 Other forms of systemic sclerosis	0.625	0.374
L95 Vasculitis limited to skin, not elsewhere classified	0.625	0.375
M85.6 Other cyst of bone	0.624	0.376
Q54 Hypospadias	0.623	0.377
M89 Other disorders of bone	0.622	0.378
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.620	0.380
M85.9 Disorder of bone density and structure, unspecified	0.620	0.380
M85.5 Aneurysmal bone cyst	0.620	0.380
M85.4 Solitary bone cyst	0.620	0.380
M85.3 Osteitis condensans	0.620	0.380
M85.2 Hyperostosis of skull	0.620	0.380
M85.1 Skeletal fluorosis	0.620	0.380
M66.0 Rupture of popliteal cyst	0.616	0.384
D07.4 Penis	0.613	0.387
M25.7 Osteophyte	0.612	0.388
M41.8 Other forms of scoliosis	0.611	0.388
M41.5 Other secondary scoliosis	0.611	0.388
M41.4 Neuromuscular scoliosis	0.611	0.388
M41.3 Thoracogenic scoliosis	0.611	0.388
M41.2 Other idiopathic scoliosis	0.611	0.388
M41.1 Juvenile idiopathic scoliosis	0.611	0.388
M41.0 Infantile idiopathic scoliosis	0.611	0.388
Q67.5 Congenital deformity of spine	0.610	0.390
Q35-Q37 Cleft lip and cleft palate	0.609	0.391
Q30-Q34 Congenital malformations of the respiratory system	0.609	0.391
M22 Disorders of patella	0.609	0.391
M41.94 Scoliosis, unspecified (Thoracic region)	0.608	0.392
N00-N08 Glomerular diseases	0.608	0.392
C08 Malignant neoplasm of other and unspecified major salivary glands	0.608	0.392
C06 Malignant neoplasm of other and unspecified parts of mouth	0.608	0.392
C05 Malignant neoplasm of palate	0.608	0.392
C03 Malignant neoplasm of gum	0.608	0.392
C00 Malignant neoplasm of lip	0.608	0.392
N45 Orchitis and epididymitis	0.606	0.394
V20-V29 Motorcycle rider injured in transport accident	0.606	0.394
M41.96 Scoliosis, unspecified (Lumbar region)	0.606	0.394
M62 Other disorders of muscle	0.603	0.397
C69.9 Eye, unspecified	0.603	0.397
M84.0 Malunion of fracture	0.602	0.398
C67.1 Dome of bladder	0.599	0.401
N60-N64 Disorders of breast	0.599	0.401
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.598	0.402
M24.51 Contracture of joint (Shoulder region)	0.598	0.402
D41.9 Urinary organ, unspecified	0.597	0.402
D41.7 Other urinary organs	0.597	0.402
D41.3 Urethra	0.597	0.402
D41.2 Ureter	0.597	0.402
D41.1 Renal pelvis	0.597	0.402
X58-X59 Accidental exposure to other and unspecified factors	0.597	0.402
Q82 Other congenital malformations of skin	0.596	0.404
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.596	0.404
D41.0 Kidney	0.596	0.404
C75 Malignant neoplasm of other endocrine glands and related structures	0.595	0.405
C74 Malignant neoplasm of adrenal gland	0.595	0.405
C12 Malignant neoplasm of pyriform sinus	0.595	0.405
L94.2 Calcinosis cutis	0.593	0.406
N63 Unspecified lump in breast	0.593	0.407
N48.3 Priapism	0.593	0.407
L92 Granulomatous disorders of skin and subcutaneous tissue	0.593	0.407
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.592	0.407
D03.2 Melanoma in situ of ear and external auricular canal	0.592	0.408
N48.9 Disorder of penis, unspecified	0.592	0.408
C07 Malignant neoplasm of parotid gland	0.589	0.411
L81.9 Disorder of pigmentation, unspecified	0.588	0.412
L50.0 Allergic urticaria	0.588	0.412
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.587	0.413
Q38-Q45 Other congenital malformations of the digestive system	0.587	0.413
C69.3 Choroid	0.586	0.414
C60-C63 Malignant neoplasms of male genital organs	0.586	0.414
M40.24 Other and unspecified kyphosis (Thoracic region)	0.585	0.415
M66.2 Spontaneous rupture of extensor tendons	0.584	0.416
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.584	0.416
C71.1 Frontal lobe	0.583	0.417
D43.9 Central nervous system, unspecified	0.582	0.418
D43.7 Other parts of central nervous system	0.582	0.418
D43.3 Cranial nerves	0.582	0.418
D43.1 Brain, infratentorial	0.582	0.418
M85.88 Other specified disorders of bone density and structure (Other)	0.581	0.418
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.581	0.418
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.581	0.418
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.581	0.418
M85.84 Other specified disorders of bone density and structure (Hand)	0.581	0.418
M85.83 Other specified disorders of bone density and structure (Forearm)	0.581	0.418
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.581	0.418
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.581	0.418
M60 Myositis	0.581	0.418
C80.0 Malignant neoplasm, primary site unknown, so stated	0.581	0.419
M05-M14 Inflammatory polyarthropathies	0.581	0.419
L89.9 Decubitus ulcer and pressure area, unspecified	0.581	0.419
C04.9 Floor of mouth, unspecified	0.580	0.419
L89.3 Stage IV decubitus ulcer	0.580	0.420
D03.3 Melanoma in situ of other and unspecified parts of face	0.580	0.420
M87.9 Osteonecrosis, unspecified	0.579	0.420
M25.34 Other instability of joint (Hand)	0.579	0.421
M23.3 Other meniscus derangements	0.579	0.421
M32.9 Systemic lupus erythematosus, unspecified	0.579	0.421
M32.8 Other forms of systemic lupus erythematosus	0.579	0.421
M32.0 Drug-induced systemic lupus erythematosus	0.579	0.421
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.579	0.421
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.578	0.422
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.578	0.422
M41.92 Scoliosis, unspecified (Cervical region)	0.578	0.422
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.578	0.422
L94.9 Localised connective tissue disorder, unspecified	0.577	0.423
L50.9 Urticaria, unspecified	0.576	0.424
M23.6 Other spontaneous disruption of ligament(s) of knee	0.575	0.425
M81.4 Drug-induced osteoporosis	0.575	0.425
M50-M54 Other dorsopathies	0.575	0.425
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.575	0.425
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.575	0.425
M66.5 Spontaneous rupture of unspecified tendon	0.573	0.426
M66.1 Rupture of synovium	0.573	0.426
D05 Carcinoma in situ of breast	0.574	0.426
Q78 Other osteochondrodysplasias	0.573	0.427
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.573	0.427
Q75 Other congenital malformations of skull and face bones	0.573	0.427
Q74 Other congenital malformations of limb(s)	0.573	0.427
Q73 Reduction defects of unspecified limb	0.573	0.427
Q72 Reduction defects of lower limb	0.573	0.427
Q71 Reduction defects of upper limb	0.573	0.427
Q70 Syndactyly	0.573	0.427
Q69 Polydactyly	0.573	0.427
Q68 Other congenital musculoskeletal deformities	0.573	0.427
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.572	0.428
N49.9 Inflammatory disorder of unspecified male genital organ	0.571	0.429
N49.8 Inflammatory disorders of other specified male genital organs	0.571	0.429
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.571	0.429
N49.0 Inflammatory disorders of seminal vesicle	0.571	0.429
D07.6 Other and unspecified male genital organs	0.571	0.429
D07.3 Other and unspecified female genital organs	0.571	0.429
D07.2 Vagina	0.571	0.429
D07.0 Endometrium	0.571	0.429
D03.5 Melanoma in situ of trunk	0.571	0.429
L81.7 Pigmented purpuric dermatosis	0.570	0.430
L81.6 Other disorders of diminished melanin formation	0.570	0.430
L81.5 Leukoderma, not elsewhere classified	0.570	0.430
L81.3 Cafe au lait spots	0.570	0.430
L81.1 Chloasma	0.570	0.430
L81.0 Postinflammatory hyperpigmentation	0.570	0.430
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.569	0.431
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.569	0.431
M34.9 Systemic sclerosis, unspecified	0.567	0.433
L52 Erythema nodosum	0.566	0.434
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.565	0.434
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.565	0.434
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.565	0.434
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.565	0.434
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.565	0.434
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.565	0.434
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.565	0.434
W44 Foreign body entering into or through eye or natural orifice	0.565	0.435
N48.2 Other inflammatory disorders of penis	0.565	0.435
Chapter XXII Codes for special purposes	0.565	0.435
M31.3 Wegener's granulomatosis	0.564	0.436
M30.8 Other conditions related to polyarteritis nodosa	0.563	0.437
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.563	0.437
M30.2 Juvenile polyarteritis	0.563	0.437
M24.27 Disorder of ligament (Ankle and foot)	0.562	0.438
L54 Erythema in diseases classified elsewhere	0.562	0.438
L51 Erythema multiforme	0.562	0.438
M25.78 Osteophyte (Other)	0.559	0.441
M20 Acquired deformities of fingers and toes	0.558	0.442
C71.8 Overlapping lesion of brain	0.557	0.442
M35.7 Hypermobility syndrome	0.557	0.443
M25.0 Haemarthrosis	0.557	0.443
Q65 Congenital deformities of hip	0.556	0.444
M25.37 Other instability of joint (Ankle and foot)	0.556	0.444
M40.5 Lordosis, unspecified	0.555	0.444
M40.4 Other lordosis	0.555	0.444
M40.3 Flatback syndrome	0.555	0.444
M40.1 Other secondary kyphosis	0.555	0.444
M40.0 Postural kyphosis	0.555	0.444
D00.0 Lip, oral cavity and pharynx	0.555	0.445
M24.16 Other articular cartilage disorders (Lower leg)	0.555	0.445
M25.76 Osteophyte (Lower leg)	0.555	0.445
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.554	0.446
L89.2 Stage III decubitus ulcer	0.554	0.446
Y00-Y09 Assault	0.553	0.446
Q76 Congenital malformations of spine and bony thorax	0.553	0.447

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations